The Unit of Regenerative Medicine

The main goals of our research group are:

1)  to develop storage and transport technology for cultured stem cells of various origins (e.g., oral mucosal stem cells, Figure 1). We anticipate this technology will be increasingly in demand as research in regenerative medicine becomes common practice.

Figure 1. Possible steps in the treatment of limbal stem cell deficiency (Utheim et al., 2016).

 

2) Treatment of eye disease at the front and back of the eye is also an important part of our work, especially treatment of limbal stem cell deficiency using alternative cell types, such as cultured epidermal and oral mucosal stem cells (Figure 2). We specialize in stem cell research mainly in the areas of eye and skin.

Figure 2. Culture of human oral mucosal epithelial cells on hyaluronan hydrogel scaffold coated with collagen (right) compared to control (left) (Yazdani et al., 2019).

 

3) Improved diagnosis and treatment for patients with dry eye disease is another research focus, based on analyses of clinical data.

Figure 3. Stages of dry eye disease (Yazdani et al., 2019).

 

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