Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

Click here to see hierarchical division and subunit overview

Summary of publications:

Publications (original articles or review articles) published in 2020 from OUS - Division of Cardiovascular and Pulmonary Diseases

122 publications found

Abadpour S, Tyrberg B, Schive SW, Huldt CW, Gennemark P, Ryberg E, Rydén-Bergsten T, Smith DM, Korsgren O, Skrtic S, Scholz H, Winzell MS (2020)
Inhibition of the prostaglandin D2-GPR44/DP2 axis improves human islet survival and function
Diabetologia, 63 (7), 1355-1367
DOI 10.1007/s00125-020-05138-z, PubMed 32350565

Abrahamsen R, Gundersen GF, Svendsen MV, Klepaker G, Kongerud J, Fell AKM (2020)
Possible risk factors for poor asthma control assessed in a cross-sectional population-based study from Telemark, Norway
PLoS One, 15 (5), e0232621
DOI 10.1371/journal.pone.0232621, PubMed 32396562

Ajmone Marsan N, Michalski B, Cameli M, Podlesnikar T, Manka R, Sitges M, Dweck MR, Haugaa KH (2020)
EACVI survey on standardization of cardiac chambers quantification by transthoracic echocardiography
Eur Heart J Cardiovasc Imaging, 21 (2), 119-123
DOI 10.1093/ehjci/jez297, PubMed 31819943

Alfonso JH, Afanou AK, Holm JØ, Stylianou E (2020)
Skin bioengineering in the diagnosis of occupational protein contact dermatitis
Occup Med (Lond), 70 (4), 282-285
DOI 10.1093/occmed/kqaa005, PubMed 32009172

Altara R, da Silva GJJ, Frisk M, Spelta F, Zouein FA, Louch WE, Booz GW, Cataliotti A (2020)
Cardioprotective Effects of the Novel Compound Vastiras in a Preclinical Model of End-Organ Damage
Hypertension, 75 (5), 1195-1204
DOI 10.1161/HYPERTENSIONAHA.120.14704, PubMed 32200677

Amini M, Niemi E, Hisdal J, Kalvøy H, Tronstad C, Scholz H, Rosales A, Martinsen ØG (2020)
Monitoring the quality of frozen-thawed venous segments using bioimpedance spectroscopy
Physiol Meas, 41 (4), 044008
DOI 10.1088/1361-6579/ab85b7, PubMed 32235072

Andersen ØS, Krogh MR, Boe E, Storsten P, Aalen JM, Larsen CK, Skulstad H, Odland HH, Smiseth OA, Remme EW (2020)
Left bundle branch block increases left ventricular diastolic pressure during tachycardia due to incomplete relaxation
J Appl Physiol (1985), 128 (4), 729-738
DOI 10.1152/japplphysiol.01002.2018, PubMed 31999529

Anstrom KJ, Noth I, Flaherty KR, Edwards RH, Albright J, Baucom A, Brooks M, Clark AB, Clausen ES, Durheim MT, Kim DY, Kirchner J, Oldham JM, Snyder LD, Wilson AM, Wisniewski SR, Yow E, Martinez FJ, CleanUP-IPF Study Team (2020)
Design and rationale of a multi-center, pragmatic, open-label randomized trial of antimicrobial therapy - the study of clinical efficacy of antimicrobial therapy strategy using pragmatic design in Idiopathic Pulmonary Fibrosis (CleanUP-IPF) clinical trial
Respir Res, 21 (1), 68
DOI 10.1186/s12931-020-1326-1, PubMed 32164673

Aslam S, Grossi P, Schlendorf KH, Holm AM, Woolley AE, Blumberg E, Mehra MR, working group members (2020)
Utilization of hepatitis C virus-infected organ donors in cardiothoracic transplantation: An ISHLT expert consensus statement
J Heart Lung Transplant, 39 (5), 418-432
DOI 10.1016/j.healun.2020.03.004, PubMed 32362393

Badano LP, Muraru D, Parati G, Haugaa K, Voigt JU (2020)
How to do right ventricular strain
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa126, PubMed 32504092

Berg-Knudsen TB, Ingvaldsen CA, Mørk G, Tønseth KA (2020)
Excision of skin lesions
Tidsskr Nor Laegeforen, 140 (10)
DOI 10.4045/tidsskr.20.0060, PubMed 32602315

Bergh N, Gude E, Bartfay SE, K Andreassen A, Arora S, Dahlberg P, Dellgren G, Gullestad L, Gustafsson F, Karasson K, Rådegran G, Bollano E, Andersson B (2020)
Invasive haemodynamics in de novo everolimus vs. calcineurin inhibitor heart transplant recipients
ESC Heart Fail, 7 (2), 567-576
DOI 10.1002/ehf2.12608, PubMed 32059083

Berntsen KS, Raastad T, Marstein H, Kirkhus E, Merckoll E, Cumming KT, Flatø B, Sjaastad I, Sanner H (2020)
Functional and Structural Adaptations of Skeletal Muscle in Long-Term Juvenile Dermatomyositis: A Controlled Cross-Sectional Study
Arthritis Rheumatol, 72 (5), 837-848
DOI 10.1002/art.41174, PubMed 31746550

Bjerring AW, Landgraff HE, Leirstein S, Haugaa KH, Edvardsen T, Sarvari SI, Hallén J (2020)
From talented child to elite athlete: The development of cardiac morphology and function in a cohort of endurance athletes from age 12 to 18
Eur J Prev Cardiol, UNSP 2047487320921317
DOI 10.1177/2047487320921317, PubMed 32345054

Bjorlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
A man in his 50s with abdominal pain, itching and weight loss
Tidsskr. Nor. Laegeforen., 140 (3), 268-272

Bjørlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
A man in his fifties with abdominal pain, itching and weight loss
Tidsskr Nor Laegeforen, 140 (3)
DOI 10.4045/tidsskr.19.0390, PubMed 32105028

