Section for Cellular Therapy

Publications published since 1984 from OUS - Section for Cellular Therapy

222 publications found

Publications 2018

  1. Oei VYS, Siernicka M, Graczyk-Jarzynka A, Hoel HJ, Yang W, Palacios D, Almåsbak H, Bajor M, Clement D, Brandt L, Önfelt B, Goodridge J, Winiarska M, Zagozdzon R, Olweus J, Kyte JA, Malmberg KJ (2018)
    Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors
    Cancer Immunol Res, 6 (4), 467-480
    PubMed 29459477
  2. Våtsveen TK, Myhre MR, Steen CB, Wälchli S, Lingjærde OC, Bai B, Dillard P, Theodossiou TA, Holien T, Sundan A, Inderberg EM, Smeland EB, Myklebust JH, Oksvold MP (2018)
    Artesunate shows potent anti-tumor activity in B-cell lymphoma
    J Hematol Oncol, 11 (1), 23
    PubMed 29458389

Publications 2017

  1. Bollum LK, Huse K, Oksvold MP, Bai B, Hilden VI, Forfang L, Yoon SO, Wälchli S, Smeland EB, Myklebust JH (2017)
    BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5
    PLoS One, 12 (5), e0177188
    PubMed 28489883
  2. Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2017)
    The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
    Pathol Oncol Res (in press)
    PubMed 29098521
  3. Giustacchini A, Thongjuea S, Barkas N, Woll PS, Povinelli BJ, Booth CAG, Sopp P, Norfo R, Rodriguez-Meira A, Ashley N, Jamieson L, Vyas P, Anderson K, Segerstolpe Å, Qian H, Olsson-Strömberg U, Mustjoki S, Sandberg R, Jacobsen SEW, Mead AJ (2017)
    Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
    Nat Med, 23 (6), 692-702
    PubMed 28504724
  4. Inderberg EM, Mensali N, Oksvold MP, Fallang LE, Fåne A, Skorstad G, Stenvik GE, Progida C, Bakke O, Kvalheim G, Myklebust JH, Wälchli S (2017)
    Human c-SRC kinase (CSK) overexpression makes T cells dummy
    Cancer Immunol Immunother, 67 (4), 525-536
    PubMed 29248956
  5. Inderberg EM, Wälchli S, Myhre MR, Trachsel S, Almåsbak H, Kvalheim G, Gaudernack G (2017)
    T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces <i>in vivo</i> tumor growth
    Oncoimmunology, 6 (4), e1302631
    PubMed 28507809
  6. Josefsson SE, Huse K, Kolstad A, Beiske K, Pende D, Steen CB, Inderberg EM, Lingjærde OC, Østenstad B, Smeland EB, Levy R, Irish JM, Myklebust JH (2017)
    T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling
    Clin Cancer Res, 24 (4), 870-881
    PubMed 29217528
  7. Koksal H, Walchli S (2017)
    Fishing therapeutic T-cell receptors in healthy donor blood, is safety predictable?
    Transl. Cancer Res., 6 3, S622-S624
  8. Li X, Grigalavicius M, Li Y, Li X, Zhong Y, Huang R, Yu D, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
    MtDNA depletion influences the transition of CD44 subtypes in human prostate cancer DU145 cells
    Tumour Biol, 39 (8), 1010428317713671
    PubMed 28789597
  9. Li X, Lu J, Kan Q, Li X, Fan Q, Li Y, Huang R, Slipicevic A, Dong HP, Eide L, Wang J, Zhang H, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
    Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
    Sci Rep, 7 (1), 5081
    PubMed 28698547
  10. Lilleby W, Gaudernack G, Brunsvig PF, Vlatkovic L, Schulz M, Mills K, Hole KH, Inderberg EM (2017)
    Phase I/IIa clinical trial of a novel hTERT peptide vaccine in men with metastatic hormone-naive prostate cancer
    Cancer Immunol Immunother, 66 (7), 891-901
    PubMed 28391357
  11. Morris JL, Fane A, Sarovich DS, Price EP, Rush CM, Govan BL, Parker E, Mayo M, Currie BJ, Ketheesan N (2017)
    Increased Neurotropic Threat from Burkholderia pseudomallei Strains with a B. mallei-like Variation in the bimA Motility Gene, Australia
    Emerg Infect Dis, 23 (5)
    PubMed 28418830
  12. Nestvold J, Wang MY, Camilio KA, Zinöcker S, Tjelle TE, Lindberg A, Haug BE, Kvalheim G, Sveinbjørnsson B, Rekdal Ø (2017)
    Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model
    Oncoimmunology, 6 (8), e1338236
    PubMed 28920000
  13. Ohnstad HO, Borgen E, Falk RS, Lien TG, Aaserud M, Sveli MAT, Kyte JA, Kristensen VN, Geitvik GA, Schlichting E, Wist EA, Sørlie T, Russnes HG, Naume B (2017)
    Prognostic value of PAM50 and risk of recurrence score in patients with early-stage breast cancer with long-term follow-up
    Breast Cancer Res, 19 (1), 120
    PubMed 29137653
  14. Schive SW, Mirlashari MR, Hasvold G, Wang M, Josefsen D, Gullestad HP, Korsgren O, Foss A, Kvalheim G, Scholz H (2017)
    Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
    Cell Med, 9 (3), 103-116
    PubMed 28713640
  15. Walseng E, Köksal H, Sektioglu IM, Fåne A, Skorstad G, Kvalheim G, Gaudernack G, Inderberg EM, Wälchli S (2017)
    A TCR-based Chimeric Antigen Receptor
    Sci Rep, 7 (1), 10713
    PubMed 28878363

Publications 2016

  1. Belnoue E, Di Berardino-Besson W, Gaertner H, Carboni S, Dunand-Sauthier I, Cerini F, Suso-Inderberg EM, Wälchli S, König S, Salazar AM, Hartley O, Dietrich PY, Walker PR, Derouazi M (2016)
    Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants
    Mol Ther, 24 (9), 1675-85
    PubMed 27377043
  2. Cairns L, Aspeslagh S, Anichini A, Kyte JA, Blank C, Ascierto P, Rekers N, Straten PT, Awada A (2016)
    Cancer immunotherapy: from the lab to clinical applications-Potential impact on cancer centres' organisation
    Ecancermedicalscience, 10, 691
    PubMed 27994647
  3. Carretero R, Sektioglu IM, Garbi N, Salgado OC, Beckhove P, Hämmerling GJ (2016)
    Corrigendum: Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8(+) T cells
    Nat Immunol, 17 (2), 214
    PubMed 26784268
  4. Eide HA, Halvorsen AR, Sandhu V, Fåne A, Berg J, Haakensen VD, Kure EH, Brustugun OT, Kiserud CE, Kyte JA, Helland Å (2016)
    Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
    Clin Transl Immunology, 5 (11), e109
    PubMed 27990285
  5. Elvsåshagen T, Zuzarte P, Westlye LT, Bøen E, Josefsen D, Boye B, Hol PK, Malt UF, Young LT, Andreazza AC (2016)
    Dentate gyrus-cornu ammonis (CA) 4 volume is decreased and associated with depressive episodes and lipid peroxidation in bipolar II disorder: Longitudinal and cross-sectional analyses
    Bipolar Disord, 18 (8), 657-668
    PubMed 27995733
  6. Kyte JA, Gaudernack G, Faane A, Lislerud K, Inderberg EM, Brunsvig P, Aamdal S, Kvalheim G, Wälchli S, Pule M (2016)
    T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
    Oncoimmunology, 5 (12), e1249090
    PubMed 28123886
  7. Kyte JA, Aamdal S, Dueland S, Sæbøe-Larsen S, Inderberg EM, Madsbu UE, Skovlund E, Gaudernack G, Kvalheim G (2016)
    Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
    Oncoimmunology, 5 (11), e1232237
    PubMed 27999747
  8. Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen RG, Peng Q, Wang J, Zhang H, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2016)
    MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
    Oncotarget, 7 (26), 40297-40313
    PubMed 27248169
  9. Mensali N, Ying F, Sheng VO, Yang W, Walseng E, Kumari S, Fallang LE, Kolstad A, Uckert W, Malmberg KJ, Wälchli S, Olweus J (2016)
    Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA
    Oncoimmunology, 5 (5), e1138199
    PubMed 27467957
  10. Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, Wälchli S, Green MR, Trøen G, Liestøl K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R (2016)
    Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling
    Blood, 129 (6), 759-770
    PubMed 28011673
  11. Schive SW, Foss A, Sahraoui A, Kloster-Jensen K, Hafsahl G, Kvalheim G, Lundgren T, von Zur-Mühlen B, Felldin M, Rafael E, Lempinen M, Korsgren O, Jenssen TG, Mishra V, Scholz H (2016)
    Cost and clinical outcome of islet transplantation in Norway 2010-2015
    Clin Transplant, 31 (1)
    PubMed 27862341
  12. Sioud M, Nyakas M, Sæbøe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G (2016)
    Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
    Case Rep Med, 2016, 9639585
    PubMed 27504122

