Publications

Publications published since 1987 from OUS - Metastasis - molecular studies and development of methods

240 publications found

Publications 2019

  1. Crosbie EJ, Ryan NAJ, Arends MJ, Bosse T, Burn J, Cornes JM, Crawford R, Eccles D, Frayling IM, Ghaem-Maghami S, Hampel H, Kauff ND, Kitchener HC, Kitson SJ, Manchanda R, McMahon RFT, Monahan KJ, Menon U, Møller P, Möslein G, Rosenthal A, Sasieni P, Seif MW, Singh N, Skarrott P et al. (2019)
    The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome
    Genet Med, 21 (10), 2390-2400
    DOI 10.1038/s41436-019-0489-y, PubMed 30918358
  2. Della Valle A, Rossi BM, Palmero EI, Antelo M, Vaccaro CA, López-Kostner F, Alvarez K, Cruz-Correa M, Bruno LI, Forones NM, Mindiola JAR, Buleje J, Spirandelli F, Bohorquez M, Cock-Rada AM, Sullcahuaman Y, Nascimento I, Abe-Sandes K, Lino-Silva LS, Petracchi F, Mampel A, Rodriguez Y, Rossi NT, Yañez CB, Rubio C et al. (2019)
    A snapshot of current genetic testing practice in Lynch syndrome: The results of a representative survey of 33 Latin American existing centres/registries
    Eur J Cancer, 119, 112-121
    DOI 10.1016/j.ejca.2019.07.017, PubMed 31442815
  3. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2019)
    Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med (in press)
    DOI 10.1038/s41436-019-0596-9, PubMed 31337882
  4. Flørenes VA, Flem-Karlsen K, McFadden E, Bergheim IR, Nygaard V, Nygård V, Farstad IN, Øy GF, Emilsen E, Giller-Fleten K, Ree AH, Flatmark K, Gullestad HP, Hermann R, Ryder T, Wernhoff P, Mælandsmo GM (2019)
    A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases
    Transl Oncol, 12 (7), 951-958
    DOI 10.1016/j.tranon.2019.04.001, PubMed 31096111
  5. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2019)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res (in press)
    DOI 10.1093/nar/gkz885, PubMed 31598695
  6. Kanduri C, Bock C, Gundersen S, Hovig E, Sandve GK (2019)
    Colocalization analyses of genomic elements: approaches, recommendations and challenges
    Bioinformatics, 35 (9), 1615-1624
    DOI 10.1093/bioinformatics/bty835, PubMed 30307532
  7. Kotsopoulos J, Lubinski J, Lynch HT, Tung N, Armel S, Senter L, Singer CF, Fruscio R, Couch F, Weitzel JN, Karlan B, Foulkes WD, Moller P, Eisen A, Ainsworth P, Neuhausen SL, Olopade O, Sun P, Gronwald J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2019)
    Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 175 (2), 443-449
    DOI 10.1007/s10549-019-05162-7, PubMed 30756284
  8. Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
    Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
    Cold Spring Harb Mol Case Stud, 5 (2)
    DOI 10.1101/mcs.a003566, PubMed 30862609
  9. Metcalfe K, Eisen A, Senter L, Armel S, Bordeleau L, Meschino WS, Pal T, Lynch HT, Tung NM, Kwong A, Ainsworth P, Karlan B, Moller P, Eng C, Weitzel JN, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2019)
    International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation
    Br J Cancer, 121 (1), 15-21
    DOI 10.1038/s41416-019-0446-1, PubMed 30971774
  10. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2019)
    Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift
    Cancers (Basel), 11 (2)
    DOI 10.3390/cancers11020132, PubMed 30678073
  11. Njølstad PR, Andreassen OA, Brunak S, Børglum AD, Dillner J, Esko T, Franks PW, Freimer N, Groop L, Heimer H, Hougaard DM, Hovig E, Hveem K, Jalanko A, Kaprio J, Knudsen GP, Melbye M, Metspalu A, Mortensen PB, Palmgren J, Palotie A, Reed W, Stefánsson H, Stitziel NO, Sullivan PF et al. (2019)
    Roadmap for a precision-medicine initiative in the Nordic region
    Nat Genet, 51 (6), 924-930
    DOI 10.1038/s41588-019-0391-1, PubMed 30988515
  12. Ree AH, Nygaard V, Russnes HG, Heinrich D, Nygaard V, Johansen C, Bergheim IR, Hovig E, Beiske K, Negård A, Børresen-Dale AL, Flatmark K, Mælandsmo GM (2019)
    Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
    Cancer Immunol Res, 7 (5), 701-706
    DOI 10.1158/2326-6066.CIR-18-0777, PubMed 30804006
  13. Seppälä TT, Ahadova A, Dominguez-Valentin M, Macrae F, Evans DG, Therkildsen C, Sampson J, Scott R, Burn J, Möslein G, Bernstein I, Holinski-Feder E, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lautrup CK, Lindblom A, Plazzer JP, Winship I, Tjandra D, Katz LH, Aretz S, Hüneburg R, Holzapfel S, Heinimann K et al. (2019)
    Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report
    Hered Cancer Clin Pract, 17, 8
    DOI 10.1186/s13053-019-0106-8, PubMed 30858900
  14. Ten Broeke SW, Rodríguez-Girondo M, Suerink M, Aretz S, Bernstein I, Capellá G, Engel C, Gomez-Garcia EB, van Hest LP, von Knebel Doeberitz M, Lagerstedt-Robinson K, Letteboer TGW, Moller P, van Os TA, Pineda M, Rahner N, Olderode-Berends MJW, von Salomé J, Schackert HK, Spruijt L, Steinke-Lange V, Wagner A, Tops CMJ, Nielsen M (2019)
    The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect
    Cancer Epidemiol Biomarkers Prev, 28 (6), 1010-1014
    DOI 10.1158/1055-9965.EPI-18-0576, PubMed 30824524

Publications 2018

  1. Birkeland E, Zhang S, Poduval D, Geisler J, Nakken S, Vodak D, Meza-Zepeda LA, Hovig E, Myklebost O, Knappskog S, Lønning PE (2018)
    Patterns of genomic evolution in advanced melanoma
    Nat Commun, 9 (1), 2665
    DOI 10.1038/s41467-018-05063-1, PubMed 29991680
  2. Björklund AT, Carlsten M, Sohlberg E, Liu LL, Clancy T, Karimi M, Cooley S, Miller JS, Klimkowska M, Schaffer M, Watz E, Wikström K, Blomberg P, Wahlin BE, Palma M, Hansson L, Ljungman P, Hellström-Lindberg E, Ljunggren HG, Malmberg KJ (2018)
    Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
    Clin Cancer Res, 24 (8), 1834-1844
    DOI 10.1158/1078-0432.CCR-17-3196, PubMed 29444931
  3. Dominguez-Valentin M, Evans DGR, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds
    Hered Cancer Clin Pract, 16, 4
    DOI 10.1186/s13053-018-0086-0, PubMed 29371908
  4. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families
    Fam Cancer, 17 (1), 141-153
    DOI 10.1007/s10689-017-0011-0, PubMed 28608266
  5. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Identification of genetic variants for clinical management of familial colorectal tumors
    BMC Med Genet, 19 (1), 26
    DOI 10.1186/s12881-018-0533-9, PubMed 29458332
  6. Ebenesersdóttir SS, Sandoval-Velasco M, Gunnarsdóttir ED, Jagadeesan A, Guðmundsdóttir VB, Thordardóttir EL, Einarsdóttir MS, Moore KHS, Sigurðsson Á, Magnúsdóttir DN, Jónsson H, Snorradóttir S, Hovig E, Møller P, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Cavalleri GL, Gilbert E, Lalueza-Fox C, Walser JW, Kristjánsdóttir S, Gopalakrishnan S et al. (2018)
    Ancient genomes from Iceland reveal the making of a human population
    Science, 360 (6392), 1028-1032
    DOI 10.1126/science.aar2625, PubMed 29853688
  7. Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, Olopade O, Zakalik D, Lubinski J, Narod SA, Kotsopoulos J, Hereditary Breast Cancer Clinical Study Group (2018)
    Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers
    Int J Epidemiol, 47 (3), 987-997
    DOI 10.1093/ije/dyy039, PubMed 29547931
  8. Kotsopoulos J, Gronwald J, Karlan B, Rosen B, Huzarski T, Moller P, Lynch HT, Singer CF, Senter L, Neuhausen SL, Tung N, Eisen A, Foulkes WD, Ainsworth P, Sun P, Lubinski J, Narod SA, Hereditary Ovarian Cancer Clinical Study Group (2018)
    Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 150 (1), 85-91
    DOI 10.1016/j.ygyno.2018.05.011, PubMed 29793803
  9. Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2018)
    Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers
    JAMA Oncol, 4 (8), 1059-1065
    DOI 10.1001/jamaoncol.2018.0211, PubMed 29710224
  10. Møller P, Hovig E (2018)
    Retraction Note to: The BRCA2 variant c.68-7 T > A is associated with breast cancer
    Hered Cancer Clin Pract, 16, 10
    DOI 10.1186/s13053-018-0093-1, PubMed 29745381
  11. Vaccaro CA, López-Kostner F, Adriana DV, Palmero EI, Rossi BM, Antelo M, Solano A, Carraro DM, Forones NM, Bohorquez M, Lino-Silva LS, Buleje J, Spirandelli F, Abe-Sandes K, Nascimento I, Sullcahuaman Y, Sarroca C, Gonzalez ML, Herrando AI, Alvarez K, Neffa F, Galvão HC, Esperon P, Golubicki M, Cisterna D et al. (2018)
    From colorectal cancer pattern to the characterization of individuals at risk: Picture for genetic research in Latin America
    Int J Cancer, 145 (2), 318-326
    DOI 10.1002/ijc.31920, PubMed 30303536
  12. Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
    Sample-Index Misassignment Impacts Tumour Exome Sequencing
    Sci Rep, 8 (1), 5307
    DOI 10.1038/s41598-018-23563-4, PubMed 29593270

