Pål Møller
- Senior scientist; MD, PhD
Publications 2024
Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations
JAMA Oncol, 10 (4), 484-492
DOI 10.1001/jamaoncol.2023.6937, PubMed 38421677
Incidence of endometrial cancer in BRCA mutation carriers
Gynecol Oncol, 189, 148-155
DOI 10.1016/j.ygyno.2024.07.687, PubMed 39173195
MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations
JAMA Oncol, 10 (4), 493-499
DOI 10.1001/jamaoncol.2023.6944, PubMed 38421676
Incidences of colorectal adenomas and cancers under colonoscopy surveillance suggest an accelerated "Big Bang" pathway to CRC in three of the four Lynch syndromes
Hered Cancer Clin Pract, 22 (1), 6
DOI 10.1186/s13053-024-00279-3, PubMed 38741120
Commentary on Estimating cancer risk in carriers of Lynch syndrome variants in UK Biobank
J Med Genet (in press)
DOI 10.1136/jmg-2024-110385, PubMed 39375027
Incidence of Peritoneal Cancer Following Oophorectomy among BRCA1 and BRCA2 Mutation Carriers
J Natl Cancer Inst (in press)
DOI 10.1093/jnci/djae151, PubMed 38937272
Delineating genotype and parent-of-origin effect on the phenotype in MSH6-associated Lynch syndrome
Genes Chromosomes Cancer, 63 (5), e23237
DOI 10.1002/gcc.23237, PubMed 38722212
Publications 2023
A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
Cancers (Basel), 15 (16)
DOI 10.3390/cancers15164124, PubMed 37627152
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
EClinicalMedicine, 58, 101909
DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409
Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis
Br J Cancer, 130 (2), 269-274
DOI 10.1038/s41416-023-02503-8, PubMed 38030749
Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
Hered Cancer Clin Pract, 21 (1), 19
DOI 10.1186/s13053-023-00263-3, PubMed 37821984
Publications 2022
Is HLA type a possible cancer risk modifier in Lynch syndrome?
Int J Cancer, 152 (10), 2024-2031
DOI 10.1002/ijc.34312, PubMed 36214792
Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
Clin Gastroenterol Hepatol, 21 (3), 581-603.e33
DOI 10.1016/j.cgh.2022.12.006, PubMed 36549470
Response to Chambuso et al
Genet Med, 24 (5), 1151
DOI 10.1016/j.gim.2022.01.005, PubMed 35216900
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
Genet Med, 24 (10), 2208
DOI 10.1016/j.gim.2022.08.005, PubMed 36205748
The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
Cancer, 129 (6), 901-907
DOI 10.1002/cncr.34615, PubMed 36571512
The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
Hered Cancer Clin Pract, 20 (1), 37
DOI 10.1186/s13053-022-00243-z, PubMed 36411472
Inherited Cancer Genetic Epidemiology to Improve Precision Medicine
J Clin Med, 11 (3)
DOI 10.3390/jcm11030879, PubMed 35160330
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
Hered Cancer Clin Pract, 20 (1), 36
DOI 10.1186/s13053-022-00241-1, PubMed 36182917
Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach
Hum Mutat, 43 (12), 1921-1944
DOI 10.1002/humu.24449, PubMed 35979650
Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
Gynecol Oncol, 164 (3), 514-521
DOI 10.1016/j.ygyno.2022.01.014, PubMed 35063280
Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
Cancers (Basel), 14 (22)
DOI 10.3390/cancers14225603, PubMed 36428697
Publications 2021
No Difference in Penetrance between Truncating and Missense/Aberrant Splicing Pathogenic Variants in MLH1 and MSH2: A Prospective Lynch Syndrome Database Study
J Clin Med, 10 (13)
DOI 10.3390/jcm10132856, PubMed 34203177
Weight Gain and the Risk of Ovarian Cancer in BRCA1 and BRCA2 Mutation Carriers
