Publications published since 1987 from OUS - Computational Cancer Genomics and Melanoma Systems Biology (Hovig)

366 publications found

Publications 2024

  1. Cavanaugh D, Urbanucci A, Mohamed NE, Tewari AK, Figueiro M, Kyprianou N (2024)
    Link between circadian rhythm and benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS)
    Prostate, 84 (5), 417-425
    DOI 10.1002/pros.24656, PubMed 38193363
  2. Edsjö A, Russnes HG, Lehtiö J, Tamborero D, Hovig E, Stenzinger A, Rosenquist R, PCM4EU consortium (2024)
    High-throughput molecular assays for inclusion in personalised oncology trials - State-of-the-art and beyond
    J Intern Med, 295 (6), 785-803
    DOI 10.1111/joim.13785, PubMed 38698538
  3. Esperon P, Neffa F, Pavicic W, Spirandelli F, Alvarez K, Mullins MJ, Rossi BM, Góngora E Silva RF, Vaccaro C, Lopéz-Köstner F, Rugeles J, Valle AD, Dominguez-Valentin M (2024)
    A comprehensive characterization of the spectrum of MUTYH germline pathogenic variants in Latin America
    Fam Cancer (in press)
    DOI 10.1007/s10689-024-00382-3, PubMed 38687439
  4. Kandathil SA, Akhondi A, Kadletz-Wanke L, Heiduschka G, Engedal N, Brkic FF (2024)
    The dual role of autophagy in HPV-positive head and neck squamous cell carcinoma: a systematic review
    J Cancer Res Clin Oncol, 150 (2), 56
    DOI 10.1007/s00432-023-05514-3, PubMed 38291202
  5. Kotsopoulos J, Gronwald J, Huzarski T, Møller P, Pal T, McCuaig JM, Singer CF, Karlan BY, Aeilts A, Eng C, Eisen A, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Neuhausen SL, Zakalik D, Cybulski C, Metcalfe K, Olopade OI, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2024)
    Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations
    JAMA Oncol, 10 (4), 484-492
    DOI 10.1001/jamaoncol.2023.6937, PubMed 38421677
  6. Lubinski J, Kotsopoulos J, Moller P, Pal T, Eisen A, Peck L, Karlan BY, Aeilts A, Eng C, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Ramon Y Cajal T, Singer CF, Neuhausen SL, Zakalik D, Cybulski C, Gronwald J, Huzarski T, Stempa K, Dungan J, Cullinane C, Olopade OI et al. (2024)
    MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations
    JAMA Oncol, 10 (4), 493-499
    DOI 10.1001/jamaoncol.2023.6944, PubMed 38421676
  7. Møller P, Haupt S, Ahadova A, Kloor M, Sampson JR, Sunde L, Seppälä T, Burn J, Bernstein I, Capella G, Evans DG, Lindblom A, Winship I, Macrae F, Katz L, Laish I, Vainer E, Monahan K, Half E, Horisberger K, da Silva LA, Heuveline V, Therkildsen C, Lautrup C, Klarskov LL et al. (2024)
    Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated "Big Bang" pathway to CRC in three of the four Lynch syndromes
    Hered Cancer Clin Pract, 22 (1), 6
    DOI 10.1186/s13053-024-00279-3, PubMed 38741120
  8. Nikolski M, Hovig E, Al-Shahrour F, Blomberg N, Scollen S, Valencia A, Saunders G (2024)
    Roadmap for a European cancer data management and precision medicine infrastructure
    Nat Cancer, 5 (3), 367-372
    DOI 10.1038/s43018-023-00717-6, PubMed 38321342
  9. Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Chèneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A (2024)
    JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
    Nucleic Acids Res, 52 (D1), D174-D182
    DOI 10.1093/nar/gkad1059, PubMed 37962376
  10. van der Werf-'t Lam AS, Rodriguez-Girondo M, Villasmil M, Tops CM, van Hest L, Gille HJP, Duijkers FAM, Wagner A, Eikenboom E, Letteboer TGW, de Jong MM, Bajwa-Ten Broeke SW, Bleeker F, Gomez Garcia EB, Dominguez-Valentin M, Møller P, Suerink M, Nielsen M (2024)
    Delineating genotype and parent-of-origin effect on the phenotype in MSH6-associated Lynch syndrome
    Genes Chromosomes Cancer, 63 (5), e23237
    DOI 10.1002/gcc.23237, PubMed 38722212

Publications 2023

  1. Akdeniz BC, Mattingsdal M, Dominguez-Valentin M, Frei O, Shadrin A, Puustusmaa M, Saar R, Sõber S, Møller P, Andreassen OA, Padrik P, Hovig E (2023)
    A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
    Cancers (Basel), 15 (16)
    DOI 10.3390/cancers15164124, PubMed 37627152
  2. Billingham L, Brown L, Framke T, Greystoke A, Hovig E, Mathur S, Page P, Pean E, Barjesteh van Waalwijk van Doorn-Khosrovani S, Vonk R, Wissink S, Zander H, Plummer R (2023)
    Histology independent drug development - Is this the future for cancer drugs?
    Cancer Treat Rev, 123, 102674
    DOI 10.1016/j.ctrv.2023.102674, PubMed 38176220
  3. Dominguez-Valentin M, Haupt S, Seppälä TT, Sampson JR, Sunde L, Bernstein I, Jenkins MA, Engel C, Aretz S, Nielsen M, Capella G, Balaguer F, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Della Valle A et al. (2023)
    Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
    EClinicalMedicine, 58, 101909
    DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409
  4. Ellingsen EB, O'Day S, Mezheyeuski A, Gromadka A, Clancy T, Kristedja TS, Milhem M, Zakharia Y (2023)
    Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
    Clin Cancer Res, 29 (16), 3026-3036
    DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632
  5. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
    screenwerk: a modular tool for the design and analysis of drug combination screens
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac840, PubMed 36573326
  6. Hodan R, Rodgers-Fouche L, Chittenden A, Dominguez-Valentin M, Ferriss J, Gima L, Hamnvik OR, Idos GE, Kline K, Koeller DR, Long JM, McKenna D, Muller C, Thoman M, Wintner A, Bedrick BS, Collaborative Group of the Americas on Inherited Gastrointestinal Cancer (2023)
    Cancer surveillance for transgender and gender diverse patients with Lynch syndrome: a practice resource of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    Fam Cancer, 22 (4), 437-448
    DOI 10.1007/s10689-023-00341-4, PubMed 37341816
  7. Ibrahim EIK, Ellingsen EB, Mangsbo SM, Friberg LE (2023)
    Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model
    Int Immunopharmacol, 126, 111225
    DOI 10.1016/j.intimp.2023.111225, PubMed 37988911
  8. Kalyanasundaram S, Lefol Y, Gundersen S, Rognes T, Alsøe L, Nilsen HL, Hovig E, Sandve GK, Domanska D (2023)
    hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
    PLoS One, 18 (7), e0286330
    DOI 10.1371/journal.pone.0286330, PubMed 37467208
  9. Mraz KA, Hodan R, Rodgers-Fouche L, Arora S, Balaguer F, Guillem JG, Jeter JM, Kanth P, Li D, Liska D, Melson J, Perez K, Ricker C, Shirts BH, Vilar E, Katona BW, Dominguez-Valentin M (2023)
    Current chemoprevention approaches in Lynch syndrome and Familial adenomatous polyposis: a global clinical practice survey
    Front Oncol, 13, 1141810
    DOI 10.3389/fonc.2023.1141810, PubMed 37293588
  10. Møller P, Seppälä TT, Ahadova A, Crosbie EJ, Holinski-Feder E, Scott R, Haupt S, Möslein G, Winship I, Broeke SWB, Kohut KE, Ryan N, Bauerfeind P, Thomas LE, Evans DG, Aretz S, Sijmons RH, Half E, Heinimann K, Horisberger K, Monahan K, Engel C, Cavestro GM, Fruscio R, Abu-Freha N et al. (2023)
    Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
    Hered Cancer Clin Pract, 21 (1), 19
    DOI 10.1186/s13053-023-00263-3, PubMed 37821984
  11. Nakken S, Gundersen S, Bernal FLM, Polychronopoulos D, Hovig E, Wesche J (2023)
    Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR
    Int J Cancer, 153 (10), 1819-1828
    DOI 10.1002/ijc.34666, PubMed 37551617
  12. Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
    Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
    Mol Oncol, 17 (11), 2432-2450
    DOI 10.1002/1878-0261.13514, PubMed 37622176
  13. Parry MA, Grist E, Mendes L, Dutey-Magni P, Sachdeva A, Brawley C, Murphy L, Proudfoot J, Lall S, Liu Y, Friedrich S, Ismail M, Hoyle A, Ali A, Haran A, Wingate A, Zakka L, Wetterskog D, Amos CL, Atako NB, Wang V, Rush HL, Jones RJ, Leung H, Cross WR et al. (2023)
    Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial
    Res Sq
    DOI 10.21203/, PubMed 36798177
  14. Połeć A, Ekstrøm PO, Fougner C, Sørlie T, Norum JH (2023)
    Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
    BMC Res Notes, 16 (1), 167
    DOI 10.1186/s13104-023-06437-5, PubMed 37568187
  15. Rodgers-Fouche L, Arora S, Ricker C, Li D, Farooqi M, Balaguer F, Dominguez-Valentin M, Guillem JG, Kanth P, Liska D, Melson J, Mraz KA, Shirts BH, Vilar E, Katona BW, Hodan R (2023)
    Exploring Stakeholders' Perspectives on Implementing Universal Germline Testing for Colorectal Cancer: Findings From a Clinical Practice Survey
    JCO Precis Oncol, 7, e2300440
    DOI 10.1200/PO.23.00440, PubMed 37897815
  16. Rodríguez-Varela R, Moore KHS, Ebenesersdóttir SS, Kilinc GM, Kjellström A, Papmehl-Dufay L, Alfsdotter C, Berglund B, Alrawi L, Kashuba N, Sobrado V, Lagerholm VK, Gilbert E, Cavalleri GL, Hovig E, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Munters AR, Bernhardsson C, Skar B, Christophersen A, Turner-Walker G et al. (2023)
    The genetic history of Scandinavia from the Roman Iron Age to the present
    Cell, 186 (1), 32-46.e19
    DOI 10.1016/j.cell.2022.11.024, PubMed 36608656
  17. Severson TM, Zhu Y, Prekovic S, Schuurman K, Nguyen HM, Brown LG, Hakkola S, Kim Y, Kneppers J, Linder S, Stelloo S, Lieftink C, van der Heijden M, Nykter M, van der Noort V, Sanders J, Morris B, Jenster G, van Leenders GJ, Pomerantz M, Freedman ML, Beijersbergen RL, Urbanucci A, Wessels L, Corey E et al. (2023)
    Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients
    DOI 10.1101/2023.02.24.23286403, PubMed 36865297
  18. Tamargo-Gómez I, Martínez-García GG, Suárez MF, Mayoral P, Bretones G, Astudillo A, Prieto-Lloret J, Sveen C, Fueyo A, Engedal N, López-Otín C, Mariño G (2023)
    Analysis of ATG4C function in vivo
    Autophagy, 19 (11), 2912-2933
    DOI 10.1080/15548627.2023.2234799, PubMed 37459465