Publications 2017

  1. Arstad C, Refinetti P, Kristensen AT, Giercksky KE, Ekstrøm PO (2017)
    Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?
    BMC Cancer, 17 (1), 406
    DOI 10.1186/s12885-017-3365-7, PubMed 28592327
  2. Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
    Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
    Curr Pharm Des, 23 (32), 4716-4725
    DOI 10.2174/1381612823666170710154936, PubMed 28699527
  3. Domanska D, Vodák D, Lund-Andersen C, Salvatore S, Hovig E, Sandve GK (2017)
    The rainfall plot: its motivation, characteristics and pitfalls
    BMC Bioinformatics, 18 (1), 264
    DOI 10.1186/s12859-017-1679-8, PubMed 28521741
  4. Helland Å, Brustugun OT, Nakken S, Halvorsen AR, Dønnem T, Bremnes R, Busund LT, Sun J, Lorenz S, Solberg SK, Jørgensen LH, Vodak D, Myklebost O, Hovig E, Meza-Zepeda LA (2017)
    High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival
    Int J Cancer, 141 (1), 184-190
    DOI 10.1002/ijc.30726, PubMed 28387924
  5. Kanduri C, Domanska D, Hovig E, Sandve GK (2017)
    Genome build information is an essential part of genomic track files
    Genome Biol, 18 (1), 175
    DOI 10.1186/s13059-017-1312-1, PubMed 28911336
  6. Meisal R, Rounge TB, Christiansen IK, Eieland AK, Worren MM, Molden TF, Kommedal Ø, Hovig E, Leegaard TM, Ambur OH (2017)
    HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
    PLoS One, 12 (1), e0169074
    DOI 10.1371/journal.pone.0169074, PubMed 28045981
  7. Møller P, Hovig E (2017)
    The BRCA2 variant c.68-7 T>A is associated with breast cancer
    Hered Cancer Clin Pract, 15, 20 (Retracted)
    DOI 10.1186/s13053-017-0080-y, PubMed 29158857
  8. Møller P, Seppälä TT, Bernstein I, Holinski-Feder E, Sala P, Gareth Evans D, Lindblom A, Macrae F, Blanco I, Sijmons RH, Jeffries J, Vasen HFA, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen JT, Jenkins MA, Green K, Lalloo F, Sunde L, Mints M et al. (2017)
    Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
    Gut, 67 (7), 1306-1316
    DOI 10.1136/gutjnl-2017-314057, PubMed 28754778
  9. Namløs HM, Zaikova O, Bjerkehagen B, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2017)
    Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report
    BMC Cancer, 17 (1), 29
    DOI 10.1186/s12885-016-2992-8, PubMed 28061772
  10. Nygaard V, Rødland EA, Hovig E (2017)
    Reply to Towfic and others' letter to the editor
    Biostatistics, 18 (3), 586-587
    DOI 10.1093/biostatistics/kxx001, PubMed 28334081
  11. Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
    Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
    ESMO Open, 2 (2), e000158
    DOI 10.1136/esmoopen-2017-000158, PubMed 28761742
  12. Refinetti P, Arstad C, Thilly WG, Morgenthaler S, Ekstrøm PO (2017)
    Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis
    BMC Clin Pathol, 17, 6
    DOI 10.1186/s12907-017-0042-3, PubMed 28405177
  13. Rossi BM, Palmero EI, López-Kostner F, Sarroca C, Vaccaro CA, Spirandelli F, Ashton-Prolla P, Rodriguez Y, de Campos Reis Galvão H, Reis RM, Escremim de Paula A, Capochin Romagnolo LG, Alvarez K, Della Valle A, Neffa F, Kalfayan PG, Spirandelli E, Chialina S, Gutiérrez Angulo M, Castro-Mujica MDC, Sanchez de Monte J, Quispe R, da Silva SD, Rossi NT, Barletta-Carrillo C et al. (2017)
    A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
    BMC Cancer, 17 (1), 623
    DOI 10.1186/s12885-017-3599-4, PubMed 28874130
  14. Seppälä T, Pylvänäinen K, Evans DG, Järvinen H, Renkonen-Sinisalo L, Bernstein I, Holinski-Feder E, Sala P, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Genuardi M, Green K et al. (2017)
    Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report
    Hered Cancer Clin Pract, 15, 18
    DOI 10.1186/s13053-017-0078-5, PubMed 29046738
  15. Simovski B, Vodák D, Gundersen S, Domanska D, Azab A, Holden L, Holden M, Grytten I, Rand K, Drabløs F, Johansen M, Mora A, Lund-Andersen C, Fromm B, Eskeland R, Gabrielsen OS, Ferkingstad E, Nakken S, Bengtsen M, Nederbragt AJ, Thorarensen HS, Akse JA, Glad I, Hovig E, Sandve GK (2017)
    GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
    Gigascience, 6 (7), 1-12
    DOI 10.1093/gigascience/gix032, PubMed 28459977
  16. Østrup O, Dagenborg VJ, Rødland EA, Skarpeteig V, Silwal-Pandit L, Grzyb K, Berstad AE, Fretland ÅA, Mælandsmo GM, Børresen-Dale AL, Ree AH, Edwin B, Nygaard V, Flatmark K (2017)
    Molecular signatures reflecting microenvironmental metabolism and chemotherapy-induced immunogenic cell death in colorectal liver metastases
    Oncotarget, 8 (44), 76290-76304
    DOI 10.18632/oncotarget.19350, PubMed 29100312

Publications 2016

  1. Alver TN, Lavelle TJ, Longva AS, Øy GF, Hovig E, Bøe SL (2016)
    MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma
    Oncotarget, 7 (34), 55128-55140
    DOI 10.18632/oncotarget.10422, PubMed 27391157
  2. Arstad C, Refinetti P, Warren D, Giercksky KE, Ekstrøm PO (2016)
    Scanning the mitochondrial genome for mutations by cycling temperature capillary electrophoresis
    Mitochondrial DNA A DNA Mapp Seq Anal, 29 (1), 19-30
    DOI 10.1080/24701394.2016.1233532, PubMed 27728990
  3. Björklund AT, Clancy T, Goodridge JP, Béziat V, Schaffer M, Hovig E, Ljunggren HG, Ljungman PT, Malmberg KJ (2016)
    Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
    J Immunol, 196 (3), 1400-11
    DOI 10.4049/jimmunol.1501434, PubMed 26746188
  4. Børnich C, Grytten I, Hovig E, Paulsen J, Čech M, Sandve GK (2016)
    Galaxy Portal: interacting with the galaxy platform through mobile devices
    Bioinformatics, 32 (11), 1743-5
    DOI 10.1093/bioinformatics/btw042, PubMed 26819474
  5. Clancy T, Hovig E (2016)
    Profiling networks of distinct immune-cells in tumors
    BMC Bioinformatics, 17 (1), 263
    DOI 10.1186/s12859-016-1141-3, PubMed 27377892
  6. Di Stefano M, Paulsen J, Lien TG, Hovig E, Micheletti C (2016)
    Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization
    Sci Rep, 6, 35985
    DOI 10.1038/srep35985, PubMed 27786255
  7. Halvorsen AR, Silwal-Pandit L, Meza-Zepeda LA, Vodak D, Vu P, Sagerup C, Hovig E, Myklebost O, Børresen-Dale AL, Brustugun OT, Helland Å (2016)
    TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
    Front Genet, 7, 85
    DOI 10.3389/fgene.2016.00085, PubMed 27242894
  8. Haugvik SP, Vodák D, Haugom L, Hovig E, Gladhaug IP, Heim S, Micci F (2016)
    Transcriptomic Profiling of Tumor Aggressiveness in Sporadic Nonfunctioning Pancreatic Neuroendocrine Neoplasms
    Pancreas, 45 (8), 1196-203
    DOI 10.1097/MPA.0000000000000610, PubMed 26918873
  9. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    DOI 10.1002/ijc.30142, PubMed 27082076
  10. Jonsson M, Ragnum HB, Julin CH, Yeramian A, Clancy T, Frikstad KM, Seierstad T, Stokke T, Matias-Guiu X, Ree AH, Flatmark K, Lyng H (2016)
    Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
    Br J Cancer, 115 (8), 929-939
    DOI 10.1038/bjc.2016.278, PubMed 27599042
  11. Joshi S, Schjølberg AR, Ekstrøm PO, De Angelis PM, Zucknick M, Andersen SN, Clausen OP (2016)
    Tp53/p53 status in keratoacanthomas
    J Cutan Pathol, 43 (7), 571-8
    DOI 10.1111/cup.12713, PubMed 27020606
  12. Kotsopoulos J, Huzarski T, Gronwald J, Moller P, Lynch HT, Neuhausen SL, Senter L, Demsky R, Foulkes WD, Eng C, Karlan B, Tung N, Singer CF, Sun P, Lubinski J, Narod SA (2016)
    Hormone replacement therapy after menopause and risk of breast cancer in BRCA1 mutation carriers: a case-control study
    Breast Cancer Res Treat, 155 (2), 365-73
    DOI 10.1007/s10549-016-3685-3, PubMed 26780555
  13. Kotsopoulos J, Huzarski T, Gronwald J, Singer CF, Moller P, Lynch HT, Armel S, Karlan B, Foulkes WD, Neuhausen SL, Senter L, Tung N, Weitzel JN, Eisen A, Metcalfe K, Eng C, Pal T, Evans G, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2016)
    Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
    J Natl Cancer Inst, 109 (1)
    DOI 10.1093/jnci/djw177, PubMed 27601060
  14. Landfors M, Nakken S, Fusser M, Dahl JA, Klungland A, Fedorcsak P (2016)
    Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations
    Fertil Steril, 105 (5), 1170-1179.e5
    DOI 10.1016/j.fertnstert.2016.01.002, PubMed 26820768
  15. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Green K, Lalloo F, Sunde L, Mints M et al. (2016)
    Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
    Gut, 66 (9), 1657-1664
    DOI 10.1136/gutjnl-2016-311403, PubMed 27261338
  16. Seip K, Fleten KG, Barkovskaya A, Nygaard V, Haugen MH, Engesæter BØ, Mælandsmo GM, Prasmickaite L (2016)
    Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors
    Oncotarget, 7 (15), 19997-20015
    DOI 10.18632/oncotarget.7671, PubMed 26918352
  17. Späth F, Andersson U, Dahlin AM, Langseth H, Hovig E, Johannesen TB, Grankvist K, Björkblom B, Wibom C, Melin B (2016)
    Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study
    Tumour Biol, 37 (8), 11065-72
    DOI 10.1007/s13277-015-4742-y, PubMed 26906551