Cancer Epidemiol Biomarkers Prev, 30 (11), 2038-2043
DOI 10.1158/1055-9965.EPI-21-0296, PubMed 34426412
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
Genet Med, 24 (1), 119-129
DOI 10.1016/j.gim.2021.08.016, PubMed 34906479
Towards evidence-based personalised precision medicine for Lynch syndrome
Lancet Oncol., 22 (9), E383
Correction to: Letter to the Editor-Recent advances in Lynch syndrome
Fam Cancer, 20 (2), 119
DOI 10.1007/s10689-021-00246-0, PubMed 33792829
Towards evidence-based personalised precision medicine for Lynch syndrome
Lancet Oncol, 22 (9), e383
DOI 10.1016/S1470-2045(21)00400-9, PubMed 34478667
Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer
Int J Cancer, 149 (11), 1955-1960
DOI 10.1002/ijc.33749, PubMed 34310709
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Eur J Cancer, 148, 124-133
DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481
Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers
Breast Cancer Res Treat, 187 (2), 515-523
DOI 10.1007/s10549-020-06072-9, PubMed 33423179
Publications 2020
The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance
Int J Cancer, 148 (4), 800-811
DOI 10.1002/ijc.33224, PubMed 32683684
Spectrum and Frequency of Tumors, Cancer Risk and Survival in Chilean Families with Lynch Syndrome: Experience of the Implementation of a Registry
J Clin Med, 9 (6)
DOI 10.3390/jcm9061861, PubMed 32549215
Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Genet Med, 23 (4), 705-712
DOI 10.1038/s41436-020-01029-1, PubMed 33257847
Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum
Int J Cancer, 148 (2), 512-513
DOI 10.1002/ijc.33214, PubMed 32783184
Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Genet Med, 22 (9), 1569
DOI 10.1038/s41436-020-0892-4, PubMed 32690931
Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database
J Clin Med, 9 (7)
DOI 10.3390/jcm9072290, PubMed 32708519
Long-term outcomes following a diagnosis of ovarian cancer at the time of preventive oophorectomy among BRCA1 and BRCA2 mutation carriers
Int J Gynecol Cancer, 30 (6), 825-830
DOI 10.1136/ijgc-2019-001141, PubMed 32354794
The Prospective Lynch Syndrome Database reports enable evidence-based personal precision health care
Hered Cancer Clin Pract, 18, 6
DOI 10.1186/s13053-020-0138-0, PubMed 32190163
Correction: Møller, P.; et al. Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift. Cancers 2019, 11, 132
Cancers (Basel), 12 (2)
DOI 10.3390/cancers12020410, PubMed 32050665
Letter to the Editor-Recent advances in Lynch syndrome
Fam Cancer, 20 (2), 117-118
DOI 10.1007/s10689-020-00200-6, PubMed 32770425
MLH1 intronic variants mapping to + 5 position of splice donor sites lead to deleterious effects on RNA splicing
Fam Cancer, 19 (4), 323-336
DOI 10.1007/s10689-020-00182-5, PubMed 32363481
Prospective observational data informs understanding and future management of Lynch syndrome: insights from the Prospective Lynch Syndrome Database (PLSD)
Fam Cancer, 20 (1), 35-39
DOI 10.1007/s10689-020-00193-2, PubMed 32507935
Publications 2019
The Manchester International Consensus Group recommendations for the management of gynecological cancers in Lynch syndrome
Genet Med, 21 (10), 2390-2400
DOI 10.1038/s41436-019-0489-y, PubMed 30918358
A snapshot of current genetic testing practice in Lynch syndrome: The results of a representative survey of 33 Latin American existing centres/registries
Eur J Cancer, 119, 112-121
DOI 10.1016/j.ejca.2019.07.017, PubMed 31442815
Results of multigene panel testing in familial cancer cases without genetic cause demonstrated by single gene testing