Publications 2022

  1. Ahadova A, Witt J, Haupt S, Gallon R, Hüneburg R, Nattermann J, Ten Broeke S, Bohaumilitzky L, Hernandez-Sanchez A, Santibanez-Koref M, Jackson MS, Ahtiainen M, Pylvänäinen K, Andini K, Grolmusz VK, Möslein G, Dominguez-Valentin M, Møller P, Fürst D, Sijmons R, Borthwick GM, Burn J, Mecklin JP, Heuveline V, von Knebel Doeberitz M et al. (2022)
    Is HLA type a possible cancer risk modifier in Lynch syndrome?
    Int J Cancer, 152 (10), 2024-2031
    DOI 10.1002/ijc.34312, PubMed 36214792
  2. Alver TN, Heintz KM, Hovig E, Bøe SL (2022)
    Cooperative induction of receptor tyrosine kinases contributes to adaptive MAPK drug resistance in melanoma through the PI3K pathway
    Cancer Rep (Hoboken), 6 (2), e1736
    DOI 10.1002/cnr2.1736, PubMed 36251678
  3. Cao S, Wang JR, Ji S, Yang P, Dai Y, Guo S, Montierth MD, Shen JP, Zhao X, Chen J, Lee JJ, Guerrero PA, Spetsieris N, Engedal N, Taavitsainen S, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA, Efstathiou E, Lim B, Viale A, Zhang J et al. (2022)
    Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression
    Nat Biotechnol, 40 (11), 1624-1633
    DOI 10.1038/s41587-022-01342-x, PubMed 35697807
  4. Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A et al. (2022)
    Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
    Clin Gastroenterol Hepatol, 21 (3), 581-603.e33
    DOI 10.1016/j.cgh.2022.12.006, PubMed 36549470
  5. Dominguez-Valentin M, Sampson JR, Seppälä TT, Møller P (2022)
    Response to Chambuso et al
    Genet Med, 24 (5), 1151
    DOI 10.1016/j.gim.2022.01.005, PubMed 35216900
  6. Ellingsen EB, Bounova G, Kerzeli I, Anzar I, Simnica D, Aamdal E, Guren T, Clancy T, Mezheyeuski A, Inderberg EM, Mangsbo SM, Binder M, Hovig E, Gaudernack G (2022)
    Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
    J Transl Med, 20 (1), 419
    DOI 10.1186/s12967-022-03624-z, PubMed 36089578
  7. Ellingsen EB, Aamdal E, Guren T, Lilleby W, Brunsvig PF, Mangsbo SM, Aamdal S, Hovig E, Mensali N, Gaudernack G, Inderberg EM (2022)
    Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials
    J Immunother Cancer, 10 (5)
    DOI 10.1136/jitc-2021-004345, PubMed 35613827
  8. Engedal N, Proikas-Cezanne T, Albertini MC, Žerovnik E, Lane JD (2022)
    Transautophagy: Research and Translation of Autophagy Knowledge 2020
    Oxid Med Cell Longev, 2022, 9792132
    DOI 10.1155/2022/9792132, PubMed 35340207
  9. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
  10. Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
    Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
    Br J Cancer, 127 (11), 1939-1953
    DOI 10.1038/s41416-022-01973-6, PubMed 36097178
  11. Flobak Å, Skånland SS, Hovig E, Taskén K, Russnes HG (2022)
    Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
    Trends Pharmacol Sci, 43 (11), 973-985
    DOI 10.1016/, PubMed 36163057
  12. Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
    MirGeneDB 2.1: toward a complete sampling of all major animal phyla
    Nucleic Acids Res, 50 (D1), D204-D210
    DOI 10.1093/nar/gkab1101, PubMed 34850127
  13. Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
    Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
    Front Oncol, 12, 1040730
    DOI 10.3389/fonc.2022.1040730, PubMed 36523963
  14. Gopalakrishnan S, Ebenesersdóttir SS, Lundstrøm IKC, Turner-Walker G, Moore KHS, Luisi P, Margaryan A, Martin MD, Ellegaard MR, Magnússon ÓÞ, Sigurðsson Á, Snorradóttir S, Magnúsdóttir DN, Laffoon JE, van Dorp L, Liu X, Moltke I, Ávila-Arcos MC, Schraiber JG, Rasmussen S, Juan D, Gelabert P, de-Dios T, Fotakis AK, Iraeta-Orbegozo M et al. (2022)
    The population genomic legacy of the second plague pandemic
    Curr Biol, 32 (21), 4743-4751.e6
    DOI 10.1016/j.cub.2022.09.023, PubMed 36182700
  15. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 225
    DOI 10.1186/s12967-022-03432-5, PubMed 35568909
  16. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 317
    DOI 10.1186/s12967-022-03518-0, PubMed 35841045
  17. Hodan R, Rodgers-Fouche L, Arora S, Dominguez-Valentin M, Kanth P, Katona BW, Mraz KA, Roberts ME, Vilar E, Soto-Azghani CM, Brand RE, Esplin ED, Perez K (2022)
    Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    J Genet Couns, 31 (4), 949-955
    DOI 10.1002/jgc4.1567, PubMed 35218578
  18. Høye E, Fromm B, Böttger PHM, Domanska D, Torgunrud A, Lund-Andersen C, Abrahamsen TW, Fretland ÅA, Dagenborg VJ, Lorenz S, Edwin B, Hovig E, Flatmark K (2022)
    A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
    NAR Cancer, 4 (1), zcab051
    DOI 10.1093/narcan/zcab051, PubMed 35047825
  19. Li H, Engel C, Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2022)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (10), 2208
    DOI 10.1016/j.gim.2022.08.005, PubMed 36205748
  20. Metcalfe KA, Gronwald J, Tung NM, McCuaig JM, Eisen A, Elser C, Foulkes WD, Neuhausen SL, Senter L, Moller P, Bordeleau L, Fruscio R, Velsher L, Zakalik D, Olopade OI, Eng C, Pal T, Cullinane CA, Couch FJ, Kotsopoulos J, Sun P, Lubinski J, Narod SA (2022)
    The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
    Cancer, 129 (6), 901-907
    DOI 10.1002/cncr.34615, PubMed 36571512
  21. Misund K, Hofste Op Bruinink D, Coward E, Hoogenboezem RM, Rustad EH, Sanders MA, Rye M, Sponaas AM, van der Holt B, Zweegman S, Hovig E, Meza-Zepeda LA, Sundan A, Myklebost O, Sonneveld P, Waage A (2022)
    Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
    Leukemia, 36 (7), 1887-1897
    DOI 10.1038/s41375-022-01597-y, PubMed 35643867
  22. Møller P (2022)
    The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
    Hered Cancer Clin Pract, 20 (1), 37
    DOI 10.1186/s13053-022-00243-z, PubMed 36411472
  23. Møller P, Evans DG (2022)
    Inherited Cancer Genetic Epidemiology to Improve Precision Medicine
    J Clin Med, 11 (3)
    DOI 10.3390/jcm11030879, PubMed 35160330
  24. Møller P, Seppälä T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L, Bernstein I, Engel C, Aretz S, Nielsen M, Capella G, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Valle AD, Heinimann K et al. (2022)
    Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
    Hered Cancer Clin Pract, 20 (1), 36
    DOI 10.1186/s13053-022-00241-1, PubMed 36182917
  25. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
    The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
    Nat Commun, 13 (1), 6283
    DOI 10.1038/s41467-022-33933-2, PubMed 36270994
  26. Nyakas M, Fleten KG, Haugen MH, Engedal N, Sveen C, Farstad IN, Flørenes VA, Prasmickaite L, Mælandsmo GM, Seip K (2022)
    AXL inhibition improves BRAF-targeted treatment in melanoma
    Sci Rep, 12 (1), 5076
    DOI 10.1038/s41598-022-09078-z, PubMed 35332208
  27. Taskén K, Russnes HEG, Aas E, Bjørge L, Blix ES, CONNECT Public–Private Partnership Consortium, Enerly E, Fagereng GL, Flobak Å, Gilje B, Gjertsen BT, Guren TK, Heix J, Hovig E, Hovland R, InPreD-Norway and National Molecular Tumor Board Consortium, IMPRESS-Norway Consortium, Lønning PE, Meza-Zepeda LA, Mæhle PM, Nilsen HL, Thoresen SØ, Widerberg K, Smeland S, Helland Å (2022)
    A national precision cancer medicine implementation initiative for Norway
    Nat Med, 28 (5), 885-887
    DOI 10.1038/s41591-022-01777-4, PubMed 35513529
  28. Thomassen M, Mesman RLS, Hansen TVO, Menendez M, Rossing M, Esteban-Sánchez A, Tudini E, Törngren T, Parsons MT, Pedersen IS, Teo SH, Kruse TA, Møller P, Borg Å, Jensen UB, Christensen LL, Singer CF, Muhr D, Santamarina M, Brandao R, Andresen BS, Feng BJ, Canson D, Richardson ME, Karam R et al. (2022)
    Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach
    Hum Mutat, 43 (12), 1921-1944
    DOI 10.1002/humu.24449, PubMed 35979650
  29. Vaccaro CA, Soarez J, Dominguez-Valentin M, Pavicic WH (2022)
    Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer
    Front Oncol, 12, 1104671
    DOI 10.3389/fonc.2022.1104671, PubMed 36601476
  30. Venizelos A, Engebrethsen C, Deng W, Geisler J, Geisler S, Iversen GT, Aas T, Aase HS, Seyedzadeh M, Steinskog ES, Myklebost O, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Lønning PE, Knappskog S, Eikesdal HP (2022)
    Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
    Genome Med, 14 (1), 86
    DOI 10.1186/s13073-022-01090-2, PubMed 35948919
  31. Xia YY, Gronwald J, Karlan B, Lubinski J, McCuaig JM, Brooks J, Moller P, Eisen A, Sun S, Senter L, Bordeleau L, Neuhausen SL, Singer CF, Tung N, Foulkes WD, Sun P, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2022)
    Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 164 (3), 514-521
    DOI 10.1016/j.ygyno.2022.01.014, PubMed 35063280
  32. Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
    Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
    Cancers (Basel), 14 (22)
    DOI 10.3390/cancers14225603, PubMed 36428697

Publications 2021

  1. Cangiano M, Grudniewska M, Salji MJ, Nykter M, Jenster G, Urbanucci A, Granchi Z, Janssen B, Hamilton G, Leung HY, Beumer IJ (2021)
    Gene Regulation Network Analysis on Human Prostate Orthografts Highlights a Potential Role for the JMJD6 Regulon in Clinical Prostate Cancer
    Cancers (Basel), 13 (9)
    DOI 10.3390/cancers13092094, PubMed 33925994
  2. Christensen SB, Simonsen HT, Engedal N, Nissen P, Møller JV, Denmeade SR, Isaacs JT (2021)
    From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
    Prog Chem Org Nat Prod, 115, 59-114
    DOI 10.1007/978-3-030-64853-4_2, PubMed 33797641
  3. Dominguez-Valentin M, Plazzer JP, Sampson JR, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Macrae F, Winship IM, Thomas H, Evans DG, Burn J, Greenblatt M, de Vos Tot Nederveen Cappel WH, Sijmons RH, Nielsen M, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Lindblom A, Valle AD et al. (2021)
    No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
    J Clin Med, 10 (13)
    DOI 10.3390/jcm10132856, PubMed 34203177
  4. Ellingsen EB, Mangsbo SM, Hovig E, Gaudernack G (2021)
    Telomerase as a Target for Therapeutic Cancer Vaccines and Considerations for Optimizing Their Clinical Potential
    Front Immunol, 12, 682492
    DOI 10.3389/fimmu.2021.682492, PubMed 34290704
  5. Gundersen S, Boddu S, Capella-Gutierrez S, Drabløs F, Fernández JM, Kompova R, Taylor K, Titov D, Zerbino D, Hovig E (2021)
    Recommendations for the FAIRification of genomic track metadata
    F1000Res, 10
    DOI 10.12688/f1000research.28449.1, PubMed 34249331
  6. Haakensen VD, Nowak AK, Ellingsen EB, Farooqi SJ, Bjaanæs MM, Horndalsveen H, Mcculloch T, Grundberg O, Cedres SM, Helland Å (2021)
    NIPU: a randomised, open-label, phase II study evaluating nivolumab and ipilimumab combined with UV1 vaccination as second line treatment in patients with malignant mesothelioma
    J Transl Med, 19 (1), 232
    DOI 10.1186/s12967-021-02905-3, PubMed 34059094
  7. Kanduri C, Sandve GK, Hovig E, De S, Layer RM (2021)
    Editorial: Genomic Colocalization and Enrichment Analyses
    Front Genet, 11, 617876
    DOI 10.3389/fgene.2020.617876, PubMed 33574832
  8. Kim SJ, Lubinski J, Huzarski T, Møller P, Armel S, Karlan BY, Senter L, Eisen A, Foulkes WD, Singer CF, Tung N, Bordeleau L, Neuhausen SL, Olopade OI, Eng C, Weitzel JN, Fruscio R, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2021)
    Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers
    Cancer Epidemiol Biomarkers Prev, 30 (11), 2038-2043
    DOI 10.1158/1055-9965.EPI-21-0296, PubMed 34426412
  9. Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
    Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
    Autophagy, 17 (1), 1-382
    DOI 10.1080/15548627.2020.1797280, PubMed 33634751
  10. Kukkonen K, Taavitsainen S, Huhtala L, Uusi-Makela J, Granberg KJ, Nykter M, Urbanucci A (2021)
    Chromatin and Epigenetic Dysregulation of Prostate Cancer Development, Progression, and Therapeutic Response
    Cancers (Basel), 13 (13)
    DOI 10.3390/cancers13133325, PubMed 34283056
  11. Kværner AS, Birkeland E, Bucher-Johannessen C, Vinberg E, Nordby JI, Kangas H, Bemanian V, Ellonen P, Botteri E, Natvig E, Rognes T, Hovig E, Lyle R, Ambur OH, de Vos WM, Bultman S, Hjartåker A, Landberg R, Song M, Blix HS, Ursin G, Randel KR, de Lange T, Hoff G, Holme Ø et al. (2021)
    The CRCbiome study: a large prospective cohort study examining the role of lifestyle and the gut microbiome in colorectal cancer screening participants
    BMC Cancer, 21 (1), 930
    DOI 10.1186/s12885-021-08640-8, PubMed 34407780
  12. Lesueur F, Easton DF, Renault AL, Tavtigian SV, Bernstein JL, Kote-Jarai Z, Eeles RA, Plaseska-Karanfia D, Feliubadaló L, Spanish ATM working group, Arun B, Herold N, Versmold B, Schmutzler RK, GC-HBOC, Nguyen-Dumont T, Southey MC, Dorling L, Dunning AM, Ghiorzo P, Dalmasso BS, Cavaciuti E, Le Gal D, Roberts NJ, Dominguez-Valentin M et al. (2021)
    First international workshop of the ATM and cancer risk group (4-5 December 2019)
    Fam Cancer, 21 (2), 211-227
    DOI 10.1007/s10689-021-00248-y, PubMed 34125377
  13. Li H, Engel C, de la Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2021)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (1), 119-129
    DOI 10.1016/j.gim.2021.08.016, PubMed 34906479
  14. Mattingsdal M, Ebenesersdóttir SS, Moore KHS, Andreassen OA, Hansen TF, Werge T, Kockum I, Olsson T, Alfredsson L, Helgason A, Stefánsson K, Hovig E (2021)
    The genetic structure of Norway
    Eur J Hum Genet, 29 (11), 1710-1718
    DOI 10.1038/s41431-021-00899-6, PubMed 34002043
  15. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2021)
    Correction to: Letter to the Editor-Recent advances in Lynch syndrome
    Fam Cancer, 20 (2), 119
    DOI 10.1007/s10689-021-00246-0, PubMed 33792829
  16. Møller P, Sampson JR, Dominguez-Valentin M, Seppälä TT (2021)
    Towards evidence-based personalised precision medicine for Lynch syndrome
    Lancet Oncol, 22 (9), e383
    DOI 10.1016/S1470-2045(21)00400-9, PubMed 34478667
  17. Nakken S, Lilleby W, Switlyk MD, Knudsen KE, Lilleby O, Zhao S, Kaveh F, Ekstrøm PO, Urbanucci A, Hovig E (2021)
    The Quandary of DNA-Based Treatment Assessment in De Novo Metastatic Prostate Cancer in the Era of Precision Oncology
    J Pers Med, 11 (5)
    DOI 10.3390/jpm11050330, PubMed 33922147
  18. Nakken S, Saveliev V, Hofmann O, Møller P, Myklebost O, Hovig E (2021)
    Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
    Int J Cancer, 149 (11), 1955-1960
    DOI 10.1002/ijc.33749, PubMed 34310709
  19. Pavlović M, Scheffer L, Motwani K, Kanduri C, Kompova R, Vazov N, Waagan K, Bernal FLM, Costa AA, Corrie B, Akbar R, Al Hajj GS, Balaban G, Brusko TM, Chernigovskaya M, Christley S, Cowell LG, Frank R, Grytten I, Gundersen S, Haff IH, Hovig E, Hsieh PH, Klambauer G, Kuijjer ML et al. (2021)
    The immuneML ecosystem for machine learning analysis of adaptive immune receptor repertoires
    Nat Mach Intell, 3 (11), 936-944
    DOI 10.1038/s42256-021-00413-z, PubMed 37396030
  20. Schläfli AM, Tokarchuk I, Parejo S, Jutzi S, Berezowska S, Engedal N, Tschan MP (2021)
    ALK inhibition activates LC3B-independent, protective autophagy in EML4-ALK positive lung cancer cells
    Sci Rep, 11 (1), 9011
    DOI 10.1038/s41598-021-87966-6, PubMed 33907223
  21. Seppälä TT, Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2021)
    Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Eur J Cancer, 148, 124-133
    DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481
  22. Seppälä TT, Latchford A, Negoi I, Sampaio Soares A, Jimenez-Rodriguez R, Sánchez-Guillén L, Evans DG, Ryan N, Crosbie EJ, Dominguez-Valentin M, Burn J, Kloor M, Knebel Doeberitz MV, Duijnhoven FJBV, Quirke P, Sampson JR, Møller P, Möslein G, European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP) (2021)
    European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
    Br J Surg, 108 (5), 484-498
    DOI 10.1002/bjs.11902, PubMed 34043773
  23. Solis N, Zavaleta E, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2021)
    Challenges to Bringing Personalized Medicine to a Low-Resource Setting in Peru
    Int J Environ Res Public Health, 18 (4)
    DOI 10.3390/ijerph18041470, PubMed 33557277
  24. Stjepanovic N, Lubinski J, Moller P, Randall Armel S, Foulkes WD, Tung N, Neuhausen SL, Kotsopoulos J, Sun P, Sun S, Eisen A, Narod SA, Hereditary Breast Cancer Clinical Study Group (2021)
    Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 187 (2), 515-523
    DOI 10.1007/s10549-020-06072-9, PubMed 33423179
  25. Sønstevold T, Engedal N, Torgersen ML (2021)
    Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
    Cells, 10 (12)
    DOI 10.3390/cells10123432, PubMed 34943939
  26. Taavitsainen S, Engedal N, Cao S, Handle F, Erickson A, Prekovic S, Wetterskog D, Tolonen T, Vuorinen EM, Kiviaho A, Nätkin R, Häkkinen T, Devlies W, Henttinen S, Kaarijärvi R, Lahnalampi M, Kaljunen H, Nowakowska K, Syvälä H, Bläuer M, Cremaschi P, Claessens F, Visakorpi T, Tammela TLJ, Murtola T et al. (2021)
    Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
    Nat Commun, 12 (1), 5307
    DOI 10.1038/s41467-021-25624-1, PubMed 34489465
  27. Aamdal E, Inderberg EM, Ellingsen EB, Rasch W, Brunsvig PF, Aamdal S, Heintz KM, Vodák D, Nakken S, Hovig E, Nyakas M, Guren TK, Gaudernack G (2021)
    Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
    Front Immunol, 12, 663865
    DOI 10.3389/fimmu.2021.663865, PubMed 34046035

