Publications Section for Cellular Therapy

Publications published since 1984 from OUS - Section for Cellular Therapy

251 publications found

Publications 2021

  1. Aamdal E, Inderberg EM, Ellingsen EB, Rasch W, Brunsvig PF, Aamdal S, Heintz KM, Vodák D, Nakken S, Hovig E, Nyakas M, Guren TK, Gaudernack G (2021)
    Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
    Front Immunol, 12, 663865
    DOI 10.3389/fimmu.2021.663865, PubMed 34046035
  2. Caulier B, Enserink JM, Wälchli S (2021)
    Pharmacologic Control of CAR T Cells
    Int J Mol Sci, 22 (9)
    DOI 10.3390/ijms22094320, PubMed 33919245
  3. Dillard P, Casey N, Pollmann S, Vernhoff P, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2021)
    Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
    Oncoimmunology, 10 (1), 1936757
    DOI 10.1080/2162402X.2021.1936757, PubMed 34235003
  4. Flatmark K, Torgunrud A, Fleten KG, Davidson B, Juul HV, Mensali N, Lund-Andersen C, Inderberg EM (2021)
    Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei
    J Immunother Cancer, 9 (10)
    DOI 10.1136/jitc-2021-003109, PubMed 34711663
  5. Guldvik IJ, Ekseth L, Kishan AU, Stensvold A, Inderberg EM, Lilleby W (2021)
    Circulating Tumor Cell Persistence Associates with Long-Term Clinical Outcome to a Therapeutic Cancer Vaccine in Prostate Cancer
    J Pers Med, 11 (7)
    DOI 10.3390/jpm11070605, PubMed 34206815
  6. Heck A, Winge-Main AK (2021)
    Silent, isolated ACTH deficiency in malignant melanoma patients treated with immune checkpoint inhibitors
    BMJ Case Rep, 14 (5)
    DOI 10.1136/bcr-2021-241981, PubMed 34045201
  7. Ito J, Minemura T, Wälchli S, Niimi T, Fujihara Y, Kuroda S, Takimoto K, Maturana AD (2021)
    Id2 Represses Aldosterone-Stimulated Cardiac T-Type Calcium Channels Expression
    Int J Mol Sci, 22 (7)
    DOI 10.3390/ijms22073561, PubMed 33808082
  8. Mensali N, Dillard P, Fayzullin A, Köksal H, Gaudernack G, Kvalheim G, Inderberg EM, Wälchli S (2021)
    "Built-in" PD-1 blocker to rescue NK-92 activity from PD-L1-mediated tumor escape mechanisms
    FASEB J, 35 (9), e21750
    DOI 10.1096/fj.202100025R, PubMed 34424568
  9. Vestre K, Persiconi I, Borg Distefano M, Mensali N, Guadagno NA, Bretou M, Wälchli S, Arnold-Schrauf C, Bakke O, Dalod M, Lennon-Dumenil AM, Progida C (2021)
    Rab7b regulates dendritic cell migration by linking lysosomes to the actomyosin cytoskeleton
    J Cell Sci, 134 (18)
    DOI 10.1242/jcs.259221, PubMed 34494097

