Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Department of Microbiology

28 publications found

Andersson DI, Balaban NQ, Baquero F, Courvalin P, Glaser P, Gophna U, Kishony R, Molin S, Tønjum T (2020)
Antibiotic resistance: turning evolutionary principles into clinical reality
FEMS Microbiol Rev, 44 (2), 171-188
DOI 10.1093/femsre/fuaa001, PubMed 31981358

Ashuro AA, Lobie TA, Ye DQ, Leng RX, Li BZ, Pan HF, Fan YG (2020)
Review on the Alteration of Gut Microbiota: The Role of HIV Infection and Old Age
AIDS Res Hum Retroviruses, 36 (7), 556-565
DOI 10.1089/AID.2019.0282, PubMed 32323556

Aulokken TM, Parkar AP, Markussen TV, Ashraf H, Mynarek GK, Nes H, Muller F, Schubert M, Jorgensen A, Blomberg SM, Bjornerheim R, Klow NE, Hopp E (2020)
Imaging of patients with COVID-19
Tidsskr. Nor. Laegeforen., 140 (8), 756-760

Backe PH, Laerdahl JK, Kittelsen LS, Dalhus B, Mørkrid L, Bjørås M (2020)
Structural basis for substrate and product recognition in human phosphoglucomutase-1 (PGM1) isoform 2, a member of the α-D-phosphohexomutase superfamily
Sci Rep, 10 (1), 5656
DOI 10.1038/s41598-020-62548-0, PubMed 32221390

Barlinn R, Trogstad L, Rollag H, Frøen F, Magnus P, Dudman SG (2020)
Parvovirus B19 DNAemia in pregnant women in relation to perinatal death: A nested case-control study within a large population-based pregnancy cohort
Acta Obstet Gynecol Scand, 99 (7), 856-864
DOI 10.1111/aogs.13801, PubMed 31925774

Boren HK, Kjostolfsen GH, Aalokken TM, Latif N, Brekke H, Lind A, Hesstvedt L (2020)
A man in his 90s with fever and dry cough
Tidsskr. Nor. Laegeforen., 140 (6), 569-573

Borén HK, Kjøstolfsen GH, Aaløkken TM, Latif N, Brekke H, Lind A, Hesstvedt L (2020)
A man in his nineties with fever and dry cough
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.20.0218, PubMed 32321232

Gilmour BC, Gudmundsrud R, Frank J, Hov A, Lautrup S, Aman Y, Røsjø H, Brenner C, Ziegler M, Tysnes OB, Tzoulis C, Omland T, Søraas A, Holmøy T, Bergersen LH, Storm-Mathisen J, Nilsen H, Fang EF (2020)
Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing
Mech Ageing Dev, 186, 111208
DOI 10.1016/j.mad.2020.111208, PubMed 31953124

Grøsvik K, Tesfahun AN, Muruzábal-Lecumberri I, Haugland GT, Leiros I, Ruoff P, Kvaløy JT, Knævelsrud I, Ånensen H, Alexeeva M, Sato K, Matsuda A, Alseth I, Klungland A, Bjelland S (2020)
The Escherichia coli alkA Gene Is Activated to Alleviate Mutagenesis by an Oxidized Deoxynucleoside
Front Microbiol, 11, 263
DOI 10.3389/fmicb.2020.00263, PubMed 32158436

Helset E, Nordøy I, Sporsem H, Bakke VD, Bugge JF, Gammelsrud KW, Zucknick M, von der Lippe E (2020)
Factors increasing the risk of inappropriate vancomycin therapy in ICU patients A prospective observational study
Acta Anaesthesiol Scand (in press)
DOI 10.1111/aas.13658, PubMed 32578201

Iversen R, Amundsen SF, Kleppa L, Fleur du Pré M, Stamnaes J, Sollid LM (2020)
Evidence that pathogenic transglutaminase 2 in celiac disease derives from enterocytes
Gastroenterology (in press)
DOI 10.1053/j.gastro.2020.04.018, PubMed 32302613

Khelik K, Sandve GK, Nederbragt AJ, Rognes T (2020)
NucBreak: location of structural errors in a genome assembly by using paired-end Illumina reads
BMC Bioinformatics, 21 (1), 66
DOI 10.1186/s12859-020-3414-0, PubMed 32085722

Kong XY, Vik ES, Nawaz MS, Berges N, Dahl TB, Vågbø C, Suganthan R, Segers F, Holm S, Quiles-Jiménez A, Gregersen I, Fladeby C, Aukrust P, Bjørås M, Klungland A, Halvorsen B, Alseth I (2020)
Deletion of Endonuclease V suppresses chemically induced hepatocellular carcinoma
Nucleic Acids Res, 48 (8), 4463-4479
DOI 10.1093/nar/gkaa115, PubMed 32083667

Lanternier F, Seidel D, Pagano L, Styczynski J, Mikulska M, Pulcini C, Maertens J, Munoz P, Garcia-Vidal C, Rijnders B, Arendrup MC, Sabino R, Verissimo C, Gaustad P, Klimko N, Arikan-Akdagli S, Arsic V, Barac A, Skiada A, Klingspor L, Herbrecht R, Donnelly P, Cornely OA, Lass-Flörl C, Lortholary O (2020)
Invasive pulmonary aspergillosis treatment duration in haematology patients in Europe: An EFISG, IDWP-EBMT, EORTC-IDG and SEIFEM survey
Mycoses, 63 (5), 420-429
DOI 10.1111/myc.13056, PubMed 32009262