Publications 2020

  1. Ahadova A, Seppälä TT, Engel C, Gallon R, Burn J, Holinski-Feder E, Steinke-Lange V, Möslein G, Nielsen M, Ten Broeke SW, Laghi L, Dominguez-Valentin M, Capella G, Macrae F, Scott R, Hüneburg R, Nattermann J, Hoffmeister M, Brenner H, Bläker H, von Knebel Doeberitz M, Sampson JR, Vasen H, Mecklin JP, Møller P et al. (2020)
    The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance
    Int J Cancer, 148 (4), 800-811
    DOI 10.1002/ijc.33224, PubMed 32683684
  2. Álvarez K, Orellana P, De la Fuente M, Canales T, Pinto E, Heine C, Solar B, Hurtado C, Møller P, Kronberg U, Zarate AJ, Dominguez-Valentin M, López-Köstner F (2020)
    Spectrum and Frequency of Tumors, Cancer Risk and Survival in Chilean Families with Lynch Syndrome: Experience of the Implementation of a Registry
    J Clin Med, 9 (6)
    DOI 10.3390/jcm9061861, PubMed 32549215
  3. Arstad C, Taskén K, Refinetti P, Axcrona U, Giercksky KE, Ekstrøm PO (2020)
    Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer
    Prostate Cancer, 2020, 7673684
    DOI 10.1155/2020/7673684, PubMed 32908706
  4. Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2020)
    Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Genet Med, 23 (4), 705-712
    DOI 10.1038/s41436-020-01029-1, PubMed 33257847
  5. Dominguez-Valentin M, Sampson JR, Møller P, Seppälä TT, PLSD Collaborators (2020)
    Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum
    Int J Cancer, 148 (2), 512-513
    DOI 10.1002/ijc.33214, PubMed 32783184
  6. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2020)
    Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med, 22 (9), 1569
    DOI 10.1038/s41436-020-0892-4, PubMed 32690931
  7. Dominguez-Valentin M, Seppälä TT, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W, Vangala D et al. (2020)
    Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database
    J Clin Med, 9 (7)
    DOI 10.3390/jcm9072290, PubMed 32708519
  8. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D132-D141
    DOI 10.1093/nar/gkz885, PubMed 31598695
  9. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D1172
    DOI 10.1093/nar/gkz1016, PubMed 31642479
  10. Hernández-Sandoval JA, Gutiérrez-Angulo M, Magaña-Torres MT, Alvizo-Rodríguez CR, Ramírez-Plascencia HHF, Flores-López BA, Valenzuela-Pérez JA, Peregrina-Sandoval J, Moreno-Ortiz JM, Domínguez-Valentín M, Ayala-Madrigal ML (2020)
    Prevalence of the BRAF p.v600e variant in patients with colorectal cancer from Mexico and its estimated frequency in Latin American and Caribbean populations
    J Investig Med, 68 (5), 985-991
    DOI 10.1136/jim-2020-001301, PubMed 32184228
  11. Humbert M, Morán M, de la Cruz-Ojeda P, Muntané J, Wiedmer T, Apostolova N, McKenna SL, Velasco G, Balduini W, Eckhart L, Janji B, Sampaio-Marques B, Ludovico P, Žerovnik E, Langer R, Perren A, Engedal N, Tschan MP (2020)
    Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot
    Biology (Basel), 9 (3)
    DOI 10.3390/biology9030059, PubMed 32245178
  12. Itkonen HM, Poulose N, Steele RE, Martin SES, Levine ZG, Duveau DY, Carelli R, Singh R, Urbanucci A, Loda M, Thomas CJ, Mills IG, Walker S (2020)
    Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9
    Mol Cancer Res, 18 (10), 1512-1521
    DOI 10.1158/1541-7786.MCR-20-0339, PubMed 32611550
  13. Kohvakka A, Sattari M, Shcherban A, Annala M, Urbanucci A, Kesseli J, Tammela TLJ, Kivinummi K, Latonen L, Nykter M, Visakorpi T (2020)
    AR and ERG drive the expression of prostate cancer specific long noncoding RNAs
    Oncogene, 39 (30), 5241-5251
    DOI 10.1038/s41388-020-1365-6, PubMed 32555329
  14. Kotsopoulos J, Karlan B, Gronwald J, Hall E, Moller P, Tung N, Zakalik D, Foulkes WD, Rosen B, Neuhausen SL, Sun P, Lubinksi J, Narod SA (2020)
    Long-term outcomes following a diagnosis of ovarian cancer at the time of preventive oophorectomy among BRCA1 and BRCA2 mutation carriers
    Int J Gynecol Cancer, 30 (6), 825-830
    DOI 10.1136/ijgc-2019-001141, PubMed 32354794
  15. Lavelle TJ, Alver TN, Heintz KM, Wernhoff P, Nygaard V, Nakken S, Øy GF, Bøe SL, Urbanucci A, Hovig E (2020)
    Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes
    Cancers (Basel), 12 (7)
    DOI 10.3390/cancers12071719, PubMed 32605315
  16. Møller P (2020)
    The Prospective Lynch Syndrome Database reports enable evidence-based personal precision health care
    Hered Cancer Clin Pract, 18, 6
    DOI 10.1186/s13053-020-0138-0, PubMed 32190163
  17. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2020)
    Correction: Møller, P.; et al. Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift. Cancers 2019, 11, 132
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020410, PubMed 32050665
  18. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2020)
    Letter to the Editor-Recent advances in Lynch syndrome
    Fam Cancer, 20 (2), 117-118
    DOI 10.1007/s10689-020-00200-6, PubMed 32770425
  19. Olafsdottir EJ, Borg A, Jensen MB, Gerdes AM, Johansson ALV, Barkardottir RB, Johannsson OT, Ejlertsen B, Sønderstrup IMH, Hovig E, Lænkholm AV, Hansen TVO, Olafsdottir GH, Rossing M, Jonasson JG, Sigurdsson S, Loman N, Nilsson MP, Narod SA, Tryggvadottir L (2020)
    Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
    Br J Cancer, 123 (11), 1608-1615
    DOI 10.1038/s41416-020-01056-4, PubMed 32939053
  20. Pace M, Falappa M, Freschi A, Balzani E, Berteotti C, Lo Martire V, Kaveh F, Hovig E, Zoccoli G, Amici R, Cerri M, Urbanucci A, Tucci V (2020)
    Loss of Snord116 impacts lateral hypothalamus, sleep, and food-related behaviors
    JCI Insight, 5 (12)
    DOI 10.1172/jci.insight.137495, PubMed 32365348
  21. Piñero TA, Soukarieh O, Rolain M, Alvarez K, López-Köstner F, Torrezan GT, Carraro DM, De Oliveira Nascimento IL, Bomfim TF, Machado-Lopes TMB, Freitas JC, Toralles MB, Sandes KA, Rossi BM, Junior SA, Meira J, Dominguez-Valentin M, Møller P, Vaccaro CA, Martins A, Pavicic WH (2020)
    MLH1 intronic variants mapping to + 5 position of splice donor sites lead to deleterious effects on RNA splicing
    Fam Cancer, 19 (4), 323-336
    DOI 10.1007/s10689-020-00182-5, PubMed 32363481
  22. Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
    Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
    Acta Oncol, 59 (7), 733-740
    DOI 10.1080/0284186X.2020.1742377, PubMed 32208873
  23. Refinetti P, Morgenthaler S, Thilly WG, Arstad C, Ekstrøm PO (2020)
    Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations
    Front Oncol, 10, 523860
    DOI 10.3389/fonc.2020.523860, PubMed 33344219
  24. Salgado D, Armean IM, Baudis M, Beltran S, Capella-Gutierrez S, Carvalho-Silva D, Dominguez Del Angel V, Dopazo J, Furlong LI, Gao B, Garcia L, Gerloff D, Gut I, Gyenesei A, Habermann N, Hancock JM, Hanauer M, Hovig E, Johansson LF, Keane T, Korbel J, Lauer KB, Laurie S, Leskošek B, Lloyd D et al. (2020)
    The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research
    F1000Res, 9
    DOI 10.12688/f1000research.24887.1, PubMed 34367618
  25. Seppälä TT, Dominguez-Valentin M, Sampson JR, Møller P (2020)
    Prospective observational data informs understanding and future management of Lynch syndrome: insights from the Prospective Lynch Syndrome Database (PLSD)
    Fam Cancer, 20 (1), 35-39
    DOI 10.1007/s10689-020-00193-2, PubMed 32507935
  26. Sønstevold T, Engedal N, Mørch Ý, Iversen TG, Skotland T, Sandvig K, Torgersen ML (2020)
    Structural Variants of poly(alkylcyanoacrylate) Nanoparticles Differentially Affect LC3 and Autophagic Cargo Degradation
    J Biomed Nanotechnol, 16 (4), 432-445
    DOI 10.1166/jbn.2020.2906, PubMed 32970976
  27. Wise JF, Nakken S, Steen CB, Vodák D, Trøen G, Johannessen B, Lingjærde OC, Hilden V, Blaker YN, Bai B, Aasheim LB, Pasanen A, Lorenz S, Sveen A, Lothe RA, Myklebost O, Leppä S, Meza-Zepeda LA, Beiske K, Lawrence MS, Hovig E, Myklebust JH, Smeland EB, Holte H (2020)
    Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series
    Blood Adv, 4 (9), 1859-1866
    DOI 10.1182/bloodadvances.2019001325, PubMed 32374878
  28. Waaler J, Mygland L, Tveita A, Strand MF, Solberg NT, Olsen PA, Aizenshtadt A, Fauskanger M, Lund K, Brinch SA, Lycke M, Dybing E, Nygaard V, Bøe SL, Heintz KM, Hovig E, Hammarström C, Corthay A, Krauss S (2020)
    Tankyrase inhibition sensitizes melanoma to PD-1 immune checkpoint blockade in syngeneic mouse models
    Commun Biol, 3 (1), 196
    DOI 10.1038/s42003-020-0916-2, PubMed 32332858
  29. Zhao S, Agafonov O, Azab A, Stokowy T, Hovig E (2020)
    Accuracy and efficiency of germline variant calling pipelines for human genome data
    Sci Rep, 10 (1), 20222
    DOI 10.1038/s41598-020-77218-4, PubMed 33214604

Publications 2019

  1. Braadland PR, Ramberg H, Grytli HH, Urbanucci A, Nielsen HK, Guldvik IJ, Engedal A, Ketola K, Wang W, Svindland A, Mills IG, Bjartell A, Taskén KA (2019)
    The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells
    Mol Cancer Res, 17 (11), 2154-2168
    DOI 10.1158/1541-7786.MCR-18-0605, PubMed 31395667
  2. Braadland PR, Urbanucci A (2019)
    Chromatin reprogramming as an adaptation mechanism in advanced prostate cancer
    Endocr Relat Cancer, 26 (4), R211-R235
    DOI 10.1530/ERC-18-0579, PubMed 30844748
  3. Crosbie EJ, Ryan NAJ, Arends MJ, Bosse T, Burn J, Cornes JM, Crawford R, Eccles D, Frayling IM, Ghaem-Maghami S, Hampel H, Kauff ND, Kitchener HC, Kitson SJ, Manchanda R, McMahon RFT, Monahan KJ, Menon U, Møller P, Möslein G, Rosenthal A, Sasieni P, Seif MW, Singh N, Skarrott P et al. (2019)
    The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome
    Genet Med, 21 (10), 2390-2400
    DOI 10.1038/s41436-019-0489-y, PubMed 30918358
  4. Della Valle A, Rossi BM, Palmero EI, Antelo M, Vaccaro CA, López-Kostner F, Alvarez K, Cruz-Correa M, Bruno LI, Forones NM, Mindiola JAR, Buleje J, Spirandelli F, Bohorquez M, Cock-Rada AM, Sullcahuaman Y, Nascimento I, Abe-Sandes K, Lino-Silva LS, Petracchi F, Mampel A, Rodriguez Y, Rossi NT, Yañez CB, Rubio C et al. (2019)
    A snapshot of current genetic testing practice in Lynch syndrome: The results of a representative survey of 33 Latin American existing centres/registries
    Eur J Cancer, 119, 112-121
    DOI 10.1016/j.ejca.2019.07.017, PubMed 31442815
  5. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Holth A, Capella G, Davidson B, Evans DG, Martins A, Møller P, Hovig E (2019)
    Results of multigene panel testing in familial cancer cases without genetic cause demonstrated by single gene testing
    Sci Rep, 9 (1), 18555
    DOI 10.1038/s41598-019-54517-z, PubMed 31811167
  6. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2019)
    Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med, 22 (1), 15-25
    DOI 10.1038/s41436-019-0596-9, PubMed 31337882
  7. Dominguez-Valentin M, Seppälä TT, Sampson JR, Macrae F, Winship I, Evans DG, Scott RJ, Burn J, Möslein G, Bernstein I, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lindblom A, Plazzer JP, Tjandra D, Thomas H, Green K, Lalloo F, Crosbie EJ, Hill J, Capella G, Pineda M, Navarro M, Vidal JB et al. (2019)
    Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report
    Hered Cancer Clin Pract, 17, 28
    DOI 10.1186/s13053-019-0127-3, PubMed 31636762
  8. Handle F, Prekovic S, Helsen C, Van den Broeck T, Smeets E, Moris L, Eerlings R, Kharraz SE, Urbanucci A, Mills IG, Joniau S, Attard G, Claessens F (2019)
    Drivers of AR indifferent anti-androgen resistance in prostate cancer cells
    Sci Rep, 9 (1), 13786
    DOI 10.1038/s41598-019-50220-1, PubMed 31551480
  9. Itkonen HM, Urbanucci A, Martin SE, Khan A, Mathelier A, Thiede B, Walker S, Mills IG (2019)
    High OGT activity is essential for MYC-driven proliferation of prostate cancer cells
    Theranostics, 9 (8), 2183-2197
    DOI 10.7150/thno.30834, PubMed 31149037
  10. Kanduri C, Bock C, Gundersen S, Hovig E, Sandve GK (2019)
    Colocalization analyses of genomic elements: approaches, recommendations and challenges
    Bioinformatics, 35 (9), 1615-1624
    DOI 10.1093/bioinformatics/bty835, PubMed 30307532
  11. Kotsopoulos J, Lubinski J, Lynch HT, Tung N, Armel S, Senter L, Singer CF, Fruscio R, Couch F, Weitzel JN, Karlan B, Foulkes WD, Moller P, Eisen A, Ainsworth P, Neuhausen SL, Olopade O, Sun P, Gronwald J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2019)
    Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers
    Breast Cancer Res Treat, 175 (2), 443-449
    DOI 10.1007/s10549-019-05162-7, PubMed 30756284
  12. Lund-Andersen C, Nakken S, Nygård S, Fromm B, Aasheim LB, Davidson B, Julsrud L, Abrahamsen TW, Kristensen AT, Dybdahl B, Larsen SG, Hovig E, Flatmark K (2019)
    Integrative genomic analysis of peritoneal malignant mesothelioma: understanding a case with extraordinary chemotherapy response
    Cold Spring Harb Mol Case Stud, 5 (2)
    DOI 10.1101/mcs.a003566, PubMed 30862609
  13. Metcalfe K, Eisen A, Senter L, Armel S, Bordeleau L, Meschino WS, Pal T, Lynch HT, Tung NM, Kwong A, Ainsworth P, Karlan B, Moller P, Eng C, Weitzel JN, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2019)
    International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation
    Br J Cancer, 121 (1), 15-21
    DOI 10.1038/s41416-019-0446-1, PubMed 30971774
  14. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2019)
    Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift
    Cancers (Basel), 11 (2)
    DOI 10.3390/cancers11020132, PubMed 30678073
  15. Njølstad PR, Andreassen OA, Brunak S, Børglum AD, Dillner J, Esko T, Franks PW, Freimer N, Groop L, Heimer H, Hougaard DM, Hovig E, Hveem K, Jalanko A, Kaprio J, Knudsen GP, Melbye M, Metspalu A, Mortensen PB, Palmgren J, Palotie A, Reed W, Stefánsson H, Stitziel NO, Sullivan PF et al. (2019)
    Roadmap for a precision-medicine initiative in the Nordic region
    Nat Genet, 51 (6), 924-930
    DOI 10.1038/s41588-019-0391-1, PubMed 30988515
  16. Nygård S, Lingjærde OC, Caldas C, Hovig E, Børresen-Dale AL, Helland Å, Haakensen VD (2019)
    PathTracer: High-sensitivity detection of differential pathway activity in tumours
    Sci Rep, 9 (1), 16332
    DOI 10.1038/s41598-019-52529-3, PubMed 31704995
  17. Pashov A, Shivarov V, Hadzhieva M, Kostov V, Ferdinandov D, Heintz KM, Pashova S, Todorova M, Vassilev T, Kieber-Emmons T, Meza-Zepeda LA, Hovig E (2019)
    Diagnostic Profiling of the Human Public IgM Repertoire With Scalable Mimotope Libraries
    Front Immunol, 10, 2796
    DOI 10.3389/fimmu.2019.02796, PubMed 31849974
  18. Ree AH, Nygaard V, Russnes HG, Heinrich D, Nygaard V, Johansen C, Bergheim IR, Hovig E, Beiske K, Negård A, Børresen-Dale AL, Flatmark K, Mælandsmo GM (2019)
    Responsiveness to PD-1 Blockade in End-Stage Colon Cancer with Gene Locus 9p24.1 Copy-Number Gain
    Cancer Immunol Res, 7 (5), 701-706
    DOI 10.1158/2326-6066.CIR-18-0777, PubMed 30804006
  19. Sampson JR, Dominguez-Valentin M, Seppälä TT, Møller P (2019)
    Response to Tolva et al
    Genet Med, 22 (4), 813-814
    DOI 10.1038/s41436-019-0717-5, PubMed 31801985
  20. Seppälä TT, Ahadova A, Dominguez-Valentin M, Macrae F, Evans DG, Therkildsen C, Sampson J, Scott R, Burn J, Möslein G, Bernstein I, Holinski-Feder E, Pylvänäinen K, Renkonen-Sinisalo L, Lepistö A, Lautrup CK, Lindblom A, Plazzer JP, Winship I, Tjandra D, Katz LH, Aretz S, Hüneburg R, Holzapfel S, Heinimann K et al. (2019)
    Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report
    Hered Cancer Clin Pract, 17, 8
    DOI 10.1186/s13053-019-0106-8, PubMed 30858900
  21. Ten Broeke SW, Rodríguez-Girondo M, Suerink M, Aretz S, Bernstein I, Capellá G, Engel C, Gomez-Garcia EB, van Hest LP, von Knebel Doeberitz M, Lagerstedt-Robinson K, Letteboer TGW, Moller P, van Os TA, Pineda M, Rahner N, Olderode-Berends MJW, von Salomé J, Schackert HK, Spruijt L, Steinke-Lange V, Wagner A, Tops CMJ, Nielsen M (2019)
    The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect
    Cancer Epidemiol Biomarkers Prev, 28 (6), 1010-1014
    DOI 10.1158/1055-9965.EPI-18-0576, PubMed 30824524
  22. Tolios A, De Las Rivas J, Hovig E, Trouillas P, Scorilas A, Mohr T (2019)
    Computational approaches in cancer multidrug resistance research: Identification of potential biomarkers, drug targets and drug-target interactions
    Drug Resist Updat, 48, 100662
    DOI 10.1016/j.drup.2019.100662, PubMed 31927437