Publications 2020

  1. Bai B, Myklebust JH, Wälchli S (2020)
    Gene Editing in B-Lymphoma Cell Lines Using CRISPR/Cas9 Technology
    Methods Mol Biol, 2115, 445-454
    DOI 10.1007/978-1-0716-0290-4_25, PubMed 32006416
  2. Benard E, Casey NP, Inderberg EM, Wälchli S (2020)
    SJI 2020 special issue: A catalogue of Ovarian Cancer targets for CAR therapy
    Scand J Immunol, 92 (4), e12917
    DOI 10.1111/sji.12917, PubMed 32557659
  3. Brunsvig PF, Guren TK, Nyakas M, Steinfeldt-Reisse CH, Rasch W, Kyte JA, Juul HV, Aamdal S, Gaudernack G, Inderberg EM (2020)
    Long-Term Outcomes of a Phase I Study With UV1, a Second Generation Telomerase Based Vaccine, in Patients With Advanced Non-Small Cell Lung Cancer
    Front Immunol, 11, 572172
    DOI 10.3389/fimmu.2020.572172, PubMed 33324397
  4. Dillard P, Köksal H, Maggadottir SM, Winge-Main A, Pollmann S, Menard M, Myhre MR, Mælandsmo GM, Flørenes VA, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
    Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
    Mol Ther, 29 (3), 1199-1213
    DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301
  5. Dillard P, Lie M, Baken E, Lobert VH, Benard E, Köksal H, Inderberg EM, Wälchli S (2020)
    Colorectal cysts as a validating tool for CAR therapy
    BMC Biotechnol, 20 (1), 30
    DOI 10.1186/s12896-020-00623-0, PubMed 32487146
  6. Inderberg EM, Wälchli S (2020)
    Long-term surviving cancer patients as a source of therapeutic TCR
    Cancer Immunol Immunother, 69 (5), 859-865
    DOI 10.1007/s00262-019-02468-9, PubMed 31915853
  7. Inderberg EM, Wälchli S (2020)
    Sympathetic improvement of cancer vaccine efficacy
    Hum Vaccin Immunother, 16 (8), 1888-1890
    DOI 10.1080/21645515.2019.1703456, PubMed 31977269
  8. Kierulf-Vieira KS, Sandberg CJ, Waaler J, Lund K, Skaga E, Saberniak BM, Panagopoulos I, Brandal P, Krauss S, Langmoen IA, Vik-Mo EO (2020)
    A Small-Molecule Tankyrase Inhibitor Reduces Glioma Stem Cell Proliferation and Sphere Formation
    Cancers (Basel), 12 (6)
    DOI 10.3390/cancers12061630, PubMed 32575464
  9. Köksal H, Dillard P, Juzeniene A, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S (2020)
    Combinatorial CAR design improves target restriction
    J Biol Chem, 296, 100116
    DOI 10.1074/jbc.RA120.016234, PubMed 33234592
  10. Lichtenegger FS, Schnorfeil FM, Rothe M, Deiser K, Altmann T, Bücklein VL, Köhnke T, Augsberger C, Konstandin NP, Spiekermann K, Moosmann A, Boehm S, Boxberg M, Heemskerk MH, Goerlich D, Wittmann G, Wagner B, Hiddemann W, Schendel DJ, Kvalheim G, Bigalke I, Subklewe M (2020)
    Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: results of a phase I trial
    Clin Transl Immunology, 9 (3), e1117
    DOI 10.1002/cti2.1117, PubMed 32153780
  11. Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
    Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
    Cancer Immunol Immunother, 69 (1), 159-161
    DOI 10.1007/s00262-019-02409-6, PubMed 31776597
  12. Wälchli S, Sioud M (2020)
    Next Generation of Adoptive T Cell Therapy Using CRISPR/Cas9 Technology: Universal or Boosted?
    Methods Mol Biol, 2115, 407-417
    DOI 10.1007/978-1-0716-0290-4_22, PubMed 32006413
  13. Weum Abrahamsen I, Grønvold BC, Inderberg EM, Mensali N, Mattsson J, Gedde-Dahl T (2020)
    Posttransplantation Lymphoproliferative Disease Treated by Retransplantation
    Case Reports Immunol, 2020, 9403123
    DOI 10.1155/2020/9403123, PubMed 32158568
  14. Winge-Main AK, Wälchli S, Inderberg EM (2020)
    T cell receptor therapy against melanoma-Immunotherapy for the future?
    Scand J Immunol, 92 (4), e12927
    DOI 10.1111/sji.12927, PubMed 32640053

