Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Microbiology

15 publications found

Alexeeva M, Moen MN, Grøsvik K, Tesfahun AN, Xu XM, Muruzábal-Lecumberri I, Olsen KM, Rasmussen A, Ruoff P, Kirpekar F, Klungland A, Bjelland S (2019)
Excision of uracil from DNA by hSMUG1 includes strand incision and processing
Nucleic Acids Res, 47 (2), 779-793
DOI 10.1093/nar/gky1184, PubMed 30496516

Cole MJ, Quaye N, Jacobsson S, Day M, Fagan E, Ison C, Pitt R, Seaton S, Woodford N, Stary A, Pleininger S, Crucitti T, Hunjak B, Maikanti P, Hoffmann S, Viktorova J, Buder S, Kohl P, Tzelepi E, Siatravani E, Balla E, Hauksdóttir GS, Rose L, Stefanelli P, Carannante A et al. (2019)
Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data
BMC Infect Dis, 19 (1), 281
DOI 10.1186/s12879-019-3900-z, PubMed 30909883

Hesstvedt L, Gaustad P, Müller F, Torp Andersen C, Brunborg C, Mylvaganam H, Leiva RA, Erik Berdal J, Egil Ranheim T, Johnsen BO, Falch BM, Grimnes G, Skogen V, Haarr E, Sandmo Lyngøy A, Wik Larssen K, Hannula R, Åsheim Hansen B, Nordøy I, Norwegian Fungal Network (2019)
The impact of age on risk assessment, therapeutic practice and outcome in candidemia
Infect Dis (Lond), 51 (6), 425-434
DOI 10.1080/23744235.2019.1595709, PubMed 31010380

Ianevski A, Andersen PI, Merits A, Bjørås M, Kainov D (2019)
Expanding the activity spectrum of antiviral agents
Drug Discov Today, 24 (5), 1224-1228
DOI 10.1016/j.drudis.2019.04.006, PubMed 30980905

Madhuprakash J, Dalhus B, Vaaje-Kolstad G, Sakuda S, Podile AR, Eijsink VGH, Sørlie M (2019)
Structural and Thermodynamic Signatures of Ligand Binding to the Enigmatic Chitinase D of Serratia proteamaculans
J Phys Chem B, 123 (10), 2270-2279
DOI 10.1021/acs.jpcb.8b11448, PubMed 30789732

Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Røsjø H, Louch WE (2019)
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765

Paraskevis D, Beloukas A, Stasinos K, Pantazis N, de Mendoza C, Bannert N, Meyer L, Zangerle R, Gill J, Prins M, d'Arminio Montforte A, Kran AB, Porter K, Touloumi G, CASCADE collaboration of EuroCoord (2019)
HIV-1 molecular transmission clusters in nine European countries and Canada: association with demographic and clinical factors
BMC Med, 17 (1), 4
DOI 10.1186/s12916-018-1241-1, PubMed 30616632

Quist-Paulsen E, Kran AB, Lindland ES, Ellefsen K, Sandvik L, Dunlop O, Ormaasen V (2019)
To what extent can clinical characteristics be used to distinguish encephalitis from encephalopathy of other causes? Results from a prospective observational study
BMC Infect Dis, 19 (1), 80
DOI 10.1186/s12879-018-3570-2, PubMed 30669985

Rydning SL, Koht J, Sheng Y, Sowa P, Hjorthaug HS, Wedding IM, Erichsen AK, Hovden IA, Backe PH, Tallaksen CME, Vigeland MD, Selmer KK (2019)
Biallelic POLR3A variants confirmed as a frequent cause of hereditary ataxia and spastic paraparesis
Brain, 142 (4), e12
DOI 10.1093/brain/awz041, PubMed 30847471

Segala G, Bennesch MA, Ghahhari NM, Pandey DP, Echeverria PC, Karch F, Maeda RK, Picard D (2019)
Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling
Nat Commun, 10 (1), 1833
DOI 10.1038/s41467-019-09800-y, PubMed 31015428

Shi W, Cui P, Niu H, Zhang S, Tønjum T, Zhu B, Zhang Y (2019)
Introducing RpsA Point Mutations Δ438A and D123A into the Chromosome of M. tuberculosis Confirms their Role in Causing Resistance to Pyrazinamide
Antimicrob Agents Chemother (in press)
DOI 10.1128/AAC.02681-18, PubMed 30858213

Siira L, Naseer U, Alfsnes K, Hermansen NO, Lange H, Brandal LT (2019)
Whole genome sequencing of Salmonella Chester reveals geographically distinct clusters, Norway, 2000 to 2016
Euro Surveill, 24 (4)
DOI 10.2807/1560-7917.ES.2019.24.4.1800186, PubMed 30696528

Solberg NT, Melheim M, Strand MF, Olsen PA, Krauss S (2019)
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152

Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S (2019)
Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
Aging Cell, 18 (2), e12897
DOI 10.1111/acel.12897, PubMed 30712319

Ystgaard MB, Scheffler K, Suganthan R, Bjørås M, Ranheim T, Sagen EL, Halvorsen B, Saugstad OD, Yndestad A (2019)
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362 (in press)
DOI 10.1159/000497200, PubMed 30909283

 
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