Publications
Publications from OUS - Cellular membrane dynamics (Stenmark)
389 publications found
Publications 2020
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Colorectal cysts as a validating tool for CAR therapy
BMC Biotechnol, 20 (1), 30
DOI 10.1186/s12896-020-00623-0, PubMed 32487146 -
Regulation of Expression of Autophagy Genes by Atg8a-Interacting Partners Sequoia, YL-1, and Sir2 in Drosophila
Cell Rep, 31 (8), 107695
DOI 10.1016/j.celrep.2020.107695, PubMed 32460019 -
Structural basis of p62/SQSTM1 helical filaments and their role in cellular cargo uptake
Nat Commun, 11 (1), 440
DOI 10.1038/s41467-020-14343-8, PubMed 31974402 -
Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS signaling to control interferon response
EMBO Rep, 21 (9), e50051
DOI 10.15252/embr.202050051, PubMed 32715615 -
Autoimmunity geneIRGMsuppressescGAS-STINGandRIG-I-MAVSsignaling to control interferon response
EMBO Rep., 21 (9), e50051 -
FGF2-Derived PeptibodyF2-MMAE Conjugate for Targeted Delivery of Cytotoxic Drugs into Cancer Cells Overexpressing FGFR1
Cancers (Basel), 12 (10)
DOI 10.3390/cancers12102992, PubMed 33076489 -
RNA-Binding RING E3-Ligase DZIP3/hRUL138 Stabilizes Cyclin D1 to Drive Cell-Cycle and Cancer Progression
Cancer Res, 81 (2), 315-331
DOI 10.1158/0008-5472.CAN-20-1871, PubMed 33067265 -
Mammalian Atg8 proteins and the autophagy factor IRGM control mTOR and TFEB at a regulatory node critical for responses to pathogens
Nat Cell Biol, 22 (8), 973-985
DOI 10.1038/s41556-020-0549-1, PubMed 32753672 -
Mammalian Atg8-family proteins are upstream regulators of the lysosomalsystem by controlling MTOR and TFEB
Autophagy, 16 (12), 2305-2306
DOI 10.1080/15548627.2020.1837423, PubMed 33070669 -
RabX1 Organizes a Late Endosomal Compartment that Forms Tubular Connections to Lysosomes Consistent with a "Kiss and Run" Mechanism
Curr Biol, 30 (7), 1177-1188.e5
DOI 10.1016/j.cub.2020.01.048, PubMed 32059769 -
Protein crowding mediates membrane remodeling in upstream ESCRT-induced formation of intraluminal vesicles
Proc Natl Acad Sci U S A, 117 (46), 28614-28624
DOI 10.1073/pnas.2014228117, PubMed 33139578 -
Clathrin regulates Wnt/β-catenin signaling by affecting Golgi to plasma membrane transport of transmembrane proteins
J Cell Sci, 133 (13)
DOI 10.1242/jcs.244467, PubMed 32546530 -
Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy
EMBO J, e104948
DOI 10.15252/embj.2020104948, PubMed 33226137 -
Dual Targeting of BRAF and mTOR Signaling in Melanoma Cells with Pyridinyl Imidazole Compounds
Cancers (Basel), 12 (6)
DOI 10.3390/cancers12061516, PubMed 32531927 -
Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
J Cell Biol, 219 (8)
DOI 10.1083/jcb.202003063, PubMed 32479595 -
LRRK2 to the rescue of damaged endomembranes
Embo J., 39 (18), e106162 -
LRRK2 to the rescue of damaged endomembranes
EMBO J, 39 (18), e106162
DOI 10.15252/embj.2020106162, PubMed 32803793 -
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
Nat Cell Biol, 22 (7), 856-867
DOI 10.1038/s41556-020-0537-5, PubMed 32601372 -
Photochemically-Induced Release of Lysosomal Sequestered Sunitinib: Obstacles for Therapeutic Efficacy
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020417, PubMed 32053965 -
STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (8), 868-879
DOI 10.1038/s41590-020-0730-5, PubMed 32690950 -
Author Correction: STEEP mediates STING ER exit and activation of signaling
Nat Immunol, 21 (11), 1468-1469
DOI 10.1038/s41590-020-0803-5, PubMed 32929276
Publications 2019
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Cell Competition Triggers Suicide by Autophagy
Dev Cell, 51 (1), 4-5
DOI 10.1016/j.devcel.2019.09.014, PubMed 31593651 -
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Nat Commun, 10 (1), 5284
DOI 10.1038/s41467-019-13172-8, PubMed 31754102 -
A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling
Cell Rep, 28 (7), 1907-1922.e6
DOI 10.1016/j.celrep.2019.07.025, PubMed 31412255 -
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279 -
The FMRpolyGlycine Protein Mediates Aggregate Formation and Toxicity Independent of the CGG mRNA Hairpin in a Cellular Model for FXTAS
Front Genet, 10, 249
DOI 10.3389/fgene.2019.00249, PubMed 30984240 -
Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites
Nat Commun, 10 (1), 4176
DOI 10.1038/s41467-019-12094-9, PubMed 31519908 -
Correction to: Autophagy and Tumorigenesis in Drosophila
Adv Exp Med Biol, 1167, C1
DOI 10.1007/978-3-030-23629-8_15, PubMed 33306185 -
Autophagy and Tumorigenesis in Drosophila
Adv Exp Med Biol, 1167, 113-127
DOI 10.1007/978-3-030-23629-8_7, PubMed 31520352 -
Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation
Dev Cell, 49 (1), 130-144.e6
DOI 10.1016/j.devcel.2019.01.027, PubMed 30827897 -
Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
Curr Biol, 29 (20), 3538-3548.e7
DOI 10.1016/j.cub.2019.09.025, PubMed 31607533 -
The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress
J Biol Chem, 294 (20), 8197-8217
DOI 10.1074/jbc.RA118.002829, PubMed 30926605 -
The Crohn's Disease Risk Factor IRGM Limits NLRP3 Inflammasome Activation by Impeding Its Assembly and by Mediating Its Selective Autophagy
Mol Cell, 73 (3), 429-445.e7
DOI 10.1016/j.molcel.2018.11.018, PubMed 30612879 -
Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth
Elife, 8
DOI 10.7554/eLife.51063, PubMed 31868590 -
Nrf2 and SQSTM1/p62 jointly contribute to mesenchymal transition and invasion in glioblastoma
Oncogene, 38 (50), 7473-7490
DOI 10.1038/s41388-019-0956-6, PubMed 31444413 -
CRISPR screening using an expanded toolkit of autophagy reporters identifies TMEM41B as a novel autophagy factor
PLoS Biol, 17 (4), e2007044
DOI 10.1371/journal.pbio.2007044, PubMed 30933966 -
The TLR4 adaptor TRAM controls the phagocytosis of Gram-negative bacteria by interacting with the Rab11-family interacting protein 2
PLoS Pathog, 15 (3), e1007684
DOI 10.1371/journal.ppat.1007684, PubMed 30883606 -
WDFY2 restrains matrix metalloproteinase secretion and cell invasion by controlling VAMP3-dependent recycling
Nat Commun, 10 (1), 2850
DOI 10.1038/s41467-019-10794-w, PubMed 31253801 -
Tumor suppression by control of matrix metalloproteinase recycling
Mol Cell Oncol, 6 (6), e1646606
DOI 10.1080/23723556.2019.1646606, PubMed 31692886 -
Cancer Mutations in FGFR2 Prevent a Negative Feedback Loop Mediated by the ERK1/2 Pathway
Cells, 8 (6)
DOI 10.3390/cells8060518, PubMed 31146385 -
Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
NPJ Breast Cancer, 5, 13
DOI 10.1038/s41523-019-0108-8, PubMed 30993194 -
The many functions of ESCRTs
Nat Rev Mol Cell Biol, 21 (1), 25-42
DOI 10.1038/s41580-019-0177-4, PubMed 31705132 -
Crosstalk between p38 and Erk 1/2 in Downregulation of FGF1-Induced Signaling
Int J Mol Sci, 20 (8)
DOI 10.3390/ijms20081826, PubMed 31013829 -
ESCRT-mediated phagophore sealing during mitophagy
Autophagy, 16 (5), 826-841
DOI 10.1080/15548627.2019.1639301, PubMed 31366282
Publications 2018
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Gamma irradiation during gametogenesis in young adult zebrafish causes persistent genotoxicity and adverse reproductive effects
Ecotoxicol Environ Saf, 154, 19-26
DOI 10.1016/j.ecoenv.2018.02.031, PubMed 29453161 -