Publications 2019

  1. Andersson Y, Inderberg EM, Kvalheim G, Herud TM, Engebraaten O, Flatmark K, Dueland S, Fodstad Ø (2019)
    Immune stimulatory effect of anti-EpCAM immunotoxin - improved overall survival of metastatic colorectal cancer patients
    Acta Oncol, 59 (4), 404-409
    DOI 10.1080/0284186X.2019.1704864, PubMed 31876430
  2. Camilio KA, Wang MY, Mauseth B, Waagene S, Kvalheim G, Rekdal Ø, Sveinbjørnsson B, Mælandsmo GM (2019)
    Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model
    Breast Cancer Res, 21 (1), 9
    DOI 10.1186/s13058-018-1092-x, PubMed 30670061
  3. Josefsson SE, Beiske K, Blaker YN, Førsund MS, Holte H, Østenstad B, Kimby E, Köksal H, Wälchli S, Bai B, Smeland EB, Levy R, Kolstad A, Huse K, Myklebust JH (2019)
    TIGIT and PD-1 Mark Intratumoral T Cells with Reduced Effector Function in B-cell Non-Hodgkin Lymphoma
    Cancer Immunol Res, 7 (3), 355-362
    DOI 10.1158/2326-6066.CIR-18-0351, PubMed 30659053
  4. Köksal H, Baken E, Warren DJ, Løset GÅ, Inderberg EM, Wälchli S (2019)
    Chimeric antigen receptor preparation from hybridoma to T-cell expression
    Antib Ther, 2 (2), 56-63
    DOI 10.1093/abt/tbz007, PubMed 33928223
  5. Köksal H, Dillard P, Josefsson SE, Maggadottir SM, Pollmann S, Fåne A, Blaker YN, Beiske K, Huse K, Kolstad A, Holte H, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S (2019)
    Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma
    Blood Adv, 3 (8), 1230-1243
    DOI 10.1182/bloodadvances.2018029678, PubMed 30979721
  6. Köksal H, Müller E, Inderberg EM, Bruland Ø, Wälchli S (2019)
    Treating osteosarcoma with CAR T cells
    Scand J Immunol, 89 (3), e12741
    DOI 10.1111/sji.12741, PubMed 30549299
  7. Kyte JA, Fåne A, Pule M, Gaudernack G (2019)
    Transient redirection of T cells for adoptive cell therapy with telomerase-specific T helper cell receptors isolated from long term survivors after cancer vaccination
    Oncoimmunology, 8 (4), e1565236
    DOI 10.1080/2162402X.2019.1565236, PubMed 30906659
  8. Mensali N, Dillard P, Hebeisen M, Lorenz S, Theodossiou T, Myhre MR, Fåne A, Gaudernack G, Kvalheim G, Myklebust JH, Inderberg EM, Wälchli S (2019)
    NK cells specifically TCR-dressed to kill cancer cells
    EBioMedicine, 40, 106-117
    DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853
  9. Mensali N, Grenov A, Pati NB, Dillard P, Myhre MR, Gaudernack G, Kvalheim G, Inderberg EM, Bakke O, Wälchli S (2019)
    Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
    Oncoimmunology, 8 (3), 1558663
    DOI 10.1080/2162402X.2018.1558663, PubMed 30723591
  10. Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2019)
    Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
    Cancer Immunol Immunother, 68 (8), 1235-1243
    DOI 10.1007/s00262-019-02356-2, PubMed 31214732
  11. Theodossiou TA, Ali M, Grigalavicius M, Grallert B, Dillard P, Schink KO, Olsen CE, Wälchli S, Inderberg EM, Kubin A, Peng Q, Berg K (2019)
    Simultaneous defeat of MCF7 and MDA-MB-231 resistances by a hypericin PDT-tamoxifen hybrid therapy
    NPJ Breast Cancer, 5, 13
    DOI 10.1038/s41523-019-0108-8, PubMed 30993194

