Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Division of Laboratory Medicine

30 publications found

Bains SJ, Niehusmann PF, Meling TR, Saxhaug C, Züchner M, Brandal P (2019)
Disseminated central nervous system hemangioblastoma in a patient with no clinical or genetic evidence of von Hippel-Lindau disease-a case report and literature review
Acta Neurochir (Wien) (in press)
DOI 10.1007/s00701-019-03800-z, PubMed 30652202

Binzer-Panchal A, Hardell E, Viklund B, Ghaderi M, Bosse T, Nucci MR, Lee CH, Hollfelder N, Corcoran P, Gonzalez-Molina J, Moyano-Galceran L, Bell DA, Schoolmeester JK, Måsbäck A, Kristensen GB, Davidson B, Lehti K, Isaksson A, Carlson JW (2019)
Integrated Molecular Analysis of Undifferentiated Uterine Sarcomas Reveals Clinically Relevant Molecular Subtypes
Clin Cancer Res (in press)
DOI 10.1158/1078-0432.CCR-18-2792, PubMed 30617134

Brennecke P, Rasina D, Aubi O, Herzog K, Landskron J, Cautain B, Vicente F, Quintana J, Mestres J, Stechmann B, Ellinger B, Brea J, Kolanowski JL, Pilarski R, Orzaez M, Pineda-Lucena A, Laraia L, Nami F, Zielenkiewicz P, Paruch K, Hansen E, von Kries JP, Neuenschwander M, Specker E, Bartunek P et al. (2019)
EU-OPENSCREEN: A Novel Collaborative Approach to Facilitate Chemical Biology
SLAS Discov, 2472555218816276 (in press)
DOI 10.1177/2472555218816276, PubMed 30616481

Bruun LD, Kjeldstadli K, Temte V, Birdal M, Bachs L, Langødegård M, Strand DH, Gaare KI, Øiestad E, Høiseth G (2019)
Detection Time of Oxazepam and Zopiclone in Urine and Oral Fluid after Experimental Oral Dosing
J Anal Toxicol (in press)
DOI 10.1093/jat/bky083, PubMed 30615130

Buer LCT, Moum BA, Cvancarova M, Warren DJ, Bolstad N, Medhus AW, Høivik ML (2019)
Real world data on effectiveness, safety and therapeutic drug monitoring of vedolizumab in patients with inflammatory bowel disease. A single center cohort
Scand J Gastroenterol, 1-8 (in press)
DOI 10.1080/00365521.2018.1548646, PubMed 30650312

Forsberg F, Brunet A, Ali TML, Collas P (2019)
Interplay of lamin A and lamin B LADs on the radial positioning of chromatin
Nucleus (in press)
DOI 10.1080/19491034.2019.1570810, PubMed 30663495

Gjersing L, Bretteville-Jensen AL, Furuhaugen H, Gjerde H (2019)
Illegal substance use among 1,309 music festival attendees: An investigation using oral fluid sample drug tests, breathalysers and questionnaires
Scand J Public Health, 1403494818821481 (in press)
DOI 10.1177/1403494818821481, PubMed 30632949

Gravensteen IK, Ekeberg Ø, Thiblin I, Helweg-Larsen K, Hem E, Rogde S, Tøllefsen IM (2019)
Psychoactive substances in natural and unnatural deaths in Norway and Sweden - a study on victims of suicide and accidents compared with natural deaths in psychiatric patients
BMC Psychiatry, 19 (1), 33
DOI 10.1186/s12888-019-2015-9, PubMed 30658618

Jamt REG, Gjerde H, Romeo G, Bogstrand ST (2019)
Association between alcohol and drug use and arrest for driving under the influence after crash involvement in a rural area of Norway: a case-control study
BMJ Open, 9 (1), e023563
DOI 10.1136/bmjopen-2018-023563, PubMed 30610022

Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S et al. (2019)
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet (in press)
DOI 10.1038/s41588-018-0311-9, PubMed 30617256

