High throughput DNA sequencing of T-cell and B-cell receptors on single cell and bulk cell levels
Transcriptome analysis of disease relevant effector immune cells (B cells and T cells)
Development of novel diagnostic tools; detection of disease specific effector cells in peripheral blood and development of serological assays for immunoglobulin detection
Characterization of models for breakage of B-cell tolerance by use of immunoglobulin knock-in mouse model • Characterization of the autoimmune B-cell response and biology of the autoantigen transglutaminase 2
Vaz F, Lindeman I, Hoffmann HH, Skagen C, Steffensen AK, Bjørnholt JV, Tjønnfjord GE, Lundin KEA, Sollid LM, Iversen R(2026) Distinct systemic and gut IgA responses to bacteria of the human upper gastrointestinal tract Cell Rep, 45(8), 117721(in press) DOI 10.1016/j.celrep.2026.117721, PubMed 42497062
Bjornevik K, Mahler JV, Bilodeau PA, Rød BE, Romanow G, Mikami T, Anderson M, Bobrowski-Khoury N, Zhu H, Nguyen J, Sun Y, Matiello M, Housman D, Nourbakhsh B, Myhr KM, Torkildsen Ø, Sollid LM, Levy M, Drosu N(2026) CD4+ T cells reactive to Epstein-Barr virus late lytic antigens are enriched in individuals with multiple sclerosis Sci Transl Med, 18(858), eadz6566 DOI 10.1126/scitranslmed.adz6566, PubMed 42455903
Heggelund JE, Ali-Ahmad A, Johannesen MK, Sekulić N, Sollid LM(2026) Cryo-EM structure of the complex between transglutaminase 2 and the 45 kDa domain of fibronectin J Biol Chem, 113326(in press) DOI 10.1016/j.jbc.2026.113326, PubMed 42442505