Publications 2018

  1. Dillard P, Köksal H, Inderberg EM, Wälchli S (2018)
    A Spheroid Killing Assay by CAR T Cells
    J Vis Exp (142)
    DOI 10.3791/58785, PubMed 30596389
  2. Lampen MH, Uchtenhagen H, Blom K, Varnaitė R, Pakalniene J, Dailidyte L, Wälchli S, Lindquist L, Mickiene A, Michaëlsson J, Schumacher TN, Ljunggren HG, Sandberg JK, Achour A, Gredmark-Russ S (2018)
    Breadth and Dynamics of HLA-A2- and HLA-B7-Restricted CD8+ T Cell Responses against Nonstructural Viral Proteins in Acute Human Tick-Borne Encephalitis Virus Infection
    Immunohorizons, 2 (6), 172-184
    DOI 10.4049/immunohorizons.1800029, PubMed 31022685
  3. Våtsveen TK, Myhre MR, Steen CB, Wälchli S, Lingjærde OC, Bai B, Dillard P, Theodossiou TA, Holien T, Sundan A, Inderberg EM, Smeland EB, Myklebust JH, Oksvold MP (2018)
    Artesunate shows potent anti-tumor activity in B-cell lymphoma
    J Hematol Oncol, 11 (1), 23
    DOI 10.1186/s13045-018-0561-0, PubMed 29458389

Publications 2017

  1. Bollum LK, Huse K, Oksvold MP, Bai B, Hilden VI, Forfang L, Yoon SO, Wälchli S, Smeland EB, Myklebust JH (2017)
    BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5
    PLoS One, 12 (5), e0177188
    DOI 10.1371/journal.pone.0177188, PubMed 28489883
  2. Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2017)
    The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
    Pathol Oncol Res, 25 (1), 255-262
    DOI 10.1007/s12253-017-0355-7, PubMed 29098521
  3. Giustacchini A, Thongjuea S, Barkas N, Woll PS, Povinelli BJ, Booth CAG, Sopp P, Norfo R, Rodriguez-Meira A, Ashley N, Jamieson L, Vyas P, Anderson K, Segerstolpe Å, Qian H, Olsson-Strömberg U, Mustjoki S, Sandberg R, Jacobsen SEW, Mead AJ (2017)
    Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia
    Nat Med, 23 (6), 692-702
    DOI 10.1038/nm.4336, PubMed 28504724
  4. Inderberg EM, Mensali N, Oksvold MP, Fallang LE, Fåne A, Skorstad G, Stenvik GE, Progida C, Bakke O, Kvalheim G, Myklebust JH, Wälchli S (2017)
    Human c-SRC kinase (CSK) overexpression makes T cells dummy
    Cancer Immunol Immunother, 67 (4), 525-536
    DOI 10.1007/s00262-017-2105-9, PubMed 29248956
  5. Inderberg EM, Wälchli S, Myhre MR, Trachsel S, Almåsbak H, Kvalheim G, Gaudernack G (2017)
    T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
    Oncoimmunology, 6 (4), e1302631
    DOI 10.1080/2162402X.2017.1302631, PubMed 28507809
  6. Josefsson SE, Huse K, Kolstad A, Beiske K, Pende D, Steen CB, Inderberg EM, Lingjærde OC, Østenstad B, Smeland EB, Levy R, Irish JM, Myklebust JH (2017)
    T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling
    Clin Cancer Res, 24 (4), 870-881
    DOI 10.1158/1078-0432.CCR-17-2337, PubMed 29217528
  7. Koksal H, Walchli S (2017)
    Fishing therapeutic T-cell receptors in healthy donor blood, is safety predictable?
    Transl. Cancer Res., 6 3, S622-S624
    DOI 10.21037/tcr.2017.05.25
  8. Li X, Lu J, Kan Q, Li X, Fan Q, Li Y, Huang R, Slipicevic A, Dong HP, Eide L, Wang J, Zhang H, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
    Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
    Sci Rep, 7 (1), 5081
    DOI 10.1038/s41598-017-05086-6, PubMed 28698547
  9. Lilleby W, Gaudernack G, Brunsvig PF, Vlatkovic L, Schulz M, Mills K, Hole KH, Inderberg EM (2017)
    Phase I/IIa clinical trial of a novel hTERT peptide vaccine in men with metastatic hormone-naive prostate cancer
    Cancer Immunol Immunother, 66 (7), 891-901
    DOI 10.1007/s00262-017-1994-y, PubMed 28391357
  10. Morris JL, Fane A, Sarovich DS, Price EP, Rush CM, Govan BL, Parker E, Mayo M, Currie BJ, Ketheesan N (2017)
    Increased Neurotropic Threat from Burkholderia pseudomallei Strains with a B. mallei-like Variation in the bimA Motility Gene, Australia
    Emerg Infect Dis, 23 (5)
    DOI 10.3201/eid2305.151417, PubMed 28418830
  11. Nestvold J, Wang MY, Camilio KA, Zinöcker S, Tjelle TE, Lindberg A, Haug BE, Kvalheim G, Sveinbjørnsson B, Rekdal Ø (2017)
    Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model
    Oncoimmunology, 6 (8), e1338236
    DOI 10.1080/2162402X.2017.1338236, PubMed 28920000
  12. Schive SW, Mirlashari MR, Hasvold G, Wang M, Josefsen D, Gullestad HP, Korsgren O, Foss A, Kvalheim G, Scholz H (2017)
    Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
    Cell Med, 9 (3), 103-116
    DOI 10.3727/215517917X693401, PubMed 28713640
  13. Walseng E, Köksal H, Sektioglu IM, Fåne A, Skorstad G, Kvalheim G, Gaudernack G, Inderberg EM, Wälchli S (2017)
    A TCR-based Chimeric Antigen Receptor
    Sci Rep, 7 (1), 10713
    DOI 10.1038/s41598-017-11126-y, PubMed 28878363