Josefsson SE, Beiske K, Blaker YN, Førsund MS, Holte H, Østenstad B, Kimby E, Köksal H, Wälchli S, Bai B, Smeland EB, Levy R, Kolstad A, Huse K, Myklebust JH (2019)
TIGIT and PD-1 mark intratumoral T cells with reduced effector function in B-cell non-Hodgkin lymphoma
Cancer Immunol Res (in press)
DOI 10.1158/2326-6066.CIR-18-0351, PubMed 30659053

Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
Sci Rep, 9 (1), 167
DOI 10.1038/s41598-018-35367-7, PubMed 30655568

Klaasen RA, Egeland EJ, Chan J, Midtvedt K, Svensson M, Bolstad N, Fellström B, Holdaas H, Åsberg A, Bergan S, Vethe NT, Warren DJ (2019)
A Fully Automated Method for the Determination of Serum Belatacept and Its Application in a Pharmacokinetic Investigation in Renal Transplant Recipients
Ther Drug Monit, 41 (1), 11-18
DOI 10.1097/FTD.0000000000000580, PubMed 30633722

Kraby MR, Opdahl S, Russnes HG, Bofin AM (2019)
Microvessel density in breast cancer: the impact of field area on prognostic informativeness
J Clin Pathol (in press)
DOI 10.1136/jclinpath-2018-205536, PubMed 30630872

Lenggenhager D, Amrutkar M, Sántha P, Aasrum M, Löhr JM, Gladhaug IP, Verbeke CS (2019)
Commonly Used Pancreatic Stellate Cell Cultures Differ Phenotypically and in Their Interactions with Pancreatic Cancer Cells
Cells, 8 (1)
DOI 10.3390/cells8010023, PubMed 30621293

Lillejordet E, Rashid HU, Evang JA, Taraldsrud E, Gunnarsson R (2019)
Kvinne i 40-årene med influensasymptomer og hevelse i armen
Tidsskr Nor Laegeforen, 139 (1)
DOI 10.4045/tidsskr.17.0170, PubMed 30644687

Mooij P, Grødeland G, Koopman G, Andersen TK, Mortier D, Nieuwenhuis IG, Verschoor EJ, Fagrouch Z, Bogers WM, Bogen B (2019)
Needle-free delivery of DNA: Targeting of hemagglutinin to MHC class II molecules protects rhesus macaques against H1N1 influenza
Vaccine (in press)
DOI 10.1016/j.vaccine.2018.12.049, PubMed 30638800

Murali R, Davidson B, Fadare O, Carlson JA, Crum CP, Gilks CB, Irving JA, Malpica A, Matias-Guiu X, McCluggage WG, Mittal K, Oliva E, Parkash V, Rutgers JKL, Staats PN, Stewart CJR, Tornos C, Soslow RA (2019)
High-grade Endometrial Carcinomas: Morphologic and Immunohistochemical Features, Diagnostic Challenges and Recommendations
Int J Gynecol Pathol, 38 Suppl 1, S40-S63
DOI 10.1097/PGP.0000000000000491, PubMed 30550483

Myhr KM, Torkildsen Ø, Lossius A, Bø L, Holmøy T (2019)
B cell depletion in the treatment of multiple sclerosis
Expert Opin Biol Ther (in press)
DOI 10.1080/14712598.2019.1568407, PubMed 30632834

Mäki-Marttunen T, Krull F, Bettella F, Hagen E, Næss S, Ness TV, Moberget T, Elvsåshagen T, Metzner C, Devor A, Edwards AG, Fyhn M, Djurovic S, Dale AM, Andreassen OA, Einevoll GT (2019)
Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations
Cereb Cortex, 29 (2), 875-891
DOI 10.1093/cercor/bhy291, PubMed 30475994

