Publications

Publications published since 1987 from OUS - Metastasis - molecular studies and development of methods

163 publications found

Publications 2020

  1. Ahadova A, Seppälä TT, Engel C, Gallon R, Burn J, Holinski-Feder E, Steinke-Lange V, Möslein G, Nielsen M, Ten Broeke SW, Laghi L, Dominguez-Valentin M, Capella G, Macrae F, Scott R, Hüneburg R, Nattermann J, Hoffmeister M, Brenner H, Bläker H, von Knebel Doeberitz M, Sampson JR, Vasen H, Mecklin JP, Møller P et al. (2020)
    The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance
    Int J Cancer
    DOI 10.1002/ijc.33224, PubMed 32683684
  2. Álvarez K, Orellana P, De la Fuente M, Canales T, Pinto E, Heine C, Solar B, Hurtado C, Møller P, Kronberg U, Zarate AJ, Dominguez-Valentin M, López-Köstner F (2020)
    Spectrum and Frequency of Tumors, Cancer Risk and Survival in Chilean Families with Lynch Syndrome: Experience of the Implementation of a Registry
    J Clin Med, 9 (6)
    DOI 10.3390/jcm9061861, PubMed 32549215
  3. Arstad C, Taskén K, Refinetti P, Axcrona U, Giercksky KE, Ekstrøm PO (2020)
    Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer
    Prostate Cancer, 2020, 7673684
    DOI 10.1155/2020/7673684, PubMed 32908706
  4. Dominguez-Valentin M, Sampson JR, Møller P, Seppälä TT, PLSD Collaborators (2020)
    Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum
    Int J Cancer
    DOI 10.1002/ijc.33214, PubMed 32783184
  5. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2020)
    Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med, 22 (9), 1569
    DOI 10.1038/s41436-020-0892-4, PubMed 32690931
  6. Dominguez-Valentin M, Seppälä TT, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W, Vangala D et al. (2020)
    Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database
    J Clin Med, 9 (7)
    DOI 10.3390/jcm9072290, PubMed 32708519
  7. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D132-D141
    DOI 10.1093/nar/gkz885, PubMed 31598695
  8. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D1172
    DOI 10.1093/nar/gkz1016, PubMed 31642479
  9. Humbert M, Morán M, de la Cruz-Ojeda P, Muntané J, Wiedmer T, Apostolova N, McKenna SL, Velasco G, Balduini W, Eckhart L, Janji B, Sampaio-Marques B, Ludovico P, Žerovnik E, Langer R, Perren A, Engedal N, Tschan MP (2020)
    Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot
    Biology (Basel), 9 (3)
    DOI 10.3390/biology9030059, PubMed 32245178
  10. Itkonen HM, Poulose N, Steele RE, Martin SES, Levine ZG, Duveau DY, Carelli R, Singh R, Urbanucci A, Loda M, Thomas CJ, Mills IG, Walker S (2020)
    Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9
    Mol Cancer Res (in press)
    DOI 10.1158/1541-7786.MCR-20-0339, PubMed 32611550
  11. Kohvakka A, Sattari M, Shcherban A, Annala M, Urbanucci A, Kesseli J, Tammela TLJ, Kivinummi K, Latonen L, Nykter M, Visakorpi T (2020)
    AR and ERG drive the expression of prostate cancer specific long noncoding RNAs
    Oncogene, 39 (30), 5241-5251
    DOI 10.1038/s41388-020-1365-6, PubMed 32555329
  12. Kotsopoulos J, Karlan B, Gronwald J, Hall E, Moller P, Tung N, Zakalik D, Foulkes WD, Rosen B, Neuhausen SL, Sun P, Lubinksi J, Narod SA (2020)
    Long-term outcomes following a diagnosis of ovarian cancer at the time of preventive oophorectomy among BRCA1 and BRCA2 mutation carriers
    Int J Gynecol Cancer, 30 (6), 825-830
    DOI 10.1136/ijgc-2019-001141, PubMed 32354794
  13. Lavelle TJ, Alver TN, Heintz KM, Wernhoff P, Nygaard V, Nakken S, Øy GF, Bøe SL, Urbanucci A, Hovig E (2020)
    Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes
    Cancers (Basel), 12 (7)
    DOI 10.3390/cancers12071719, PubMed 32605315
  14. Møller P (2020)
    The Prospective Lynch Syndrome Database reports enable evidence-based personal precision health care
    Hered Cancer Clin Pract, 18, 6
    DOI 10.1186/s13053-020-0138-0, PubMed 32190163
  15. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2020)
    Correction: Møller, P.; et al. Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift. Cancers 2019, 11, 132
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020410, PubMed 32050665
  16. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2020)
    Recent advances in Lynch syndrome
    Fam Cancer
    DOI 10.1007/s10689-020-00200-6, PubMed 32770425
  17. Olafsdottir EJ, Borg A, Jensen MB, Gerdes AM, Johansson ALV, Barkardottir RB, Johannsson OT, Ejlertsen B, Sønderstrup IMH, Hovig E, Lænkholm AV, Hansen TVO, Olafsdottir GH, Rossing M, Jonasson JG, Sigurdsson S, Loman N, Nilsson MP, Narod SA, Tryggvadottir L (2020)
    Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
    Br J Cancer (in press)
    DOI 10.1038/s41416-020-01056-4, PubMed 32939053
  18. Pace M, Falappa M, Freschi A, Balzani E, Berteotti C, Lo Martire V, Kaveh F, Hovig E, Zoccoli G, Amici R, Cerri M, Urbanucci A, Tucci V (2020)
    Loss of Snord116 impacts lateral hypothalamus, sleep, and food-related behaviors
    JCI Insight, 5 (12)
    DOI 10.1172/jci.insight.137495, PubMed 32365348
  19. Piñero TA, Soukarieh O, Rolain M, Alvarez K, López-Köstner F, Torrezan GT, Carraro DM, De Oliveira Nascimento IL, Bomfim TF, Machado-Lopes TMB, Freitas JC, Toralles MB, Sandes KA, Rossi BM, Junior SA, Meira J, Dominguez-Valentin M, Møller P, Vaccaro CA, Martins A, Pavicic WH (2020)
    MLH1 intronic variants mapping to + 5 position of splice donor sites lead to deleterious effects on RNA splicing
    Fam Cancer, 19 (4), 323-336
    DOI 10.1007/s10689-020-00182-5, PubMed 32363481
  20. Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
    Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
    Acta Oncol, 59 (7), 733-740
    DOI 10.1080/0284186X.2020.1742377, PubMed 32208873
  21. Seppälä TT, Dominguez-Valentin M, Sampson JR, Møller P (2020)
    Prospective observational data informs understanding and future management of Lynch syndrome: insights from the Prospective Lynch Syndrome Database (PLSD)
    Fam Cancer
    DOI 10.1007/s10689-020-00193-2, PubMed 32507935
  22. Seppälä TT, Latchford A, Negoi I, Sampaio Soares A, Jimenez-Rodriguez R, Sánchez-Guillén L, Evans DG, Ryan N, Crosbie EJ, Dominguez-Valentin M, Burn J, Kloor M, von Knebel Doeberitz M, van Duijnhoven FJB, Quirke P, Sampson JR, Møller P, Möslein G, European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP) (2020)
    European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
    Br J Surg (in press)
    DOI 10.1002/bjs.11902, PubMed 32956497
  23. Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
    Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
    J Biomed Nanotechnol, 16 (4), 432-445
    DOI 10.1166/jbn.2020.2906, PubMed 32970976
  24. Wise JF, Nakken S, Steen CB, Vodák D, Trøen G, Johannessen B, Lingjærde OC, Hilden V, Blaker YN, Bai B, Aasheim LB, Pasanen A, Lorenz S, Sveen A, Lothe RA, Myklebost O, Leppä S, Meza-Zepeda LA, Beiske K, Lawrence MS, Hovig E, Myklebust JH, Smeland EB, Holte H (2020)
    Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
    Blood Adv, 4 (9), 1859-1866
    DOI 10.1182/bloodadvances.2019001325, PubMed 32374878
  25. Waaler J, Mygland L, Tveita A, Strand MF, Solberg NT, Olsen PA, Aizenshtadt A, Fauskanger M, Lund K, Brinch SA, Lycke M, Dybing E, Nygaard V, Bøe SL, Heintz KM, Hovig E, Hammarström C, Corthay A, Krauss S (2020)
    Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
    Commun Biol, 3 (1), 196
    DOI 10.1038/s42003-020-0916-2, PubMed 32332858

