Biomedical research at Oslo University Hospital

Oslo University Hospital is a merger of three former university hospitals in Oslo. Biomedical research is one of the hospital's core activities. Research at the hospital is closely interlinked with research undertaken at the University of Oslo. More than 50% of all biomedical research in Norway is published by researchers affiliated with the hospital. Research undertaken cover both basic research, translational research, and clinical research.

Oslo University Hospital has a central role in developing and supporting biomedical research within the South-Eastern Regional Health Authority. The hospital also pursues international research collaborations.

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Summary of publications:

Publications (original articles or review articles) published in 2019 from OUS - Division of Clinical Neuroscience

53 publications found

Almekhlafi MA, Kunz WG, Menon BK, McTaggart RA, Jayaraman MV, Baxter BW, Heck D, Frei D, Derdeyn CP, Takagi T, Aamodt AH, Fragata IMR, Hill MD, Demchuk AM, Goyal M (2019)
Imaging of Patients with Suspected Large-Vessel Occlusion at Primary Stroke Centers: Available Modalities and a Suggested Approach
AJNR Am J Neuroradiol, 40 (3), 396-400
DOI 10.3174/ajnr.A5971, PubMed 30705072

Arntzen C, Sveen U, Hagby C, Bonsaksen T, Dolva AS, Horghagen S (2019)
Community-based occupational therapy in Norway: Content, dilemmas, and priorities
Scand J Occup Ther, 1-11 (in press)
DOI 10.1080/11038128.2018.1548647, PubMed 30632858

Austevoll IM, Gjestad R, Grotle M, Solberg T, Brox JI, Hermansen E, Rekeland F, Indrekvam K, Storheim K, Hellum C (2019)
Follow-up score, change score or percentage change score for determining clinical important outcome following surgery? An observational study from the Norwegian registry for Spine surgery evaluating patient reported outcome measures in lumbar spinal stenosis and lumbar degenerative spondylolisthesis
BMC Musculoskelet Disord, 20 (1), 31
DOI 10.1186/s12891-018-2386-y, PubMed 30658613

Austevoll IM, Hermansen E, Fagerland M, Rekeland F, Solberg T, Storheim K, Brox JI, Lønne G, Indrekvam K, Aaen J, Grundnes O, Hellum C (2019)
Decompression alone versus decompression with instrumental fusion the NORDSTEN degenerative spondylolisthesis trial (NORDSTEN-DS); study protocol for a randomized controlled trial
BMC Musculoskelet Disord, 20 (1), 7
DOI 10.1186/s12891-018-2384-0, PubMed 30611229

Bains SJ, Niehusmann PF, Meling TR, Saxhaug C, Züchner M, Brandal P (2019)
Disseminated central nervous system hemangioblastoma in a patient with no clinical or genetic evidence of von Hippel-Lindau disease-a case report and literature review
Acta Neurochir (Wien), 161 (2), 343-349
DOI 10.1007/s00701-019-03800-z, PubMed 30652202

Bandres-Ciga S, Saez-Atienzar S, Bonet-Ponce L, Billingsley K, Vitale D, Blauwendraat C, Gibbs JR, Pihlstrøm L, Gan-Or Z, International Parkinson's Disease Genomics Consortium (IPDGC), Cookson MR, Nalls MA, Singleton AB (2019)
The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease
Mov Disord (in press)
DOI 10.1002/mds.27614, PubMed 30675927

Bendtsen L, Zakrzewska JM, Abbott J, Braschinsky M, Di Stefano G, Donnet A, Eide PK, Leal PRL, Maarbjerg S, May A, Nurmikko T, Obermann M, Jensen TS, Cruccu G (2019)
EAN guideline on trigeminal neuralgia
Eur J Neurol (in press)
DOI 10.1111/ene.13950, PubMed 30860637

Berg L, Thoresen H, Neckelmann G, Furunes H, Hellum C, Espeland A (2019)
Facet arthropathy evaluation: CT or MRI?
Eur Radiol (in press)
DOI 10.1007/s00330-019-06047-5, PubMed 30796571

Bragstad LK, Bronken BA, Sveen U, Hjelle EG, Kitzmüller G, Martinsen R, Kvigne KJ, Mangset M, Kirkevold M (2019)
Implementation fidelity in a complex intervention promoting psychosocial well-being following stroke: an explanatory sequential mixed methods study
BMC Med Res Methodol, 19 (1), 59
DOI 10.1186/s12874-019-0694-z, PubMed 30876403