Publications 2016

  1. Belnoue E, Di Berardino-Besson W, Gaertner H, Carboni S, Dunand-Sauthier I, Cerini F, Suso-Inderberg EM, Wälchli S, König S, Salazar AM, Hartley O, Dietrich PY, Walker PR, Derouazi M (2016)
    Enhancing Antitumor Immune Responses by Optimized Combinations of Cell-penetrating Peptide-based Vaccines and Adjuvants
    Mol Ther, 24 (9), 1675-85
    DOI 10.1038/mt.2016.134, PubMed 27377043
  2. Carretero R, Sektioglu IM, Garbi N, Salgado OC, Beckhove P, Hämmerling GJ (2016)
    Corrigendum: Eosinophils orchestrate cancer rejection by normalizing tumor vessels and enhancing infiltration of CD8(+) T cells
    Nat Immunol, 17 (2), 214
    DOI 10.1038/ni0216-214b, PubMed 26784268
  3. Eide HA, Halvorsen AR, Sandhu V, Fåne A, Berg J, Haakensen VD, Kure EH, Brustugun OT, Kiserud CE, Kyte JA, Helland Å (2016)
    Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease
    Clin Transl Immunology, 5 (11), e109
    DOI 10.1038/cti.2016.65, PubMed 27990285
  4. Elvsåshagen T, Zuzarte P, Westlye LT, Bøen E, Josefsen D, Boye B, Hol PK, Malt UF, Young LT, Andreazza AC (2016)
    Dentate gyrus-cornu ammonis (CA) 4 volume is decreased and associated with depressive episodes and lipid peroxidation in bipolar II disorder: Longitudinal and cross-sectional analyses
    Bipolar Disord, 18 (8), 657-668
    DOI 10.1111/bdi.12457, PubMed 27995733
  5. Kyte JA, Aamdal S, Dueland S, Sæbøe-Larsen S, Inderberg EM, Madsbu UE, Skovlund E, Gaudernack G, Kvalheim G (2016)
    Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
    Oncoimmunology, 5 (11), e1232237
    DOI 10.1080/2162402X.2016.1232237, PubMed 27999747
  6. Kyte JA, Gaudernack G, Faane A, Lislerud K, Inderberg EM, Brunsvig P, Aamdal S, Kvalheim G, Wälchli S, Pule M (2016)
    T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
    Oncoimmunology, 5 (12), e1249090
    DOI 10.1080/2162402X.2016.1249090, PubMed 28123886
  7. Li J, Maggadottir SM, Hakonarson H (2016)
    Are genetic tests informative in predicting food allergy?
    Curr Opin Allergy Clin Immunol, 16 (3), 257-64
    DOI 10.1097/ACI.0000000000000268, PubMed 27070332
  8. Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen RG, Peng Q, Wang J, Zhang H, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2016)
    MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
    Oncotarget, 7 (26), 40297-40313
    DOI 10.18632/oncotarget.9610, PubMed 27248169
  9. Mensali N, Ying F, Sheng VO, Yang W, Walseng E, Kumari S, Fallang LE, Kolstad A, Uckert W, Malmberg KJ, Wälchli S, Olweus J (2016)
    Targeting B-cell neoplasia with T-cell receptors recognizing a CD20-derived peptide on patient-specific HLA
    Oncoimmunology, 5 (5), e1138199
    DOI 10.1080/2162402X.2016.1138199, PubMed 27467957
  10. Myklebust JH, Brody J, Kohrt HE, Kolstad A, Czerwinski DK, Wälchli S, Green MR, Trøen G, Liestøl K, Beiske K, Houot R, Delabie J, Alizadeh AA, Irish JM, Levy R (2016)
    Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling
    Blood, 129 (6), 759-770
    DOI 10.1182/blood-2016-05-718494, PubMed 28011673
  11. Schive SW, Foss A, Sahraoui A, Kloster-Jensen K, Hafsahl G, Kvalheim G, Lundgren T, von Zur-Mühlen B, Felldin M, Rafael E, Lempinen M, Korsgren O, Jenssen TG, Mishra V, Scholz H (2016)
    Cost and clinical outcome of islet transplantation in Norway 2010-2015
    Clin Transplant, 31 (1)
    DOI 10.1111/ctr.12871, PubMed 27862341
  12. Sioud M, Nyakas M, Sæbøe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G (2016)
    Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
    Case Rep Med, 2016, 9639585
    DOI 10.1155/2016/9639585, PubMed 27504122