Publications 2015

  1. Almåsbak H, Walseng E, Kristian A, Myhre MR, Suso EM, Munthe LA, Andersen JT, Wang MY, Kvalheim G, Gaudernack G, Kyte JA (2015)
    Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model
    Gene Ther, 22 (5), 391-403
    PubMed 25652098
  2. Eide N, Faye RS, Høifødt HK, Sandstad B, Qvale G, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2015)
    Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox
    Acta Ophthalmol, 93 (1), 59-66
    PubMed 25613126
  3. Hansen GL, Gaudernack G, Brunsvig PF, Cvancarova M, Kyte JA (2015)
    Immunological factors influencing clinical outcome in lung cancer patients after telomerase peptide vaccination
    Cancer Immunol Immunother, 64 (12), 1609-21
    PubMed 26498005
  4. Naderi EH, Skah S, Ugland H, Myklebost O, Sandnes DL, Torgersen ML, Josefsen D, Ruud E, Naderi S, Blomhoff HK (2015)
    Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death
    Mol Cancer, 14, 14
    PubMed 25623255
  5. Ozguven BY, Tuncel D, Polat N, Sakiz D, Kabukcuoglu F, Koksal H, Kaya H (2015)
    Solid-pseudopapillary neoplasm of the pancreas: Clinicopathologic and immunohistochemical analysis of nine cases
    Indian J Pathol Microbiol, 58 (3), 292-5
    PubMed 26275248
  6. Sioud M, Mobergslien A, Sæbøe-Larssen S (2015)
    Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses
    Methods Mol Biol, 1218, 269-76
    PubMed 25319657
  7. Tadesse FG, Mensali N, Fallang LE, Walseng E, Yang W, Olweus J, Wälchli S (2015)
    Unpredicted phenotypes of two mutants of the TcR DMF5
    J Immunol Methods, 425, 37-44
    PubMed 26079729
  8. Theodossiou TA, Wälchli S, Olsen CE, Skarpen E, Berg K (2015)
    Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
    ACS Chem Biol, 11 (1), 251-62
    PubMed 26569462
  9. Yu D, Zhong Y, Li X, Li Y, Li X, Cao J, Fan H, Yuan Y, Ji Z, Qiao B, Wen JG, Zhang M, Kvalheim G, Nesland JM, Suo Z (2015)
    ILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro
    Oncotarget, 6 (40), 42687-703
    PubMed 26528857

Publications 2014

  1. Husøy MA, Brinch L, Tjønnfjord GE, Gedde-Dahl T, Heldal D, Holme PA, Dybedal I, Kolstad A, Akkök ÇA, Rollag H, Gaustad P, Bergan S, Egeland T, Josefsen D, Kvalheim G, Fløisand Y (2014)
    [Allogeneic stem-cell transplantation in adults 1985-2012: results and development]
    Tidsskr Nor Laegeforen, 134 (16), 1569-75
    PubMed 25178233
  2. Skårn M, Noordhuis P, Wang MY, Veuger M, Kresse SH, Egeland EV, Micci F, Namløs HM, Håkelien AM, Olafsrud SM, Lorenz S, Haraldsen G, Kvalheim G, Meza-Zepeda LA, Myklebost O (2014)
    Generation and characterization of an immortalized human mesenchymal stromal cell line
    Stem Cells Dev, 23 (19), 2377-89
    PubMed 24857590
  3. Subklewe M, Geiger C, Lichtenegger FS, Javorovic M, Kvalheim G, Schendel DJ, Bigalke I (2014)
    New generation dendritic cell vaccine for immunotherapy of acute myeloid leukemia
    Cancer Immunol Immunother, 63 (10), 1093-103
    PubMed 25186611
  4. Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P et al. (2014)
    Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
    Cancer Cell, 25 (6), 794-808
    PubMed 24835589

Publications 2013

  1. del Campo AB, Kyte JA, Carretero J, Zinchencko S, Méndez R, González-Aseguinolaza G, Ruiz-Cabello F, Aamdal S, Gaudernack G, Garrido F, Aptsiauri N (2013)
    Immune escape of cancer cells with beta2-microglobulin loss over the course of metastatic melanoma
    Int J Cancer, 134 (1), 102-13
    PubMed 23784959
  2. Kaur K, Mirlashari MR, Kvalheim G, Kjeldsen-Kragh J (2013)
    3',4'-Dimethoxyflavone and valproic acid promotes the proliferation of human hematopoietic stem cells
    Stem Cell Res Ther, 4 (3), 60
    PubMed 23706670
  3. Kyte JA (2013)
    [The cancer riddle is outdated]
    Tidsskr Nor Laegeforen, 133 (18), 1907
    PubMed 24084948
  4. Liu Y, Wu X, Li X, Kvalheim G, Axcrona U, Axcrona K, Suo Z (2013)
    Blocking mtDNA replication upregulates the expression of stemness-related genes in prostate cancer cell lines
    Ultrastruct Pathol, 37 (4), 258-66
    PubMed 23634795
  5. Ma Y, Liang D, Liu J, Wen JG, Servoll E, Waaler G, Sæter T, Axcrona K, Vlatkovic L, Axcrona U, Paus E, Yang Y, Zhang Z, Kvalheim G, Nesland JM, Suo Z (2013)
    SHBG is an important factor in stemness induction of cells by DHT in vitro and associated with poor clinical features of prostate carcinomas
    PLoS One, 8 (7), e70558
    PubMed 23936228
  6. Mustjoki S, Richter J, Barbany G, Ehrencrona H, Fioretos T, Gedde-Dahl T, Gjertsen BT, Hovland R, Hernesniemi S, Josefsen D, Koskenvesa P, Dybedal I, Markevärn B, Olofsson T, Olsson-Strömberg U, Rapakko K, Thunberg S, Stenke L, Simonsson B, Porkka K, Hjorth-Hansen H, Nordic CML Study Group (NCMLSG) (2013)
    Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients
    Leukemia, 27 (7), 1520-6
    PubMed 23328954
  7. Naderi EH, Ugland HK, Diep PP, Josefsen D, Ruud E, Naderi S, Blomhoff HK (2013)
    Selective inhibition of cell death in malignant vs normal B-cell precursors: implications for cAMP in development and treatment of BCP-ALL
    Blood, 121 (10), 1805-13
    PubMed 23299313
  8. Pi F, Dillard P, Limozin L, Charrier A, Sengupta K (2013)
    Nanometric protein-patch arrays on glass and polydimethylsiloxane for cell adhesion studies
    Nano Lett, 13 (7), 3372-8
    PubMed 23808889
  9. Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
    Clinical significance of disseminated tumour cells in non-small cell lung cancer
    Br J Cancer, 109 (5), 1264-70
    PubMed 23942067
  10. Sioud M, Saebøe-Larssen S, Hetland TE, Kaern J, Mobergslien A, Kvalheim G (2013)
    Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients
    Int J Oncol, 43 (1), 280-8
    PubMed 23620105
  11. Sioud M, Skorstad G, Mobergslien A, Sæbøe-Larssen S (2013)
    A novel peptide carrier for efficient targeting of antigens and nucleic acids to dendritic cells
    FASEB J, 27 (8), 3272-83
    PubMed 23671272
  12. Vik-Mo EO, Nyakas M, Mikkelsen BV, Moe MC, Due-Tønnesen P, Suso EM, Sæbøe-Larssen S, Sandberg C, Brinchmann JE, Helseth E, Rasmussen AM, Lote K, Aamdal S, Gaudernack G, Kvalheim G, Langmoen IA (2013)
    Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
    Cancer Immunol Immunother, 62 (9), 1499-509
    PubMed 23817721
  13. Wang P, Gao Q, Suo Z, Munthe E, Solberg S, Ma L, Wang M, Westerdaal NA, Kvalheim G, Gaudernack G (2013)
    Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines
    PLoS One, 8 (3), e57020
    PubMed 23469181
  14. Wang P, Suo Z, Wang M, Høifødt HK, Fodstad O, Gaudernack G, Kvalheim G (2013)
    In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines
    Exp Hematol Oncol, 2 (1), 16
    PubMed 23738757