Publications 2018

  1. Birkeland E, Zhang S, Poduval D, Geisler J, Nakken S, Vodak D, Meza-Zepeda LA, Hovig E, Myklebost O, Knappskog S, Lønning PE (2018)
    Patterns of genomic evolution in advanced melanoma
    Nat Commun, 9 (1), 2665
    DOI 10.1038/s41467-018-05063-1, PubMed 29991680
  2. Dominguez-Valentin M, Evans DGR, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds
    Hered Cancer Clin Pract, 16, 4
    DOI 10.1186/s13053-018-0086-0, PubMed 29371908
  3. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families
    Fam Cancer, 17 (1), 141-153
    DOI 10.1007/s10689-017-0011-0, PubMed 28608266
  4. Dominguez-Valentin M, Nakken S, Tubeuf H, Vodak D, Ekstrøm PO, Nissen AM, Morak M, Holinski-Feder E, Martins A, Møller P, Hovig E (2018)
    Identification of genetic variants for clinical management of familial colorectal tumors
    BMC Med Genet, 19 (1), 26
    DOI 10.1186/s12881-018-0533-9, PubMed 29458332
  5. Ebenesersdóttir SS, Sandoval-Velasco M, Gunnarsdóttir ED, Jagadeesan A, Guðmundsdóttir VB, Thordardóttir EL, Einarsdóttir MS, Moore KHS, Sigurðsson Á, Magnúsdóttir DN, Jónsson H, Snorradóttir S, Hovig E, Møller P, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Cavalleri GL, Gilbert E, Lalueza-Fox C, Walser JW, Kristjánsdóttir S, Gopalakrishnan S et al. (2018)
    Ancient genomes from Iceland reveal the making of a human population
    Science, 360 (6392), 1028-1032
    DOI 10.1126/science.aar2625, PubMed 29853688
  6. González ML, Causada-Calo N, Santino JP, Dominguez-Valentin M, Ferro FA, Sammartino I, Kalfayan PG, Verzura MA, Piñero TA, Cajal AR, Pavicic W, Vaccaro C (2018)
    Universal determination of microsatellite instability using BAT26 as a single marker in an Argentine colorectal cancer cohort
    Fam Cancer, 17 (3), 395-402
    DOI 10.1007/s10689-017-0052-4, PubMed 29128931
  7. Ibrahim I, Dominguez-Valentin M, Segal B, Zeitouni A, da Silva SD (2018)
    Mitochondrial mutations associated with hearing and balance disorders
    Mutat Res, 810, 39-44
    DOI 10.1016/j.mrfmmm.2018.03.003, PubMed 29615272
  8. Kim SJ, Huzarski T, Gronwald J, Singer CF, Møller P, Lynch HT, Armel S, Karlan BY, Foulkes WD, Neuhausen SL, Senter L, Eisen A, Eng C, Panchal S, Pal T, Olopade O, Zakalik D, Lubinski J, Narod SA, Kotsopoulos J, (2018)
    Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers
    Int J Epidemiol, 47 (3), 987-997
    DOI 10.1093/ije/dyy039, PubMed 29547931
  9. Kotsopoulos J, Gronwald J, Karlan B, Rosen B, Huzarski T, Moller P, Lynch HT, Singer CF, Senter L, Neuhausen SL, Tung N, Eisen A, Foulkes WD, Ainsworth P, Sun P, Lubinski J, Narod SA, Hereditary Ovarian Cancer Clinical Study Group (2018)
    Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 150 (1), 85-91
    DOI 10.1016/j.ygyno.2018.05.011, PubMed 29793803
  10. Kotsopoulos J, Gronwald J, Karlan BY, Huzarski T, Tung N, Moller P, Armel S, Lynch HT, Senter L, Eisen A, Singer CF, Foulkes WD, Jacobson MR, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2018)
    Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers
    JAMA Oncol, 4 (8), 1059-1065
    DOI 10.1001/jamaoncol.2018.0211, PubMed 29710224
  11. Köger N, Paulsen L, López-Kostner F, Della Valle A, Vaccaro CA, Palmero EI, Alvarez K, Sarroca C, Neffa F, Kalfayan PG, Gonzalez ML, Rossi BM, Reis RM, Brieger A, Zeuzem S, Hinrichsen I, Dominguez-Valentin M, Plotz G (2018)
    Evaluation of MLH1 variants of unclear significance
    Genes Chromosomes Cancer, 57 (7), 350-358
    DOI 10.1002/gcc.22536, PubMed 29520894
  12. Møller P, Hovig E (2018)
    Retraction Note to: The BRCA2 variant c.68-7 T > A is associated with breast cancer
    Hered Cancer Clin Pract, 16, 10
    DOI 10.1186/s13053-018-0093-1, PubMed 29745381
  13. Ten Broeke SW, van der Klift HM, Tops CMJ, Aretz S, Bernstein I, Buchanan DD, de la Chapelle A, Capella G, Clendenning M, Engel C, Gallinger S, Gomez Garcia E, Figueiredo JC, Haile R, Hampel HL, Hopper JL, Hoogerbrugge N, von Knebel Doeberitz M, Le Marchand L, Letteboer TGW, Jenkins MA, Lindblom A, Lindor NM, Mensenkamp AR, Møller P et al. (2018)
    Cancer Risks for PMS2-Associated Lynch Syndrome
    J Clin Oncol, 36 (29), 2961-2968
    DOI 10.1200/JCO.2018.78.4777, PubMed 30161022
  14. Vaccaro CA, López-Kostner F, Adriana DV, Palmero EI, Rossi BM, Antelo M, Solano A, Carraro DM, Forones NM, Bohorquez M, Lino-Silva LS, Buleje J, Spirandelli F, Abe-Sandes K, Nascimento I, Sullcahuaman Y, Sarroca C, Gonzalez ML, Herrando AI, Alvarez K, Neffa F, Galvão HC, Esperon P, Golubicki M, Cisterna D et al. (2018)
    From colorectal cancer pattern to the characterization of individuals at risk: Picture for genetic research in Latin America
    Int J Cancer, 145 (2), 318-326
    DOI 10.1002/ijc.31920, PubMed 30303536
  15. Vodák D, Lorenz S, Nakken S, Aasheim LB, Holte H, Bai B, Myklebost O, Meza-Zepeda LA, Hovig E (2018)
    Sample-Index Misassignment Impacts Tumour Exome Sequencing
    Sci Rep, 8 (1), 5307
    DOI 10.1038/s41598-018-23563-4, PubMed 29593270

Publications 2017

  1. Arstad C, Refinetti P, Kristensen AT, Giercksky KE, Ekstrøm PO (2017)
    Is detection of intraperitoneal exfoliated tumor cells after surgical resection of rectal cancer a prognostic factor of survival?
    BMC Cancer, 17 (1), 406
    DOI 10.1186/s12885-017-3365-7, PubMed 28592327
  2. Clancy T, Dannenfelser R, Troyanskaya O, Malmberg KJ, Hovig E, Kristensen V (2017)
    Bioinformatics Approaches to Profile the Tumor Microenvironment for Immunotherapeutic Discovery
    Curr Pharm Des, 23 (32), 4716-4725
    DOI 10.2174/1381612823666170710154936, PubMed 28699527
  3. Domanska D, Vodák D, Lund-Andersen C, Salvatore S, Hovig E, Sandve GK (2017)
    The rainfall plot: its motivation, characteristics and pitfalls
    BMC Bioinformatics, 18 (1), 264
    DOI 10.1186/s12859-017-1679-8, PubMed 28521741
  4. Helland Å, Brustugun OT, Nakken S, Halvorsen AR, Dønnem T, Bremnes R, Busund LT, Sun J, Lorenz S, Solberg SK, Jørgensen LH, Vodak D, Myklebost O, Hovig E, Meza-Zepeda LA (2017)
    High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival
    Int J Cancer, 141 (1), 184-190
    DOI 10.1002/ijc.30726, PubMed 28387924
  5. Kanduri C, Domanska D, Hovig E, Sandve GK (2017)
    Genome build information is an essential part of genomic track files
    Genome Biol, 18 (1), 175
    DOI 10.1186/s13059-017-1312-1, PubMed 28911336
  6. Meisal R, Rounge TB, Christiansen IK, Eieland AK, Worren MM, Molden TF, Kommedal Ø, Hovig E, Leegaard TM, Ambur OH (2017)
    HPV Genotyping of Modified General Primer-Amplicons Is More Analytically Sensitive and Specific by Sequencing than by Hybridization
    PLoS One, 12 (1), e0169074
    DOI 10.1371/journal.pone.0169074, PubMed 28045981
  7. Møller P, Hovig E (2017)
    The BRCA2 variant c.68-7 T>A is associated with breast cancer
    Hered Cancer Clin Pract, 15, 20 (Retracted)
    DOI 10.1186/s13053-017-0080-y, PubMed 29158857
  8. Møller P, Seppälä TT, Bernstein I, Holinski-Feder E, Sala P, Gareth Evans D, Lindblom A, Macrae F, Blanco I, Sijmons RH, Jeffries J, Vasen HFA, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen JT, Jenkins MA, Green K, Lalloo F, Sunde L, Mints M et al. (2017)
    Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
    Gut, 67 (7), 1306-1316
    DOI 10.1136/gutjnl-2017-314057, PubMed 28754778
  9. Namløs HM, Zaikova O, Bjerkehagen B, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2017)
    Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report
    BMC Cancer, 17 (1), 29
    DOI 10.1186/s12885-016-2992-8, PubMed 28061772
  10. Nygaard V, Rødland EA, Hovig E (2017)
    Reply to Towfic and others' letter to the editor
    Biostatistics, 18 (3), 586-587
    DOI 10.1093/biostatistics/kxx001, PubMed 28334081
  11. Ree AH, Russnes HG, Heinrich D, Dueland S, Boye K, Nygaard V, Silwal-Pandit L, Østrup O, Hovig E, Nygaard V, Rødland EA, Nakken S, Øien JT, Johansen C, Bergheim IR, Skarpeteig V, Sathermugathevan M, Sauer T, Lund-Iversen M, Beiske K, Nasser S, Julsrud L, Reisse CH, Ruud EA, Flørenes VA et al. (2017)
    Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate
    ESMO Open, 2 (2), e000158
    DOI 10.1136/esmoopen-2017-000158, PubMed 28761742
  12. Refinetti P, Arstad C, Thilly WG, Morgenthaler S, Ekstrøm PO (2017)
    Mapping mitochondrial heteroplasmy in a Leydig tumor by laser capture micro-dissection and cycling temperature capillary electrophoresis
    BMC Clin Pathol, 17, 6
    DOI 10.1186/s12907-017-0042-3, PubMed 28405177
  13. Rossi BM, Palmero EI, López-Kostner F, Sarroca C, Vaccaro CA, Spirandelli F, Ashton-Prolla P, Rodriguez Y, de Campos Reis Galvão H, Reis RM, Escremim de Paula A, Capochin Romagnolo LG, Alvarez K, Della Valle A, Neffa F, Kalfayan PG, Spirandelli E, Chialina S, Gutiérrez Angulo M, Castro-Mujica MDC, Sanchez de Monte J, Quispe R, da Silva SD, Rossi NT, Barletta-Carrillo C et al. (2017)
    A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
    BMC Cancer, 17 (1), 623
    DOI 10.1186/s12885-017-3599-4, PubMed 28874130
  14. Seppälä T, Pylvänäinen K, Evans DG, Järvinen H, Renkonen-Sinisalo L, Bernstein I, Holinski-Feder E, Sala P, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Genuardi M, Green K et al. (2017)
    Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report
    Hered Cancer Clin Pract, 15, 18
    DOI 10.1186/s13053-017-0078-5, PubMed 29046738
  15. Simovski B, Vodák D, Gundersen S, Domanska D, Azab A, Holden L, Holden M, Grytten I, Rand K, Drabløs F, Johansen M, Mora A, Lund-Andersen C, Fromm B, Eskeland R, Gabrielsen OS, Ferkingstad E, Nakken S, Bengtsen M, Nederbragt AJ, Thorarensen HS, Akse JA, Glad I, Hovig E, Sandve GK (2017)
    GSuite HyperBrowser: integrative analysis of dataset collections across the genome and epigenome
    Gigascience, 6 (7), 1-12
    DOI 10.1093/gigascience/gix032, PubMed 28459977