Bjørlykke KH, Eftang LL, Grzyb K, Line PD, Lassen K, Jahnsen J (2020)
Rettelse: En mann i 50-årene med magesmerter, kløe og vekttap
Tidsskr Nor Laegeforen, 140 (4)
DOI 10.4045/tidsskr.20.0137, PubMed 32192268

Broch K, Gude E, Karason K, Dellgren G, Rådegran G, Gjesdal G, Gustafsson F, Eiskjaer H, Lommi J, Lemström KB, Andreassen AK, Gullestad L (2020)
Cholesterol-lowering with EVOLocumab to prevent cardiac allograft Vasculopathy in De-novo heart transplant recipients: Design of the randomized controlled EVOLVD trial
Clin Transplant, e13984 (in press)
DOI 10.1111/ctr.13984, PubMed 32445429

Brustugun OT, Sørhaug S, Grønberg BH, Aanerud M, Al-Zubayidy MMZ, Fjellbirkeland L, Helland Å, Berg J, Andreassen B, Paulsen EE, Haram PM, Ashraf H, Wahl SGF (2020)
Lungekreft: Forbedret prognose gir kapasitetsutfordringer
Tidsskr Nor Laegeforen, 140 (5)
DOI 10.4045/tidsskr.20.0014, PubMed 32238965

Bye A, Klevjer M, Ryeng E, Silva GJJD, Moreira JBN, Stensvold D, Wisløff U (2020)
Identification of novel genetic variants associated with cardiorespiratory fitness
Prog Cardiovasc Dis (in press)
DOI 10.1016/j.pcad.2020.02.001, PubMed 32035127

Chivulescu M, Lie ØH, Popescu BA, Skulstad H, Edvardsen T, Jurcut RO, Haugaa KH (2020)
High penetrance and similar disease progression in probands and in family members with arrhythmogenic cardiomyopathy
Eur Heart J, 41 (14), 1401-1410
DOI 10.1093/eurheartj/ehz570, PubMed 31504415

Corrado D, Perazzolo Marra M, Zorzi A, Beffagna G, Cipriani A, Lazzari M, Migliore F, Pilichou K, Rampazzo A, Rigato I, Rizzo S, Thiene G, Anastasakis A, Asimaki A, Bucciarelli-Ducci C, Haugaa KH, Marchlinski FE, Mazzanti A, McKenna WJ, Pantazis A, Pelliccia A, Schmied C, Sharma S, Wichter T, Bauce B et al. (2020)
Diagnosis of arrhythmogenic cardiomyopathy: The Padua criteria
Int J Cardiol (in press)
DOI 10.1016/j.ijcard.2020.06.005, PubMed 32561223

Corrado D, van Tintelen PJ, McKenna WJ, Hauer RNW, Anastastakis A, Asimaki A, Basso C, Bauce B, Brunckhorst C, Bucciarelli-Ducci C, Duru F, Elliott P, Hamilton RM, Haugaa KH, James CA, Judge D, Link MS, Marchlinski FE, Mazzanti A, Mestroni L, Pantazis A, Pelliccia A, Marra MP, Pilichou K, Platonov PGA et al. (2020)
Arrhythmogenic right ventricular cardiomyopathy: evaluation of the current diagnostic criteria and differential diagnosis
Eur Heart J, 41 (14), 1414-1429
DOI 10.1093/eurheartj/ehz669, PubMed 31637441

Cosyns B, Lochy S, Luchian ML, Gimelli A, Pontone G, Allard SD, de Mey J, Rosseel P, Dweck M, Petersen SE, Edvardsen T (2020)
The role of cardiovascular imaging for myocardial injury in hospitalized COVID-19 patients
Eur Heart J Cardiovasc Imaging, 21 (7), 709-714
DOI 10.1093/ehjci/jeaa136, PubMed 32391912

Danielsen SO, Moons P, Leegaard M, Solheim S, Tønnessen T, Lie I (2020)
Facilitators of and barriers to reducing thirty-day readmissions and improving patient-reported outcomes after surgical aortic valve replacement: a process evaluation of the AVRre trial
BMC Health Serv Res, 20 (1), 256
DOI 10.1186/s12913-020-05125-5, PubMed 32220252

De Bortoli MM, Fell AKM, Svendsen MV, Henneberger PK, Kongerud J, Oellingrath IM (2020)
Lifestyle, sick leave and work ability among Norwegian employees with asthma-A population-based cross-sectional survey conducted in Telemark County, Norway
PLoS One, 15 (4), e0231710
DOI 10.1371/journal.pone.0231710, PubMed 32302337

Dellgren G, Lund TK, Raivio P, Leuckfeld I, Svahn J, Magnusson J, Riise GC (2020)
Design and Rationale of a Scandinavian Multicenter Randomized Study Evaluating if Once-Daily Tacrolimus Versus Twice-Daily Cyclosporine Reduces the 3-year Incidence of Chronic Lung Allograft Dysfunction After Lung Transplantation (ScanCLAD Study)
Adv Ther, 37 (3), 1260-1275
DOI 10.1007/s12325-020-01224-1, PubMed 31993943

Duchenne J, Aalen JM, Cvijic M, Larsen CK, Galli E, Bézy S, Beela AS, Ünlü S, Pagourelias ED, Winter S, Hopp E, Kongsgård E, Donal E, Fehske W, Smiseth OA, Voigt JU (2020)
Acute redistribution of regional left ventricular work by cardiac resynchronization therapy determines long-term remodelling
Eur Heart J Cardiovasc Imaging, 21 (6), 619-628
DOI 10.1093/ehjci/jeaa003, PubMed 32031587

Dueland S, Syversveen T, Solheim JM, Solberg S, Grut H, Bjørnbeth BA, Hagness M, Line PD (2020)
Survival Following Liver Transplantation for Patients With Nonresectable Liver-only Colorectal Metastases
Ann Surg, 271 (2), 212-218
DOI 10.1097/SLA.0000000000003404, PubMed 31188200

