Publications published since 2000 from OUS - Regenerative Medicine Unit

301 publications found

Publications 2024

  1. Bjerager J, Magnø M, Chen X, Belmouhand M, Aass HCD, Reppe S, Heegaard S, Larsen M, Utheim TP (2024)
    Heritability of tear fluid cytokines in healthy twins
    Ocul Surf, 32, 145-153
    DOI 10.1016/j.jtos.2024.02.005, PubMed 38387783
  2. Chang K, Wu JG, Ma TL, Hsu SH, Cho KS, Yu Z, Lennikov A, Ashok A, Rajagopalan A, Chen MH, Su WF, Utheim TP, Chen DF (2024)
    Bioengineering strategy to promote CNS nerve growth and regeneration via chronic glutamate signaling
    Acta Biomater (in press)
    DOI 10.1016/j.actbio.2024.10.023, PubMed 39427766
  3. Enayati S, Chang K, Lennikov A, Yang M, Lee C, Ashok A, Elzaridi F, Yen C, Gunes K, Xie J, Cho KS, Utheim TP, Chen DF (2024)
    Optimal transcorneal electrical stimulation parameters for preserving photoreceptors in a mouse model of retinitis pigmentosa
    Neural Regen Res, 19 (11), 2543-2552
    DOI 10.4103/1673-5374.392888, PubMed 38526290
  4. Fineide F, Magnø M, Dahlø K, Kolko M, Heegaard S, Vehof J, Utheim TP (2024)
    Topical glaucoma medications - Possible implications on the meibomian glands
    Acta Ophthalmol, 102 (7), 735-748
    DOI 10.1111/aos.16728, PubMed 38822682
  5. Fjaervoll HK, Fjaervoll KA, Yang M, Reiten OK, Bair J, Lee C, Utheim TP, Dartt D (2024)
    Purinergic agonists increase [Ca2+]i in rat conjunctival goblet cells through ryanodine receptor type 3
    Am J Physiol Cell Physiol, 327 (3), C830-C843
    DOI 10.1152/ajpcell.00291.2024, PubMed 39099424
  6. Foessl I, Ackert-Bicknell CL, Kague E, Laskou F, Jakob F, Karasik D, Obermayer-Pietsch B, Co-authors, Alonso N, Bjørnerem Å, Brandi ML, Busse B, Calado Â, Cebi AH, Christou M, Curran KM, Hald JD, Semeraro MD, Douni E, Duncan EL, Duran I, Formosa MM, Gabet Y, Ghatan S, Gkitakou A et al. (2024)
    A perspective on muscle phenotyping in musculoskeletal research
    Trends Endocrinol Metab, 35 (6), 478-489
    DOI 10.1016/j.tem.2024.01.004, PubMed 38553405
  7. Ghannoum M, Waters PJ, Hovda KE, Choquette G, Elgstøen KBP, Nygaard I, Rootwelt H, Hickey D, Yazdani M, Bourque DK (2024)
    Can endogenous ethylene glycol production occur in humans? A detailed investigation of adult monozygotic twin sisters
    Clin Toxicol (Phila), 62 (11), 698-706
    DOI 10.1080/15563650.2024.2401076, PubMed 39327950
  8. Gundersen M, Jensen P, Nilsen C, Yazdani M, Utheim Ø, Sandås EM, Rootwelt H, Gundersen KG, Elgstøen KBP (2024)
    Method Development for Omics Analyses using Schirmer Strips
    Curr Eye Res, 49 (7), 708-716
    DOI 10.1080/02713683.2024.2335271, PubMed 38567868
  9. Gunes K, Chang K, Lennikov A, Tai WL, Chen J, ElZaridi F, Cho KS, Utheim TP, Dong Feng C (2024)
    Preservation of vision by transpalpebral electrical stimulation in mice with inherited retinal degeneration
    Front Cell Dev Biol, 12, 1412909
    DOI 10.3389/fcell.2024.1412909, PubMed 39206091
  10. Hadad R, Hedengran A, Barnils A, Petrovski G, Cvenkel B, Utheim TP, Dartt DA, Heegaard S, Kolko M (2024)
    Effect of chlorhexidine, povidone-iodine and betadine antiseptic eye drops on cultured human conjunctival goblet cell survival
    Acta Ophthalmol, 102 (7), 773-778
    DOI 10.1111/aos.16684, PubMed 38553957
  11. Jensen P, Nilsen C, Gundersen M, Gundersen KG, Potvin R, Gazerani P, Chen X, Utheim TP, Utheim ØA (2024)
    A Preservative-Free Approach - Effects on Dry Eye Signs and Symptoms After Cataract Surgery
    Clin Ophthalmol, 18, 591-604
    DOI 10.2147/OPTH.S446804, PubMed 38435373
  12. Khan AZ, Ueland HO, Bohman E, Tønseth KA, Utheim TP (2024)
    Ectropion
    Tidsskr Nor Laegeforen, 144 (1)
    DOI 10.4045/tidsskr.23.0309, PubMed 38258716
  13. Kärkkäinen V, Hannonen S, Rusanen M, Lehtola JM, Saari T, Uusitalo H, Leinonen V, Thiede B, Kaarniranta K, Koivisto AM, Utheim T (2024)
    Tear fluid reflects the altered protein expressions of Alzheimer's disease patients in proteins involved in protein repair and clearance system or the regulation of cytoskeleton
    J Alzheimers Dis, 13872877241295315 (in press)
    DOI 10.1177/13872877241295315, PubMed 39558606
  14. Malmin A, Thomseth VM, Førland PT, Aass HCD, Reppe S, Olsen MVT, Lindtjørn B, Chen X, Haugen IBK, Utheim TP, Forsaa VA (2024)
    Tear cytokine levels are reduced in patients treated with intravitreal injections
    Ocul Surf, 32, 222-226
    DOI 10.1016/j.jtos.2024.03.004, PubMed 38490478
  15. Mangiavacchi A, Morelli G, Reppe S, Saera-Vila A, Liu P, Eggerschwiler B, Zhang H, Bensaddek D, Casanova EA, Medina Gomez C, Prijatelj V, Della Valle F, Atinbayeva N, Izpisua Belmonte JC, Rivadeneira F, Cinelli P, Gautvik KM, Orlando V (2024)
    LINE-1 RNA triggers matrix formation in bone cells via a PKR-mediated inflammatory response
    EMBO J, 43 (17), 3587-3603
    DOI 10.1038/s44318-024-00143-z, PubMed 38951609
  16. Mangiavacchi A, Morelli G, Reppe S, Saera-Vila A, Liu P, Eggerschwiler B, Zhang H, Bensaddek D, Casanova EA, Medina Gomez C, Prijatelj V, Della Valle F, Atinbayeva N, Izpisua Belmonte JC, Rivadeneira F, Cinelli P, Gautvik KM, Orlando V (2024)
    Author Correction: LINE-1 RNA triggers matrix formation in bone cells via a PKR-mediated inflammatory response
    EMBO J, 43 (20), 4805-4806
    DOI 10.1038/s44318-024-00243-w, PubMed 39304794
  17. Mysen OMB, Hynnekleiv L, Magnø MS, Vehof J, Utheim TP (2024)
    Review of Hydroxypropyl Methylcellulose in Artificial Tears for the Treatment of Dry Eye Disease
    Acta Ophthalmol, 102 (8), 881-896
    DOI 10.1111/aos.16753, PubMed 39219040
  18. Nagarajan A, Laird J, Ugochukwu O, Reppe S, Gautvik K, Ross RD, Bennett DA, Rosen C, Kiel DP, Higginbotham LA, Seyfried NT, Lary CW (2024)
    Network Analysis of Brain and Bone Tissue Transcripts Reveals Shared Molecular Mechanisms Underlying Alzheimer's Disease and Related Dementias and Osteoporosis
    J Gerontol A Biol Sci Med Sci, 79 (11)
    DOI 10.1093/gerona/glae211, PubMed 39194133
  19. Naqvi M, Fineide F, Utheim TP, Charnock C (2024)
    Culture- and non-culture-based approaches reveal unique features of the ocular microbiome in dry eye patients
    Ocul Surf, 32, 123-129
    DOI 10.1016/j.jtos.2024.02.002, PubMed 38354907
  20. Naqvi M, Utheim TP, Charnock C (2024)
    Whole genome sequencing and characterization of Corynebacterium isolated from the healthy and dry eye ocular surface
    BMC Microbiol, 24 (1), 368
    DOI 10.1186/s12866-024-03517-9, PubMed 39342108
  21. Nøland ST, Magnø MS, Utheim TP, Chen X (2024)
    Sex Differences in the Prevalence of Meibomian Gland Dysfunction: A Mini Review
    Curr Eye Res, 49 (5), 447-457
    DOI 10.1080/02713683.2023.2301325, PubMed 38196124
  22. Reppe S, Gundersen S, Sandve GK, Wang Y, Andreassen OA, Medina-Gomez C, Rivadeneira F, Utheim TP, Hovig E, Gautvik KM (2024)
    Identification of Transcripts with Shared Roles in the Pathogenesis of Postmenopausal Osteoporosis and Cardiovascular Disease
    Int J Mol Sci, 25 (10)
    DOI 10.3390/ijms25105554, PubMed 38791593
  23. Rolić T, Yazdani M, Mandić S, Distante S (2024)
    Iron Metabolism, Calcium, Magnesium and Trace Elements: A Review
    Biol Trace Elem Res (in press)
    DOI 10.1007/s12011-024-04289-z, PubMed 38969940
  24. Tashbayev B, Chen X, Utheim TP (2024)
    Chalazion Treatment: A Concise Review of Clinical Trials
    Curr Eye Res, 49 (2), 109-118
    DOI 10.1080/02713683.2023.2279014, PubMed 37937798
  25. Torrissen M, Ytteborg E, Svensen H, Østbye TK, Berge G, Reppe S, Krasnov A, Ruyter B (2024)
    Effects of n-3 very-long-chain polyunsaturated fatty acids on bone mineralization
    Br J Nutr, 1-48 (in press)
    DOI 10.1017/S0007114524003052, PubMed 39610358
  26. Utheim TP, Chen X, Fineide F, Steinkjer T, Heegaard S, Kolko M, Dartt DA, Khan AZ (2024)
    Response predictors of a topical corticosteroid-based regimen for dry eyes: A real-life study
    Acta Ophthalmol (in press)
    DOI 10.1111/aos.16758, PubMed 39344883
  27. van Velthoven AJH, Utheim TP, Notara M, Bremond-Gignac D, Figueiredo FC, Skottman H, Aberdam D, Daniels JT, Ferrari G, Grupcheva C, Koppen C, Parekh M, Ritter T, Romano V, Ferrari S, Cursiefen C, Lagali N, LaPointe VLS, Dickman MM (2024)
    Corrigendum to "Future directions in managing aniridia-associated keratopathy" [Surv Ophthalmol 68 (2023) 940-956]
    Surv Ophthalmol, 69 (2), 300-301
    DOI 10.1016/j.survophthal.2024.01.001, PubMed 38326136
  28. Winiarczyk M, Thiede B, Utheim TP, Kaarniranta K, Winiarczyk D, Michalak K, Mackiewicz J (2024)
    Oxidative Stress, Persistent Inflammation and Blood Coagulation Alterations in Serum Proteome of Patients with Neovascular Age-Related Macular Degeneration
    Life (Basel), 14 (5)
    DOI 10.3390/life14050624, PubMed 38792644
  29. Yazdani M (2024)
    Cellular and Molecular Responses to Mitochondrial DNA Deletions in Kearns-Sayre Syndrome: Some Underlying Mechanisms
    Mol Neurobiol, 61 (8), 5665-5679
    DOI 10.1007/s12035-024-03938-7, PubMed 38224444