Publications 2019

  1. Braadland PR, Ramberg H, Grytli HH, Urbanucci A, Nielsen HK, Guldvik IJ, Engedal A, Ketola K, Wang W, Svindland A, Mills IG, Bjartell A, Taskén KA (2019)
    The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells
    Mol Cancer Res, 17 (11), 2154-2168
    DOI 10.1158/1541-7786.MCR-18-0605, PubMed 31395667
  2. Braadland PR, Urbanucci A (2019)
    Chromatin reprogramming as an adaptation mechanism in advanced prostate cancer
    Endocr Relat Cancer, 26 (4), R211-R235
    DOI 10.1530/ERC-18-0579, PubMed 30844748
  3. Crosbie EJ, Ryan NAJ, Arends MJ, Bosse T, Burn J, Cornes JM, Crawford R, Eccles D, Frayling IM, Ghaem-Maghami S, Hampel H, Kauff ND, Kitchener HC, Kitson SJ, Manchanda R, McMahon RFT, Monahan KJ, Menon U, Møller P, Möslein G, Rosenthal A, Sasieni P, Seif MW, Singh N, Skarrott P et al. (2019)
    The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome
    Genet Med, 21 (10), 2390-2400
    DOI 10.1038/s41436-019-0489-y, PubMed 30918358
  4. Della Valle A, Rossi BM, Palmero EI, Antelo M, Vaccaro CA, López-Kostner F, Alvarez K, Cruz-Correa M, Bruno LI, Forones NM, Mindiola JAR, Buleje J, Spirandelli F, Bohorquez M, Cock-Rada AM, Sullcahuaman Y, Nascimento I, Abe-Sandes K, Lino-Silva LS, Petracchi F, Mampel A, Rodriguez Y, Rossi NT, Yañez CB, Rubio C et al. (2019)
    A snapshot of current genetic testing practice in Lynch syndrome: The results of a representative survey of 33 Latin American existing centres/registries
    Eur J Cancer, 119, 112-121
    DOI 10.1016/j.ejca.2019.07.017, PubMed 31442815
  5. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Holth A, Capella G, Davidson B, Evans DG, Martins A, Møller P, Hovig E (2019)
    Results of multigene panel testing in familial cancer cases without genetic cause demonstrated by single gene testing
    Sci Rep, 9 (1), 18555
    DOI 10.1038/s41598-019-54517-z, PubMed 31811167
  6. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2019)
    Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med, 22 (1), 15-25
    DOI 10.1038/s41436-019-0596-9, PubMed 31337882
  7. Dominguez-Valentin M, Seppälä TT, Sampson JR, Macrae F, Winship I, Evans DG, Scott RJ, Burn J, Möslein G, Bernstein I, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lindblom A, Plazzer JP, Tjandra D, Thomas H, Green K, Lalloo F, Crosbie EJ, Hill J, Capella G, Pineda M, Navarro M, Vidal JB et al. (2019)
    Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report
    Hered Cancer Clin Pract, 17, 28
    DOI 10.1186/s13053-019-0127-3, PubMed 31636762
  8. Handle F, Prekovic S, Helsen C, Van den Broeck T, Smeets E, Moris L, Eerlings R, Kharraz SE, Urbanucci A, Mills IG, Joniau S, Attard G, Claessens F (2019)
    Drivers of AR indifferent anti-androgen resistance in prostate cancer cells
    Sci Rep, 9 (1), 13786
    DOI 10.1038/s41598-019-50220-1, PubMed 31551480
  9. Itkonen HM, Urbanucci A, Martin SE, Khan A, Mathelier A, Thiede B, Walker S, Mills IG (2019)
    High OGT activity is essential for MYC-driven proliferation of prostate cancer cells
    Theranostics, 9 (8), 2183-2197
    DOI 10.7150/thno.30834, PubMed 31149037
  10. Kanduri C, Bock C, Gundersen S, Hovig E, Sandve GK (2019)
    Colocalization analyses of genomic elements: approaches, recommendations and challenges
    Bioinformatics, 35 (9), 1615-1624
    DOI 10.1093/bioinformatics/bty835, PubMed 30307532
  11. Kotsopoulos J, Lubinski J, Lynch HT, Tung N, Armel S, Senter L, Singer CF, Fruscio R, Couch F, Weitzel JN, Karlan B, Foulkes WD, Moller P, Eisen A, Ainsworth P, Neuhausen SL, Olopade O, Sun P, Gronwald J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2019)
    Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 175 (2), 443-449
    DOI 10.1007/s10549-019-05162-7, PubMed 30756284
  12. Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
    Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
    Cold Spring Harb Mol Case Stud, 5 (2)
    DOI 10.1101/mcs.a003566, PubMed 30862609
  13. Metcalfe K, Eisen A, Senter L, Armel S, Bordeleau L, Meschino WS, Pal T, Lynch HT, Tung NM, Kwong A, Ainsworth P, Karlan B, Moller P, Eng C, Weitzel JN, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2019)
    International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation
    Br J Cancer, 121 (1), 15-21
    DOI 10.1038/s41416-019-0446-1, PubMed 30971774
  14. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2019)
    Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift
    Cancers (Basel), 11 (2)
    DOI 10.3390/cancers11020132, PubMed 30678073
  15. Njølstad PR, Andreassen OA, Brunak S, Børglum AD, Dillner J, Esko T, Franks PW, Freimer N, Groop L, Heimer H, Hougaard DM, Hovig E, Hveem K, Jalanko A, Kaprio J, Knudsen GP, Melbye M, Metspalu A, Mortensen PB, Palmgren J, Palotie A, Reed W, Stefánsson H, Stitziel NO, Sullivan PF et al. (2019)
    Roadmap for a precision-medicine initiative in the Nordic region
    Nat Genet, 51 (6), 924-930
    DOI 10.1038/s41588-019-0391-1, PubMed 30988515
  16. Nygård S, Lingjærde OC, Caldas C, Hovig E, Børresen-Dale AL, Helland Å, Haakensen VD (2019)
    PathTracer: High-sensitivity detection of differential pathway activity in tumours
    Sci Rep, 9 (1), 16332
    DOI 10.1038/s41598-019-52529-3, PubMed 31704995
  17. Pashov A, Shivarov V, Hadzhieva M, Kostov V, Ferdinandov D, Heintz KM, Pashova S, Todorova M, Vassilev T, Kieber-Emmons T, Meza-Zepeda LA, Hovig E (2019)
    Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries
    Front Immunol, 10, 2796
    DOI 10.3389/fimmu.2019.02796, PubMed 31849974
  18. Ree AH, Nygaard V, Russnes HG, Heinrich D, Nygaard V, Johansen C, Bergheim IR, Hovig E, Beiske K, Negård A, Børresen-Dale AL, Flatmark K, Mælandsmo GM (2019)
    Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
    Cancer Immunol Res, 7 (5), 701-706
    DOI 10.1158/2326-6066.CIR-18-0777, PubMed 30804006
  19. Sampson JR, Dominguez-Valentin M, Seppälä TT, Møller P (2019)
    Response to Tolva et al
    Genet Med, 22 (4), 813-814
    DOI 10.1038/s41436-019-0717-5, PubMed 31801985
  20. Seppälä TT, Ahadova A, Dominguez-Valentin M, Macrae F, Evans DG, Therkildsen C, Sampson J, Scott R, Burn J, Möslein G, Bernstein I, Holinski-Feder E, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lautrup CK, Lindblom A, Plazzer JP, Winship I, Tjandra D, Katz LH, Aretz S, Hüneburg R, Holzapfel S, Heinimann K et al. (2019)
    Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report
    Hered Cancer Clin Pract, 17, 8
    DOI 10.1186/s13053-019-0106-8, PubMed 30858900
  21. Ten Broeke SW, Rodríguez-Girondo M, Suerink M, Aretz S, Bernstein I, Capellá G, Engel C, Gomez-Garcia EB, van Hest LP, von Knebel Doeberitz M, Lagerstedt-Robinson K, Letteboer TGW, Moller P, van Os TA, Pineda M, Rahner N, Olderode-Berends MJW, von Salomé J, Schackert HK, Spruijt L, Steinke-Lange V, Wagner A, Tops CMJ, Nielsen M (2019)
    The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect
    Cancer Epidemiol Biomarkers Prev, 28 (6), 1010-1014
    DOI 10.1158/1055-9965.EPI-18-0576, PubMed 30824524
  22. Tolios A, De Las Rivas J, Hovig E, Trouillas P, Scorilas A, Mohr T (2019)
    Computational approaches in cancer multidrug resistance research: Identification of potential biomarkers, drug targets and drug-target interactions
    Drug Resist Updat, 48, 100662
    DOI 10.1016/j.drup.2019.100662, PubMed 31927437