Sci Rep, 9 (1), 18555
DOI 10.1038/s41598-019-54517-z, PubMed 31811167
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Genet Med, 22 (1), 15-25
DOI 10.1038/s41436-019-0596-9, PubMed 31337882
Survival by colon cancer stage and screening interval in Lynch syndrome: a prospective Lynch syndrome database report
Hered Cancer Clin Pract, 17, 28
DOI 10.1186/s13053-019-0127-3, PubMed 31636762
Oophorectomy and risk of contralateral breast cancer among BRCA1 and BRCA2 mutation carriers
Breast Cancer Res Treat, 175 (2), 443-449
DOI 10.1007/s10549-019-05162-7, PubMed 30756284
International trends in the uptake of cancer risk reduction strategies in women with a BRCA1 or BRCA2 mutation
Br J Cancer, 121 (1), 15-21
DOI 10.1038/s41416-019-0446-1, PubMed 30971774
Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift
Cancers (Basel), 11 (2)
DOI 10.3390/cancers11020132, PubMed 30678073
Response to Tolva et al
Genet Med, 22 (4), 813-814
DOI 10.1038/s41436-019-0717-5, PubMed 31801985
Lack of association between screening interval and cancer stage in Lynch syndrome may be accounted for by over-diagnosis; a prospective Lynch syndrome database report
Hered Cancer Clin Pract, 17, 8
DOI 10.1186/s13053-019-0106-8, PubMed 30858900
The Apparent Genetic Anticipation in PMS2-Associated Lynch Syndrome Families Is Explained by Birth-cohort Effect
Cancer Epidemiol Biomarkers Prev, 28 (6), 1010-1014
DOI 10.1158/1055-9965.EPI-18-0576, PubMed 30824524
Publications 2018
Genetic variants of prospectively demonstrated phenocopies in BRCA1/2 kindreds
Hered Cancer Clin Pract, 16, 4
DOI 10.1186/s13053-018-0086-0, PubMed 29371908
Potentially pathogenic germline CHEK2 c.319+2T>A among multiple early-onset cancer families
Fam Cancer, 17 (1), 141-153
DOI 10.1007/s10689-017-0011-0, PubMed 28608266
Identification of genetic variants for clinical management of familial colorectal tumors
BMC Med Genet, 19 (1), 26
DOI 10.1186/s12881-018-0533-9, PubMed 29458332
Ancient genomes from Iceland reveal the making of a human population
Science, 360 (6392), 1028-1032
DOI 10.1126/science.aar2625, PubMed 29853688
Prospective evaluation of body size and breast cancer risk among BRCA1 and BRCA2 mutation carriers
Int J Epidemiol, 47 (3), 987-997
DOI 10.1093/ije/dyy039, PubMed 29547931
Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation
Gynecol Oncol, 150 (1), 85-91
DOI 10.1016/j.ygyno.2018.05.011, PubMed 29793803
Hormone Replacement Therapy After Oophorectomy and Breast Cancer Risk Among BRCA1 Mutation Carriers
JAMA Oncol, 4 (8), 1059-1065
DOI 10.1001/jamaoncol.2018.0211, PubMed 29710224
Our genes, our selves: hereditary breast cancer and biological citizenship in Norway
Med Health Care Philos, 21 (2), 239-242
DOI 10.1007/s11019-017-9803-0, PubMed 28939999
Retraction Note to: The BRCA2 variant c.68-7 T > A is associated with breast cancer
Hered Cancer Clin Pract, 16, 10
DOI 10.1186/s13053-018-0093-1, PubMed 29745381
Cancer Risks for PMS2-Associated Lynch Syndrome
J Clin Oncol, 36 (29), 2961-2968
DOI 10.1200/JCO.2018.78.4777, PubMed 30161022
From colorectal cancer pattern to the characterization of individuals at risk: Picture for genetic research in Latin America
Int J Cancer, 145 (2), 318-326
DOI 10.1002/ijc.31920, PubMed 30303536
Publications 2017
The BRCA2 variant c.68-7 T>A is associated with breast cancer
Hered Cancer Clin Pract, 15, 20 (Retracted)
DOI 10.1186/s13053-017-0080-y, PubMed 29158857
Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
Gut, 67 (7), 1306-1316
DOI 10.1136/gutjnl-2017-314057, PubMed 28754778