Durheim MT, Hoffmann-Vold AM, Eagan TM, Hovden AO, Lund MB, Bjerke G, Birring SS, Jonassen TM, Johansen OE, Sjåheim T (2020)
ILD-specific health-related quality of life in systemic sclerosis-associated ILD compared with IPF
BMJ Open Respir Res, 7 (1)
DOI 10.1136/bmjresp-2020-000598, PubMed 32576559

Dweck MR, Bularga A, Hahn RT, Bing R, Lee KK, Chapman AR, White A, Salvo GD, Sade LE, Pearce K, Newby DE, Popescu BA, Donal E, Cosyns B, Edvardsen T, Mills NL, Haugaa K (2020)
Global evaluation of echocardiography in patients with COVID-19
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa178, PubMed 32556199

Edvardsen T, Cosyns B, Popescu BA, Maurer G (2020)
Maurizio Galderisi (31 August 1954-27 March 2020)
Eur Heart J, 41 (25), 2350-2351
DOI 10.1093/eurheartj/ehaa268, PubMed 32608492

Edvardsen T, Cosyns B, Popescu BA, Maurer G (2020)
Maurizio Galderisi (31 August 1954-27 March 2020)
Eur Heart J Cardiovasc Imaging, 21 (6), 591
DOI 10.1093/ehjci/jeaa077, PubMed 32432321

Espinoza A, Kerans V, Bugge JF, Skulstad H, Halvorsen PS (2020)
Left Ventricular Function During Epinephrine Stimulation and Hypothermia: Effects at Spontaneous and Paced Heart Rates in a Porcine Model
Ther Hypothermia Temp Manag
DOI 10.1089/ther.2019.0035, PubMed 31916922

Frafjord A, Skarshaug R, Hammarström C, Stankovic B, Dorg LT, Aamodt H, Woldbaek PR, Helland Å, Brustugun OT, Øynebråten I, Corthay A (2020)
Antibody combinations for optimized staining of macrophages in human lung tumours
Scand J Immunol, 92 (1), e12889
DOI 10.1111/sji.12889, PubMed 32299134

Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
PLoS One, 15 (5), e0232739
DOI 10.1371/journal.pone.0232739, PubMed 32437393

George MJ, Kleveland O, Garcia-Hernandez J, Palmen J, Lovering R, Wiseth R, Aukrust P, Engmann J, Damås JK, Hingorani AD, Gullestad L, Casas JP, Ueland T (2020)
Novel Insights Into the Effects of Interleukin 6 Antagonism in Non-ST-Segment-Elevation Myocardial Infarction Employing the SOMAscan Proteomics Platform
J Am Heart Assoc, 9 (12), e015628
DOI 10.1161/JAHA.119.015628, PubMed 32515246

González A, Nome CG, Bendiksen BA, Sjaastad I, Zhang L, Aleksandersen M, Taubøll E, Aurlien D, Heuser K (2020)
Assessment of cardiac structure and function in a murine model of temporal lobe epilepsy
Epilepsy Res, 161, 106300
DOI 10.1016/j.eplepsyres.2020.106300, PubMed 32126491

Gude E, Hoel TN, Sørensen G, Broch K, Meyer A, Fiane AE (2020)
Long-term continuous flow mechanical biventricular support: 9 years and counting
Interact Cardiovasc Thorac Surg, 30 (1), 81-84
DOI 10.1093/icvts/ivz231, PubMed 31580433

Gul KA, Strand J, Pettersen RD, Brun H, Abrahamsen TG (2020)
T-cell Receptor Excision Circles in Newborns with Heart Defects
Pediatr Cardiol, 41 (4), 809-815
DOI 10.1007/s00246-020-02317-y, PubMed 32166410

Gustafsson F, Andreassen AK, Andersson B, Eiskjær H, Rådegran G, Gude E, Jansson K, Solbu D, Karason K, Arora S, Dellgren G, Gullestad L, SCHEDULE (Scandinavian heart transplant everolimus de novo study with early calcineurin inhibitors avoidance) Investigators* (2020)
Everolimus Initiation With Early Calcineurin Inhibitor Withdrawal in De Novo Heart Transplant Recipients: Long-term Follow-up From the Randomized SCHEDULE Study
Transplantation, 104 (1), 154-164
DOI 10.1097/TP.0000000000002702, PubMed 30893292

Habeichi NJ, Mroueh A, Kaplan A, Ghali R, Al-Awassi H, Tannous C, Husari A, Jurjus A, Altara R, Booz GW, El-Yazbi A, Zouein FA (2020)
Sex-based differences in myocardial infarction-induced kidney damage following cigarette smoking exposure: more renal protection in premenopausal female mice
Biosci Rep, 40 (6)
DOI 10.1042/BSR20193229, PubMed 32519752

Hamre CFB, Kvammen EMH, Vinge LE, Skeie AT, Hompland I (2020)
Sarkom i hjertet
Tidsskr Nor Laegeforen, 140 (6)
DOI 10.4045/tidsskr.19.0455, PubMed 32321220

Harbo MB, Nordén ES, Narula J, Sjaastad I, Espe EKS (2020)
Quantifying left ventricular function in heart failure: What makes a clinically valuable parameter?
Prog Cardiovasc Dis (in press)
DOI 10.1016/j.pcad.2020.05.007, PubMed 32502560

Haugaa KH, Leren IS (2020)
Electro-mechanics or mechano-electrics, an intricate interplay
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa186, PubMed 32577742

Hazen J, Vistnes M, Barca ML, Eldholm RS, Persson K, Brækhus A, Saltvedt I, Selbæk G, Engedal K, Knapskog AB (2020)
The Association Between Circulating Inflammatory Markers and the Progression of Alzheimer Disease in Norwegian Memory Clinic Patients With Mild Cognitive Impairment or Dementia
Alzheimer Dis Assoc Disord, 34 (1), 47-53
DOI 10.1097/WAD.0000000000000342, PubMed 31414991

