Publications published since 2000 from OUS - Regenerative Medicine Unit
203 publications found
Publications 2021
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Meibomian gland dysfunction is highly prevalent among first-time visitors at a Norwegian dry eye specialist clinic
Sci Rep, 11 (1), 23412
DOI 10.1038/s41598-021-02738-6 -
Non-invasive electrical stimulation as a potential treatment for retinal degenerative diseases
Neural Regen. Res., 16 (8), 1558-1559
DOI 10.4103/1673-5374.303015 -
Alterations in meibomian glands in patients treated with intensity-modulated radiotherapy for head and neck cancer
Sci Rep, 11 (1), 22419
DOI 10.1038/s41598-021-01844-9 -
The role of meibography in ocular surface diagnostics: A review
Ocul. Surf., 19, 133-144
DOI 10.1016/j.jtos.2020.05.004 -
Characterization of Lipids in Saliva, Tears and Minor Salivary Glands of Sjogren's Syndrome Patients Using an HPLC/MS-Based Approach
Int. J. Mol. Sci., 22 (16), 8997
DOI 10.3390/ijms22168997 -
The association between visual display terminal use and dry eye: a review
Acta Ophthalmol.
DOI 10.1111/aos.15049 -
Perturbation of astroglial Slc38 glutamine transporters by NH4 (+) contributes to neurophysiologic manifestations in acute liver failure
Faseb J., 35 (7), e21588
DOI 10.1096/fj.202001712RR -
NF-kappa B activation in retinal microglia is involved in the inflammatory and neovascularization signaling in laser-induced choroidal neovascularization
Exp. Cell Res., 403 (1), 112581
DOI 10.1016/j.yexcr.2021.112581 -
Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells
Front. Med., 8, 686774
DOI 10.3389/fmed.2021.686774 -
Concise Review: Considering Optimal Temperature for Short-Term Storage of Epithelial Cells (vol 8, 686774, 2021)
Front. Med., 8, 775351
DOI 10.3389/fmed.2021.775351 -
The Silk Protein Sericin Promotes Viability of ARPE-19 and Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells in vitro
Curr. Eye Res., 46 (4), 504-514
DOI 10.1080/02713683.2020.1809001 -
Congenital aniridia - A comprehensive review of clinical features and therapeutic approaches
Surv. Ophthalmol., 66 (6), 1031-1050
DOI 10.1016/j.survophthal.2021.02.011 -
Pro-Resolving Mediator Annexin A1 Regulates Intracellular Ca2+ and Mucin Secretion in Cultured Goblet Cells Suggesting a New Use in Inflammatory Conjunctival Diseases
Front. Immunol., 12, 618653
DOI 10.3389/fimmu.2021.618653 -
Intraductal meibomian gland probing and its efficacy in the treatment of meibomian gland dysfunction
Surv. Ophthalmol., 66 (4), 612-622
DOI 10.1016/j.survophthal.2020.11.005 -
Chambered warm moist air eyelid warming devices - a review
Acta Ophthalmol.
DOI 10.1111/aos.15052 -
Lipocalin 2 serum levels correlate with age and bone turnover biomarkers in healthy subjects but not in postmenopausal osteoporotic women
Bone Rep., 14, 101059
DOI 10.1016/j.bonr.2021.101059 -
Impact of benzalkonium chloride-preserved and preservative-free latanoprost eye drops on cultured human conjunctival goblet cells upon acute exposure and differences in physicochemical properties of the eye drops
BMJ Open Ophthalmol., 6 (1), e000892
DOI 10.1136/bmjophth-2021-000892 -
Sex and age differences in symptoms and signs of dry eye disease in a Norwegian cohort of patients
Ocul. Surf., 19, 68-73
DOI 10.1016/j.jtos.2020.11.009 -
TheraPearl Eye Mask and Blephasteam for the treatment of meibomian gland dysfunction: a randomized, comparative clinical trial
Sci Rep, 11 (1), 22386
DOI 10.1038/s41598-021-01899-8 -
Maresin 1, a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion in conjunctival goblet cells
J. Cell. Physiol., 236 (1), 340-353
DOI 10.1002/jcp.29846 -
Perspective of the GEMSTONE Consortium on Current and Future Approaches to Functional Validation for Skeletal Genetic Disease Using Cellular, Molecular and Animal-Modeling Techniques
Front. Endocrinol., 12, 731217
DOI 10.3389/fendo.2021.731217 -
A pioneer study on human 3-nitropropionic acid intoxication: Contributions from metabolomics
J. Appl. Toxicol.
DOI 10.1002/jat.4259 -
Therapeutic Strategies for Dry Mouth Management with Emphasis on Electrostimulation as a Treatment Option
Int. J. Dent., 2021, 6043488
DOI 10.1155/2021/6043488 -
Oral and ocular late effects in head and neck cancer patients treated with radiotherapy
Sci Rep, 11 (1), 4026
DOI 10.1038/s41598-021-83635-w -
Is oxidative stress an overlooked player in pyridoxine-dependent epilepsy? A focused review
Seizure, 91, 369-373
DOI 10.1016/j.seizure.2021.07.014 -
Eye Make-up Products and Dry Eye Disease: A Mini Review
Curr. Eye Res.