A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America
BMC Cancer, 17 (1), 623
DOI 10.1186/s12885-017-3599-4, PubMed 28874130
Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report
Hered Cancer Clin Pract, 15, 18
DOI 10.1186/s13053-017-0078-5, PubMed 29046738
Publications 2016
Hormone replacement therapy after menopause and risk of breast cancer in BRCA1 mutation carriers: a case-control study
Breast Cancer Res Treat, 155 (2), 365-73
DOI 10.1007/s10549-016-3685-3, PubMed 26780555
Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers
J Natl Cancer Inst, 109 (1)
DOI 10.1093/jnci/djw177, PubMed 27601060
Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
Gut, 66 (9), 1657-1664
DOI 10.1136/gutjnl-2016-311403, PubMed 27261338
Publications 2015
Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
Fertil Steril, 105 (3), 781-785
DOI 10.1016/j.fertnstert.2015.11.034, PubMed 26698676
Ten modifiers of BRCA1 penetrance validated in a Norwegian series
Hered Cancer Clin Pract, 13 (1), 14
DOI 10.1186/s13053-015-0035-0, PubMed 26052370
Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
Gut, 66 (3), 464-472
DOI 10.1136/gutjnl-2015-309675, PubMed 26657901
Tumour characteristics and survival in familial breast cancer prospectively diagnosed by annual mammography
Breast Cancer Res Treat, 152 (1), 87-94
DOI 10.1007/s10549-015-3448-6, PubMed 26037256
Risk factors for endometrial cancer among women with a BRCA1 or BRCA2 mutation: a case control study
Fam Cancer, 14 (3), 383-91
DOI 10.1007/s10689-015-9798-8, PubMed 25838159
The effect of genotypes and parent of origin on cancer risk and age of cancer development in PMS2 mutation carriers
Genet Med, 18 (4), 405-9
DOI 10.1038/gim.2015.83, PubMed 26110232
Involvement of MBD4 inactivation in mismatch repair-deficient tumorigenesis
Oncotarget, 6 (40), 42892-904
DOI 10.18632/oncotarget.5740, PubMed 26503472
Publications 2014
Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation
J Clin Oncol, 32 (15), 1547-53
DOI 10.1200/JCO.2013.53.2820, PubMed 24567435
Mammography screening and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a prospective study
Breast Cancer Res Treat, 147 (1), 113-8
DOI 10.1007/s10549-014-3063-y, PubMed 25082516
The Norwegian PMS2 founder mutation c.989-1G > T shows high penetrance of microsatellite instable cancers with normal immunohistochemistry
Hered Cancer Clin Pract, 12 (1), 12
DOI 10.1186/1897-4287-12-12, PubMed 24790682
Duration of tamoxifen use and the risk of contralateral breast cancer in BRCA1 and BRCA2 mutation carriers
Breast Cancer Res Treat, 146 (2), 421-7
DOI 10.1007/s10549-014-3026-3, PubMed 24951267
Factors influencing ovulation and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers
Int J Cancer, 137 (5), 1136-46
DOI 10.1002/ijc.29386, PubMed 25482078
Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers
Breast Cancer Res Treat, 143 (3), 579-86
DOI 10.1007/s10549-013-2823-4, PubMed 24458845
The clinical utility of genetic testing in breast cancer kindreds: a prospective study in families without a demonstrable BRCA mutation
Breast Cancer Res Treat, 144 (3), 607-14
DOI 10.1007/s10549-014-2902-1, PubMed 24619173
Cancer risk and genotype-phenotype correlations in PTEN hamartoma tumor syndrome
Fam Cancer, 13 (1), 57-63
DOI 10.1007/s10689-013-9674-3, PubMed 23934601
Lynch syndrome caused by germline PMS2 mutations: delineating the cancer risk
J Clin Oncol, 33 (4), 319-25
DOI 10.1200/JCO.2014.57.8088, PubMed 25512458
MRI screening of women with hereditary predisposition to breast cancer: diagnostic performance and survival analysis