Paraskevis D, Beloukas A, Stasinos K, Pantazis N, de Mendoza C, Bannert N, Meyer L, Zangerle R, Gill J, Prins M, d'Arminio Montforte A, Kran AB, Porter K, Touloumi G, CASCADE collaboration of EuroCoord (2019)
HIV-1 molecular transmission clusters in nine European countries and Canada: association with demographic and clinical factors
BMC Med, 17 (1), 4
DOI 10.1186/s12916-018-1241-1, PubMed 30616632

Sanyal N, Lo MT, Kauppi K, Djurovic S, Andreassen OA, Johnson VE, Chen CH (2019)
GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies
Bioinformatics, 35 (1), 1-11
DOI 10.1093/bioinformatics/bty472, PubMed 29931045

Shaw A, Hoffecker IT, Smyrlaki I, Rosa J, Grevys A, Bratlie D, Sandlie I, Michaelsen TE, Andersen JT, Högberg B (2019)
Binding to nanopatterned antigens is dominated by the spatial tolerance of antibodies
Nat Nanotechnol (in press)
DOI 10.1038/s41565-018-0336-3, PubMed 30643273

Skulberg AK, Åsberg A, Khiabani HZ, Røstad H, Tylleskar I, Dale O (2019)
Pharmacokinetics of a novel, approved, 1.4 mg intranasal naloxone formulation for reversal of opioid overdose- a randomised controlled trial
Addiction (in press)
DOI 10.1111/add.14552, PubMed 30644628

Smeland OB, Bahrami S, Frei O, Shadrin A, O'Connell K, Savage J, Watanabe K, Krull F, Bettella F, Steen NE, Ueland T, Posthuma D, Djurovic S, Dale AM, Andreassen OA (2019)
Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry (in press)
DOI 10.1038/s41380-018-0332-x, PubMed 30610197

Tao XY, Li ML, Wang Q, Baima C, Hong M, Li W, Wu YB, Li YR, Zhao YM, Rayner S, Zhu WY (2019)
The reemergence of human rabies and emergence of an Indian subcontinent lineage in Tibet, China
PLoS Negl Trop Dis, 13 (1), e0007036 (in press)
DOI 10.1371/journal.pntd.0007036, PubMed 30640911

Thorgersen EB, Barratt-Due A, Haugaa H, Harboe M, Pischke SE, Nilsson PH, Mollnes TE (2019)
The role of complement in liver injury, regeneration and transplantation
Hepatology (in press)
DOI 10.1002/hep.30508, PubMed 30653682

Thorkildsen J, Taksdal I, Bjerkehagen B, Haugland HK, Børge Johannesen T, Viset T, Norum OJ, Bruland Ø, Zaikova O (2019)
Chondrosarcoma in Norway 1990-2013; an epidemiological and prognostic observational study of a complete national cohort
Acta Oncol, 1-10 (in press)
DOI 10.1080/0284186X.2018.1554260, PubMed 30632866

Traaen GM, Aakerøy L, Hunt TE, Øverland B, Lyseggen E, Aukrust P, Ueland T, Helle-Valle T, Steinshamn S, Edvardsen T, Zaré HK, Aakhus S, Akre H, Anfinsen OG, Loennechen JP, Gullestad L (2019)
Treatment of Sleep Apnea in Patients with Paroxysmal Atrial Fibrillation: Design and Rationale of a Randomized Controlled Trial
Scand Cardiovasc J, 1-20 (in press)
DOI 10.1080/14017431.2019.1567933, PubMed 30638392

Vethe NT, Munkhaugen J, Andersen AM, Husebye E, Bergan S (2019)
A Method for Direct Monitoring of Atorvastatin Adherence in Cardiovascular Disease Prevention: Quantification of the Total Exposure to Parent Drug and Major Metabolites Using 2-Channel Chromatography and Tandem Mass Spectrometry
Ther Drug Monit, 41 (1), 19-28
DOI 10.1097/FTD.0000000000000578, PubMed 30633723

 
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