DOI 10.1080/02713683.2021.1966476 -
Tear Film Break-Up Time and Dry Eye Disease Severity in a Large Norwegian Cohort
J. Clin. Med., 10 (4), 884
DOI 10.3390/jcm10040884
Publications 2020
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Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways
Cells, 9 (9), 2050
DOI 10.3390/cells9092050 -
Ex vivo cultivated oral mucosal epithelial cell transplantation for limbal stem cell deficiency: a review
Stem Cell Res. Ther., 11 (1), 301
DOI 10.1186/s13287-020-01783-8 -
Electrical Stimulation Induces Retinal Muller Cell Proliferation and Their Progenitor Cell Potential
Cells, 9 (3), 781
DOI 10.3390/cells9030781 -
Lacrimal Gland Myoepithelial Cells Are Altered in a Mouse Model of Dry Eye Disease
Am. J. Pathol., 190 (10), 2067-2079
DOI 10.1016/j.ajpath.2020.06.013 -
Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone
J. Bone Miner. Res., 35 (6), 1065-1076
DOI 10.1002/jbmr.3974 -
The Effects of Prolonged Storage on ARPE-19 Cells Stored at Three Different Storage Temperatures
Molecules, 25 (24), 5809
DOI 10.3390/molecules25245809 -
Simple limbal epithelial transplantation: Current status and future perspectives: Concise review
Stem Cells Transl. Med., 9 (3), 316-327
DOI 10.1002/sctm.19-0203 -
Optisol-GS Storage of Cultured Human Limbal Epithelial Cells at Ambient Temperature Is Superior to Hypothermic Storage
Curr. Eye Res., 45 (12), 1497-1503
DOI 10.1080/02713683.2020.1770295 -
Aberrant HLA-DR expression in the conjunctival epithelium after autologous serum treatment in patients with graft-versus-host disease or Sjogren's syndrome
PLoS One, 15 (4), e0231473
DOI 10.1371/journal.pone.0231473 -
Sericin-Induced Melanogenesis in Cultured Retinal Pigment Epithelial Cells Is Associated with Elevated Levels of Hydrogen Peroxide and Inflammatory Proteins
Molecules, 25 (19), 4395
DOI 10.3390/molecules25194395 -
Early phenotypic features of aniridia-associated keratopathy and association with PAX6 coding mutations
Ocul. Surf., 18 (1), 130-140
DOI 10.1016/j.jtos.2019.11.002 -
Temporal redistribution of cap and residual stromal thickness after SMILE
J. Cataract. Refract. Surg., 46 (10), 1331-1338
DOI 10.1097/j.jcrs.0000000000000242 -
Postmenopausal osteoporosis is a musculoskeletal disease with a common genetic trait which responds to strength training: a translational intervention study
Ther. Adv. Musculoskelet. Dis., 12, 1759720X20929443
DOI 10.1177/1759720X20929443 -
Stem cell function is conserved during short-term storage of cultured epidermal cell sheets at 12 degrees C
PLoS One, 15 (5), e0232270
DOI 10.1371/journal.pone.0232270 -
Povidone iodine treatment is deleterious to human ocular surface conjunctival cells in culture
BMJ Open Ophthalmol., 5 (1), e000545
DOI 10.1136/bmjophth-2020-000545 -
Patients with non-Sjogren's sicca report poorer general and oral health-related quality of life than patients with Sjogren's syndrome: a cross-sectional study
Sci Rep, 10 (1), 2063
DOI 10.1038/s41598-020-59078-0 -
Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease
Sci Rep, 10 (1), 5542
DOI 10.1038/s41598-020-62583-x -
Intense pulsed light treatment in meibomian gland dysfunction: A concise review
Ocul. Surf., 18 (4), 583-594
DOI 10.1016/j.jtos.2020.06.002 -
Dental erosion in mice with impaired salivary gland function
Acta Odontol. Scand., 78 (5), 390-400
DOI 10.1080/00016357.2020.1734234 -
Functional and Morphological Evaluation of Meibomian Glands in the Assessment of Meibomian Gland Dysfunction Subtype and Severity
Am. J. Ophthalmol., 209, 160-167
DOI 10.1016/j.ajo.2019.09.005 -
RvE1 uses the LTB4 receptor BLT1 to increase [Ca2+](i) and stimulate mucin secretion in cultured rat and human conjunctival goblet cells
Ocul. Surf., 18 (3), 470-482
DOI 10.1016/j.jtos.2020.04.011 -
Comparative toxicity of selected PAHs in rainbow trout hepatocytes: genotoxicity, oxidative stress and cytotoxicity
Drug Chem. Toxicol., 43 (1), 71-78
DOI 10.1080/01480545.2018.1497054 -
Response of human oral mucosal epithelial cells to different storage temperatures: A structural and transcriptional study
PLoS One, 15 (12), e0243914
DOI 10.1371/journal.pone.0243914 -
Noninvasive Electrical Stimulation Improves Photoreceptor Survival and Retinal Function in Mice with Inherited Photoreceptor Degeneration
Invest. Ophthalmol. Vis. Sci., 61 (4), 5
DOI 10.1167/iovs.61.4.5
Publications 2019
