
Kaisa Haglund
- Project Leader, Senior Scientist (the Norwegian Cancer Society)
- +47 22 78 19 24
Kaisa is in charge of the project Cytokinesis in development and carcinogenesis
From the news:
Ragnar Mørk legacy prize 2018 to Kaisa Haglund
Kaisa Haglund receives the Jahre prize for young medical researchers
Publications 2019
Centralspindlin Recruits ALIX to the Midbody during Cytokinetic Abscission in Drosophila via a Mechanism Analogous to Virus Budding
Curr Biol, 29 (20), 3538-3548.e7
DOI 10.1016/j.cub.2019.09.025, PubMed 31607533
Publications 2018
Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics
EMBO J, 37 (13)
DOI 10.15252/embj.201797741, PubMed 29858227
Publications 2017
Maternal prolactin during late pregnancy is important in generating nurturing behavior in the offspring
Proc Natl Acad Sci U S A, 114 (49), 13042-13047
DOI 10.1073/pnas.1621196114, PubMed 29158391
Publications 2016
Antibody Staining in Drosophila Germaria
Methods Mol Biol, 1457, 19-33
DOI 10.1007/978-1-4939-3795-0_3, PubMed 27557571
Arv1 promotes cell division by recruiting IQGAP1 and myosin to the cleavage furrow
Cell Cycle, 15 (5), 628-43
DOI 10.1080/15384101.2016.1146834, PubMed 27104745
Publications 2015
ALIX and ESCRT-III coordinately control cytokinetic abscission during germline stem cell division in vivo
PLoS Genet, 11 (1), e1004904
DOI 10.1371/journal.pgen.1004904, PubMed 25635693
Src64 controls a novel actin network required for proper ring canal formation in the Drosophila male germline
Development, 142 (23), 4107-18
DOI 10.1242/dev.124370, PubMed 26628094
Publications 2014
Investigating spermatogenesis in Drosophila melanogaster
Methods, 68 (1), 218-27
DOI 10.1016/j.ymeth.2014.04.020, PubMed 24798812
Publications 2013
Spatiotemporal control of Cindr at ring canals during incomplete cytokinesis in the Drosophila male germline
Dev Biol, 377 (1), 9-20
DOI 10.1016/j.ydbio.2013.02.021, PubMed 23499247
Publications 2012
The role of ubiquitylation in receptor endocytosis and endosomal sorting
J Cell Sci, 125 (Pt 2), 265-75
DOI 10.1242/jcs.091280, PubMed 22357968
Production of phosphatidylinositol 5-phosphate via PIKfyve and MTMR3 regulates cell migration
EMBO Rep, 14 (1), 57-64
DOI 10.1038/embor.2012.183, PubMed 23154468
Publications 2011
Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development
Commun Integr Biol, 4 (1), 1-9
DOI 10.4161/cib.4.1.13550, PubMed 21509167
A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis
PLoS One, 6 (3), e17086
DOI 10.1371/journal.pone.0017086, PubMed 21455500
Ligand-induced downregulation of TrkA is partly regulated through ubiquitination by Cbl
FEBS Lett, 585 (12), 1741-7
DOI 10.1016/j.febslet.2011.04.056, PubMed 21570973
Fibroblast growth factors and their receptors in cancer
Biochem J, 437 (2), 199-213
DOI 10.1042/BJ20101603, PubMed 21711248
Publications 2010
Cindr interacts with anillin to control cytokinesis in Drosophila melanogaster
Curr Biol, 20 (10), 944-50
DOI 10.1016/j.cub.2010.03.068, PubMed 20451383
CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice
EMBO J, 29 (14), 2421-32
DOI 10.1038/emboj.2010.120, PubMed 20551902
Publications 2009
Disruption of Vps4 and JNK function in Drosophila causes tumour growth
PLoS One, 4 (2), e4354
DOI 10.1371/journal.pone.0004354, PubMed 19194501
Publications 2007
Aberrant receptor signaling and trafficking as mechanisms in oncogenesis
Crit Rev Oncog, 13 (1), 39-74
DOI 10.1615/critrevoncog.v13.i1.20, PubMed 17956217
Publications 2006
Working out coupled monoubiquitination
Nat Cell Biol, 8 (11), 1218-9
DOI 10.1038/ncb1106-1218, PubMed 17077855
Specification of SUMO1- and SUMO2-interacting motifs
J Biol Chem, 281 (23), 16117-27
DOI 10.1074/jbc.M512757200, PubMed 16524884
Publications 2005
Ubiquitylation and cell signaling
EMBO J, 24 (19), 3353-9
DOI 10.1038/sj.emboj.7600808, PubMed 16148945
Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation
EMBO Rep, 6 (7), 635-41
DOI 10.1038/sj.embor.7400453, PubMed 15962011
Publications 2004
Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neurites
J Cell Sci, 117 (Pt 12), 2557-68
DOI 10.1242/jcs.01148, PubMed 15128873
Suppressors of T-cell receptor signaling Sts-1 and Sts-2 bind to Cbl and inhibit endocytosis of receptor tyrosine kinases
J Biol Chem, 279 (31), 32786-95
DOI 10.1074/jbc.M403759200, PubMed 15159412
Publications 2003
Distinct monoubiquitin signals in receptor endocytosis
Trends Biochem Sci, 28 (11), 598-603
DOI 10.1016/j.tibs.2003.09.005, PubMed 14607090
Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation
Nat Cell Biol, 5 (5), 461-6
DOI 10.1038/ncb983, PubMed 12717448
Identification of a novel proline-arginine motif involved in CIN85-dependent clustering of Cbl and down-regulation of epidermal growth factor receptors
J Biol Chem, 278 (41), 39735-46
DOI 10.1074/jbc.M304541200, PubMed 12874286
Publications 2002
Cbl-directed monoubiquitination of CIN85 is involved in regulation of ligand-induced degradation of EGF receptors
Proc Natl Acad Sci U S A, 99 (19), 12191-6
DOI 10.1073/pnas.192462299, PubMed 12218189
Past-A, a novel proton-associated sugar transporter, regulates glucose homeostasis in the brain
J Neurosci, 22 (21), 9160-5
DOI 10.1523/JNEUROSCI.22-21-09160.2002, PubMed 12417639