Publications 2012

  1. Fløisand Y, Brinch L, Gedde-Dahl T, Tjønnfjord GE, Dybedal I, Holte H, Heldal D, Torfoss D, Aurlien E, Lauritzsen GF, Fosså A, Lehne G, Baggerød E, Kvalheim G, Egeland T, Bishop MR, Fowler DH, Kolstad A (2012)
    Ultra-short course sirolimus contributes to effective GVHD prophylaxis after reduced-intensity allogeneic hematopoietic cell transplantation
    Bone Marrow Transplant, 47 (12), 1552-7
    PubMed 22522568
  2. Huse K, Bakkebø M, Wälchli S, Oksvold MP, Hilden VI, Forfang L, Bredahl ML, Liestøl K, Alizadeh AA, Smeland EB, Myklebust JH (2012)
    Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma
    PLoS One, 7 (10), e46117
    PubMed 23049692
  3. Johnson E, Førland DT, Hetland G, Sætre L, Olstad OK, Lyberg T (2012)
    Effect of AndoSan™ on expression of adhesion molecules and production of reactive oxygen species in human monocytes and granulocytes in vivo
    Scand J Gastroenterol, 47 (8-9), 984-92
    PubMed 22564240
  4. Langmoen IA, Foss A, Kvalheim G, Engebretsen L, Glover JC (2012)
    [Stem cell research--new hope?]
    Tidsskr Nor Laegeforen, 132 (23-24), 2584
    PubMed 23338066
  5. Ma Y, Liang D, Liu J, Axcrona K, Kvalheim G, Giercksky KE, Nesland JM, Suo Z (2012)
    Synergistic effect of SCF and G-CSF on stem-like properties in prostate cancer cell lines
    Tumour Biol, 33 (4), 967-78
    PubMed 22252524
  6. Mathiesen RR, Borgen E, Renolen A, Løkkevik E, Nesland JM, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Kvalheim G, Lønning PE, Naume B (2012)
    Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
    Breast Cancer Res, 14 (4), R117
    PubMed 22889108

Publications 2011

  1. Eide MB, Lauritzsen GF, Kvalheim G, Kolstad A, Fagerli UM, Maisenhölder M, Østenstad B, Fluge Ø, Delabie J, Aarset H, Liestøl K, Holte H (2011)
    High dose chemotherapy with autologous stem cell support for patients with histologically transformed B-cell non-Hodgkin lymphomas. A Norwegian multi centre phase II study
    Br J Haematol, 152 (5), 600-10
    PubMed 21241276
  2. Elvsåshagen T, Vera E, Bøen E, Bratlie J, Andreassen OA, Josefsen D, Malt UF, Blasco MA, Boye B (2011)
    The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
    J Affect Disord, 135 (1-3), 43-50
    PubMed 21880373
  3. Førland DT, Johnson E, Saetre L, Lyberg T, Lygren I, Hetland G (2011)
    Effect of an extract based on the medicinal mushroom Agaricus blazei Murill on expression of cytokines and calprotectin in patients with ulcerative colitis and Crohn's disease
    Scand J Immunol, 73 (1), 66-75
    PubMed 21129005
  4. Hetland G, Johnson E, Lyberg T, Kvalheim G (2011)
    The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation
    Adv Pharmacol Sci, 2011, 157015
    PubMed 21912538
  5. Huijbers IJ, Soudja SM, Uyttenhove C, Buferne M, Inderberg-Suso EM, Colau D, Pilotte L, Powis de Tenbossche CG, Chomez P, Brasseur F, Schmitt-Verhulst AM, Van den Eynde BJ (2011)
    Minimal tolerance to a tumor antigen encoded by a cancer-germline gene
    J Immunol, 188 (1), 111-21
    PubMed 22140254
  6. Josefsen D, Forfang L, Dyrhaug M, Blystad AK, Stokke T, Smeland EB, Kvalheim G (2011)
    Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy
    Eur J Haematol, 87 (6), 494-502
    PubMed 21752097
  7. Kyte JA, Gaudernack G, Dueland S, Trachsel S, Julsrud L, Aamdal S (2011)
    Telomerase peptide vaccination combined with temozolomide: a clinical trial in stage IV melanoma patients
    Clin Cancer Res, 17 (13), 4568-80
    PubMed 21586625
  8. Ma Y, Liang D, Liu J, Axcrona K, Kvalheim G, Stokke T, Nesland JM, Suo Z (2011)
    Prostate cancer cell lines under hypoxia exhibit greater stem-like properties
    PLoS One, 6 (12), e29170
    PubMed 22216200
  9. Mohty M, Duarte RF, Croockewit S, Hübel K, Kvalheim G, Russell N (2011)
    The role of plerixafor in optimizing peripheral blood stem cell mobilization for autologous stem cell transplantation
    Leukemia, 25 (1), 1-6
    PubMed 21224858
  10. Suso EM, Dueland S, Rasmussen AM, Vetrhus T, Aamdal S, Kvalheim G, Gaudernack G (2011)
    hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
    Cancer Immunol Immunother, 60 (6), 809-18
    PubMed 21365467
  11. Torfoss D, Sandstad B, Mollnes TE, Høiby EA, Holte H, Bjerner J, Bjøro T, Gaudernack G, Kvalheim G, Kvaløy S (2011)
    The mild inflammatory response in febrile neutropenic lymphoma patients with low risk of complications is more pronounced in patients receiving tobramycin once daily compared with three times daily
    Scand J Immunol, 74 (6), 632-9
    PubMed 21883353
  12. Zinöcker S, Wang MY, Gaustad P, Kvalheim G, Rolstad B, Vaage JT (2011)
    Mycoplasma contamination revisited: mesenchymal stromal cells harboring Mycoplasma hyorhinis potently inhibit lymphocyte proliferation in vitro
    PLoS One, 6 (1), e16005
    PubMed 21264307