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Meibomian Gland Morphology Is a Sensitive Early Indicator of Meibomian Gland Dysfunction
Am. J. Ophthalmol., 200, 16-25
DOI 10.1016/j.ajo.2018.12.006 -
Proteomic and histopathological characterisation of sicca subjects and primary Sjogren's syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers
Arthritis Res. Ther., 21, 181
DOI 10.1186/s13075-019-1961-4 -
Resolvin D2 elevates cAMP to increase intracellular [Ca2+] and stimulate secretion from conjunctival goblet cells
Faseb J., 33 (7), 8468-8478
DOI 10.1096/fj.201802467R -
Elevated cytokine levels in tears and saliva of patients with primary Sjogren's syndrome correlate with clinical ocular and oral manifestations
Sci Rep, 9, 7319
DOI 10.1038/s41598-019-43714-5 -
Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
PLoS One, 14 (7), e0220079
DOI 10.1371/journal.pone.0220079 -
Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry
J. Bone Miner. Res., 34 (7), e3698-1296
DOI 10.1002/jbmr.3698 -
Resolvin D1, but not resolvin E1, transactivates the epidermal growth factor receptor to increase intracellular calcium and glycoconjugate secretion in rat and human conjunctival goblet cells
Exp. Eye Res., 180, 53-62
DOI 10.1016/j.exer.2018.11.018 -
Characteristics and Utility of Fundus Autofluorescence in Congenital Aniridia Using Scanning Laser Ophthalmoscopy
Invest. Ophthalmol. Vis. Sci., 60 (13), 4120-4128
DOI 10.1167/iovs.19-26994 -
Meibomian gland dysfunction and keratopathy are associated with dry eye disease in aniridia
Br. J. Ophthalmol., 103 (1), 119-124
DOI 10.1136/bjophthalmol-2017-310927 -
Transcriptomic analysis of MicroRNA expression in enamel-producing cells
Gene, 688, 193-203
DOI 10.1016/j.gene.2018.11.089 -
Dry eyes - diagnostics and treatment
Tidsskr. Nor. Laegeforen., 139 (11), 1061-1064 -
Interleukin-13 maintains the stemness of conjunctival epithelial cell cultures prepared from human limbal explants
PLoS One, 14 (2), e0211861
DOI 10.1371/journal.pone.0211861 -
Conjunctival Goblet Cells, the Overlooked Cells in Glaucoma Treatment
J. Glaucoma, 28 (4), 325-333
DOI 10.1097/IJG.0000000000001168 -
Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells
PLoS One, 14 (3), e0212524
DOI 10.1371/journal.pone.0212524 -
Evaluation of the Ocular Surface Disease Index Questionnaire as a Discriminative Test for Clinical Findings in Dry Eye Disease Patients
Curr. Eye Res., 44 (9), 941-947
DOI 10.1080/02713683.2019.1604972 -
Tear Metabolomics in Dry Eye Disease: A Review
Int. J. Mol. Sci., 20 (15), 3755
DOI 10.3390/ijms20153755 -
Hyaluronan-Based Hydrogel Scaffolds for Limbal Stem Cell Transplantation: A Review
Cells, 8 (3), 245
DOI 10.3390/cells8030245 -
A Hyaluronan Hydrogel Scaffold for Culture of Human Oral Mucosal Epithelial Cells in Limbal Stem-Cell Therapy
Bioengineering-Basel, 6 (4), 97
DOI 10.3390/bioengineering6040097 -
Mendelian Randomization Analysis Reveals a Causal Influence of Circulating Sclerostin Levels on Bone Mineral Density and Fractures
J. Bone Miner. Res., 34 (10), 1824-1836
DOI 10.1002/jbmr.3803 -
Transepithelial Topography-Guided Ablation Assisted by Epithelial Thickness Mapping for Treatment of Regression After Myopic Refractive Surgery
J. Refractive Surg., 35 (8), 525-+
DOI 10.3928/1081597X-20190730-01
Publications 2018
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Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density
Ann. Rheum. Dis., 77 (3), 378-385
DOI 10.1136/annrheumdis-2017-212469 -
Severity of clinical dry eye manifestations influences protein expression in tear fluid of patients with primary Sjogren's syndrome
PLoS One, 13 (10), e0205762
DOI 10.1371/journal.pone.0205762 -
Characterization and comparison of human limbal explant cultures grown under defined and xeno-free conditions
Exp. Eye Res., 176, 20-28
DOI 10.1016/j.exer.2018.06.019 -
Effect of anti-rheumatic treatment on selenium levels in inflammatory arthritis
J. Trace Elem. Med. Biol., 49, 91-97
DOI 10.1016/j.jtemb.2018.05.001 -
IGFBPL1 Regulates Axon Growth through IGF-1-mediated Signaling Cascades
Sci Rep, 8, 2054
DOI 10.1038/s41598-018-20463-5 -
Activation of the EGF Receptor by Histamine Receptor Subtypes Stimulates Mucin Secretion in Conjunctival Goblet Cells
Invest. Ophthalmol. Vis. Sci., 59 (8), 3543-3553
DOI 10.1167/iovs.18-2476 -
Cultured Human Retinal Pigment Epithelial (hRPE) Sheets: A Search for Suitable Storage Conditions