Publications 2023

  1. Ashok A, Tai WL, Lennikov A, Chang K, Chen J, Li B, Cho KS, Utheim TP, Chen DF (2023)
    Electrical stimulation alters DNA methylation and promotes neurite outgrowth
    J Cell Biochem, 124 (10), 1530-1545
    DOI 10.1002/jcb.30462, PubMed 37642194
  2. Ballet B, Behaegel J, Reppe S, Consejo A, Aass HC, Utheim TP, Koppen C, Ní Dhubhghaill S (2023)
    Ocular Surface Homeostasis After Scleral Lens Usage
    Eye Contact Lens, 49 (11), 459-463
    DOI 10.1097/ICL.0000000000001027, PubMed 37651199
  3. Cross T, Haug KBF, Brusletto BS, Ommundsen SK, Trøseid AS, Aspelin T, Olstad OK, Aass HCD, Galtung HK, Utheim TP, Jensen JL, Øvstebø R (2023)
    Non-Coding RNA in Salivary Extracellular Vesicles: A New Frontier in Sjögren's Syndrome Diagnostics?
    Int J Mol Sci, 24 (17)
    DOI 10.3390/ijms241713409, PubMed 37686214
  4. Cross T, Øvstebø R, Brusletto BS, Trøseid AS, Olstad OK, Aspelin T, Jackson CJ, Chen X, Utheim TP, Haug KBF (2023)
    RNA Profiles of Tear Fluid Extracellular Vesicles in Patients with Dry Eye-Related Symptoms
    Int J Mol Sci, 24 (20)
    DOI 10.3390/ijms242015390, PubMed 37895069
  5. Erøy ÅA, Utheim TP, Sundling V (2023)
    Cross-sectional Study Exploring Vision-related Quality of Life in Dry Eye Disease in a Norwegian Optometric Practice
    Optom Vis Sci, 100 (10), 679-687
    DOI 10.1097/OPX.0000000000002058, PubMed 37751404
  6. Fineide F, Magnø MS, Khan AZ, Chen X, Vehof J, Utheim TP (2023)
    Intense pulsed light treatment in meibomian gland dysfunction: Past, present, and future
    Acta Ophthalmol, 102 (4), e414-e442
    DOI 10.1111/aos.15759, PubMed 37702308
  7. Fineide FA, Tashbayev B, Elgstøen KBP, Sandås EM, Rootwelt H, Hynne H, Chen X, Ræder S, Vehof J, Dartt D, Jensen JL, Utheim TP (2023)
    Tear and Saliva Metabolomics in Evaporative Dry Eye Disease in Females
    Metabolites, 13 (11)
    DOI 10.3390/metabo13111125, PubMed 37999221
  8. Fjærvoll HK, Fjærvoll KA, Yang M, Bair J, Utheim TP, Dartt DA (2023)
    Purinergic 2X 4 (P2X4), but not P2X7, receptors increase cytosolic [Ca2+] and stimulate mucin secretion in rat conjunctival goblet cells to maintain ocular surface health
    Exp Eye Res, 235, 109614
    DOI 10.1016/j.exer.2023.109614, PubMed 37580003
  9. Fries FN, Moslemani K, Utheim TP, Seitz B, Käsmann-Kellner B, Lagali NS (2023)
    Early ocular surface and tear film status in congenital aniridia indicates a supportive treatment window
    Br J Ophthalmol, 108 (1), 30-36
    DOI 10.1136/bjo-2021-320774, PubMed 36517210
  10. Graae Jensen P, Gundersen M, Nilsen C, Gundersen KG, Potvin R, Gazerani P, Chen X, Utheim TP, Utheim ØA (2023)
    Prevalence of Dry Eye Disease Among Individuals Scheduled for Cataract Surgery in a Norwegian Cataract Clinic
    Clin Ophthalmol, 17, 1233-1243
    DOI 10.2147/OPTH.S407805, PubMed 37138823
  11. Hedengran A, Freiberg J, May Hansen P, Boix-Lemonche G, Utheim TP, Dartt DA, Petrovski G, Heegaard S, Kolko M (2023)
    Comparing the effect of benzalkonium chloride-preserved, polyquad-preserved, and preservative-free prostaglandin analogue eye drops on cultured human conjunctival goblet cells
    J Optom, 17 (1), 100481
    DOI 10.1016/j.optom.2023.100481, PubMed 37788596
  12. Hiller JK, Sandås EM, Rootwelt H, Østeby Vassli A, Utheim TP, Moe MC, Elgstøen KBP, Petrovski G (2023)
    Ex Vivo Pig Eye Model for Studying Diffusion of Acylcarnitines with Different Physicochemical Properties
    J Ocul Pharmacol Ther, 39 (5), 324-331
    DOI 10.1089/jop.2022.0159, PubMed 37219540
  13. Hynnekleiv L, Magno M, Moschowits E, Tønseth KA, Vehof J, Utheim TP (2023)
    A comparison between hyaluronic acid and other single ingredient eye drops for dry eye, a review
    Acta Ophthalmol, 102 (1), 25-37
    DOI 10.1111/aos.15675, PubMed 37042308
  14. Khan AZ, Tønseth KA, Koidl A, Utheim TP (2023)
    Suture materials
    Tidsskr Nor Laegeforen, 143 (10)
    DOI 10.4045/tidsskr.22.0708, PubMed 37376937
  15. Khan AZ, Tønseth KA, Koidl A, Utheim TP (2023)
    [Not Available]
    Tidsskr Nor Laegeforen, 143
    DOI 10.4045/tidsskr.23.0446, PubMed 37376981
  16. Kolko M, Gazzard G, Baudouin C, Beier S, Brignole-Baudouin F, Cvenkel B, Fineide F, Hedengran A, Hommer A, Jespersen E, Messmer EM, Murthy R, Sullivan AG, Tatham AJ, Utheim TP, Vittrup M, Sullivan DA (2023)
    Impact of glaucoma medications on the ocular surface and how ocular surface disease can influence glaucoma treatment
    Ocul Surf, 29, 456-468
    DOI 10.1016/j.jtos.2023.05.012, PubMed 37302545
  17. Lyngstadaas AV, Olsen MV, Bair J, Yang M, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2023)
    Anti-Inflammatory and Pro-Resolving Actions of the N-Terminal Peptides Ac2-26, Ac2-12, and Ac9-25 of Annexin A1 on Conjunctival Goblet Cell Function
    Am J Pathol, 193 (11), 1817-1832
    DOI 10.1016/j.ajpath.2023.05.020, PubMed 37423551
  18. Magno MS, Moschowits E, Morthen MK, Beining MW, Jansonius NM, Hammond CJ, Utheim TP, Vehof J (2023)
    Greater adherence to a mediterranean diet is associated with lower C-reactive protein (CRP) levels, but not to lower odds of having dry eye disease
    Ocul Surf, 30, 196-203
    DOI 10.1016/j.jtos.2023.09.013, PubMed 37783428
  19. Magno MS, Olafsson J, Beining M, Moschowits E, Lagali N, Wolffsohn JS, Craig JP, Vehof J, Dartt DA, Utheim TP (2023)
    Risk associated with treatments for meibomian gland dysfunction
    Cont Lens Anterior Eye, 46 (2), 101818
    DOI 10.1016/j.clae.2023.101818, PubMed 36754735
  20. Malmin A, Thomseth VM, Førland PT, Khan AZ, Hetland HB, Chen X, Haugen IK, Utheim TP, Forsaa VA (2023)
    Associations between Serial Intravitreal Injections and Dry Eye
    Ophthalmology, 130 (5), 509-515
    DOI 10.1016/j.ophtha.2023.01.009, PubMed 36693594
  21. Medina-Gomez C, Mullin BH, Chesi A, Prijatelj V, Kemp JP, Shochat-Carvalho C, Trajanoska K, Wang C, Joro R, Evans TE, Schraut KE, Li-Gao R, Ahluwalia TS, Zillikens MC, Zhu K, Mook-Kanamori DO, Evans DS, Nethander M, Knol MJ, Thorleifsson G, Prokic I, Zemel B, Broer L, McGuigan FE, van Schoor NM et al. (2023)
    Bone mineral density loci specific to the skull portray potential pleiotropic effects on craniosynostosis
    Commun Biol, 6 (1), 691
    DOI 10.1038/s42003-023-04869-0, PubMed 37402774
  22. Morthen MK, Magno MS, Utheim TP, Hammond CJ, Vehof J (2023)
    The work-related burden of dry eye
    Ocul Surf, 28, 30-36
    DOI 10.1016/j.jtos.2023.01.006, PubMed 36690155
  23. Muttuvelu DV, Cehofski LJ, Holtz J, Utheim TP, Chen X, Vorum H, Heegaard S, Rasmussen MLR, Khan AM, Abduljabar AB, Honoré B (2023)
    Meibomian Gland Dysfunction Is Associated with Low Levels of Immunoglobulin Chains and Cystatin-SN
    Int J Mol Sci, 24 (20)
    DOI 10.3390/ijms242015115, PubMed 37894795
  24. Muttuvelu DV, Cehofski LJ, Muhammad MGF, Chen X, Utheim TP, Khan AM, Abduljabar AB, Kristensen K, Rasmussen MLR, Vorum H, Heegaard S, Honoré B (2023)
    Anterior blepharitis is associated with elevated plectin levels consistent with a pronounced intracellular response
    Ocul Surf, 29, 444-455
    DOI 10.1016/j.jtos.2023.06.010, PubMed 37348651
  25. Muttuvelu DV, Cehofski LJ, Utheim TP, Chen X, Vorum H, Rasmussen MLR, Heegaard S, Khan AM, Abduljabar AB, Honoré B (2023)
    Tear film proteome changes following Tobradex® therapy in anterior blepharitis
    Acta Ophthalmol, 102 (4), e565-e576
    DOI 10.1111/aos.15792, PubMed 37837306
  26. Nguyen L, Magno MS, Utheim TP, Hammond CJ, Vehof J (2023)
    The relationship between sedentary behavior and dry eye disease
    Ocul Surf, 28, 11-17
    DOI 10.1016/j.jtos.2023.01.002, PubMed 36621639
  27. Salvador CL, Oppebøen M, Vassli AØ, Pfeiffer HCV, Varhaug KN, Elgstøen KBP, Yazdani M (2023)
    Increased Sphingomyelin and Free Sialic Acid in Cerebrospinal Fluid of Kearns-Sayre Syndrome: New Findings Using Untargeted Metabolomics
    Pediatr Neurol, 143, 68-76
    DOI 10.1016/j.pediatrneurol.2023.02.016, PubMed 37018879
  28. Storås AM, Fineide F, Magnø M, Thiede B, Chen X, Strümke I, Halvorsen P, Galtung H, Jensen JL, Utheim TP, Riegler MA (2023)
    Using machine learning model explanations to identify proteins related to severity of meibomian gland dysfunction
    Sci Rep, 13 (1), 22946
    DOI 10.1038/s41598-023-50342-7, PubMed 38135766
  29. van Velthoven AJH, Utheim TP, Notara M, Bremond-Gignac D, Figueiredo FC, Skottman H, Aberdam D, Daniels JT, Ferrari G, Grupcheva C, Koppen C, Parekh M, Ritter T, Romano V, Ferrari S, Cursiefen C, Lagali N, LaPointe VLS, Dickman MM (2023)
    Future directions in managing aniridia-associated keratopathy
    Surv Ophthalmol, 68 (5), 940-956
    DOI 10.1016/j.survophthal.2023.04.003, PubMed 37146692
  30. Yazdani M (2023)
    Tear film lipid layer and corneal oxygenation: a new function?
    Eye (Lond), 37 (17), 3534-3541
    DOI 10.1038/s41433-023-02557-1, PubMed 37138094
  31. Zheng J, Wheeler E, Pietzner M, Andlauer TFM, Yau MS, Hartley AE, Brumpton BM, Rasheed H, Kemp JP, Frysz M, Robinson J, Reppe S, Prijatelj V, Gautvik KM, Falk L, Maerz W, Gergei I, Peyser PA, Kavousi M, de Vries PS, Miller CL, Bos M, van der Laan SW, Malhotra R, Herrmann M et al. (2023)
    Lowering of Circulating Sclerostin May Increase Risk of Atherosclerosis and Its Risk Factors: Evidence From a Genome-Wide Association Meta-Analysis Followed by Mendelian Randomization
    Arthritis Rheumatol, 75 (10), 1781-1792
    DOI 10.1002/art.42538, PubMed 37096546

