One of our main goals is to develop storage and transport technology for cultured stem cells of various origins. We anticipate this technology will be increasingly in demand as research in regenerative medicine becomes common practice. Improved treatment for patients with dry eye disease is another research focus, based on analyses of clinical data. Treatment of eye disease at the front and back of the eye is also an important part of our work, especially treatment of limbal stem cell deficiency using alternative cell types, such as cultured epidermal and oral mucosal cells. Isolation and culture of epidermal keratinocytes is thus a recent area of research interest. We specialize in stem cell research mainly in the areas of eye and skin.
Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations
Sci Rep, 9 (1), 7319
Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells
FASEB J, fj201802467R (in press)
Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients
Curr Eye Res, 1-7 (in press)