Herum KM, Romaine A, Wang A, Melleby AO, Strand ME, Pacheco J, Braathen B, Dunér P, Tønnessen T, Lunde IG, Sjaastad I, Brakebusch C, McCulloch AD, Gomez MF, Carlson CR, Christensen G (2020)
Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin
J Am Heart Assoc, 9 (3), e013518
DOI 10.1161/JAHA.119.013518, PubMed 32000579

Holm AM, Andreassen SL, Christensen VL, Kongerud J, Almås Ø, Auråen H, Henriksen AH, Aaberge IS, Klingenberg O, Rustøen T (2020)
Hypogammaglobulinemia and Risk of Exacerbation and Mortality in Patients with COPD
Int J Chron Obstruct Pulmon Dis, 15, 799-807
DOI 10.2147/COPD.S236656, PubMed 32368026

Holm AM, Immer F, Benden C (2020)
Lung allocation for transplant: The European perspective
Clin Transplant, e13883
DOI 10.1111/ctr.13883, PubMed 32294267

Haakensen VD, Khadse A, Sandhu V, Halvorsen AR, Solberg SK, Jørgensen LH, Brustugun OT, Kure EH, Helland Å (2020)
Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy
Int J Cancer
DOI 10.1002/ijc.33121, PubMed 32468587

Johnsen L, Hisdal J, Jonung T, Braaten A, Pedersen G (2020)
Contrast-enhanced ultrasound detects type II endoleaks during follow-up for endovascular aneurysm repair
J Vasc Surg (in press)
DOI 10.1016/j.jvs.2020.02.020, PubMed 32249048

Jönsson ÅLM, Bendstrup E, Mogensen S, Kopras EJ, McCormack FX, Campo I, Mariani F, Escribano-Montaner A, Holm AM, Martinez-Colls MDM, Pintos-Morell G, Taillé C, Crestani B, Hilberg O, Hvarregaard Christensen J, Simonsen U (2020)
Eight novel variants in the SLC34A2 gene in pulmonary alveolar microlithiasis
Eur Respir J, 55 (2)
DOI 10.1183/13993003.00806-2019, PubMed 31831582

Kaur S, Shen X, Power A, Ward ML (2020)
Stretch modulation of cardiac contractility: importance of myocyte calcium during the slow force response
Biophys Rev, 12 (1), 135-142
DOI 10.1007/s12551-020-00615-6, PubMed 31939110

Kazmi SSH, Berge ST, Sahba M, Medhus AW, Sundhagen JO (2020)
A Short Series of Laparoscopic Mesenteric Bypasses for Chronic Mesenteric Ischemia
Vasc Health Risk Manag, 16, 87-97
DOI 10.2147/VHRM.S243264, PubMed 32256075

Kierulf-Vieira KS, Sandberg CJ, Waaler J, Lund K, Skaga E, Saberniak BM, Panagopoulos I, Brandal P, Krauss S, Langmoen IA, Vik-Mo EO (2020)
A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061630, PubMed 32575464

Klaeboe LG, Brekke PH, Aaberge L, Haugaa K, Edvardsen T (2020)
Impact of transcatheter aortic valve implantation on mechanical dispersion
Open Heart, 7 (1), e001199
DOI 10.1136/openhrt-2019-001199, PubMed 32153792

Kleiven Ø, Bjørkavoll-Bergseth MF, Omland T, Aakre KM, Frøysa V, Erevik CB, Greve OJ, Melberg TH, Auestad B, Skadberg Ø, Edvardsen T, Ørn S (2020)
Endurance exercise training volume is not associated with progression of coronary artery calcification
Scand J Med Sci Sports, 30 (6), 1024-1032
DOI 10.1111/sms.13643, PubMed 32100340

Kleiven Ø, Edvardsen T, Ørn S (2020)
Echocardiography in the pre-participation evaluation of asymptomatic athletes: the never-ending story
Eur J Prev Cardiol, 2047487320932269 (in press)
DOI 10.1177/2047487320932269, PubMed 32580569

Kluge KE, Langseth MS, Opstad TB, Pettersen AÅ, Arnesen H, Tønnessen T, Seljeflot I, Helseth R (2020)
Complement Activation in Association with Markers of Neutrophil Extracellular Traps and Acute Myocardial Infarction in Stable Coronary Artery Disease
Mediators Inflamm, 2020, 5080743
DOI 10.1155/2020/5080743, PubMed 32308555

Knuuti J, Wijns W, Saraste A, Capodanno D, Barbato E, Funck-Brentano C, Prescott E, Storey RF, Deaton C, Cuisset T, Agewall S, Dickstein K, Edvardsen T, Escaned J, Gersh BJ, Svitil P, Gilard M, Hasdai D, Hatala R, Mahfoud F, Masip J, Muneretto C, Valgimigli M, Achenbach S, Bax JJ et al. (2020)
2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes
Eur Heart J, 41 (3), 407-477
DOI 10.1093/eurheartj/ehz425, PubMed 31504439

Kobirumaki-Shimozawa F, Nakanishi T, Shimozawa T, Terui T, Oyama K, Li J, Louch WE, Ishiwata S, Fukuda N (2020)
Real-Time In Vivo Imaging of Mouse Left Ventricle Reveals Fluctuating Movements of the Intercalated Discs
Nanomaterials (Basel), 10 (3)
DOI 10.3390/nano10030532, PubMed 32188039

Kristiansen O, Vethe NT, Peersen K, Fagerland MW, Sverre E, Jensen EP, Lindberg M, Gjertsen E, Gullestad L, Perk J, Dammen T, Bergan S, Husebye E, Otterstad JE, Munkhaugen J (2020)
Effect of atorvastatin on muscle symptoms in coronary heart disease patients with self-perceived statin muscle side-effects: a randomized, double blinded crossover trial
Eur Heart J Cardiovasc Pharmacother (in press)
DOI 10.1093/ehjcvp/pvaa076, PubMed 32609361

Kristiansen S, Traaen GM, Øverland B, Plagemann T, Gullestad L, Akre H, Nikolaidis K, Aakerøy L, Hunt TE, Loennechen JP, Steinshamn S, Bendz C, Anfinsen OG, Goebel V (2020)
Comparing manual and automatic scoring of sleep monitoring data from portable polygraphy
J Sleep Res, e13036
DOI 10.1111/jsr.13036, PubMed 32430962

Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
Rosuvastatin alters the genetic composition of the human gut microbiome
Sci Rep, 10 (1), 5397
DOI 10.1038/s41598-020-62261-y, PubMed 32214138

Kvåle KF, Salles S, Lervik LCN, Støylen A, Løvstakken L, Samset E, Torp H (2020)
Detection of Tissue Fibrosis using Natural Mechanical Wave Velocity Estimation: Feasibility Study
Ultrasound Med Biol (in press)
DOI 10.1016/j.ultrasmedbio.2020.04.022, PubMed 32505615

Laerum D, Brustugun OT, Gallefoss F, Falk R, Strand TE, Fjellbirkeland L (2020)
Reduced delays in diagnostic pathways for non-small cell lung cancer after local and National initiatives
Cancer Treat Res Commun, 23, 100168 (in press)
DOI 10.1016/j.ctarc.2020.100168, PubMed 32028190

Langseth MS, Helseth R, Ritschel V, Hansen CH, Andersen GØ, Eritsland J, Halvorsen S, Fagerland MW, Solheim S, Arnesen H, Seljeflot I, Opstad TB (2020)
Double-Stranded DNA and NETs Components in Relation to Clinical Outcome After ST-Elevation Myocardial Infarction
Sci Rep, 10 (1), 5007
DOI 10.1038/s41598-020-61971-7, PubMed 32193509

Larsen CK, Aalen JM, Stokke C, Fjeld JG, Kongsgaard E, Duchenne J, Degtiarova G, Gheysens O, Voigt JU, Smiseth OA, Hopp E (2020)
Regional myocardial work by cardiac magnetic resonance and non-invasive left ventricular pressure: a feasibility study in left bundle branch block
Eur Heart J Cardiovasc Imaging, 21 (2), 143-153
DOI 10.1093/ehjci/jez231, PubMed 31599327

Legøy TA, Ghila L, Vethe H, Abadpour S, Mathisen AF, Paulo JA, Scholz H, Raeder H, Chera S (2020)
In vivo hyperglycaemia exposure elicits distinct period-dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress
Acta Physiol (Oxf), 228 (4), e13433
DOI 10.1111/apha.13433, PubMed 31872528

Legøy TA, Mathisen AF, Salim Z, Vethe H, Bjørlykke Y, Abadpour S, Paulo JA, Scholz H, Ræder H, Ghila L, Chera S (2020)
In vivo Environment Swiftly Restricts Human Pancreatic Progenitors Toward Mono-Hormonal Identity via a HNF1A/HNF4A Mechanism
Front Cell Dev Biol, 8, 109
DOI 10.3389/fcell.2020.00109, PubMed 32161757

Legøy TA, Vethe H, Abadpour S, Strand BL, Scholz H, Paulo JA, Ræder H, Ghila L, Chera S (2020)
Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
Sci Rep, 10 (1), 414
DOI 10.1038/s41598-019-57305-x, PubMed 31942009

Lieve KVV, Dusi V, van der Werf C, Bos JM, Lane CM, Stokke MK, Roston TM, Djupsjöbacka A, Wada Y, Denjoy I, Bundgaard H, Noguer FRI, Semsarian C, Robyns T, Hofman N, Tanck MW, van den Berg MP, Kammeraad JAE, Krahn AD, Clur SB, Sacher F, Till J, Skinner JR, Tfelt-Hansen J, Probst V et al. (2020)
Heart Rate Recovery After Exercise Is Associated With Arrhythmic Events in Patients With Catecholaminergic Polymorphic Ventricular Tachycardia
Circ Arrhythm Electrophysiol, 13 (3), e007471
DOI 10.1161/CIRCEP.119.007471, PubMed 32063070

Magne J, Bharucha T, Cikes M, Galderisi M, Price S, Sade LE, Popescu BA, Cosyns B, Edvardsen T (2020)
EuroEcho 2019: highlights
Eur Heart J Cardiovasc Imaging, 21 (5), 469-478
DOI 10.1093/ehjci/jeaa037, PubMed 32182333

Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
Low fibre intake is associated with gut microbiota alterations in chronic heart failure
ESC Heart Fail, 7 (2), 456-466
DOI 10.1002/ehf2.12596, PubMed 31978943

Michalski B, Dweck MR, Marsan NA, Cameli M, D'Andrea A, Carvalho RF, Holte E, Robert TP, Haugaa KH (2020)
The evaluation of aortic stenosis, how the new guidelines are implemented across Europe: a survey by EACVI
Eur Heart J Cardiovasc Imaging, 21 (4), 357-362
DOI 10.1093/ehjci/jeaa009, PubMed 32196100

Mohammadzadeh N, Melleby AO, Palmero S, Sjaastad I, Chakravarti S, Engebretsen KVT, Christensen G, Lunde IG, Tønnessen T (2020)
Moderate Loss of the Extracellular Matrix Proteoglycan Lumican Attenuates Cardiac Fibrosis in Mice Subjected to Pressure Overload
Cardiology, 145 (3), 187-198
DOI 10.1159/000505318, PubMed 31968347

Morrison-Beedy D, Jenssen U, Bochenek J, Bowles W, King TS, Mathisen L (2020)
Building Global Nursing Citizens Through Curricular Integration of Sustainable Development Goals Within an International Clinical Experience
Nurse Educ (in press)
DOI 10.1097/NNE.0000000000000831, PubMed 32195766

Mustafa T, Wergeland I, Baba K, Pathak S, Hoosen AA, Dyrhol-Riise AM (2020)
Mycobacterial antigens in pleural fluid mononuclear cells to diagnose pleural tuberculosis in HIV co-infected patients
BMC Infect Dis, 20 (1), 459
DOI 10.1186/s12879-020-05165-6, PubMed 32611401