Burns ML, Nikanorova M, Baftiu A, Rasmussen JB, Johannessen SI, Landmark CJ (2019)
Pharmacokinetic variability and clinical use of lacosamide in children and adolescents in Denmark and Norway
Ther Drug Monit (in press)
DOI 10.1097/FTD.0000000000000599, PubMed 30688870

Bøen E, Hjørnevik T, Hummelen B, Elvsåshagen T, Moberget T, Holtedahl JE, Babovic A, Hol PK, Karterud S, Malt UF (2019)
Patterns of altered regional brain glucose metabolism in borderline personality disorder and bipolar II disorder
Acta Psychiatr Scand, 139 (3), 256-268
DOI 10.1111/acps.12997, PubMed 30552759

Børte S, Zwart JA, Stensland SØ, Hagen K, Winsvold BS (2019)
Parental migraine in relation to migraine in offspring: Family linkage analyses from the HUNT Study
Cephalalgia, 333102419828989 (in press)
DOI 10.1177/0333102419828989, PubMed 30714392

Corniola MV, Lemée JM, Da Broi M, Joswig H, Schaller K, Helseth E, Meling TR (2019)
Posterior fossa meningiomas: perioperative predictors of extent of resection, overall survival and progression-free survival
Acta Neurochir (Wien) (in press)
DOI 10.1007/s00701-019-03862-z, PubMed 30859321

Eikeseth FF, Denninghaus S, Cropley M, Witthöft M, Pawelzik M, Sütterlin S (2019)
The cortisol awakening response at admission to hospital predicts depression severity after discharge in MDD patients
J Psychiatr Res, 111, 44-50 (in press)
DOI 10.1016/j.jpsychires.2019.01.002, PubMed 30669031

Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Christensen JH, Churchhouse C, Dellenvall K, Demontis D, De Rubeis S, Devlin B, Djurovic S et al. (2019)
Identification of common genetic risk variants for autism spectrum disorder
Nat Genet, 51 (3), 431-444
DOI 10.1038/s41588-019-0344-8, PubMed 30804558

Grøvle L, Fjeld OR, Haugen AJ, Helgeland J, Småstuen MC, Solberg TK, Zwart JA, Grotle M (2019)
The Rates of LSS Surgery in Norwegian Public Hospitals: A Threefold Increase From 1999 to 2013
Spine (Phila Pa 1976), 44 (6), E372-E378
DOI 10.1097/BRS.0000000000002858, PubMed 30234811

Hagberg G, Fure B, Sandset EC, Thommessen B, Ihle-Hansen H, Øksengård AR, Nygård S, Wyller TB, Ihle-Hansen H (2019)
Long-term effects on survival after a 1-year multifactorial vascular risk factor intervention after stroke or TIA: secondary analysis of a randomized controlled trial, a 7-year follow-up study
Vasc Health Risk Manag, 15, 11-18
DOI 10.2147/VHRM.S191873, PubMed 30799926

Hagen K, Hopstock LA, Elise Eggen A, Mathiesen EB, Nilsen KB (2019)
Does insomnia modify the association between C-reactive protein and migraine? The Tromsø Study 2015-2016
Cephalalgia, 333102418825370 (in press)
DOI 10.1177/0333102418825370, PubMed 30862180

Hermansen E, Myklebust TÅ, Austevoll IM, Rekeland F, Solberg T, Storheim K, Grundnes O, Aaen J, Brox JI, Hellum C, Indrekvam K (2019)
Clinical outcome after surgery for lumbar spinal stenosis in patients with insignificant lower extremity pain. A prospective cohort study from the Norwegian registry for spine surgery
BMC Musculoskelet Disord, 20 (1), 36
DOI 10.1186/s12891-019-2407-5, PubMed 30669998

Hesla Nordstrand SE, Hansen BH, Rootwelt T, Karlsen TI, Swanson D, Nilsen KB, Knudsen S (2019)
Psychiatric symptoms in patients with post-H1N1 narcolepsy type 1 in Norway
Sleep (in press)
DOI 10.1093/sleep/zsz008, PubMed 30649483