Microsc. microanal., 24 (2), 147-155
DOI 10.1017/S1431927618000144 -
Stage-related central corneal epithelial transformation in congenital aniridia-associated keratopathy
Ocul. Surf., 16 (1), 163-172
DOI 10.1016/j.jtos.2017.11.003 -
Wide-field corneal subbasal nerve plexus mosaics in age-controlled healthy and type 2 diabetes populations
Sci. Data, 5, 180075
DOI 10.1038/sdata.2018.75 -
Dendritic cell maturation in the corneal epithelium with onset of type 2 diabetes is associated with tumor necrosis factor receptor superfamily member 9
Sci Rep, 8, 14248
DOI 10.1038/s41598-018-32410-5 -
The Level of Inflammatory Tear Cytokines is Elevated in Congenital Aniridia and Associated with Meibomian Gland Dysfunction
Invest. Ophthalmol. Vis. Sci., 59 (5), 2197-2204
DOI 10.1167/iovs.18-24027 -
The genetics of congenital aniridia-a guide for the ophthalmologist
Surv. Ophthalmol., 63 (1), 105-113
DOI 10.1016/j.survophthal.2017.09.004 -
Coordinated collective migration and asymmetric cell division in confluent human keratinocytes without wounding
Nat. Commun., 9, 3665
DOI 10.1038/s41467-018-05578-7 -
Integrated analysis of DNA-methylation and gene expression using high-dimensional penalized regression: a cohort study on bone mineral density in postmenopausal women
BMC Med. Genomics, 11, 24
DOI 10.1186/s12920-018-0341-2 -
Signaling pathways activated by resolvin E1 to stimulate mucin secretion and increase intracellular Ca2+ in cultured rat conjunctival goblet cells
Exp. Eye Res., 173, 64-72
DOI 10.1016/j.exer.2018.04.015 -
Circadian clock and oral cancer (Review)
Mol. Clin. Oncol., 8 (2), 219-226
DOI 10.3892/mco.2017.1518 -
Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis
PLoS One, 13 (8), e0202346
DOI 10.1371/journal.pone.0202346 -
Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design
Sci Rep, 8, 5688
DOI 10.1038/s41598-018-24121-8 -
Color Vision in Aniridia
Invest. Ophthalmol. Vis. Sci., 59 (5), 2142-2152
DOI 10.1167/iovs.17-23047 -
High Throughput Screening of Additives Using Factorial Design to Promote Survival of Stored Cultured Epithelial Sheets
Stem Cells Int., 2018, 6545876
DOI 10.1155/2018/6545876 -
New animal model of extrinsic dental erosion-Erosive effect on the mouse molar teeth
Arch. Oral Biol., 96, 137-145
DOI 10.1016/j.archoralbio.2018.08.013 -
Effect of Transportation on Cultured Limbal Epithelial Sheets for Worldwide Treatment of Limbal Stem Cell Deficiency
Sci Rep, 8, 10502
DOI 10.1038/s41598-018-28553-0 -
Tear Production Levels and Dry Eye Disease Severity in a Large Norwegian Cohort
Curr. Eye Res., 43 (12), 1465-1470
DOI 10.1080/02713683.2018.1514055 -
Transcription and microRNA Profiling of Cultured Human Tympanic Membrane Epidermal Keratinocytes
JARO, 19 (3), 243-260
DOI 10.1007/s10162-018-0660-1
Publications 2017
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Identification of potential saliva and tear biomarkers in primary Sjogren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
Arthritis Res. Ther., 19, 14
DOI 10.1186/s13075-017-1228-x -
Medium-to Long-Term Results of Corneal Cross-Linking for Keratoconus Using Phototherapeutic Keratectomy for Epithelial Removal and Partial Stromal Ablation
J. Refractive Surg., 33 (7), 488-+
DOI 10.3928/1081597X-20170504-03 -
Meibomian gland features in a Norwegian cohort of patients with primary Sjogren 's syndrome
PLoS One, 12 (9), e0184284
DOI 10.1371/journal.pone.0184284 -
Anti-rheumatic treatment is not associated with reduction of pentraxin 3 in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
PLoS One, 12 (2), e0169830
DOI 10.1371/journal.pone.0169830 -
Methotrexate and anti-tumor necrosis factor treatment improves endothelial function in patients with inflammatory arthritis
Arthritis Res. Ther., 19, 232
DOI 10.1186/s13075-017-1439-1 -
Identification of Objective Morphometric Markers of Xerostomia in the Oral Mucosa Epithelium with In Vivo Confocal Microscopy
Microsc. microanal., 23 (1), 88-96
DOI 10.1017/S1431927617000022 -
Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells
Sci Rep, 7, 674
DOI 10.1038/s41598-017-00417-z -
Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets
Sci Rep, 7, 8206
DOI 10.1038/s41598-017-08586-7 -
Cultured epidermal stem cells in regenerative medicine
Stem Cell Res. Ther., 8, 155
DOI 10.1186/s13287-017-0587-1 -
