Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Department of Microbiology

27 publications found

Alexeeva M, Moen MN, Grøsvik K, Tesfahun AN, Xu XM, Muruzábal-Lecumberri I, Olsen KM, Rasmussen A, Ruoff P, Kirpekar F, Klungland A, Bjelland S (2019)
Excision of uracil from DNA by hSMUG1 includes strand incision and processing
Nucleic Acids Res, 47 (2), 779-793
DOI 10.1093/nar/gky1184, PubMed 30496516

Berdal JE, Follin-Arbelet B, Bjørnholt JV (2019)
Experiences from multiplex PCR diagnostics of faeces in hospitalised patients: clinical significance of Enteropathogenic Escherichia coli (EPEC) and culture negative campylobacter
BMC Infect Dis, 19 (1), 630
DOI 10.1186/s12879-019-4271-1, PubMed 31315581

Cole MJ, Quaye N, Jacobsson S, Day M, Fagan E, Ison C, Pitt R, Seaton S, Woodford N, Stary A, Pleininger S, Crucitti T, Hunjak B, Maikanti P, Hoffmann S, Viktorova J, Buder S, Kohl P, Tzelepi E, Siatravani E, Balla E, Hauksdóttir GS, Rose L, Stefanelli P, Carannante A et al. (2019)
Ten years of external quality assessment (EQA) of Neisseria gonorrhoeae antimicrobial susceptibility testing in Europe elucidate high reliability of data
BMC Infect Dis, 19 (1), 281
DOI 10.1186/s12879-019-3900-z, PubMed 30909883

Di Ruscio F, Guzzetta G, Bjørnholt JV, Leegaard TM, Moen AEF, Merler S, Freiesleben de Blasio B (2019)
Quantifying the transmission dynamics of MRSA in the community and healthcare settings in a low-prevalence country
Proc Natl Acad Sci U S A, 116 (29), 14599-14605
DOI 10.1073/pnas.1900959116, PubMed 31262808

Hesstvedt L, Gaustad P, Müller F, Torp Andersen C, Brunborg C, Mylvaganam H, Leiva RA, Berdal JE, Egil Ranheim T, Johnsen BO, Falch BM, Grimnes G, Skogen V, Haarr E, Sandmo Lyngøy A, Wik Larssen K, Hannula R, Åsheim Hansen B, Nordøy I, Norwegian Fungal Network (2019)
The impact of age on risk assessment, therapeutic practice and outcome in candidemia
Infect Dis (Lond), 51 (6), 425-434
DOI 10.1080/23744235.2019.1595709, PubMed 31010380

Hoydahl LS, Frick R, Sandlie I, Loset GA (2019)
Targeting the MHC Ligandome by Use of TCR-Like Antibodies
Antibodies, 8 (2), 32

Huik K, Soodla P, Pauskar M, Owen SM, Luo W, Murphy G, Jogeda EL, Kallas E, Rajasaar H, Avi R, Masciotra S, Lutsar I, Del Amo J, Meyer L, Bucher HC, Chene G, Hamouda O, Pillay D, Prins M, Rosinska M, Sabin C, Touloumi G, Porter K, Olson A, Cartier A et al. (2019)
The concordance of the limiting antigen and the Bio-Rad avidity assays in persons from Estonia infected mainly with HIV-1 CRF06_cpx
PLoS One, 14 (5), e0217048

Ianevski A, Andersen PI, Merits A, Bjørås M, Kainov D (2019)
Expanding the activity spectrum of antiviral agents
Drug Discov Today, 24 (5), 1224-1228
DOI 10.1016/j.drudis.2019.04.006, PubMed 30980905

Iversen R, Roy B, Stamnaes J, Høydahl LS, Hnida K, Neumann RS, Korponay-Szabó IR, Lundin KEA, Sollid LM (2019)
Efficient T cell-B cell collaboration guides autoantibody epitope bias and onset of celiac disease
Proc Natl Acad Sci U S A, 116 (30), 15134-15139
DOI 10.1073/pnas.1901561116, PubMed 31285344

Lång A, Lång E, Bøe SO (2019)
PML Bodies in Mitosis
Cells, 8 (8)
DOI 10.3390/cells8080893, PubMed 31416160

Madhuprakash J, Dalhus B, Vaaje-Kolstad G, Sakuda S, Podile AR, Eijsink VGH, Sørlie M (2019)
Structural and Thermodynamic Signatures of Ligand Binding to the Enigmatic Chitinase D of Serratia proteamaculans
J Phys Chem B, 123 (10), 2270-2279
DOI 10.1021/acs.jpcb.8b11448, PubMed 30789732

Mirinaviciute G, Barlinn R, Gjeruldsen Dudman S, Flem E (2019)
Immunity to varicella zoster virus among pregnant women in the Norwegian Mother and Child Cohort Study
PLoS One, 14 (8), e0221084
DOI 10.1371/journal.pone.0221084, PubMed 31408478

Ottesen AH, Carlson CR, Eken OS, Sadredini M, Myhre PL, Shen X, Dalhus B, Laver DR, Lunde PK, Kurola J, Lunde M, Hoff JE, Godang K, Sjaastad I, Pettilä V, Stridsberg M, Lehnart SE, Edwards AG, Lunde IG, Omland T, Stokke MK, Christensen G, Røsjø H, Louch WE (2019)
Secretoneurin Is an Endogenous Calcium/Calmodulin-Dependent Protein Kinase II Inhibitor That Attenuates Ca2+-Dependent Arrhythmia
Circ Arrhythm Electrophysiol, 12 (4), e007045
DOI 10.1161/CIRCEP.118.007045, PubMed 30943765