Holmøy AKT, Johannessen CH, Hope S, van Walsem MR, Aanonsen NO, Hassel B (2019)
Uncovering health and social care needs among myotonic dystrophy patients
Acta Neurol Scand (in press)
DOI 10.1111/ane.13086, PubMed 30848487

Holthe OO, Hellstrom T, Andelic N, Server A, Sigurdardottir S (2019)
Improvement and Prediction of Memory and Executive Functions in Patients Admitted to a Neurosurgery Service With Complicated and Uncomplicated Mild Traumatic Brain Injury
J Head Trauma Rehabil (in press)
DOI 10.1097/HTR.0000000000000463, PubMed 30829814

Iqbal Z, Tawamie H, Ba W, Reis A, Halak BA, Sticht H, Uebe S, Kasri NN, Riazuddin S, van Bokhoven H, Abou Jamra R (2019)
Loss of function of SVBP leads to autosomal recessive intellectual disability, microcephaly, ataxia, and hypotonia
Genet Med (in press)
DOI 10.1038/s41436-018-0415-8, PubMed 30607023

Jansen IE, Savage JE, Watanabe K, Bryois J, Williams DM, Steinberg S, Sealock J, Karlsson IK, Hägg S, Athanasiu L, Voyle N, Proitsi P, Witoelar A, Stringer S, Aarsland D, Almdahl IS, Andersen F, Bergh S, Bettella F, Bjornsson S, Brækhus A, Bråthen G, de Leeuw C, Desikan RS, Djurovic S et al. (2019)
Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 51 (3), 404-413
DOI 10.1038/s41588-018-0311-9, PubMed 30617256

Jusufovic M, Skagen K, Krohg-Sørensen K, Skjelland M (2019)
Current medical and surgical stroke prevention therapies for patients with carotid artery stenosis
Curr Neurovasc Res (in press)
DOI 10.2174/1567202616666190131162811, PubMed 30706783

Kitzmüller G, Mangset M, Evju AS, Angel S, Aadal L, Martinsen R, Bronken BA, Kvigne K, Bragstad LK, Hjelle EG, Sveen U, Kirkevold M (2019)
Finding the Way Forward: The Lived Experience of People With Stroke After Participation in a Complex Psychosocial Intervention
Qual Health Res, 1049732319833366 (in press)
DOI 10.1177/1049732319833366, PubMed 30862270

Kristoffersen ES, Winsvold BS, Faiz KW (2019)
Prestige of neurological disorders among future neurologists in Norway
Acta Neurol Scand (in press)
DOI 10.1111/ane.13087, PubMed 30851195

Lane JM, Jones SE, Dashti HS, Wood AR, Aragam KG, van Hees VT, Strand LB, Winsvold BS, Wang H, Bowden J, Song Y, Patel K, Anderson SG, Beaumont RN, Bechtold DA, Cade BE, Haas M, Kathiresan S, Little MA, Luik AI, Loudon AS, Purcell S, Richmond RC, Scheer FAJL, Schormair B et al. (2019)
Biological and clinical insights from genetics of insomnia symptoms
Nat Genet, 51 (3), 387-393
DOI 10.1038/s41588-019-0361-7, PubMed 30804566

Larsen Burns M, Kinge E, Stokke Opdal M, Johannessen SI, Johannessen Landmark C (2019)
Therapeutic drug monitoring of gabapentin in various indications
Acta Neurol Scand (in press)
DOI 10.1111/ane.13075, PubMed 30710348

Latysheva A, Emblem KE, Brandal P, Vik-Mo EO, Pahnke J, Røysland K, Hald JK, Server A (2019)
Dynamic susceptibility contrast and diffusion MR imaging identify oligodendroglioma as defined by the 2016 WHO classification for brain tumors: histogram analysis approach
Neuroradiology (in press)
DOI 10.1007/s00234-019-02173-5, PubMed 30712139

Liu M, Jiang Y, Wedow R, Li Y, Brazel DM, Chen F, Datta G, Davila-Velderrain J, McGuire D, Tian C, Zhan X, 23andMe Research Team, HUNT All-In Psychiatry, Choquet H, Docherty AR, Faul JD, Foerster JR, Fritsche LG, Gabrielsen ME, Gordon SD, Haessler J, Hottenga JJ, Huang H, Jang SK, Jansen PR et al. (2019)
Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use
Nat Genet, 51 (2), 237-244
DOI 10.1038/s41588-018-0307-5, PubMed 30643251

