Biomedical research at Oslo University Hospital
Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.
Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.
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Summary of publications:
Publications (original articles or review articles) published in 2016 from OUS - Dept. of Microbiology, Cellular Responses to DNA Damage (Bjørås)
16 publications found
N-Acetylcysteine Amide Exerts Possible Neuroprotective Effects in Newborn Pigs after Perinatal Asphyxia
Neonatology, 111 (1), 12-21
DOI 10.1159/000447255, PubMed 27497671
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition
Nature, 537 (7621), 548-552
DOI 10.1038/nature19360, PubMed 27626377
Structural and Functional Analysis of a Lytic Polysaccharide Monooxygenase Important for Efficient Utilization of Chitin in Cellvibrio japonicus
J Biol Chem, 291 (14), 7300-12
DOI 10.1074/jbc.M115.700161, PubMed 26858252
TRIM21 Immune Signaling Is More Sensitive to Antibody Affinity Than Its Neutralization Activity
J Immunol, 196 (8), 3452-3459
DOI 10.4049/jimmunol.1502601, PubMed 26962230
Neil3 induced neurogenesis protects against prion disease during the clinical phase
Sci Rep, 6, 37844
DOI 10.1038/srep37844, PubMed 27886261
Mutually exclusive RNA secondary structures regulate translation initiation of DinQ in Escherichia coli
RNA, 22 (11), 1739-1749
DOI 10.1261/rna.058461.116, PubMed 27651528
Effects of Anthocyanins on CAG Repeat Instability and Behaviour in Huntington's Disease R6/1 Mice
PLoS Curr, 8
DOI 10.1371/currents.hd.58d04209ab6d5de0844db7ef5628ff67, PubMed 27540492
Regulation of Human Endonuclease V Activity and Relocalization to Cytoplasmic Stress Granules
J Biol Chem, 291 (41), 21786-21801
DOI 10.1074/jbc.M116.730911, PubMed 27573237
Crystal structure and MD simulation of mouse EndoV reveal wedge motif plasticity in this inosine-specific endonuclease
Sci Rep, 6, 24979
DOI 10.1038/srep24979, PubMed 27108838
PML regulates neuroprotective innate immunity and neuroblast commitment in a hypoxic-ischemic encephalopathy model
Cell Death Dis, 7 (7), e2320
DOI 10.1038/cddis.2016.223, PubMed 27468695
Efficient and Reliable Production of Vectors for the Study of the Repair, Mutagenesis, and Phenotypic Consequences of Defined DNA Damage Lesions in Mammalian Cells
PLoS One, 11 (6), e0158581
DOI 10.1371/journal.pone.0158581, PubMed 27362559
Axitinib blocks Wnt/β-catenin signaling and directs asymmetric cell division in cancer
Proc Natl Acad Sci U S A, 113 (33), 9339-44
DOI 10.1073/pnas.1604520113, PubMed 27482107
3CAPS - a structural AP-site analogue as a tool to investigate DNA base excision repair
Nucleic Acids Res, 44 (5), 2187-98
DOI 10.1093/nar/gkv1520, PubMed 26733580
Enhanced base excision repair capacity in carotid atherosclerosis may protect nuclear DNA but not mitochondrial DNA
Free Radic Biol Med, 97, 386-397
DOI 10.1016/j.freeradbiomed.2016.07.001, PubMed 27381496
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice
Sci Rep, 6, 28337
DOI 10.1038/srep28337, PubMed 27328939
A potential founder variant in CARMIL2/RLTPR in three Norwegian families with warts, molluscum contagiosum, and T-cell dysfunction
Mol Genet Genomic Med, 4 (6), 604-616
DOI 10.1002/mgg3.237, PubMed 27896283