Publications 2010

  1. Almåsbak H, Lundby M, Rasmussen AM (2010)
    Non-MHC-dependent redirected T cells against tumor cells
    Methods Mol Biol, 629, 453-93
    PubMed 20387166
  2. Almåsbak H, Rian E, Hoel HJ, Pulè M, Wälchli S, Kvalheim G, Gaudernack G, Rasmussen AM (2010)
    Transiently redirected T cells for adoptive transfer
    Cytotherapy, 13 (5), 629-40
    PubMed 21174490
  3. Jantunen E, Kvalheim G (2010)
    Mobilization strategies in hard-to-mobilize patients with lymphoid malignancies
    Eur J Haematol, 85 (6), 463-71
    PubMed 20738393
  4. Johnsen HE, Geisler C, Juvonen E, Remes K, Juliusson G, Hörnsten P, Kvaloy S, Kvalheim G, Jürgensen GW, Pedersen LM, Bergmann OJ, Schmitz A, Boegsted M (2010)
    Priming with r-metHuSCF and filgrastim or chemotherapy and filgrastim in patients with malignant lymphomas: a randomized phase II pilot study of mobilization and engraftment
    Bone Marrow Transplant, 46 (1), 44-51
    PubMed 20436517
  5. Kyte JA (2010)
    Third International Conference on Cancer Vaccines/Adjuvants/Delivery for the Next Decade (CVADD 2009)
    Expert Rev Vaccines, 9 (2), 119-23
    PubMed 20109021
  6. Kyte JA (2010)
    [We know more than we can understand]
    Tidsskr Nor Laegeforen, 130 (22), 2217
    PubMed 21109831
  7. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Stromberg M, Wiedswang G, Kvalheim G, Karesen R, Nesland JM, Borresen-Dale AL, Sorlie T (2010)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
    Mol. Oncol., 4 (2), 169
  8. Rasmussen AM, Borelli G, Hoel HJ, Lislerud K, Gaudernack G, Kvalheim G, Aarvak T (2010)
    Ex vivo expansion protocol for human tumor specific T cells for adoptive T cell therapy
    J Immunol Methods, 355 (1-2), 52-60
    PubMed 20171968
  9. Tamburstuen MV, Reppe S, Spahr A, Sabetrasekh R, Kvalheim G, Slaby I, Syversen U, Lyngstadaas SP, Reseland JE (2010)
    Ameloblastin promotes bone growth by enhancing proliferation of progenitor cells and by stimulating immunoregulators
    Eur J Oral Sci, 118 (5), 451-9
    PubMed 20831578
  10. Tamburstuen MV, Reseland JE, Spahr A, Brookes SJ, Kvalheim G, Slaby I, Snead ML, Lyngstadaas SP (2010)
    Ameloblastin expression and putative autoregulation in mesenchymal cells suggest a role in early bone formation and repair
    Bone, 48 (2), 406-13
    PubMed 20854943

Publications 2009

  1. Eide N, Faye RS, Høifødt HK, Øvergaard R, Jebsen P, Kvalheim G, Fodstad Ø (2009)
    Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients
    Acta Ophthalmol, 87 (8), 830-6
    PubMed 19055657
  2. Gao Q, Geng L, Kvalheim G, Gaudernack G, Suo Z (2009)
    Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3
    Ultrastruct Pathol, 33 (4), 175-81
    PubMed 19728235
  3. Huang TS, Grodeland G, Sleire L, Wang MY, Kvalheim G, Laerum OD (2009)
    Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro
    Chronobiol Int, 26 (2), 242-57
    PubMed 19212839
  4. Kyte JA (2009)
    [Nobel Prize for mitotic clock]
    Tidsskr Nor Laegeforen, 129 (23), 2470
    PubMed 19997132

Publications 2008

  1. Ikdahl T, Josefsen D, Jakobsen E, Delabie J, Fosså SD (2008)
    Concurrent mediastinal germ-cell tumour and haematological malignancy: case report and short review of literature
    Acta Oncol, 47 (3), 466-9
    PubMed 18348004
  2. Johannessen M, Myhre MR, Dragset M, Tümmler C, Moens U (2008)
    Phosphorylation of human polyomavirus BK agnoprotein at Ser-11 is mediated by PKC and has an important regulative function
    Virology, 379 (1), 97-109
    PubMed 18635245
  3. Lazarova P, Kvalheim G, Gercheva L, Metodiev K (2008)
    Experimental attempt to produce mRNA transfected dendritic cells derived from enriched CD34+blood progenitor cells
    Cent. Eur. J. Med., 3 (1), 21-28

Publications 2007

  1. Berg A, Berner A, Lilleby W, Bruland ØS, Fosså SD, Nesland JM, Kvalheim G (2007)
    Impact of disseminated tumor cells in bone marrow at diagnosis in patients with nonmetastatic prostate cancer treated by definitive radiotherapy
    Int J Cancer, 120 (8), 1603-9
    PubMed 17230512
  2. Jarnjak-Jankovic S, Hammerstad H, Saebøe-Larssen S, Kvalheim G, Gaudernack G (2007)
    A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines
    BMC Cancer, 7, 119
    PubMed 17608923
  3. Jarnjak-Jankovic S, Saebøe-Larssen S, Kvalheim G, Gaudernack G (2007)
    mRNA transfection of DC in the immature or mature state: comparable in vitro priming of Th and cytotoxic T lymphocytes against DC electroporated with tumor cell line-derived mRNA
    Cytotherapy, 9 (6), 587-92
    PubMed 17882723
  4. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Strømberg M, Wiedswang G, Kvalheim G, Kåresen R, Nesland JM, Børresen-Dale AL, Sørlie T (2007)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
    Mol Oncol, 1 (2), 160-71
    PubMed 19383292
  5. Shanker A, Verdeil G, Buferne M, Inderberg-Suso EM, Puthier D, Joly F, Nguyen C, Leserman L, Auphan-Anezin N, Schmitt-Verhulst AM (2007)
    CD8 T cell help for innate antitumor immunity
    J Immunol, 179 (10), 6651-62
    PubMed 17982055
  6. Textoris-Taube K, Henklein P, Pollmann S, Bergann T, Weisshoff H, Seifert U, Drung I, Mügge C, Sijts A, Kloetzel PM, Kuckelkorn U (2007)
    The N-terminal flanking region of the TRP2360-368 melanoma antigen determines proteasome activator PA28 requirement for epitope liberation
    J Biol Chem, 282 (17), 12749-54
    PubMed 17308306

Publications 2006

  1. Brunsvig PF, Aamdal S, Gjertsen MK, Kvalheim G, Markowski-Grimsrud CJ, Sve I, Dyrhaug M, Trachsel S, Møller M, Eriksen JA, Gaudernack G (2006)
    Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
    Cancer Immunol Immunother, 55 (12), 1553-64
    PubMed 16491401
  2. Davidson B, Konstantinovsky S, Kleinberg L, Nguyen MT, Bassarova A, Kvalheim G, Nesland JM, Reich R (2006)
    The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma
    Gynecol Oncol, 102 (3), 453-61
    PubMed 16494928
  3. Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G (2006)
    Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
    Int J Cancer, 118 (11), 2877-81
    PubMed 16381016
  4. Gratama J, Kvalheim G, Orfao A (2006)
    Standardization of cell analysis methods in clinical cellular therapy programs: A challenge for ISCT
    Cytotherapy, 8 (6), 528-9
    PubMed 17148028
  5. Huijbers IJ, Krimpenfort P, Chomez P, van der Valk MA, Song JY, Inderberg-Suso EM, Schmitt-Verhulst AM, Berns A, Van den Eynde BJ (2006)
    An inducible mouse model of melanoma expressing a defined tumor antigen
    Cancer Res, 66 (6), 3278-86
    PubMed 16540681
  6. Kyte JA (2006)
    [Cancer vaccines]
    Tidsskr Nor Laegeforen, 126 (22), 2969-73
    PubMed 17117197
  7. Kyte JA, Gaudernack G (2006)
    Immuno-gene therapy of cancer with tumour-mRNA transfected dendritic cells
    Cancer Immunol Immunother, 55 (11), 1432-42
    PubMed 16612595
  8. Kyte JA, Kvalheim G, Lislerud K, thor Straten P, Dueland S, Aamdal S, Gaudernack G (2006)
    T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
    Cancer Immunol Immunother, 56 (5), 659-75
    PubMed 16947019
  9. Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M, Gullestad HP, Ryder T, Lislerud K, Hammerstad H, Gaudernack G (2006)
    Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
    Cancer Gene Ther, 13 (10), 905-18
    PubMed 16710345
  10. Lazarova P, Wu Q, Kvalheim G, Suo Z, Haakenstad KW, Metodiev K, Nesland JM (2006)
    Growth factor receptors in hematopoietic stem cells: EPH family expression in CD34+ and CD133+ cell populations from mobilized peripheral blood
    Int J Immunopathol Pharmacol, 19 (1), 49-56
    PubMed 16569339
  11. Saebøe-Larssen S, Fossberg E, Gaudernack G (2006)
    Characterization of novel alternative splicing sites in human telomerase reverse transcriptase (hTERT): analysis of expression and mutual correlation in mRNA isoforms from normal and tumour tissues
    BMC Mol Biol, 7, 26
    PubMed 16939641
  12. Wiedswang G, Borgen E, Schirmer C, Kåresen R, Kvalheim G, Nesland JM, Naume B (2006)
    Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer
    Int J Cancer, 118 (8), 2013-9
    PubMed 16287086