Publications 2018

  1. Birkeland E, Zhang S, Poduval D, Geisler J, Nakken S, Vodak D, Meza-Zepeda LA, Hovig E, Myklebost O, Knappskog S, Lønning PE (2018)
    Patterns of genomic evolution in advanced melanoma
    Nat Commun, 9 (1), 2665
    DOI 10.1038/s41467-018-05063-1, PubMed 29991680
  2. Dominguez-Valentin M, Evans DGR, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds
    Hered Cancer Clin Pract, 16, 4
    DOI 10.1186/s13053-018-0086-0, PubMed 29371908
  3. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families
    Fam Cancer, 17 (1), 141-153
    DOI 10.1007/s10689-017-0011-0, PubMed 28608266
  4. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Identification of genetic variants for clinical management of familial colorectal tumors
    BMC Med Genet, 19 (1), 26
    DOI 10.1186/s12881-018-0533-9, PubMed 29458332
  5. Ebenesersdóttir SS, Sandoval-Velasco M, Gunnarsdóttir ED, Jagadeesan A, Guðmundsdóttir VB, Thordardóttir EL, Einarsdóttir MS, Moore KHS, Sigurðsson Á, Magnúsdóttir DN, Jónsson H, Snorradóttir S, Hovig E, Møller P, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Cavalleri GL, Gilbert E, Lalueza-Fox C, Walser JW, Kristjánsdóttir S, Gopalakrishnan S et al. (2018)
    Ancient genomes from Iceland reveal the making of a human population
    Science, 360 (6392), 1028-1032
    DOI 10.1126/science.aar2625, PubMed 29853688
  6. Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, Olopade O, Zakalik D, Lubinski J, Narod SA, Kotsopoulos J, (2018)
    Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers
    Int J Epidemiol, 47 (3), 987-997
    DOI 10.1093/ije/dyy039, PubMed 29547931
  7. Kotsopoulos J, Gronwald J, Karlan B, Rosen B, Huzarski T, Moller P, Lynch HT, Singer CF, Senter L, Neuhausen SL, Tung N, Eisen A, Foulkes WD, Ainsworth P, Sun P, Lubinski J, Narod SA, Hereditary Ovarian Cancer Clinical Study Group (2018)
    Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 150 (1), 85-91
    DOI 10.1016/j.ygyno.2018.05.011, PubMed 29793803
  8. Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2018)
    Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers
    JAMA Oncol, 4 (8), 1059-1065
    DOI 10.1001/jamaoncol.2018.0211, PubMed 29710224
  9. Møller P, Hovig E (2018)
    Retraction Note to: The BRCA2 variant c.68-7 T > A is associated with breast cancer
    Hered Cancer Clin Pract, 16, 10
    DOI 10.1186/s13053-018-0093-1, PubMed 29745381
  10. Ten Broeke SW, van der Klift HM, Tops CMJ, Aretz S, Bernstein I, Buchanan DD, de la Chapelle A, Capella G, Clendenning M, Engel C, Gallinger S, Gomez Garcia E, Figueiredo JC, Haile R, Hampel HL, Hopper JL, Hoogerbrugge N, von Knebel Doeberitz M, Le Marchand L, Letteboer TGW, Jenkins MA, Lindblom A, Lindor NM, Mensenkamp AR, Møller P et al. (2018)
    Cancer Risks for PMS2-Associated Lynch Syndrome
    J Clin Oncol, 36 (29), 2961-2968
    DOI 10.1200/JCO.2018.78.4777, PubMed 30161022
  11. Vaccaro CA, López-Kostner F, Adriana DV, Palmero EI, Rossi BM, Antelo M, Solano A, Carraro DM, Forones NM, Bohorquez M, Lino-Silva LS, Buleje J, Spirandelli F, Abe-Sandes K, Nascimento I, Sullcahuaman Y, Sarroca C, Gonzalez ML, Herrando AI, Alvarez K, Neffa F, Galvão HC, Esperon P, Golubicki M, Cisterna D et al. (2018)
    From colorectal cancer pattern to the characterization of individuals at risk: Picture for genetic research in Latin America
    Int J Cancer, 145 (2), 318-326
    DOI 10.1002/ijc.31920, PubMed 30303536
  12. Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
    Sample-Index Misassignment Impacts Tumour Exome Sequencing
    Sci Rep, 8 (1), 5307
    DOI 10.1038/s41598-018-23563-4, PubMed 29593270

Publications 2017

  1. Arstad C, Refinetti P, Kristensen AT, Giercksky KE, Ekstrøm PO (2017)
    Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?
    BMC Cancer, 17 (1), 406
    DOI 10.1186/s12885-017-3365-7, PubMed 28592327
  2. Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
    Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
    Curr Pharm Des, 23 (32), 4716-4725
    DOI 10.2174/1381612823666170710154936, PubMed 28699527
  3. Domanska D, Vodák D, Lund-Andersen C, Salvatore S, Hovig E, Sandve GK (2017)
    The rainfall plot: its motivation, characteristics and pitfalls
    BMC Bioinformatics, 18 (1), 264
    DOI 10.1186/s12859-017-1679-8, PubMed 28521741
  4. Helland Å, Brustugun OT, Nakken S, Halvorsen AR, Dønnem T, Bremnes R, Busund LT, Sun J, Lorenz S, Solberg SK, Jørgensen LH, Vodak D, Myklebost O, Hovig E, Meza-Zepeda LA (2017)
    High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival
    Int J Cancer, 141 (1), 184-190
    DOI 10.1002/ijc.30726, PubMed 28387924
  5. Kanduri C, Domanska D, Hovig E, Sandve GK (2017)
    Genome build information is an essential part of genomic track files
    Genome Biol, 18 (1), 175
    DOI 10.1186/s13059-017-1312-1, PubMed 28911336
  6. Meisal R, Rounge TB, Christiansen IK, Eieland AK, Worren MM, Molden TF, Kommedal Ø, Hovig E, Leegaard TM, Ambur OH (2017)
    HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
    PLoS One, 12 (1), e0169074
    DOI 10.1371/journal.pone.0169074, PubMed 28045981
  7. Møller P, Hovig E (2017)
    The BRCA2 variant c.68-7 T>A is associated with breast cancer
    Hered Cancer Clin Pract, 15, 20 (Retracted)
    DOI 10.1186/s13053-017-0080-y, PubMed 29158857
  8. Møller P, Seppälä TT, Bernstein I, Holinski-Feder E, Sala P, Gareth Evans D, Lindblom A, Macrae F, Blanco I, Sijmons RH, Jeffries J, Vasen HFA, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen JT, Jenkins MA, Green K, Lalloo F, Sunde L, Mints M et al. (2017)
    Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
    Gut, 67 (7), 1306-1316
    DOI 10.1136/gutjnl-2017-314057, PubMed 28754778
  9. Namløs HM, Zaikova O, Bjerkehagen B, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2017)
    Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report
    BMC Cancer, 17 (1), 29
    DOI 10.1186/s12885-016-2992-8, PubMed 28061772
  10. Nygaard V, Rødland EA, Hovig E (2017)
    Reply to Towfic and others' letter to the editor
    Biostatistics, 18 (3), 586-587
    DOI 10.1093/biostatistics/kxx001, PubMed 28334081
  11. Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
    Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
    ESMO Open, 2 (2), e000158
    DOI 10.1136/esmoopen-2017-000158, PubMed 28761742
  12. Refinetti P, Arstad C, Thilly WG, Morgenthaler S, Ekstrøm PO (2017)
    Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis
    BMC Clin Pathol, 17, 6
    DOI 10.1186/s12907-017-0042-3, PubMed 28405177
  13. Rossi BM, Palmero EI, López-Kostner F, Sarroca C, Vaccaro CA, Spirandelli F, Ashton-Prolla P, Rodriguez Y, de Campos Reis Galvão H, Reis RM, Escremim de Paula A, Capochin Romagnolo LG, Alvarez K, Della Valle A, Neffa F, Kalfayan PG, Spirandelli E, Chialina S, Gutiérrez Angulo M, Castro-Mujica MDC, Sanchez de Monte J, Quispe R, da Silva SD, Rossi NT, Barletta-Carrillo C et al. (2017)
    A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
    BMC Cancer, 17 (1), 623
    DOI 10.1186/s12885-017-3599-4, PubMed 28874130
  14. Seppälä T, Pylvänäinen K, Evans DG, Järvinen H, Renkonen-Sinisalo L, Bernstein I, Holinski-Feder E, Sala P, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Genuardi M, Green K et al. (2017)
    Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report
    Hered Cancer Clin Pract, 15, 18
    DOI 10.1186/s13053-017-0078-5, PubMed 29046738
  15. Simovski B, Vodák D, Gundersen S, Domanska D, Azab A, Holden L, Holden M, Grytten I, Rand K, Drabløs F, Johansen M, Mora A, Lund-Andersen C, Fromm B, Eskeland R, Gabrielsen OS, Ferkingstad E, Nakken S, Bengtsen M, Nederbragt AJ, Thorarensen HS, Akse JA, Glad I, Hovig E, Sandve GK (2017)
    GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
    Gigascience, 6 (7), 1-12
    DOI 10.1093/gigascience/gix032, PubMed 28459977