Protein Tyrosine Phosphatase Receptor Type G (PTPRG) Controls Fibroblast Growth Factor Receptor (FGFR) 1 Activity and Influences Sensitivity to FGFR Kinase Inhibitors
Mol Cell Proteomics, 17 (5), 850-870
DOI 10.1074/mcp.RA117.000538, PubMed 29371290 -
Translocation of Exogenous FGF1 and FGF2 Protects the Cell against Apoptosis Independently of Receptor Activation
J Mol Biol, 430 (21), 4087-4101
DOI 10.1016/j.jmb.2018.08.004, PubMed 30099027 -
Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins
J Cell Biol, 217 (3), 997-1013
DOI 10.1083/jcb.201708039, PubMed 29420192 -
Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics
EMBO J, 37 (13)
DOI 10.15252/embj.201797741, PubMed 29858227 -
Starvation induces rapid degradation of selective autophagy receptors by endosomal microautophagy
J Cell Biol, 217 (10), 3640-3655
DOI 10.1083/jcb.201711002, PubMed 30018090 -
The tankyrase inhibitor G007-LK inhibits small intestine LGR5+ stem cell proliferation without altering tissue morphology
Biol Res, 51 (1), 3
DOI 10.1186/s40659-017-0151-6, PubMed 29316982 -
Endosomal microautophagy is an integrated part of the autophagic response to amino acid starvation
Autophagy, 15 (1), 182-183
DOI 10.1080/15548627.2018.1532265, PubMed 30295124 -
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival
EMBO J, 37 (21)
DOI 10.15252/embj.201899753, PubMed 30314966 -
ESCRTs in membrane sealing
Biochem Soc Trans, 46 (4), 773-778
DOI 10.1042/BST20170435, PubMed 29903934 -
Orchestrating Nuclear Envelope Sealing during Mitosis
Dev Cell, 47 (5), 541-542
DOI 10.1016/j.devcel.2018.11.020, PubMed 30513298 -
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
Nat Commun, 9 (1), 2932
DOI 10.1038/s41467-018-05345-8, PubMed 30050131 -
Proximity Labeling by a Recombinant APEX2-FGF1 Fusion Protein Reveals Interaction of FGF1 with the Proteoglycans CD44 and CSPG4
Biochemistry, 57 (26), 3807-3816
DOI 10.1021/acs.biochem.8b00120, PubMed 29812912
Publications 2017
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Exogenous lysophospholipids with large head groups perturb clathrin-mediated endocytosis
Traffic, 18 (3), 176-191
DOI 10.1111/tra.12468, PubMed 28067430 -
ErbB3 interacts with Hrs and is sorted to lysosomes for degradation
Biochim Biophys Acta Mol Cell Res, 1864 (12), 2241-2252
DOI 10.1016/j.bbamcr.2017.08.011, PubMed 28867611 -
PtdIns3P controls mTORC1 signaling through lysosomal positioning
J Cell Biol, 216 (12), 4217-4233
DOI 10.1083/jcb.201611073, PubMed 29030394 -
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
DOI 10.1038/nature20815, PubMed 28077876 -
Microenvironment and tumors-a nurturing relationship
Autophagy, 13 (7), 1241-1243
DOI 10.1080/15548627.2017.1310361, PubMed 28632995 -
Cytotoxic Conjugates of Fibroblast Growth Factor 2 (FGF2) with Monomethyl Auristatin E for Effective Killing of Cells Expressing FGF Receptors
ACS Omega, 2 (7), 3792-3805
DOI 10.1021/acsomega.7b00116, PubMed 30023704 -
Visualization of PML nuclear import complexes reveals FG-repeat nucleoporins at cargo retrieval sites
Nucleus, 8 (4), 404-420
DOI 10.1080/19491034.2017.1306161, PubMed 28402725 -
Correction: TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
J Cell Sci, 130 (6), 1194
DOI 10.1242/jcs.202499, PubMed 28298613 -
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
Nat Cell Biol, 19 (12), 1412-1423
DOI 10.1038/ncb3631, PubMed 29084199 -
Development of resistance to photodynamic therapy (PDT) in human breast cancer cells is photosensitizer-dependent: Possible mechanisms and approaches for overcoming PDT-resistance
Biochem Pharmacol, 144, 63-77
DOI 10.1016/j.bcp.2017.08.002, PubMed 28784290 -
Suppressing mTORC1 on the lysosome
EMBO J, 36 (13), 1809-1810
DOI 10.15252/embj.201797469, PubMed 28623241 -
Targeting Tankyrase to Fight WNT-dependent Tumours
Basic Clin Pharmacol Toxicol, 121 (2), 81-88
DOI 10.1111/bcpt.12786, PubMed 28371398 -
Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor-Induced Formation of Degradasomes and β-Catenin Degradation
PLoS One, 12 (1), e0170508
DOI 10.1371/journal.pone.0170508, PubMed 28107521 -
The E3 ubiquitin ligase NEDD4 induces endocytosis and lysosomal sorting of connexin 43 to promote loss of gap junctions
J Cell Sci, 130 (17), 2867-2882
DOI 10.1242/jcs.202408, PubMed 28733455 -
Kenny mediates selective autophagic degradation of the IKK complex to control innate immune responses
Nat Commun, 8 (1), 1264
DOI 10.1038/s41467-017-01287-9, PubMed 29097655
Publications 2016
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Novel ESCRT functions in cell biology: spiraling out of control?
Curr Opin Cell Biol, 41, 1-8
DOI 10.1016/j.ceb.2016.03.008, PubMed 27031044 -
Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
Trends Biochem Sci, 42 (1), 42-56
DOI 10.1016/j.tibs.2016.08.016, PubMed 27669649 -
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
J Cell Biol, 212 (5), 499-513
DOI 10.1083/jcb.201507009, PubMed 26929449 -
Mitotic cells form actin-based bridges with adjacent cells to provide intercellular communication during rounding
Cell Cycle, 15 (21), 2943-2957
DOI 10.1080/15384101.2016.1231280, PubMed 27625181 -
Effects of perfluorinated alkyl acids on cellular responses of MCF-10A mammary epithelial cells in monolayers and on acini formation in vitro
Toxicol Lett, 259, 95-107
DOI 10.1016/j.toxlet.2016.08.004, PubMed 27511595 -
Proximity Labeling Reveals Molecular Determinants of FGFR4 Endosomal Transport
J Proteome Res, 15 (10), 3841-3855
DOI 10.1021/acs.jproteome.6b00652, PubMed 27615514 -
PIKfyve inhibition increases exosome release and induces secretory autophagy
Cell Mol Life Sci, 73 (24), 4717-4737
DOI 10.1007/s00018-016-2309-8, PubMed 27438886 -
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
Nat Commun, 7, 13889
DOI 10.1038/ncomms13889, PubMed 28004827 -
Antibody Staining in Drosophila Germaria
Methods Mol Biol, 1457, 19-33
DOI 10.1007/978-1-4939-3795-0_3, PubMed 27557571 -
Focusing the Spotlight on the Zebrafish Intestine to Illuminate Mechanisms of Colorectal Cancer
Adv Exp Med Biol, 916, 411-37
DOI 10.1007/978-3-319-30654-4_18, PubMed 27165364 -
ESCRT proteins restrict constitutive NF-κB signaling by trafficking cytokine receptors
Sci Signal, 9 (411), ra8
DOI 10.1126/scisignal.aad0848, PubMed 26787452 -
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
J Cell Sci, 129 (19), 3562-3573
DOI 10.1242/jcs.190017, PubMed 27562068 -
The Abscission Checkpoint: Making It to the Final Cut
Trends Cell Biol, 27 (1), 1-11
DOI 10.1016/j.tcb.2016.10.001, PubMed 27810282 -
Formation of Tankyrase Inhibitor-Induced Degradasomes Requires Proteasome Activity
PLoS One, 11 (8), e0160507
DOI 10.1371/journal.pone.0160507, PubMed 27482906 -
Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer
Nat Commun, 7, 10318
DOI 10.1038/ncomms10318, PubMed 26754771 -
Plasma membrane repairs by small GTPase Rab3a
J Cell Biol, 213 (6), 613-5
DOI 10.1083/jcb.201606006, PubMed 27325788 -
ER-endosome contact sites in endosome positioning and protrusion outgrowth
Biochem Soc Trans, 44 (2), 441-6
DOI 10.1042/BST20150246, PubMed 27068952 -
Phosphoinositides in membrane contact sites
Biochem Soc Trans, 44 (2), 425-30
DOI 10.1042/BST20150190, PubMed 27068950 -
Phosphoinositides in Control of Membrane Dynamics