Publications 2022

  1. Ashok A, Pooranawattanakul S, Tai WL, Cho KS, Utheim TP, Cestari DM, Chen DF (2022)
    Epigenetic Regulation of Optic Nerve Development, Protection, and Repair
    Int J Mol Sci, 23 (16)
    DOI 10.3390/ijms23168927, PubMed 36012190
  2. Beining MW, Magnø MS, Moschowits E, Olafsson J, Vehof J, Dartt DA, Utheim TP (2022)
    In-office thermal systems for the treatment of dry eye disease
    Surv Ophthalmol, 67 (5), 1405-1418
    DOI 10.1016/j.survophthal.2022.02.007, PubMed 35192836
  3. Bhandari M, Nguyen S, Yazdani M, Utheim TP, Hagesaether E (2022)
    The Therapeutic Benefits of Nanoencapsulation in Drug Delivery to the Anterior Segment of the Eye: A Systematic Review
    Front Pharmacol, 13, 903519
    DOI 10.3389/fphar.2022.903519, PubMed 35645827
  4. Botten N, Hodges RR, Bair J, Utheim TP, Serhan CN, Yang M, Dartt DA (2022)
    Resolvin D2 uses multiple Ca2+ -dependent signaling pathways to stimulate mucin secretion in rat and human conjunctival goblet cells
    J Cell Physiol, 237 (10), 3816-3833
    DOI 10.1002/jcp.30854, PubMed 36066128
  5. Böhm HO, Yazdani M, Sandås EM, Østeby Vassli A, Kristensen E, Rootwelt H, Skogvold HB, Brodtkorb E, Elgstøen KBP (2022)
    Global Metabolomics Discovers Two Novel Biomarkers in Pyridoxine-Dependent Epilepsy Caused by ALDH7A1 Deficiency
    Int J Mol Sci, 23 (24)
    DOI 10.3390/ijms232416061, PubMed 36555701
  6. Chen X, Badian RA, Hynne H, Tashbayev B, Hove LH, Jensen JL, Utheim TP (2022)
    Morphology of Meibomian Glands in a 65-Year-Old Norwegian Population without Dry Eye Disease
    J Clin Med, 11 (3)
    DOI 10.3390/jcm11030527, PubMed 35159978
  7. Datta HK, Kringen MK, Tuck SP, Salpingidou G, Olstad OK, Gautvik KM, Cockell SJ, Gautvik VT, Prediger M, Wu JJ, Birch MA, Reppe S (2022)
    Mechanical-Stress-Related Epigenetic Regulation of ZIC1 Transcription Factor in the Etiology of Postmenopausal Osteoporosis
    Int J Mol Sci, 23 (6)
    DOI 10.3390/ijms23062957, PubMed 35328378
  8. Eidet JR, Chen X, Ræder S, Badian RA, Utheim TP (2022)
    Seasonal variations in presenting symptoms and signs of dry eye disease in Norway
    Sci Rep, 12 (1), 21046
    DOI 10.1038/s41598-022-25557-9, PubMed 36473933
  9. Enayati S, Zhou W, Stojanovic A, Utheim TP, Bian Z, Feng Y, Chen X (2022)
    Effect of femtosecond laser cutting parameters on the results of small-incision lenticule extraction
    J Cataract Refract Surg, 48 (11), 1253-1259
    DOI 10.1097/j.jcrs.0000000000000965, PubMed 35537865
  10. Feng Y, Reinstein DZ, Nitter T, Archer TJ, McAlinden C, Chen X, Bertelsen G, Utheim TP, Stojanovic A (2022)
    Heidelberg Anterion Swept-Source OCT Corneal Epithelial Thickness Mapping: Repeatability and Agreement With Optovue Avanti
    J Refract Surg, 38 (6), 356-363
    DOI 10.3928/1081597X-20220414-01, PubMed 35686707
  11. Fineide F, Lagali N, Adil MY, Arita R, Kolko M, Vehof J, Utheim TP (2022)
    Topical glaucoma medications - Clinical implications for the ocular surface
    Ocul Surf, 26, 19-49
    DOI 10.1016/j.jtos.2022.07.007, PubMed 35921942
  12. Fineide F, Storås AM, Chen X, Magnø MS, Yazidi A, Riegler MA, Utheim TP (2022)
    Predicting an unstable tear film through artificial intelligence
    Sci Rep, 12 (1), 21416
    DOI 10.1038/s41598-022-25821-y, PubMed 36496510
  13. Fjaervoll K, Fjaervoll H, Magno M, Nøland ST, Dartt DA, Vehof J, Utheim TP (2022)
    Review on the possible pathophysiological mechanisms underlying visual display terminal-associated dry eye disease
    Acta Ophthalmol, 100 (8), 861-877
    DOI 10.1111/aos.15150, PubMed 35441459
  14. Gautvik KM, Olstad OK, Raue U, Gautvik VT, Kvernevik KJ, Utheim TP, Ravnum S, Kirkegaard C, Wiig H, Jones G, Pilling LC, Trappe S, Raastad T, Reppe S (2022)
    Heavy-load exercise in older adults activates vasculogenesis and has a stronger impact on muscle gene expression than in young adults
    Eur Rev Aging Phys Act, 19 (1), 23
    DOI 10.1186/s11556-022-00304-1, PubMed 36182918
  15. Gautvik KM, Sachse D, Hinton AC, Olstad OK, Kiel DP, Hsu YH, Utheim TP, Lary CW, Reppe S (2022)
    In silico discovery of blood cell macromolecular associations
    BMC Genom Data, 23 (1), 57
    DOI 10.1186/s12863-022-01077-3, PubMed 35879676
  16. Grgic O, Prijatelj V, Dudakovic A, Vucic S, Dhamo B, Trajanoska K, Monnereau C, Zrimsek M, Gautvik KM, Reppe S, Shimizu E, Haworth S, Timpson NJ, Jaddoe VWV, Jarvelin MR, Evans D, Uitterlinden AG, Ongkosuwito EM, van Wijnen AJ, Medina-Gomez C, Rivadeneira F, Wolvius EB (2022)
    Novel Genetic Determinants of Dental Maturation in Children
    J Dent Res, 102 (3), 349-356
    DOI 10.1177/00220345221132268, PubMed 36437532
  17. Haugen ØP, Khuu C, Weidemann HM, Utheim TP, Bergersen LH (2022)
    Transcriptomic and functional studies reveal miR-431-5p as a tumour suppressor in pancreatic ductal adenocarcinoma cells
    Gene, 822, 146346
    DOI 10.1016/j.gene.2022.146346, PubMed 35182679
  18. Hynne H, Aqrawi LA, Jensen JL, Thiede B, Palm Ø, Amdal CD, Westgaard KL, Herlofson BB, Utheim TP, Galtung HK (2022)
    Proteomic Profiling of Saliva and Tears in Radiated Head and Neck Cancer Patients as Compared to Primary Sjögren's Syndrome Patients
    Int J Mol Sci, 23 (7)
    DOI 10.3390/ijms23073714, PubMed 35409074
  19. Hynne H, Sandås EM, Elgstøen KBP, Rootwelt H, Utheim TP, Galtung HK, Jensen JL (2022)
    Saliva Metabolomics in Dry Mouth Patients with Head and Neck Cancer or Sjögren's Syndrome
    Cells, 11 (3)
    DOI 10.3390/cells11030323, PubMed 35159133
  20. Hynnekleiv L, Magno M, Vernhardsdottir RR, Moschowits E, Tønseth KA, Dartt DA, Vehof J, Utheim TP (2022)
    Hyaluronic acid in the treatment of dry eye disease
    Acta Ophthalmol, 100 (8), 844-860
    DOI 10.1111/aos.15159, PubMed 35514082
  21. Jackson CJ, Gundersen KG, Tong L, Utheim TP (2022)
    Dry eye disease and proteomics
    Ocul Surf, 24, 119-128
    DOI 10.1016/j.jtos.2022.03.001, PubMed 35278720
  22. Jackson CJ, Naqvi M, Gundersen KG, Utheim TP (2022)
    Role of stem cells in regenerative treatment of dry eye disease caused by lacrimal gland dysfunction
    Acta Ophthalmol, 101 (4), 360-375
    DOI 10.1111/aos.15629, PubMed 36564971
  23. Jirsova K, Levova K, Kalousova M, Fales I, Frankova V, Vesela V, Zima T, Utheim TP, Bednar J (2022)
    Time and Temperature Stability of TGF-β1, EGF and IGF-1 in 20% and 100% Human Serum
    Folia Biol (Praha), 68 (2), 45-49
    PubMed 36384261
  24. Kamøy B, Magno M, Nøland ST, Moe MC, Petrovski G, Vehof J, Utheim TP (2022)
    Video display terminal use and dry eye: preventive measures and future perspectives
    Acta Ophthalmol, 100 (7), 723-739
    DOI 10.1111/aos.15105, PubMed 35122403
  25. Khan AZ, Utheim TP, Byholt M, Fiabema T, Sylvester-Jensen HC, Tønseth KA (2022)
    Skin grafting
    Tidsskr Nor Laegeforen, 142 (8)
    DOI 10.4045/tidsskr.21.0671, PubMed 35635412
  26. Landsend ECS, Olafsson J, Lai X, Aass HCD, Utheim TP (2022)
    Change in Ocular Surface Staining during Eyelid Warming Is Related to Tear Cytokine Levels
    J Ophthalmol, 2022, 5103231
    DOI 10.1155/2022/5103231, PubMed 35967518
  27. Lennikov A, Yang M, Chang K, Pan L, Saddala MS, Lee C, Ashok A, Cho KS, Utheim TP, Chen DF (2022)
    Direct modulation of microglial function by electrical field
    Front Cell Dev Biol, 10, 980775
    DOI 10.3389/fcell.2022.980775, PubMed 36158207
  28. Liu P, Lin X, Chen X, Utheim TP, Gao W, Yan Y, Wu S (2022)
    Neuronal Intranuclear Inclusion Disease-Related Neurotrophic Keratitis: A Case Report
    Brain Sci, 12 (6)
    DOI 10.3390/brainsci12060782, PubMed 35741666
  29. Nguyen L, Magno MS, Utheim TP, Jansonius NM, Hammond CJ, Vehof J (2022)
    The relationship between habitual water intake and dry eye disease
    Acta Ophthalmol, 101 (1), 65-73
    DOI 10.1111/aos.15227, PubMed 35941821
  30. Salvanos P, Björnsson HD, Vitelli V, Bragadόttir R, Moe MC, Utheim TP (2022)
    Autofluorescence Imaging in the Long-Term Follow-Up of Scleral Buckling Surgery for Retinal Detachment
    J Ophthalmol, 2022, 2119439
    DOI 10.1155/2022/2119439, PubMed 35265365
  31. Schjerven Magno M, Olafsson J, Beining M, Moschowits E, Lagali N, Wolffsohn JS, Craig JP, Vehof J, Dartt DA, Utheim TP (2022)
    Hot towels: The bedrock of Meibomian gland dysfunction treatment - A review
    Cont Lens Anterior Eye, 46 (2), 101775
    DOI 10.1016/j.clae.2022.101775, PubMed 36715292
  32. Thein AS, Hedengran A, Azuara-Blanco A, Arita R, Cvenkel B, Gazzard G, Heegaard S, de Paiva CS, Petrovski G, Prokosch-Willing V, Utheim TP, Virgili G, Kolko M (2022)
    Adverse Effects and Safety in Glaucoma Patients: Agreement on Clinical Trial Outcomes for Reports on Eye Drops (ASGARD)-A Delphi Consensus Statement
    Am J Ophthalmol, 241, 190-197
    DOI 10.1016/j.ajo.2022.05.007, PubMed 35594917
  33. Vernhardsdottir RR, Magno MS, Hynnekleiv L, Lagali N, Dartt DA, Vehof J, Jackson CJ, Utheim TP (2022)
    Antibiotic treatment for dry eye disease related to meibomian gland dysfunction and blepharitis - A review
    Ocul Surf, 26, 211-221
    DOI 10.1016/j.jtos.2022.08.010, PubMed 36210626
  34. Yang M, Fjærvoll HK, Fjærvoll KA, Wang NH, Utheim TP, Serhan CN, Dartt DA (2022)
    Sex-based differences in conjunctival goblet cell responses to pro-inflammatory and pro-resolving mediators
    Sci Rep, 12 (1), 16305
    DOI 10.1038/s41598-022-20177-9, PubMed 36175572
  35. Yang M, Lennikov A, Chang K, Ashok A, Lee C, Cho KS, Utheim TP, Dartt DA, Chen DF (2022)
    Transcorneal but not transpalpebral electrical stimulation disrupts mucin homeostasis of the ocular surface
    BMC Ophthalmol, 22 (1), 490
    DOI 10.1186/s12886-022-02717-z, PubMed 36522696
  36. Yazdani M (2022)
    Uncontrolled Oxygen Levels in Cultures of Retinal Pigment Epithelium: Have We Missed the Obvious?
    Curr Eye Res, 47 (5), 651-660
    DOI 10.1080/02713683.2022.2050264, PubMed 35243933
  37. Yazdani M, Distante S, Mørkrid L, Ulvik RJ, Bolann BJ (2022)
    Bloodlettings in Hemochromatosis Result in Increased Blood Lead (Pb) Concentrations
    Biol Trace Elem Res, 201 (7), 3193-3201
    DOI 10.1007/s12011-022-03424-y, PubMed 36168081