Genetic Polymorphism of miR-196a-2 is Associated with Bone Mineral Density (BMD)
Int. J. Mol. Sci., 18 (12), 2529
DOI 10.3390/ijms18122529 -
Reduced Corneal Nerve Fiber Density in Type 2 Diabetes by Wide-Area Mosaic Analysis
Invest. Ophthalmol. Vis. Sci., 58 (14), 6318-6327
DOI 10.1167/iovs.17-22257 -
Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways
Invest. Ophthalmol. Vis. Sci., 58 (11), 4530-4544
DOI 10.1167/iovs.17-21914 -
Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus
Nat. Commun., 8, 121
DOI 10.1038/s41467-017-00108-3 -
Circadian rhythms and gene expression during mouse molar tooth development
Acta Odontol. Scand., 75 (2), 144-153
DOI 10.1080/00016357.2016.1271999 -
Plasma vitamin D levels and inflammation in the aortic wall of patients with coronary artery disease with and without inflammatory rheumatic disease
Scand. J. Rheumatol., 46 (3), 198-205
DOI 10.3109/03009742.2016.1172664 -
Impact of Storage Temperature on the Expression of Cell Survival Genes in Cultured ARPE-19 Cells
Curr. Eye Res., 42 (1), 134-144
DOI 10.3109/02713683.2016.1145236 -
Omics analysis of human bone to identify genes and molecular networks regulating skeletal remodeling in health and disease
Bone, 101, 88-95
DOI 10.1016/j.bone.2017.04.012 -
Distinct DNA methylation profiles in bone and blood of osteoporotic and healthy postmenopausal women
Epigenetics, 12 (8), 674-687
DOI 10.1080/15592294.2017.1345832 -
Regulatory roles of microRNAs in human dental tissues
Gene, 596, 9-18
DOI 10.1016/j.gene.2016.10.009 -
Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases
PLoS One, 12 (3), e0174577
DOI 10.1371/journal.pone.0174577 -
Interdisciplinary, Comprehensive Oral and Ocular Evaluation of Patients with Primary Sjogren's Syndrome
Sci Rep, 7, 10761
DOI 10.1038/s41598-017-10809-w
Publications 2016
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Xenobiotic- and Serum-Free Culture of Oral Mucosal Epithelial Cells on Contact Lenses
Curr. Eye Res., 41 (1), 20-27
DOI 10.3109/02713683.2015.1004720 -
Topography-Guided Transepithelial Surface Ablation in the Treatment of Moderate to High Astigmatism
J. Refractive Surg., 32 (6), 418-U78
DOI 10.3928/1081597X-20160428-01 -
Epithelial Thickness Profile Change After Combined Topography-Guided Transepithelial Photorefractive Keratectomy and Corneal Cross-linking in Treatment of Keratoconus
J. Refractive Surg., 32 (9), 626-634
DOI 10.3928/1081597X-20160531-02 -
The Silk-protein Sericin Induces Rapid Melanization of Cultured Primary Human Retinal Pigment Epithelial Cells by Activating the NF-kappa B Pathway
Sci Rep, 6, 22671
DOI 10.1038/srep22671 -
Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility
PLoS One, 11 (5), e0155214
DOI 10.1371/journal.pone.0155214 -
Evaluation of Equivalent Keratometry Readings Obtained by Pentacam HR (High Resolution)
PLoS One, 11 (3), e0150121
DOI 10.1371/journal.pone.0150121 -
Effect of Storage Temperature on the Phenotype of Cultured Epidermal Cells Stored in Xenobiotic-Free Medium
Curr. Eye Res., 41 (6), 757-768
DOI 10.3109/02713683.2015.1062113 -
Nucleus Morphometry in Cultured Epithelial Cells Correlates with Phenotype
Microsc. microanal., 22 (3), 612-620
DOI 10.1017/S1431927616000830 -
The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25
Scientifica, 2016, 1379643
DOI 10.1155/2016/1379643 -
Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease
Neurochem. Res., 41 (6), 1229-1236
DOI 10.1007/s11064-015-1792-x -
Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease (vol 41, pg 1237, 2016)
Neurochem. Res., 41 (6), 1237
DOI 10.1007/s11064-016-1916-y -
Identifying Novel Gene Variants in Coronary Artery Disease and Shared Genes With Several Cardiovascular Risk Factors
Circ.Res., 118 (1), 83-94
DOI 10.1161/CIRCRESAHA.115.306629 -
Novel Genetic Variants Associated With Increased Vertebral Volumetric BMD, Reduced Vertebral Fracture Risk, and Increased Expression of SLC1A3 and EPHB2
J. Bone Miner. Res., 31 (12), 2085-2097
DOI 10.1002/jbmr.2913 -
Corneal Nerve Regeneration After Collagen Cross-Linking Treatment of Keratoconus A 5-Year Longitudinal Study
JAMA Ophthalmol., 134 (1), 70-78
DOI 10.1001/jamaophthalmol.2015.4518 -
Electrical Stimulation as a Means for Improving Vision
Am. J. Pathol., 186 (11), 2783-2797
DOI 10.1016/j.ajpath.2016.07.017 -
Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1(-/-) mice, a model of dry eye
Exp. Eye Res., 153, 27-41