Annu Rev Cell Dev Biol, 32, 143-171
DOI 10.1146/annurev-cellbio-111315-125349, PubMed 27576122 -
Genetic Screen in Drosophila Larvae Links ird1 Function to Toll Signaling in the Fat Body and Hemocyte Motility
PLoS One, 11 (7), e0159473
DOI 10.1371/journal.pone.0159473, PubMed 27467079 -
Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow
Cell Cycle, 15 (5), 628-43
DOI 10.1080/15384101.2016.1146834, PubMed 27104745 -
Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3
Biochim Biophys Acta, 1863 (6 Pt A), 1179-88
DOI 10.1016/j.bbamcr.2016.03.011, PubMed 26975582 -
Closing a gap in the nuclear envelope
Curr Opin Cell Biol, 40, 90-97
DOI 10.1016/j.ceb.2016.03.001, PubMed 27016712
Publications 2015
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Surface Trafficking of APP and BACE in Live Cells
Traffic, 16 (6), 655-75
DOI 10.1111/tra.12270, PubMed 25712587 -
Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy
Autophagy, 11 (9), 1458-70
DOI 10.1080/15548627.2015.1067359, PubMed 26207339 -
Enrichment of nuclear S100A4 during G2/M in colorectal cancer cells: possible association with cyclin B1 and centrosomes
Clin Exp Metastasis, 32 (8), 755-67
DOI 10.1007/s10585-015-9742-1, PubMed 26349943 -
ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo
PLoS Genet, 11 (1), e1004904
DOI 10.1371/journal.pgen.1004904, PubMed 25635693 -
Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline
Development, 142 (23), 4107-18
DOI 10.1242/dev.124370, PubMed 26628094 -
Dynamic Escherichia coli SeqA complexes organize the newly replicated DNA at a considerable distance from the replisome
Nucleic Acids Res, 43 (5), 2730-43
DOI 10.1093/nar/gkv146, PubMed 25722374 -
p62/Sequestosome-1, Autophagy-related Gene 8, and Autophagy in Drosophila Are Regulated by Nuclear Factor Erythroid 2-related Factor 2 (NRF2), Independent of Transcription Factor TFEB
J Biol Chem, 290 (24), 14945-62
DOI 10.1074/jbc.M115.656116, PubMed 25931115 -
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth
Nature, 520 (7546), 234-8
DOI 10.1038/nature14359, PubMed 25855459 -
ER-endosome contact sites: molecular compositions and functions
EMBO J, 34 (14), 1848-58
DOI 10.15252/embj.201591481, PubMed 26041457 -
CSPP-L Associates with the Desmosome of Polarized Epithelial Cells and Is Required for Normal Spheroid Formation
PLoS One, 10 (8), e0134789
DOI 10.1371/journal.pone.0134789, PubMed 26241740 -
Structure, Dynamics, and Functionality of Tankyrase Inhibitor-Induced Degradasomes
Mol Cancer Res, 13 (11), 1487-501
DOI 10.1158/1541-7786.MCR-15-0125, PubMed 26124443 -
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
Nature, 522 (7555), 231-5
DOI 10.1038/nature14408, PubMed 26040712 -
The novel HSP90 inhibitor NVP-AUY922 shows synergistic anti-leukemic activity with cytarabine in vivo
Exp Cell Res, 340 (2), 220-6
DOI 10.1016/j.yexcr.2015.12.017, PubMed 26748184 -
Cellular functions of Rab GTPases at a glance
J Cell Sci, 128 (17), 3171-6
DOI 10.1242/jcs.166074, PubMed 26272922
Publications 2014
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Trans-splicing and operons in metazoans: translational control in maternally regulated development and recovery from growth arrest
Mol Biol Evol, 32 (3), 585-99
DOI 10.1093/molbev/msu336, PubMed 25525214 -
Investigating spermatogenesis in Drosophila melanogaster
Methods, 68 (1), 218-27
DOI 10.1016/j.ymeth.2014.04.020, PubMed 24798812 -
Promyelocytic leukemia bodies tether to early endosomes during mitosis
Cell Cycle, 13 (11), 1749-55
DOI 10.4161/cc.28653, PubMed 24675887 -
The ether lipid precursor hexadecylglycerol stimulates the release and changes the composition of exosomes derived from PC-3 cells
J Biol Chem, 290 (7), 4225-37
DOI 10.1074/jbc.M114.593962, PubMed 25519911 -
An ER clamp for endosome fission
EMBO J, 34 (2), 136-7
DOI 10.15252/embj.201490707, PubMed 25502456 -
Regulation of the Tumor-Suppressor Function of the Class III Phosphatidylinositol 3-Kinase Complex by Ubiquitin and SUMO
Cancers (Basel), 7 (1), 1-29
DOI 10.3390/cancers7010001, PubMed 25545884 -
Association of CHMP4B and autophagy with micronuclei: implications for cataract formation
Biomed Res Int, 2014, 974393
DOI 10.1155/2014/974393, PubMed 24741567 -
CK2 involvement in ESCRT-III complex phosphorylation
Arch Biochem Biophys, 545, 83-91
DOI 10.1016/j.abb.2014.01.006, PubMed 24440309 -
Nucleolin regulates phosphorylation and nuclear export of fibroblast growth factor 1 (FGF1)
PLoS One, 9 (3), e90687
DOI 10.1371/journal.pone.0090687, PubMed 24595027 -
Ribosomal readthrough at a short UGA stop codon context triggers dual localization of metabolic enzymes in Fungi and animals
PLoS Genet, 10 (10), e1004685
DOI 10.1371/journal.pgen.1004685, PubMed 25340584 -
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4
Nat Cell Biol, 16 (6), 550-60
DOI 10.1038/ncb2959, PubMed 24814515 -
Monitoring phosphatidylinositol 3-phosphate in multivesicular endosome biogenesis
Methods Enzymol, 534, 3-23
DOI 10.1016/B978-0-12-397926-1.00001-9, PubMed 24359945
Publications 2013
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Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
Dev Biol, 377 (1), 9-20
DOI 10.1016/j.ydbio.2013.02.021, PubMed 23499247 -
TRAF6 mediates ubiquitination of KIF23/MKLP1 and is required for midbody ring degradation by selective autophagy
Autophagy, 9 (12), 1955-64
DOI 10.4161/auto.26085, PubMed 24128730 -
RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789
Oncogene, 33 (40), 4823-36
DOI 10.1038/onc.2013.425, PubMed 24141780 -
Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
Bioessays, 35 (10), 900-12
DOI 10.1002/bies.201300064, PubMed 23881848
Publications 2012
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Antibody crossreactivity between the tumour suppressor PHLPP1 and the proto-oncogene β-catenin
EMBO Rep, 14 (1), 10-1
DOI 10.1038/embor.2012.188, PubMed 23229585 -
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
Traffic, 13 (11), 1547-63
DOI 10.1111/j.1600-0854.2012.01400.x, PubMed 22816767
Publications 2011
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Cell biology. Growth signaling from inside
Science, 334 (6056), 611-2
DOI 10.1126/science.1214355, PubMed 22053037 -
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
DOI 10.4161/cib.4.1.13550, PubMed 21509167 -
Basic and discovery-based translational research on cancer was on the agenda at the 21st Congress of the European Association for Cancer Research (EACR) in Oslo, Norway, 26-29 June 2010
Clin. Transl. Oncol., 13 (1), 1-2 -
Cell differentiation: midbody remnants - junk or fate factors?
Curr Biol, 21 (23), R958-60
DOI 10.1016/j.cub.2011.10.035, PubMed 22153165 -
Harald Stenmark: hands on FYVE-fingers. Interview by Caitlin Sedwick
J Cell Biol, 192 (4), 544-5
DOI 10.1083/jcb.1924pi, PubMed 21339328
Publications 2010
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Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
DOI 10.1016/j.cub.2010.03.068, PubMed 20451383 -
Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway
J Infect Dis, 201 (5), 783-92
DOI 10.1086/650493, PubMed 20121435 -
ESCRT & Co
Biol Cell, 102 (5), 293-318
DOI 10.1042/BC20090161, PubMed 20222872 -
p62, an autophagy hero or culprit?