Publications 2016

  1. Alver TN, Lavelle TJ, Longva AS, Øy GF, Hovig E, Bøe SL (2016)
    MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma
    Oncotarget, 7 (34), 55128-55140
    DOI 10.18632/oncotarget.10422, PubMed 27391157
  2. Arstad C, Refinetti P, Warren D, Giercksky KE, Ekstrøm PO (2016)
    Scanning the mitochondrial genome for mutations by cycling temperature capillary electrophoresis
    Mitochondrial DNA A DNA Mapp Seq Anal, 29 (1), 19-30
    DOI 10.1080/24701394.2016.1233532, PubMed 27728990
  3. Björklund AT, Clancy T, Goodridge JP, Béziat V, Schaffer M, Hovig E, Ljunggren HG, Ljungman PT, Malmberg KJ (2016)
    Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
    J Immunol, 196 (3), 1400-11
    DOI 10.4049/jimmunol.1501434, PubMed 26746188
  4. Børnich C, Grytten I, Hovig E, Paulsen J, Čech M, Sandve GK (2016)
    Galaxy Portal: interacting with the galaxy platform through mobile devices
    Bioinformatics, 32 (11), 1743-5
    DOI 10.1093/bioinformatics/btw042, PubMed 26819474
  5. Clancy T, Hovig E (2016)
    Profiling networks of distinct immune-cells in tumors
    BMC Bioinformatics, 17 (1), 263
    DOI 10.1186/s12859-016-1141-3, PubMed 27377892
  6. Di Stefano M, Paulsen J, Lien TG, Hovig E, Micheletti C (2016)
    Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization
    Sci Rep, 6, 35985
    DOI 10.1038/srep35985, PubMed 27786255
  7. Halvorsen AR, Silwal-Pandit L, Meza-Zepeda LA, Vodak D, Vu P, Sagerup C, Hovig E, Myklebost O, Børresen-Dale AL, Brustugun OT, Helland Å (2016)
    TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
    Front Genet, 7, 85
    DOI 10.3389/fgene.2016.00085, PubMed 27242894
  8. Haugvik SP, Vodák D, Haugom L, Hovig E, Gladhaug IP, Heim S, Micci F (2016)
    Transcriptomic Profiling of Tumor Aggressiveness in Sporadic Nonfunctioning Pancreatic Neuroendocrine Neoplasms
    Pancreas, 45 (8), 1196-203
    DOI 10.1097/MPA.0000000000000610, PubMed 26918873
  9. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    DOI 10.1002/ijc.30142, PubMed 27082076
  10. Jonsson M, Ragnum HB, Julin CH, Yeramian A, Clancy T, Frikstad KM, Seierstad T, Stokke T, Matias-Guiu X, Ree AH, Flatmark K, Lyng H (2016)
    Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
    Br J Cancer, 115 (8), 929-939
    DOI 10.1038/bjc.2016.278, PubMed 27599042
  11. Joshi S, Schjølberg AR, Ekstrøm PO, De Angelis PM, Zucknick M, Andersen SN, Clausen OP (2016)
    Tp53/p53 status in keratoacanthomas
    J Cutan Pathol, 43 (7), 571-8
    DOI 10.1111/cup.12713, PubMed 27020606
  12. Landfors M, Nakken S, Fusser M, Dahl JA, Klungland A, Fedorcsak P (2016)
    Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations
    Fertil Steril, 105 (5), 1170-1179.e5
    DOI 10.1016/j.fertnstert.2016.01.002, PubMed 26820768
  13. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Green K, Lalloo F, Sunde L, Mints M et al. (2016)
    Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
    Gut, 66 (9), 1657-1664
    DOI 10.1136/gutjnl-2016-311403, PubMed 27261338
  14. Späth F, Andersson U, Dahlin AM, Langseth H, Hovig E, Johannesen TB, Grankvist K, Björkblom B, Wibom C, Melin B (2016)
    Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study
    Tumour Biol, 37 (8), 11065-72
    DOI 10.1007/s13277-015-4742-y, PubMed 26906551