Publications 2015

  1. Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S et al. (2015)
    A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
    Nat Commun, 6, 10001
    DOI 10.1038/ncomms10001, PubMed 26647970
  2. Bengtsen M, Klepper K, Gundersen S, Cuervo I, Drabløs F, Hovig E, Sandve GK, Gabrielsen OS, Eskeland R (2015)
    c-Myb Binding Sites in Haematopoietic Chromatin Landscapes
    PLoS One, 10 (7), e0133280
    DOI 10.1371/journal.pone.0133280, PubMed 26208222
  3. Bettum IJ, Gorad SS, Barkovskaya A, Pettersen S, Moestue SA, Vasiliauskaite K, Tenstad E, Øyjord T, Risa Ø, Nygaard V, Mælandsmo GM, Prasmickaite L (2015)
    Metabolic reprogramming supports the invasive phenotype in malignant melanoma
    Cancer Lett, 366 (1), 71-83
    DOI 10.1016/j.canlet.2015.06.006, PubMed 26095603
  4. Christiansen IK, Sandve GK, Schmitz M, Dürst M, Hovig E (2015)
    Transcriptionally active regions are the preferred targets for chromosomal HPV integration in cervical carcinogenesis
    PLoS One, 10 (3), e0119566
    DOI 10.1371/journal.pone.0119566, PubMed 25793388
  5. Ekstrøm PO, Nakken S, Johansen M, Hovig E (2015)
    Automated amplicon design suitable for analysis of DNA variants by melting techniques
    BMC Res Notes, 8, 667
    DOI 10.1186/s13104-015-1624-8, PubMed 26559640
  6. Heramb C, Ekstrøm PO, Tharmaratnam K, Hovig E, Møller P, Mæhle L (2015)
    Ten modifiers of BRCA1 penetrance validated in a Norwegian series
    Hered Cancer Clin Pract, 13 (1), 14
    DOI 10.1186/s13053-015-0035-0, PubMed 26052370
  7. Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
    PLoS One, 10 (2), e0117261
    DOI 10.1371/journal.pone.0117261, PubMed 25706641
  8. Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
    Genom Data, 5, 176-83
    DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252
  9. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Green K, Lalloo F, Sunde L, Mints M, Bertario L et al. (2015)
    Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
    Gut, 66 (3), 464-472
    DOI 10.1136/gutjnl-2015-309675, PubMed 26657901
  10. Nygaard V, Rødland EA, Hovig E (2015)
    Methods that remove batch effects while retaining group differences may lead to exaggerated confidence in downstream analyses
    Biostatistics, 17 (1), 29-39
    DOI 10.1093/biostatistics/kxv027, PubMed 26272994
  11. Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A (2015)
    BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
    Blood Cancer J, 5, e299
    DOI 10.1038/bcj.2015.24, PubMed 25794135
  12. Rydbeck H, Sandve GK, Ferkingstad E, Simovski B, Rye M, Hovig E (2015)
    ClusTrack: feature extraction and similarity measures for clustering of genome-wide data sets
    PLoS One, 10 (4), e0123261
    DOI 10.1371/journal.pone.0123261, PubMed 25879845
  13. Wibom C, Späth F, Dahlin AM, Langseth H, Hovig E, Rajaraman P, Johannesen TB, Andersson U, Melin B (2015)
    Investigation of established genetic risk variants for glioma in prediagnostic samples from a population-based nested case-control study
    Cancer Epidemiol Biomarkers Prev, 24 (5), 810-6
    DOI 10.1158/1055-9965.EPI-14-1106, PubMed 25713050

Publications 2014

  1. Chilamakuri CS, Lorenz S, Madoui MA, Vodák D, Sun J, Hovig E, Myklebost O, Meza-Zepeda LA (2014)
    Performance comparison of four exome capture systems for deep sequencing
    BMC Genomics, 15, 449
    DOI 10.1186/1471-2164-15-449, PubMed 24912484
  2. Clancy T, Hovig E (2014)
    From proteomes to complexomes in the era of systems biology
    Proteomics, 14 (1), 24-41
    DOI 10.1002/pmic.201300230, PubMed 24243660
  3. Clancy T, Hovig E (2014)
    Differential protein network analysis of the immune cell lineage
    Biomed Res Int, 2014, 363408
    DOI 10.1155/2014/363408, PubMed 25309909
  4. Friis-Ottessen M, Burum-Auensen E, Schjølberg AR, Ekstrøm PO, Andersen SN, Clausen OP, De Angelis PM (2014)
    TP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitis
    Int J Mol Med, 35 (1), 24-30
    DOI 10.3892/ijmm.2014.1974, PubMed 25333414
  5. Nygård S, Reitan T, Clancy T, Nygaard V, Bjørnstad J, Skrbic B, Tønnessen T, Christensen G, Hovig E (2014)
    Identifying pathogenic processes by integrating microarray data with prior knowledge
    BMC Bioinformatics, 15, 115
    DOI 10.1186/1471-2105-15-115, PubMed 24758699
  6. Nygaard V, Prasmickaite L, Vasiliauskaite K, Clancy T, Hovig E (2014)
    Melanoma brain colonization involves the emergence of a brain-adaptive phenotype
    Oncoscience, 1 (1), 82-94
    DOI 10.18632/oncoscience.11, PubMed 25593989
  7. Paulsen J, Rødland EA, Holden L, Holden M, Hovig E (2014)
    A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions
    Nucleic Acids Res, 42 (18), e143
    DOI 10.1093/nar/gku738, PubMed 25114054

Publications 2013

  1. Bettum IJ, Vasiliauskaite K, Nygaard V, Clancy T, Pettersen SJ, Tenstad E, Mælandsmo GM, Prasmickaite L (2013)
    Metastasis-associated protein S100A4 induces a network of inflammatory cytokines that activate stromal cells to acquire pro-tumorigenic properties
    Cancer Lett, 344 (1), 28-39
    DOI 10.1016/j.canlet.2013.10.036, PubMed 24215866
  2. Bøe SL, Hovig E (2013)
    Light-induced mRNA transfection
    Methods Mol Biol, 969, 89-100
    DOI 10.1007/978-1-62703-260-5_6, PubMed 23296929
  3. Bøe SL, Jørgensen JA, Longva AS, Lavelle T, Sæbøe-Larssen S, Hovig E (2013)
    Light-controlled modulation of gene expression using polyamidoamine formulations
    Nucleic Acid Ther, 23 (2), 160-5
    DOI 10.1089/nat.2012.0413, PubMed 23530684
  4. Clancy T, Rødland EA, Nygard S, Hovig E (2013)
    Predicting physical interactions between protein complexes
    Mol Cell Proteomics, 12 (6), 1723-34
    DOI 10.1074/mcp.O112.019828, PubMed 23438732
  5. Fromm B, Worren MM, Hahn C, Hovig E, Bachmann L (2013)
    Substantial loss of conserved and gain of novel MicroRNA families in flatworms
    Mol Biol Evol, 30 (12), 2619-28
    DOI 10.1093/molbev/mst155, PubMed 24025793
  6. Jørgensen JA, Longva AS, Hovig E, Bøe SL (2013)
    Evaluation of biodegradable peptide carriers for light-directed targeting
    Nucleic Acid Ther, 23 (2), 131-9
    DOI 10.1089/nat.2012.0403, PubMed 23405950
  7. Lando M, Wilting SM, Snipstad K, Clancy T, Bierkens M, Aarnes EK, Holden M, Stokke T, Sundfør K, Holm R, Kristensen GB, Steenbergen RD, Lyng H (2013)
    Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling
    J Pathol, 230 (1), 59-69
    DOI 10.1002/path.4168, PubMed 23335387
  8. Lorvik KB, Haabeth OA, Clancy T, Bogen B, Corthay A (2013)
    Molecular profiling of tumor-specific TH1 cells activated in vivo
    Oncoimmunology, 2 (5), e24383
    DOI 10.4161/onci.24383, PubMed 23762808
  9. Paulsen J, Lien TG, Sandve GK, Holden L, Borgan O, Glad IK, Hovig E (2013)
    Handling realistic assumptions in hypothesis testing of 3D co-localization of genomic elements
    Nucleic Acids Res, 41 (10), 5164-74
    DOI 10.1093/nar/gkt227, PubMed 23571755
  10. Sandve GK, Gundersen S, Johansen M, Glad IK, Gunathasan K, Holden L, Holden M, Liestøl K, Nygård S, Nygaard V, Paulsen J, Rydbeck H, Trengereid K, Clancy T, Drabløs F, Ferkingstad E, Kalas M, Lien T, Rye MB, Frigessi A, Hovig E (2013)
    The Genomic HyperBrowser: an analysis web server for genome-scale data
    Nucleic Acids Res, 41 (Web Server issue), W133-41
    DOI 10.1093/nar/gkt342, PubMed 23632163
  11. Sandve GK, Nekrutenko A, Taylor J, Hovig E (2013)
    Ten simple rules for reproducible computational research
    PLoS Comput Biol, 9 (10), e1003285
    DOI 10.1371/journal.pcbi.1003285, PubMed 24204232
  12. Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K (2013)
    Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
    PLoS One, 8 (6), e66165
    DOI 10.1371/journal.pone.0066165, PubMed 23824282
  13. Yri OE, Ekstrøm PO, Hilden V, Gaudernack G, Liestøl K, Smeland EB, Holte H (2013)
    Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab
    Leuk Lymphoma, 54 (10), 2205-14
    DOI 10.3109/10428194.2013.774392, PubMed 23391141