Muthiah A, Beitnes JO, Skulstad H (2020)
Patients with infective endocarditis referred to Division of Cardiovascular and Pulmonary Diseases at Oslo University Hospital between 2014 and 2017
Scand Cardiovasc J
DOI 10.1080/14017431.2020.1734232, PubMed 32157906

Nakstad ER, Stær-Jensen H, Wimmer H, Henriksen J, Alteheld LH, Reichenbach A, Drægni T, Šaltytė-Benth J, Wilson JA, Etholm L, Øijordsbakken M, Eritsland J, Seljeflot I, Jacobsen D, Andersen GØ, Lundqvist C, Sunde K (2020)
Late awakening, prognostic factors and long-term outcome in out-of-hospital cardiac arrest - results of the prospective Norwegian Cardio-Respiratory Arrest Study (NORCAST)
Resuscitation, 149, 170-179
DOI 10.1016/j.resuscitation.2019.12.031, PubMed 31926258

Nelson LM, Andreassen AK, Arora S, Andersson B, Gude E, Eiskjaer H, Rådegran G, Dellgren G, Gullestad L, Gustafsson F (2020)
Mild acute cellular rejection and development of cardiac allograft vasculopathy assessed by intravascular ultrasound and coronary angiography in heart transplant recipients-a SCHEDULE trial substudy
Transpl Int, 33 (5), 517-528
DOI 10.1111/tri.13577, PubMed 31958178

Norekvål TM, Allore HG, Bendz B, Bjorvatn C, Borregaard B, Brørs G, Deaton C, Fålun N, Hadjistavropoulos H, Hansen TB, Igland S, Larsen AI, Palm P, Pettersen TR, Rasmussen TB, Schjøtt J, Søgaard R, Valaker I, Zwisler AD, Rotevatn S, CONCARD Investigators (2020)
Rethinking rehabilitation after percutaneous coronary intervention: a protocol of a multicentre cohort study on continuity of care, health literacy, adherence and costs at all care levels (the CONCARDPCI)
BMJ Open, 10 (2), e031995
DOI 10.1136/bmjopen-2019-031995, PubMed 32054625

Norum IB, Edvardsen T, Ruddox V, Gunther A, Dahle G, Otterstad JE (2020)
Three-dimensional versus two-dimensional transthoracic echocardiography for left ventricular outflow tract measurements in severe aortic stenosis. A cross-sectional study using computer tomography and Haegar sizers as reference
Scand Cardiovasc J
DOI 10.1080/14017431.2020.1761559, PubMed 32408833

Noureddine FY, Altara R, Fan F, Yabluchanskiy A, Booz GW, Zouein FA (2020)
Impact of the Renin-Angiotensin System on the Endothelium in Vascular Dementia: Unresolved Issues and Future Perspectives
Int J Mol Sci, 21 (12)
DOI 10.3390/ijms21124268, PubMed 32560034

Nytrøen K, Rolid K, Yardley M, Gullestad L (2020)
Effect of high-intensity interval training in young heart transplant recipients: results from two randomized controlled trials
BMC Sports Sci Med Rehabil, 12, 35
DOI 10.1186/s13102-020-00180-1, PubMed 32518655

Okin PM, Hille DA, Wachtell K, Kjeldsen SE, Julius S, Devereux RB (2020)
On-treatment HDL cholesterol predicts incident atrial fibrillation in hypertensive patients with left ventricular hypertrophy
Blood Press, 1-8 (in press)
DOI 10.1080/08037051.2020.1782171, PubMed 32586143

Otterstad JE, Norum IB, Ruddox V, Bendz B, Haugaa KH, Edvardsen T (2020)
The impact of semi-automatic versus manually adjusted assessment of global longitudinal strain in post-myocardial infarction patients
Int J Cardiovasc Imaging, 36 (7), 1283-1290
DOI 10.1007/s10554-020-01826-4, PubMed 32236908

Peersen K, Otterstad JE, Sverre E, Perk J, Gullestad L, Moum T, Dammen T, Munkhaugen J (2020)
Medical and Psychosocial Factors Associated With Low Physical Activity and Increasing Exercise Level After a Coronary Event
J Cardiopulm Rehabil Prev, 40 (1), 35-40
DOI 10.1097/HCR.0000000000000399, PubMed 30720643

Perdreau-Dahl H, Progida C, Barfeld SJ, Guldsten H, Thiede B, Arntzen M, Bakke O, Mills IG, Krauss S, Morth JP (2020)
Sjögren syndrome/scleroderma autoantigen 1 is a direct Tankyrase binding partner in cancer cells
Commun Biol, 3 (1), 123
DOI 10.1038/s42003-020-0851-2, PubMed 32170109

Pettersen EM, Avdal J, Hisdal J, Torp H, Seternes A (2020)
Validation of a novel ultrasound Doppler monitoring device (earlybird) for detection of microvascular circulatory changes
Clin Hemorheol Microcirc, 74 (4), 429-440
DOI 10.3233/CH-190707, PubMed 31743988

Pezel T, Coisne A, Mahmoud-Elsayed H, Mandoli GE, Elgamal SM, Podlesnikar T, Cameli M, Grapsa J, Lafitte S, Edvardsen T, Donal E, Dreyfus J (2020)
EACVI communication paper: first international young dedicated multimodal cardiovascular imaging simulation education event organized by the ESC
Eur Heart J Cardiovasc Imaging, 21 (2), 124-126
DOI 10.1093/ehjci/jez299, PubMed 31834376

Rodriguez-Palomares JF, Edvardsen T, Almeida AG, Petersen SE (2020)
EuroCMR 2019 highlights
Eur Heart J Cardiovasc Imaging, 21 (2), 127-131
DOI 10.1093/ehjci/jez307, PubMed 31821461

Rolid K, Andreassen AK, Yardley M, Gude E, Bjørkelund E, Authen AR, Grov I, Broch K, Gullestad L, Nytrøen K (2020)
Long-term effects of high-intensity training vs moderate intensity training in heart transplant recipients: A 3-year follow-up study of the randomized-controlled HITTS study
Am J Transplant (in press)
DOI 10.1111/ajt.16087, PubMed 32484261