Nat Cell Biol, 12 (3), 207-9
DOI 10.1038/ncb0310-207, PubMed 20190829 -
Cytokinesis and cancer (vol 584, pg 2652, 2010)
FEBS Lett., 584 (18), 4128
Publications 2009
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Seeing is believing
Nat Rev Mol Cell Biol, 10 (9), 582
DOI 10.1038/nrm2747, PubMed 19702012 -
Rab GTPases as coordinators of vesicle traffic
Nat Rev Mol Cell Biol, 10 (8), 513-25
DOI 10.1038/nrm2728, PubMed 19603039 -
Multivesicular endosome biogenesis in the absence of ESCRTs
Traffic, 10 (7), 925-37
DOI 10.1111/j.1600-0854.2009.00920.x, PubMed 19490536 -
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
Histochem Cell Biol, 133 (1), 41-55
DOI 10.1007/s00418-009-0643-8, PubMed 19830447
Publications 2008
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Membranes and organelles
Curr Opin Cell Biol, 20 (4), 357-9
DOI 10.1016/j.ceb.2008.06.005, PubMed 18588977 -
ESCRTing autophagic clearance of aggregating proteins
Autophagy, 4 (2), 233-236 -
ESCRT functions in autophagy and associated disease
Cell Cycle, 7 (9), 1166-72
DOI 10.4161/cc.7.9.5784, PubMed 18418046
Publications 2007
-
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
DOI 10.1615/critrevoncog.v13.i1.20, PubMed 17956217 -
ESCRTs
Curr Biol, 17 (2), R42-3
DOI 10.1016/j.cub.2006.12.009, PubMed 17240322 -
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
DOI 10.1016/j.yexcr.2007.10.014, PubMed 18031739 -
Developmental biology: moonlighting at the pole
Nature, 445 (7127), 497-9
DOI 10.1038/445497a, PubMed 17268460 -
Genetic modifiers of the Drosophila blue cheese gene link defects in lysosomal transport with decreased life span and altered ubiquitinated-protein profiles
Genetics, 176 (2), 1283-97
DOI 10.1534/genetics.106.065011, PubMed 17435236 -
Stimulating the cell's appetite for itself
Nat Chem Biol, 3 (6), 304-6
DOI 10.1038/nchembio0607-304, PubMed 17510644
Publications 2006
-
The function of ubiquitin-binding protein complexes in endocytic downregulation of growth factor receptors
Crit Rev Oncog, 12 (3-4), 301; discussion 301-2
DOI 10.1615/critrevoncog.v12.i3-4.90, PubMed 17425510 -
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
DOI 10.1091/mbc.e05-10-0915, PubMed 16554368 -
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
Gene, 371 (1), 34-41
DOI 10.1016/j.gene.2005.11.009, PubMed 16448788 -
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
DOI 10.1038/ncb1106-1218, PubMed 17077855 -
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
Exp Cell Res, 312 (11), 2018-27
DOI 10.1016/j.yexcr.2006.03.002, PubMed 16600212 -
How a RING finger protein and a steroid hormone control autophagy
Autophagy, 2 (4), 321-2
DOI 10.4161/auto.3091, PubMed 16874068 -
Regulation of membrane traffic by phosphoinositide 3-kinases
J Cell Sci, 119 (Pt 4), 605-14
DOI 10.1242/jcs.02855, PubMed 16467569 -
Hrs makes receptors silent: a key to endosomal protein sorting
Crit Rev Oncog, 12 (3-4), 295, discussion 295-6
DOI 10.1615/critrevoncog.v12.i3-4.70, PubMed 17425508 -
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
DOI 10.1016/j.tibs.2006.07.009, PubMed 16901703 -
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
DOI 10.1242/jcs.02978, PubMed 16720641 -
Fab1 phosphatidylinositol 3-phosphate 5-kinase controls trafficking but not silencing of endocytosed receptors
Mol Biol Cell, 17 (9), 3989-4001
DOI 10.1091/mbc.e06-03-0239, PubMed 16837550 -
Analyzing phosphoinositides and their interacting proteins
Nat Methods, 3 (4), 251-8
DOI 10.1038/nmeth867, PubMed 16554828 -
CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4
EMBO J, 25 (16), 3738-49
DOI 10.1038/sj.emboj.7601267, PubMed 16888620 -
Endosomal and non-endosomal functions of ESCRT proteins
Trends Cell Biol, 16 (6), 317-26
DOI 10.1016/j.tcb.2006.04.004, PubMed 16716591 -
Functional diversity of FGF-2 isoforms by intracellular sorting
Bioessays, 28 (5), 504-14
DOI 10.1002/bies.20405, PubMed 16615083 -
Different abilities of the four FGFRs to mediate FGF-1 translocation are linked to differences in the receptor C-terminal tail
J Cell Sci, 119 (Pt 20), 4332-41
DOI 10.1242/jcs.03209, PubMed 17003104 -
FGF-1 and FGF-2 require the cytosolic chaperone Hsp90 for translocation into the cytosol and the cell nucleus
J Biol Chem, 281 (16), 11405-12
DOI 10.1074/jbc.M600477200, PubMed 16495214
Publications 2005
-
Alix regulates cortical actin and the spatial distribution of endosomes
J Cell Sci, 118 (Pt 12), 2625-35
DOI 10.1242/jcs.02382, PubMed 15914539 -
When and from whom do female pied flycatchers (Ficedula hypoleuca) solicit copulations
Behaviour, 142, 1059-1076 -
Manipulation of male quality in wild tits: effects on paternity loss
Behav. Ecol., 16 (4), 747-754 -
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
DOI 10.1074/jbc.M501510200, PubMed 15755741 -
Individual fluctuating asymmetry in pied flycatchers (Ficedula hypoleuca) persists across moults, but is not heritable and not related to fitness
Evol. Ecol. Res., 7 (3), 381-406 -
Two nuclear localization signals required for transport from the cytosol to the nucleus of externally added FGF-1 translocated into cells
Biochemistry, 44 (16), 6071-80
DOI 10.1021/bi047403m, PubMed 15835896
Publications 2004
-
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
DOI 10.1091/mbc.e04-03-0250, PubMed 15240819 -
Defective downregulation of receptor tyrosine kinases in cancer
EMBO J, 23 (14), 2707-12
DOI 10.1038/sj.emboj.7600292, PubMed 15229652 -
Protein targeting to endosomes and phagosomes via FYVE and PX domains
Curr Top Microbiol Immunol, 282, 89-115
DOI 10.1007/978-3-642-18805-3_4, PubMed 14594215 -
Early learning affects social dominance: interspecifically cross-fostered tits become subdominant
Behav. Ecol., 15 (2), 262-268 -
The history of ricin, abrin and related toxins
Toxicon, 44 (4), 361-70
DOI 10.1016/j.toxicon.2004.05.003, PubMed 15302520 -
Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway
Dev Cell, 7 (2), 179-92
DOI 10.1016/j.devcel.2004.07.005, PubMed 15296715 -
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
J Cell Sci, 117 (Pt 18), 4239-51
DOI 10.1242/jcs.01287, PubMed 15292400 -
The structure of an endosomal protein sorter
Dev Cell, 7 (4), 457-8
DOI 10.1016/j.devcel.2004.09.007, PubMed 15469831 -
Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus
J Cell Sci, 117 (Pt 9), 1807-19
DOI 10.1242/jcs.01047, PubMed 15075241 -
Phosphorylation-regulated nucleocytoplasmic trafficking of internalized fibroblast growth factor-1
Mol Biol Cell, 16 (2), 794-810
DOI 10.1091/mbc.e04-05-0389, PubMed 15574884 -
Signaling, internalization, and intracellular activity of fibroblast growth factor
Curr Top Microbiol Immunol, 286, 45-79
DOI 10.1007/978-3-540-69494-6_3, PubMed 15645710
Publications 2003
-
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
J Cell Biol, 162 (3), 435-42
DOI 10.1083/jcb.200302131, PubMed 12900395 -
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
J Biol Chem, 278 (14), 12513-21
DOI 10.1074/jbc.M210843200, PubMed 12551915 -
Thermal depolymerization of alginate in the solid state
Carbohydr. Polym., 54 (4), 431-438 -
Peroxisomal targeting as a tool for assaying potein-protein interactions in the living cell: cytokine-independent survival kinase (CISK) binds PDK-1 in vivo in a phosphorylation-dependent manner
J Biol Chem, 279 (6), 4794-801
DOI 10.1074/jbc.M309653200, PubMed 14604990 -
Transport of exogenous growth factors and cytokines to the cytosol and to the nucleus
Physiol Rev, 83 (1), 163-82
DOI 10.1152/physrev.00021.2002, PubMed 12506129 -
Protein sorting into multivesicular endosomes
Curr Opin Cell Biol, 15 (4), 446-55
DOI 10.1016/s0955-0674(03)00080-2, PubMed 12892785 -
Time resolved spectroscopic optical coherence tomography for diffusion measurements
P SOC PHOTO-OPT INS, 4956, 197-204
Publications 2002
-
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