Publications 2012

  1. Ekstrøm PO, Warren DJ, Thilly WG (2012)
    Separation principles of cycling temperature capillary electrophoresis
    Electrophoresis, 33 (7), 1162-8
    DOI 10.1002/elps.201100550, PubMed 22539319
  2. Jørgensen JA, Hovig E, Bøe SL (2012)
    Potent gene silencing in vitro at physiological pH using chitosan polymers
    Nucleic Acid Ther, 22 (2), 96-102
    DOI 10.1089/nat.2011.0335, PubMed 22480314
  3. Kresse SH, Rydbeck H, Skårn M, Namløs HM, Barragan-Polania AH, Cleton-Jansen AM, Serra M, Liestøl K, Hogendoorn PC, Hovig E, Myklebost O, Meza-Zepeda LA (2012)
    Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma
    PLoS One, 7 (11), e48262
    DOI 10.1371/journal.pone.0048262, PubMed 23144859
  4. Liu F, Kuo WP, Jenssen TK, Hovig E (2012)
    Performance comparison of multiple microarray platforms for gene expression profiling
    Methods Mol Biol, 802, 141-55
    DOI 10.1007/978-1-61779-400-1_10, PubMed 22130879
  5. Mattingsdal M, Brown AA, Djurovic S, Sønderby IE, Server A, Melle I, Agartz I, Hovig E, Jensen J, Andreassen OA (2012)
    Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
    Neuroimage, 70, 143-9
    DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185
  6. Nakken S, Johansen M, Fillebeen J, Berge OP, Kirkerød H, Jenssen TK, Hovig E (2012)
    CellLineMiner: a knowledge portal for human cell lines
    Bioinformation, 8 (22), 1119-22
    DOI 10.6026/97320630081119, PubMed 23251048
  7. Thingnes J, Lavelle TJ, Gjuvsland AB, Omholt SW, Hovig E (2012)
    Towards a quantitative understanding of the MITF-PIAS3-STAT3 connection
    BMC Syst Biol, 6, 11
    DOI 10.1186/1752-0509-6-11, PubMed 22316093
  8. Thingnes J, Lavelle TJ, Hovig E, Omholt SW (2012)
    Understanding the melanocyte distribution in human epidermis: an agent-based computational model approach
    PLoS One, 7 (7), e40377
    DOI 10.1371/journal.pone.0040377, PubMed 22792296
  9. Trachtenberg AJ, Robert JH, Abdalla AE, Fraser A, He SY, Lacy JN, Rivas-Morello C, Truong A, Hardiman G, Ohno-Machado L, Liu F, Hovig E, Kuo WP (2012)
    A primer on the current state of microarray technologies
    Methods Mol Biol, 802, 3-17
    DOI 10.1007/978-1-61779-400-1_1, PubMed 22130870
  10. Yri OE, Ekstrøm PO, Hilden V, Gaudernack G, Liestøl K, Smeland EB, Holte H (2012)
    Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma
    Leuk Lymphoma, 53 (10), 1934-44
    DOI 10.3109/10428194.2012.682307, PubMed 22475179

Publications 2011

  1. Bruhn S, Barrenäs F, Mobini R, Andersson BA, Chavali S, Egan BS, Hovig E, Sandve GK, Langston MA, Rogers G, Wang H, Benson M (2011)
    Increased expression of IRF4 and ETS1 in CD4+ cells from patients with intermittent allergic rhinitis
    Allergy, 67 (1), 33-40
    DOI 10.1111/j.1398-9995.2011.02707.x, PubMed 21919915
  2. Bøe S, Prasmickaite L, Engesæter B, Hovig E (2011)
    Light-directed delivery of nucleic acids
    Methods Mol Biol, 764, 107-21
    DOI 10.1007/978-1-61779-188-8_7, PubMed 21748636
  3. Bøe SL, Longva AS, Hovig E (2011)
    A novel photosensitizer for light-controlled gene silencing
    Nucleic Acid Ther, 21 (5), 359-67
    DOI 10.1089/nat.2011.0309, PubMed 22004417
  4. Clancy T, Pedicini M, Castiglione F, Santoni D, Nygaard V, Lavelle TJ, Benson M, Hovig E (2011)
    Immunological network signatures of cancer progression and survival
    BMC Med Genomics, 4, 28
    DOI 10.1186/1755-8794-4-28, PubMed 21453479
  5. De Beule J, Hovig E, Benson M (2011)
    Introducing Dynamics into the Field of Biosemiotics A Formal Account with Examples from Language and Immunology
    Biosemiotics, 4 (1), 5-24
  6. Gundersen S, Kalaš M, Abul O, Frigessi A, Hovig E, Sandve GK (2011)
    Identifying elemental genomic track types and representing them uniformly
    BMC Bioinformatics, 12, 494
    DOI 10.1186/1471-2105-12-494, PubMed 22208806
  7. Halle C, Lando M, Svendsrud DH, Clancy T, Holden M, Sundfør K, Kristensen GB, Holm R, Lyng H (2011)
    Membranous expression of ectodomain isoforms of the epidermal growth factor receptor predicts outcome after chemoradiotherapy of lymph node-negative cervical cancer
    Clin Cancer Res, 17 (16), 5501-12
    DOI 10.1158/1078-0432.CCR-11-0297, PubMed 21737508
  8. Hjortland GO, Meza-Zepeda LA, Beiske K, Ree AH, Tveito S, Hoifodt H, Bohler PJ, Hole KH, Myklebost O, Fodstad O, Smeland S, Hovig E (2011)
    Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma
    BMC Cancer, 11, 455
    DOI 10.1186/1471-2407-11-455, PubMed 22014070
  9. Sandve GK, Gundersen S, Rydbeck H, Glad IK, Holden L, Holden M, Liestøl K, Clancy T, Drabløs F, Ferkingstad E, Johansen M, Nygaard V, Tøstesen E, Frigessi A, Hovig E (2011)
    The differential disease regulome
    BMC Genomics, 12, 353
    DOI 10.1186/1471-2164-12-353, PubMed 21736759
  10. Selmer KK, Gilfillan GD, Strømme P, Lyle R, Hughes T, Hjorthaug HS, Brandal K, Nakken S, Misceo D, Egeland T, Munthe LA, Braekken SK, Undlien DE (2011)
    A mild form of Mucopolysaccharidosis IIIB diagnosed with targeted next-generation sequencing of linked genomic regions
    Eur J Hum Genet, 20 (1), 58-63
    DOI 10.1038/ejhg.2011.126, PubMed 21712855
  11. Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
    CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
    Genes Immun, 12 (8), 653-62
    DOI 10.1038/gene.2011.43, PubMed 21716316