Publications 2015

  1. Almåsbak H, Walseng E, Kristian A, Myhre MR, Suso EM, Munthe LA, Andersen JT, Wang MY, Kvalheim G, Gaudernack G, Kyte JA (2015)
    Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model
    Gene Ther, 22 (5), 391-403
    DOI 10.1038/gt.2015.4, PubMed 25652098
  2. Eide N, Faye RS, Høifødt HK, Sandstad B, Qvale G, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2015)
    Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox
    Acta Ophthalmol, 93 (1), 59-66
    DOI 10.1111/aos.12462, PubMed 25613126
  3. Naderi EH, Skah S, Ugland H, Myklebost O, Sandnes DL, Torgersen ML, Josefsen D, Ruud E, Naderi S, Blomhoff HK (2015)
    Bone marrow stroma-derived PGE2 protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death
    Mol Cancer, 14, 14
    DOI 10.1186/s12943-014-0278-9, PubMed 25623255
  4. Sioud M, Mobergslien A, Sæbøe-Larssen S (2015)
    Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses
    Methods Mol Biol, 1218, 269-76
    DOI 10.1007/978-1-4939-1538-5_16, PubMed 25319657
  5. Tadesse FG, Mensali N, Fallang LE, Walseng E, Yang W, Olweus J, Wälchli S (2015)
    Unpredicted phenotypes of two mutants of the TcR DMF5
    J Immunol Methods, 425, 37-44
    DOI 10.1016/j.jim.2015.06.006, PubMed 26079729
  6. Theodossiou TA, Wälchli S, Olsen CE, Skarpen E, Berg K (2015)
    Deciphering the Nongenomic, Mitochondrial Toxicity of Tamoxifens As Determined by Cell Metabolism and Redox Activity
    ACS Chem Biol, 11 (1), 251-62
    DOI 10.1021/acschembio.5b00734, PubMed 26569462
  7. Yu D, Zhong Y, Li X, Li Y, Li X, Cao J, Fan H, Yuan Y, Ji Z, Qiao B, Wen JG, Zhang M, Kvalheim G, Nesland JM, Suo Z (2015)
    ILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro
    Oncotarget, 6 (40), 42687-703
    DOI 10.18632/oncotarget.5883, PubMed 26528857