Meents JE, Bressan E, Sontag S, Foerster A, Hautvast P, Rösseler C, Hampl M, Schüler H, Goetzke R, Chi Le TK, Kleggetveit IP, Le Cann K, Kerth C, Rush AM, Rogers M, Kohl Z, Schmelz M, Wagner W, Jørum E, Namer B, Winner B, Zenke M, Lampert A (2019)
The role of Nav1.7 in human nociceptors: insights from human iPS cell-derived sensory neurons of erythromelalgia patients
Pain (in press)
DOI 10.1097/j.pain.0000000000001511, PubMed 30720580

Meling TR, Da Broi M, Scheie D, Helseth E, Smoll NR (2019)
Meningioma Surgery-Are We Making Progress?
World Neurosurg (in press)
DOI 10.1016/j.wneu.2019.01.042, PubMed 30684722

Mouthaan BE, Rados M, Boon P, Carrette E, Diehl B, Jung J, Kimiskidis V, Kobulashvili T, Kuchukhidze G, Larsson PG, Leitinger M, Ryvlin P, Rugg-Gunn F, Seeck M, Vulliémoz S, Huiskamp G, Leijten FSS, Van Eijsden P, Trinka E, Braun KPJ, E-PILEPSY consortium (2019)
Diagnostic accuracy of interictal source imaging in presurgical epilepsy evaluation: A systematic review from the E-PILEPSY consortium
Clin Neurophysiol (in press)
DOI 10.1016/j.clinph.2018.12.016, PubMed 30824202

Mäki-Marttunen T, Krull F, Bettella F, Hagen E, Næss S, Ness TV, Moberget T, Elvsåshagen T, Metzner C, Devor A, Edwards AG, Fyhn M, Djurovic S, Dale AM, Andreassen OA, Einevoll GT (2019)
Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations
Cereb Cortex, 29 (2), 875-891
DOI 10.1093/cercor/bhy291, PubMed 30475994

Plans D, Morelli D, Sütterlin S, Ollis L, Derbyshire G, Cropley M (2019)
Use of a Biofeedback Breathing App to Augment Poststress Physiological Recovery: Randomized Pilot Study
JMIR Form Res, 3 (1), e12227
DOI 10.2196/12227, PubMed 30684437

Quist-Paulsen E, Kran AB, Lindland ES, Ellefsen K, Sandvik L, Dunlop O, Ormaasen V (2019)
To what extent can clinical characteristics be used to distinguish encephalitis from encephalopathy of other causes? Results from a prospective observational study
BMC Infect Dis, 19 (1), 80
DOI 10.1186/s12879-018-3570-2, PubMed 30669985

Rosic B, Dukefoss DB, Åbjørsbråten KS, Tang W, Jensen V, Ottersen OP, Enger R, Nagelhus EA (2019)
Aquaporin-4-independent volume dynamics of astroglial endfeet during cortical spreading depression
Glia (in press)
DOI 10.1002/glia.23604, PubMed 30791140

Rydning SL, Koht J, Sheng Y, Sowa P, Hjorthaug HS, Wedding IM, Erichsen AK, Hovden IA, Backe PH, Tallaksen CME, Vigeland MD, Selmer KK (2019)
Biallelic POLR3A variants confirmed as a frequent cause of hereditary ataxia and spastic paraparesis
Brain (in press)
DOI 10.1093/brain/awz041, PubMed 30847471

Rødevand L, Steen NE, Elvsåshagen T, Quintana DS, Reponen EJ, Mørch RH, Lunding SH, Vedal TSJ, Dieset I, Melle I, Lagerberg TV, Andreassen OA (2019)
Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade
Acta Psychiatr Scand (in press)
DOI 10.1111/acps.13008, PubMed 30697685

Rønning OM, Logallo N, Thommessen B, Tobro H, Novotny V, Kvistad CE, Aamodt AH, Næss H, Waje-Andreassen U, Thomassen L (2019)
Tenecteplase Versus Alteplase Between 3 and 4.5 Hours in Low National Institutes of Health Stroke Scale
Stroke, 50 (2), 498-500
DOI 10.1161/STROKEAHA.118.024223, PubMed 30602354

