
Camilla Raiborg
- Assistant Group Leader, Senior Scientist (the Norwegian Cancer Society)
- +47 22 78 18 20
Camilla is in charge of the project Protein dynamics in tumor suppressor pathways
Camilla defended her PhD thesis in 2005 and continues as a postdoc in the Stenmark lab.
From the news:
Camilla Raiborg's work presented in popularised form on forskning.no:Filming live cancer cells
Nature article from Camilla Raiborg: Formation of cellular protrusions
Review in Nature about ESCRT proteins
Camilla's picture on the cover of the 2009 edition of Experimental Cell Research
Author network for Camilla Raiborg by COREMINE medical
Publications 2017
PtdIns3P controls mTORC1 signaling through lysosomal positioning
J Cell Biol, 216 (12), 4217-4233
PubMed 29030394
Suppressing mTORC1 on the lysosome
EMBO J, 36 (13), 1809-1810
PubMed 28623241
Publications 2016
Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
Trends Biochem Sci, 42 (1), 42-56
PubMed 27669649
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
J Cell Biol, 212 (5), 499-513
PubMed 26929449
Plasma membrane repairs by small GTPase Rab3a
J Cell Biol, 213 (6), 613-5
PubMed 27325788
Phosphoinositides in membrane contact sites
Biochem Soc Trans, 44 (2), 425-30
PubMed 27068950
ER-endosome contact sites in endosome positioning and protrusion outgrowth
Biochem Soc Trans, 44 (2), 441-6
PubMed 27068952
Interaction with epsin 1 regulates the constitutive clathrin-dependent internalization of ErbB3
Biochim Biophys Acta, 1863 (6 Pt A), 1179-88
PubMed 26975582
Publications 2015
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth
Nature, 520 (7546), 234-8
PubMed 25855459
ER-endosome contact sites: molecular compositions and functions
EMBO J, 34 (14), 1848-58
PubMed 26041457
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
Nature, 522 (7555), 231-5
PubMed 26040712
Publications 2014
An ER clamp for endosome fission
EMBO J, 34 (2), 136-7
PubMed 25502456
CK2 involvement in ESCRT-III complex phosphorylation
Arch Biochem Biophys, 545, 83-91
PubMed 24440309
ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4
Nat Cell Biol, 16 (6), 550-60
PubMed 24814515
Publications 2013
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
J Cell Biol, 202 (2), 331-49
PubMed 23878278
Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic
FEBS J, 280 (12), 2730-42
PubMed 23289851
Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling
Bioessays, 35 (10), 900-12
PubMed 23881848
Publications 2012
The PtdIns3P-binding protein Phafin 2 mediates epidermal growth factor receptor degradation by promoting endosome fusion
Traffic, 13 (11), 1547-63
PubMed 22816767
Publications 2011
SPG20, a novel biomarker for early detection of colorectal cancer, encodes a regulator of cytokinesis
Oncogene, 30 (37), 3967-78
PubMed 21499309
Cell biology. A helix for the final cut
Science, 331 (6024), 1533-4
PubMed 21436431
Publications 2010
PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody
Nat Cell Biol, 12 (4), 362-71
PubMed 20208530
Publications 2009
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
Nature, 458 (7237), 445-52
PubMed 19325624
Dual degradation mechanisms ensure disposal of NHE6 mutant protein associated with neurological disease
Exp Cell Res, 315 (17), 3014-27
PubMed 19619532
Publications 2008
An endosomally localized isoform of Eps15 interacts with Hrs to mediate degradation of epidermal growth factor receptor
J Cell Biol, 180 (6), 1205-18
PubMed 18362181
Publications 2007
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
J Cell Biol, 179 (3), 485-500
PubMed 17984323
Differential functions of Hrs and ESCRT proteins in endocytic membrane trafficking
Exp Cell Res, 314 (4), 801-13
PubMed 18031739
Publications 2006
The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor
Mol Biol Cell, 17 (6), 2513-23
PubMed 16554368
Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting
Nat Struct Mol Biol, 13 (3), 272-7
PubMed 16462748
Regulation of ubiquitin-binding proteins by monoubiquitination
Nat Cell Biol, 8 (2), 163-9
PubMed 16429130
Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor
Exp Cell Res, 312 (16), 3036-48
PubMed 16859684
Hrs makes receptors silent: a key to endosomal protein sorting
Crit Rev Oncog, 12 (3-4), 295, discussion 295-6
PubMed 17425508
A new side to ubiquitin
Trends Biochem Sci, 31 (10), 541-4
PubMed 16901703
Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains
J Cell Sci, 119 (Pt 12), 2414-24
PubMed 16720641
Publications 2005
Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain
J Biol Chem, 280 (20), 19600-6
PubMed 15755741
Publications 2004
The growth-regulatory protein HCRP1/hVps37A is a subunit of mammalian ESCRT-I and mediates receptor down-regulation
Mol Biol Cell, 15 (9), 4337-46
PubMed 15240819
Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits
Mol Biol Cell, 15 (8), 3591-604
PubMed 15194809
Publications 2003
STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes
J Biol Chem, 278 (14), 12513-21
PubMed 12551915
Phosphatidylinositol 3-phosphate is found in microdomains of early endosomes
Histochem Cell Biol, 120 (6), 445-53
PubMed 14618335
The E3 ubiquitin ligase AIP4 mediates ubiquitination and sorting of the G protein-coupled receptor CXCR4
Dev Cell, 5 (5), 709-22
PubMed 14602072
Protein sorting into multivesicular endosomes
Curr Opin Cell Biol, 15 (4), 446-55
PubMed 12892785
Publications 2002
Phosphorylation of Hrs downstream of the epidermal growth factor receptor
Eur J Biochem, 269 (16), 3881-7
PubMed 12180964
Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes
Nat Cell Biol, 4 (5), 394-8
PubMed 11988743
Hrs and endocytic sorting of ubiquitinated membrane proteins
Cell Struct Funct, 27 (6), 403-8
PubMed 12576633
Publications 2001
Hrs recruits clathrin to early endosomes
EMBO J, 20 (17), 5008-21
PubMed 11532964
Function of Hrs in endocytic trafficking and signalling
Biochem Soc Trans, 29 (Pt 4), 472-5
PubMed 11498011
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
J Cell Sci, 114 (Pt 12), 2255-63
PubMed 11493665
Publications 2000
Ultrastructural characterization of the delimiting membranes of isolated autophagosomes and amphisomes by freeze-fracture electron microscopy
Eur J Cell Biol, 79 (12), 871-82
PubMed 11152279
Autophagosome-associated variant isoforms of cytosolic enzymes
Biochem J, 352 Pt 3, 773-81
PubMed 11104685