DOI 10.1016/j.exer.2016.09.011 -
Tilting the lasso by knowledge-based post-processing
BMC Bioinformatics, 17, 344
DOI 10.1186/s12859-016-1210-7 -
Effect of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan (TM), on Symptoms, Fatigue and Quality of Life in Patients with Ulcerative Colitis in a Randomized Single-Blinded Placebo Controlled Study
PLoS One, 11 (3), e0150191
DOI 10.1371/journal.pone.0150191 -
Effect of the Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan (TM), on Symptoms, Fatigue and Quality of Life in Patients with Crohn's Disease in a Randomized Single-Blinded Placebo Controlled Study
PLoS One, 11 (7), e0159288
DOI 10.1371/journal.pone.0159288 -
Cytokine Levels After Consumption of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSan (TM), in Patients with Crohn's Disease and Ulcerative Colitis in a Randomized Single-Blinded Placebo-Controlled Study
Scand. J. Immunol., 84 (6), 323-331
DOI 10.1111/sji.12476 -
Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes
PLoS One, 11 (3), e0152526
DOI 10.1371/journal.pone.0152526 -
Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
J. Func. Biomater., 7 (1), 4
DOI 10.3390/jfb7010004 -
Culture of Oral Mucosal Epithelial Cells for the Purpose of Treating Limbal Stem Cell Deficiency
J. Func. Biomater., 7 (1), 5
DOI 10.3390/jfb7010005 -
Assessment of refractive astigmatism and simulated therapeutic refractive surgery strategies in coma-like-aberrations-dominant corneal optics
Eye Vis., 3, 13
DOI 10.1186/s40662-016-0044-8
Publications 2015
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Corneal collagen cross-linking (CXL) in thin corneas
Eye Vis., 2, 15
DOI 10.1186/s40662-015-0025-3 -
Postoperative Changes in Corneal Epithelial and Stromal Thickness Profiles After Photorefractive Keratectomy in Treatment of Myopia
J. Refractive Surg., 31 (7), 446-453
DOI 10.3928/1081597X-20150623-02 -
Concise Review: Comparison of Culture Membranes Used for Tissue Engineered Conjunctival Epithelial Equivalents
J. Func. Biomater., 6 (4), 1064-1084
DOI 10.3390/jfb6041064 -
The Impact of Storage Temperature on the Morphology, Viability, Cell Number and Metabolism of Cultured Human Conjunctival Epithelium
Curr. Eye Res., 40 (1), 30-39
DOI 10.3109/02713683.2014.909497 -
Keratometric Index Obtained by Fourier-Domain Optical Coherence Tomography
PLoS One, 10 (4), e0122441
DOI 10.1371/journal.pone.0122441 -
Effect of Storage Temperature on Structure and Function of Cultured Human Oral Keratinocytes
PLoS One, 10 (6), e0128306
DOI 10.1371/journal.pone.0128306 -
Focused Tortuosity Definitions Based on Expert Clinical Assessment of Corneal Subbasal Nerves
Invest. Ophthalmol. Vis. Sci., 56 (9), 5102-5109
DOI 10.1167/iovs.15-17284 -
Substrates for Expansion of Corneal Endothelial Cells towards Bioengineering of Human Corneal Endothelium
J. Func. Biomater., 6 (3), 917-945
DOI 10.3390/jfb6030917 -
Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells
J. Ophthalmol., 2015, 263756
DOI 10.1155/2015/263756 -
The Influence of DNA Methylation on Bone Cells
Curr. Genomics, 16 (6), 384-392
DOI 10.2174/1389202916666150817202913 -
Methylation of Bone SOST, Its mRNA, and Serum Sclerostin Levels Correlate Strongly With Fracture Risk in Postmenopausal Women
J. Bone Miner. Res., 30 (2), 249-256
DOI 10.1002/jbmr.2342 -
Genetic Sharing with Cardiovascular Disease Risk Factors and Diabetes Reveals Novel Bone Mineral Density Loci
PLoS One, 10 (12), e0144531
DOI 10.1371/journal.pone.0144531 -
Autofluorescence imaging in the differential diagnosis of optic disc melanocytoma
Acta Ophthalmol., 93 (5), 476-480
DOI 10.1111/aos.12725 -
Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
J. Func. Biomater., 6 (3), 863-888
DOI 10.3390/jfb6030863 -
Serum-Free and Xenobiotic-Free Preservation of Cultured Human Limbal Epithelial Cells
PLoS One, 10 (3), e0118517
DOI 10.1371/journal.pone.0118517 -
Concise Review: Transplantation of Cultured Oral Mucosal Epithelial Cells for Treating Limbal Stem Cell DeficiencyCurrent Status and Future Perspectives
Stem Cells, 33 (6), 1685-1695
DOI 10.1002/stem.1999
Publications 2014
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Identifying Common Genetic Variants in Blood Pressure Due to Polygenic Pleiotropy With Associated Phenotypes
Hypertension, 63 (4), 819-826
DOI 10.1161/HYPERTENSIONAHA.113.02077 -