Ross S, Nestaas E, Kongsgaard E, Odland HH, Haland TF, Hopp E, Haugaa KH, Edvardsen T (2020)
Septal contraction predicts acute haemodynamic improvement and paced QRS width reduction in cardiac resynchronization therapy
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jez315, PubMed 31925420

Rutherford OW, Jonasson C, Ghanima W, Söderdahl F, Halvorsen S (2020)
Comparison of dabigatran, rivaroxaban, and apixaban for effectiveness and safety in atrial fibrillation: a nationwide cohort study
Eur Heart J Cardiovasc Pharmacother, 6 (2), 75-85
DOI 10.1093/ehjcvp/pvz086, PubMed 31942972

Schalit I, Espinoza A, Pettersen FJ, Snartland S, Ringdal ML, Hoel TN, Skulstad H, Fosse E, Fiane AE, Halvorsen PS (2020)
Detection of Thromboembolic Events and Pump Thrombosis in HeartWare HVAD Using Accelerometer in a Porcine Model
ASAIO J, 66 (1), 38-48
DOI 10.1097/MAT.0000000000000954, PubMed 30688692

Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC (2020)
Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
Biochem Biophys Res Commun, 523 (4), 867-873
DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888

Skattebo Ø, Bjerring AW, Auensen M, Sarvari SI, Cumming KT, Capelli C, Hallén J (2020)
Blood volume expansion does not explain the increase in peak oxygen uptake induced by 10 weeks of endurance training
Eur J Appl Physiol, 120 (5), 985-999
DOI 10.1007/s00421-020-04336-2, PubMed 32172291

Skjølsvik ET, Hasselberg NE, Dejgaard LA, Lie ØH, Andersen K, Holm T, Edvardsen T, Haugaa KH (2020)
Exercise is Associated With Impaired Left Ventricular Systolic Function in Patients With Lamin A/C Genotype
J Am Heart Assoc, 9 (2), e012937
DOI 10.1161/JAHA.119.012937, PubMed 31957533

Skogestad J, Aronsen JM, Tovsrud N, Wanichawan P, Hougen K, Stokke MK, Carlson CR, Sjaastad I, Sejersted OM, Swift F (2020)
Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes
Cardiovasc Res, 116 (1), 78-90
DOI 10.1093/cvr/cvz087, PubMed 30949686

Skulstad H, Cosyns B, Popescu BA, Galderisi M, Salvo GD, Donal E, Petersen S, Gimelli A, Haugaa KH, Muraru D, Almeida AG, Schulz-Menger J, Dweck MR, Pontone G, Sade LE, Gerber B, Maurovich-Horvat P, Bharucha T, Cameli M, Magne J, Westwood M, Maurer G, Edvardsen T (2020)
COVID-19 pandemic and cardiac imaging: EACVI recommendations on precautions, indications, prioritization, and protection for patients and healthcare personnel
Eur Heart J Cardiovasc Imaging, 21 (6), 592-598
DOI 10.1093/ehjci/jeaa072, PubMed 32242891

Smistad E, Ostvik A, Salte IM, Melichova D, Nguyen TM, Haugaa K, Brunvand H, Edvardsen T, Leclerc S, Bernard O, Grenne B, Lovstakken L (2020)
Real-time automatic ejection fraction and foreshortening detection using deep learning
IEEE Trans Ultrason Ferroelectr Freq Control (in press)
DOI 10.1109/TUFFC.2020.2981037, PubMed 32175861

Soyseth TS, Dew MA, Lund MB, Haugstad GK, Soyseth V, Malt UF (2020)
Coping Patterns and Emotional Distress in Patients With Chronic Obstructive Lung Disease Who Are Undergoing Lung Transplant Evaluation
Prog Transplant, 1526924820933817 (in press)
DOI 10.1177/1526924820933817, PubMed 32578510

Stankovic B, Aamodt H, Bjørhovde HAK, Müller E, Hammarström C, Brustugun OT, Helland Å, Øynebråten I, Corthay A (2020)
The immune microenvironment in typical carcinoid lung tumour, a brief report of four cases
Scand J Immunol, e12893
DOI 10.1111/sji.12893, PubMed 32433774

Stankovic I, Dweck MR, Marsan NA, Bergler-Klein J, Holte E, Manka R, Schulz-Menger J, Sitges M, Haugaa KH (2020)
The EACVI survey on cardiac imaging in cardio-oncology
Eur Heart J Cardiovasc Imaging (in press)
DOI 10.1093/ehjci/jeaa111, PubMed 32464650

Stankovic I, Stefanovic M, Prinz C, Ciarka A, Daraban AM, Kotrc M, Aarones M, Szulik M, Winter S, Kukulski T, Aakhus S, Willems R, Fehske W, Penicka M, Faber L, Neskovic AN, Voigt JU (2020)
The association of mechanical dyssynchrony and resynchronization therapy with survival in heart failure with a wide QRS complex: a two-world study
Int J Cardiovasc Imaging
DOI 10.1007/s10554-020-01865-x, PubMed 32356183

Stensrud T, Rossvoll Ø, Mathiassen M, Melau J, Illidi C, Østgaard HN, Hisdal J, Stang J (2020)
Lung function and oxygen saturation after participation in Norseman Xtreme Triathlon
Scand J Med Sci Sports, 30 (6), 1008-1016
DOI 10.1111/sms.13651, PubMed 32153035

Stienen S, Ferreira JP, Kobayashi M, Preud'homme G, Dobre D, Machu JL, Duarte K, Bresso E, Devignes MD, López N, Girerd N, Aakhus S, Ambrosio G, Brunner-La Rocca HP, Fontes-Carvalho R, Fraser AG, van Heerebeek L, Heymans S, de Keulenaer G, Marino P, McDonald K, Mebazaa A, Papp Z, Raddino R, Tschöpe C et al. (2020)
Enhanced clinical phenotyping by mechanistic bioprofiling in heart failure with preserved ejection fraction: insights from the MEDIA-DHF study (The Metabolic Road to Diastolic Heart Failure)
Biomarkers, 25 (2), 201-211
DOI 10.1080/1354750X.2020.1727015, PubMed 32063068