Publications 2015

  1. Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S et al. (2015)
    A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
    Nat Commun, 6, 10001
    DOI 10.1038/ncomms10001, PubMed 26647970
  2. Bengtsen M, Klepper K, Gundersen S, Cuervo I, Drabløs F, Hovig E, Sandve GK, Gabrielsen OS, Eskeland R (2015)
    c-Myb Binding Sites in Haematopoietic Chromatin Landscapes
    PLoS One, 10 (7), e0133280
    DOI 10.1371/journal.pone.0133280, PubMed 26208222
  3. Christiansen IK, Sandve GK, Schmitz M, Dürst M, Hovig E (2015)
    Transcriptionally active regions are the preferred targets for chromosomal HPV integration in cervical carcinogenesis
    PLoS One, 10 (3), e0119566
    DOI 10.1371/journal.pone.0119566, PubMed 25793388
  4. Ekstrøm PO, Nakken S, Johansen M, Hovig E (2015)
    Automated amplicon design suitable for analysis of DNA variants by melting techniques
    BMC Res Notes, 8, 667
    DOI 10.1186/s13104-015-1624-8, PubMed 26559640
  5. Friis-Ottessen M, Burum-Auensen E, Schjolberg AR, Ekstrom PO, Andersen SN, Clausen OP, De Angelis PM (2015)
    TP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitis
    Int. J. Mol. Med., 35 (1), 24-30
  6. Heramb C, Ekstrøm PO, Tharmaratnam K, Hovig E, Møller P, Mæhle L (2015)
    Ten modifiers of BRCA1 penetrance validated in a Norwegian series
    Hered Cancer Clin Pract, 13 (1), 14
    DOI 10.1186/s13053-015-0035-0, PubMed 26052370
  7. Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
    PLoS One, 10 (2), e0117261
    DOI 10.1371/journal.pone.0117261, PubMed 25706641
  8. Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
    Genom Data, 5, 176-83
    DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252
  9. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Green K, Lalloo F, Sunde L, Mints M, Bertario L et al. (2015)
    Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
    Gut, 66 (3), 464-472
    DOI 10.1136/gutjnl-2015-309675, PubMed 26657901
  10. Nygaard V, Rødland EA, Hovig E (2015)
    Methods that remove batch effects while retaining group differences may lead to exaggerated confidence in downstream analyses
    Biostatistics, 17 (1), 29-39
    DOI 10.1093/biostatistics/kxv027, PubMed 26272994
  11. Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A (2015)
    BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
    Blood Cancer J, 5, e299
    DOI 10.1038/bcj.2015.24, PubMed 25794135
  12. Rydbeck H, Sandve GK, Ferkingstad E, Simovski B, Rye M, Hovig E (2015)
    ClusTrack: feature extraction and similarity measures for clustering of genome-wide data sets
    PLoS One, 10 (4), e0123261
    DOI 10.1371/journal.pone.0123261, PubMed 25879845
  13. Wibom C, Späth F, Dahlin AM, Langseth H, Hovig E, Rajaraman P, Johannesen TB, Andersson U, Melin B (2015)
    Investigation of established genetic risk variants for glioma in prediagnostic samples from a population-based nested case-control study
    Cancer Epidemiol Biomarkers Prev, 24 (5), 810-6
    DOI 10.1158/1055-9965.EPI-14-1106, PubMed 25713050

Publications 2014

  1. Clancy T, Hovig E (2014)
    From proteomes to complexomes in the era of systems biology
    Proteomics, 14 (1), 24-41
    DOI 10.1002/pmic.201300230, PubMed 24243660
  2. Clancy T, Hovig E (2014)
    Differential Protein Network Analysis of the Immune Cell Lineage
    Biomed Res. Int., 2014, 363408
  3. Nygaard V, Prasmickaite L, Vasiliauskaite K, Clancy T, Hovig E (2014)
    Melanoma brain colonization involves the emergence of a brain-adaptive phenotype
    Oncoscience, 1 (1), 82-94
    DOI 10.18632/oncoscience.11, PubMed 25593989
  4. Paulsen J, Rødland EA, Holden L, Holden M, Hovig E (2014)
    A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions
    Nucleic Acids Res, 42 (18), e143
    DOI 10.1093/nar/gku738, PubMed 25114054
  5. Paulsen J, Sandve GK, Gundersen S, Lien TG, Trengereid K, Hovig E (2014)
    HiBrowse: multi-purpose statistical analysis of genome-wide chromatin 3D organization
    Bioinformatics, 30 (11), 1620-2
    DOI 10.1093/bioinformatics/btu082, PubMed 24511080

Publications 2013

  1. Bettum IJ, Vasiliauskaite K, Nygaard V, Clancy T, Pettersen SJ, Tenstad E, Mælandsmo GM, Prasmickaite L (2013)
    Metastasis-associated protein S100A4 induces a network of inflammatory cytokines that activate stromal cells to acquire pro-tumorigenic properties
    Cancer Lett, 344 (1), 28-39
    DOI 10.1016/j.canlet.2013.10.036, PubMed 24215866
  2. Bøe SL, Hovig E (2013)
    Light-induced mRNA transfection
    Methods Mol Biol, 969, 89-100
    DOI 10.1007/978-1-62703-260-5_6, PubMed 23296929
  3. Bøe SL, Jørgensen JA, Longva AS, Lavelle T, Sæbøe-Larssen S, Hovig E (2013)
    Light-controlled modulation of gene expression using polyamidoamine formulations
    Nucleic Acid Ther, 23 (2), 160-5
    DOI 10.1089/nat.2012.0413, PubMed 23530684
  4. Clancy T, Rødland EA, Nygard S, Hovig E (2013)
    Predicting physical interactions between protein complexes
    Mol Cell Proteomics, 12 (6), 1723-34
    DOI 10.1074/mcp.O112.019828, PubMed 23438732

Publications 2012

  1. Ekstrøm PO, Warren DJ, Thilly WG (2012)
    Separation principles of cycling temperature capillary electrophoresis
    Electrophoresis, 33 (7), 1162-8
    DOI 10.1002/elps.201100550, PubMed 22539319
  2. Liu F, Kuo WP, Jenssen TK, Hovig E (2012)
    Performance comparison of multiple microarray platforms for gene expression profiling
    Methods Mol Biol, 802, 141-55
    DOI 10.1007/978-1-61779-400-1_10, PubMed 22130879
  3. Nakken S, Johansen M, Fillebeen J, Berge OP, Kirkerød H, Jenssen TK, Hovig E (2012)
    CellLineMiner: a knowledge portal for human cell lines
    Bioinformation, 8 (22), 1119-22
    DOI 10.6026/97320630081119, PubMed 23251048
  4. Trachtenberg AJ, Robert JH, Abdalla AE, Fraser A, He SY, Lacy JN, Rivas-Morello C, Truong A, Hardiman G, Ohno-Machado L, Liu F, Hovig E, Kuo WP (2012)
    A primer on the current state of microarray technologies
    Methods Mol Biol, 802, 3-17
    DOI 10.1007/978-1-61779-400-1_1, PubMed 22130870