Publications 2021

  1. Badian RA, Utheim TP, Chen X, Utheim ØA, Ræder S, Ystenæs AE, Aakre BM, Sundling V (2021)
    Meibomian gland dysfunction is highly prevalent among first-time visitors at a Norwegian dry eye specialist clinic
    Sci Rep, 11 (1), 23412
    DOI 10.1038/s41598-021-02738-6, PubMed 34862425
  2. Bendiksen Skogvold H, Yazdani M, Sandås EM, Østeby Vassli A, Kristensen E, Haarr D, Rootwelt H, Elgstøen KBP (2021)
    A pioneer study on human 3-nitropropionic acid intoxication: Contributions from metabolomics
    J Appl Toxicol, 42 (5), 818-829
    DOI 10.1002/jat.4259, PubMed 34725838
  3. Chang K, Enayati S, Cho KS, Utheim TP, Chen DF (2021)
    Non-invasive electrical stimulation as a potential treatment for retinal degenerative diseases
    Neural Regen Res, 16 (8), 1558-1559
    DOI 10.4103/1673-5374.303015, PubMed 33433481
  4. Chen X, Badian RA, Hynne H, Amdal CD, Herlofson BB, Utheim ØA, Westgaard KL, Fineide F, Jensen JL, Utheim TP (2021)
    Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer
    Sci Rep, 11 (1), 22419
    DOI 10.1038/s41598-021-01844-9, PubMed 34789830
  5. Fineide F, Chen X, Bjellaas T, Vitelli V, Utheim TP, Jensen JL, Galtung HK (2021)
    Characterization of Lipids in Saliva, Tears and Minor Salivary Glands of Sjögren's Syndrome Patients Using an HPLC/MS-Based Approach
    Int J Mol Sci, 22 (16)
    DOI 10.3390/ijms22168997, PubMed 34445702
  6. Fjaervoll H, Fjaervoll K, Magno M, Moschowits E, Vehof J, Dartt DA, Utheim TP (2021)
    The association between visual display terminal use and dry eye: a review
    Acta Ophthalmol, 100 (4), 357-375
    DOI 10.1111/aos.15049, PubMed 34697901
  7. Hamdani EH, Popek M, Frontczak-Baniewicz M, Utheim TP, Albrecht J, Zielińska M, Chaudhry FA (2021)
    Perturbation of astroglial Slc38 glutamine transporters by NH4+ contributes to neurophysiologic manifestations in acute liver failure
    FASEB J, 35 (7), e21588
    DOI 10.1096/fj.202001712RR, PubMed 34169573
  8. Hikage F, Lennikov A, Mukwaya A, Lachota M, Ida Y, Utheim TP, Chen DF, Huang H, Ohguro H (2021)
    NF-κB activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization in mice
    Exp Cell Res, 403 (1), 112581
    DOI 10.1016/j.yexcr.2021.112581, PubMed 33811906
  9. Khan AZ, Utheim TP, Jackson CJ, Tønseth KA, Eidet JR (2021)
    Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells
    Front Med (Lausanne), 8, 686774
    DOI 10.3389/fmed.2021.686774, PubMed 34485330
  10. Khan AZ, Utheim TP, Jackson CJ, Tønseth KA, Eidet JR (2021)
    Corrigendum: Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells
    Front Med (Lausanne), 8, 775351
    DOI 10.3389/fmed.2021.775351, PubMed 34676230
  11. Khan AZ, Utheim TP, Moe MC, Aass HCD, Sapkota D, Vallenari EM, Eidet JR (2021)
    The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
    Curr. Eye Res., 46 (4), 504-514
    DOI 10.1080/02713683.2020.1809001
  12. Landsend ECS, Lagali N, Utheim TP (2021)
    Congenital aniridia - A comprehensive review of clinical features and therapeutic approaches
    Surv Ophthalmol, 66 (6), 1031-1050
    DOI 10.1016/j.survophthal.2021.02.011, PubMed 33675823
  13. Landsend ECS, Lagali N, Utheim TP (2021)
    Authors' response to letter to the editor: Congenital aniridia - a comprehensive review of clinical features and therapeutic approach
    Surv Ophthalmol, 67 (2), 629-630
    DOI 10.1016/j.survophthal.2021.11.001, PubMed 34748793
  14. Lyngstadaas AV, Olsen MV, Bair JA, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2021)
    Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca2+ and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases
    Front Immunol, 12, 618653
    DOI 10.3389/fimmu.2021.618653, PubMed 33968020
  15. Magno M, Moschowits E, Arita R, Vehof J, Utheim TP (2021)
    Intraductal meibomian gland probing and its efficacy in the treatment of meibomian gland dysfunction
    Surv Ophthalmol, 66 (4), 612-622
    DOI 10.1016/j.survophthal.2020.11.005, PubMed 33352147
  16. Magno MS, Olafsson J, Beining M, Moschowits E, Lagali N, Wolffsohn JS, Craig JP, Dartt DA, Vehof J, Utheim TP (2021)
    Chambered warm moist air eyelid warming devices - a review
    Acta Ophthalmol, 100 (5), 499-510
    DOI 10.1111/aos.15052, PubMed 34750979
  17. Maurizi A, Ponzetti M, Gautvik KM, Reppe S, Teti A, Rucci N (2021)
    Lipocalin 2 serum levels correlate with age and bone turnover biomarkers in healthy subjects but not in postmenopausal osteoporotic women
    Bone Rep, 14, 101059
    DOI 10.1016/j.bonr.2021.101059, PubMed 34026950
  18. Morthen MK, Magno MS, Utheim TP, Snieder H, Jansonius N, Hammond CJ, Vehof J (2021)
    The vision-related burden of dry eye
    Ocul Surf, 23, 207-215
    DOI 10.1016/j.jtos.2021.10.007, PubMed 34743866
  19. Müllertz O, Hedengran A, Mouhammad ZA, Freiberg J, Nagymihály R, Jacobsen J, Larsen SW, Bair J, Utheim TP, Dartt DA, Heegaard S, Petrovski G, Kolko M (2021)
    Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops
    BMJ Open Ophthalmol, 6 (1), e000892
    DOI 10.1136/bmjophth-2021-000892, PubMed 34993350
  20. Olafsson J, Lai X, Landsend ECS, Olafsson S, Parissi E, Utheim ØA, Raeder S, Badian RA, Lagali N, Dartt DA, Utheim TP (2021)
    TheraPearl Eye Mask and Blephasteam for the treatment of meibomian gland dysfunction: a randomized, comparative clinical trial
    Sci Rep, 11 (1), 22386
    DOI 10.1038/s41598-021-01899-8, PubMed 34789807
  21. Rauner M, Foessl I, Formosa MM, Kague E, Prijatelj V, Lopez NA, Banerjee B, Bergen D, Busse B, Calado Â, Douni E, Gabet Y, Giralt NG, Grinberg D, Lovsin NM, Solan XN, Ostanek B, Pavlos NJ, Rivadeneira F, Soldatovic I, van de Peppel J, van der Eerden B, van Hul W, Balcells S, Marc J et al. (2021)
    Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques
    Front Endocrinol (Lausanne), 12, 731217
    DOI 10.3389/fendo.2021.731217, PubMed 34938269
  22. Smeringaiova I, Utheim TP, Jirsova K (2021)
    Ex vivo expansion and characterization of human corneal endothelium for transplantation: a review
    Stem Cell Res Ther, 12 (1), 554
    DOI 10.1186/s13287-021-02611-3, PubMed 34717745
  23. Storås AM, Strümke I, Riegler MA, Grauslund J, Hammer HL, Yazidi A, Halvorsen P, Gundersen KG, Utheim TP, Jackson CJ (2021)
    Artificial intelligence in dry eye disease
    Ocul Surf, 23, 74-86
    DOI 10.1016/j.jtos.2021.11.004, PubMed 34843999
  24. Tulek A, Mulic A, Hogset M, Utheim TP, Sehic A (2021)
    Therapeutic Strategies for Dry Mouth Management with Emphasis on Electrostimulation as a Treatment Option
    Int J Dent, 2021, 6043488
    DOI 10.1155/2021/6043488, PubMed 34691182
  25. Westgaard KL, Hynne H, Amdal CD, Young A, Singh PB, Chen X, Rykke M, Hove LH, Aqrawi LA, Utheim TP, Herlofson BB, Jensen JL (2021)
    Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
    Sci Rep, 11 (1), 4026
    DOI 10.1038/s41598-021-83635-w, PubMed 33597629
  26. Yang M, Botten N, Hodges R, Bair J, Utheim TP, Serhan CN, Dartt DA (2021)
    Resolvin D2 and Resolvin D1 Differentially Activate Protein Kinases to Counter-Regulate Histamine-Induced [Ca2+]i Increase and Mucin Secretion in Conjunctival Goblet Cells
    Int J Mol Sci, 23 (1)
    DOI 10.3390/ijms23010141, PubMed 35008563
  27. Yazdani M, Elgstøen KBP (2021)
    Is oxidative stress an overlooked player in pyridoxine-dependent epilepsy? A focused review
    Seizure, 91, 369-373
    DOI 10.1016/j.seizure.2021.07.014, PubMed 34298455
  28. Yazdani M, Elgstøen KBP, Utheim TP (2021)
    Eye Make-up Products and Dry Eye Disease: A Mini Review
    Curr Eye Res, 47 (1), 1-11
    DOI 10.1080/02713683.2021.1966476, PubMed 34365876
  29. Yazdani M, Fiskådal J, Chen X, Utheim ØA, Ræder S, Vitelli V, Utheim TP (2021)
    Tear Film Break-Up Time and Dry Eye Disease Severity in a Large Norwegian Cohort
    J Clin Med, 10 (4)
    DOI 10.3390/jcm10040884, PubMed 33671667

Publications 2020

  1. Aqrawi LA, Chen X, Hynne H, Amdal C, Reppe S, Aass HCD, Rykke M, Hove LH, Young A, Herlofson BB, Westgaard KL, Utheim TP, Galtung HK, Jensen JL (2020)
    Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways
    Cells, 9 (9)
    DOI 10.3390/cells9092050, PubMed 32911805
  2. Cabral JV, Jackson CJ, Utheim TP, Jirsova K (2020)
    Ex vivo cultivated oral mucosal epithelial cell transplantation for limbal stem cell deficiency: a review
    Stem Cell Res Ther, 11 (1), 301
    DOI 10.1186/s13287-020-01783-8, PubMed 32693830
  3. Enayati S, Chang K, Achour H, Cho KS, Xu F, Guo S, Z Enayati K, Xie J, Zhao E, Turunen T, Sehic A, Lu L, Utheim TP, Chen DF (2020)
    Electrical Stimulation Induces Retinal Müller Cell Proliferation and Their Progenitor Cell Potential
    Cells, 9 (3)
    DOI 10.3390/cells9030781, PubMed 32210151
  4. Fineide F, Arita R, Utheim TP (2020)
    The role of meibography in ocular surface diagnostics: A review
    Ocul Surf, 19, 133-144
    DOI 10.1016/j.jtos.2020.05.004, PubMed 32416235
  5. García-Posadas L, Hodges RR, Utheim TP, Olstad OK, Delcroix V, Makarenkova HP, Dartt DA (2020)
    Lacrimal Gland Myoepithelial Cells Are Altered in a Mouse Model of Dry Eye Disease
    Am J Pathol, 190 (10), 2067-2079
    DOI 10.1016/j.ajpath.2020.06.013, PubMed 32679229
  6. Gautvik KM, Günther CC, Prijatelj V, Medina-Gomez C, Shevroja E, Rad LH, Yazdani M, Lindalen E, Valland H, Gautvik VT, Olstad OK, Holden M, Rivadeneira F, Utheim TP, Reppe S (2020)
    Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone
    J Bone Miner Res, 35 (6), 1065-1076
    DOI 10.1002/jbmr.3974, PubMed 32017184
  7. Islam R, Corraya RM, Pasovic L, Khan AZ, Aass HCD, Eidet JR, Utheim TP (2020)
    The Effects of Prolonged Storage on ARPE-19 Cells Stored at Three Different Storage Temperatures
    Molecules, 25 (24)
    DOI 10.3390/molecules25245809, PubMed 33317020
  8. Jackson CJ, Pasovic L, Raeder S, Sehic A, Roald B, de la Paz MF, Tønseth KA, Utheim TP (2020)
    Optisol-GS Storage of Cultured Human Limbal Epithelial Cells at Ambient Temperature Is Superior to Hypothermic Storage
    Curr Eye Res, 45 (12), 1497-1503
    DOI 10.1080/02713683.2020.1770295, PubMed 32578462
  9. Jirsova K, Seidler Stangova P, Palos M, Mahelkova G, Kalasova S, Rybickova I, Utheim TP, Vesela V (2020)
    Aberrant HLA-DR expression in the conjunctival epithelium after autologous serum treatment in patients with graft-versus-host disease or Sjögren's syndrome
    PLoS One, 15 (4), e0231473
    DOI 10.1371/journal.pone.0231473, PubMed 32315325
  10. Khan AZ, Jackson CJ, Utheim TP, Reppe S, Sapkota D, Olstad OK, Thiede B, Eidet JR (2020)
    Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins
    Molecules, 25 (19)
    DOI 10.3390/molecules25194395, PubMed 32987810
  11. Khan AZ, Utheim TP, Moe MC, Aass HCD, Sapkota D, Vallenari EM, Eidet JR (2020)
    The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
    Curr Eye Res, 46 (4), 504-514
    DOI 10.1080/02713683.2020.1809001, PubMed 32777180
  12. Olsen MV, Lyngstadaas AV, Bair JA, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2020)
    Maresin 1, a specialized proresolving mediator, stimulates intracellular [Ca2+ ] and secretion in conjunctival goblet cells
    J Cell Physiol, 236 (1), 340-353
    DOI 10.1002/jcp.29846, PubMed 32510663
  13. Olsen MV, Lyngstadaas AV, Zhou W, Stojanovic A, Utheim TP, Wang X, Badian RA, Chen X (2020)
    Temporal redistribution of cap and residual stromal thickness after SMILE
    J Cataract Refract Surg, 46 (10), 1331-1338
    DOI 10.1097/j.jcrs.0000000000000242, PubMed 32398471
  14. Olstad OK, Gautvik VT, LeBlanc M, Kvernevik KJ, Utheim TP, Runningen A, Wiig H, Kirkegaard C, Raastad T, Reppe S, Gautvik KM (2020)
    Postmenopausal osteoporosis is a musculoskeletal disease with a common genetic trait which responds to strength training: a translational intervention study
    Ther Adv Musculoskelet Dis, 12, 1759720X20929443
    DOI 10.1177/1759720X20929443, PubMed 32536985
  15. Ringstad H, Reppe S, Schøyen TH, Tønseth KA, Utheim TP, Jackson CJ (2020)
    Stem cell function is conserved during short-term storage of cultured epidermal cell sheets at 12°C
    PLoS One, 15 (5), e0232270
    DOI 10.1371/journal.pone.0232270, PubMed 32433698
  16. Tashbayev B, Garen T, Palm Ø, Chen X, Herlofson BB, Young A, Hove LH, Rykke M, Singh PB, Aqrawi LA, Utheim ØA, Utheim TP, Jensen JL (2020)
    Patients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional study
    Sci Rep, 10 (1), 2063
    DOI 10.1038/s41598-020-59078-0, PubMed 32034249
  17. Tashbayev B, Utheim TP, Utheim ØA, Ræder S, Jensen JL, Yazdani M, Lagali N, Vitelli V, Dartt DA, Chen X (2020)
    Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease
    Sci Rep, 10 (1), 5542
    DOI 10.1038/s41598-020-62583-x, PubMed 32218518
  18. Tashbayev B, Yazdani M, Arita R, Fineide F, Utheim TP (2020)
    Intense pulsed light treatment in meibomian gland dysfunction: A concise review
    Ocul Surf, 18 (4), 583-594
    DOI 10.1016/j.jtos.2020.06.002, PubMed 32629039
  19. Tellefsen Nøland S, Badian RA, Utheim TP, Utheim ØA, Stojanovic A, Tashbayev B, Raeder S, Dartt DA, Chen X (2020)
    Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients
    Ocul Surf, 19, 68-73
    DOI 10.1016/j.jtos.2020.11.009, PubMed 33246035
  20. Tulek A, Mulic A, Refsholt Stenhagen K, Galtung HK, Saeed M, Utheim TP, Khuu C, Galteland P, Sehic A (2020)
    Dental erosion in mice with impaired salivary gland function
    Acta Odontol Scand, 78 (5), 390-400
    DOI 10.1080/00016357.2020.1734234, PubMed 32141357
  21. Yang M, Lippestad M, Hodges RR, Fjærvoll HK, Fjærvoll KA, Bair JA, Utheim TP, Serhan CN, Dartt DA (2020)
    RvE1 uses the LTB4 receptor BLT1 to increase [Ca2+]i and stimulate mucin secretion in cultured rat and human conjunctival goblet cells
    Ocul Surf, 18 (3), 470-482
    DOI 10.1016/j.jtos.2020.04.011, PubMed 32361084
  22. Yazdani M, Shahdadfar A, Reppe S, Sapkota D, Vallenari EM, Lako M, Connon CJ, Figueiredo FC, Utheim TP (2020)
    Response of human oral mucosal epithelial cells to different storage temperatures: A structural and transcriptional study
    PLoS One, 15 (12), e0243914
    DOI 10.1371/journal.pone.0243914, PubMed 33326470

