Helene Knævelsrud

  • Visiting scientist
  • +47 22 78 19 65

Helene Knævelsrud Associate Professor - Division of Biochemistry



Cell Stress and Cancer






From the news:

Helene Knævelsrud receives ERC starting grant

Helene Knævelsrud new member of The Young Academy of Norway


Publications 2023

Johannessen JA, Formica M, Haukeland ALC, Bråthen NR, Al Outa A, Aarsund M, Therrien M, Enserink JM, Knævelsrud H (2023)
The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae
iScience, 26 (10), 107726
DOI 10.1016/j.isci.2023.107726, PubMed 37720104

Publications 2021

Formica M, Storaci AM, Bertolini I, Carminati F, Knævelsrud H, Vaira V, Vaccari T (2021)
V-ATPase controls tumor growth and autophagy in a Drosophila model of gliomagenesis
Autophagy, 17 (12), 4442-4452
DOI 10.1080/15548627.2021.1918915, PubMed 33978540

Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM et al. (2021)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
Autophagy, 17 (1), 1-382
DOI 10.1080/15548627.2020.1797280, PubMed 33634751

Publications 2017

Søreng K, Knævelsrud H, Holland P, Simonsen A (2017)
HS1BP3 inhibits autophagy by regulation of PLD1
Autophagy, 13 (5), 985-986
DOI 10.1080/15548627.2017.1291483, PubMed 28318354

Publications 2016

Baril C, Gavory G, Bidla G, Knævelsrud H, Sauvageau G, Therrien M (2016)
Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila
Dev Biol, 421 (1), 16-26
DOI 10.1016/j.ydbio.2016.11.003, PubMed 27838340

Holland P, Knævelsrud H, Søreng K, Mathai BJ, Lystad AH, Pankiv S, Bjørndal GT, Schultz SW, Lobert VH, Chan RB, Zhou B, Liestøl K, Carlsson SR, Melia TJ, Di Paolo G, Simonsen A (2016)
HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
Nat Commun, 7, 13889
DOI 10.1038/ncomms13889, PubMed 28004827

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM et al. (2016)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy, 12 (1), 1-222
DOI 10.1080/15548627.2015.1100356, PubMed 26799652

Publications 2015

Trusch F, Matena A, Vuk M, Koerver L, Knævelsrud H, Freemont PS, Meyer H, Bayer P (2015)
The N-terminal Region of the Ubiquitin Regulatory X (UBX) Domain-containing Protein 1 (UBXD1) Modulates Interdomain Communication within the Valosin-containing Protein p97
J Biol Chem, 290 (49), 29414-27
DOI 10.1074/jbc.M115.680686, PubMed 26475856

Publications 2014

Baril C, Lefrançois M, Sahmi M, Knævelsrud H, Therrien M (2014)
Apical accumulation of the Sevenless receptor tyrosine kinase during Drosophila eye development is promoted by the small GTPase Rap1
Genetics, 197 (4), 1237-50
DOI 10.1534/genetics.114.166272, PubMed 24899161

Publications 2013

Knævelsrud H, Carlsson SR, Simonsen A (2013)
SNX18 tubulates recycling endosomes for autophagosome biogenesis
Autophagy, 9 (10), 1639-41
DOI 10.4161/auto.26124, PubMed 24113029

Knævelsrud H, Søreng K, Raiborg C, Håberg K, Rasmuson F, Brech A, Liestøl K, Rusten TE, Stenmark H, Neufeld TP, Carlsson SR, Simonsen A (2013)
Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation
J Cell Biol, 202 (2), 331-49
DOI 10.1083/jcb.201205129, PubMed 23878278

Publications 2012

Knævelsrud H, Simonsen A (2012)
Lipids in autophagy: constituents, signaling molecules and cargo with relevance to disease
Biochim Biophys Acta, 1821 (8), 1133-45
DOI 10.1016/j.bbalip.2012.01.001, PubMed 22269166

Publications 2010

Knaevelsrud H, Simonsen A (2010)
Fighting disease by selective autophagy of aggregate-prone proteins
FEBS Lett, 584 (12), 2635-45
DOI 10.1016/j.febslet.2010.04.041, PubMed 20412801

Knævelsrud H, Ahlquist T, Merok MA, Nesbakken A, Stenmark H, Lothe RA, Simonsen A (2010)
UVRAG mutations associated with microsatellite unstable colon cancer do not affect autophagy
Autophagy, 6 (7), 863-70
DOI 10.4161/auto.6.7.13033, PubMed 20724836

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