Publications 2011

  1. Bøe S, Prasmickaite L, Engesæter B, Hovig E (2011)
    Light-directed delivery of nucleic acids
    Methods Mol Biol, 764, 107-21
    DOI 10.1007/978-1-61779-188-8_7, PubMed 21748636
  2. Bøe SL, Longva AS, Hovig E (2011)
    A novel photosensitizer for light-controlled gene silencing
    Nucleic Acid Ther, 21 (5), 359-67
    DOI 10.1089/nat.2011.0309, PubMed 22004417
  3. Clancy T, Pedicini M, Castiglione F, Santoni D, Nygaard V, Lavelle TJ, Benson M, Hovig E (2011)
    Immunological network signatures of cancer progression and survival
    BMC Med Genomics, 4, 28
    DOI 10.1186/1755-8794-4-28, PubMed 21453479
  4. De Beule J, Hovig E, Benson M (2011)
    Introducing Dynamics into the Field of Biosemiotics A Formal Account with Examples from Language and Immunology
    Biosemiotics, 4 (1), 5-24
  5. Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
    CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
    Genes Immun, 12 (8), 653-62
    DOI 10.1038/gene.2011.43, PubMed 21716316

Publications 2010

  1. Bøe S, Saebøe-Larssen S, Hovig E (2010)
    Light-induced gene expression using messenger RNA molecules
    Oligonucleotides, 20 (1), 1-6
    DOI 10.1089/oli.2009.0209, PubMed 20038251
  2. Bøe SL, Longva AS, Hovig E (2010)
    Cyclodextrin-containing polymer delivery system for light-directed siRNA gene silencing
    Oligonucleotides, 20 (4), 175-82
    DOI 10.1089/oli.2010.0230, PubMed 20645877
  3. Cekaite L, Clancy T, Sioud M (2010)
    Increased miR-21 expression during human monocyte differentiation into DCs
    Front Biosci (Elite Ed), 2, 818-28
    DOI 10.2741/e143, PubMed 20515755
  4. Nakken S, Rødland EA, Hovig E (2010)
    Impact of DNA physical properties on local sequence bias of human mutation
    Hum Mutat, 31 (12), 1316-25
    DOI 10.1002/humu.21371, PubMed 20886615

Publications 2009

  1. Cekaite L, Hovig E, Sioud M (2009)
    Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
    Methods Mol Biol, 524, 273-85
    DOI 10.1007/978-1-59745-450-6_20, PubMed 19377952
  2. Nygaard V, Hovig E (2009)
    Methods for quantitation of gene expression
    Front Biosci (Landmark Ed), 14, 552-69
    DOI 10.2741/3262, PubMed 19273085

Publications 2008

  1. Boe S, Longva AS, Hovig E (2008)
    Evaluation of various polyethylenimine formulations for light-controlled gene silencing using small interfering RNA molecules
    Oligonucleotides, 18 (2), 123-32
    DOI 10.1089/oli.2008.0131, PubMed 18637730
  2. Boye K, Grotterød I, Aasheim HC, Hovig E, Maelandsmo GM (2008)
    Activation of NF-kappaB by extracellular S100A4: analysis of signal transduction mechanisms and identification of target genes
    Int J Cancer, 123 (6), 1301-10
    DOI 10.1002/ijc.23617, PubMed 18548584
  3. Nygaard V, Hovig E (2008)
    Cell sampling and global nucleic acid amplification
    SEB Exp Biol Ser, 61, 17-36
    PubMed 18709735
  4. Nygaard V, Liu F, Holden M, Kuo WP, Trimarchi J, Ohno-Machado L, Cepko CL, Frigessi A, Glad IK, Wiel MA, Hovig E, Lyng H (2008)
    Validation of oligoarrays for quantitative exploration of the transcriptome
    BMC Genomics, 9, 258
    DOI 10.1186/1471-2164-9-258, PubMed 18513391
  5. Tøstesen E (2008)
    A stitch in time: efficient computation of genomic DNA melting bubbles
    Algorithms Mol Biol, 3, 10
    DOI 10.1186/1748-7188-3-10, PubMed 18637171

Publications 2007

  1. Bøe S, Longva AS, Hovig E (2007)
    Photochemically induced gene silencing using small interfering RNA molecules in combination with lipid carriers
    Oligonucleotides, 17 (2), 166-73
    DOI 10.1089/oli.2007.0076, PubMed 17638521
  2. Cekaite L, Hovig E, Sioud M (2007)
    Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
    Methods Mol Biol, 360, 335-48
    DOI 10.1385/1-59745-165-7:335, PubMed 17172738
  3. Cekaite L, Peng Q, Reiner A, Shahzidi S, Tveito S, Furre IE, Hovig E (2007)
    Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
    BMC Genomics, 8, 273
    DOI 10.1186/1471-2164-8-273, PubMed 17692132
  4. Liu F, Jenssen TK, Trimarchi J, Punzo C, Cepko CL, Ohno-Machado L, Hovig E, Kuo WP (2007)
    Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates
    BMC Genomics, 8, 153
    DOI 10.1186/1471-2164-8-153, PubMed 17555589
  5. Liu F, Tøstesen E, Sundet JK, Jenssen TK, Bock C, Jerstad GI, Thilly WG, Hovig E (2007)
    The human genomic melting map
    PLoS Comput Biol, 3 (5), e93
    DOI 10.1371/journal.pcbi.0030093, PubMed 17511513
  6. Møller P, Hagen AI, Apold J, Maehle L, Clark N, Fiane B, Løvslett K, Hovig E, Vabø A (2007)
    Genetic epidemiology of BRCA mutations--family history detects less than 50% of the mutation carriers
    Eur J Cancer, 43 (11), 1713-7
    DOI 10.1016/j.ejca.2007.04.023, PubMed 17574839

Publications 2006

  1. Berner JM, Muller CR, Holden M, Wang J, Hovig E, Myklebost O (2006)
    Sampling effects on gene expression data from a human tumour xenograft
    Scand. J. Lab. Anim. Sci., 33 (1), 17-30
  2. Bøe S, Hovig E (2006)
    Photochemically induced gene silencing using PNA-peptide conjugates
    Oligonucleotides, 16 (2), 145-57
    DOI 10.1089/oli.2006.16.145, PubMed 16764538
  3. Cekaite L, Furset G, Hovig E, Sioud M (2006)
    Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
    J Mol Biol, 365 (1), 90-108
    DOI 10.1016/j.jmb.2006.09.034, PubMed 17054988
  4. Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF, Freeman MW, Seed B et al. (2006)
    A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies
    Nat Biotechnol, 24 (7), 832-40
    DOI 10.1038/nbt1217, PubMed 16823376
  5. Nygaard V, Hovig E (2006)
    Options available for profiling small samples: a review of sample amplification technology when combined with microarray profiling
    Nucleic Acids Res, 34 (3), 996-1014
    DOI 10.1093/nar/gkj499, PubMed 16473852