Publications 2005

  1. Elloul S, Elstrand MB, Nesland JM, Tropé CG, Kvalheim G, Goldberg I, Reich R, Davidson B (2005)
    Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
    Cancer, 103 (8), 1631-43
    PubMed 15742334
  2. Jarnjak-Jankovic S, Pettersen RD, Saebøe-Larssen S, Wesenberg F, Gaudernack G (2005)
    Evaluation of dendritic cells loaded with apoptotic cancer cells or expressing tumour mRNA as potential cancer vaccines against leukemia
    BMC Cancer, 5, 20
    PubMed 15720715
  3. Jarnjak-Jankovic S, Pettersen RD, Saebøe-Larssen S, Wesenberg F, Olafsen MR, Gaudernack G (2005)
    Preclinical evaluation of autologous dendritic cells transfected with mRNA or loaded with apoptotic cells for immunotherapy of high-risk neuroblastoma
    Cancer Gene Ther, 12 (8), 699-707
    PubMed 15846368
  4. Josefsen D, Fosså S (2005)
    The management strategies for stage I seminoma
    Clin Oncol (R Coll Radiol), 17 (7), 539-42
    PubMed 16238141
  5. Konstantinovsky S, Nielsen S, Vyberg M, Kvalheim G, Nesland JM, Reich R, Davidson B (2005)
    Angiogenic molecule expression is downregulated in effusions from breast cancer patients
    Breast Cancer Res Treat, 94 (1), 71-80
    PubMed 16142438
  6. Kvalheim G (2005)
    Stem cell therapy still not here
    Cytotherapy, 7 (5), 456-7
    PubMed 16236635
  7. Kyte JA, Kvalheim G, Aamdal S, Saebøe-Larssen S, Gaudernack G (2005)
    Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
    Cancer Gene Ther, 12 (6), 579-91
    PubMed 15818380
  8. Mu LJ, Kyte JA, Kvalheim G, Aamdal S, Dueland S, Hauser M, Hammerstad H, Waehre H, Raabe N, Gaudernack G (2005)
    Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
    Br J Cancer, 93 (7), 749-56
    PubMed 16136047

Publications 2004

  1. Abrahamsen JF, Rusten L, Bakken AM, Bruserud Ø (2004)
    Better preservation of early hematopoietic progenitor cells when human peripheral blood progenitor cells are cryopreserved with 5 percent dimethylsulfoxide instead of 10 percent dimethylsulfoxide
    Transfusion, 44 (5), 785-9
    PubMed 15104663
  2. Blystad AK, Delabie J, Kvaløy S, Holte H, Vålerhaugen H, Ikonomou I, Kvalheim G (2004)
    Infused CD34 cell dose, but not tumour cell content of peripheral blood progenitor cell grafts, predicts clinical outcome in patients with diffuse large B-cell lymphoma and follicular lymphoma grade 3 treated with high-dose therapy
    Br J Haematol, 125 (5), 605-12
    PubMed 15147376
  3. Lazarova P, Lijun M, Hammerstad H, Nesland J, Gaudernack G, Kvalheim G (2004)
    Experimental attempt to introduce a vaccine therapy by using DC-developed from CD34+cells
    NATO SCI SER I LIFE, 361, 134
  4. Mu LJ, Lazarova P, Gaudernack G, Saeboe-Larssen S, Kvalheim G (2004)
    Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34(+) blood progenitor cells
    Int J Immunopathol Pharmacol, 17 (3), 255-63
    PubMed 15461859
  5. Naume B, Wiedswang G, Borgen E, Kvalheim G, Kåresen R, Qvist H, Janbu J, Harbitz T, Nesland JM (2004)
    The prognostic value of isolated tumor cells in bone marrow in breast cancer patients: evaluation of morphological categories and the number of clinically significant cells
    Clin Cancer Res, 10 (9), 3091-7
    PubMed 15131048
  6. Smeland S, Blystad AK, Kvaløy SO, Ikonomou IM, Delabie J, Kvalheim G, Hammerstrøm J, Lauritzsen GF, Holte H (2004)
    Treatment of Burkitt's/Burkitt-like lymphoma in adolescents and adults: a 20-year experience from the Norwegian Radium Hospital with the use of three successive regimens
    Ann Oncol, 15 (7), 1072-8
    PubMed 15205201
  7. Wiedswang G, Borgen E, Kåresen R, Qvist H, Janbu J, Kvalheim G, Nesland JM, Naume B (2004)
    Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavorable clinical outcome
    Clin Cancer Res, 10 (16), 5342-8
    PubMed 15328170
  8. Yildirim S, Köksal H, Celayir F, Erdem L, Oner M, Baykan A (2004)
    Colonic interposition vs. gastric pull-up after total esophagectomy
    J Gastrointest Surg, 8 (6), 675-8
    PubMed 15358327
  9. Østby I, Kvalheim G, Rusten LS, Grøttum P (2004)
    Mathematical modeling of granulocyte reconstitution after high-dose chemotherapy with stem cell support: effect of post-transplant G-CSF treatment
    J Theor Biol, 231 (1), 69-83
    PubMed 15363930

Publications 2003

  1. Kvalheim G, Gratwohl A, Urbano-Ispizua A, JACIE national representatives (2003)
    JACIE accreditation in Europe moves ahead
    Cytotherapy, 5 (4), 306-8
    PubMed 12944236
  2. Lilleby W, Nesland JM, Fosså SD, Torlakovic G, Waehre H, Kvalheim G (2003)
    The prognostic impact of cytokeratin-positive cells in bone marrow of patients with localized prostate cancer
    Int J Cancer, 103 (1), 91-6
    PubMed 12455058
  3. Mu LJ, Gaudernack G, Saebøe-Larssen S, Hammerstad H, Tierens A, Kvalheim G (2003)
    A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines
    Scand J Immunol, 58 (5), 578-86
    PubMed 14629630
  4. Noble A, Leggat JA, Inderberg EM (2003)
    CD8+ immunoregulatory cells in the graft-versus-host reaction: CD8 T cells activate dendritic cells to secrete interleukin-12/interleukin-18 and induce T helper 1 autoantibody
    Immunology, 109 (4), 476-86
    PubMed 12871213
  5. Ogreid P, Kvalheim G (2003)
    Old and new research into micrometastases in prostate cancer
    Scand J Urol Nephrol Suppl (212), 37-9
    PubMed 12841326
  6. Ogreid P, Kvalheim G (2003)
    Old and new research into micrometastases in prostate cancer
    Scand. J. Urol. Nephrol., 37 212, 37-39
  7. Paus E, Almåsbak H, Børmer OP, Warren DJ (2003)
    A single-chain-Fv-based immunofluorometric assay specific for the CEA variant NCA-2
    J Immunol Methods, 283 (1-2), 125-39
    PubMed 14659905
  8. Rinaldo CH, Myhre MR, Alstad H, Nilssen Ø, Traavik T (2003)
    Human polyomavirus BK (BKV) transiently transforms and persistently infects cultured osteosarcoma cells
    Virus Res, 93 (2), 181-7
    PubMed 12782366
  9. Schouten HC, Qian W, Kvaloy S, Porcellini A, Hagberg H, Johnsen HE, Doorduijn JK, Sydes MR, Kvalheim G (2003)
    High-dose therapy improves progression-free survival and survival in relapsed follicular non-Hodgkin's lymphoma: results from the randomized European CUP trial
    J Clin Oncol, 21 (21), 3918-27
    PubMed 14517188
  10. Taraldsrud E, Kvalheim G, Jørstad S, Stavem K, Aandahl GS (2003)
    A survey of therapeutic hemapheresis in Norway year 2000
    Transfus Apher Sci, 28 (2), 135-41
    PubMed 12679117
  11. Taraldsrud E, Aandahl GS, Stavem K, Kvalheim G, Jørstad S (2003)
    [Therapeutic hemapheresis]
    Tidsskr Nor Laegeforen, 123 (17), 2439-42
    PubMed 14594145
  12. Wiedswang G, Borgen E, Kåresen R, Kvalheim G, Nesland JM, Qvist H, Schlichting E, Sauer T, Janbu J, Harbitz T, Naume B (2003)
    Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer
    J Clin Oncol, 21 (18), 3469-78
    PubMed 12972522
  13. Østby I, Rusten LS, Kvalheim G, Grøttum P (2003)
    A mathematical model for reconstitution of granulopoiesis after high dose chemotherapy with autologous stem cell transplantation
    J Math Biol, 47 (2), 101-36
    PubMed 12883857