Publications 2019

  1. Aqrawi LA, Galtung HK, Guerreiro EM, Øvstebø R, Thiede B, Utheim TP, Chen X, Utheim ØA, Palm Ø, Skarstein K, Jensen JL (2019)
    Proteomic and histopathological characterisation of sicca subjects and primary Sjögren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
    Arthritis Res Ther, 21 (1), 181
    DOI 10.1186/s13075-019-1961-4, PubMed 31366407
  2. Botten N, Hodges RR, Li D, Bair JA, Shatos MA, Utheim TP, Serhan CN, Dartt DA (2019)
    Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells
    FASEB J, 33 (7), 8468-8478
    DOI 10.1096/fj.201802467R, PubMed 31013438
  3. Chen X, Aqrawi LA, Utheim TP, Tashbayev B, Utheim ØA, Reppe S, Hove LH, Herlofson BB, Singh PB, Palm Ø, Galtung HK, Jensen JCL (2019)
    Elevated cytokine levels in tears and saliva of patients with primary Sjögren's syndrome correlate with clinical ocular and oral manifestations
    Sci Rep, 9 (1), 7319
    DOI 10.1038/s41598-019-43714-5, PubMed 31086200
  4. Hokstad I, Deyab G, Wang Fagerland M, Lyberg T, Hjeltnes G, Førre Ø, Agewall S, Mollnes TE, Hollan I (2019)
    Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
    PLoS One, 14 (7), e0220079
    DOI 10.1371/journal.pone.0220079, PubMed 31335881
  5. Hsu YH, Estrada K, Evangelou E, Ackert-Bicknell C, Akesson K, Beck T, Brown SJ, Capellini T, Carbone L, Cauley J, Cheung CL, Cummings SR, Czerwinski S, Demissie S, Econs M, Evans D, Farber C, Gautvik K, Harris T, Kammerer C, Kemp J, Koller DL, Kung A, Lawlor D, Lee M et al. (2019)
    Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry
    J Bone Miner Res, 34 (7), 1284-1296
    DOI 10.1002/jbmr.3698, PubMed 30888730
  6. Jackson CJ, Myklebust Ernø IT, Ringstad H, Tønseth KA, Dartt DA, Utheim TP (2019)
    Simple limbal epithelial transplantation: Current status and future perspectives
    Stem Cells Transl Med, 9 (3), 316-327
    DOI 10.1002/sctm.19-0203, PubMed 31802651
  7. Lagali N, Wowra B, Fries FN, Latta L, Moslemani K, Utheim TP, Wylegala E, Seitz B, Käsmann-Kellner B (2019)
    Early phenotypic features of aniridia-associated keratopathy and association with PAX6 coding mutations
    Ocul Surf, 18 (1), 130-140
    DOI 10.1016/j.jtos.2019.11.002, PubMed 31734509
  8. Landsend ECS, Pedersen HR, Utheim ØA, Rueegg CS, Baraas RC, Lagali N, Bragadóttir R, Moe MC, Utheim TP (2019)
    Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy
    Invest Ophthalmol Vis Sci, 60 (13), 4120-4128
    DOI 10.1167/iovs.19-26994, PubMed 31574536
  9. Raeder S, Klyve P, Utheim TP (2019)
    Dry eyes - diagnostics and treatment
    Tidsskr. Nor. Laegeforen., 139 (11), 1061-1064
  10. Stadnikova A, Trosan P, Skalicka P, Utheim TP, Jirsova K (2019)
    Interleukin-13 maintains the stemness of conjunctival epithelial cell cultures prepared from human limbal explants
    PLoS One, 14 (2), e0211861
    DOI 10.1371/journal.pone.0211861, PubMed 30742646
  11. Utheim OA, Pasovic L, Raeder S, Eidet JR, Fostad IG, Sehic A, Roald B, de la Paz MF, Lyberg T, Dartt DA, Utheim TP (2019)
    Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells
    PLoS One, 14 (3), e0212524
    DOI 10.1371/journal.pone.0212524, PubMed 30861002
  12. Xiao J, Adil MY, Chen X, Utheim ØA, Ræder S, Tønseth KA, Lagali NS, Dartt DA, Utheim TP (2019)
    Functional and Morphological Evaluation of Meibomian Glands in the Assessment of Meibomian Gland Dysfunction Subtype and Severity
    Am J Ophthalmol, 209, 160-167
    DOI 10.1016/j.ajo.2019.09.005, PubMed 31526799
  13. Yazdani M, Chen X, Tashbayev B, Utheim ØA, Ræder S, Hua Y, Eidet JR, Stojanovic A, Dartt DA, Utheim TP (2019)
    Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients
    Curr Eye Res, 44 (9), 941-947
    DOI 10.1080/02713683.2019.1604972, PubMed 30955380
  14. Yazdani M, Elgstøen KBP, Rootwelt H, Shahdadfar A, Utheim ØA, Utheim TP (2019)
    Tear Metabolomics in Dry Eye Disease: A Review
    Int J Mol Sci, 20 (15)
    DOI 10.3390/ijms20153755, PubMed 31374809
  15. Yazdani M, Shahdadfar A, Jackson CJ, Utheim TP (2019)
    Hyaluronan-Based Hydrogel Scaffolds for Limbal Stem Cell Transplantation: A Review
    Cells, 8 (3)
    DOI 10.3390/cells8030245, PubMed 30875861
  16. Yazdani M, Shahdadfar A, Jackson CJ, Utheim TP (2019)
    A Hyaluronan Hydrogel Scaffold for Culture of Human Oral Mucosal Epithelial Cells in Limbal Stem-Cell Therapy
    Bioengineering (Basel), 6 (4)
    DOI 10.3390/bioengineering6040097, PubMed 31652804
  17. Zheng J, Maerz W, Gergei I, Kleber M, Drechsler C, Wanner C, Brandenburg V, Reppe S, Gautvik KM, Medina-Gomez C, Shevroja E, Gilly A, Park YC, Dedoussis G, Zeggini E, Lorentzon M, Henning P, Lerner UH, Nilsson KH, Movérare-Skrtic S, Baird D, Elsworth B, Falk L, Groom A, Capellini TD et al. (2019)
    Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures
    J Bone Miner Res, 34 (10), 1824-1836
    DOI 10.1002/jbmr.3803, PubMed 31170332
  18. Zhou W, Reinstein DZ, Chen X, Chen S, Xu Y, Utheim TP, Stojanovic A (2019)
    Transepithelial Topography-Guided Ablation Assisted by Epithelial Thickness Mapping for Treatment of Regression After Myopic Refractive Surgery
    J Refract Surg, 35 (8), 525-533
    DOI 10.3928/1081597X-20190730-01, PubMed 31393991

Publications 2018

  1. Adil MY, Xiao J, Olafsson J, Chen X, Lagali NS, Ræder S, Utheim ØA, Dartt DA, Utheim TP (2018)
    Meibomian Gland Morphology Is a Sensitive Early Indicator of Meibomian Gland Dysfunction
    Am J Ophthalmol, 200, 16-25
    DOI 10.1016/j.ajo.2018.12.006, PubMed 30578784
  2. Aqrawi LA, Chen X, Jensen JL, Morthen MK, Thiede B, Utheim ØA, Palm Ø, Tashbayev B, Utheim TP, Galtung HK (2018)
    Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients with primary Sjögren's syndrome
    PLoS One, 13 (10), e0205762
    DOI 10.1371/journal.pone.0205762, PubMed 30312344
  3. Brejchova K, Trosan P, Studeny P, Skalicka P, Utheim TP, Bednar J, Jirsova K (2018)
    Characterization and comparison of human limbal explant cultures grown under defined and xeno-free conditions
    Exp Eye Res, 176, 20-28
    DOI 10.1016/j.exer.2018.06.019, PubMed 29928900
  4. Deyab G, Hokstad I, Aaseth J, Småstuen MC, Whist JE, Agewall S, Lyberg T, Tveiten D, Hjeltnes G, Zibara K, Hollan I (2018)
    Effect of anti-rheumatic treatment on selenium levels in inflammatory arthritis
    J Trace Elem Med Biol, 49, 91-97
    DOI 10.1016/j.jtemb.2018.05.001, PubMed 29895378
  5. Guo C, Cho KS, Li Y, Tchedre K, Antolik C, Ma J, Chew J, Utheim TP, Huang XA, Yu H, Malik MTA, Anzak N, Chen DF (2018)
    IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades
    Sci Rep, 8 (1), 2054
    DOI 10.1038/s41598-018-20463-5, PubMed 29391597
  6. He M, Lippestad M, Li D, Hodges RR, Utheim TP, Dartt DA (2018)
    Activation of the EGF Receptor by Histamine Receptor Subtypes Stimulates Mucin Secretion in Conjunctival Goblet Cells
    Invest Ophthalmol Vis Sci, 59 (8), 3543-3553
    DOI 10.1167/iovs.18-2476, PubMed 30025103
  7. Kaye R, Botten N, Lippestad M, Li D, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2018)
    Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells
    Exp Eye Res, 180, 53-62
    DOI 10.1016/j.exer.2018.11.018, PubMed 30513286
  8. Khan AZ, Utheim TP, Reppe S, Sandvik L, Lyberg T, Roald BB, Ibrahim IB, Eidet JR (2018)
    Cultured Human Retinal Pigment Epithelial (hRPE) Sheets: A Search for Suitable Storage Conditions
    Microsc Microanal, 24 (2), 147-155
    DOI 10.1017/S1431927618000144, PubMed 29637873
  9. Lagali NS, Allgeier S, Guimarães P, Badian RA, Ruggeri A, Köhler B, Utheim TP, Peebo B, Peterson M, Dahlin LB, Rolandsson O (2018)
    Wide-field corneal subbasal nerve plexus mosaics in age-controlled healthy and type 2 diabetes populations
    Sci Data, 5, 180075
    DOI 10.1038/sdata.2018.75, PubMed 29688226
  10. Lagali NS, Badian RA, Liu X, Feldreich TR, Ärnlöv J, Utheim TP, Dahlin LB, Rolandsson O (2018)
    Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9
    Sci Rep, 8 (1), 14248
    DOI 10.1038/s41598-018-32410-5, PubMed 30250206
  11. Landsend ECS, Pedersen HR, Utheim ØA, Xiao J, Adil MY, Tashbayev B, Lagali N, Dartt DA, Baraas RC, Utheim TP (2018)
    Meibomian gland dysfunction and keratopathy are associated with dry eye disease in aniridia
    Br J Ophthalmol, 103 (1), 119-124
    DOI 10.1136/bjophthalmol-2017-310927, PubMed 29519880
  12. Landsend ECS, Utheim ØA, Pedersen HR, Aass HCD, Lagali N, Dartt DA, Baraas RC, Utheim TP (2018)
    The Level of Inflammatory Tear Cytokines is Elevated in Congenital Aniridia and Associated with Meibomian Gland Dysfunction
    Invest Ophthalmol Vis Sci, 59 (5), 2197-2204
    DOI 10.1167/iovs.18-24027, PubMed 29801153
  13. Lien TG, Borgan Ø, Reppe S, Gautvik K, Glad IK (2018)
    Integrated analysis of DNA-methylation and gene expression using high-dimensional penalized regression: a cohort study on bone mineral density in postmenopausal women
    BMC Med Genomics, 11 (1), 24
    DOI 10.1186/s12920-018-0341-2, PubMed 29514638
  14. Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2018)
    Signaling pathways activated by resolvin E1 to stimulate mucin secretion and increase intracellular Ca2+ in cultured rat conjunctival goblet cells
    Exp Eye Res, 173, 64-72
    DOI 10.1016/j.exer.2018.04.015, PubMed 29702100
  15. Lång E, Połeć A, Lång A, Valk M, Blicher P, Rowe AD, Tønseth KA, Jackson CJ, Utheim TP, Janssen LMC, Eriksson J, Bøe SO (2018)
    Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
    Nat Commun, 9 (1), 3665
    DOI 10.1038/s41467-018-05578-7, PubMed 30202009
  16. Nirvani M, Khuu C, Tulek A, Utheim TP, Sand LP, Snead ML, Sehic A (2018)
    Transcriptomic analysis of MicroRNA expression in enamel-producing cells
    Gene, 688, 193-203
    DOI 10.1016/j.gene.2018.11.089, PubMed 30529249
  17. Oma I, Olstad OK, Andersen JK, Lyberg T, Molberg Ø, Fostad I, Wang Fagerland M, Almdahl SM, Rynning SE, Yndestad A, Aukrust P, Whist JE, Hollan I (2018)
    Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis
    PLoS One, 13 (8), e0202346
    DOI 10.1371/journal.pone.0202346, PubMed 30138371
  18. Pasovic L, Utheim TP, Reppe S, Khan AZ, Jackson CJ, Thiede B, Berg JP, Messelt EB, Eidet JR (2018)
    Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design
    Sci Rep, 8 (1), 5688
    DOI 10.1038/s41598-018-24121-8, PubMed 29632395
  19. Pedersen HR, Hagen LA, Landsend ECS, Gilson SJ, Utheim ØA, Utheim TP, Neitz M, Baraas RC (2018)
    Color Vision in Aniridia
    Invest Ophthalmol Vis Sci, 59 (5), 2142-2152
    DOI 10.1167/iovs.17-23047, PubMed 29801149
  20. Reppe S, Jackson CJ, Ringstad H, Tønseth KA, Bakke H, Eidet JR, Utheim TP (2018)
    High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets
    Stem Cells Int, 2018, 6545876
    DOI 10.1155/2018/6545876, PubMed 30581473
  21. Tulek A, Saeed M, Mulic A, Stenhagen KR, Utheim TP, Galtung HK, Khuu C, Nirvani M, Kristiansen MS, Sehic A (2018)
    New animal model of extrinsic dental erosion-Erosive effect on the mouse molar teeth
    Arch Oral Biol, 96, 137-145
    DOI 10.1016/j.archoralbio.2018.08.013, PubMed 30241000
  22. Utheim OA, Lyberg T, Eidet JR, Raeder S, Sehic A, Roald B, Messelt E, de la Paz MF, Dartt DA, Utheim TP (2018)
    Effect of Transportation on Cultured Limbal Epithelial Sheets for Worldwide Treatment of Limbal Stem Cell Deficiency
    Sci Rep, 8 (1), 10502
    DOI 10.1038/s41598-018-28553-0, PubMed 30002380
  23. Yazdani M (2018)
    Comparative toxicity of selected PAHs in rainbow trout hepatocytes: genotoxicity, oxidative stress and cytotoxicity
    Drug Chem Toxicol, 43 (1), 71-78
    DOI 10.1080/01480545.2018.1497054, PubMed 30246564
  24. Yazdani M, Chen X, Tashbayev B, Utheim ØA, Ræder S, Lagali N, Stojanovic A, Dartt DA, Utheim TP (2018)
    Tear Production Levels and Dry Eye Disease Severity in a Large Norwegian Cohort
    Curr Eye Res, 43 (12), 1465-1470
    DOI 10.1080/02713683.2018.1514055, PubMed 30183390
  25. Aabel P, Utheim TP, Olstad OK, Rask-Andersen H, Dilley RJ, von Unge M (2018)
    Transcription and microRNA Profiling of Cultured Human Tympanic Membrane Epidermal Keratinocytes
    J Assoc Res Otolaryngol, 19 (3), 243-260
    DOI 10.1007/s10162-018-0660-1, PubMed 29623476