Breast Cancer Res Treat, 148 (3), 687-8
DOI 10.1007/s10549-014-3178-1, PubMed 25398653
Publications 2013
Risk reducing mastectomy, breast reconstruction and patient satisfaction in Norwegian BRCA1/2 mutation carriers
Breast, 23 (1), 38-43
DOI 10.1016/j.breast.2013.10.002, PubMed 24210736
[Sperm mutations and older fathers]
Tidsskr Nor Laegeforen, 133 (6), 609
DOI 10.4045/tidsskr.13.0253, PubMed 23552137
Survival of patients with BRCA1-associated breast cancer diagnosed in an MRI-based surveillance program
Breast Cancer Res Treat, 139 (1), 155-61
DOI 10.1007/s10549-013-2540-z, PubMed 23615785
The incidence of endometrial cancer in women with BRCA1 and BRCA2 mutations: an international prospective cohort study
Gynecol Oncol, 130 (1), 127-31
DOI 10.1016/j.ygyno.2013.03.027, PubMed 23562522
Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database
Nat Genet, 46 (2), 107-115
DOI 10.1038/ng.2854, PubMed 24362816
The impact of pregnancy on breast cancer survival in women who carry a BRCA1 or BRCA2 mutation
Breast Cancer Res Treat, 142 (1), 177-85
DOI 10.1007/s10549-013-2729-1, PubMed 24136669
Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts
Gut, 62 (6), 812-23
DOI 10.1136/gutjnl-2012-304356, PubMed 23408351
Publications 2012
Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families
BMC Med Genet, 13, 46
DOI 10.1186/1471-2350-13-46, PubMed 22712434
Is colorectal surveillance indicated in patients with PTEN mutations?
Colorectal Dis, 14 (9), e562-6
DOI 10.1111/j.1463-1318.2012.03121.x, PubMed 22672595
Combined analysis of three Lynch syndrome cohorts confirms the modifying effects of 8q23.3 and 11q23.1 in MLH1 mutation carriers
Int J Cancer, 132 (7), 1556-64
DOI 10.1002/ijc.27843, PubMed 22987364
HOXB13 is a susceptibility gene for prostate cancer: results from the International Consortium for Prostate Cancer Genetics (ICPCG)
Hum Genet, 132 (1), 5-14
DOI 10.1007/s00439-012-1229-4, PubMed 23064873
Publications 2011
Deciphering the colon cancer genes--report of the InSiGHT-Human Variome Project Workshop, UNESCO, Paris 2010
Hum Mutat, 32 (4), 491-4
DOI 10.1002/humu.21450, PubMed 21387463
Chromosomes 4 and 8 implicated in a genome wide SNP linkage scan of 762 prostate cancer families collected by the ICPCG
Prostate, 72 (4), 410-26
DOI 10.1002/pros.21443, PubMed 21748754
CGEN--a Clinical GENetics software application
Hum Mutat, 32 (5), 537-42
DOI 10.1002/humu.21452, PubMed 21387464
A SImplified method for Segregation Analysis (SISA) to determine penetrance and expression of a genetic variant in a family
Hum Mutat, 32 (5), 568-71
DOI 10.1002/humu.21441, PubMed 21309035
Publications 2010
Genome-wide search for breast cancer linkage in large Icelandic non-BRCA1/2 families
Breast Cancer Res, 12 (4), R50
DOI 10.1186/bcr2608, PubMed 20637093
Fanconi anaemia, BRCA2 and familial considerations - follow up on a previous case report
Acta Paediatr, 99 (11), 1741-3
DOI 10.1111/j.1651-2227.2010.01929.x, PubMed 20608899
Genome-wide linkage analysis of 1,233 prostate cancer pedigrees from the International Consortium for Prostate Cancer Genetics using novel sumLINK and sumLOD analyses
Prostate, 70 (7), 735-44
DOI 10.1002/pros.21106, PubMed 20333727
Alcohol consumption and the risk of breast cancer among BRCA1 and BRCA2 mutation carriers
Breast, 19 (6), 479-83
DOI 10.1016/j.breast.2010.05.009, PubMed 20541936
High penetrances of BRCA1 and BRCA2 mutations confirmed in a prospective series
Hered Cancer Clin Pract, 8 (1), 2
DOI 10.1186/1897-4287-8-2, PubMed 20180971