Publications 2002

  1. Gjertsen MK, Saeterdal I, Saebøe-Larssen S, Gaudernack G (2002)
    HLA-A3 restricted mutant ras specific cytotoxic T-lymphocytes induced by vaccination with T-helper epitopes
    J Mol Med (Berl), 81 (1), 43-50
    PubMed 12545248
  2. Lundqvist A, Noffz G, Pavlenko M, Saebøe-Larssen S, Fong T, Maitland N, Pisa P (2002)
    Nonviral and viral gene transfer into different subsets of human dendritic cells yield comparable efficiency of transfection
    J Immunother, 25 (6), 445-54
    PubMed 12439342
  3. Saebøe-Larssen S, Fossberg E, Gaudernack G (2002)
    mRNA-based electrotransfection of human dendritic cells and induction of cytotoxic T lymphocyte responses against the telomerase catalytic subunit (hTERT)
    J Immunol Methods, 259 (1-2), 191-203
    PubMed 11730854
  4. Yildirim S, Tok H, Köksal H, Erdem L, Baykan A (2002)
    Allopurinol plus pentoxifilline in hepatic ischaemia/reperfusion injury
    Asian J Surg, 25 (2), 149-53
    PubMed 12376236

Publications 2001

  1. Aurlien E, Holte H, Kvaloy S, Jakobsen E, Rusten LS, Kvalheim G (2001)
    Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
    Eur. J. Haematol., 66 64, 14-20
  2. Aurlien E, Holte H, Kvaløy S, Jakobsen E, Rusten LS, Kvalheim G (2001)
    Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
    Eur J Haematol Suppl, 64, 14-20
    PubMed 11486395
  3. Blystad AK, Enblad G, Kvaløy S, Berglund A, Delabie J, Holte H, Carlson K, Kvalheim G, Bengtsson M, Hagberg H (2001)
    High-dose therapy with autologous stem cell transplantation in patients with peripheral T cell lymphomas
    Bone Marrow Transplant, 27 (7), 711-6
    PubMed 11360110
  4. Blystad AK, Holte H, Kvaløy S, Smeland E, Delabie J, Kvalheim G (2001)
    High-dose therapy in patients with Hodgkin's disease: the use of selected CD34(+) cells is as safe as unmanipulated peripheral blood progenitor cells
    Bone Marrow Transplant, 28 (9), 849-57
    PubMed 11781645
  5. Blystad AK, Torlakovic E, Holte H, Kvaløy S, Lenschow E, Kvalheim G (2001)
    CD34(+) cell enrichment depletes atypical CD30(+) cells from PBPC grafts in patients with HD
    Cytotherapy, 3 (4), 295-305
    PubMed 12171718
  6. Hall KS, Wiklund T, Erikstein B, Holte H, Kvalheim G, Sommer HH, Andersen A, Skovlund E, Bergh J, Hall C (2001)
    Effects of dose-intensive chemotherapy and radiotherapy on serum n-terminal proatrial natriuretic peptide in high-risk breast cancer patients
    Breast Cancer Res Treat, 67 (3), 235-44
    PubMed 11561769
  7. Kvalheim G, Urbano-Ispizua A, Gratwohl A (2001)
    Regulatory aspects and accreditation of the clinical use of hematopoietic progenitor cells in Europe
    J Biol Regul Homeost Agents, 15 (1), 79-80
    PubMed 11388748
  8. Naume B, Borgen E, Kvalheim G, Kåresen R, Qvist H, Sauer T, Kumar T, Nesland JM (2001)
    Detection of isolated tumor cells in bone marrow in early-stage breast carcinoma patients: comparison with preoperative clinical parameters and primary tumor characteristics
    Clin Cancer Res, 7 (12), 4122-9
    PubMed 11751511
  9. Saeterdal I, Bjørheim J, Lislerud K, Gjertsen MK, Bukholm IK, Olsen OC, Nesland JM, Eriksen JA, Møller M, Lindblom A, Gaudernack G (2001)
    Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer
    Proc Natl Acad Sci U S A, 98 (23), 13255-60
    PubMed 11687624

Publications 2000

  1. Aurlien E, Larsen RH, Kvalheim G, Bruland OS (2000)
    Demonstration of highly specific toxicity of the alpha-emitting radioimmunoconjugate(211)At-rituximab against non-Hodgkin's lymphoma cells
    Br J Cancer, 83 (10), 1375-9
    PubMed 11044364
  2. Josefsen D, Myklebust JH, Lømo J, Sioud M, Blomhoff HK, Smeland EB (2000)
    Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells
    Stem Cells, 18 (4), 261-72
    PubMed 10924092
  3. Myklebust JH, Smeland EB, Josefsen D, Sioud M (2000)
    Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
    Blood, 95 (2), 510-8
    PubMed 10627456
  4. Simonsen GS, Myhre MR, Dahl KH, Olsvik O, Sundsfjord A (2000)
    Typeability of Tn1546-like elements in vancomycin-resistant enterococci using long-range PCRs and specific analysis of polymorphic regions
    Microb Drug Resist, 6 (1), 49-57
    PubMed 10868807

Publications 1999

  1. Blystad A, Kvalheim G, Torlakovic E, Holte H, Jacobsen E, Beiske K, Vâlerhaugen H, Lenschow E, Kvaloy S (1999)
    High-dose therapy supported with immunomagnetic purged autologous bone marrow in high-grade B cell non-Hodgkin's lymphoma
    Bone Marrow Transplant, 24 (8), 865-72
    PubMed 10516698
  2. Borgen E, Naume B, Nesland JM, Kvalheim G, Beiske K, Fodstad O, Diel I, Solomayer EF, Theocharous P, Coombes RC, Smith BM, Wunder E, Marolleau JP, Garcia J, Pantel K (1999)
    Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells
    Cytotherapy, 1 (5), 377-88
    PubMed 20426539
  3. Crown J, Coiffier B, Cortés-Funes H, Guillaume T, Kanz L, Kvalheim G, Marty M, Symann M (1999)
    ESTIC position paper: high-dose chemotherapy for breast cancer, investigation should continue
    Ann Oncol, 10 (8), 903-5
    PubMed 10509150
  4. Davidson B, Risberg B, Kristensen G, Kvalheim G, Emilsen E, Bjåmer A, Berner A (1999)
    Detection of cancer cells in effusions from patients diagnosed with gynaecological malignancies. Evaluation of five epithelial markers
    Virchows Arch, 435 (1), 43-9
    PubMed 10431845
  5. Josefsen D, Blomhoff HK, Lømo J, Blystad AK, Smeland EB (1999)
    Retinoic acid induces apoptosis of human CD34+ hematopoietic progenitor cells: involvement of retinoic acid receptors and retinoid X receptors depends on lineage commitment of the hematopoietic progenitor cells
    Exp Hematol, 27 (4), 642-53
    PubMed 10210322
  6. Josefsen D, Myklebust JH, Lynch DH, Stokke T, Blomhoff HK, Smeland EB (1999)
    Fas ligand promotes cell survival of immature human bone marrow CD34+CD38- hematopoietic progenitor cells by suppressing apoptosis
    Exp Hematol, 27 (9), 1451-9
    PubMed 10480436
  7. Kvalheim G, Berli M (1999)
    EBMT and ISHAGE-Europe create a foundation for inspection and accreditation in Europe
    Cytotherapy, 1 (5), 363-4
    PubMed 20426536
  8. Kvalheim G, Naume B, Nesland JM (1999)
    Minimal residual disease in breast cancer
    Cancer Metastasis Rev, 18 (1), 101-8
    PubMed 10505549
  9. Lindman H, Wiklund T, Holte H, Ljungman P, Blomqvist C, Kvalheim G, Bengtsson M, Höglund M, Wilking N, Bergh J (1999)
    FEC mobilized stem cells for high-dose therapy in breast cancer patients. SB6 9401 Study Group
    Acta Oncol, 38 (2), 239-45
    PubMed 10227447
  10. Munthe LA, Kyte JA, Bogen B (1999)
    Resting small B cells present endogenous immunoglobulin variable-region determinants to idiotope-specific CD4(+) T cells in vivo
    Eur J Immunol, 29 (12), 4043-52
    PubMed 10602015
  11. Myklebust JH, Josefsen D, Blomhoff HK, Levy FO, Naderi S, Reed JC, Smeland EB (1999)
    Activation of the cAMP signaling pathway increases apoptosis in human B-precursor cells and is associated with downregulation of Mcl-1 expression
    J Cell Physiol, 180 (1), 71-80
    PubMed 10362019
  12. Nordøy T, Kolstad A, Endresen P, Holte H, Kvaløy S, Kvalheim G, Husebekk A (1999)
    Persistent changes in the immune system 4-10 years after ABMT
    Bone Marrow Transplant, 24 (8), 873-8
    PubMed 10516699
  13. Serke S, Johnsen H, Huhn D, Kvalheim G (1999)
    European survey of the flow cytometric determination of CD34-expressing cells
    Cytotherapy, 1 (4), 343-7
    PubMed 20426564