Publications 2016

  1. Alver TN, Lavelle TJ, Longva AS, Øy GF, Hovig E, Bøe SL (2016)
    MITF depletion elevates expression levels of ERBB3 receptor and its cognate ligand NRG1-beta in melanoma
    Oncotarget, 7 (34), 55128-55140
    DOI 10.18632/oncotarget.10422, PubMed 27391157
  2. Arstad C, Refinetti P, Warren D, Giercksky KE, Ekstrøm PO (2016)
    Scanning the mitochondrial genome for mutations by cycling temperature capillary electrophoresis
    Mitochondrial DNA A DNA Mapp Seq Anal, 29 (1), 19-30
    DOI 10.1080/24701394.2016.1233532, PubMed 27728990
  3. Björklund AT, Clancy T, Goodridge JP, Béziat V, Schaffer M, Hovig E, Ljunggren HG, Ljungman PT, Malmberg KJ (2016)
    Naive Donor NK Cell Repertoires Associated with Less Leukemia Relapse after Allogeneic Hematopoietic Stem Cell Transplantation
    J Immunol, 196 (3), 1400-11
    DOI 10.4049/jimmunol.1501434, PubMed 26746188
  4. Børnich C, Grytten I, Hovig E, Paulsen J, Čech M, Sandve GK (2016)
    Galaxy Portal: interacting with the galaxy platform through mobile devices
    Bioinformatics, 32 (11), 1743-5
    DOI 10.1093/bioinformatics/btw042, PubMed 26819474
  5. Clancy T, Hovig E (2016)
    Profiling networks of distinct immune-cells in tumors
    BMC Bioinformatics, 17 (1), 263
    DOI 10.1186/s12859-016-1141-3, PubMed 27377892
  6. DA Silva FC, Wernhoff P, Dominguez-Barrera C, Dominguez-Valentin M (2016)
    Update on Hereditary Colorectal Cancer
    Anticancer Res, 36 (9), 4399-405
    DOI 10.21873/anticanres.10983, PubMed 27630275
  7. Di Stefano M, Paulsen J, Lien TG, Hovig E, Micheletti C (2016)
    Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization
    Sci Rep, 6, 35985
    DOI 10.1038/srep35985, PubMed 27786255
  8. Dominguez-Valentin M, Wernhoff P, Cajal AR, Kalfayan PG, Piñero TA, Gonzalez ML, Ferro A, Sammartino I, Causada Calo NS, Vaccaro CA (2016)
    MLH1 Ile219Val Polymorphism in Argentinean Families with Suspected Lynch Syndrome
    Front Oncol, 6, 189
    DOI 10.3389/fonc.2016.00189, PubMed 27606285
  9. Halvorsen AR, Silwal-Pandit L, Meza-Zepeda LA, Vodak D, Vu P, Sagerup C, Hovig E, Myklebost O, Børresen-Dale AL, Brustugun OT, Helland Å (2016)
    TP53 Mutation Spectrum in Smokers and Never Smoking Lung Cancer Patients
    Front Genet, 7, 85
    DOI 10.3389/fgene.2016.00085, PubMed 27242894
  10. Haugvik SP, Vodák D, Haugom L, Hovig E, Gladhaug IP, Heim S, Micci F (2016)
    Transcriptomic Profiling of Tumor Aggressiveness in Sporadic Nonfunctioning Pancreatic Neuroendocrine Neoplasms
    Pancreas, 45 (8), 1196-203
    DOI 10.1097/MPA.0000000000000610, PubMed 26918873
  11. Haakensen VD, Nygaard V, Greger L, Aure MR, Fromm B, Bukholm IR, Lüders T, Chin SF, Git A, Caldas C, Kristensen VN, Brazma A, Børresen-Dale AL, Hovig E, Helland Å (2016)
    Subtype-specific micro-RNA expression signatures in breast cancer progression
    Int J Cancer, 139 (5), 1117-28
    DOI 10.1002/ijc.30142, PubMed 27082076
  12. Jonsson M, Ragnum HB, Julin CH, Yeramian A, Clancy T, Frikstad KM, Seierstad T, Stokke T, Matias-Guiu X, Ree AH, Flatmark K, Lyng H (2016)
    Hypoxia-independent gene expression signature associated with radiosensitisation of prostate cancer cell lines by histone deacetylase inhibition
    Br J Cancer, 115 (8), 929-939
    DOI 10.1038/bjc.2016.278, PubMed 27599042
  13. Joshi S, Schjølberg AR, Ekstrøm PO, De Angelis PM, Zucknick M, Andersen SN, Clausen OP (2016)
    Tp53/p53 status in keratoacanthomas
    J Cutan Pathol, 43 (7), 571-8
    DOI 10.1111/cup.12713, PubMed 27020606
  14. Landfors M, Nakken S, Fusser M, Dahl JA, Klungland A, Fedorcsak P (2016)
    Sequencing of FTO and ALKBH5 in men undergoing infertility work-up identifies an infertility-associated variant and two missense mutations
    Fertil Steril, 105 (5), 1170-1179.e5
    DOI 10.1016/j.fertnstert.2016.01.002, PubMed 26820768
  15. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Jenkins M, Green K, Lalloo F, Sunde L, Mints M et al. (2016)
    Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
    Gut, 66 (9), 1657-1664
    DOI 10.1136/gutjnl-2016-311403, PubMed 27261338
  16. Späth F, Andersson U, Dahlin AM, Langseth H, Hovig E, Johannesen TB, Grankvist K, Björkblom B, Wibom C, Melin B (2016)
    Pre-diagnostic serum levels of EGFR and ErbB2 and genetic glioma risk variants: a nested case-control study
    Tumour Biol, 37 (8), 11065-72
    DOI 10.1007/s13277-015-4742-y, PubMed 26906551
  17. Vaccaro CA, Sarroca C, Rossi B, Lopez-Kostner F, Dominguez M, Calo NC, Cutait R, Valle AD, Nuñez L, Neffa F, Alvarez K, Gonzalez ML, Kalfayan P, Lynch HT, Church J (2016)
    Lynch syndrome in South America: past, present and future
    Fam Cancer, 15 (3), 437-45
    DOI 10.1007/s10689-016-9903-7, PubMed 27007491

Publications 2015

  1. Alioto TS, Buchhalter I, Derdak S, Hutter B, Eldridge MD, Hovig E, Heisler LE, Beck TA, Simpson JT, Tonon L, Sertier AS, Patch AM, Jäger N, Ginsbach P, Drews R, Paramasivam N, Kabbe R, Chotewutmontri S, Diessl N, Previti C, Schmidt S, Brors B, Feuerbach L, Heinold M, Gröbner S et al. (2015)
    A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
    Nat Commun, 6, 10001
    DOI 10.1038/ncomms10001, PubMed 26647970
  2. Bengtsen M, Klepper K, Gundersen S, Cuervo I, Drabløs F, Hovig E, Sandve GK, Gabrielsen OS, Eskeland R (2015)
    c-Myb Binding Sites in Haematopoietic Chromatin Landscapes
    PLoS One, 10 (7), e0133280
    DOI 10.1371/journal.pone.0133280, PubMed 26208222
  3. Christiansen IK, Sandve GK, Schmitz M, Dürst M, Hovig E (2015)
    Transcriptionally active regions are the preferred targets for chromosomal HPV integration in cervical carcinogenesis
    PLoS One, 10 (3), e0119566
    DOI 10.1371/journal.pone.0119566, PubMed 25793388
  4. Ekstrøm PO, Nakken S, Johansen M, Hovig E (2015)
    Automated amplicon design suitable for analysis of DNA variants by melting techniques
    BMC Res Notes, 8, 667
    DOI 10.1186/s13104-015-1624-8, PubMed 26559640
  5. Heramb C, Ekstrøm PO, Tharmaratnam K, Hovig E, Møller P, Mæhle L (2015)
    Ten modifiers of BRCA1 penetrance validated in a Norwegian series
    Hered Cancer Clin Pract, 13 (1), 14
    DOI 10.1186/s13053-015-0035-0, PubMed 26052370
  6. Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
    PLoS One, 10 (2), e0117261
    DOI 10.1371/journal.pone.0117261, PubMed 25706641
  7. Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
    Genom Data, 5, 176-83
    DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252
  8. Møller P, Seppälä T, Bernstein I, Holinski-Feder E, Sala P, Evans DG, Lindblom A, Macrae F, Blanco I, Sijmons R, Jeffries J, Vasen H, Burn J, Nakken S, Hovig E, Rødland EA, Tharmaratnam K, de Vos Tot Nederveen Cappel WH, Hill J, Wijnen J, Green K, Lalloo F, Sunde L, Mints M, Bertario L et al. (2015)
    Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
    Gut, 66 (3), 464-472
    DOI 10.1136/gutjnl-2015-309675, PubMed 26657901
  9. Nygaard V, Rødland EA, Hovig E (2015)
    Methods that remove batch effects while retaining group differences may lead to exaggerated confidence in downstream analyses
    Biostatistics, 17 (1), 29-39
    DOI 10.1093/biostatistics/kxv027, PubMed 26272994
  10. Rustad EH, Dai HY, Hov H, Coward E, Beisvag V, Myklebost O, Hovig E, Nakken S, Vodák D, Meza-Zepeda LA, Sandvik AK, Wader KF, Misund K, Sundan A, Aarset H, Waage A (2015)
    BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis
    Blood Cancer J, 5 (3), e299
    DOI 10.1038/bcj.2015.24, PubMed 25794135
  11. Rydbeck H, Sandve GK, Ferkingstad E, Simovski B, Rye M, Hovig E (2015)
    ClusTrack: feature extraction and similarity measures for clustering of genome-wide data sets
    PLoS One, 10 (4), e0123261
    DOI 10.1371/journal.pone.0123261, PubMed 25879845
  12. Wibom C, Späth F, Dahlin AM, Langseth H, Hovig E, Rajaraman P, Johannesen TB, Andersson U, Melin B (2015)
    Investigation of established genetic risk variants for glioma in prediagnostic samples from a population-based nested case-control study
    Cancer Epidemiol Biomarkers Prev, 24 (5), 810-6
    DOI 10.1158/1055-9965.EPI-14-1106, PubMed 25713050

Publications 2014

  1. Chilamakuri CS, Lorenz S, Madoui MA, Vodák D, Sun J, Hovig E, Myklebost O, Meza-Zepeda LA (2014)
    Performance comparison of four exome capture systems for deep sequencing
    BMC Genomics, 15 (1), 449
    DOI 10.1186/1471-2164-15-449, PubMed 24912484
  2. Clancy T, Hovig E (2014)
    From proteomes to complexomes in the era of systems biology
    Proteomics, 14 (1), 24-41
    DOI 10.1002/pmic.201300230, PubMed 24243660
  3. Clancy T, Hovig E (2014)
    Differential protein network analysis of the immune cell lineage
    Biomed Res Int, 2014, 363408
    DOI 10.1155/2014/363408, PubMed 25309909
  4. Friis-Ottessen M, Burum-Auensen E, Schjølberg AR, Ekstrøm PO, Andersen SN, Clausen OP, De Angelis PM (2014)
    TP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitis
    Int J Mol Med, 35 (1), 24-30
    DOI 10.3892/ijmm.2014.1974, PubMed 25333414
  5. Nygård S, Reitan T, Clancy T, Nygaard V, Bjørnstad J, Skrbic B, Tønnessen T, Christensen G, Hovig E (2014)
    Identifying pathogenic processes by integrating microarray data with prior knowledge
    BMC Bioinformatics, 15, 115
    DOI 10.1186/1471-2105-15-115, PubMed 24758699
  6. Nygaard V, Prasmickaite L, Vasiliauskaite K, Clancy T, Hovig E (2014)
    Melanoma brain colonization involves the emergence of a brain-adaptive phenotype
    Oncoscience, 1 (1), 82-94
    DOI 10.18632/oncoscience.11, PubMed 25593989
  7. Paulsen J, Rødland EA, Holden L, Holden M, Hovig E (2014)
    A statistical model of ChIA-PET data for accurate detection of chromatin 3D interactions
    Nucleic Acids Res, 42 (18), e143
    DOI 10.1093/nar/gku738, PubMed 25114054
  8. Paulsen J, Sandve GK, Gundersen S, Lien TG, Trengereid K, Hovig E (2014)
    HiBrowse: multi-purpose statistical analysis of genome-wide chromatin 3D organization
    Bioinformatics, 30 (11), 1620-2
    DOI 10.1093/bioinformatics/btu082, PubMed 24511080

Publications 2013

  1. Bettum IJ, Vasiliauskaite K, Nygaard V, Clancy T, Pettersen SJ, Tenstad E, Mælandsmo GM, Prasmickaite L (2013)
    Metastasis-associated protein S100A4 induces a network of inflammatory cytokines that activate stromal cells to acquire pro-tumorigenic properties
    Cancer Lett, 344 (1), 28-39
    DOI 10.1016/j.canlet.2013.10.036, PubMed 24215866
  2. Bøe SL, Hovig E (2013)
    Light-induced mRNA transfection
    Methods Mol Biol, 969, 89-100
    DOI 10.1007/978-1-62703-260-5_6, PubMed 23296929
  3. Bøe SL, Jørgensen JA, Longva AS, Lavelle T, Sæbøe-Larssen S, Hovig E (2013)
    Light-controlled modulation of gene expression using polyamidoamine formulations
    Nucleic Acid Ther, 23 (2), 160-5
    DOI 10.1089/nat.2012.0413, PubMed 23530684
  4. Clancy T, Rødland EA, Nygard S, Hovig E (2013)
    Predicting physical interactions between protein complexes
    Mol Cell Proteomics, 12 (6), 1723-34
    DOI 10.1074/mcp.O112.019828, PubMed 23438732
  5. Fromm B, Worren MM, Hahn C, Hovig E, Bachmann L (2013)
    Substantial loss of conserved and gain of novel MicroRNA families in flatworms
    Mol Biol Evol, 30 (12), 2619-28
    DOI 10.1093/molbev/mst155, PubMed 24025793
  6. Jørgensen JA, Longva AS, Hovig E, Bøe SL (2013)
    Evaluation of biodegradable peptide carriers for light-directed targeting
    Nucleic Acid Ther, 23 (2), 131-9
    DOI 10.1089/nat.2012.0403, PubMed 23405950
  7. Lando M, Wilting SM, Snipstad K, Clancy T, Bierkens M, Aarnes EK, Holden M, Stokke T, Sundfør K, Holm R, Kristensen GB, Steenbergen RD, Lyng H (2013)
    Identification of eight candidate target genes of the recurrent 3p12-p14 loss in cervical cancer by integrative genomic profiling
    J Pathol, 230 (1), 59-69
    DOI 10.1002/path.4168, PubMed 23335387
  8. Lorvik KB, Haabeth OA, Clancy T, Bogen B, Corthay A (2013)
    Molecular profiling of tumor-specific TH1 cells activated in vivo
    Oncoimmunology, 2 (5), e24383
    DOI 10.4161/onci.24383, PubMed 23762808
  9. Paulsen J, Lien TG, Sandve GK, Holden L, Borgan O, Glad IK, Hovig E (2013)
    Handling realistic assumptions in hypothesis testing of 3D co-localization of genomic elements
    Nucleic Acids Res, 41 (10), 5164-74
    DOI 10.1093/nar/gkt227, PubMed 23571755
  10. Sandve GK, Gundersen S, Johansen M, Glad IK, Gunathasan K, Holden L, Holden M, Liestøl K, Nygård S, Nygaard V, Paulsen J, Rydbeck H, Trengereid K, Clancy T, Drabløs F, Ferkingstad E, Kalas M, Lien T, Rye MB, Frigessi A, Hovig E (2013)
    The Genomic HyperBrowser: an analysis web server for genome-scale data
    Nucleic Acids Res, 41 (Web Server issue), W133-41
    DOI 10.1093/nar/gkt342, PubMed 23632163
  11. Sandve GK, Nekrutenko A, Taylor J, Hovig E (2013)
    Ten simple rules for reproducible computational research
    PLoS Comput Biol, 9 (10), e1003285
    DOI 10.1371/journal.pcbi.1003285, PubMed 24204232
  12. Schee K, Lorenz S, Worren MM, Günther CC, Holden M, Hovig E, Fodstad O, Meza-Zepeda LA, Flatmark K (2013)
    Deep Sequencing the MicroRNA Transcriptome in Colorectal Cancer
    PLoS One, 8 (6), e66165
    DOI 10.1371/journal.pone.0066165, PubMed 23824282
  13. Yri OE, Ekstrøm PO, Hilden V, Gaudernack G, Liestøl K, Smeland EB, Holte H (2013)
    Influence of polymorphisms in genes encoding immunoregulatory proteins and metabolizing enzymes on susceptibility and outcome in patients with diffuse large B-cell lymphoma treated with rituximab
    Leuk Lymphoma, 54 (10), 2205-14
    DOI 10.3109/10428194.2013.774392, PubMed 23391141