Current clinical criteria for Lynch syndrome are not sensitive enough to identify MSH6 mutation carriers
J Med Genet, 47 (9), 579-85
DOI 10.1136/jmg.2010.077677, PubMed 20587412
Publications 2009
Germ-line mutations in mismatch repair genes associated with prostate cancer
Cancer Epidemiol Biomarkers Prev, 18 (9), 2460-7
DOI 10.1158/1055-9965.EPI-09-0058, PubMed 19723918
Survival in women with MMR mutations and ovarian cancer: a multicentre study in Lynch syndrome kindreds
J Med Genet, 47 (2), 99-102
DOI 10.1136/jmg.2009.068130, PubMed 19635727
Survival in Norwegian BRCA1 mutation carriers with breast cancer
Hered Cancer Clin Pract, 7 (1), 7
DOI 10.1186/1897-4287-7-7, PubMed 19366445
Publications 2008
Hormone therapy and the risk of breast cancer in BRCA1 mutation carriers
J Natl Cancer Inst, 100 (19), 1361-7
DOI 10.1093/jnci/djn313, PubMed 18812548
Smoking and the risk of breast cancer in BRCA1 and BRCA2 carriers: an update
Breast Cancer Res Treat, 114 (1), 127-35
DOI 10.1007/s10549-008-9977-5, PubMed 18483851
High risk of endometrial cancer in colorectal cancer kindred is pathognomonic for MMR-mutation carriers
Fam Cancer, 8 (2), 145-51
DOI 10.1007/s10689-008-9219-3, PubMed 18841495
Infertility, treatment of infertility, and the risk of breast cancer among women with BRCA1 and BRCA2 mutations: a case-control study
Cancer Causes Control, 19 (10), 1111-9
DOI 10.1007/s10552-008-9175-0, PubMed 18509731
High risk for ovarian cancer in a prospective series is restricted to BRCA1/2 mutation carriers
Clin Cancer Res, 14 (22), 7569-73
DOI 10.1158/1078-0432.CCR-08-0112, PubMed 19010876
International variation in rates of uptake of preventive options in BRCA1 and BRCA2 mutation carriers
Int J Cancer, 122 (9), 2017-22
DOI 10.1002/ijc.23340, PubMed 18196574
Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group
J Clin Oncol, 26 (7), 1093-7
DOI 10.1200/JCO.2007.12.6078, PubMed 18195327
Prophylactic bilateral salpingo-oophorectomy (PBSO) with or without prophylactic bilateral mastectomy (PBM) or no intervention in BRCA1 mutation carriers: a cost-effectiveness analysis
Eur J Cancer, 44 (7), 963-71
DOI 10.1016/j.ejca.2008.02.025, PubMed 18362067
Psychological and cancer-specific distress at 18 months post-testing in women with demonstrated BRCA1 mutations for hereditary breast/ovarian cancer
Fam Cancer, 7 (3), 245-54
DOI 10.1007/s10689-008-9182-z, PubMed 18219587
Guidelines for the clinical management of familial adenomatous polyposis (FAP)
Gut, 57 (5), 704-13
DOI 10.1136/gut.2007.136127, PubMed 18194984
Publications 2007
Compelling evidence for a prostate cancer gene at 22q12.3 by the International Consortium for Prostate Cancer Genetics
Hum Mol Genet, 16 (11), 1271-8
DOI 10.1093/hmg/ddm075, PubMed 17478474
Discussion on the use of taxanes for treatment of breast cancers in BRCA1 mutations carriers
Hered. Cancer Clin. Pract., 5 (3), 119-143
Amplification of TOP2A and HER-2 genes in breast cancers occurring in patients harbouring BRCA1 germline mutations
Acta Oncol, 46 (2), 199-203
DOI 10.1080/02841860600949552, PubMed 17453369
Sensitivity of MRI versus conventional screening in the diagnosis of BRCA-associated breast cancer in a national prospective series
Breast, 16 (4), 367-74
DOI 10.1016/j.breast.2007.01.006, PubMed 17317184
Age at first birth and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
Breast Cancer Res Treat, 105 (2), 221-8
DOI 10.1007/s10549-006-9441-3, PubMed 17245541
Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study
Lancet Oncol, 8 (1), 26-34
DOI 10.1016/S1470-2045(06)70983-4, PubMed 17196508