Sabir MS, Blauwendraat C, Ahmed S, Serrano GE, Beach TG, Perkins M, Rice AC, Masliah E, Morris CM, Pihlstrom L, Pantelyat A, Resnick SM, Cookson MR, Hernandez DG, Albert M, Dawson TM, Rosenthal LS, Houlden H, Pletnikova O, Troncoso J, Scholz SW (2019)
Assessment of APOE in atypical parkinsonism syndromes
Neurobiol Dis, 127, 142-146 (in press)
DOI 10.1016/j.nbd.2019.02.016, PubMed 30798004

Skagen K, Hetlevik SO, Zamani M, Lilleby V, Skjelland M (2019)
Preclinical Carotid Atherosclerosis in Patients With Juvenile-Onset Mixed Connective Tissue Disease
J Stroke Cerebrovasc Dis (in press)
DOI 10.1016/j.jstrokecerebrovasdis.2019.01.027, PubMed 30772156

Skodvin TØ, Evju Ø, Sorteberg A, Isaksen JG (2019)
Prerupture Intracranial Aneurysm Morphology in Predicting Risk of Rupture: A Matched Case-Control Study
Neurosurgery, 84 (1), 132-140
DOI 10.1093/neuros/nyy010, PubMed 29529238

Systad S, Bjornvold M, Sorensen C, Lyster SAH (2019)
The Value of Electroencephalogram in Assessing Children With Speech and Language Impairments
J. Speech Lang. Hear. Res., 62 (1), 153-168

Syvertsen M, Selmer K, Enger U, Nakken KO, Pal DK, Smith A, Koht J (2019)
Psychosocial complications in juvenile myoclonic epilepsy
Epilepsy Behav, 90, 122-128
DOI 10.1016/j.yebeh.2018.11.022, PubMed 30530133

Vandvik PO, Lähdeoja T, Ardern C, Buchbinder R, Moro J, Brox JI, Burgers J, Hao Q, Karjalainen T, van den Bekerom M, Noorduyn J, Lytvyn L, Siemieniuk RAC, Albin A, Shunjie SC, Fisch F, Proulx L, Guyatt G, Agoritsas T, Poolman RW (2019)
Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline
BMJ, 364, l294
DOI 10.1136/bmj.l294, PubMed 30728120

Vervoort T, Karos K, Johnson D, Sütterlin S, Van Ryckeghem D (2019)
Parental emotion and pain control behaviour when faced with child's pain: the emotion regulatory role of parental pain-related attention-set shifting and heart rate variability
Pain, 160 (2), 322-333
DOI 10.1097/j.pain.0000000000001402, PubMed 30247182

Vohra R, Dalgaard LM, Vibaek J, Langbøl MA, Bergersen LH, Olsen NV, Hassel B, Chaudhry FA, Kolko M (2019)
Potential metabolic markers in glaucoma and their regulation in response to hypoxia
Acta Ophthalmol (in press)
DOI 10.1111/aos.14021, PubMed 30690927

Watila MM, Xiao F, Keezer MR, Miserocchi A, Winkler AS, McEvoy AW, Sander JW (2019)
Epilepsy surgery in low- and middle-income countries: A scoping review
Epilepsy Behav, 92, 311-326 (in press)
DOI 10.1016/j.yebeh.2019.01.001, PubMed 30738248

Weisser KH, Diseth TH, Boye B, Faerden A, Ekeberg Ø (2019)
Examining the organization and quality of the psychiatric consultative service in Norway
Nord J Psychiatry, 73 (1), 9-15
DOI 10.1080/08039488.2018.1525426, PubMed 30661436

Zahl SM, Egge A, Helseth E, Wester K (2019)
Clinical, Radiological, and Demographic Details of Benign External Hydrocephalus: A Population-Based Study
Pediatr Neurol (in press)
DOI 10.1016/j.pediatrneurol.2019.01.015, PubMed 30808532

Zak N, Bøen E, Boye B, Andreassen OA, Doan NT, Malt UF, Westlye LT, Elvsåshagen T (2019)
Mood episodes are associated with increased cortical thinning: a longitudinal study of bipolar disorder type II
Bipolar Disord (in press)
DOI 10.1111/bdi.12771, PubMed 30864260

 
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