Publications 2012

  1. Ekstrøm PO, Warren DJ, Thilly WG (2012)
    Separation principles of cycling temperature capillary electrophoresis
    Electrophoresis, 33 (7), 1162-8
    DOI 10.1002/elps.201100550, PubMed 22539319
  2. Jørgensen JA, Hovig E, Bøe SL (2012)
    Potent gene silencing in vitro at physiological pH using chitosan polymers
    Nucleic Acid Ther, 22 (2), 96-102
    DOI 10.1089/nat.2011.0335, PubMed 22480314
  3. Kresse SH, Rydbeck H, Skårn M, Namløs HM, Barragan-Polania AH, Cleton-Jansen AM, Serra M, Liestøl K, Hogendoorn PC, Hovig E, Myklebost O, Meza-Zepeda LA (2012)
    Integrative analysis reveals relationships of genetic and epigenetic alterations in osteosarcoma
    PLoS One, 7 (11), e48262
    DOI 10.1371/journal.pone.0048262, PubMed 23144859
  4. Liu F, Kuo WP, Jenssen TK, Hovig E (2012)
    Performance comparison of multiple microarray platforms for gene expression profiling
    Methods Mol Biol, 802, 141-55
    DOI 10.1007/978-1-61779-400-1_10, PubMed 22130879
  5. Mattingsdal M, Brown AA, Djurovic S, Sønderby IE, Server A, Melle I, Agartz I, Hovig E, Jensen J, Andreassen OA (2012)
    Pathway analysis of genetic markers associated with a functional MRI faces paradigm implicates polymorphisms in calcium responsive pathways
    Neuroimage, 70, 143-9
    DOI 10.1016/j.neuroimage.2012.12.035, PubMed 23274185
  6. Nakken S, Johansen M, Fillebeen J, Berge OP, Kirkerød H, Jenssen TK, Hovig E (2012)
    CellLineMiner: a knowledge portal for human cell lines
    Bioinformation, 8 (22), 1119-22
    DOI 10.6026/97320630081119, PubMed 23251048
  7. Thingnes J, Lavelle TJ, Gjuvsland AB, Omholt SW, Hovig E (2012)
    Towards a quantitative understanding of the MITF-PIAS3-STAT3 connection
    BMC Syst Biol, 6, 11
    DOI 10.1186/1752-0509-6-11, PubMed 22316093
  8. Thingnes J, Lavelle TJ, Hovig E, Omholt SW (2012)
    Understanding the melanocyte distribution in human epidermis: an agent-based computational model approach
    PLoS One, 7 (7), e40377
    DOI 10.1371/journal.pone.0040377, PubMed 22792296
  9. Trachtenberg AJ, Robert JH, Abdalla AE, Fraser A, He SY, Lacy JN, Rivas-Morello C, Truong A, Hardiman G, Ohno-Machado L, Liu F, Hovig E, Kuo WP (2012)
    A primer on the current state of microarray technologies
    Methods Mol Biol, 802, 3-17
    DOI 10.1007/978-1-61779-400-1_1, PubMed 22130870
  10. Yri OE, Ekstrøm PO, Hilden V, Gaudernack G, Liestøl K, Smeland EB, Holte H (2012)
    Polymorphisms in genes encoding interleukin-10 and drug metabolizing enzymes GSTP1, GSTT1, GSTA1 and UGT1A1 influence risk and outcome in Hodgkin lymphoma
    Leuk Lymphoma, 53 (10), 1934-44
    DOI 10.3109/10428194.2012.682307, PubMed 22475179

Publications 2011

  1. Bruhn S, Barrenäs F, Mobini R, Andersson BA, Chavali S, Egan BS, Hovig E, Sandve GK, Langston MA, Rogers G, Wang H, Benson M (2011)
    Increased expression of IRF4 and ETS1 in CD4+ cells from patients with intermittent allergic rhinitis
    Allergy, 67 (1), 33-40
    DOI 10.1111/j.1398-9995.2011.02707.x, PubMed 21919915
  2. Bøe S, Prasmickaite L, Engesæter B, Hovig E (2011)
    Light-directed delivery of nucleic acids
    Methods Mol Biol, 764, 107-21
    DOI 10.1007/978-1-61779-188-8_7, PubMed 21748636
  3. Bøe SL, Longva AS, Hovig E (2011)
    A novel photosensitizer for light-controlled gene silencing
    Nucleic Acid Ther, 21 (5), 359-67
    DOI 10.1089/nat.2011.0309, PubMed 22004417
  4. Clancy T, Pedicini M, Castiglione F, Santoni D, Nygaard V, Lavelle TJ, Benson M, Hovig E (2011)
    Immunological network signatures of cancer progression and survival
    BMC Med Genomics, 4, 28
    DOI 10.1186/1755-8794-4-28, PubMed 21453479
  5. De Beule J, Hovig E, Benson M (2011)
    Introducing Dynamics into the Field of Biosemiotics A Formal Account with Examples from Language and Immunology
    Biosemiotics, 4 (1), 5-24
    DOI 10.1007/s12304-010-9101-1
  6. Gundersen S, Kalaš M, Abul O, Frigessi A, Hovig E, Sandve GK (2011)
    Identifying elemental genomic track types and representing them uniformly
    BMC Bioinformatics, 12, 494
    DOI 10.1186/1471-2105-12-494, PubMed 22208806
  7. Halle C, Lando M, Svendsrud DH, Clancy T, Holden M, Sundfør K, Kristensen GB, Holm R, Lyng H (2011)
    Membranous expression of ectodomain isoforms of the epidermal growth factor receptor predicts outcome after chemoradiotherapy of lymph node-negative cervical cancer
    Clin Cancer Res, 17 (16), 5501-12
    DOI 10.1158/1078-0432.CCR-11-0297, PubMed 21737508
  8. Hjortland GO, Meza-Zepeda LA, Beiske K, Ree AH, Tveito S, Hoifodt H, Bohler PJ, Hole KH, Myklebost O, Fodstad O, Smeland S, Hovig E (2011)
    Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma
    BMC Cancer, 11, 455
    DOI 10.1186/1471-2407-11-455, PubMed 22014070
  9. Sandve GK, Gundersen S, Rydbeck H, Glad IK, Holden L, Holden M, Liestøl K, Clancy T, Drabløs F, Ferkingstad E, Johansen M, Nygaard V, Tøstesen E, Frigessi A, Hovig E (2011)
    The differential disease regulome
    BMC Genomics, 12, 353
    DOI 10.1186/1471-2164-12-353, PubMed 21736759
  10. Selmer KK, Gilfillan GD, Strømme P, Lyle R, Hughes T, Hjorthaug HS, Brandal K, Nakken S, Misceo D, Egeland T, Munthe LA, Braekken SK, Undlien DE (2011)
    A mild form of Mucopolysaccharidosis IIIB diagnosed with targeted next-generation sequencing of linked genomic regions
    Eur J Hum Genet, 20 (1), 58-63
    DOI 10.1038/ejhg.2011.126, PubMed 21712855
  11. Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI (2011)
    CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer
    Genes Immun, 12 (8), 653-62
    DOI 10.1038/gene.2011.43, PubMed 21716316

Publications 2010

  1. Beck H, Nähse V, Larsen MS, Groth P, Clancy T, Lees M, Jørgensen M, Helleday T, Syljuåsen RG, Sørensen CS (2010)
    Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
    J Cell Biol, 188 (5), 629-38
    DOI 10.1083/jcb.200905059, PubMed 20194642
  2. Bøe S, Saebøe-Larssen S, Hovig E (2010)
    Light-induced gene expression using messenger RNA molecules
    Oligonucleotides, 20 (1), 1-6
    DOI 10.1089/oli.2009.0209, PubMed 20038251
  3. Bøe SL, Longva AS, Hovig E (2010)
    Cyclodextrin-containing polymer delivery system for light-directed siRNA gene silencing
    Oligonucleotides, 20 (4), 175-82
    DOI 10.1089/oli.2010.0230, PubMed 20645877
  4. Cekaite L, Clancy T, Sioud M (2010)
    Increased miR-21 expression during human monocyte differentiation into DCs
    Front Biosci (Elite Ed), 2 (3), 818-28
    DOI 10.2741/e143, PubMed 20515755
  5. Nakken S, Rødland EA, Hovig E (2010)
    Impact of DNA physical properties on local sequence bias of human mutation
    Hum Mutat, 31 (12), 1316-25
    DOI 10.1002/humu.21371, PubMed 20886615
  6. Pedicini M, Barrenäs F, Clancy T, Castiglione F, Hovig E, Kanduri K, Santoni D, Benson M (2010)
    Combining network modeling and gene expression microarray analysis to explore the dynamics of Th1 and Th2 cell regulation
    PLoS Comput Biol, 6 (12), e1001032
    DOI 10.1371/journal.pcbi.1001032, PubMed 21187905
  7. Sandve GK, Gundersen S, Rydbeck H, Glad IK, Holden L, Holden M, Liestøl K, Clancy T, Ferkingstad E, Johansen M, Nygaard V, Tøstesen E, Frigessi A, Hovig E (2010)
    The Genomic HyperBrowser: inferential genomics at the sequence level
    Genome Biol, 11 (12), R121
    DOI 10.1186/gb-2010-11-12-r121, PubMed 21182759
  8. Sioud M, Cekaite L (2010)
    Profiling of miRNA expression and prediction of target genes
    Methods Mol Biol, 629, 257-71
    DOI 10.1007/978-1-60761-657-3_16, PubMed 20387154

Publications 2009

  1. Cekaite L, Hovig E, Sioud M (2009)
    Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
    Methods Mol Biol, 524, 273-85
    DOI 10.1007/978-1-59745-450-6_20, PubMed 19377952
  2. Lehne G, Grasmo-Wendler UH, Berner JM, Meza-Zepeda LA, Adamsen BL, Flack A, Reiner A, Clausen OP, Hovig E, Myklebost O (2009)
    Upregulation of stem cell genes in multidrug resistant K562 leukemia cells
    Leuk Res, 33 (10), 1379-85
    DOI 10.1016/j.leukres.2009.03.028, PubMed 19394083
  3. Nakken S, Rognes T, Hovig E (2009)
    The disruptive positions in human G-quadruplex motifs are less polymorphic and more conserved than their neutral counterparts
    Nucleic Acids Res, 37 (17), 5749-56
    DOI 10.1093/nar/gkp590, PubMed 19617376
  4. Nakken S, Rødland EA, Rognes T, Hovig E (2009)
    Large-scale inference of the point mutational spectrum in human segmental duplications
    BMC Genomics, 10, 43
    DOI 10.1186/1471-2164-10-43, PubMed 19161616
  5. Nygaard V, Hovig E (2009)
    Methods for quantitation of gene expression
    Front Biosci (Landmark Ed), 14 (2), 552-69
    DOI 10.2741/3262, PubMed 19273085
  6. Thingnes J, Oyehaug L, Hovig E, Omholt SW (2009)
    The mathematics of tanning
    BMC Syst Biol, 3, 60
    DOI 10.1186/1752-0509-3-60, PubMed 19505344

Publications 2008

  1. Boe S, Longva AS, Hovig E (2008)
    Evaluation of various polyethylenimine formulations for light-controlled gene silencing using small interfering RNA molecules
    Oligonucleotides, 18 (2), 123-32
    DOI 10.1089/oli.2008.0131, PubMed 18637730
  2. Boye K, Grotterød I, Aasheim HC, Hovig E, Maelandsmo GM (2008)
    Activation of NF-kappaB by extracellular S100A4: analysis of signal transduction mechanisms and identification of target genes
    Int J Cancer, 123 (6), 1301-10
    DOI 10.1002/ijc.23617, PubMed 18548584
  3. Kraus I, Driesch C, Vinokurova S, Hovig E, Schneider A, von Knebel Doeberitz M, Dürst M (2008)
    The majority of viral-cellular fusion transcripts in cervical carcinomas cotranscribe cellular sequences of known or predicted genes
    Cancer Res, 68 (7), 2514-22
    DOI 10.1158/0008-5472.CAN-07-2776, PubMed 18381461
  4. Lyng H, Lando M, Brøvig RS, Svendsrud DH, Johansen M, Galteland E, Brustugun OT, Meza-Zepeda LA, Myklebost O, Kristensen GB, Hovig E, Stokke T (2008)
    GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data
    Genome Biol, 9 (5), R86
    DOI 10.1186/gb-2008-9-5-r86, PubMed 18500990
  5. Nygaard V, Hovig E (2008)
    Cell sampling and global nucleic acid amplification
    SEB Exp Biol Ser, 61, 17-36
    PubMed 18709735
  6. Nygaard V, Liu F, Holden M, Kuo WP, Trimarchi J, Ohno-Machado L, Cepko CL, Frigessi A, Glad IK, Wiel MA, Hovig E, Lyng H (2008)
    Validation of oligoarrays for quantitative exploration of the transcriptome
    BMC Genomics, 9, 258
    DOI 10.1186/1471-2164-9-258, PubMed 18513391
  7. Sioud M, Cekaite L (2008)
    Expression profiling of microRNAs in cancer cells: technical considerations
    Methods Mol Biol, 439, 179-90
    DOI 10.1007/978-1-59745-188-8_12, PubMed 18370103
  8. Tøstesen E (2008)
    A stitch in time: efficient computation of genomic DNA melting bubbles
    Algorithms Mol Biol, 3, 10
    DOI 10.1186/1748-7188-3-10, PubMed 18637171
  9. Tøstesen E, Sandve GK, Liu F, Hovig E (2008)
    Segmentation of DNA sequences into twostate regions and melting fork regions
    J Phys Condens Matter, 21 (3), 034109
    DOI 10.1088/0953-8984/21/3/034109, PubMed 21817254

Publications 2007

  1. Benson M, Steenhoff Hov DA, Clancy T, Hovig E, Rudemo M, Cardell LO (2007)
    Connectivity can be used to identify key genes in DNA microarray data: a study based on gene expression in nasal polyps before and after treatment with glucocorticoids
    Acta Otolaryngol, 127 (10), 1074-9
    DOI 10.1080/00016480701200277, PubMed 17851899
  2. Bøe S, Longva AS, Hovig E (2007)
    Photochemically induced gene silencing using small interfering RNA molecules in combination with lipid carriers
    Oligonucleotides, 17 (2), 166-73
    DOI 10.1089/oli.2007.0076, PubMed 17638521
  3. Cekaite L, Hovig E, Sioud M (2007)
    Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
    Methods Mol Biol, 360, 335-48
    DOI 10.1385/1-59745-165-7:335, PubMed 17172738
  4. Cekaite L, Peng Q, Reiner A, Shahzidi S, Tveito S, Furre IE, Hovig E (2007)
    Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate
    BMC Genomics, 8, 273
    DOI 10.1186/1471-2164-8-273, PubMed 17692132
  5. Liu F, Jenssen TK, Trimarchi J, Punzo C, Cepko CL, Ohno-Machado L, Hovig E, Kuo WP (2007)
    Comparison of hybridization-based and sequencing-based gene expression technologies on biological replicates
    BMC Genomics, 8, 153
    DOI 10.1186/1471-2164-8-153, PubMed 17555589
  6. Liu F, Tøstesen E, Sundet JK, Jenssen TK, Bock C, Jerstad GI, Thilly WG, Hovig E (2007)
    The human genomic melting map
    PLoS Comput Biol, 3 (5), e93
    DOI 10.1371/journal.pcbi.0030093, PubMed 17511513
  7. Møller P, Hagen AI, Apold J, Maehle L, Clark N, Fiane B, Løvslett K, Hovig E, Vabø A (2007)
    Genetic epidemiology of BRCA mutations--family history detects less than 50% of the mutation carriers
    Eur J Cancer, 43 (11), 1713-7
    DOI 10.1016/j.ejca.2007.04.023, PubMed 17574839
  8. Sioud M, Furset G, Cekaite L (2007)
    Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
    Biochem Biophys Res Commun, 361 (1), 122-6
    DOI 10.1016/j.bbrc.2007.06.177, PubMed 17658482