Surveillance for familial breast cancer: Differences in outcome according to BRCA mutation status
Int J Cancer, 121 (5), 1017-20
DOI 10.1002/ijc.22789, PubMed 17471561
Genetic epidemiology of BRCA mutations--family history detects less than 50% of the mutation carriers
Eur J Cancer, 43 (11), 1713-7
DOI 10.1016/j.ejca.2007.04.023, PubMed 17574839
No sib pair concordance for breast or ovarian cancer in BRCA1 mutation carriers
Hered Cancer Clin Pract, 5 (2), 67-71
DOI 10.1186/1897-4287-5-2-67, PubMed 19725986
Prevention of colorectal cancer by colonoscopic surveillance in families with hereditary colorectal cancer
Scand J Gastroenterol, 42 (5), 611-7
DOI 10.1080/00365520601010230, PubMed 17454882
Publications 2006
The risk of endometrial cancer in women with BRCA1 and BRCA2 mutations. A prospective study
Gynecol Oncol, 104 (1), 7-10
DOI 10.1016/j.ygyno.2006.08.004, PubMed 16962648
Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation
JAMA, 296 (2), 185-92
DOI 10.1001/jama.296.2.185, PubMed 16835424
Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers
Breast Cancer Res, 8 (2), R15
DOI 10.1186/bcr1387, PubMed 16563180
Quality of life and its relation to cancer-related stress in women of families with hereditary cancer without demonstrated mutation
Qual Life Res, 15 (3), 461-70
DOI 10.1007/s11136-005-3008-3, PubMed 16547785
[Increased incidence of testicular dysgenesis?]
Tidsskr Nor Laegeforen, 126 (20), 2688; author reply 2688
PubMed 17057775
[Handling of hereditary intestinal cancer]
Tidsskr Nor Laegeforen, 126 (15), 1937-9
PubMed 16915319
Screening mammography and risk of breast cancer in BRCA1 and BRCA2 mutation carriers: a case-control study
Lancet Oncol, 7 (5), 402-6
DOI 10.1016/S1470-2045(06)70624-6, PubMed 16648044
The frequent BRCA1 mutation 1135insA has multiple origins: a haplotype study in different populations
BMC Med Genet, 7, 15
DOI 10.1186/1471-2350-7-15, PubMed 16509964
Germline PTEN mutations are rare and highly penetrant
Hered Cancer Clin Pract, 4 (4), 177-85
DOI 10.1186/1897-4287-4-4-177, PubMed 20223021
Pooled genome linkage scan of aggressive prostate cancer: results from the International Consortium for Prostate Cancer Genetics
Hum Genet, 120 (4), 471-85
DOI 10.1007/s00439-006-0219-9, PubMed 16932970
MUTYH Mutations Do Not Cause HNPCC or Late Onset Familial Colorectal Cancer
Hered Cancer Clin Pract, 4 (2), 90-3
DOI 10.1186/1897-4287-4-2-90, PubMed 20223013
Estimated prevalence of hereditary cancers and the need for surveillance in a Norwegian county, Telemark
Scand J Gastroenterol, 41 (1), 71-9
DOI 10.1080/00365520510023891, PubMed 16373279
Publications 2005
Effect of pregnancy as a risk factor for breast cancer in BRCA1/BRCA2 mutation carriers
Int J Cancer, 117 (6), 988-91
DOI 10.1002/ijc.21273, PubMed 15986445
Breast cancer risk following bilateral oophorectomy in BRCA1 and BRCA2 mutation carriers: an international case-control study
J Clin Oncol, 23 (30), 7491-6
DOI 10.1200/JCO.2004.00.7138, PubMed 16234515
Psychological distress in women at risk of hereditary breast/ovarian or HNPCC cancers in the absence of demonstrated mutations
Fam Cancer, 4 (2), 121-6
DOI 10.1007/s10689-004-7995-y, PubMed 15951962
Macrophage scavenger receptor 1 999C>T (R293X) mutation and risk of prostate cancer
Cancer Epidemiol Biomarkers Prev, 14 (2), 397-402
DOI 10.1158/1055-9965.EPI-04-0202, PubMed 15734964
Hormone replacement therapy and the risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers
Gynecol Oncol, 100 (1), 83-8
DOI 10.1016/j.ygyno.2005.07.110, PubMed 16137751
[Screening for hereditary hemochromatosis?]