Publications 2017

  1. Alonso N, Estrada K, Albagha OME, Herrera L, Reppe S, Olstad OK, Gautvik KM, Ryan NM, Evans KL, Nielson CM, Hsu YH, Kiel DP, Markozannes G, Ntzani EE, Evangelou E, Feenstra B, Liu X, Melbye M, Masi L, Brandi ML, Riches P, Daroszewska A, Olmos JM, Valero C, Castillo J et al. (2017)
    Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density
    Ann Rheum Dis, 77 (3), 378-385
    DOI 10.1136/annrheumdis-2017-212469, PubMed 29170203
  2. Aqrawi LA, Galtung HK, Vestad B, Øvstebø R, Thiede B, Rusthen S, Young A, Guerreiro EM, Utheim TP, Chen X, Utheim ØA, Palm Ø, Jensen JL (2017)
    Identification of potential saliva and tear biomarkers in primary Sjögren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
    Arthritis Res Ther, 19 (1), 14
    DOI 10.1186/s13075-017-1228-x, PubMed 28122643
  3. Chen X, Stojanovic A, Xu Y, Zhou W, Raeder S, Enayati S, Utheim TP (2017)
    Medium- to Long-Term Results of Corneal Cross-Linking for Keratoconus Using Phototherapeutic Keratectomy for Epithelial Removal and Partial Stromal Ablation
    J Refract Surg, 33 (7), 488-495
    DOI 10.3928/1081597X-20170504-03, PubMed 28681909
  4. Chen X, Utheim ØA, Xiao J, Adil MY, Stojanovic A, Tashbayev B, Jensen JL, Utheim TP (2017)
    Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome
    PLoS One, 12 (9), e0184284
    DOI 10.1371/journal.pone.0184284, PubMed 28886085
  5. Deyab G, Hokstad I, Whist JE, Smastuen MC, Agewall S, Lyberg T, Ronda N, Mikkelsen K, Hjeltnes G, Hollan I (2017)
    Methotrexate and anti-tumor necrosis factor treatment improves endothelial function in patients with inflammatory arthritis
    Arthritis Res Ther, 19 (1), 232
    DOI 10.1186/s13075-017-1439-1, PubMed 29041979
  6. Deyab G, Hokstad I, Whist JE, Småstuen MC, Agewall S, Lyberg T, Bottazzi B, Meroni PL, Leone R, Hjeltnes G, Hollan I (2017)
    Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
    PLoS One, 12 (2), e0169830
    DOI 10.1371/journal.pone.0169830, PubMed 28225768
  7. Islam R, Eidet JR, Badian RA, Lippestad M, Messelt E, Griffith M, Dartt DA, Utheim TP (2017)
    Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells
    Sci Rep, 7 (1), 674
    DOI 10.1038/s41598-017-00417-z, PubMed 28386069
  8. Jackson CJ, Reppe S, Eidet JR, Eide L, Tønseth KA, Bergersen LH, Dartt DA, Griffith M, Utheim TP (2017)
    Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets
    Sci Rep, 7 (1), 8206
    DOI 10.1038/s41598-017-08586-7, PubMed 28811665
  9. Jackson CJ, Tønseth KA, Utheim TP (2017)
    Cultured epidermal stem cells in regenerative medicine
    Stem Cell Res Ther, 8 (1), 155
    DOI 10.1186/s13287-017-0587-1, PubMed 28676094
  10. Karabegović I, Maas S, Medina-Gomez C, Zrimšek M, Reppe S, Gautvik KM, Uitterlinden AG, Rivadeneira F, Ghanbari M (2017)
    Genetic Polymorphism of miR-196a-2 is Associated with Bone Mineral Density (BMD)
    Int J Mol Sci, 18 (12)
    DOI 10.3390/ijms18122529, PubMed 29186852
  11. Lagali N, Wowra B, Dobrowolski D, Utheim TP, Fagerholm P, Wylegala E (2017)
    Stage-related central corneal epithelial transformation in congenital aniridia-associated keratopathy
    Ocul Surf, 16 (1), 163-172
    DOI 10.1016/j.jtos.2017.11.003, PubMed 29133179
  12. Lagali NS, Allgeier S, Guimarães P, Badian RA, Ruggeri A, Köhler B, Utheim TP, Peebo B, Peterson M, Dahlin LB, Rolandsson O (2017)
    Reduced Corneal Nerve Fiber Density in Type 2 Diabetes by Wide-Area Mosaic Analysis
    Invest Ophthalmol Vis Sci, 58 (14), 6318-6327
    DOI 10.1167/iovs.17-22257, PubMed 29242906
  13. Landsend ES, Utheim ØA, Pedersen HR, Lagali N, Baraas RC, Utheim TP (2017)
    The genetics of congenital aniridia-a guide for the ophthalmologist
    Surv Ophthalmol, 63 (1), 105-113
    DOI 10.1016/j.survophthal.2017.09.004, PubMed 28923585
  14. Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2017)
    Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways
    Invest Ophthalmol Vis Sci, 58 (11), 4530-4544
    DOI 10.1167/iovs.17-21914, PubMed 28892824
  15. Medina-Gomez C, Kemp JP, Dimou NL, Kreiner E, Chesi A, Zemel BS, Bønnelykke K, Boer CG, Ahluwalia TS, Bisgaard H, Evangelou E, Heppe DHM, Bonewald LF, Gorski JP, Ghanbari M, Demissie S, Duque G, Maurano MT, Kiel DP, Hsu YH, C J van der Eerden B, Ackert-Bicknell C, Reppe S, Gautvik KM, Raastad T et al. (2017)
    Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
    Nat Commun, 8 (1), 121
    DOI 10.1038/s41467-017-00108-3, PubMed 28743860
  16. Nirvani M, Khuu C, Utheim TP, Sand LP, Sehic A (2017)
    Circadian clock and oral cancer
    Mol Clin Oncol, 8 (2), 219-226
    DOI 10.3892/mco.2017.1518, PubMed 29435282
  17. Reppe S, Datta HK, Gautvik KM (2017)
    Omics analysis of human bone to identify genes and molecular networks regulating skeletal remodeling in health and disease
    Bone, 101, 88-95
    DOI 10.1016/j.bone.2017.04.012, PubMed 28450214
  18. Reppe S, Lien TG, Hsu YH, Gautvik VT, Olstad OK, Yu R, Bakke HG, Lyle R, Kringen MK, Glad IK, Gautvik KM (2017)
    Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
    Epigenetics, 12 (8), 674-687
    DOI 10.1080/15592294.2017.1345832, PubMed 28650214
  19. Shields KJ, Mollnes TE, Eidet JR, Mikkelsen K, Almdahl SM, Bottazzi B, Lyberg T, Manzi S, Ahearn JM, Hollan I (2017)
    Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases
    PLoS One, 12 (3), e0174577
    DOI 10.1371/journal.pone.0174577, PubMed 28362874
  20. Tashbayev B, Rusthen S, Young A, Herlofson BB, Hove LH, Singh PB, Rykke M, Aqrawi LA, Chen X, Utheim ØA, Utheim TP, Palm Ø, Jensen JL (2017)
    Interdisciplinary, Comprehensive Oral and Ocular Evaluation of Patients with Primary Sjögren's Syndrome
    Sci Rep, 7 (1), 10761
    DOI 10.1038/s41598-017-10809-w, PubMed 28883442

Publications 2016

  1. Chen X, Stojanovic A, Simonsen D, Wang X, Liu Y, Utheim TP (2016)
    Topography-Guided Transepithelial Surface Ablation in the Treatment of Moderate to High Astigmatism
    J Refract Surg, 32 (6), 418-25
    DOI 10.3928/1081597X-20160428-01, PubMed 27304606
  2. Chen X, Stojanovic A, Wang X, Liang J, Hu D, Utheim TP (2016)
    Epithelial Thickness Profile Change After Combined Topography-Guided Transepithelial Photorefractive Keratectomy and Corneal Cross-linking in Treatment of Keratoconus
    J Refract Surg, 32 (9), 626-34
    DOI 10.3928/1081597X-20160531-02, PubMed 27598733
  3. Eidet JR, Reppe S, Pasovic L, Olstad OK, Lyberg T, Khan AZ, Fostad IG, Chen DF, Utheim TP (2016)
    The Silk-protein Sericin Induces Rapid Melanization of Cultured Primary Human Retinal Pigment Epithelial Cells by Activating the NF-κB Pathway
    Sci Rep, 6, 22671
    DOI 10.1038/srep22671, PubMed 26940175
  4. Fostad IG, Eidet JR, Utheim TP, Ræder S, Lagali NS, Messelt EB, Dartt DA (2016)
    Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility
    PLoS One, 11 (5), e0155214
    DOI 10.1371/journal.pone.0155214, PubMed 27148875
  5. Hua Y, Zhang X, Utheim TP, Huang J, Pan C, Tan W, Wang Q (2016)
    Evaluation of Equivalent Keratometry Readings Obtained by Pentacam HR (High Resolution)
    PLoS One, 11 (3), e0150121
    DOI 10.1371/journal.pone.0150121, PubMed 26950834
  6. Khan AZ, Utheim TP, Jackson CJ, Reppe S, Lyberg T, Eidet JR (2016)
    Nucleus Morphometry in Cultured Epithelial Cells Correlates with Phenotype
    Microsc Microanal, 22 (3), 612-20
    DOI 10.1017/S1431927616000830, PubMed 27329312
  7. Khuu C, Nirvani M, Utheim TP, Sehic A (2016)
    MicroRNAs: Modulators of Tooth Development
    Microrna, 5 (2), 132-139
    DOI 10.2174/2211536605666160706003256, PubMed 27397033
  8. Khuu C, Utheim TP, Sehic A (2016)
    The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25
    Scientifica (Cairo), 2016, 1379643
    DOI 10.1155/2016/1379643, PubMed 27127675
  9. Kolko M, Vosborg F, Henriksen UL, Hasan-Olive MM, Diget EH, Vohra R, Gurubaran IR, Gjedde A, Mariga ST, Skytt DM, Utheim TP, Storm-Mathisen J, Bergersen LH (2016)
    Erratum to: Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease
    Neurochem Res, 41 (6), 1237
    DOI 10.1007/s11064-016-1916-y, PubMed 27113043
  10. Nielsen HG, Øktedalen O, Opstad PK, Lyberg T (2016)
    Plasma Cytokine Profiles in Long-Term Strenuous Exercise
    J Sports Med (Hindawi Publ Corp), 2016, 7186137
    DOI 10.1155/2016/7186137, PubMed 27239554
  11. Nielson CM, Liu CT, Smith AV, Ackert-Bicknell CL, Reppe S, Jakobsdottir J, Wassel C, Register TC, Oei L, Alonso N, Oei EH, Parimi N, Samelson EJ, Nalls MA, Zmuda J, Lang T, Bouxsein M, Latourelle J, Claussnitzer M, Siggeirsdottir K, Srikanth P, Lorentzen E, Vandenput L, Langefeld C, Raffield L et al. (2016)
    Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2
    J Bone Miner Res, 31 (12), 2085-2097
    DOI 10.1002/jbmr.2913, PubMed 27476799
  12. Nirvani M, Khuu C, Utheim TP, Hollingen HS, Amundsen SF, Sand LP, Sehic A (2016)
    Circadian rhythms and gene expression during mouse molar tooth development
    Acta Odontol Scand, 75 (2), 144-153
    DOI 10.1080/00016357.2016.1271999, PubMed 28030993
  13. Oma I, Andersen JK, Lyberg T, Molberg Ø, Whist JE, Fagerland MW, Almdahl SM, Hollan I (2016)
    Plasma vitamin D levels and inflammation in the aortic wall of patients with coronary artery disease with and without inflammatory rheumatic disease
    Scand J Rheumatol, 46 (3), 198-205
    DOI 10.3109/03009742.2016.1172664, PubMed 27379927
  14. Parissi M, Randjelovic S, Poletti E, Guimarães P, Ruggeri A, Fragkiskou S, Wihlmark TB, Utheim TP, Lagali N (2016)
    Corneal Nerve Regeneration After Collagen Cross-Linking Treatment of Keratoconus: A 5-Year Longitudinal Study
    JAMA Ophthalmol, 134 (1), 70-8
    DOI 10.1001/jamaophthalmol.2015.4518, PubMed 26562763
  15. Pasovic L, Eidet JR, Olstad OK, Chen DF, Lyberg T, Utheim TP (2016)
    Impact of Storage Temperature on the Expression of Cell Survival Genes in Cultured ARPE-19 Cells
    Curr Eye Res, 42 (1), 134-144
    DOI 10.3109/02713683.2016.1145236, PubMed 27259952
  16. Sehic A, Guo S, Cho KS, Corraya RM, Chen DF, Utheim TP (2016)
    Electrical Stimulation as a Means for Improving Vision
    Am J Pathol, 186 (11), 2783-2797
    DOI 10.1016/j.ajpath.2016.07.017, PubMed 27643530
  17. Sehic A, Tulek A, Khuu C, Nirvani M, Sand LP, Utheim TP (2016)
    Regulatory roles of microRNAs in human dental tissues
    Gene, 596, 9-18
    DOI 10.1016/j.gene.2016.10.009, PubMed 27725267
  18. Shatos MA, Hodges RR, Morinaga M, McNay DE, Islam R, Bhattacharya S, Li D, Turpie B, Makarenkova HP, Masli S, Utheim TP, Dartt DA (2016)
    Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1-/- mice, a model of dry eye
    Exp Eye Res, 153, 27-41
    DOI 10.1016/j.exer.2016.09.011, PubMed 27697548
  19. Tharmaratnam K, Sperrin M, Jaki T, Reppe S, Frigessi A (2016)
    Tilting the lasso by knowledge-based post-processing
    BMC Bioinformatics, 17 (1), 344
    DOI 10.1186/s12859-016-1210-7, PubMed 27590269
  20. Therkelsen SP, Hetland G, Lyberg T, Lygren I, Johnson E (2016)
    Effect of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan™, on Symptoms, Fatigue and Quality of Life in Patients with Ulcerative Colitis in a Randomized Single-Blinded Placebo Controlled Study
    PLoS One, 11 (3), e0150191
    DOI 10.1371/journal.pone.0150191, PubMed 26933886
  21. Therkelsen SP, Hetland G, Lyberg T, Lygren I, Johnson E (2016)
    Effect of the Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSanTM, on Symptoms, Fatigue and Quality of Life in Patients with Crohn's Disease in a Randomized Single-Blinded Placebo Controlled Study
    PLoS One, 11 (7), e0159288
    DOI 10.1371/journal.pone.0159288, PubMed 27415795
  22. Therkelsen SP, Hetland G, Lyberg T, Lygren I, Johnson E (2016)
    Cytokine Levels After Consumption of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan , in Patients with Crohn's Disease and Ulcerative Colitis in a Randomized Single-Blinded Placebo-Controlled Study
    Scand J Immunol, 84 (6), 323-331
    DOI 10.1111/sji.12476, PubMed 27588816
  23. Utheim TP, Islam R, Fostad IG, Eidet JR, Sehic A, Olstad OK, Dartt DA, Messelt EB, Griffith M, Pasovic L (2016)
    Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes
    PLoS One, 11 (3), e0152526
    DOI 10.1371/journal.pone.0152526, PubMed 27023475
  24. Utheim TP, Salvanos P, Utheim ØA, Ræder S, Pasovic L, Olstad OK, de la Paz MF, Sehic A (2016)
    Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
    J Funct Biomater, 7 (1)
    DOI 10.3390/jfb7010004, PubMed 26901233
  25. Utheim TP, Utheim ØA, Khan QE, Sehic A (2016)
    Culture of Oral Mucosal Epithelial Cells for the Purpose of Treating Limbal Stem Cell Deficiency
    J Funct Biomater, 7 (1)
    DOI 10.3390/jfb7010005, PubMed 26938569
  26. Zhou W, Stojanovic A, Utheim TP (2016)
    Assessment of refractive astigmatism and simulated therapeutic refractive surgery strategies in coma-like-aberrations-dominant corneal optics
    Eye Vis (Lond), 3, 13
    DOI 10.1186/s40662-016-0044-8, PubMed 27175371

