Nina Marie Pedersen

  • Postdoc (the Norwegian Cancer Society)
  • +47 22 78 18 19
 

Publications 2019

Sneeggen M, Pedersen NM, Campsteijn C, Haugsten EM, Stenmark H, Schink KO (2019)
WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
Nat. Commun., 10, 2850

Publications 2018

Wenzel EM, Schultz SW, Schink KO, Pedersen NM, Nahse V, Carlson A, Brech A, Stenmark H, Raiborg C (2018)
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
Nat. Commun., 9, 2932

Publications 2017

Hong Z, Pedersen NM, Wang L, Torgersen ML, Stenmark H, Raiborg C (2017)
PtdIns3P controls mTORC1 signaling through lysosomal positioning
J. Cell Biol., 216 (12), 4217-4233

Thorvaldsen TE, Pedersen NM, Wenzel EM, Stenmark H (2017)
Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and beta-Catenin Degradation
PLoS One, 12 (1), e0170508

Publications 2016

Pedersen NM, Thorvaldsen TE, Schultz SW, Wenzel EM, Stenmark H (2016)
Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity
PLoS One, 11 (8), e0160507

Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
ER-endosome contact sites in endosome positioning and protrusion outgrowth
Biochem. Soc. Trans., 44, 441-446

Raiborg C, Wenzel EM, Pedersen NM, Stenmark H (2016)
Phosphoinositides in membrane contact sites
Biochem. Soc. Trans., 44, 425-430

Publications 2015

Raiborg C, Wenzel EM, Pedersen NM, Olsvik H, Schink KO, Schultz SW, Vietri M, Nisi V, Bucci C, Brech A, Johansen T, Stenmark H (2015)
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth
Nature, 520 (7546), 234-+

Thorvaldsen TE, Pedersen NM, Wenzel EM, Schultz SW, Brech A, Liestol K, Waaler J, Krauss S, Stenmark H (2015)
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
Mol. Cancer Res., 13 (11), 1487-1501

Publications 2014

Kostaras E, Pedersen NM, Stenmark H, Fotsis T, Murphy C (2014)
SARA and RNF11 at the crossroads of EGFR signaling and trafficking
Methods Enzymol, 535, 225-47
DOI 10.1016/B978-0-12-397925-4.00014-6, PubMed 24377927

Publications 2012

Kostaras E, Sflomos G, Pedersen NM, Stenmark H, Fotsis T, Murphy C (2012)
SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking
Oncogene, 32 (44), 5220-32
DOI 10.1038/onc.2012.554, PubMed 23222715

Oksvold MP, Pedersen NM, Forfang L, Smeland EB (2012)
Effect of cycloheximide on epidermal growth factor receptor trafficking and signaling
FEBS Lett, 586 (20), 3575-81
DOI 10.1016/j.febslet.2012.08.022, PubMed 22971756

Oppelt A, Lobert VH, Haglund K, Mackey AM, Rameh LE, Liestøl K, Schink KO, Pedersen NM, Wenzel EM, Haugsten EM, Brech A, Rusten TE, Stenmark H, Wesche J (2012)
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
EMBO Rep, 14 (1), 57-64
DOI 10.1038/embor.2012.183, PubMed 23154468

Pedersen NM, Raiborg C, Brech A, Skarpen E, Roxrud I, Platta HW, Liestøl K, Stenmark H (2012)
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
Traffic, 13 (11), 1547-63
DOI 10.1111/j.1600-0854.2012.01400.x, PubMed 22816767

Sak MM, Breen K, Rønning SB, Pedersen NM, Bertelsen V, Stang E, Madshus IH (2012)
The oncoprotein ErbB3 is endocytosed in the absence of added ligand in a clathrin-dependent manner
Carcinogenesis, 33 (5), 1031-9
DOI 10.1093/carcin/bgs128, PubMed 22436610