beta-blockade abolishes the augmented cardiac tPA release induced by transactivation of heterodimerised bradykinin receptor-2 and beta(2)-adrenergic receptor in vivo
Thromb. Haemost., 112 (5), 951-959
DOI 10.1160/TH14-01-0059 -
Reliability of Corneal Dynamic Scheimpflug Analyser Measurements in Virgin and Post-PRK Eyes
PLoS One, 9 (10), e109577
DOI 10.1371/journal.pone.0109577 -
Cataract development in Norwegian patients with congenital aniridia
Acta Ophthalmol., 92 (2), E165-E167
DOI 10.1111/aos.12225 -
Objective assessment of changes in nuclear morphology and cell distribution following induction of apoptosis
Diagn. Pathol., 9, 92
DOI 10.1186/1746-1596-9-92 -
Effect of Storage Temperature on Cultured Epidermal Cell Sheets Stored in Xenobiotic-Free Medium
PLoS One, 9 (8), e105808
DOI 10.1371/journal.pone.0105808 -
Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment
PLoS Genet., 10 (6), e1004423
DOI 10.1371/journal.pgen.1004423 -
Antioxidants Improve the Viability of Stored Adult Retinal Pigment Epithelial-19 Cultures
OPHTHALMOL. THER., 3 (1-2), 49-61
DOI 10.1007/s40123-014-0024-9 -
Enamel Matrix Derivative Promote Primary Human Pulp Cell Differentiation and Mineralization
Int. J. Mol. Sci., 15 (5), 7731-7749
DOI 10.3390/ijms15057731 -
Corneal Collagen Cross-Linking with and without Epithelial Removal: A Contralateral Study with 0.5% Hypotonic Riboflavin Solution
Biomed Res. Int., 2014, 619398
DOI 10.1155/2014/619398
Publications 2013
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miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium
Exp. Eye Res., 115, 189-198
DOI 10.1016/j.exer.2013.07.003 -
Serum levels of lipoprotein(a) and E-selectin are reduced in rheumatoid arthritis patients treated with methotrexate or methotrexate in combination with TNF-alpha-inhibitor
Clin. Exp. Rheumatol., 31 (3), 415-421 -
In Vivo Morphology of the Limbal Palisades of Vogt Correlates With Progressive Stem Cell Deficiency in Aniridia-Related Keratopathy
Invest. Ophthalmol. Vis. Sci., 54 (8), 5333-5342
DOI 10.1167/iovs.13-11780 -
Correlation of Cytokine Levels and Microglial Cell Infiltration during Retinal Degeneration in RCS Rats
PLoS One, 8 (12), e82061
DOI 10.1371/journal.pone.0082061 -
Standardized Baseline Human Corneal Subbasal Nerve Density for Clinical Investigations With Laser-Scanning in Vivo Confocal Microscopy
Invest. Ophthalmol. Vis. Sci., 54 (10), 7091-7102
DOI 10.1167/iovs.13-12999 -
Optimization of Storage Temperature for Cultured ARPE-19 Cells
J. Ophthalmol., 2013, 216359
DOI 10.1155/2013/216359 -
Identification of transcriptional macromolecular associations in human bone using browser based in silico analysis in a giant correlation matrix
Bone, 53 (1), 69-78
DOI 10.1016/j.bone.2012.11.015 -
One-Step Transepithelial Topography-Guided Ablation in the Treatment of Myopic Astigmatism
PLoS One, 8 (6), e66618
DOI 10.1371/journal.pone.0066618
Publications 2012
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The development of T cell-dominated inflammatory responses induced by sodium lauryl sulphate in mouse oral mucosa
Arch. Oral Biol., 57 (6), 796-804
DOI 10.1016/j.archoralbio.2011.11.005 -
Is the Blood Basophil Count Sufficiently Precise, Accurate, and Specific? Three Automated Hematology Instruments and Flow Cytometry Compared
Am. J. Clin. Pathol., 137 (1), 86-92
DOI 10.1309/AJCP19BFTHYTMORO -
Absolute Neutrophil Counts From Automated Hematology Instruments Are Accurate and Precise Even at Very Low Levels
Am. J. Clin. Pathol., 137 (6), 862-869
DOI 10.1309/AJCPOJN03GOXZRZY -
Different cardiac tissue plasminogen activator release patterns by local stimulation of the endothelium and sympathetic nerves in pigs
Blood Coagul. Fibrinolysis, 23 (8), 714-722
DOI 10.1097/MBC.0b013e328357d388 -
Effect of Biopsy Location and Size on Proliferative Capacity of Ex Vivo Expanded Conjunctival Tissue
Invest. Ophthalmol. Vis. Sci., 53 (6), 2897-2903
DOI 10.1167/iovs.11-8269 -
Effects of serum-free storage on morphology, phenotype, and viability of ex vivo cultured human conjunctival epithelium
Exp. Eye Res., 94 (1), 109-116
DOI 10.1016/j.exer.2011.11.015 -
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture
Nature Genet., 44 (5), 491-+
DOI 10.1038/ng.2249 -
Biopsy harvesting site and distance from the explant affect conjunctival epithelial phenotype ex vivo
Exp. Eye Res., 104, 15-25
DOI 10.1016/j.exer.2012.09.007 -