Publications 2015

  1. Björkblom B, Eidet JR, Utheim TP, Ulltveit-Moe HF, Raeder S (2015)
    Xenobiotic- and Serum-Free Culture of Oral Mucosal Epithelial Cells on Contact Lenses
    Curr Eye Res, 41 (1), 20-7
    DOI 10.3109/02713683.2015.1004720, PubMed 25658020
  2. Chen X, Stojanovic A, Eidet JR, Utheim TP (2015)
    Corneal collagen cross-linking (CXL) in thin corneas
    Eye Vis (Lond), 2, 15
    DOI 10.1186/s40662-015-0025-3, PubMed 26605368
  3. Chen X, Stojanovic A, Liu Y, Chen Y, Zhou Y, Utheim TP (2015)
    Postoperative Changes in Corneal Epithelial and Stromal Thickness Profiles After Photorefractive Keratectomy in Treatment of Myopia
    J Refract Surg, 31 (7), 446-53
    DOI 10.3928/1081597X-20150623-02, PubMed 26186563
  4. Eidet JR, Dartt DA, Utheim TP (2015)
    Concise Review: Comparison of Culture Membranes Used for Tissue Engineered Conjunctival Epithelial Equivalents
    J Funct Biomater, 6 (4), 1064-84
    DOI 10.3390/jfb6041064, PubMed 26690486
  5. Hua Y, Stojanovic A, Utheim TP, Chen X, Ræder S, Huang J, Wang Q (2015)
    Keratometric index obtained by Fourier-domain optical coherence tomography
    PLoS One, 10 (4), e0122441
    DOI 10.1371/journal.pone.0122441, PubMed 25886489
  6. Islam R, Jackson C, Eidet JR, Messelt EB, Corraya RM, Lyberg T, Griffith M, Dartt DA, Utheim TP (2015)
    Effect of Storage Temperature on Structure and Function of Cultured Human Oral Keratinocytes
    PLoS One, 10 (6), e0128306
    DOI 10.1371/journal.pone.0128306, PubMed 26052937
  7. Jackson C, Eidet JR, Reppe S, Aass HC, Tønseth KA, Roald B, Lyberg T, Utheim TP (2015)
    Effect of Storage Temperature on the Phenotype of Cultured Epidermal Cells Stored in Xenobiotic-Free Medium
    Curr Eye Res, 41 (6), 757-68
    DOI 10.3109/02713683.2015.1062113, PubMed 26398483
  8. Kolko M, Vosborg F, Henriksen UL, Hasan-Olive MM, Diget EH, Vohra R, Gurubaran IR, Gjedde A, Mariga ST, Skytt DM, Utheim TP, Storm-Mathisen J, Bergersen LH (2015)
    Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease
    Neurochem Res, 41 (6), 1229-36
    DOI 10.1007/s11064-015-1792-x, PubMed 26677077
  9. Lagali N, Poletti E, Patel DV, McGhee CN, Hamrah P, Kheirkhah A, Tavakoli M, Petropoulos IN, Malik RA, Utheim TP, Zhivov A, Stachs O, Falke K, Peschel S, Guthoff R, Chao C, Golebiowski B, Stapleton F, Ruggeri A (2015)
    Focused Tortuosity Definitions Based on Expert Clinical Assessment of Corneal Subbasal Nerves
    Invest Ophthalmol Vis Sci, 56 (9), 5102-9
    DOI 10.1167/iovs.15-17284, PubMed 26241397
  10. LeBlanc M, Zuber V, Andreassen BK, Witoelar A, Zeng L, Bettella F, Wang Y, McEvoy LK, Thompson WK, Schork AJ, Reppe S, Barrett-Connor E, Ligthart S, Dehghan A, Gautvik KM, Nelson CP, Schunkert H, Samani NJ, CARDIoGRAM Consortium, Ridker PM, Chasman DI, Aukrust P, Djurovic S, Frigessi A, Desikan RS et al. (2015)
    Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
    Circ Res, 118 (1), 83-94
    DOI 10.1161/CIRCRESAHA.115.306629, PubMed 26487741
  11. Navaratnam J, Utheim TP, Rajasekhar VK, Shahdadfar A (2015)
    Substrates for Expansion of Corneal Endothelial Cells towards Bioengineering of Human Corneal Endothelium
    J Funct Biomater, 6 (3), 917-45
    DOI 10.3390/jfb6030917, PubMed 26378588
  12. Pasovic L, Eidet JR, Brusletto BS, Lyberg T, Utheim TP (2015)
    Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells
    J Ophthalmol, 2015, 263756
    DOI 10.1155/2015/263756, PubMed 26448872
  13. Reppe S, Datta H, Gautvik KM (2015)
    The Influence of DNA Methylation on Bone Cells
    Curr Genomics, 16 (6), 384-92
    DOI 10.2174/1389202916666150817202913, PubMed 27019613
  14. Reppe S, Noer A, Grimholt RM, Halldórsson BV, Medina-Gomez C, Gautvik VT, Olstad OK, Berg JP, Datta H, Estrada K, Hofman A, Uitterlinden AG, Rivadeneira F, Lyle R, Collas P, Gautvik KM (2015)
    Methylation of bone SOST, its mRNA, and serum sclerostin levels correlate strongly with fracture risk in postmenopausal women
    J Bone Miner Res, 30 (2), 249-56
    DOI 10.1002/jbmr.2342, PubMed 25155887
  15. Reppe S, Wang Y, Thompson WK, McEvoy LK, Schork AJ, Zuber V, LeBlanc M, Bettella F, Mills IG, Desikan RS, Djurovic S, Gautvik KM, Dale AM, Andreassen OA, GEFOS Consortium (2015)
    Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci
    PLoS One, 10 (12), e0144531
    DOI 10.1371/journal.pone.0144531, PubMed 26695485
  16. Salvanos P, Utheim TP, Moe MC, Eide N, Bragadόttir R (2015)
    Autofluorescence imaging in the differential diagnosis of optic disc melanocytoma
    Acta Ophthalmol, 93 (5), 476-480
    DOI 10.1111/aos.12725, PubMed 25923254
  17. Sehic A, Utheim ØA, Ommundsen K, Utheim TP (2015)
    Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
    J Funct Biomater, 6 (3), 863-88
    DOI 10.3390/jfb6030863, PubMed 26343740
  18. Utheim O, Islam R, Lyberg T, Roald B, Eidet JR, de la Paz MF, Dartt DA, Raeder S, Utheim TP (2015)
    Serum-free and xenobiotic-free preservation of cultured human limbal epithelial cells
    PLoS One, 10 (3), e0118517
    DOI 10.1371/journal.pone.0118517, PubMed 25734654
  19. Utheim TP (2015)
    Concise review: transplantation of cultured oral mucosal epithelial cells for treating limbal stem cell deficiency-current status and future perspectives
    Stem Cells, 33 (6), 1685-95
    DOI 10.1002/stem.1999, PubMed 25786664

Publications 2014

  1. Andreassen OA, McEvoy LK, Thompson WK, Wang Y, Reppe S, Schork AJ, Zuber V, Barrett-Connor E, Gautvik K, Aukrust P, Karlsen TH, Djurovic S, Desikan RS, Dale AM, International Consortium for Blood Pressure Genome-Wide Association Studies, Genetic Factors for Osteoporosis Consortium (2014)
    Identifying common genetic variants in blood pressure due to polygenic pleiotropy with associated phenotypes
    Hypertension, 63 (4), 819-26
    DOI 10.1161/HYPERTENSIONAHA.113.02077, PubMed 24396023
  2. Aspelin T, Eriksen M, Ilebekk A, Cataliotti A, Carlson CR, Lyberg T (2014)
    β-blockade abolishes the augmented cardiac tPA release induced by transactivation of heterodimerised bradykinin receptor-2 and β2-adrenergic receptor in vivo
    Thromb Haemost, 112 (5), 951-9
    DOI 10.1160/TH14-01-0059, PubMed 25078038
  3. Chen X, Stojanovic A, Hua Y, Eidet JR, Hu D, Wang J, Utheim TP (2014)
    Reliability of corneal dynamic scheimpflug analyser measurements in virgin and post-PRK eyes
    PLoS One, 9 (10), e109577
    DOI 10.1371/journal.pone.0109577, PubMed 25302580
  4. Eidet JR, Pasovic L, Maria R, Jackson CJ, Utheim TP (2014)
    Objective assessment of changes in nuclear morphology and cell distribution following induction of apoptosis
    Diagn Pathol, 9, 92
    DOI 10.1186/1746-1596-9-92, PubMed 24885713
  5. Eidet JR, Utheim ØA, Islam R, Lyberg T, Messelt EB, Dartt DA, Utheim TP (2014)
    The impact of storage temperature on the morphology, viability, cell number and metabolism of cultured human conjunctival epithelium
    Curr Eye Res, 40 (1), 30-9
    DOI 10.3109/02713683.2014.909497, PubMed 24750037
  6. Jackson C, Aabel P, Eidet JR, Messelt EB, Lyberg T, von Unge M, Utheim TP (2014)
    Effect of storage temperature on cultured epidermal cell sheets stored in xenobiotic-free medium
    PLoS One, 9 (8), e105808
    DOI 10.1371/journal.pone.0105808, PubMed 25170754
  7. Kemp JP, Medina-Gomez C, Estrada K, St Pourcain B, Heppe DH, Warrington NM, Oei L, Ring SM, Kruithof CJ, Timpson NJ, Wolber LE, Reppe S, Gautvik K, Grundberg E, Ge B, van der Eerden B, van de Peppel J, Hibbs MA, Ackert-Bicknell CL, Choi K, Koller DL, Econs MJ, Williams FM, Foroud T, Zillikens MC et al. (2014)
    Phenotypic dissection of bone mineral density reveals skeletal site specificity and facilitates the identification of novel loci in the genetic regulation of bone mass attainment
    PLoS Genet, 10 (6), e1004423
    DOI 10.1371/journal.pgen.1004423, PubMed 24945404
  8. Pasovic L, Eidet JR, Lyberg T, Messelt EB, Aabel P, Utheim TP (2014)
    Antioxidants Improve the Viability of Stored Adult Retinal Pigment Epithelial-19 Cultures
    Ophthalmol Ther, 3 (1-2), 49-61
    DOI 10.1007/s40123-014-0024-9, PubMed 25134496
  9. Riksen EA, Landin MA, Reppe S, Nakamura Y, Lyngstadaas SP, Reseland JE (2014)
    Enamel matrix derivative promote primary human pulp cell differentiation and mineralization
    Int J Mol Sci, 15 (5), 7731-49
    DOI 10.3390/ijms15057731, PubMed 24857913
  10. Stojanovic A, Zhou W, Utheim TP (2014)
    Corneal collagen cross-linking with and without epithelial removal: a contralateral study with 0.5% hypotonic riboflavin solution
    Biomed Res Int, 2014, 619398
    DOI 10.1155/2014/619398, PubMed 25050368