Paraskevis D, Beloukas A, Stasinos K, Pantazis N, de Mendoza C, Bannert N, Meyer L, Zangerle R, Gill J, Prins M, d'Arminio Montforte A, Kran AB, Porter K, Touloumi G, CASCADE collaboration of EuroCoord (2019)
HIV-1 molecular transmission clusters in nine European countries and Canada: association with demographic and clinical factors
BMC Med, 17 (1), 4
DOI 10.1186/s12916-018-1241-1, PubMed 30616632

Prikrylova T, Robertson J, Ferrucci F, Konorska D, Aanes H, Manaf A, Zhang B, Vågbø CB, Kuśnierczyk A, Gilljam KM, Løvkvam-Køster C, Otterlei M, Dahl JA, Enserink J, Klungland A, Robertson AB (2019)
5-hydroxymethylcytosine Marks Mammalian Origins Acting as a Barrier to Replication
Sci Rep, 9 (1), 11065
DOI 10.1038/s41598-019-47528-3, PubMed 31363131

Quist-Paulsen E, Kran AB, Lindland ES, Ellefsen K, Sandvik L, Dunlop O, Ormaasen V (2019)
To what extent can clinical characteristics be used to distinguish encephalitis from encephalopathy of other causes? Results from a prospective observational study
BMC Infect Dis, 19 (1), 80
DOI 10.1186/s12879-018-3570-2, PubMed 30669985

Ramberg BT, Halvorsen M, Før de RD, Ambur OH, Borge AIH (2019)
Co-authorship - a bone of contention
Tidsskr Nor Laegeforen, 139 (11)
DOI 10.4045/tidsskr.19.0145, PubMed 31429235

Scheffler K, Bjørås KØ, Bjørås M (2019)
Diverse functions of DNA glycosylases processing oxidative base lesions in brain
DNA Repair (Amst), 102665 (in press)
DOI 10.1016/j.dnarep.2019.102665, PubMed 31327582

Segala G, Bennesch MA, Ghahhari NM, Pandey DP, Echeverria PC, Karch F, Maeda RK, Picard D (2019)
Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling
Nat Commun, 10 (1), 1833
DOI 10.1038/s41467-019-09800-y, PubMed 31015428

Shi W, Cui P, Niu H, Zhang S, Tønjum T, Zhu B, Zhang Y (2019)
Introducing RpsA Point Mutations Δ438A and D123A into the Chromosome of Mycobacterium tuberculosis Confirms Their Role in Causing Resistance to Pyrazinamide
Antimicrob Agents Chemother, 63 (6)
DOI 10.1128/AAC.02681-18, PubMed 30858213

Siira L, Naseer U, Alfsnes K, Hermansen NO, Lange H, Brandal LT (2019)
Whole genome sequencing of Salmonella Chester reveals geographically distinct clusters, Norway, 2000 to 2016
Euro Surveill, 24 (4)
DOI 10.2807/1560-7917.ES.2019.24.4.1800186, PubMed 30696528

Smatlikova P, Askeland G, Vaskovicova M, Klima J, Motlik J, Eide L, Ellederová Z (2019)
Age-Related Oxidative Changes in Primary Porcine Fibroblasts Expressing Mutated Huntingtin
Neurodegener Dis, 19 (1), 22-34
DOI 10.1159/000500091, PubMed 31167196

Solberg NT, Melheim M, Strand MF, Olsen PA, Krauss S (2019)
MEK Inhibition Induces Canonical WNT Signaling through YAP in KRAS Mutated HCT-15 Cells, and a Cancer Preventive FOXO3/FOXM1 Ratio in Combination with TNKS Inhibition
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020164, PubMed 30717152

Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S (2019)
Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
Aging Cell, 18 (2), e12897
DOI 10.1111/acel.12897, PubMed 30712319

Vinje T, Laerdahl JK, Bjune K, Leren TP, Strøm TB (2019)
Characterization of the mechanisms by which missense mutations in the lysosomal acid lipase gene disrupt enzymatic activity
Hum Mol Genet (in press)
DOI 10.1093/hmg/ddz114, PubMed 31131398

Yang K, Lauritzen KH, Olsen MB, Dahl TB, Ranheim T, Ahmed MS, Attramadal H, Aukrust P, Halvorsen B, Nyman TA, Sandanger Ø, Yndestad A (2019)
Low Cellular NAD+ Compromises Lipopolysaccharide-Induced Inflammatory Responses via Inhibiting TLR4 Signal Transduction in Human Monocytes
J Immunol (in press)
DOI 10.4049/jimmunol.1801382, PubMed 31427442

Ystgaard MB, Scheffler K, Suganthan R, Bjørås M, Ranheim T, Sagen EL, Halvorsen B, Saugstad OD, Yndestad A (2019)
Neuromodulatory Effect of NLRP3 and ASC in Neonatal Hypoxic Ischemic Encephalopathy
Neonatology, 115 (4), 355-362
DOI 10.1159/000497200, PubMed 30909283

 
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