Stokke MK, Castrini AI, Aneq MÅ, Jensen HK, Madsen T, Hansen J, Bundgaard H, Gilljam T, Platonov PG, Svendsen JH, Edvardsen T, Haugaa KH (2020)
Absence of ECG Task Force Criteria does not rule out structural changes in genotype positive ARVC patients
Int J Cardiol (in press)
DOI 10.1016/j.ijcard.2020.05.095, PubMed 32504717

Storsten P, Aalen JM, Boe E, Remme EW, Gjesdal O, Larsen CK, Andersen ØS, Eriksen M, Kongsgaard E, Duchenne J, Voigt JU, Smiseth OA, Skulstad H (2020)
Mechanical Effects on Right Ventricular Function From Left Bundle Branch Block and Cardiac Resynchronization Therapy
JACC Cardiovasc Imaging (in press)
DOI 10.1016/j.jcmg.2019.11.016, PubMed 31954643

Sverre E, Peersen K, Weedon-Fekjær H, Perk J, Gjertsen E, Husebye E, Gullestad L, Dammen T, Otterstad JE, Munkhaugen J (2020)
Preventable clinical and psychosocial factors predicted two out of three recurrent cardiovascular events in a coronary population
BMC Cardiovasc Disord, 20 (1), 61
DOI 10.1186/s12872-020-01368-6, PubMed 32024471

Tazmini K, Frisk M, Lewalle A, Laasmaa M, Morotti S, Lipsett DB, Manfra O, Skogested J, Aronsen JM, Sejersted OM, Sjaastad I, Edwards AG, Grandi E, Niederer SA, Øie E, Louch WE (2020)
Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes
Circ Res, 126 (7), 889-906
DOI 10.1161/CIRCRESAHA.119.315641, PubMed 32070187

Thøgersen H, Møller B, Åsli LM, Bhargava S, Kvåle R, Fjellbirkeland L, Robsahm TE, Aaserud S, Babigumira R, Larsen IK (2020)
Waiting times and treatment following cancer diagnosis: comparison between immigrants and the Norwegian host population
Acta Oncol, 59 (4), 376-383
DOI 10.1080/0284186X.2019.1711167, PubMed 31920119

Trøseid M, Andersen GØ, Broch K, Hov JR (2020)
The gut microbiome in coronary artery disease and heart failure: Current knowledge and future directions
EBioMedicine, 52, 102649
DOI 10.1016/j.ebiom.2020.102649, PubMed 32062353

Tønnessen E, Hisdal J, Ronnestad BR (2020)
Influence of Interval Training Frequency on Time-Trial Performance in Elite Endurance Athletes
Int J Environ Res Public Health, 17 (9)
DOI 10.3390/ijerph17093190, PubMed 32375328

Törnudd M, Ramström S, Kvitting JE, Alfredsson J, Pihl R, Berg S (2020)
Protamine stimulates platelet aggregation in vitro with activation of the fibrinogen receptor and alpha-granule release, but impairs secondary activation via ADP and thrombin receptors
Platelets
DOI 10.1080/09537104.2020.1719992, PubMed 31992110

Ulvestad B, Ulvestad M, Skaugset NP, Aaløkken TM, Günther A, Clemm T, Lund MB, Ellingsen DG (2020)
Pulmonary function and high-resolution computed tomography in outdoor rock drillers exposed to crystalline silica
Occup Environ Med (in press)
DOI 10.1136/oemed-2019-106254, PubMed 32571792

Ulvestad M, Durheim MT, Kongerud JS, Hansen BH, Lund MB, Edvardsen E (2020)
Cardiorespiratory Fitness and Physical Activity following Lung Transplantation: A National Cohort Study
Respiration, 99 (4), 316-324
DOI 10.1159/000506883, PubMed 32272479

Voigt JU, Mălăescu GG, Haugaa K, Badano L (2020)
How to do LA strain
Eur Heart J Cardiovasc Imaging, 21 (7), 715-717
DOI 10.1093/ehjci/jeaa091, PubMed 32548623

Willeit P, Tschiderer L, Allara E, Reuber K, Seekircher L, Gao L, Liao X, Lonn E, Gerstein HC, Yusuf S, Brouwers FP, Asselbergs FW, van Gilst W, Anderssen SA, Grobbee DE, Kastelein JJP, Visseren FLJ, Ntaios G, Hatzitolios AI, Savopoulos C, Nieuwkerk PT, Stroes E, Walters M, Higgins P, Dawson J et al. (2020)
Carotid Intima-Media Thickness Progression as Surrogate Marker for Cardiovascular Risk: Meta-Analysis of 119 Clinical Trials Involving 100,667 Patients
Circulation (in press)
DOI 10.1161/CIRCULATIONAHA.120.046361, PubMed 32546049

Zimpfer D, Fiane AE, Larbalestier R, Tsui S, Jansz P, Simon A, Schueler S, Strueber M, Schmitto JD (2020)
Long-Term Survival of Patients With Advanced Heart Failure Receiving an Left Ventricular Assist Device Intended as a Bridge to Transplantation: The Registry to Evaluate the HeartWare Left Ventricular Assist System
Circ Heart Fail, 13 (3), e006252
DOI 10.1161/CIRCHEARTFAILURE.119.006252, PubMed 32164438

Aamodt IT, Lycholip E, Celutkiene J, von Lueder T, Atar D, Falk RS, Hellesø R, Jaarsma T, Strömberg A, Lie I (2020)
Self-Care Monitoring of Heart Failure Symptoms and Lung Impedance at Home Following Hospital Discharge: Longitudinal Study
J Med Internet Res, 22 (1), e15445
DOI 10.2196/15445, PubMed 31909717

 
Page visits: 409532