❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Cancer Genetics ❭ Translational studies on solid tumours [Helland] ❭ Clinical trials ❭ NIPU

Malignant mesothelioma treated with immune checkpoint inhibitors 
with or without cancer vaccine (the NIPU-study)

– a phase II randomised clinical and translational trial

  • EudraCT number: 2019-002721-30 
  • Clinicaltrials.gov: NCT04300244
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Home Dept. of Cancer Genetics Translational studies on solid tumours [Helland]

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Recent publications

Nymoen HM, Zhao Z, Horndalsveen H, Bjaanæs MM, Grønberg BH, Halvorsen T, Madebo T, Aanerud M, Koivunen J, Oselin K, Cicenas S, Helbekkmo N, Ahvonen J, Silvoniemi M, Alver TN, Dalen T, Öjlert ÅK, Farooqi SJ, Helland Å, Haakensen VD (2026)
Gut microbiota alterations in patients with non-small-cell lung cancer undergoing chemoradiotherapy
Mol Oncol (in press)
DOI 10.1002/1878-0261.70326, PubMed 42703809

Hoshino A, Costa-Silva B, Shen TL, Rodrigues G, Hashimoto A, Mark MT, Molina H, Kohsaka S, Di Giannatale A, Ceder S, Singh S, Williams C, Soplop N, Uryu K, Pharmer L, King T, Bojmar L, Davies AE, Ararso Y, Zhang T, Zhang H, Hernandez J, Weiss JM, Dumont-Cole VD, Kramer K, Wexler LH, Narendran A, Schwartz GK, Healey JH, Sandstrom P et al. (2026)
Editorial Expression of Concern: Tumour exosome integrins determine organotropic metastasis
Nature, 656 (8128), E44
DOI 10.1038/s41586-026-10977-8, PubMed 42557336

Horndalsveen H, Haakensen VD, Madebo T, Grønberg BH, Halvorsen TO, Bjaanæs MM, Danielsen BK, Børve M, Kokkvoll S, Boda TSD, Öjlert ÅK, Helland Å (2026)
ctDNA-Based MRD Detection in Stage III NSCLC Treated With Chemoradiotherapy and Durvalumab
J Thorac Oncol, 103992 (in press)
DOI 10.1016/j.jtho.2026.103992, PubMed 42336205

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