Publications 2005

  1. Nygaard V, Holden M, Løland A, Langaas M, Myklebost O, Hovig E (2005)
    Limitations of mRNA amplification from small-size cell samples
    BMC Genomics, 6, 147
    DOI 10.1186/1471-2164-6-147, PubMed 16253144
  2. Tøstesen E (2005)
    Partly melted DNA conformations obtained with a probability peak finding method
    Phys Rev E Stat Nonlin Soft Matter Phys, 71 (6 Pt 1), 061922
    DOI 10.1103/PhysRevE.71.061922, PubMed 16089780
  3. Tøstesen E, Jerstad GI, Hovig E (2005)
    Stitchprofiles.uio.no: analysis of partly melted DNA conformations using stitch profiles
    Nucleic Acids Res, 33 (Web Server issue), W573-6
    DOI 10.1093/nar/gki424, PubMed 15980539

Publications 2004

  1. Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
    Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
    Proteomics, 4 (9), 2572-82
    DOI 10.1002/pmic.200300768, PubMed 15352232
  2. Cekaite L, Hovig E, Hauge HH (2004)
    Double-sided silicon strip detectors: new applications within genomics and proteomics
    Nucl. Instrum. Methods Phys. Res. Sect. A-Accel. Spectrom. Dect. Assoc. Equip., 527 (1-2), 68-72
  3. Liu F, Jenssen TK, Nygaard V, Sack J, Hovig E (2004)
    FigSearch: Using maximum entropy classifier to categorize biological figures
    2004 IEEE COMPUTATIONAL SYSTEMS BIOINFORMATICS CONFERENCE, PROCEEDINGS, 476-477
  4. Liu F, Jenssen TK, Nygaard V, Sack J, Hovig E (2004)
    FigSearch: a figure legend indexing and classification system
    Bioinformatics, 20 (16), 2880-2
    DOI 10.1093/bioinformatics/bth316, PubMed 15145804
  5. Wang X, Wang M, Amarzguioui M, Liu F, Fodstad Ø, Prydz H (2004)
    Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
    Int J Cancer, 112 (6), 994-1002
    DOI 10.1002/ijc.20527, PubMed 15386437

Publications 2003

  1. Nygaard V, Løland A, Holden M, Langaas M, Rue H, Liu F, Myklebost O, Fodstad Ø, Hovig E, Smith-Sørensen B (2003)
    Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
    BMC Genomics, 4 (1), 11
    DOI 10.1186/1471-2164-4-11, PubMed 12659661
  2. Tøstesen E, Liu F, Jenssen TK, Hovig E (2003)
    Speed-up of DNA melting algorithm with complete nearest neighbor properties
    Biopolymers, 70 (3), 364-76
    DOI 10.1002/bip.10495, PubMed 14579309

Publications 2002

  1. Jenssen TK, Hovig E (2002)
    The semantic web and biology
    Drug Discov Today, 7 (19), 992
    DOI 10.1016/s1359-6446(02)02458-3, PubMed 12546914
  2. Smith-Sørensen B, Lind GE, Skotheim RI, Fosså SD, Fodstad Ø, Stenwig AE, Jakobsen KS, Lothe RA (2002)
    Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancer
    Oncogene, 21 (57), 8878-84
    DOI 10.1038/sj.onc.1205978, PubMed 12483540

Publications 2001

  1. Hovig E, Maelandsmo G, Mellingsaeter T, Fodstad O, Mielewczyk SS, Wolfe J, Goodchild J (2001)
    Optimization of hammerhead ribozymes for the cleavage of S100A4 (CAPL) mRNA
    Antisense Nucleic Acid Drug Dev, 11 (2), 67-75
    DOI 10.1089/108729001750171272, PubMed 11334142
  2. Hovig E, Rye PD, Warren DJ, Nustad K (2001)
    CA 125: the end of the beginning
    Tumour Biol, 22 (6), 345-7
    DOI 10.1159/000050637, PubMed 11786728

Publications 2000

  1. Komorowski J, Hvidsten TR, Jenssen TK, Tjeldvoll D, Hovig E, Sandvik AK, Laegreid A (2000)
    Towards Knowledge Discovery from cDNA Microarray Gene Expression Data
    Lect. Notes Comput. Sci., 1910, 470-475

Publications 1999

  1. Lonning PE, Johnsen H, Geisler S, Aas T, Smith-Sorensen B, Akslen LA, Borresen-Dale AL (1999)
    TP53 as a predictor of response to chemotherapy in breast cancer
    ESO SCI UPDATES, 4, 73-88

Publications 1996

  1. Hovig E, Fodstad O (1996)
    [Prostate-specific membrane antigen]
    Tidsskr Nor Laegeforen, 116 (3), 411-2
    PubMed 8638273

Publications 1992

  1. Hovig E, Smith-Sørensen B, Uitterlinden AG, Børresen AL (1992)
    Detection of DNA variation in cancer
    Pharmacogenetics, 2 (6), 317-28
    DOI 10.1097/00008571-199212000-00011, PubMed 1306133

Publications 1991

  1. Hovig, Eivind, Smith-Sørensen B, Brøgger A, Børrensen AL (1991)
    Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
    Mutat Res, 263 (1), 61
    DOI 10.1016/0165-7992(91)90036-4, PubMed 2034242

Publications 1990

  1. BORRESEN AL, HOVIG E, SMITHSORENSEN B, VRIELING H, APOLD J, BROGGER A (1990)
    SCREENING FOR BASE MUTATIONS IN THE PAH AND HPRT LOCI USING THE POLYMERASE CHAIN-REACTION (PCR) IN COMBINATION WITH DENATURING GRADIENT GEL-ELECTROPHORESIS (DGGE)
    Prog.Clin.Biol.Res., 340, 389-398

Publications 1989

  1. OLSNES S, STENMARK H, MCGILL S, HOVIG E, COLLIER RJ, SANDVIG K (1989)
    FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
    J. Biol. Chem., 264 (22), 12749-12751

Publications 1987

  1. Hovig E, Winberg JO, Fodstad O, Brøgger A, Gedde-Dahl T (1987)
    Chromosome 13 instability and esterase D expression in an osteosarcoma cell line
    Cancer Genet Cytogenet, 24 (2), 327-34
    DOI 10.1016/0165-4608(87)90115-4, PubMed 2878716
 
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