Eur J Biochem, 269 (16), 3881-7
DOI 10.1046/j.1432-1033.2002.03046.x, PubMed 12180964 -
A short form of the heparin-binding EGF-like growth factor with a changed EGF domain
Mol. Biol., 36 (1), 58-64 -
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Nat Cell Biol, 4 (5), 394-8
DOI 10.1038/ncb791, PubMed 11988743 -
Hrs and endocytic sorting of ubiquitinated membrane proteins
Cell Struct Funct, 27 (6), 403-8
DOI 10.1247/csf.27.403, PubMed 12576633 -
Binding of FGF-1 variants to protein kinase CK2 correlates with mitogenicity
EMBO J, 21 (15), 4058-69
DOI 10.1093/emboj/cdf402, PubMed 12145206 -
Identification of ribosome-binding protein p34 as an intracellular protein that binds acidic fibroblast growth factor
J Biol Chem, 277 (26), 23864-71
DOI 10.1074/jbc.M112193200, PubMed 11964394 -
The phosphatidylinositol 3-phosphate-binding FYVE finger
FEBS Lett, 513 (1), 77-84
DOI 10.1016/s0014-5793(01)03308-7, PubMed 11911884 -
Retrograde transport of ricin
Int J Med Microbiol, 291 (6-7), 517-21
DOI 10.1078/1438-4221-00161, PubMed 11890552
Publications 2001
-
Two farms of the heparin-binding EGF-like growth factor precursor, a receptor for diphtheria toxin
Mol. Biol., 35 (1), 122-129 -
[Two forms of precursors of a heparin-binding EGF-like growth factor-diphtheria toxin receptor]
Mol Biol (Mosk), 35 (1), 136-45
PubMed 11234372 -
Ricin
Toxicon, 39 (11), 1723-8
DOI 10.1016/s0041-0101(01)00158-1, PubMed 11595634 -
Microbiology. Fighting anthrax with a mutant toxin
Science, 292 (5517), 647-8
DOI 10.1126/science.1060857, PubMed 11330322 -
Hrs recruits clathrin to early endosomes
EMBO J, 20 (17), 5008-21
DOI 10.1093/emboj/20.17.5008, PubMed 11532964 -
Function of Hrs in endocytic trafficking and signalling
Biochem Soc Trans, 29 (Pt 4), 472-5
DOI 10.1042/bst0290472, PubMed 11498011 -
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
J Cell Sci, 114 (Pt 12), 2255-63
PubMed 11493665 -
PX domains: attracted by phosphoinositides
Nat Cell Biol, 3 (8), E179-82
DOI 10.1038/35087112, PubMed 11483972 -
The role of phosphoinositides in membrane transport
Curr Opin Cell Biol, 13 (4), 485-92
DOI 10.1016/s0955-0674(00)00240-4, PubMed 11454456 -
DNA binding-independent transcriptional activation by the androgen receptor through triggering of coactivators
J Biol Chem, 276 (33), 31030-6
DOI 10.1074/jbc.M104310200, PubMed 11429409 -
Introduction. Trafficking of lipids
Semin Cell Dev Biol, 12 (2), 135-7
DOI 10.1006/scdb.2000.0230, PubMed 11292379 -
Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate
Semin Cell Dev Biol, 12 (2), 193-9
DOI 10.1006/scdb.2000.0236, PubMed 11292385 -
The Rab GTPase family
Genome Biol., 2 (5), 3007.1 -
The Rab GTPase family
Genome Biol, 2 (5), REVIEWS3007
DOI 10.1186/gb-2001-2-5-reviews3007, PubMed 11387043
Publications 2000
-
Probing pores with peptide plugs. Topology of membrane-inserted diphtheria toxin
J Gen Physiol, 115 (4), 417-20
DOI 10.1085/jgp.115.4.417, PubMed 10736309 -
Palaeoecological investigations towards the reconstruction of the history of forest clearances and coastal heathlands in south-western Norway
Veg. Hist. Archaeobot., 9 (4), 189-204 -
Mutational analysis of the androgen receptor AF-2 (activation function 2) core domain reveals functional and mechanistic differences of conserved residues compared with other nuclear receptors
Mol Endocrinol, 14 (10), 1603-17
DOI 10.1210/mend.14.10.0544, PubMed 11043576 -
Cycling lipids
Curr Biol, 10 (2), R57-9
DOI 10.1016/s0960-9822(00)00279-7, PubMed 10662657 -
Externally added aFGF mutants do not require extensive unfolding for transport to the cytosol and the nucleus in NIH/3T3 cells
Biochemistry, 39 (49), 15091-100
DOI 10.1021/bi001831k, PubMed 11106487
Publications 1999
-
[The Nobel Prize in physiology and medicine]
Tidsskr Nor Laegeforen, 119 (30), 4450
PubMed 10827478 -
The Rab5 effector EEA1 interacts directly with syntaxin-6
J Biol Chem, 274 (41), 28857-60
DOI 10.1074/jbc.274.41.28857, PubMed 10506127 -
FYVE-finger proteins--effectors of an inositol lipid
J Cell Sci, 112 ( Pt 23), 4175-83
PubMed 10564636 -
Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol
J Biol Chem, 274 (48), 34443-9
DOI 10.1074/jbc.274.48.34443, PubMed 10567425 -
Following angiogenin during angiogenesis: a journey from the cell surface to the nucleolus
Arch Immunol Ther Exp (Warsz), 47 (5), 299-305
PubMed 10604235
Publications 1998
-
CREB binding protein is a coactivator for the androgen receptor and mediates cross-talk with AP-1
J Biol Chem, 273 (48), 31853-9
DOI 10.1074/jbc.273.48.31853, PubMed 9822653 -
FYVE fingers bind PtdIns(3)P
Nature, 394 (6692), 432-3
DOI 10.1038/28767, PubMed 9697764 -
Existence of two crystal structures of the complex alpha-D-glucose center dot NaCl center dot H2O (2 : 1 : 1) verified by three-beam diffraction experiments
Acta Crystallogr. Sect. A, 54, 338-347 -
Shiga and Shiga-like toxins
RECENT ADVANCES IN THE PATHOGENESIS OF GASTROINTESTINAL BACTERIAL INFECTIONS, 143-153 -
Syntaxin-16, a putative Golgi t-SNARE
Eur J Cell Biol, 75 (3), 223-31
DOI 10.1016/S0171-9335(98)80116-7, PubMed 9587053 -
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Nature, 394 (6692), 494-8
DOI 10.1038/28879, PubMed 9697774 -
Novel protein toxin-based strategy for development of cytotoxic T lymphocyte vaccines
Arch Immunol Ther Exp (Warsz), 46 (6), 341-6
PubMed 9883312
Publications 1997
-
[Self-inhibiting N-glycosidase activity of shigella toxin]
Mol Biol (Mosk), 31 (3), 528-35
PubMed 9297098 -
Self-inhibition of N-glycosidase activity of shiga toxin
Mol. Biol., 31 (3), 441-447 -
Diphtheria toxin as a molecular tool in the study of acidic fibroblast growth factor signalling
Arch Immunol Ther Exp (Warsz), 45 (5-6), 391-409
PubMed 9437495
Publications 1996
-
Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger
J Biol Chem, 271 (39), 24048-54
DOI 10.1074/jbc.271.39.24048, PubMed 8798641 -
Retrograde transport of acidic fibroblast growth factor as a part of the growth factor signaling
Arch Immunol Ther Exp (Warsz), 44 (4), 201-7
PubMed 9017159 -
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization
Mol Cell Biol, 16 (1), 270-80
DOI 10.1128/mcb.16.1.270, PubMed 8524304
Publications 1995
-
CELL PENETRATION OF BACTERIAL PROTEIN TOXINS - RESPONSE
Trends Microbiol., 3 (5), 167-168 -
Translocation of cytosol of exogenous, CAAX-tagged acidic fibroblast growth factor
J Biol Chem, 270 (51), 30680-5
DOI 10.1074/jbc.270.51.30680, PubMed 8530506
Publications 1994
-
Dual mode of signal transduction by externally added acidic fibroblast growth factor
Cell, 76 (6), 1039-51
DOI 10.1016/0092-8674(94)90381-6, PubMed 7511061
Publications 1993
-
PRELYSOSOMAL DEGRADATION IN RAT-LIVER ENDOTHELIAL-CELLS
CELLS OF THE HEPATIC SINUSOID, VOL 4, 426-430 -
Rapid increase in pH set-point of the Na(+)-in-dependent chloride/bicarbonate antiporter in Vero cells exposed to heat shock
J Membr Biol, 134 (2), 143-53
DOI 10.1007/BF00232750, PubMed 8411117 -
Protein toxins acting on intracellular targets: cellular uptake and translocation to the cytosol
Med Microbiol Immunol, 182 (2), 51-61
DOI 10.1007/BF00189373, PubMed 8392658
Publications 1992
-
Genetically engineered toxins in perspective
Targeted Diagn Ther, 7, 465-77
PubMed 1633307 -
Association between diphtheria toxin A- and B-fragment and their fusion proteins
Biochem J, 281 ( Pt 3), 619-25
DOI 10.1042/bj2810619, PubMed 1536643 -
Interactions of diphtheria toxin B-fragment with cells. Role of amino- and carboxyl-terminal regions
J Biol Chem, 267 (13), 8957-62
PubMed 1374382 -
Tight folding of acidic fibroblast growth factor prevents its translocation to the cytosol with diphtheria toxin as vector
EMBO J, 11 (13), 4835-42
DOI 10.1002/j.1460-2075.1992.tb05589.x, PubMed 1281450
Publications 1991
-
Evidence for involvement of protein kinase C in regulation of intracellular pH by Cl-/HCO-3 antiport