Publications 2006

  1. Berner JM, Muller CR, Holden M, Wang J, Hovig E, Myklebost O (2006)
    Sampling effects on gene expression data from a human tumour xenograft
    Scand. J. Lab. Anim. Sci., 33 (1), 17-30
  2. Bøe S, Hovig E (2006)
    Photochemically induced gene silencing using PNA-peptide conjugates
    Oligonucleotides, 16 (2), 145-57
    DOI 10.1089/oli.2006.16.145, PubMed 16764538
  3. Cekaite L, Furset G, Hovig E, Sioud M (2006)
    Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
    J Mol Biol, 365 (1), 90-108
    DOI 10.1016/j.jmb.2006.09.034, PubMed 17054988
  4. Kuo WP, Liu F, Trimarchi J, Punzo C, Lombardi M, Sarang J, Whipple ME, Maysuria M, Serikawa K, Lee SY, McCrann D, Kang J, Shearstone JR, Burke J, Park DJ, Wang X, Rector TL, Ricciardi-Castagnoli P, Perrin S, Choi S, Bumgarner R, Kim JH, Short GF, Freeman MW, Seed B et al. (2006)
    A sequence-oriented comparison of gene expression measurements across different hybridization-based technologies
    Nat Biotechnol, 24 (7), 832-40
    DOI 10.1038/nbt1217, PubMed 16823376
  5. Nygaard V, Hovig E (2006)
    Options available for profiling small samples: a review of sample amplification technology when combined with microarray profiling
    Nucleic Acids Res, 34 (3), 996-1014
    DOI 10.1093/nar/gkj499, PubMed 16473852
  6. Prasmickaite L, Cekaite L, Hellum M, Hovig E, Høgset A, Berg K (2006)
    Transcriptome changes in a colon adenocarcinoma cell line in response to photochemical treatment as used in photochemical internalisation (PCI)
    FEBS Lett, 580 (24), 5739-46
    DOI 10.1016/j.febslet.2006.09.028, PubMed 17007842
  7. Stormorken A, Heintz KM, Andresen PA, Hovig E, Møller P (2006)
    MUTYH Mutations Do Not Cause HNPCC or Late Onset Familial Colorectal Cancer
    Hered Cancer Clin Pract, 4 (2), 90-3
    DOI 10.1186/1897-4287-4-2-90, PubMed 20223013

Publications 2005

  1. Gulliksen A, Solli LA, Drese KS, Sörensen O, Karlsen F, Rogne H, Hovig E, Sirevåg R (2005)
    Parallel nanoliter detection of cancer markers using polymer microchips
    Lab Chip, 5 (4), 416-20
    DOI 10.1039/b415525d, PubMed 15791339
  2. Jenssen TK, Hovig E (2005)
    Gene-expression profiling in breast cancer
    Lancet, 365 (9460), 634-5
    DOI 10.1016/S0140-6736(05)17959-8, PubMed 15721457
  3. Lyng H, Landsverk KS, Kristiansen E, DeAngelis PM, Ree AH, Myklebost O, Hovig E, Stokke T (2005)
    Response of malignant B lymphocytes to ionizing radiation: gene expression and genotype
    Int J Cancer, 115 (6), 935-42
    DOI 10.1002/ijc.20962, PubMed 15723354
  4. Nygaard V, Holden M, Løland A, Langaas M, Myklebost O, Hovig E (2005)
    Limitations of mRNA amplification from small-size cell samples
    BMC Genomics, 6, 147
    DOI 10.1186/1471-2164-6-147, PubMed 16253144
  5. Tøstesen E (2005)
    Partly melted DNA conformations obtained with a probability peak finding method
    Phys Rev E Stat Nonlin Soft Matter Phys, 71 (6 Pt 1), 061922
    DOI 10.1103/PhysRevE.71.061922, PubMed 16089780
  6. Tøstesen E, Jerstad GI, Hovig E (2005) analysis of partly melted DNA conformations using stitch profiles
    Nucleic Acids Res, 33 (Web Server issue), W573-6
    DOI 10.1093/nar/gki424, PubMed 15980539

Publications 2004

  1. Bjørge T, Lie AK, Hovig E, Gislefoss RE, Hansen S, Jellum E, Langseth H, Nustad K, Tropé CG, Dørum A (2004)
    BRCA1 mutations in ovarian cancer and borderline tumours in Norway: a nested case-control study
    Br J Cancer, 91 (10), 1829-34
    DOI 10.1038/sj.bjc.6602199, PubMed 15477862
  2. Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
    Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
    Proteomics, 4 (9), 2572-82
    DOI 10.1002/pmic.200300768, PubMed 15352232
  3. Cekaite L, Hovig E, Hauge HH (2004)
    Double-sided silicon strip detectors: new applications within genomics and proteomics
    Nucl. Instrum. Methods Phys. Res. Sect. A-Accel. Spectrom. Dect. Assoc. Equip., 527 (1-2), 68-72
    DOI 10.1016/j.nima.2004.03.063
  4. Cruciani V, Heintz KM, Husøy T, Hovig E, Warren DJ, Mikalsen SO (2004)
    The detection of hamster connexins: a comparison of expression profiles with wild-type mouse and the cancer-prone Min mouse
    Cell Commun Adhes, 11 (5-6), 155-71
    DOI 10.1080/15419060500242877, PubMed 16194882
  5. Ekstrøm PO, Bjørge T, Dørum A, Longva AS, Heintz KM, Warren DJ, Hansen S, Gislefoss RE, Hovig E (2004)
    Determination of hereditary mutations in the BRCA1 gene using archived serum samples and capillary electrophoresis
    Anal Chem, 76 (15), 4406-9
    DOI 10.1021/ac049788k, PubMed 15283579
  6. Gulliksen A, Solli L, Karlsen F, Rogne H, Hovig E, Nordstrøm T, Sirevåg R (2004)
    Real-time nucleic acid sequence-based amplification in nanoliter volumes
    Anal Chem, 76 (1), 9-14
    DOI 10.1021/ac034779h, PubMed 14697026
  7. Kuo WP, Kim EY, Trimarchi J, Jenssen TK, Vinterbo SA, Ohno-Machado L (2004)
    A primer on gene expression and microarrays for machine learning researchers
    J Biomed Inform, 37 (4), 293-303
    DOI 10.1016/j.jbi.2004.07.002, PubMed 15465482
  8. Kuo WP, Whipple ME, Epstein JB, Jenssen TK, Santos GS, Ohno-Machado L, Sonis ST (2004)
    Deciphering gene expression profiles generated from DNA microarrays and their applications in oral medicine
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 97 (5), 584-91
    DOI 10.1016/j.tripleo.2003.11.016, PubMed 15153870
  9. Liu F, Jenssen TK, Nygaard V, Sack J, Hovig E (2004)
    FigSearch: a figure legend indexing and classification system
    Bioinformatics, 20 (16), 2880-2
    DOI 10.1093/bioinformatics/bth316, PubMed 15145804
  10. Liu F, Jenssen TK, Nygaard V, Sack J, Hovig E (2004)
    FigSearch: Using maximum entropy classifier to categorize biological figures
  11. Lyng H, Badiee A, Svendsrud DH, Hovig E, Myklebost O, Stokke T (2004)
    Profound influence of microarray scanner characteristics on gene expression ratios: analysis and procedure for correction
    BMC Genomics, 5 (1), 10
    DOI 10.1186/1471-2164-5-10, PubMed 15018648
  12. Trøen G, Nygaard V, Jenssen TK, Ikonomou IM, Tierens A, Matutes E, Gruszka-Westwood A, Catovsky D, Myklebost O, Lauritzsen G, Hovig E, Delabie J (2004)
    Constitutive expression of the AP-1 transcription factors c-jun, junD, junB, and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma
    J Mol Diagn, 6 (4), 297-307
    DOI 10.1016/S1525-1578(10)60525-9, PubMed 15507668
  13. Wang X, Wang M, Amarzguioui M, Liu F, Fodstad Ø, Prydz H (2004)
    Downregulation of tissue factor by RNA interference in human melanoma LOX-L cells reduces pulmonary metastasis in nude mice
    Int J Cancer, 112 (6), 994-1002
    DOI 10.1002/ijc.20527, PubMed 15386437

Publications 2003

  1. Andersen K, Smith-Sørensen B, Pedersen KB, Hovig E, Myklebost O, Fodstad Ø, Maelandsmo GM (2003)
    Interferon-gamma suppresses S100A4 transcription independently of apoptosis or cell cycle arrest
    Br J Cancer, 88 (12), 1995-2001
    DOI 10.1038/sj.bjc.6600998, PubMed 12799648
  2. Haslekås C, Grini PE, Nordgard SH, Thorstensen T, Viken MK, Nygaard V, Aalen RB (2003)
    ABI3 mediates expression of the peroxiredoxin antioxidant AtPER1 gene and induction by oxidative stress
    Plant Mol Biol, 53 (3), 313-26
    DOI 10.1023/b:plan.0000006937.21343.2a, PubMed 14750521
  3. Haslekås C, Viken MK, Grini PE, Nygaard V, Nordgard SH, Meza TJ, Aalen RB (2003)
    Seed 1-cysteine peroxiredoxin antioxidants are not involved in dormancy, but contribute to inhibition of germination during stress
    Plant Physiol, 133 (3), 1148-57
    DOI 10.1104/pp.103.025916, PubMed 14526116
  4. Kuo WP, Whipple ME, Jenssen TK, Todd R, Epstein JB, Ohno-Machado L, Sonis ST, Park PJ (2003)
    Microarrays and clinical dentistry
    J Am Dent Assoc, 134 (4), 456-62
    DOI 10.14219/jada.archive.2003.0195, PubMed 12733779
  5. Mathisen B, Lindstad RI, Hansen J, El-Gewely SA, Maelandsmo GM, Hovig E, Fodstad O, Loennechen T, Winberg JO (2003)
    S100A4 regulates membrane induced activation of matrix metalloproteinase-2 in osteosarcoma cells
    Clin Exp Metastasis, 20 (8), 701-11
    DOI 10.1023/b:clin.0000006819.21361.03, PubMed 14713104
  6. Nygaard V, Løland A, Holden M, Langaas M, Rue H, Liu F, Myklebost O, Fodstad Ø, Hovig E, Smith-Sørensen B (2003)
    Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance
    BMC Genomics, 4 (1), 11
    DOI 10.1186/1471-2164-4-11, PubMed 12659661
  7. Tøstesen E, Liu F, Jenssen TK, Hovig E (2003)
    Speed-up of DNA melting algorithm with complete nearest neighbor properties
    Biopolymers, 70 (3), 364-76
    DOI 10.1002/bip.10495, PubMed 14579309
  8. Wang J, Bø TH, Jonassen I, Myklebost O, Hovig E (2003)
    Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data
    BMC Bioinformatics, 4, 60
    DOI 10.1186/1471-2105-4-60, PubMed 14651757
  9. Wang J, Myklebost O, Hovig E (2003)
    MGraph: graphical models for microarray data analysis
    Bioinformatics, 19 (17), 2210-1
    DOI 10.1093/bioinformatics/btg298, PubMed 14630649

Publications 2002

  1. Jenssen TK, Hovig E (2002)
    The semantic web and biology
    Drug Discov Today, 7 (19), 992
    DOI 10.1016/s1359-6446(02)02458-3, PubMed 12546914
  2. Jenssen TK, Kuo WP, Stokke T, Hovig E (2002)
    Associations between gene expressions in breast cancer and patient survival
    Hum Genet, 111 (4-5), 411-20
    DOI 10.1007/s00439-002-0804-5, PubMed 12384785
  3. Jenssen TK, Langaas M, Kuo WP, Smith-Sørensen B, Myklebost O, Hovig E (2002)
    Analysis of repeatability in spotted cDNA microarrays
    Nucleic Acids Res, 30 (14), 3235-44
    DOI 10.1093/nar/gkf441, PubMed 12136105
  4. Kuo WP, Jenssen TK, Butte AJ, Ohno-Machado L, Kohane IS (2002)
    Analysis of matched mRNA measurements from two different microarray technologies
    Bioinformatics, 18 (3), 405-12
    DOI 10.1093/bioinformatics/18.3.405, PubMed 11934739
  5. Kuo WP, Jenssen TK, Park PJ, Lingen MW, Hasina R, Ohno-Machado L (2002)
    Gene expression levels in different stages of progression in oral squamous cell carcinoma
    Proc AMIA Symp, 415-9
    PubMed 12474876
  6. Kuo WP, Whipple ME, Sonis ST, Ohno-Machado L, Jenssen TK (2002)
    Gene expression profiling by DNA microarrays and its application to dental research
    Oral Oncol, 38 (7), 650-6
    DOI 10.1016/s1368-8375(02)00013-1, PubMed 12353490
  7. Ohno-Machado L, Vinterbo S, Dreiseitl S, Jenssen TK, Kuo W (2002)
    Comparing imperfect measurements with the Bland-Altman technique: application in gene expression analysis
    Proc AMIA Symp, 572-6
    PubMed 12463888
  8. Ree AH, Engebraaten O, Hovig E, Fodstad Ø (2002)
    Differential display analysis of breast carcinoma cells enriched by immunomagnetic target cell selection: gene expression profiles in bone marrow target cells
    Int J Cancer, 97 (1), 28-33
    DOI 10.1002/ijc.1564, PubMed 11774240
  9. Smith-Sørensen B, Lind GE, Skotheim RI, Fosså SD, Fodstad Ø, Stenwig AE, Jakobsen KS, Lothe RA (2002)
    Frequent promoter hypermethylation of the O6-Methylguanine-DNA Methyltransferase (MGMT) gene in testicular cancer
    Oncogene, 21 (57), 8878-84
    DOI 10.1038/sj.onc.1205978, PubMed 12483540
  10. Wang J, Nygaard V, Smith-Sørensen B, Hovig E, Myklebost O (2002)
    MArray: analysing single, replicated or reversed microarray experiments
    Bioinformatics, 18 (8), 1139-40
    DOI 10.1093/bioinformatics/18.8.1139, PubMed 12176840