Publications 2014

  1. Husøy MA, Brinch L, Tjønnfjord GE, Gedde-Dahl T, Heldal D, Holme PA, Dybedal I, Kolstad A, Akkök ÇA, Rollag H, Gaustad P, Bergan S, Egeland T, Josefsen D, Kvalheim G, Fløisand Y (2014)
    [Allogeneic stem-cell transplantation in adults 1985-2012: results and development]
    Tidsskr Nor Laegeforen, 134 (16), 1569-75
    DOI 10.4045/tidsskr.13.1415, PubMed 25178233
  2. Kolb HJ, Schmetzer H, Schmid C, Bigalke I, Buhmann R, Moosmann A, Falk C, Reuther S, Schuster F, Borkhardt A (2014)
    Mechanisms of graft-versus-leukemia effects after allogeneic stem cell transplantation: effects on the leukemia stem cell?
    Leuk Suppl, 3 (Suppl 1), S16-7
    DOI 10.1038/leusup.2014.9, PubMed 27175264
  3. Skårn M, Noordhuis P, Wang MY, Veuger M, Kresse SH, Egeland EV, Micci F, Namløs HM, Håkelien AM, Olafsrud SM, Lorenz S, Haraldsen G, Kvalheim G, Meza-Zepeda LA, Myklebost O (2014)
    Generation and characterization of an immortalized human mesenchymal stromal cell line
    Stem Cells Dev, 23 (19), 2377-89
    DOI 10.1089/scd.2013.0599, PubMed 24857590
  4. Subklewe M, Geiger C, Lichtenegger FS, Javorovic M, Kvalheim G, Schendel DJ, Bigalke I (2014)
    New generation dendritic cell vaccine for immunotherapy of acute myeloid leukemia
    Cancer Immunol Immunother, 63 (10), 1093-103
    DOI 10.1007/s00262-014-1600-5, PubMed 25186611
  5. Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P et al. (2014)
    Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
    Cancer Cell, 25 (6), 794-808
    DOI 10.1016/j.ccr.2014.03.036, PubMed 24835589