Publications 1998

  1. Aurlien E, Holte H, Pharo A, Kvaløy S, Jakobsen E, Smeland EB, Kvalheim G (1998)
    Combination chemotherapy with mitoguazon, ifosfamide, MTX, etoposide (MIME) and G-CSF can efficiently mobilize PBPC in patients with Hodgkin's and non-Hodgkin's lymphoma
    Bone Marrow Transplant, 21 (9), 873-8
    PubMed 9613778
  2. Borgen E, Beiske K, Trachsel S, Nesland JM, Kvalheim G, Herstad TK, Schlichting E, Qvist H, Naume B (1998)
    Immunocytochemical detection of isolated epithelial cells in bone marrow: non-specific staining and contribution by plasma cells directly reactive to alkaline phosphatase
    J Pathol, 185 (4), 427-34
    PubMed 9828843
  3. Kvalheim G (1998)
    Detection and quantification of residual disease in bone marrow and PBPC
    EUROCANCER 98, 19-21
  4. Kvalheim G (1998)
    Diagnosis of minimal residual disease in bone marrow and blood in cancer patients--methods and clinical implications
    Acta Oncol, 37 (5), 455-62
    PubMed 9831374
  5. Naume B, Borgen E, Nesland JM, Beiske K, Gilen E, Renolen A, Ravnås G, Qvist H, Kåresen R, Kvalheim G (1998)
    Increased sensitivity for detection of micrometastases in bone-marrow/peripheral-blood stem-cell products from breast-cancer patients by negative immunomagnetic separation
    Int J Cancer, 78 (5), 556-60
    PubMed 9808522
  6. Oftung F, Borka E, Kvalheim G, Mustafa AS (1998)
    Mycobacterial crossreactivity of M. tuberculosis reactive T cell clones from naturally converted PPD positive healthy subjects
    FEMS Immunol Med Microbiol, 20 (3), 231-8
    PubMed 9566494

Publications 1997

  1. Naume B, Borgen E, Beiske K, Herstad TK, Ravnås G, Renolen A, Trachsel S, Thrane-Steen K, Funderud S, Kvalheim G (1997)
    Immunomagnetic techniques for the enrichment and detection of isolated breast carcinoma cells in bone marrow and peripheral blood
    J Hematother, 6 (2), 103-14
    PubMed 9131439

Publications 1996

  1. Atta J, Martin H, Bruecher J, Elsner S, Wassmann B, Rode C, Russ A, Kvalheim G, Hoelzer D (1996)
    Residual leukemia and immunomagnetic bead purging in patients with BCR-ABL-positive acute lymphoblastic leukemia
    Bone Marrow Transplant, 18 (3), 541-8
    PubMed 8879615
  2. Kolstad A, Holte H, Kvaløy S, Jakobsen E, Erikstein B, Aurlien E, Kvalheim G, Bøhler PJ, Langholm R (1996)
    [High-dose therapy with autologous stem cell support in malignant lymphoma and breast cancer. Experiences with hematopoietic stem cells isolate from blood]
    Tidsskr Nor Laegeforen, 116 (21), 2547-51
    PubMed 8928122
  3. Kongsgaard UE, Wang MY, Kvalheim G (1996)
    Leucocyte depletion filter removes cancer cells in human blood
    Acta Anaesthesiol Scand, 40 (1), 118-20
    PubMed 8904269
  4. Kvalheim G (1996)
    Detection of occult tumour cells in bone marrow and blood in breast cancer patients--methods and clinical significance
    Acta Oncol, 35 Suppl 8, 13-8
    PubMed 9073044
  5. Kvalheim G (1996)
    Purging of autografts: methods and clinical significance
    Ann Med, 28 (2), 167-73
    PubMed 8732646
  6. Kvalheim G, Holte H, Jakobsen E, Kvaloy S (1996)
    Immunomagnetic purging of lymphoma cells from autografts
    J Hematother, 5 (5), 561-2
    PubMed 8938530
  7. Kvalheim G, Wang MY, Pharo A, Holte H, Jacobsen E, Beiske K, Kvaløy S, Smeland E, Funderud S, Fodstad O (1996)
    Purging of tumor cells from leukapheresis products: experimental and clinical aspects
    J Hematother, 5 (4), 427-36
    PubMed 8877718

Publications 1995

  1. Deggerdal AH, Pettersen F, Kvalheim G, Hornes E, Smeland E, Fodstad O, Hovig E (1995)
    Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
    Lab Invest, 72 (4), 411-8
    PubMed 7723279
  2. Josefsen D, Waehre H, Paus E, Fosså SD (1995)
    Increase of serum prostatic specific antigen and clinical progression in pN + MO prostate cancer
    Br J Urol, 75 (4), 502-6
    PubMed 7540482
  3. Lundblad R, Wang MY, Kvalheim G, Lingaas E, Giercksky KE (1995)
    Granulocyte colony-stimulating factor improves myelopoiesis and host defense in fulminant intra-abdominal sepsis in rats
    Shock, 4 (1), 68-73
    PubMed 7552781
  4. Stacy RA, Espelund M, Saebøe-Larssen S, Hollung K, Helliesen E, Jakobsen KS (1995)
    Evolution of the Group 1 late embryogenesis abundant (Lea) genes: analysis of the Lea B19 gene family in barley
    Plant Mol Biol, 28 (6), 1039-54
    PubMed 7548822
  5. Wang MY, Fodstad O, Ludwig WD, Bengtsson M, Totterman T, Funderub S, Martin H, Kvalheim G (1995)
    An Effective, Direct Immunomagnetic Procedure for Purging Acute Lymphoblastic Leukemia Cells from Human Bone Marrow
    Pathol Oncol Res, 1 (1), 32-37
    PubMed 11173565

Publications 1994

  1. Andersson S, Saebøe-Larssen S, Lambertsson A, Merriam J, Jacobs-Lorena M (1994)
    A Drosophila third chromosome Minute locus encodes a ribosomal protein
    Genetics, 137 (2), 513-20
    PubMed 8070662
  2. Kavløy S, Holte H, Kvalheim G (1994)
    [High-dose autologous stem cell support in malignant diseases--an established method, uncertain indication]
    Tidsskr Nor Laegeforen, 114 (19), 2240-1
    PubMed 7992286
  3. Kvalheim G, Jakobsen E, Holte H, Beiske K, Langholm R, Høiby A, Wang MY, Funderund S, Fodstad O, Smeland E (1994)
    Autologous bone marrow transplantation of non-Hodgkin's lymphoma patients with marrow purged using immunomagnetic beads
    Prog Clin Biol Res, 389, 133-8
    PubMed 7700895
  4. Smeland EB, Rusten L, Jacobsen SE, Skrede B, Blomhoff R, Wang MY, Funderud S, Kvalheim G, Blomhoff HK (1994)
    All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells
    Blood, 84 (9), 2940-5
    PubMed 7524761
  5. Wang MY, Fodstad O, Funderud S, Bengtsson M, Totterman T, Ludwig WD, Martin H, Kvalheim G (1994)
    A direct and effective immunomagnetic method for bone marrow purging in non-T ALL malignancies. The use of an anti-HLA-DR antibody gives sustained engraftment
    Prog Clin Biol Res, 389, 119-24
    PubMed 7700893