Publications 2010

  1. Beck H, Nähse V, Larsen MS, Groth P, Clancy T, Lees M, Jørgensen M, Helleday T, Syljuåsen RG, Sørensen CS (2010)
    Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
    J Cell Biol, 188 (5), 629-38
    DOI 10.1083/jcb.200905059, PubMed 20194642
  2. Bøe S, Saebøe-Larssen S, Hovig E (2010)
    Light-induced gene expression using messenger RNA molecules
    Oligonucleotides, 20 (1), 1-6
    DOI 10.1089/oli.2009.0209, PubMed 20038251
  3. Bøe SL, Longva AS, Hovig E (2010)
    Cyclodextrin-containing polymer delivery system for light-directed siRNA gene silencing
    Oligonucleotides, 20 (4), 175-82
    DOI 10.1089/oli.2010.0230, PubMed 20645877
  4. Cekaite L, Clancy T, Sioud M (2010)
    Increased miR-21 expression during human monocyte differentiation into DCs
    Front Biosci (Elite Ed), 2, 818-28
    PubMed 20515755
  5. Nakken S, Rødland EA, Hovig E (2010)
    Impact of DNA physical properties on local sequence bias of human mutation
    Hum Mutat, 31 (12), 1316-25
    DOI 10.1002/humu.21371, PubMed 20886615
  6. Pedicini M, Barrenäs F, Clancy T, Castiglione F, Hovig E, Kanduri K, Santoni D, Benson M (2010)
    Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation
    PLoS Comput Biol, 6 (12), e1001032
    DOI 10.1371/journal.pcbi.1001032, PubMed 21187905
  7. Sandve GK, Gundersen S, Rydbeck H, Glad IK, Holden L, Holden M, Liestøl K, Clancy T, Ferkingstad E, Johansen M, Nygaard V, Tøstesen E, Frigessi A, Hovig E (2010)
    The Genomic HyperBrowser: inferential genomics at the sequence level
    Genome Biol, 11 (12), R121
    DOI 10.1186/gb-2010-11-12-r121, PubMed 21182759
  8. Sioud M, Cekaite L (2010)
    Profiling of miRNA expression and prediction of target genes
    Methods Mol Biol, 629, 257-71
    DOI 10.1007/978-1-60761-657-3_16, PubMed 20387154

Publications 2009

  1. Cekaite L, Hovig E, Sioud M (2009)
    Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
    Methods Mol Biol, 524, 273-85
    DOI 10.1007/978-1-59745-450-6_20, PubMed 19377952
  2. Lehne G, Grasmo-Wendler UH, Berner JM, Meza-Zepeda LA, Adamsen BL, Flack A, Reiner A, Clausen OP, Hovig E, Myklebost O (2009)
    Upregulation of stem cell genes in multidrug resistant K562 leukemia cells
    Leuk Res, 33 (10), 1379-85
    DOI 10.1016/j.leukres.2009.03.028, PubMed 19394083
  3. Nakken S, Rognes T, Hovig E (2009)
    The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts
    Nucleic Acids Res, 37 (17), 5749-56
    DOI 10.1093/nar/gkp590, PubMed 19617376
  4. Nakken S, Rødland EA, Rognes T, Hovig E (2009)
    Large-scale inference of the point mutational spectrum in human segmental duplications
    BMC Genomics, 10, 43
    DOI 10.1186/1471-2164-10-43, PubMed 19161616
  5. Nygaard V, Hovig E (2009)
    Methods for quantitation of gene expression
    Front Biosci (Landmark Ed), 14, 552-69
    DOI 10.2741/3262, PubMed 19273085
  6. Thingnes J, Oyehaug L, Hovig E, Omholt SW (2009)
    The mathematics of tanning
    BMC Syst Biol, 3, 60
    DOI 10.1186/1752-0509-3-60, PubMed 19505344

Publications 2008

  1. Boe S, Longva AS, Hovig E (2008)
    Evaluation of various polyethylenimine formulations for light-controlled gene silencing using small interfering RNA molecules
    Oligonucleotides, 18 (2), 123-32
    DOI 10.1089/oli.2008.0131, PubMed 18637730
  2. Boye K, Grotterød I, Aasheim HC, Hovig E, Maelandsmo GM (2008)
    Activation of NF-kappaB by extracellular S100A4: analysis of signal transduction mechanisms and identification of target genes
    Int J Cancer, 123 (6), 1301-10
    DOI 10.1002/ijc.23617, PubMed 18548584
  3. Kraus I, Driesch C, Vinokurova S, Hovig E, Schneider A, von Knebel Doeberitz M, Dürst M (2008)
    The majority of viral-cellular fusion transcripts in cervical carcinomas cotranscribe cellular sequences of known or predicted genes
    Cancer Res, 68 (7), 2514-22
    DOI 10.1158/0008-5472.CAN-07-2776, PubMed 18381461
  4. Lyng H, Lando M, Brøvig RS, Svendsrud DH, Johansen M, Galteland E, Brustugun OT, Meza-Zepeda LA, Myklebost O, Kristensen GB, Hovig E, Stokke T (2008)
    GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
    Genome Biol, 9 (5), R86
    DOI 10.1186/gb-2008-9-5-r86, PubMed 18500990
  5. Nygaard V, Hovig E (2008)
    Cell sampling and global nucleic acid amplification
    SEB Exp Biol Ser, 61, 17-36
    PubMed 18709735
  6. Nygaard V, Liu F, Holden M, Kuo WP, Trimarchi J, Ohno-Machado L, Cepko CL, Frigessi A, Glad IK, Wiel MA, Hovig E, Lyng H (2008)
    Validation of oligoarrays for quantitative exploration of the transcriptome
    BMC Genomics, 9, 258
    DOI 10.1186/1471-2164-9-258, PubMed 18513391
  7. Sioud M, Cekaite L (2008)
    Expression profiling of microRNAs in cancer cells: technical considerations
    Methods Mol Biol, 439, 179-90
    DOI 10.1007/978-1-59745-188-8_12, PubMed 18370103
  8. Tøstesen E (2008)
    A stitch in time: efficient computation of genomic DNA melting bubbles
    Algorithms Mol Biol, 3, 10
    DOI 10.1186/1748-7188-3-10, PubMed 18637171
  9. Tøstesen E, Sandve GK, Liu F, Hovig E (2008)
    Segmentation of DNA sequences into twostate regions and melting fork regions
    J Phys Condens Matter, 21 (3), 034109
    DOI 10.1088/0953-8984/21/3/034109, PubMed 21817254

Publications 2007

  1. Benson M, Steenhoff Hov DA, Clancy T, Hovig E, Rudemo M, Cardell LO (2007)
    Connectivity can be used to identify key genes in DNA microarray data: a study based on gene expression in nasal polyps before and after treatment with glucocorticoids
    Acta Otolaryngol, 127 (10), 1074-9
    DOI 10.1080/00016480701200277, PubMed 17851899
  2. Bøe S, Longva AS, Hovig E (2007)
    Photochemically induced gene silencing using small interfering RNA molecules in combination with lipid carriers
    Oligonucleotides, 17 (2), 166-73
    DOI 10.1089/oli.2007.0076, PubMed 17638521
  3. Cekaite L, Hovig E, Sioud M (2007)
    Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
    Methods Mol Biol, 360, 335-48
    DOI 10.1385/1-59745-165-7:335, PubMed 17172738
  4. Cekaite L, Peng Q, Reiner A, Shahzidi S, Tveito S, Furre IE, Hovig E (2007)
    Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
    BMC Genomics, 8, 273
    DOI 10.1186/1471-2164-8-273, PubMed 17692132
  5. Liu F, Jenssen TK, Trimarchi J, Punzo C, Cepko CL, Ohno-Machado L, Hovig E, Kuo WP (2007)
    Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates
    BMC Genomics, 8, 153
    DOI 10.1186/1471-2164-8-153, PubMed 17555589
  6. Liu F, Tøstesen E, Sundet JK, Jenssen TK, Bock C, Jerstad GI, Thilly WG, Hovig E (2007)
    The human genomic melting map
    PLoS Comput Biol, 3 (5), e93
    DOI 10.1371/journal.pcbi.0030093, PubMed 17511513
  7. Møller P, Hagen AI, Apold J, Maehle L, Clark N, Fiane B, Løvslett K, Hovig E, Vabø A (2007)
    Genetic epidemiology of BRCA mutations--family history detects less than 50% of the mutation carriers
    Eur J Cancer, 43 (11), 1713-7
    DOI 10.1016/j.ejca.2007.04.023, PubMed 17574839
  8. Sioud M, Furset G, Cekaite L (2007)
    Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
    Biochem Biophys Res Commun, 361 (1), 122-6
    DOI 10.1016/j.bbrc.2007.06.177, PubMed 17658482

Publications 2006

  1. Berner JM, Muller CR, Holden M, Wang J, Hovig E, Myklebost O (2006)
    Sampling effects on gene expression data from a human tumour xenograft
    Scand. J. Lab. Anim. Sci., 33 (1), 17-30
  2. Bøe S, Hovig E (2006)
    Photochemically induced gene silencing using PNA-peptide conjugates
    Oligonucleotides, 16 (2), 145-57
    DOI 10.1089/oli.2006.16.145, PubMed 16764538
  3. Cekaite L, Furset G, Hovig E, Sioud M (2006)
    Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
    J Mol Biol, 365 (1), 90-108
    DOI 10.1016/j.jmb.2006.09.034, PubMed 17054988
  4. Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF, Freeman MW, Seed B et al. (2006)
    A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies
    Nat Biotechnol, 24 (7), 832-40
    DOI 10.1038/nbt1217, PubMed 16823376
  5. Nygaard V, Hovig E (2006)
    Options available for profiling small samples: a review of sample amplification technology when combined with microarray profiling
    Nucleic Acids Res, 34 (3), 996-1014
    DOI 10.1093/nar/gkj499, PubMed 16473852
  6. Prasmickaite L, Cekaite L, Hellum M, Hovig E, Høgset A, Berg K (2006)
    Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
    FEBS Lett, 580 (24), 5739-46
    DOI 10.1016/j.febslet.2006.09.028, PubMed 17007842
  7. Stormorken A, Heintz KM, Andresen PA, Hovig E, Møller P (2006)
    MUTYH Mutations Do Not Cause HNPCC or Late Onset Familial Colorectal Cancer
    Hered Cancer Clin Pract, 4 (2), 90-3
    DOI 10.1186/1897-4287-4-2-90, PubMed 20223013

