❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Cancer Genetics ❭ Translational studies on solid tumours [Helland] ❭ Clinical trials ❭ IMPRESS-Norway ❭

IMPRESS-Norway

– A multi-cohort phase 2 treatment clinical study investigating efficacy of approved drugs outside indication in patients with advanced cancer

  • EudraCT number: 2023-507894-16-00
  • Clinicaltrials.gov: NCT04817956
About the study
Study design
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Home Dept. of Cancer Genetics Translational studies on solid tumours [Helland]

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Recent publications

Van der Pol H, Kringelbach T, Martin Agudo M, Bratseth Stav G, Fagereng GL, Fiocco M, Sørum Falk R, Homer V, Haj Mohammad S, Timmer H, Verlingue L, Helland Å, Rohrberg K, Lassen U, Halford S, Jalkanen K, Juslin T, Krebs MG, Oliveira J, Baltruskeviciene E, Ojamaa K, Taskén K, Gelderblom H (2026)
Procedures of data merging in precision cancer medicine: the PRIME-ROSE project
Acta Oncol, 65, 1-8
DOI 10.2340/1651-226X.2026.44889, PubMed 41496458

Nassar AH, Bou Farhat E, Abushukair H, Alchoueriy M, Salem S, Machaalani M, Adib E, Henske EP, Babu P, Choueiri TK, Rakaee M, Busund LR, Takabe Y, Lau SF, Rall K, Naqash AR, Jansen C, Wang X, Challa P, Tarantino P, Partridge AH, Tolaney SM, Kwiatkowski DJ, Winer EP (2025)
Molecular and clinical insights of trastuzumab deruxtecan efficacy in advanced breast cancer
J Natl Cancer Inst (in press)
DOI 10.1093/jnci/djaf344, PubMed 41418409

Romero-Becerra R, Zhao Z, Nebdal D, Müller E, Bergholtz H, Norum JH, Aittokallio T (2025)
Improved analysis of in vivo drug combination experiments with a comprehensive statistical framework and web-tool
Nat Commun, 16 (1), 10151
DOI 10.1038/s41467-025-65218-9, PubMed 41258298

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