Publications 1993

  1. Fiskerstrand T, Refsum H, Kvalheim G, Ueland PM (1993)
    Homocysteine and other thiols in plasma and urine: automated determination and sample stability
    Clin Chem, 39 (2), 263-71
    PubMed 8432015
  2. Josefsen D, Ous S, Høie J, Stenwig AE, Fosså SD (1993)
    Salvage treatment in male patients with germ cell tumours
    Br J Cancer, 67 (3), 568-72
    PubMed 8382512

Publications 1992

  1. Espelund M, Saebøe-Larssen S, Hughes DW, Galau GA, Larsen F, Jakobsen KS (1992)
    Late embryogenesis-abundant genes encoding proteins with different numbers of hydrophilic repeats are regulated differentially by abscisic acid and osmotic stress
    Plant J, 2 (2), 241-52
    PubMed 1302052
  2. Odegaard OR, Lindahl AK, Try K, Kvalheim G, Sørbø JH (1992)
    Recurrent venous thrombosis during warfarin treatment related to acquired protein S deficiency
    Thromb Res, 66 (6), 729-34
    PubMed 1519231
  3. Ogniben E, Hohaus S, Kvalheim G, Dörken B, Haas R (1992)
    Successful autologous transplantation of immunomagnetic bead purged bone marrow in non-Hodgkin's lymphoma
    Prog Clin Biol Res, 377, 189-95
    PubMed 1438415
  4. Rusten L, Kvaløy SO, Jakobsen E, Kvalheim G, Abrahamsen AF, Høiby EA, Sandven P, Lassen J, Bruu AL (1992)
    [Infection problems in the leukopenia phase after autologous bone marrow transplantation]
    Tidsskr Nor Laegeforen, 112 (13), 1723-6
    PubMed 1509434
    INT J CELL CLONING, 10 1, 108-110
  6. Smeland EB, Funderud S, Kvalheim G, Gaudernack G, Rasmussen AM, Rusten L, Wang MY, Tindle RW, Blomhoff HK, Egeland T (1992)
    Isolation and characterization of human hematopoietic progenitor cells: an effective method for positive selection of CD34+ cells
    Leukemia, 6 (8), 845-52
    PubMed 1379314
  7. Straka C, Kröner C, Dörken B, Kvalheim G (1992)
    Polymerase chain reaction monitoring shows a high efficacy of clinical immunomagnetic purging in patients with centroblastic-centrocytic non-Hodgkin's lymphoma
    Blood, 80 (10), 2688-90
    PubMed 1421385
  8. Wang MY, Kvalheim G, Kvaløy S, Beiske K, Jakobsen E, Wijdenes J, Pihl A, Fodstad O (1992)
    An effective immunomagnetic method for bone marrow purging in T cell malignancies
    Bone Marrow Transplant, 9 (5), 319-23
    PubMed 1617315

Publications 1991

  1. Körbling M, Knauf W, Funderud S, Kvalheim G, Hunstein W (1991)
    Autologous transplantation of an immunomagnetic bead purged marrow in patients with relapsed acute lymphoblastic leukemia
    Haematologica, 76 Suppl 1, 29-36
    PubMed 1650742

Publications 1990

  1. Storm-Mathisen I, Glomstein A, Lie SO, Albrechtsen D, Monclair T, Kvalheim G, Jacobsen AB (1990)
    [Autologous bone marrow transplantation in children--experience with neuroblastoma]
    Tidsskr Nor Laegeforen, 110 (19), 2513-6
    PubMed 2219008

Publications 1989

  1. Kvalheim G, Fjeld JG, Pihl A, Funderud S, Ugelstad J, Fodstad O, Nustad K (1989)
    Immunomagnetic removal of B-lymphoma cells using a novel mono-sized magnetizable polymer bead, M-280, in conjunction with primary IgM and IgG antibodies
    Bone Marrow Transplant, 4 (5), 567-74
    PubMed 2790334

Publications 1988

  1. Fodstad O, Kvalheim G, Pihl A, Godal A, Funderud S (1988)
    New indirect approach to the therapeutic use of immunotoxins
    J Natl Cancer Inst, 80 (6), 439-43
    PubMed 3259265
    Bone Marrow Transplant., 3 1, 97
  3. Kvalheim G, Funderud S, Kvaløy S, Gaudernack G, Beiske K, Jakobsen E, Jacobsen AB, Pihl A, Fodstad O (1988)
    Successful clinical use of an anti-HLA-DR monoclonal antibody for autologous bone marrow transplantation
    J Natl Cancer Inst, 80 (16), 1322-5
    PubMed 3050139
  4. Kvalheim G, Sørensen O, Fodstad O, Funderud S, Kiesel S, Dörken B, Nustad K, Jakobsen E, Ugelstad J, Pihl A (1988)
    Immunomagnetic removal of B-lymphoma cells from human bone marrow: a procedure for clinical use
    Bone Marrow Transplant, 3 (1), 31-41
    PubMed 3048468
  5. Oftung F, Mustafa AS, Shinnick TM, Houghten RA, Kvalheim G, Degre M, Lundin KE, Godal T (1988)
    Epitopes of the Mycobacterium tuberculosis 65-kilodalton protein antigen as recognized by human T cells
    J Immunol, 141 (8), 2749-54
    PubMed 2459228
  6. Tretli S, Kvalheim G, Thoresen S, Høst H (1988)
    Survival of breast cancer patients diagnosed during pregnancy or lactation
    Br J Cancer, 58 (3), 382-4
    PubMed 3179191

Publications 1987

    Bone Marrow Transplant., 2 2, 99-103
  2. Kiesel S, Haas R, Moldenhauer G, Kvalheim G, Pezzutto A, Dörken B (1987)
    Removal of cells from a malignant B-cell line from bone marrow with immunomagnetic beads and with complement and immunoglobulin switch variant mediated cytolysis
    Leuk Res, 11 (12), 1119-25
    PubMed 3320581
  3. Kvalheim G, Fodstad O, Pihl A, Nustad K, Pharo A, Ugelstad J, Funderud S (1987)
    Elimination of B-lymphoma cells from human bone marrow: model experiments using monodisperse magnetic particles coated with primary monoclonal antibodies
    Cancer Res, 47 (3), 846-51
    PubMed 3492268
    Bone Marrow Transplant., 2 2, 81-83
    Bone Marrow Transplant., 2 2, 94-98
  6. Vartdal F, Kvalheim G, Lea TE, Bosnes V, Gaudernack G, Ugelstad J, Albrechtsen D (1987)
    Depletion of T lymphocytes from human bone marrow. Use of magnetic monosized polymer microspheres coated with T-lymphocyte-specific monoclonal antibodies
    Transplantation, 43 (3), 366-71
    PubMed 3103274

Publications 1986

  1. Mustafa AS, Kvalheim G, Degre M, Godal T (1986)
    Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: antigen specificity and lymphokine production
    Infect Immun, 53 (3), 491-7
    PubMed 2427449

Publications 1985

  1. Kvalheim G, Gundersen S, Hager B, Fodstad O (1985)
    Intra-arterial infusion of mitomycin C in treatment of breast cancer: occurrence of skin necrosis in irradiated patients
    Radiother Oncol, 4 (2), 127-32
    PubMed 3934716
  2. Ueland PM, Kvalheim G, Lønning PE, Kvinnsland S (1985)
    Determination of warfarin in human plasma by high performance liquid chromatography and photodiode array detector
    Ther Drug Monit, 7 (3), 329-35
    PubMed 4049474

Publications 1984

  1. Fodstad O, Kvalheim G, Godal A, Lotsberg J, Aamdal S, Høst H, Pihl A (1984)
    Phase I study of the plant protein ricin
    Cancer Res, 44 (2), 862-5
    PubMed 6692385
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