J Membr Biol, 119 (2), 179-86
DOI 10.1007/BF01871417, PubMed 2046087 -
Bacterial protein toxins acting on intracellular targets
Semin Cell Biol, 2 (1), 7-14
PubMed 1954345 -
Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
J Cell Biol, 113 (5), 1025-32
DOI 10.1083/jcb.113.5.1025, PubMed 2040642 -
Elimination of the disulphide bridge in fragment B of diphtheria toxin: effect on membrane insertion, channel formation, and ATP binding
Mol Microbiol, 5 (3), 595-606
DOI 10.1111/j.1365-2958.1991.tb00730.x, PubMed 1646374 -
Internalization and action of an immunotoxin containing mistletoe lectin A-chain
Cancer Res, 51 (3), 916-20
PubMed 1988131
Publications 1990
-
Translocation of diphtheria toxin to the cytosol and formation of cation selective channels
J Physiol (Paris), 84 (3), 191-6
PubMed 1705980 -
Protein toxins with intracellular targets
Microb Pathog, 8 (3), 163-8
DOI 10.1016/0882-4010(90)90043-p, PubMed 1696341
Publications 1989
-
Immunotoxins--entry into cells and mechanisms of action
Immunol Today, 10 (9), 291-5
PubMed 2686677 -
FORMATION OF ACTIVE DIPHTHERIA-TOXIN INVITRO BASED ON LIGATED FRAGMENTS OF CLONED MUTANT-GENES
J. Biol. Chem., 264 (22), 12749-12751 -
Formation of active diphtheria toxin in vitro based on ligated fragments of cloned mutant genes
J Biol Chem, 264 (22), 12747-51
PubMed 2753882 -
Permeabilization of the plasma membrane by deletion mutants of diphtheria toxin
EMBO J, 8 (10), 2849-53
DOI 10.1002/j.1460-2075.1989.tb08432.x, PubMed 2479538 -
[Endocytosis, intracellular transport and sorting of proteins]
Nord Med, 104 (1), 9-11
PubMed 2911460
Publications 1988
-
Diphtheria toxin entry: protein translocation in the reverse direction
Trends Biochem Sci, 13 (9), 348-51
DOI 10.1016/0968-0004(88)90105-3, PubMed 3072713 -
How protein toxins enter and kill cells
Cancer Treat Res, 37, 39-73
DOI 10.1007/978-1-4613-1083-9_4, PubMed 2908634 -
Requirement of specific receptors for efficient translocation of diphtheria toxin A fragment across the plasma membrane
J Biol Chem, 263 (26), 13449-55
PubMed 3417666
Publications 1987
-
Formation and activity of covalent conjugates of poliovirus and ligands binding to cell surface structures
Exp Cell Res, 170 (2), 483-90
DOI 10.1016/0014-4827(87)90322-3, PubMed 3036553 -
Selective inhibition of sodium-linked and sodium-independent bicarbonate/chloride antiport in Vero cells
J Biol Chem, 262 (16), 7486-91
PubMed 3584123 -
Effect of reduced endocytosis induced by hypotonic shock and potassium depletion on the infection of Hep 2 cells by picornaviruses
J Cell Physiol, 131 (1), 14-22
DOI 10.1002/jcp.1041310104, PubMed 3032992 -
Effect of potassium depletion of Hep 2 cells on intracellular pH and on chloride uptake by anion antiport
J Cell Physiol, 131 (1), 6-13
DOI 10.1002/jcp.1041310103, PubMed 3571337 -
Cell-mediated reduction of the interfragment disulfide in nicked diphtheria toxin. A new system to study toxin entry at low pH
J Biol Chem, 262 (21), 10339-45
PubMed 3112141 -
Closing in on ricin action
Nature, 328 (6130), 474-5
DOI 10.1038/328474b0, PubMed 3614350 -
Bicarbonate/chloride antiport in Vero cells: II. Mechanisms for bicarbonate-dependent regulation of intracellular pH
J Cell Physiol, 132 (2), 192-202
DOI 10.1002/jcp.1041320203, PubMed 3624315 -
Effect of intracellular pH on the rate of chloride uptake and efflux in different mammalian cell lines
Biochemistry, 26 (10), 2778-85
DOI 10.1021/bi00384a019, PubMed 3606992 -
Acidification of the cytosol inhibits endocytosis from coated pits
J Cell Biol, 105 (2), 679-89
DOI 10.1083/jcb.105.2.679, PubMed 2887575 -
Bicarbonate/chloride antiport in Vero cells: I. Evidence for both sodium-linked and sodium-independent exchange
J Cell Physiol, 132 (2), 183-91
DOI 10.1002/jcp.1041320202, PubMed 3624314 -
Delivery of internalized ricin from endosomes to cisternal Golgi elements is a discontinuous, temperature-sensitive process
Exp Cell Res, 171 (1), 137-52
DOI 10.1016/0014-4827(87)90257-6, PubMed 3622628
Publications 1986
-
Interactions between diphtheria toxin entry and anion transport in vero cells. III. Effect on toxin binding and anion transport of tumor-promoting phorbol esters, vanadate, fluoride, and salicylate
J Biol Chem, 261 (4), 1562-9
PubMed 3632976 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. I. Anion antiport in Vero cells
J Biol Chem, 261 (4), 1542-52
PubMed 3944100 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. II. Inhibition of anion antiport by diphtheria toxin
J Biol Chem, 261 (4), 1553-61
PubMed 3944101 -
pH-regulated anion antiport in nucleated mammalian cells
J Cell Biol, 102 (3), 967-71
DOI 10.1083/jcb.102.3.967, PubMed 3949885 -
Interactions between diphtheria toxin entry and anion transport in Vero cells. IV. Evidence that entry of diphtheria toxin is dependent on efficient anion transport
J Biol Chem, 261 (4), 1570-5
PubMed 2418015 -
Ability of inhibitors of glycosylation and protein synthesis to sensitize cells to abrin, ricin, Shigella toxin, and Pseudomonas toxin
Cancer Res, 46 (12 Pt 1), 6418-22
PubMed 3096563 -
REQUIREMENT OF A TRANSMEMBRANE PH GRADIENT FOR THE ENTRY OF DIPHTHERIA-TOXIN INTO CELLS AT LOW PH
J. Biol. Chem., 261 (25), 1639-1644 -
Requirement of a transmembrane pH gradient for the entry of diphtheria toxin into cells at low pH
J Biol Chem, 261 (25), 11639-44
PubMed 3745160 -
Routing of internalized ricin and ricin conjugates to the Golgi complex
J Cell Biol, 102 (1), 37-47
DOI 10.1083/jcb.102.1.37, PubMed 3001103
Publications 1985
-
Entry of diphtheria toxin linked to concanavalin A into primate and murine cells
J Cell Physiol, 122 (2), 193-9
DOI 10.1002/jcp.1041220205, PubMed 3844014 -
Tumor-promoting phorbol esters and vanadate alter the sensitivity of HeLa S3 cells to poliovirus type 1
Exp Cell Res, 160 (1), 240-4
DOI 10.1016/0014-4827(85)90253-8, PubMed 2995095 -
Evidence that membrane phospholipids and protein are required for binding of diphtheria toxin in Vero cells
Biochim Biophys Acta, 846 (3), 334-41
DOI 10.1016/0167-4889(85)90003-5, PubMed 4041483 -
ENTRY MECHANISMS OF PROTEIN TOXINS AND PICORNAVIRUSES
Biochem. Soc. Symp. (50), 171-191 -
Entry mechanisms of protein toxins and picornaviruses
Biochem Soc Symp, 50, 171-91
PubMed 3915869 -
Effect of the chaotropic anions thiocyanate and perchlorate on the entry of ricin into Vero cells
Biochem J, 228 (2), 521-3
DOI 10.1042/bj2280521, PubMed 2990449 -
Effect of potassium depletion of cells on their sensitivity to diphtheria toxin and pseudomonas toxin
J Cell Physiol, 124 (1), 54-60
DOI 10.1002/jcp.1041240110, PubMed 3930519 -
Properties of volkensin, a toxic lectin from Adenia volkensii
J Biol Chem, 260 (27), 14589-95
PubMed 3932357 -
PROPERTIES OF VOLKENSIN, A TOXIC LECTIN FROM ADENIA-VOLKENSII
J. Biol. Chem., 260 (27), 4589-4595 -
Receptor-mediated endocytosis of a ricin-colloidal gold conjugate in vero cells. Intracellular routing to vacuolar and tubulo-vesicular portions of the endosomal system
Exp Cell Res, 159 (2), 287-304
DOI 10.1016/s0014-4827(85)80003-3, PubMed 2863159
Publications 1984
-
Requirements for entry of poliovirus RNA into cells at low pH
EMBO J, 3 (9), 1945-50
DOI 10.1002/j.1460-2075.1984.tb02074.x, PubMed 6092049 -
Different pH requirements for entry of the two picornaviruses, human rhinovirus 2 and murine encephalomyocarditis virus
Virology, 139 (2), 346-57
DOI 10.1016/0042-6822(84)90380-5, PubMed 6097029 -
Mechanism of entry into the cytosol of poliovirus type 1: requirement for low pH
J Cell Biol, 98 (4), 1194-200
DOI 10.1083/jcb.98.4.1194, PubMed 6325467 -
Dimethyl sulphoxide protects cells against polypeptide toxins and poliovirus
Biochem J, 219 (3), 935-40
DOI 10.1042/bj2190935, PubMed 6331401 -
Anion requirement and effect of anion transport inhibitors on the response of vero cells to diphtheria toxin and modeccin