Publications 2005

  1. Gulliksen A, Solli LA, Drese KS, Sörensen O, Karlsen F, Rogne H, Hovig E, Sirevåg R (2005)
    Parallel nanoliter detection of cancer markers using polymer microchips
    Lab Chip, 5 (4), 416-20
    DOI 10.1039/b415525d, PubMed 15791339
  2. Jenssen TK, Hovig E (2005)
    Gene-expression profiling in breast cancer
    Lancet, 365 (9460), 634-5
    DOI 10.1016/S0140-6736(05)17959-8, PubMed 15721457
  3. Lyng H, Landsverk KS, Kristiansen E, DeAngelis PM, Ree AH, Myklebost O, Hovig E, Stokke T (2005)
    Response of malignant B lymphocytes to ionizing radiation: gene expression and genotype
    Int J Cancer, 115 (6), 935-42
    DOI 10.1002/ijc.20962, PubMed 15723354
  4. Nygaard V, Holden M, Løland A, Langaas M, Myklebost O, Hovig E (2005)
    Limitations of mRNA amplification from small-size cell samples
    BMC Genomics, 6, 147
    DOI 10.1186/1471-2164-6-147, PubMed 16253144
  5. Tøstesen E (2005)
    Partly melted DNA conformations obtained with a probability peak finding method
    Phys Rev E Stat Nonlin Soft Matter Phys, 71 (6 Pt 1), 061922
    DOI 10.1103/PhysRevE.71.061922, PubMed 16089780
  6. Tøstesen E, Jerstad GI, Hovig E (2005)
    Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles
    Nucleic Acids Res, 33 (Web Server issue), W573-6
    DOI 10.1093/nar/gki424, PubMed 15980539

Publications 2004

  1. Bjørge T, Lie AK, Hovig E, Gislefoss RE, Hansen S, Jellum E, Langseth H, Nustad K, Tropé CG, Dørum A (2004)
    BRCA1 mutations in ovarian cancer and borderline tumours in Norway: a nested case-control study
    Br J Cancer, 91 (10), 1829-34
    DOI 10.1038/sj.bjc.6602199, PubMed 15477862
  2. Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
    Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
    Proteomics, 4 (9), 2572-82
    DOI 10.1002/pmic.200300768, PubMed 15352232
  3. Cekaite L, Hovig E, Hauge HH (2004)
    Double-sided silicon strip detectors: new applications within genomics and proteomics
    Nucl. Instrum. Methods Phys. Res. Sect. A-Accel. Spectrom. Dect. Assoc. Equip., 527 (1-2), 68-72
  4. Cruciani V, Heintz KM, Husøy T, Hovig E, Warren DJ, Mikalsen SO (2004)
    The detection of hamster connexins: a comparison of expression profiles with wild-type mouse and the cancer-prone Min mouse
    Cell Commun Adhes, 11 (5-6), 155-71
    DOI 10.1080/15419060500242877, PubMed 16194882
  5. Ekstrøm PO, Bjørge T, Dørum A, Longva AS, Heintz KM, Warren DJ, Hansen S, Gislefoss RE, Hovig E (2004)
    Determination of hereditary mutations in the BRCA1 gene using archived serum samples and capillary electrophoresis
    Anal Chem, 76 (15), 4406-9
    DOI 10.1021/ac049788k, PubMed 15283579
  6. Gulliksen A, Solli L, Karlsen F, Rogne H, Hovig E, Nordstrøm T, Sirevåg R (2004)
    Real-time nucleic acid sequence-based amplification in nanoliter volumes
    Anal Chem, 76 (1), 9-14
    DOI 10.1021/ac034779h, PubMed 14697026
  7. Kuo WP, Kim EY, Trimarchi J, Jenssen TK, Vinterbo SA, Ohno-Machado L (2004)
    A primer on gene expression and microarrays for machine learning researchers
    J Biomed Inform, 37 (4), 293-303
    DOI 10.1016/j.jbi.2004.07.002, PubMed 15465482
  8. Kuo WP, Whipple ME, Epstein JB, Jenssen TK, Santos GS, Ohno-Machado L, Sonis ST (2004)
    Deciphering gene expression profiles generated from DNA microarrays and their applications in oral medicine
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 97 (5), 584-91
    DOI 10.1016/j.tripleo.2003.11.016, PubMed 15153870
  9. Liu F, Jenssen TK, Nygaard V, Sack J, Hovig E (2004)
    FigSearch: Using maximum entropy classifier to categorize biological figures
    2004 IEEE COMPUTATIONAL SYSTEMS BIOINFORMATICS CONFERENCE, PROCEEDINGS, 476-477
  10. Liu F, Jenssen TK, Nygaard V, Sack J, Hovig E (2004)
    FigSearch: a figure legend indexing and classification system
    Bioinformatics, 20 (16), 2880-2
    DOI 10.1093/bioinformatics/bth316, PubMed 15145804
  11. Lyng H, Badiee A, Svendsrud DH, Hovig E, Myklebost O, Stokke T (2004)
    Profound influence of microarray scanner characteristics on gene expression ratios: analysis and procedure for correction
    BMC Genomics, 5 (1), 10
    DOI 10.1186/1471-2164-5-10, PubMed 15018648
  12. Trøen G, Nygaard V, Jenssen TK, Ikonomou IM, Tierens A, Matutes E, Gruszka-Westwood A, Catovsky D, Myklebost O, Lauritzsen G, Hovig E, Delabie J (2004)
    Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma
    J Mol Diagn, 6 (4), 297-307
    DOI 10.1016/S1525-1578(10)60525-9, PubMed 15507668
  13. Wang X, Wang M, Amarzguioui M, Liu F, Fodstad Ø, Prydz H (2004)
    Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
    Int J Cancer, 112 (6), 994-1002
    DOI 10.1002/ijc.20527, PubMed 15386437

Publications 2003

  1. Andersen K, Smith-Sørensen B, Pedersen KB, Hovig E, Myklebost O, Fodstad Ø, Maelandsmo GM (2003)
    Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest
    Br J Cancer, 88 (12), 1995-2001
    DOI 10.1038/sj.bjc.6600998, PubMed 12799648
  2. Haslekås C, Grini PE, Nordgard SH, Thorstensen T, Viken MK, Nygaard V, Aalen RB (2003)
    ABI3 mediates expression of the peroxiredoxin antioxidant AtPER1 gene and induction by oxidative stress
    Plant Mol Biol, 53 (3), 313-26
    DOI 10.1023/b:plan.0000006937.21343.2a, PubMed 14750521
  3. Haslekås C, Viken MK, Grini PE, Nygaard V, Nordgard SH, Meza TJ, Aalen RB (2003)
    Seed 1-cysteine peroxiredoxin antioxidants are not involved in dormancy, but contribute to inhibition of germination during stress
    Plant Physiol, 133 (3), 1148-57
    DOI 10.1104/pp.103.025916, PubMed 14526116
  4. Kuo WP, Whipple ME, Jenssen TK, Todd R, Epstein JB, Ohno-Machado L, Sonis ST, Park PJ (2003)
    Microarrays and clinical dentistry
    J Am Dent Assoc, 134 (4), 456-62
    DOI 10.14219/jada.archive.2003.0195, PubMed 12733779
  5. Mathisen B, Lindstad RI, Hansen J, El-Gewely SA, Maelandsmo GM, Hovig E, Fodstad O, Loennechen T, Winberg JO (2003)
    S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells
    Clin Exp Metastasis, 20 (8), 701-11
    DOI 10.1023/B:CLIN.0000006819.21361.03, PubMed 14713104
  6. Nygaard V, Løland A, Holden M, Langaas M, Rue H, Liu F, Myklebost O, Fodstad Ø, Hovig E, Smith-Sørensen B (2003)
    Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
    BMC Genomics, 4 (1), 11
    DOI 10.1186/1471-2164-4-11, PubMed 12659661
  7. Tøstesen E, Liu F, Jenssen TK, Hovig E (2003)
    Speed-up of DNA melting algorithm with complete nearest neighbor properties
    Biopolymers, 70 (3), 364-76
    DOI 10.1002/bip.10495, PubMed 14579309
  8. Wang J, Bø TH, Jonassen I, Myklebost O, Hovig E (2003)
    Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data
    BMC Bioinformatics, 4, 60
    DOI 10.1186/1471-2105-4-60, PubMed 14651757
  9. Wang J, Myklebost O, Hovig E (2003)
    MGraph: graphical models for microarray data analysis
    Bioinformatics, 19 (17), 2210-1
    DOI 10.1093/bioinformatics/btg298, PubMed 14630649

