Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2017 from OUS - Dept. of Microbiology, Genome dynamics and microbial pathogenesis (Tønjum)

9 publications found

Beyene GT, Kalayou S, Riaz T, Tonjum T (2017)
Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis
BMC Microbiol, 17 (1), 96
DOI 10.1186/s12866-017-1004-8, PubMed 28431522

Birhanu AG, Yimer SA, Holm-Hansen C, Norheim G, Aseffa A, Abebe M, Tønjum T (2017)
Nε- and O-Acetylation in Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains: Proteins Involved in Bioenergetics, Virulence, and Antimicrobial Resistance Are Acetylated
J Proteome Res, 16 (11), 4045-4059
DOI 10.1021/acs.jproteome.7b00429, PubMed 28920697

Castañeda-García A, Prieto AI, Rodríguez-Beltrán J, Alonso N, Cantillon D, Costas C, Pérez-Lago L, Zegeye ED, Herranz M, Plociński P, Tonjum T, García de Viedma D, Paget M, Waddell SJ, Rojas AM, Doherty AJ, Blázquez J (2017)
A non-canonical mismatch repair pathway in prokaryotes
Nat Commun, 8, 14246
DOI 10.1038/ncomms14246, PubMed 28128207

Desler C, Lillenes MS, Tønjum T, Rasmussen LJ (2017)
The role of mitochondrial dysfunction in the progression of Alzheimer's disease
Curr Med Chem (in press)
DOI 10.2174/0929867324666170616110111, PubMed 28618998

Frye SA, Beyene GT, Namouchi A, Gómez-Muñoz M, Homberset H, Kalayou S, Riaz T, Tønjum T, Balasingham SV (2017)
The helicase DinG responds to stress due to DNA double strand breaks
PLoS One, 12 (11), e0187900
DOI 10.1371/journal.pone.0187900, PubMed 29121674

Hovland E, Beyene GT, Frye SA, Homberset H, Balasingham SV, Gómez-Muñoz M, Derrick JP, Tønjum T, Ambur OH (2017)
DprA from Neisseria meningitidis: properties and role in natural competence for transformation
Microbiology, 163 (7), 1016-1029
DOI 10.1099/mic.0.000489, PubMed 28696187

Lillenes MS, Støen M, Günther CC, Selnes P, Stenset VT, Espeseth T, Reinvang I, Fladby T, Tønjum T (2017)
Mitochondrial transcription factor A (TFAM) rs1937 and AP endonuclease 1 (APE1) rs1130409 alleles are associated with reduced cognitive performance
Neurosci Lett, 645, 46-52
DOI 10.1016/j.neulet.2017.02.062, PubMed 28242328

Norheim G, Seterelv S, Arnesen TM, Mengshoel AT, Tønjum T, Rønning JO, Eldholm V (2017)
Tuberculosis Outbreak in an Educational Institution in Norway
J Clin Microbiol, 55 (5), 1327-1333
DOI 10.1128/JCM.01152-16, PubMed 28202795

Yimer SA, Birhanu AG, Kalayou S, Riaz T, Zegeye ED, Beyene GT, Holm-Hansen C, Norheim G, Abebe M, Aseffa A, Tønjum T (2017)
Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence
Front Microbiol, 8, 795
DOI 10.3389/fmicb.2017.00795, PubMed 28536560

 
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