Lobie TA, Woldeamanuel Y, Asrat D, Beyene D, Bjørås M, Aseffa A (2020)
Genetic diversity and drug resistance pattern of Mycobacterium tuberculosis strains isolated from pulmonary tuberculosis patients in the Benishangul Gumuz region and its surroundings, Northwest Ethiopia
PLoS One, 15 (4), e0231320
DOI 10.1371/journal.pone.0231320, PubMed 32267877

Lorentzen EM, Henriksen S, Kaur A, Kro GB, Hammarström C, Hirsch HH, Midtvedt K, Rinaldo CH (2020)
Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor
Virol J, 17 (1), 5
DOI 10.1186/s12985-019-1275-9, PubMed 31924245

Melby KK, Carlsen KL, Håland G, Samdal HH, Carlsen KH (2020)
Helicobacter pylori in early childhood and asthma in adolescence
BMC Res Notes, 13 (1), 79
DOI 10.1186/s13104-020-04941-6, PubMed 32070394

Nedal A, Ræder SB, Dalhus B, Helgesen E, Forstrøm RJ, Lindland K, Sumabe BK, Martinsen JH, Kragelund BB, Skarstad K, Bjørås M, Otterlei M (2020)
Peptides containing the PCNA interacting motif APIM bind to the β-clamp and inhibit bacterial growth and mutagenesis
Nucleic Acids Res, 48 (10), 5540-5554
DOI 10.1093/nar/gkaa278, PubMed 32347931

Nilsen J, Trabjerg E, Grevys A, Azevedo C, Brennan SO, Stensland M, Wilson J, Sand KMK, Bern M, Dalhus B, Roopenian DC, Sandlie I, Rand KD, Andersen JT (2020)
An intact C-terminal end of albumin is required for its long half-life in humans
Commun Biol, 3 (1), 181
DOI 10.1038/s42003-020-0903-7, PubMed 32313072

Sahaf Naeini A, Farooq A, Bjørås M, Wang J (2020)
IGAP-integrative genome analysis pipeline reveals new gene regulatory model associated with nonspecific TF-DNA binding affinity
Comput Struct Biotechnol J, 18, 1270-1286
DOI 10.1016/j.csbj.2020.05.024, PubMed 32612751

Sankar A, Lerdrup M, Manaf A, Johansen JV, Gonzalez JM, Borup R, Blanshard R, Klungland A, Hansen K, Andersen CY, Dahl JA, Helin K, Hoffmann ER (2020)
KDM4A regulates the maternal-to-zygotic transition by protecting broad H3K4me3 domains from H3K9me3 invasion in oocytes
Nat Cell Biol, 22 (4), 380-388
DOI 10.1038/s41556-020-0494-z, PubMed 32231309

Saue T, Bast R, Gomes ASP, Jensen HJA, Visscher L, Aucar IA, Di Remigio R, Dyall KG, Eliav E, Fasshauer E, Fleig T, Halbert L, Hedegård ED, Helmich-Paris B, Iliaš M, Jacob CR, Knecht S, Laerdahl JK, Vidal ML, Nayak MK, Olejniczak M, Olsen JMH, Pernpointner M, Senjean B, Shee A et al. (2020)
The DIRAC code for relativistic molecular calculations
J Chem Phys, 152 (20), 204104
DOI 10.1063/5.0004844, PubMed 32486677

Scheffler K, Jalland CMO, Benestad SL, Moldal T, Ersdal C, Gunnes G, Suganthan R, Bjørås M, Tranulis MA (2020)
DNA glycosylase Neil2 contributes to genomic responses in the spleen during clinical prion disease
Free Radic Biol Med, 152, 348-354
DOI 10.1016/j.freeradbiomed.2020.03.030, PubMed 32259578

Taxt AM, Avershina E, Frye SA, Naseer U, Ahmad R (2020)
Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencing
Sci Rep, 10 (1), 7622
DOI 10.1038/s41598-020-64616-x, PubMed 32376847

Tollånes MC, Bakken Kran AM, Abildsnes E, Jenum PA, Breivik AC, Sandberg S (2020)
Evaluation of eleven rapid tests for detection of antibodies against SARS-CoV-2
Clin Chem Lab Med (in press)
DOI 10.1515/cclm-2020-0628, PubMed 32598303

Vander Zanden CM, Czarny RS, Ho EN, Robertson AB, Ho PS (2020)
Structural adaptation of vertebrate endonuclease G for 5-hydroxymethylcytosine recognition and function
Nucleic Acids Res, 48 (7), 3962-3974
DOI 10.1093/nar/gkaa117, PubMed 32095813

Yang M, Lin X, Segers F, Suganthan R, Hildrestrand GA, Rinholm JE, Aas PA, Sousa MML, Holm S, Bolstad N, Warren D, Berge RK, Johansen RF, Yndestad A, Kristiansen E, Klungland A, Luna L, Eide L, Halvorsen B, Aukrust P, Bjørås M (2020)
OXR1A, a Coactivator of PRMT5 Regulating Histone Arginine Methylation
Cell Rep, 30 (12), 4165-4178.e7
DOI 10.1016/j.celrep.2020.02.063, PubMed 32209476

Aaløkken TM, Parkar AP, Markussen TV, Ashraf H, Mynarek GK, Nes H, Müller F, Schubert M, Jørgensen A, Blomberg SM, Bjørnerheim R, Kløw NE, Hopp E (2020)
Diagnostic imaging of COVID-19 patients
Tidsskr Nor Laegeforen, 140 (8)
DOI 10.4045/tidsskr.20.0332, PubMed 32463192

 
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