Publications 2013

  1. Edén U, Lagali N, Dellby A, Utheim TP, Riise R, Chen X, Fagerholm P (2013)
    Cataract development in Norwegian patients with congenital aniridia
    Acta Ophthalmol, 92 (2), e165-7
    DOI 10.1111/aos.12225, PubMed 23826968
  2. Engelsvold DH, Utheim TP, Olstad OK, Gonzalez P, Eidet JR, Lyberg T, Trøseid AM, Dartt DA, Raeder S (2013)
    miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium
    Exp Eye Res, 115, 189-98
    DOI 10.1016/j.exer.2013.07.003, PubMed 23872359
  3. Hjeltnes G, Hollan I, Førre O, Wiik A, Lyberg T, Mikkelsen K, Agewall S (2013)
    Serum levels of lipoprotein(a) and E-selectin are reduced in rheumatoid arthritis patients treated with methotrexate or methotrexate in combination with TNF-α-inhibitor
    Clin Exp Rheumatol, 31 (3), 415-21
    PubMed 23465067
  4. Lagali N, Edén U, Utheim TP, Chen X, Riise R, Dellby A, Fagerholm P (2013)
    In vivo morphology of the limbal palisades of vogt correlates with progressive stem cell deficiency in aniridia-related keratopathy
    Invest Ophthalmol Vis Sci, 54 (8), 5333-42
    DOI 10.1167/iovs.13-11780, PubMed 23860752
  5. Liu Y, Yang X, Utheim TP, Guo C, Xiao M, Liu Y, Yin Z, Ma J (2013)
    Correlation of cytokine levels and microglial cell infiltration during retinal degeneration in RCS rats
    PLoS One, 8 (12), e82061
    DOI 10.1371/journal.pone.0082061, PubMed 24349184
  6. Parissi M, Karanis G, Randjelovic S, Germundsson J, Poletti E, Ruggeri A, Utheim TP, Lagali N (2013)
    Standardized baseline human corneal subbasal nerve density for clinical investigations with laser-scanning in vivo confocal microscopy
    Invest Ophthalmol Vis Sci, 54 (10), 7091-102
    DOI 10.1167/iovs.13-12999, PubMed 24084094
  7. Pasovic L, Utheim TP, Maria R, Lyberg T, Messelt EB, Aabel P, Chen DF, Chen X, Eidet JR (2013)
    Optimization of Storage Temperature for Cultured ARPE-19 Cells
    J Ophthalmol, 2013, 216359
    DOI 10.1155/2013/216359, PubMed 24251032
  8. Stojanovic A, Chen S, Chen X, Stojanovic F, Zhang J, Zhang T, Utheim TP (2013)
    One-step transepithelial topography-guided ablation in the treatment of myopic astigmatism
    PLoS One, 8 (6), e66618
    DOI 10.1371/journal.pone.0066618, PubMed 23799124
  9. Utheim TP (2013)
    Limbal epithelial cell therapy: past, present, and future
    Methods Mol Biol, 1014, 3-43
    DOI 10.1007/978-1-62703-432-6_1, PubMed 23690002
  10. Utheim TP, Lyberg T, Ræder S (2013)
    The culture of limbal epithelial cells
    Methods Mol Biol, 1014, 103-29
    DOI 10.1007/978-1-62703-432-6_7, PubMed 23690008

Publications 2012

  1. Amundsen EK, Henriksson CE, Holthe MR, Urdal P (2012)
    Is the blood basophil count sufficiently precise, accurate, and specific?: three automated hematology instruments and flow cytometry compared
    Am J Clin Pathol, 137 (1), 86-92
    DOI 10.1309/AJCP19BFTHYTMORO, PubMed 22180481
  2. Amundsen EK, Urdal P, Hagve TA, Holthe MR, Henriksson CE (2012)
    Absolute neutrophil counts from automated hematology instruments are accurate and precise even at very low levels
    Am J Clin Pathol, 137 (6), 862-9
    DOI 10.1309/AJCPOJN03GOXZRZY, PubMed 22586044
  3. Aspelin T, Eriksen M, Ilebekk A, Björkman JA, Lyberg T (2012)
    Different cardiac tissue plasminogen activator release patterns by local stimulation of the endothelium and sympathetic nerves in pigs
    Blood Coagul Fibrinolysis, 23 (8), 714-22
    DOI 10.1097/MBC.0b013e328357d388, PubMed 22964765
  4. Eidet JR, Fostad IG, Shatos MA, Utheim TP, Utheim ØA, Raeder S, Dartt DA (2012)
    Effect of biopsy location and size on proliferative capacity of ex vivo expanded conjunctival tissue
    Invest Ophthalmol Vis Sci, 53 (6), 2897-903
    DOI 10.1167/iovs.11-8269, PubMed 22491407
  5. Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ et al. (2012)
    Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
    Nat Genet, 44 (5), 491-501
    DOI 10.1038/ng.2249, PubMed 22504420
  6. Fostad IG, Eidet JR, Shatos MA, Utheim TP, Utheim OA, Raeder S, Dartt DA (2012)
    Biopsy harvesting site and distance from the explant affect conjunctival epithelial phenotype ex vivo
    Exp Eye Res, 104, 15-25
    DOI 10.1016/j.exer.2012.09.007, PubMed 23022405
  7. Hjeltnes G, Hollan I, Førre Ø, Wiik A, Lyberg T, Mikkelsen K, Agewall S (2012)
    Endothelial function improves within 6 weeks of treatment with methotrexate or methotrexate in combination with a TNF-α inhibitor in rheumatoid arthritis patients
    Scand J Rheumatol, 41 (3), 240-2
    DOI 10.3109/03009742.2012.656698, PubMed 22401496
  8. Hjeltnes G, Hollan I, Førre Ø, Wiik A, Lyberg T, Mikkelsen K, Agewall S (2012)
    Relations of serum COMP to cardiovascular risk factors and endothelial function in patients with rheumatoid arthritis treated with methotrexate and TNF-α inhibitors
    J Rheumatol, 39 (7), 1341-7
    DOI 10.3899/jrheum.111401, PubMed 22660798
  9. Husebye EE, Lyberg T, Opdahl H, Aspelin T, Støen RO, Madsen JE, Røise O (2012)
    Intramedullary nailing of femoral shaft fractures in polytraumatized patients. a longitudinal, prospective and observational study of the procedure-related impact on cardiopulmonary- and inflammatory responses
    Scand J Trauma Resusc Emerg Med, 20, 2
    DOI 10.1186/1757-7241-20-2, PubMed 22221511
  10. Johnson E, Førland DT, Hetland G, Sætre L, Olstad OK, Lyberg T (2012)
    Effect of AndoSan™ on expression of adhesion molecules and production of reactive oxygen species in human monocytes and granulocytes in vivo
    Scand J Gastroenterol, 47 (8-9), 984-92
    DOI 10.3109/00365521.2012.660544, PubMed 22564240
  11. Medina-Gomez C, Kemp JP, Estrada K, Eriksson J, Liu J, Reppe S, Evans DM, Heppe DH, Vandenput L, Herrera L, Ring SM, Kruithof CJ, Timpson NJ, Zillikens MC, Olstad OK, Zheng HF, Richards JB, St Pourcain B, Hofman A, Jaddoe VW, Smith GD, Lorentzon M, Gautvik KM, Uitterlinden AG, Brommage R et al. (2012)
    Meta-analysis of genome-wide scans for total body BMD in children and adults reveals allelic heterogeneity and age-specific effects at the WNT16 locus
    PLoS Genet, 8 (7), e1002718
    DOI 10.1371/journal.pgen.1002718, PubMed 22792070
  12. Reppe S, Sachse D, Olstad OK, Gautvik VT, Sanderson P, Datta HK, Berg JP, Gautvik KM (2012)
    Identification of transcriptional macromolecular associations in human bone using browser based in silico analysis in a giant correlation matrix
    Bone, 53 (1), 69-78
    DOI 10.1016/j.bone.2012.11.015, PubMed 23195995

Publications 2011

  1. Ahlfors EE, Dahl JE, Lyberg T (2011)
    The development of T cell-dominated inflammatory responses induced by sodium lauryl sulphate in mouse oral mucosa
    Arch Oral Biol, 57 (6), 796-804
    DOI 10.1016/j.archoralbio.2011.11.005, PubMed 22153318
  2. Chen X, Stojanovic A, Zhou W, Utheim TP, Stojanovic F, Wang Q (2011)
    Transepithelial, Topography-guided Ablation in the Treatment of Visual Disturbances in LASIK Flap or Interface Complications
    J Refract Surg, 28 (2), 120-6
    DOI 10.3928/1081597X-20110926-01, PubMed 21974725
  3. Eidet JR, Utheim OA, Raeder S, Dartt DA, Lyberg T, Carreras E, Huynh TT, Messelt EB, Louch WE, Roald B, Utheim TP (2011)
    Effects of serum-free storage on morphology, phenotype, and viability of ex vivo cultured human conjunctival epithelium
    Exp Eye Res, 94 (1), 109-16
    DOI 10.1016/j.exer.2011.11.015, PubMed 22154551
  4. Hetland G, Johnson E, Lyberg T, Kvalheim G (2011)
    The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation
    Adv Pharmacol Sci, 2011, 157015
    DOI 10.1155/2011/157015, PubMed 21912538
  5. Jemtland R, Holden M, Reppe S, Olstad OK, Reinholt FP, Gautvik VT, Refvem H, Frigessi A, Houston B, Gautvik KM (2011)
    Molecular disease map of bone characterizing the postmenopausal osteoporosis phenotype
    J Bone Miner Res, 26 (8), 1793-801
    DOI 10.1002/jbmr.396, PubMed 21452281
  6. Vetlesen A, Holme PA, Lyberg T, Kjeldsen-Kragh J (2011)
    Recovery, survival, and function of transfused platelets and detection of platelet engraftment after allogeneic stem cell transplantation
    Transfusion, 52 (6), 1321-32
    DOI 10.1111/j.1537-2995.2011.03442.x, PubMed 22084943

Publications 2010

  1. Fortunati D, Reppe S, Fjeldheim AK, Nielsen M, Gautvik VT, Gautvik KM (2010)
    Periostin is a collagen associated bone matrix protein regulated by parathyroid hormone
    Matrix Biol, 29 (7), 594-601
    DOI 10.1016/j.matbio.2010.07.001, PubMed 20654714
  2. Varanasi SS, Olstad OK, Swan DC, Sanderson P, Gautvik VT, Reppe S, Francis RM, Gautvik KM, Datta HK (2010)
    Skeletal site-related variation in human trabecular bone transcriptome and signaling
    PLoS One, 5 (5), e10692
    DOI 10.1371/journal.pone.0010692, PubMed 20502692

Publications 2007

  1. Nissen-Meyer LS, Jemtland R, Gautvik VT, Pedersen ME, Paro R, Fortunati D, Pierroz DD, Stadelmann VA, Reppe S, Reinholt FP, Del Fattore A, Rucci N, Teti A, Ferrari S, Gautvik KM (2007)
    Osteopenia, decreased bone formation and impaired osteoblast development in Sox4 heterozygous mice
    J Cell Sci, 120 (Pt 16), 2785-95
    DOI 10.1242/jcs.003855, PubMed 17652162
  2. Nissen-Meyer LS, Svalheim S, Taubøll E, Reppe S, Lekva T, Solberg LB, Melhus G, Reinholt FP, Gjerstad L, Jemtland R (2007)
    Levetiracetam, phenytoin, and valproate act differently on rat bone mass, structure, and metabolism
    Epilepsia, 48 (10), 1850-60
    DOI 10.1111/j.1528-1167.2007.01176.x, PubMed 17634065

Publications 2006

  1. Reseland JE, Reppe S, Larsen AM, Berner HS, Reinholt FP, Gautvik KM, Slaby I, Lyngstadaas SP (2006)
    The effect of enamel matrix derivative on gene expression in osteoblasts
    Eur J Oral Sci, 114 Suppl 1, 205-11; discussion 254-6, 381-2
    DOI 10.1111/j.1600-0722.2006.00333.x, PubMed 16674687

Publications 2005

  1. Fjeldheim AK, Høvring PI, Løseth OP, Johansen PW, Glover JC, Matre V, Olstad OK, Reppe S, Gordeladze JO, Walaas SI, Gautvik KM (2005)
    Thyrotrophin-releasing hormone receptor 1 and prothyrotrophin-releasing hormone mRNA expression in the central nervous system are regulated by suckling in lactating rats
    Eur J Endocrinol, 152 (5), 791-803
    DOI 10.1530/eje.1.01902, PubMed 15879366

Publications 2003

  1. Olstad OK, Gautvik VT, Reppe S, Rian E, Jemtland R, Ohlsson C, Bruland OS, Gautvik KM (2003)
    Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning
    Anticancer Res, 23 (3B), 2201-16
    PubMed 12894494