Publications 2001

  1. Børresen-Dale AL, Hovig E, Smith-Sørensen B (2001)
    Detection of mutations by denaturing gradient gel electrophoresis
    Curr Protoc Hum Genet, Chapter 7, Unit 7.5
    DOI 10.1002/0471142905.hg0705s17, PubMed 18428306
  2. Hovig E, Maelandsmo G, Mellingsaeter T, Fodstad O, Mielewczyk SS, Wolfe J, Goodchild J (2001)
    Optimization of hammerhead ribozymes for the cleavage of S100A4 (CAPL) mRNA
    Antisense Nucleic Acid Drug Dev, 11 (2), 67-75
    DOI 10.1089/108729001750171272, PubMed 11334142
  3. Hovig E, Rye PD, Warren DJ, Nustad K (2001)
    CA 125: the end of the beginning
    Tumour Biol, 22 (6), 345-7
    DOI 10.1159/000050637, PubMed 11786728
  4. Jenssen TK, Laegreid A, Komorowski J, Hovig E (2001)
    A literature network of human genes for high-throughput analysis of gene expression
    Nat Genet, 28 (1), 21-8
    DOI 10.1038/ng0501-21, PubMed 11326270
  5. Komorowski J, Hvidsten TR, Jenssen TK, Tjeldvoll D, Hovig E, Laegreid A, Sandvik AK (2001)
    [New knowledge derived from measurement of gene expression with the DNA microarray method]
    Tidsskr Nor Laegeforen, 121 (10), 1229-32
    PubMed 11402750
  6. Lothe RA, Smith-Sørensen B, Hektoen M, Stenwig AE, Mandahl N, Saeter G, Mertens F (2001)
    Biallelic inactivation of TP53 rarely contributes to the development of malignant peripheral nerve sheath tumors
    Genes Chromosomes Cancer, 30 (2), 202-6
    DOI 10.1002/1098-2264(2000)9999:9999<::AID-GCC1079>3.0.CO;2-5, PubMed 11135438
  7. Møller P, Borg A, Heimdal K, Apold J, Vallon-Christersson J, Hovig E, Maehle L, Norwegian Inherited Breast Cancer Group, Norwegian Inherited Ovarian Cancer Group (2001)
    The BRCA1 syndrome and other inherited breast or breast-ovarian cancers in a Norwegian prospective series
    Eur J Cancer, 37 (8), 1027-32
    DOI 10.1016/s0959-8049(01)00075-2, PubMed 11334729
  8. Møller P, Heimdal K, Apold J, Fredriksen A, Borg A, Hovig E, Hagen A, Hagen B, Pedersen JC, Maehle L, Norwegian Inherited Breast Cancer Group, Norwegian Inherited Ovarian Cancer Group (2001)
    Genetic epidemiology of BRCA1 mutations in Norway
    Eur J Cancer, 37 (18), 2428-34
    DOI 10.1016/s0959-8049(01)00299-4, PubMed 11720839
  9. Warren W, Hovig E, Smith-Sørensen B, Børresen AL, Fujimura FK, Liu Q, Feng J, Sommer SS (2001)
    Detection of mutations by single-strand conformation polymorphism (SSCP) analysis and SSCP-hybrid methods
    Curr Protoc Hum Genet, Chapter 7, Unit 7.4
    DOI 10.1002/0471142905.hg0704s15, PubMed 18428305

Publications 2000

  1. Komorowski J, Hvidsten TR, Jenssen TK, Tjeldvoll D, Hovig E, Sandvik AK, Laegreid A (2000)
    Towards Knowledge Discovery from cDNA Microarray Gene Expression Data
    Lect. Notes Comput. Sci., 1910, 470-475

Publications 1999

  1. Bjørnland K, Winberg JO, Odegaard OT, Hovig E, Loennechen T, Aasen AO, Fodstad O, Maelandsmo GM (1999)
    S100A4 involvement in metastasis: deregulation of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in osteosarcoma cells transfected with an anti-S100A4 ribozyme
    Cancer Res, 59 (18), 4702-8
    PubMed 10493528
  2. Borg A, Dørum A, Heimdal K, Maehle L, Hovig E, Møller P (1999)
    BRCA1 1675delA and 1135insA account for one third of Norwegian familial breast-ovarian cancer and are associated with later disease onset than less frequent mutations
    Dis Markers, 15 (1-3), 79-84
    DOI 10.1155/1999/278269, PubMed 10595257
  3. Danielsen T, Smith-Sørensen B, Grønlund HA, Hvidsten M, Børresen-Dale AL, Rofstad EK (1999)
    No association between radiosensitivity and TP53 status, G1 arrest or protein levels of p53, myc, ras or raf in human melanoma lines
    Int J Radiat Biol, 75 (9), 1149-60
    DOI 10.1080/095530099139629, PubMed 10528923
  4. Dørum A, Heimdal K, Hovig E, Inganäs M, Møller P (1999)
    Penetrances of BRCA1 1675delA and 1135insA with respect to breast cancer and ovarian cancer
    Am J Hum Genet, 65 (3), 671-9
    DOI 10.1086/302530, PubMed 10441573
  5. Dørum A, Hovig E, Tropé C, Inganas M, Møller P (1999)
    Three per cent of Norwegian ovarian cancers are caused by BRCA1 1675delA or 1135insA
    Eur J Cancer, 35 (5), 779-81
    DOI 10.1016/s0959-8049(99)00050-7, PubMed 10505039
  6. Lonning PE, Johnsen H, Geisler S, Aas T, Smith-Sorensen B, Akslen LA, Borresen-Dale AL (1999)
    TP53 as a predictor of response to chemotherapy in breast cancer
    ESO SCI UPDATES, 4, 73-88
  7. Ree AH, Tvermyr M, Engebraaten O, Rooman M, Røsok O, Hovig E, Meza-Zepeda LA, Bruland OS, Fodstad O (1999)
    Expression of a novel factor in human breast cancer cells with metastatic potential
    Cancer Res, 59 (18), 4675-80
    PubMed 10493524
  8. Ruud P, Fodstad O, Hovig E (1999)
    Identification of a novel cytokeratin 19 pseudogene that may interfere with reverse transcriptase-polymerase chain reaction assays used to detect micrometastatic tumor cells
    Int J Cancer, 80 (1), 119-25
    DOI 10.1002/(sici)1097-0215(19990105)80:1<119::aid-ijc22>;2-x, PubMed 9935241
  9. Wacey AI, Cooper DN, Liney D, Hovig E, Krawczak M (1999)
    Disentangling the perturbational effects of amino acid substitutions in the DNA-binding domain of p53
    Hum Genet, 104 (1), 15-22
    DOI 10.1007/s004390050904, PubMed 10071187

Publications 1998

  1. Andersen K, Maelandsmo GM, Hovig E, Fodstad O, Loennechen T, Winberg JO (1998)
    Interleukin-1 alpha and basic fibroblast growth factor induction of matrix metalloproteinases and their inhibitors in osteosarcoma cells is modulated by the metastasis associated protein CAPL
    Anticancer Res, 18 (5A), 3299-303
    PubMed 9858899
  2. Prasmickaite L, Hogset A, Maelandsmo G, Berg K, Goodchild J, Perkins T, Fodstad O, Hovig E (1998)
    Intracellular metabolism of a 2'-O-methyl-stabilized ribozyme after uptake by DOTAP transfection or asfree ribozyme. A study by capillary electrophoresis
    Nucleic Acids Res, 26 (18), 4241-8
    DOI 10.1093/nar/26.18.4241, PubMed 9722645

Publications 1997

  1. de Graaf H, Maelandsmo GM, Ruud P, Forus A, Oyjord T, Fodstad O, Hovig E (1997)
    Ectopic expression of target genes may represent an inherent limitation of RT-PCR assays used for micrometastasis detection: studies on the epithelial glycoprotein gene EGP-2
    Int J Cancer, 72 (1), 191-6
    DOI 10.1002/(sici)1097-0215(19970703)72:1<191::aid-ijc27>;2-l, PubMed 9212242
  2. Dørum A, Møller P, Kamsteeg EJ, Scheffer H, Burton M, Heimdal KR, Maehle LO, Hovig E, Tropé CG, van der Hout AH, van der Meulen MA, Buys CH, te Meerman GJ (1997)
    A BRCA1 founder mutation, identified with haplotype analysis, allowing genotype/phenotype determination and predictive testing
    Eur J Cancer, 33 (14), 2390-2
    DOI 10.1016/s0959-8049(97)00328-6, PubMed 9616287
  3. Hainaut P, Soussi T, Shomer B, Hollstein M, Greenblatt M, Hovig E, Harris CC, Montesano R (1997)
    Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects
    Nucleic Acids Res, 25 (1), 151-7
    DOI 10.1093/nar/25.1.151, PubMed 9016527
  4. Maelandsmo GM, Flørenes VA, Mellingsaeter T, Hovig E, Kerbel RS, Fodstad O (1997)
    Differential expression patterns of S100A2, S100A4 and S100A6 during progression of human malignant melanoma
    Int J Cancer, 74 (4), 464-9
    DOI 10.1002/(sici)1097-0215(19970822)74:4<464::aid-ijc19>;2-9, PubMed 9291441

Publications 1996

  1. Hollstein M, Shomer B, Greenblatt M, Soussi T, Hovig E, Montesano R, Harris CC (1996)
    Somatic point mutations in the p53 gene of human tumors and cell lines: updated compilation
    Nucleic Acids Res, 24 (1), 141-6
    DOI 10.1093/nar/24.1.141, PubMed 8594564
  2. Hovig E, Fodstad O (1996)
    [Prostate-specific membrane antigen]
    Tidsskr Nor Laegeforen, 116 (3), 411-2
    PubMed 8638273
  3. Maelandsmo GM, Flørenes VA, Hovig E, Oyjord T, Engebraaten O, Holm R, Børresen AL, Fodstad O (1996)
    Involvement of the pRb/p16/cdk4/cyclin D1 pathway in the tumorigenesis of sporadic malignant melanomas
    Br J Cancer, 73 (8), 909-16
    DOI 10.1038/bjc.1996.181, PubMed 8611425
  4. Maelandsmo GM, Hovig E, Skrede M, Engebraaten O, Flørenes VA, Myklebost O, Grigorian M, Lukanidin E, Scanlon KJ, Fodstad O (1996)
    Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts1) ribozyme
    Cancer Res, 56 (23), 5490-8
    PubMed 8968106
  5. Smith-Sørensen B, Hovig E (1996)
    CDKN2A (p16INK4A) somatic and germline mutations
    Hum Mutat, 7 (4), 294-303
    DOI 10.1002/(SICI)1098-1004(1996)7:4<294::AID-HUMU2>3.0.CO;2-9, PubMed 8723678
  6. Aas T, Børresen AL, Geisler S, Smith-Sørensen B, Johnsen H, Varhaug JE, Akslen LA, Lønning PE (1996)
    Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients
    Nat Med, 2 (7), 811-4
    DOI 10.1038/nm0796-811, PubMed 8673929

Publications 1995

  1. Deggerdal AH, Pettersen F, Kvalheim G, Hornes E, Smeland E, Fodstad O, Hovig E (1995)
    Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
    Lab Invest, 72 (4), 411-8
    PubMed 7723279
  2. Krawczak M, Smith-Sorensen B, Schmidtke J, Kakkar VV, Cooper DN, Hovig E (1995)
    Somatic spectrum of cancer-associated single basepair substitutions in the TP53 gene is determined mainly by endogenous mechanisms of mutation and by selection
    Hum Mutat, 5 (1), 48-57
    DOI 10.1002/humu.1380050107, PubMed 7728149
  3. Maelandsmo GM, Berner JM, Flørenes VA, Forus A, Hovig E, Fodstad O, Myklebost O (1995)
    Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas--relationship to amplification and mRNA levels of CDK4 and CCND1
    Br J Cancer, 72 (2), 393-8
    DOI 10.1038/bjc.1995.344, PubMed 7640224

Publications 1994

  1. Hollstein M, Rice K, Greenblatt MS, Soussi T, Fuchs R, Sørlie T, Hovig E, Smith-Sørensen B, Montesano R, Harris CC (1994)
    Database of p53 gene somatic mutations in human tumors and cell lines
    Nucleic Acids Res, 22 (17), 3551-5
    PubMed 7937055
  2. McIntyre JF, Smith-Sorensen B, Friend SH, Kassell J, Borresen AL, Yan YX, Russo C, Sato J, Barbier N, Miser J (1994)
    Germline mutations of the p53 tumor suppressor gene in children with osteosarcoma
    J Clin Oncol, 12 (5), 925-30
    DOI 10.1200/JCO.1994.12.5.925, PubMed 8164043

Publications 1993

  1. Andreassen A, Oyjord T, Hovig E, Holm R, Flørenes VA, Nesland JM, Myklebost O, Høie J, Bruland OS, Børresen AL (1993)
    p53 abnormalities in different subtypes of human sarcomas
    Cancer Res, 53 (3), 468-71
    PubMed 8425179

Publications 1992

  1. Børresen AL, Andersen TI, Garber J, Barbier-Piraux N, Thorlacius S, Eyfjörd J, Ottestad L, Smith-Sørensen B, Hovig E, Malkin D (1992)
    Screening for germ line TP53 mutations in breast cancer patients
    Cancer Res, 52 (11), 3234-6
    PubMed 1591732
  2. Hovig E, Smith-Sørensen B, Gebhardt MC, Ryberg D, Lothe R, Børresen AL (1992)
    No alterations in exon 21 of the RB1 gene in sarcomas and carcinomas of the breast, colon, and lung
    Genes Chromosomes Cancer, 5 (2), 97-103
    DOI 10.1002/gcc.2870050202, PubMed 1381957
  3. Hovig E, Smith-Sørensen B, Uitterlinden AG, Børresen AL (1992)
    Detection of DNA variation in cancer
    Pharmacogenetics, 2 (6), 317-28
    DOI 10.1097/00008571-199212000-00011, PubMed 1306133
  4. Smith-Sørensen B, Hovig E, Andersson B, Børresen AL (1992)
    Screening for mutations in human HPRT cDNA using the polymerase chain reaction (PCR) in combination with constant denaturant gel electrophoresis (CDGE)
    Mutat Res, 269 (1), 41-53
    DOI 10.1016/0027-5107(92)90159-y, PubMed 1381470

Publications 1991

  1. Alfsen GC, Beiske K, Holte H, Hovig E, Deggerdal A, Sandlie I, Widing E, Slørdahl S, Klepper LK, Sizoo W (1991)
    T-cell receptor tau delta +/CD3+4-8-T- cell acute lymphoblastic leukemias: a distinct subgroup of leukemias in children. A report of five cases
    Blood, 77 (9), 2023-30
    PubMed 1826854
  2. Børresen AL, Hovig E, Smith-Sørensen B, Malkin D, Lystad S, Andersen TI, Nesland JM, Isselbacher KJ, Friend SH (1991)
    Constant denaturant gel electrophoresis as a rapid screening technique for p53 mutations
    Proc Natl Acad Sci U S A, 88 (19), 8405-9
    DOI 10.1073/pnas.88.19.8405, PubMed 1924299
  3. Hovig, Eivind, Smith-Sørensen B, Brøgger A, Børrensen AL (1991)
    Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
    Mutat Res, 263 (1), 61
    DOI 10.1016/0165-7992(91)90036-4, PubMed 2034242
  4. Hovig E, Smith-Sørensen B, Brøgger A, Børresen AL (1991)
    Constant denaturant gel electrophoresis, a modification of denaturing gradient gel electrophoresis, in mutation detection
    Mutat Res, 262 (1), 63-71
    DOI 10.1016/0165-7992(91)90108-g, PubMed 1702518

Publications 1990

    Prog.Clin.Biol.Res., 340, 389-398
  2. Børresen AL, Hovig E, Smith-Sørensen B, Vrieling H, Apold J, Brøgger A (1990)
    Screening for base mutations in the PAH and HPRT loci using the polymerase chain reaction (PCR) in combination with denaturing gradient gel electrophoresis (DGGE)
    Prog Clin Biol Res, 340A, 389-98
    PubMed 2388921

Publications 1989

  1. Olsnes S, Stenmark H, McGill S, Hovig E, Collier RJ, Sandvig K (1989)
    Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
    J Biol Chem, 264 (22), 12747-51
    PubMed 2753882
    J. Biol. Chem., 264 (22), 12749-12751

Publications 1988

  1. Børresen AL, Hovig E, Brøgger A (1988)
    Detection of base mutations in genomic DNA using denaturing gradient gel electrophoresis (DGGE) followed by transfer and hybridization with gene-specific probes
    Mutat Res, 202 (1), 77-83
    DOI 10.1016/0027-5107(88)90166-2, PubMed 2903443

Publications 1987

  1. Hovig E, Winberg JO, Fodstad O, Brøgger A, Gedde-Dahl T (1987)
    Chromosome 13 instability and esterase D expression in an osteosarcoma cell line
    Cancer Genet Cytogenet, 24 (2), 327-34
    DOI 10.1016/0165-4608(87)90115-4, PubMed 2878716
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