J Cell Physiol, 119 (1), 7-14
DOI 10.1002/jcp.1041190103, PubMed 6707104 -
Receptor-mediated entry of protein toxins into cells
Acta Histochem Suppl, 29, 79-94
PubMed 6144140 -
Evidence that diphtheria toxin and modeccin enter the cytosol from different vesicular compartments
J Cell Biol, 98 (3), 963-70
DOI 10.1083/jcb.98.3.963, PubMed 6699094 -
Effect of malignant transformation, retinoic acid, trifluoperazine, and N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide (W7) on the sensitivity of rodent cells to Pseudomonas toxin
Cancer Res, 44 (11), 4919-23
PubMed 6435858 -
Calmodulin antagonists sensitize cells to pseudomonas toxin
J Cell Physiol, 119 (1), 15-22
DOI 10.1002/jcp.1041190104, PubMed 6707099
Publications 1983
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Animal toxicity of Shigella dysenteriae cytotoxin: evidence that the neurotoxic, enterotoxic, and cytotoxic activities are due to one toxin
J Immunol, 130 (1), 380-4
PubMed 6336624 -
Entry of Shigella dysenteriae toxin into HeLa cells
Infect Immun, 42 (2), 771-7
DOI 10.1128/IAI.42.2.771-777.1983, PubMed 6358031 -
Preparation and properties of a hybrid toxin of modeccin A-chain and ricin B-chain
Biochim Biophys Acta, 761 (3), 296-302
DOI 10.1016/0304-4165(83)90080-6, PubMed 6652111 -
Dansylcadaverine eliminates calmodulin stimulation of phosphodiesterase
Biochem Biophys Res Commun, 117 (2), 562-7
DOI 10.1016/0006-291x(83)91237-8, PubMed 6318763
Publications 1982
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The toxic lectin modeccin
Methods Enzymol, 83, 357-62
DOI 10.1016/0076-6879(82)83030-9, PubMed 6178935 -
Isolation and characterization of viscumin, a toxic lectin from Viscum album L. (mistletoe)
J Biol Chem, 257 (22), 13263-70
PubMed 7142144 -
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. II. Effect of pH, metabolic inhibitors, and ionophores and evidence for toxin penetration from endocytotic vesicles
J Biol Chem, 257 (13), 7504-13
PubMed 7085634 -
Entry of the toxic proteins abrin, modeccin, ricin, and diphtheria toxin into cells. I. Requirement for calcium
J Biol Chem, 257 (13), 7495-503
PubMed 6806276 -
Action of viscumin, a toxic lectin from mistletoe, on cells in culture
J Biol Chem, 257 (22), 13271-7
PubMed 7142145 -
Preparation and properties of chimeric toxins prepared from the constituent polypeptides of diphtheria toxin and ricin. Evidence for entry of ricin A-chain via the diphtheria toxin pathway
J Biol Chem, 257 (16), 9733-9
PubMed 7107588
Publications 1981
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Radioimmunoassays of abrin and ricin in blood
J Toxicol Environ Health, 8 (3), 409-17
DOI 10.1080/15287398109530079, PubMed 7345165 -
Directing toxins to cancer cells
Nature, 290 (5802), 84
DOI 10.1038/290084a0, PubMed 7207602 -
Chimeric toxins
Pharmacol Ther, 15 (3), 355-81
DOI 10.1016/0163-7258(81)90050-4, PubMed 7345440 -
Subunit structure of Shigella cytotoxin
J Biol Chem, 256 (16), 8732-8
PubMed 7021550 -
The cytotoxic activity of Shigella toxin. Evidence for catalytic inactivation of the 60 S ribosomal subunit
J Biol Chem, 256 (16), 8739-44
PubMed 6894922 -
Effects of retinoids and phorbol esters on the sensitivity of different cell lines to the polypeptide toxins modeccin, abrin, ricin and diphtheria toxin
Biochem J, 194 (3), 821-7
DOI 10.1042/bj1940821, PubMed 7306026 -
Rapid entry of nicked diphtheria toxin into cells at low pH. Characterization of the entry process and effects of low pH on the toxin molecule
J Biol Chem, 256 (17), 9068-76
PubMed 7263699
Publications 1980
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Interaction of Shigella shigae cytotoxin with receptors on sensitive and insensitive cells
J Recept Res, 1 (2), 199-213
DOI 10.3109/10799898009044098, PubMed 6895387 -
Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells
Exp Cell Res, 126 (2), 321-6
DOI 10.1016/0014-4827(80)90270-0, PubMed 7363949 -
Pathways involved in fluid phase and adsorptive endocytosis in neuroblastoma
J Cell Biol, 87 (3 Pt 1), 579-88
DOI 10.1083/jcb.87.3.579, PubMed 7462317 -
Isolation and characterization of Shigella shigae cytotoxin
J Biol Chem, 255 (1), 284-9
PubMed 7350160 -
Diphtheria toxin entry into cells is facilitated by low pH
J Cell Biol, 87 (3 Pt 1), 828-32
DOI 10.1083/jcb.87.3.828, PubMed 7462324 -
Gelonin, a new inhibitor of protein synthesis, nontoxic to intact cells. Isolation, characterization, and preparation of cytotoxic complexes with concanavalin A
J Biol Chem, 255 (14), 6947-53
PubMed 7391060 -
Human embryonal carcinoma grown in athymic mice and in vitro
Cancer Res, 40 (3), 949-53
PubMed 7471109 -
A human melanoma cell line established from xenograft in athymic mice
Br J Cancer, 41 (5), 724-33
DOI 10.1038/bjc.1980.134, PubMed 7426299 -
In vitro sensitivity of human melanoma xenografts to cytotoxic drugs. Correlation with in vivo chemosensitivity
Int J Cancer, 26 (6), 717-22
DOI 10.1002/ijc.2910260604, PubMed 7216540
Publications 1979
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Fidelity of protein synthesis in vitro is increased in the presence of spermidine
FEBS Lett, 101 (1), 93-6
DOI 10.1016/0014-5793(79)81302-2, PubMed 446744 -
Elongation-factor-2-induced sensitization of ribosomes to modeccin. Evidence for specific binding of elongation factor 2 to ribosomes in the absence of nucleotides
Eur J Biochem, 93 (3), 447-52
DOI 10.1111/j.1432-1033.1979.tb12842.x, PubMed 421687 -
Effect of temperature on the uptake, excretion and degradation of abrin and ricin by HeLa cells
Exp Cell Res, 121 (1), 15-25
DOI 10.1016/0014-4827(79)90439-7, PubMed 446525 -
Inhibitory effect of ammonium chloride and chloroquine on the entry of the toxic lectin modeccin into HeLa cells
Biochem Biophys Res Commun, 90 (2), 648-55
DOI 10.1016/0006-291x(79)91284-1, PubMed 508328
Publications 1978
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Ricin and ricinus agglutinin, toxic lectins from castor bean
Methods Enzymol, 50, 330-5
DOI 10.1016/0076-6879(78)50037-2, PubMed 661586 -
Toxic and nontoxic lectins from Abrus precatorius
Methods Enzymol, 50, 323-30
DOI 10.1016/0076-6879(78)50036-0, PubMed 661585 -
Purification and characterization of the highly toxic lectin modeccin
J Biol Chem, 253 (14), 5069-73
PubMed 97288 -
ABRIN AND RICIN-2 TOXIC LECTINS
Trends Biochem.Sci., 3 (1), 7-10 -
On the mechanism of toxin resistance in cell variants resistant to abrin and ricin
Eur J Biochem, 88 (1), 7-15
DOI 10.1111/j.1432-1033.1978.tb12417.x, PubMed 566668 -
Properties and action mechanism of the toxic lectin modeccin: interaction with cell lines resistant to modeccin, abrin, and ricin
J Supramol Struct, 9 (1), 15-25
DOI 10.1002/jss.400090103, PubMed 732310 -
[Teratocarcinoma as a model system in studies of malignancy and differentiation]
Tidsskr Nor Laegeforen, 98 (22), 998-1001
PubMed 684708 -
Interactions between abrus lectins and Sephadex particles possessing immobilized desialylated fetuin. Model studies of the interaction of lectins with cell surface receptors
Eur J Biochem, 88 (1), 307-13
DOI 10.1111/j.1432-1033.1978.tb12451.x, PubMed 78847 -
Binding, uptake and degradation of the toxic proteins abrin and ricin by toxin-resistant cell variants
Eur J Biochem, 82 (1), 13-23
DOI 10.1111/j.1432-1033.1978.tb11992.x, PubMed 620666 -
Chemical modifications of the toxic lectins abrin and ricin
Eur J Biochem, 84 (2), 323-31
DOI 10.1111/j.1432-1033.1978.tb12171.x, PubMed 639792
Publications 1977
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Studies on the accessability of ribosomes to inactivation by the toxic lectins abrin and ricin
Eur J Biochem, 74 (2), 209-15
DOI 10.1111/j.1432-1033.1977.tb11383.x, PubMed 856578 -
Inhibitory effect of abrin and ricin on the growth of transplantable murine tumors and of abrin on human cancers in nude mice
Cancer Res, 37 (12), 4559-67