Publications 2002

  1. Jenssen TK, Hovig E (2002)
    The semantic web and biology
    Drug Discov Today, 7 (19), 992
    DOI 10.1016/s1359-6446(02)02458-3, PubMed 12546914
  2. Jenssen TK, Kuo WP, Stokke T, Hovig E (2002)
    Associations between gene expressions in breast cancer and patient survival
    Hum Genet, 111 (4-5), 411-20
    DOI 10.1007/s00439-002-0804-5, PubMed 12384785
  3. Jenssen TK, Langaas M, Kuo WP, Smith-Sørensen B, Myklebost O, Hovig E (2002)
    Analysis of repeatability in spotted cDNA microarrays
    Nucleic Acids Res, 30 (14), 3235-44
    DOI 10.1093/nar/gkf441, PubMed 12136105
  4. Kuo WP, Jenssen TK, Butte AJ, Ohno-Machado L, Kohane IS (2002)
    Analysis of matched mRNA measurements from two different microarray technologies
    Bioinformatics, 18 (3), 405-12
    DOI 10.1093/bioinformatics/18.3.405, PubMed 11934739
  5. Kuo WP, Jenssen TK, Park PJ, Lingen MW, Hasina R, Ohno-Machado L (2002)
    Gene expression levels in different stages of progression in oral squamous cell carcinoma
    Proc AMIA Symp, 415-9
    PubMed 12474876
  6. Kuo WP, Whipple ME, Sonis ST, Ohno-Machado L, Jenssen TK (2002)
    Gene expression profiling by DNA microarrays and its application to dental research
    Oral Oncol, 38 (7), 650-6
    PubMed 12353490
  7. Ohno-Machado L, Vinterbo S, Dreiseitl S, Jenssen TK, Kuo W (2002)
    Comparing imperfect measurements with the Bland-Altman technique: application in gene expression analysis
    Proc AMIA Symp, 572-6
    PubMed 12463888
  8. Ree AH, Engebraaten O, Hovig E, Fodstad Ø (2002)
    Differential display analysis of breast carcinoma cells enriched by immunomagnetic target cell selection: gene expression profiles in bone marrow target cells
    Int J Cancer, 97 (1), 28-33
    DOI 10.1002/ijc.1564, PubMed 11774240
  9. Smith-Sørensen B, Lind GE, Skotheim RI, Fosså SD, Fodstad Ø, Stenwig AE, Jakobsen KS, Lothe RA (2002)
    Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancer
    Oncogene, 21 (57), 8878-84
    DOI 10.1038/sj.onc.1205978, PubMed 12483540
  10. Wang J, Nygaard V, Smith-Sørensen B, Hovig E, Myklebost O (2002)
    MArray: analysing single, replicated or reversed microarray experiments
    Bioinformatics, 18 (8), 1139-40
    DOI 10.1093/bioinformatics/18.8.1139, PubMed 12176840

Publications 2001

  1. Børresen-Dale AL, Hovig E, Smith-Sørensen B (2001)
    Detection of mutations by denaturing gradient gel electrophoresis
    Curr Protoc Hum Genet, Chapter 7, Unit 7.5
    DOI 10.1002/0471142905.hg0705s17, PubMed 18428306
  2. Hovig E, Maelandsmo G, Mellingsaeter T, Fodstad O, Mielewczyk SS, Wolfe J, Goodchild J (2001)
    Optimization of hammerhead ribozymes for the cleavage of S100A4 (CAPL) mRNA
    Antisense Nucleic Acid Drug Dev, 11 (2), 67-75
    DOI 10.1089/108729001750171272, PubMed 11334142
  3. Hovig E, Rye PD, Warren DJ, Nustad K (2001)
    CA 125: the end of the beginning
    Tumour Biol, 22 (6), 345-7
    DOI 10.1159/000050637, PubMed 11786728
  4. Jenssen TK, Laegreid A, Komorowski J, Hovig E (2001)
    A literature network of human genes for high-throughput analysis of gene expression
    Nat Genet, 28 (1), 21-8
    DOI 10.1038/88213, PubMed 11326270
  5. Komorowski J, Hvidsten TR, Jenssen TK, Tjeldvoll D, Hovig E, Laegreid A, Sandvik AK (2001)
    [New knowledge derived from measurement of gene expression with the DNA microarray method]
    Tidsskr Nor Laegeforen, 121 (10), 1229-32
    PubMed 11402750
  6. Lothe RA, Smith-Sørensen B, Hektoen M, Stenwig AE, Mandahl N, Saeter G, Mertens F (2001)
    Biallelic inactivation of TP53 rarely contributes to the development of malignant peripheral nerve sheath tumors
    Genes Chromosomes Cancer, 30 (2), 202-6
    DOI 10.1002/1098-2264(2000)9999:9999<::AID-GCC1079>3.3.CO;2-X, PubMed 11135438
  7. Møller P, Borg A, Heimdal K, Apold J, Vallon-Christersson J, Hovig E, Maehle L, Norwegian Inherited Breast Cancer Group, Norwegian Inherited Ovarian Cancer Group (2001)
    The BRCA1 syndrome and other inherited breast or breast-ovarian cancers in a Norwegian prospective series
    Eur J Cancer, 37 (8), 1027-32
    DOI 10.1016/s0959-8049(01)00075-2, PubMed 11334729
  8. Møller P, Heimdal K, Apold J, Fredriksen A, Borg A, Hovig E, Hagen A, Hagen B, Pedersen JC, Maehle L, Norwegian Inherited Breast Cancer Group, Norwegian Inherited Ovarian Cancer Group (2001)
    Genetic epidemiology of BRCA1 mutations in Norway
    Eur J Cancer, 37 (18), 2428-34
    DOI 10.1016/s0959-8049(01)00299-4, PubMed 11720839
  9. Warren W, Hovig E, Smith-Sørensen B, Børresen AL, Fujimura FK, Liu Q, Feng J, Sommer SS (2001)
    Detection of mutations by single-strand conformation polymorphism (SSCP) analysis and SSCP-hybrid methods
    Curr Protoc Hum Genet, Chapter 7, Unit 7.4
    DOI 10.1002/0471142905.hg0704s15, PubMed 18428305

Publications 2000

  1. Komorowski J, Hvidsten TR, Jenssen TK, Tjeldvoll D, Hovig E, Sandvik AK, Laegreid A (2000)
    Towards Knowledge Discovery from cDNA Microarray Gene Expression Data
    Lect. Notes Comput. Sci., 1910, 470-475

Publications 1999

  1. Bjørnland K, Winberg JO, Odegaard OT, Hovig E, Loennechen T, Aasen AO, Fodstad O, Maelandsmo GM (1999)
    S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme
    Cancer Res, 59 (18), 4702-8
    PubMed 10493528
  2. Borg A, Dørum A, Heimdal K, Maehle L, Hovig E, Møller P (1999)
    BRCA1 1675delA and 1135insA account for one third of Norwegian familial breast-ovarian cancer and are associated with later disease onset than less frequent mutations
    Dis Markers, 15 (1-3), 79-84
    DOI 10.1155/1999/278269, PubMed 10595257
  3. Danielsen T, Smith-Sørensen B, Grønlund HA, Hvidsten M, Børresen-Dale AL, Rofstad EK (1999)
    No association between radiosensitivity and TP53 status, G1 arrest or protein levels of p53, myc, ras or raf in human melanoma lines
    Int J Radiat Biol, 75 (9), 1149-60
    DOI 10.1080/095530099139629, PubMed 10528923
  4. Dørum A, Heimdal K, Hovig E, Inganäs M, Møller P (1999)
    Penetrances of BRCA1 1675delA and 1135insA with respect to breast cancer and ovarian cancer
    Am J Hum Genet, 65 (3), 671-9
    DOI 10.1086/302530, PubMed 10441573
  5. Dørum A, Hovig E, Tropé C, Inganas M, Møller P (1999)
    Three per cent of Norwegian ovarian cancers are caused by BRCA1 1675delA or 1135insA
    Eur J Cancer, 35 (5), 779-81
    DOI 10.1016/s0959-8049(99)00050-7, PubMed 10505039
  6. Lonning PE, Johnsen H, Geisler S, Aas T, Smith-Sorensen B, Akslen LA, Borresen-Dale AL (1999)
    TP53 as a predictor of response to chemotherapy in breast cancer
    ESO SCI UPDATES, 4, 73-88
  7. Ree AH, Tvermyr M, Engebraaten O, Rooman M, Røsok O, Hovig E, Meza-Zepeda LA, Bruland OS, Fodstad O (1999)
    Expression of a novel factor in human breast cancer cells with metastatic potential
    Cancer Res, 59 (18), 4675-80
    PubMed 10493524
  8. Ruud P, Fodstad O, Hovig E (1999)
    Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells
    Int J Cancer, 80 (1), 119-25
    DOI 10.1002/(sici)1097-0215(19990105)80:1<119::aid-ijc22>3.0.co;2-x, PubMed 9935241
  9. Wacey AI, Cooper DN, Liney D, Hovig E, Krawczak M (1999)
    Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53
    Hum Genet, 104 (1), 15-22
    DOI 10.1007/s004390050904, PubMed 10071187

Publications 1998

  1. Andersen K, Maelandsmo GM, Hovig E, Fodstad O, Loennechen T, Winberg JO (1998)
    Interleukin-1 alpha and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL
    Anticancer Res, 18 (5A), 3299-303
    PubMed 9858899
  2. Prasmickaite L, Hogset A, Maelandsmo G, Berg K, Goodchild J, Perkins T, Fodstad O, Hovig E (1998)
    Intracellular metabolism of a 2'-O-methyl-stabilized ribozyme after uptake by DOTAP transfection or asfree ribozyme. A study by capillary electrophoresis
    Nucleic Acids Res, 26 (18), 4241-8
    DOI 10.1093/nar/26.18.4241, PubMed 9722645