Waaler J, Machon O, Tumova L, Dinh H, Korinek V, Wilson SR, Paulsen JE, Pedersen NM, Eide TJ, Machonova O, Gradl D, Voronkov A, von Kries JP, Krauss S (2012)
A novel tankyrase inhibitor decreases canonical Wnt signaling in colon carcinoma cells and reduces tumor growth in conditional APC mutant mice
Cancer Res, 72 (11), 2822-32
DOI 10.1158/0008-5472.CAN-11-3336, PubMed 22440753

Publications 2011

Malerød L, Pedersen NM, Sem Wegner CE, Lobert VH, Leithe E, Brech A, Rivedal E, Liestøl K, Stenmark H (2011)
Cargo-dependent degradation of ESCRT-I as a feedback mechanism to modulate endosomal sorting
Traffic, 12 (9), 1211-26
DOI 10.1111/j.1600-0854.2011.01220.x, PubMed 21564451

Rønning SB, Pedersen NM, Madshus IH, Stang E (2011)
CIN85 regulates ubiquitination and degradative endosomal sorting of the EGF receptor
Exp Cell Res, 317 (13), 1804-16
DOI 10.1016/j.yexcr.2011.05.016, PubMed 21635887

Publications 2010

Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H (2010)
Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes
Dev Cell, 19 (1), 148-59
DOI 10.1016/j.devcel.2010.06.010, PubMed 20643357

Sagona AP, Nezis IP, Pedersen NM, Liestøl K, Poulton J, Rusten TE, Skotheim RI, Raiborg C, Stenmark H (2010)
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
DOI 10.1038/ncb2036, PubMed 20208530

Thoresen SB, Pedersen NM, Liestøl K, Stenmark H (2010)
A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic
Exp Cell Res, 316 (20), 3368-78
DOI 10.1016/j.yexcr.2010.07.008, PubMed 20643123

Publications 2009

Pedersen NM, Breen K, Rødland MS, Haslekås C, Stang E, Madshus IH (2009)
Expression of epidermal growth factor receptor or ErbB3 facilitates geldanamycin-induced down-regulation of ErbB2
Mol Cancer Res, 7 (2), 275-84
DOI 10.1158/1541-7786.MCR-07-2183, PubMed 19208749

Wegner CS, Malerød L, Pedersen NM, Progida C, Bakke O, Stenmark H, Brech A (2009)
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
DOI 10.1007/s00418-009-0643-8, PubMed 19830447

Publications 2008

Pedersen NM, Madshus IH, Haslekås C, Stang E (2008)
Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent
Mol Cancer Res, 6 (3), 491-500
DOI 10.1158/1541-7786.MCR-07-0191, PubMed 18337455

Roxrud I, Raiborg C, Pedersen NM, Stang E, Stenmark H (2008)
An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor
J Cell Biol, 180 (6), 1205-18
DOI 10.1083/jcb.200708115, PubMed 18362181

Publications 2007

Raiborg C, Malerød L, Pedersen NM, Stenmark H (2007)
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
DOI 10.1016/j.yexcr.2007.10.014, PubMed 18031739

Publications 2006

Johannessen LE, Pedersen NM, Pedersen KW, Madshus IH, Stang E (2006)
Activation of the epidermal growth factor (EGF) receptor induces formation of EGF receptor- and Grb2-containing clathrin-coated pits
Mol Cell Biol, 26 (2), 389-401
DOI 10.1128/MCB.26.2.389-401.2006, PubMed 16382132

Kazazic M, Roepstorff K, Johannessen LE, Pedersen NM, van Deurs B, Stang E, Madshus IH (2006)
EGF-induced activation of the EGF receptor does not trigger mobilization of caveolae
Traffic, 7 (11), 1518-27
DOI 10.1111/j.1600-0854.2006.00487.x, PubMed 16984407

Publications 2005

Longva KE, Pedersen NM, Haslekås C, Stang E, Madshus IH (2005)
Herceptin-induced inhibition of ErbB2 signaling involves reduced phosphorylation of Akt but not endocytic down-regulation of ErbB2
Int J Cancer, 116 (3), 359-67
DOI 10.1002/ijc.21015, PubMed 15800944

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