Endothelial function improves within 6 weeks of treatment with methotrexate or methotrexate in combination with a TNF-alpha inhibitor in rheumatoid arthritis patients
Scand. J. Rheumatol., 41 (3), 240-242
DOI 10.3109/03009742.2012.656698 -
Relations of Serum COMP to Cardiovascular Risk Factors and Endothelial Function in Patients with Rheumatoid Arthritis Treated with Methotrexate and TNF-alpha Inhibitors
J. Rheumatol., 39 (7), 1341-1347
DOI 10.3899/jrheum.111401 -
Intramedullary nailing of femoral shaft fractures in polytraumatized patients. A longitudinal, prospective and observational study of the procedure-related impact on cardiopulmonary- and inflammatory responses
Scand. J. Trauma Resusc. Emerg. Med., 20, 2
DOI 10.1186/1757-7241-20-2 -
Effect of AndoSan (TM) on expression of adhesion molecules and production of reactive oxygen species in human monocytes and granulocytes in vivo
Scand. J. Gastroenterol., 47 (8-9), 984-992
DOI 10.3109/00365521.2012.660544 -
Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus
PLoS Genet., 8 (7), e1002718
DOI 10.1371/journal.pgen.1002718 -
Safety and Efficacy of Epithelium-On Corneal Collagen Cross-Linking Using a Multifactorial Approach to Achieve Proper Stromal Riboflavin Saturation
J. Ophthalmol., 2012, 498435
DOI 10.1155/2012/498435 -
Recovery, survival, and function of transfused platelets and detection of platelet engraftment after allogeneic stem cell transplantation
Transfusion, 52 (6), 1321-1332
DOI 10.1111/j.1537-2995.2011.03442.x
Publications 2011
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The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation
Adv. Pharmacol. Sci., 2011, 157015
DOI 10.1155/2011/157015 -
Molecular Disease Map of Bone Characterizing the Postmenopausal Osteoporosis Phenotype
J. Bone Miner. Res., 26 (8), 1793-1801
DOI 10.1002/jbmr.396
Publications 2010
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Periostin is a collagen associated bone matrix protein regulated by parathyroid hormone
Matrix Biol., 29 (7), 594-601
DOI 10.1016/j.matbio.2010.07.001 -
Eight genes are highly associated with BMD variation in postmenopausal Caucasian women
Bone, 46 (3), 604-612
DOI 10.1016/j.bone.2009.11.007 -
Skeletal Site-Related Variation in Human Trabecular Bone Transcriptome and Signaling
PLoS One, 5 (5), e10692
DOI 10.1371/journal.pone.0010692
Publications 2007
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Osteopenia, decreased bone formation and impaired osteoblast development in Sox4 heterozygous mice
J. Cell Sci., 120 (16), 2785-2795
DOI 10.1242/jcs.003855 -
Levetiracetam, phenytoin, and valproate act differently on rat bone mass, structure and metabolism
Epilepsia, 48 (10), 1850-1860
DOI 10.1111/j.1528-1167.2007.01176.x -
Abnormal muscle and hematopoietic gene expression may be important for clinical morbidity in primary hyperparathyroidism
Am. J. Physiol.-Endocrinol. Metab., 292 (5), E1465-E1473
DOI 10.1152/ajpendo.00487.2006
Publications 2006
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Gene expression profiles give insight into the molecular pathology of bone in primary hyperparathyroidism
Bone, 39 (1), 189-198
DOI 10.1016/j.bone.2005.12.020 -
The effect of enamel matrix derivative on gene expression in osteoblasts
Eur. J. Oral Sci., 114 1, 205-211
DOI 10.1111/j.1600-0722.2006.00333.x
Publications 2005
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Thyrotrophin-releasing hormone receptor 1 and prothyrotrophin-releasing hormone mRNA expression in the central nervous system are regulated by suckling in lactating rats
Eur. J. Endocrinol., 152 (5), 791-803
DOI 10.1530/eje.1.01902
Publications 2004
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Butyrate response factor 1 is regulated by parathyroid hormone and bone morphogenetic protein-2 in osteoblastic cells
Biochem. Biophys. Res. Commun., 324 (1), 218-223
DOI 10.1016/j.bbrc.2004.09.030
Publications 2003
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Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning
Anticancer Res., 23 (3B), 2201-2216
Publications 2000
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Sox-4 messenger RNA is expressed in the embryonic growth plate and regulated via the parathyroid hormone/parathyroid hormone-related protein receptor in osteoblast-like cells
J. Bone Miner. Res., 15 (12), 2402-2412
DOI 10.1359/jbmr.2000.15.12.2402