Tidsskr Nor Laegeforen, 125 (8), 1044-5; author reply 1045
PubMed 15852086
[Hereditary breast cancer]
Tidsskr Nor Laegeforen, 125 (22), 3136-8
PubMed 16299574
Immunohistochemistry identifies carriers of mismatch repair gene defects causing hereditary nonpolyposis colorectal cancer
J Clin Oncol, 23 (21), 4705-12
DOI 10.1200/JCO.2005.05.180, PubMed 16034045
Molecular characterization of the spectrum of genomic deletions in the mismatch repair genes MSH2, MLH1, MSH6, and PMS2 responsible for hereditary nonpolyposis colorectal cancer (HNPCC)
Genes Chromosomes Cancer, 44 (2), 123-38
DOI 10.1002/gcc.20219, PubMed 15942939
A comparison of bilateral breast cancers in BRCA carriers
Cancer Epidemiol Biomarkers Prev, 14 (6), 1534-8
DOI 10.1158/1055-9965.EPI-05-0070, PubMed 15941968
A combined genomewide linkage scan of 1,233 families for prostate cancer-susceptibility genes conducted by the international consortium for prostate cancer genetics
Am J Hum Genet, 77 (2), 219-29
DOI 10.1086/432377, PubMed 15988677
Publications 2004
Cancer risk in hereditary nonpolyposis colorectal cancer due to MSH6 mutations: impact on counseling and surveillance
Gastroenterology, 127 (1), 17-25
DOI 10.1053/j.gastro.2004.03.068, PubMed 15236168
Towards evidence-based management of inherited breast and breast-ovarian cancer
Hered Cancer Clin Pract, 2 (1), 11-6
DOI 10.1186/1897-4287-2-1-11, PubMed 20233478
[Retinoblastoma--hereditary eye cancer in children?]
Tidsskr Nor Laegeforen, 124 (6), 830; author reply 830
PubMed 15039827
BRCA1 testing with definitive results: a prospective study of psychological distress in a large clinic-based sample
Fam Cancer, 3 (1), 21-8
DOI 10.1023/B:FAME.0000026820.32469.4a, PubMed 15131402
Publications 2003
Uptake of BRCA1 genetic testing in adult sisters and daughters of known mutation carriers in Norway
J Genet Couns, 12 (5), 405-17
DOI 10.1023/a:1025864703405, PubMed 14758817
EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer
Cancer Res, 63 (1), 154-8
PubMed 12517792
The inframe MSH2 codon 596 deletion is linked with HNPCC and associated with lack of MSH2 protein in tumours
Fam Cancer, 2 (1), 9-13
DOI 10.1023/a:1023362205205, PubMed 14574162
Publications 2002
Oral contraceptives and risk of familial breast cancer
Cancer Detect Prev, 26 (1), 23-7
DOI 10.1016/s0361-090x(02)00004-1, PubMed 12088199
Survival in prospectively ascertained familial breast cancer: analysis of a series stratified by tumour characteristics, BRCA mutations and oophorectomy
Int J Cancer, 101 (6), 555-9
DOI 10.1002/ijc.10641, PubMed 12237897
Oral contraceptives and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
J Natl Cancer Inst, 94 (23), 1773-9
DOI 10.1093/jnci/94.23.1773, PubMed 12464649
Publications 1996
Revmatisk sykdom og arvelighet: en pasientinformasjon
Haraldus Medical Communications, Trondheim, [6] bl.
BIBSYS 96111245x
Publications 1984
Genetic and clinical studies on Bechtherew's syndrome (hereditary multifocal relapsing inflammation)
P. Møller, Oslo, 1 b. (flere pag.)
BIBSYS 842055428, ISBN 82-90433-06-9