PubMed 922739 -
Modeccin--a plant toxin inhibiting protein synthesis
Biochem Biophys Res Commun, 79 (4), 1176-83
DOI 10.1016/0006-291x(77)91130-5, PubMed 603653 -
Effect of abrin on peptide chain initiation
Eur J Biochem, 79 (2), 559-64
DOI 10.1111/j.1432-1033.1977.tb11840.x, PubMed 243461
Publications 1976
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Protective effect of elongation factor 2 on the inactivation of ribosomes by the toxic lectins abrin and ricin
Eur J Biochem, 64 (2), 437-43
DOI 10.1111/j.1432-1033.1976.tb10320.x, PubMed 1278169 -
Toxicity, distribution and elimination of the cancerostatic lectins abrin and ricin after parenteral injection into mice
Br J Cancer, 34 (4), 418-25
DOI 10.1038/bjc.1976.187, PubMed 974006 -
ABRIN AND RICIN - STRUCTURE AND MECHANISM OF ACTION OF 2 TOXIC LECTINS
Bull. Inst. Pasteur, 74 (1), 85-99 -
Rates of different steps involved in the inhibition of protein synthesis by the toxic lectins abrin and ricin
J Biol Chem, 251 (13), 3985-92
PubMed 932017 -
Kinetics of binding of the toxic lectins abrin and ricin to surface receptors of human cells
J Biol Chem, 251 (13), 3977-84
PubMed 6468
Publications 1975
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On the mechanism of protein-synthesis inhibition by abrin and ricin. Inhibition of the GTP-hydrolysis site on the 60-S ribosomal subunit
Eur J Biochem, 59 (2), 573-80
DOI 10.1111/j.1432-1033.1975.tb02484.x, PubMed 128455 -
Stimulation of human lymphocytes by galactose-specific abrus and ricinus lectins
J Immunol, 115 (4), 1045-8
PubMed 1176765 -
INTERACTIONS BETWEEN RICINUS AGGLUTININ AND HUMAN PLASMA-PROTEINS
Scand. J. Immunol. (2), 125-134 -
Cleavage of adenovirus-5 DNA by an endonuclease from Haemophilus parainfluenzae
FEBS Lett, 57 (2), 153-7
DOI 10.1016/0014-5793(75)80705-8, PubMed 1175785 -
Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains
Eur J Biochem, 60 (1), 281-8
DOI 10.1111/j.1432-1033.1975.tb21001.x, PubMed 1204642 -
Studies on the structure and properties of the lectins from Abrus precatorius and Ricinus communis
Biochim Biophys Acta, 405 (1), 1-10
DOI 10.1016/0005-2795(75)90308-6, PubMed 1174560 -
Conformation-dependent antigenic determinants in the toxic lectin ricin
J Immunol, 114 (6), 1743-8
PubMed 47877 -
Interactions between ricinus agglutinin and human IgM and IgG
Scand J Immunol, 4 (3), 287-94
DOI 10.1111/j.1365-3083.1975.tb02628.x, PubMed 1080291
Publications 1974
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Lectins from Abrus precatorius and Ricinus communis. II. Hybrid toxins and their interaction with chain-specific antibodies
J Immunol, 113 (3), 842-7
PubMed 4414071 -
Clinical significance of estrogen receptors in human breast cancer
Biomedicine, 20 (6), 377-83
PubMed 4376029 -
Mechanism of action of the toxic lectins abrin and ricin
Nature, 249 (458), 627-31
DOI 10.1038/249627a0, PubMed 4857870 -
Isolation and comparison of galactose-binding lectins from Abrus precatorius and Ricinus communis
J Biol Chem, 249 (3), 803-10
PubMed 4811904 -
Lectins from Abrus precatorius and Ricinus communis. I. Immunochemical relationships between toxins and agglutinins
J Immunol, 113 (3), 835-41
PubMed 4213214 -
On the toxic proteins abrin and ricin. Studies of their binding to and entry into Ehrlich ascites cells
J Biol Chem, 249 (11), 3557-62
PubMed 4208663 -
TOXIC PROTEINS ABRIN AND RICIN - STUDIES OF THEIR BINDING TO AND ENTRY INTO EHRLICH ASCITES-CELLS
J. Biol. Chem., 249 (11), 3557-3562
Publications 1973
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[Diphtheria toxin--a specific inhibitor of protein synthesis]
Tidsskr Nor Laegeforen, 93 (4), 223-7
PubMed 4691026 -
[Gene activation and mRNA synthesis in higher organisms]
Tidsskr Nor Laegeforen, 93 (16), 1230-5
PubMed 4356591 -
Inactivation of eucaryotic ribosomes by the toxic plant proteins abrin and ricin
Mol Biol Rep, 1 (1), 15-20
DOI 10.1007/BF00357400, PubMed 24197425 -
Different biological properties of the two constituent peptide chains of ricin, a toxic protein inhibiting protein synthesis
Biochemistry, 12 (16), 3121-6
DOI 10.1021/bi00740a028, PubMed 4730499 -
Isolation and properties of abrin: a toxic protein inhibiting protein synthesis. Evidence for different biological functions of its two constituent-peptide chains
Eur J Biochem, 35 (1), 179-85
DOI 10.1111/j.1432-1033.1973.tb02823.x, PubMed 4123356 -
Content of estrogen receptors in human breast cancer
Eur J Cancer, 9 (5), 353-7
DOI 10.1016/0014-2964(73)90050-9, PubMed 4355726
Publications 1972
-
[Iridocyclitis with juvenile rheumatoid arthritis]
Tidsskr Nor Laegeforen, 12 (13), 922-3
PubMed 5063957 -
Binding of rat liver ribosomes to nuclear complementary RNA
Biochim Biophys Acta, 281 (2), 270-6
DOI 10.1016/0005-2787(72)90179-7, PubMed 4629425 -
Antigenic difference between informofers and protein bound to polyribosomal mRNA from rat liver
Nat New Biol, 240 (98), 90-2
DOI 10.1038/newbio240090a0, PubMed 4117892 -
Toxic proteins inhibiting protein synthesis
Naturwissenschaften, 59 (11), 497-502
DOI 10.1007/BF00609814, PubMed 4657651 -
Deoxycholate-induced release of monosomes from rat liver polyribosomes
Biochim Biophys Acta, 272 (1), 75-80
DOI 10.1016/0005-2787(72)90035-4, PubMed 5043716 -
Ricin - a potent inhibitor of protein synthesis
FEBS Lett, 20 (3), 327-329
DOI 10.1016/0014-5793(72)80098-x, PubMed 11946449 -
Inhibition of peptide chain elongation
Nature, 238 (5365), 459-61
DOI 10.1038/238459a0, PubMed 4561855 -
Treatment of abrin and ricin with -mercaptoethanol opposite effects on their toxicity in mice and their ability to inhibit protein synthesis in a cell-free system
FEBS Lett, 28 (1), 48-50
DOI 10.1016/0014-5793(72)80674-4, PubMed 4646874 -
Possible function of the protein bound to nuclear complementary RNA
FEBS Lett, 20 (2), 181-183
DOI 10.1016/0014-5793(72)80788-9, PubMed 11946410 -
Protein synthesis in the presence of non-ionic detergents in a cell-free system from rabbit reticulocytes
Biochem J, 130 (1), 297-9
DOI 10.1042/bj1300297, PubMed 4655435 -
Translation of mouse globin mRNA by isolated ribosomal subunits from rabbit reticulocytes
Biochim Biophys Acta, 272 (4), 663-6
DOI 10.1016/0005-2787(72)90525-4, PubMed 5050924
Publications 1971
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Characterization of the complex containing rapidly labelled RNA in EDTA-treated polyribosomes from rat liver
Eur J Biochem, 18 (2), 242-51
DOI 10.1111/j.1432-1033.1971.tb01237.x, PubMed 5541508 -
The isolation of polysomes from rat liver. Contamination by membrane proteins with high affinity to ribosomes
Biochim Biophys Acta, 232 (4), 705-16
PubMed 5556851 -
Evidence that protein is bound to the rapidly labelled RNA in polyribosomes in vivo
Eur J Biochem, 23 (2), 248-52
DOI 10.1111/j.1432-1033.1971.tb01615.x, PubMed 5003205 -
Further studies on the protein bound to the messenger RNA in mammalian polysomes
Eur J Biochem, 23 (3), 557-63
DOI 10.1111/j.1432-1033.1971.tb01654.x, PubMed 5003111
Publications 1970
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The isolation of polysomes from rat liver. Contamination of polysomes by ribonucleoprotein of nuclear origin
Biochim Biophys Acta, 213 (1), 149-58
DOI 10.1016/0005-2787(70)90016-x, PubMed 4992322 -
Removal of structural proteins from ribosomes by treatment with sodium deoxycholate in the presence of EDTA
FEBS Lett, 7 (3), 211-213
DOI 10.1016/0014-5793(70)80162-4, PubMed 11947473 -
Characterization of protein bound to rapidly-labelled RNA in polyribosomes from rat liver
Eur J Biochem, 15 (3), 464-71
DOI 10.1111/j.1432-1033.1970.tb01029.x, PubMed 4989503
Publications 1968
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Amino acid control of RNA synthesis in T4-infected Escherichia coli
Eur J Biochem, 7 (1), 128-36
DOI 10.1111/j.1432-1033.1968.tb19583.x, PubMed 4884582