Publications 1997

  1. de Graaf H, Maelandsmo GM, Ruud P, Forus A, Oyjord T, Fodstad O, Hovig E (1997)
    Ectopic expression of target genes may represent an inherent limitation of RT-PCR assays used for micrometastasis detection: studies on the epithelial glycoprotein gene EGP-2
    Int J Cancer, 72 (1), 191-6
    DOI 10.1002/(sici)1097-0215(19970703)72:1<191::aid-ijc27>3.0.co;2-l, PubMed 9212242
  2. Dørum A, Møller P, Kamsteeg EJ, Scheffer H, Burton M, Heimdal KR, Maehle LO, Hovig E, Tropé CG, van der Hout AH, van der Meulen MA, Buys CH, te Meerman GJ (1997)
    A BRCA1 founder mutation, identified with haplotype analysis, allowing genotype/phenotype determination and predictive testing
    Eur J Cancer, 33 (14), 2390-2
    DOI 10.1016/s0959-8049(97)00328-6, PubMed 9616287
  3. Hainaut P, Soussi T, Shomer B, Hollstein M, Greenblatt M, Hovig E, Harris CC, Montesano R (1997)
    Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects
    Nucleic Acids Res, 25 (1), 151-7
    DOI 10.1093/nar/25.1.151, PubMed 9016527
  4. Maelandsmo GM, Flørenes VA, Mellingsaeter T, Hovig E, Kerbel RS, Fodstad O (1997)
    Differential expression patterns of S100A2, S100A4 and S100A6 during progression of human malignant melanoma
    Int J Cancer, 74 (4), 464-9
    DOI 10.1002/(sici)1097-0215(19970822)74:4<464::aid-ijc19>3.0.co;2-9, PubMed 9291441

Publications 1996

  1. Hollstein M, Shomer B, Greenblatt M, Soussi T, Hovig E, Montesano R, Harris CC (1996)
    Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation
    Nucleic Acids Res, 24 (1), 141-6
    DOI 10.1093/nar/24.1.141, PubMed 8594564
  2. Hovig E, Fodstad O (1996)
    [Prostate-specific membrane antigen]
    Tidsskr Nor Laegeforen, 116 (3), 411-2
    PubMed 8638273
  3. Maelandsmo GM, Flørenes VA, Hovig E, Oyjord T, Engebraaten O, Holm R, Børresen AL, Fodstad O (1996)
    Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas
    Br J Cancer, 73 (8), 909-16
    DOI 10.1038/bjc.1996.181, PubMed 8611425
  4. Maelandsmo GM, Hovig E, Skrede M, Engebraaten O, Flørenes VA, Myklebost O, Grigorian M, Lukanidin E, Scanlon KJ, Fodstad O (1996)
    Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts1) ribozyme
    Cancer Res, 56 (23), 5490-8
    PubMed 8968106
  5. Smith-Sørensen B, Hovig E (1996)
    CDKN2A (p16INK4A) somatic and germline mutations
    Hum Mutat, 7 (4), 294-303
    DOI 10.1002/(SICI)1098-1004(1996)7:4<294::AID-HUMU2>3.0.CO;2-9, PubMed 8723678
  6. Aas T, Børresen AL, Geisler S, Smith-Sørensen B, Johnsen H, Varhaug JE, Akslen LA, Lønning PE (1996)
    Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients
    Nat Med, 2 (7), 811-4
    DOI 10.1038/nm0796-811, PubMed 8673929

Publications 1995

  1. Deggerdal AH, Pettersen F, Kvalheim G, Hornes E, Smeland E, Fodstad O, Hovig E (1995)
    Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
    Lab Invest, 72 (4), 411-8
    PubMed 7723279
  2. Krawczak M, Smith-Sorensen B, Schmidtke J, Kakkar VV, Cooper DN, Hovig E (1995)
    Somatic spectrum of cancer-associated single basepair substitutions in the TP53 gene is determined mainly by endogenous mechanisms of mutation and by selection
    Hum Mutat, 5 (1), 48-57
    DOI 10.1002/humu.1380050107, PubMed 7728149
  3. Maelandsmo GM, Berner JM, Flørenes VA, Forus A, Hovig E, Fodstad O, Myklebost O (1995)
    Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1
    Br J Cancer, 72 (2), 393-8
    DOI 10.1038/bjc.1995.344, PubMed 7640224

Publications 1994

  1. Hollstein M, Rice K, Greenblatt MS, Soussi T, Fuchs R, Sørlie T, Hovig E, Smith-Sørensen B, Montesano R, Harris CC (1994)
    Database of p53 gene somatic mutations in human tumors and cell lines
    Nucleic Acids Res, 22 (17), 3551-5
    PubMed 7937055
  2. McIntyre JF, Smith-Sorensen B, Friend SH, Kassell J, Borresen AL, Yan YX, Russo C, Sato J, Barbier N, Miser J (1994)
    Germline mutations of the p53 tumor suppressor gene in children with osteosarcoma
    J Clin Oncol, 12 (5), 925-30
    DOI 10.1200/JCO.1994.12.5.925, PubMed 8164043

Publications 1993

  1. Andreassen A, Oyjord T, Hovig E, Holm R, Flørenes VA, Nesland JM, Myklebost O, Høie J, Bruland OS, Børresen AL (1993)
    p53 abnormalities in different subtypes of human sarcomas
    Cancer Res, 53 (3), 468-71
    PubMed 8425179

Publications 1992

  1. Børresen AL, Andersen TI, Garber J, Barbier-Piraux N, Thorlacius S, Eyfjörd J, Ottestad L, Smith-Sørensen B, Hovig E, Malkin D (1992)
    Screening for germ line TP53 mutations in breast cancer patients
    Cancer Res, 52 (11), 3234-6
    PubMed 1591732
  2. Hovig E, Smith-Sørensen B, Gebhardt MC, Ryberg D, Lothe R, Børresen AL (1992)
    No alterations in exon 21 of the RB1 gene in sarcomas and carcinomas of the breast, colon, and lung
    Genes Chromosomes Cancer, 5 (2), 97-103
    DOI 10.1002/gcc.2870050202, PubMed 1381957
  3. Hovig E, Smith-Sørensen B, Uitterlinden AG, Børresen AL (1992)
    Detection of DNA variation in cancer
    Pharmacogenetics, 2 (6), 317-28
    DOI 10.1097/00008571-199212000-00011, PubMed 1306133
  4. Smith-Sørensen B, Hovig E, Andersson B, Børresen AL (1992)
    Screening for mutations in human HPRT cDNA using the polymerase chain reaction (PCR) in combination with constant denaturant gel electrophoresis (CDGE)
    Mutat Res, 269 (1), 41-53
    DOI 10.1016/0027-5107(92)90159-y, PubMed 1381470

Publications 1991

  1. Alfsen GC, Beiske K, Holte H, Hovig E, Deggerdal A, Sandlie I, Widing E, Slørdahl S, Klepper LK, Sizoo W (1991)
    T-cell receptor tau delta +/CD3+4-8-T- cell acute lymphoblastic leukemias: a distinct subgroup of leukemias in children. A report of five cases
    Blood, 77 (9), 2023-30
    PubMed 1826854
  2. Børresen AL, Hovig E, Smith-Sørensen B, Malkin D, Lystad S, Andersen TI, Nesland JM, Isselbacher KJ, Friend SH (1991)
    Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations
    Proc Natl Acad Sci U S A, 88 (19), 8405-9
    DOI 10.1073/pnas.88.19.8405, PubMed 1924299
  3. Hovig, Eivind, Smith-Sørensen B, Brøgger A, Børrensen AL (1991)
    Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
    Mutat Res, 263 (1), 61
    DOI 10.1016/0165-7992(91)90036-4, PubMed 2034242
  4. Hovig E, Smith-Sørensen B, Brøgger A, Børresen AL (1991)
    Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
    Mutat Res, 262 (1), 63-71
    DOI 10.1016/0165-7992(91)90108-g, PubMed 1702518

Publications 1990

  1. BORRESEN AL, HOVIG E, SMITHSORENSEN B, VRIELING H, APOLD J, BROGGER A (1990)
    SCREENING FOR BASE MUTATIONS IN THE PAH AND HPRT LOCI USING THE POLYMERASE CHAIN-REACTION (PCR) IN COMBINATION WITH DENATURING GRADIENT GEL-ELECTROPHORESIS (DGGE)
    Prog.Clin.Biol.Res., 340, 389-398
  2. Børresen AL, Hovig E, Smith-Sørensen B, Vrieling H, Apold J, Brøgger A (1990)
    Screening for base mutations in the PAH and HPRT loci using the polymerase chain reaction (PCR) in combination with denaturing gradient gel electrophoresis (DGGE)
    Prog Clin Biol Res, 340A, 389-98
    PubMed 2388921

Publications 1989

  1. OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
    FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
    J. Biol. Chem., 264 (22), 12749-12751
  2. Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
    Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
    J Biol Chem, 264 (22), 12747-51
    PubMed 2753882

Publications 1988

  1. Børresen AL, Hovig E, Brøgger A (1988)
    Detection of base mutations in genomic DNA using denaturing gradient gel electrophoresis (DGGE) followed by transfer and hybridization with gene-specific probes
    Mutat Res, 202 (1), 77-83
    DOI 10.1016/0027-5107(88)90166-2, PubMed 2903443

Publications 1987

  1. Hovig E, Winberg JO, Fodstad O, Brøgger A, Gedde-Dahl T (1987)
    Chromosome 13 instability and esterase D expression in an osteosarcoma cell line
    Cancer Genet Cytogenet, 24 (2), 327-34
    DOI 10.1016/0165-4608(87)90115-4, PubMed 2878716
 
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