❭ Research by medical division ❭ Cancer Medicine ❭ Institute for Cancer Research ❭ Dept. of Cancer Genetics ❭ Translational studies on solid tumours [Helland] ❭ Clinical trials ❭ COM-IT-2 ❭

COM-IT-2 Immunotherapy combined with extensive radiotherapy for the treatment of stage IV non-small cell lung cancer

– a phase II randomised clinical and translational trial

  • EudraCT number: 2021-003266
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Home Dept. of Cancer Genetics Translational studies on solid tumours [Helland]

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Recent publications

Ayuda-Durán P, Hanes R, Rønneberg L, Alver TN, Øy GF, Hauge S, Andersen AN, Egeland EV, Juell S, Nakken S, Asenso TQ, Zucknick M, Syljuåsen RG, Mælandsmo GM, Hovig E, Enserink JM (2026)
Systematic interrogation of drug sensitivities in melanoma reveals potent synergistic and antagonistic drug combinations with translational potential
Commun Med (Lond) (in press)
DOI 10.1038/s43856-026-01583-w, PubMed 42062484

Chen C, Cheng J, Hou R, Zheng X, Su L, Bjaanæs MM, Karlsson A, Planck M, Staaf J, Helland Å, Esteller M, Christiani DC, Chen F, Cao X, Zhang R (2026)
DNA methylation and expression of MAPRE3 affect overall survival of early-stage non-small cell lung cancer patients
Mol Oncol (in press)
DOI 10.1002/1878-0261.70260, PubMed 42033322

Jamaly S, Rakaee M, Ichinose K, Maeda K, Otomo K, Koga T, Tsokos MG, Tsokos GC (2026)
Cell-Targeted Inhibition of CaMK4 Suppresses Tertiary Lymphoid-like Structure Development in Lupus-Prone Mice
Int J Mol Sci, 27 (7)
DOI 10.3390/ijms27073190, PubMed 41977373

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