Publications 2013

  1. Dominguez-Valentin M, Nilbert M, Wernhoff P, López-Köstner F, Vaccaro C, Sarroca C, Palmero EI, Giraldo A, Ashton-Prolla P, Alvarez K, Ferro A, Neffa F, Caris J, Carraro DM, Rossi BM (2013)
    Mutation spectrum in South American Lynch syndrome families
    Hered Cancer Clin Pract, 11 (1), 18
    DOI 10.1186/1897-4287-11-18, PubMed 24344984
  2. Gunnlaugsdottir B, Maggadottir SM, Skaftadottir I, Ludviksson BR (2013)
    The ex vivo induction of human CD103⁺ CD25hi Foxp3⁺ CD4⁺ and CD8⁺ Tregs is IL-2 and TGF-β1 dependent
    Scand J Immunol, 77 (2), 125-34
    DOI 10.1111/sji.12009, PubMed 23126599
  3. Kaur K, Mirlashari MR, Kvalheim G, Kjeldsen-Kragh J (2013)
    3',4'-Dimethoxyflavone and valproic acid promotes the proliferation of human hematopoietic stem cells
    Stem Cell Res Ther, 4 (3), 60
    DOI 10.1186/scrt208, PubMed 23706670
  4. Liu Y, Wu X, Li X, Kvalheim G, Axcrona U, Axcrona K, Suo Z (2013)
    Blocking mtDNA replication upregulates the expression of stemness-related genes in prostate cancer cell lines
    Ultrastruct Pathol, 37 (4), 258-66
    DOI 10.3109/01913123.2013.770112, PubMed 23634795
  5. Ma Y, Liang D, Liu J, Wen JG, Servoll E, Waaler G, Sæter T, Axcrona K, Vlatkovic L, Axcrona U, Paus E, Yang Y, Zhang Z, Kvalheim G, Nesland JM, Suo Z (2013)
    SHBG is an important factor in stemness induction of cells by DHT in vitro and associated with poor clinical features of prostate carcinomas
    PLoS One, 8 (7), e70558 (Retracted)
    DOI 10.1371/journal.pone.0070558, PubMed 23936228
  6. Mustjoki S, Richter J, Barbany G, Ehrencrona H, Fioretos T, Gedde-Dahl T, Gjertsen BT, Hovland R, Hernesniemi S, Josefsen D, Koskenvesa P, Dybedal I, Markevärn B, Olofsson T, Olsson-Strömberg U, Rapakko K, Thunberg S, Stenke L, Simonsson B, Porkka K, Hjorth-Hansen H, Nordic CML Study Group (NCMLSG) (2013)
    Impact of malignant stem cell burden on therapy outcome in newly diagnosed chronic myeloid leukemia patients
    Leukemia, 27 (7), 1520-6
    DOI 10.1038/leu.2013.19, PubMed 23328954
  7. Naderi EH, Ugland HK, Diep PP, Josefsen D, Ruud E, Naderi S, Blomhoff HK (2013)
    Selective inhibition of cell death in malignant vs normal B-cell precursors: implications for cAMP in development and treatment of BCP-ALL
    Blood, 121 (10), 1805-13
    DOI 10.1182/blood-2012-08-452698, PubMed 23299313
  8. Pi F, Dillard P, Limozin L, Charrier A, Sengupta K (2013)
    Nanometric protein-patch arrays on glass and polydimethylsiloxane for cell adhesion studies
    Nano Lett, 13 (7), 3372-8
    DOI 10.1021/nl401696m, PubMed 23808889
  9. Rud AK, Borgen E, Mælandsmo GM, Flatmark K, Le H, Josefsen D, Solvoll I, Schirmer CB, Helland Å, Jørgensen L, Brustugun OT, Fodstad Ø, Boye K (2013)
    Clinical significance of disseminated tumour cells in non-small cell lung cancer
    Br J Cancer, 109 (5), 1264-70
    DOI 10.1038/bjc.2013.450, PubMed 23942067
  10. Sioud M, Saebøe-Larssen S, Hetland TE, Kaern J, Mobergslien A, Kvalheim G (2013)
    Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients
    Int J Oncol, 43 (1), 280-8
    DOI 10.3892/ijo.2013.1922, PubMed 23620105
  11. Sioud M, Skorstad G, Mobergslien A, Sæbøe-Larssen S (2013)
    A novel peptide carrier for efficient targeting of antigens and nucleic acids to dendritic cells
    FASEB J, 27 (8), 3272-83
    DOI 10.1096/fj.12-224758, PubMed 23671272
  12. Vik-Mo EO, Nyakas M, Mikkelsen BV, Moe MC, Due-Tønnesen P, Suso EM, Sæbøe-Larssen S, Sandberg C, Brinchmann JE, Helseth E, Rasmussen AM, Lote K, Aamdal S, Gaudernack G, Kvalheim G, Langmoen IA (2013)
    Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
    Cancer Immunol Immunother, 62 (9), 1499-509
    DOI 10.1007/s00262-013-1453-3, PubMed 23817721
  13. Wang P, Gao Q, Suo Z, Munthe E, Solberg S, Ma L, Wang M, Westerdaal NA, Kvalheim G, Gaudernack G (2013)
    Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines
    PLoS One, 8 (3), e57020 (Retracted)
    DOI 10.1371/journal.pone.0057020, PubMed 23469181
  14. Wang P, Suo Z, Wang M, Høifødt HK, Fodstad O, Gaudernack G, Kvalheim G (2013)
    In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines
    Exp Hematol Oncol, 2 (1), 16
    DOI 10.1186/2162-3619-2-16, PubMed 23738757

Publications 2012

  1. Fløisand Y, Brinch L, Gedde-Dahl T, Tjønnfjord GE, Dybedal I, Holte H, Heldal D, Torfoss D, Aurlien E, Lauritzsen GF, Fosså A, Lehne G, Baggerød E, Kvalheim G, Egeland T, Bishop MR, Fowler DH, Kolstad A (2012)
    Ultra-short course sirolimus contributes to effective GVHD prophylaxis after reduced-intensity allogeneic hematopoietic cell transplantation
    Bone Marrow Transplant, 47 (12), 1552-7
    DOI 10.1038/bmt.2012.63, PubMed 22522568
  2. Huse K, Bakkebø M, Wälchli S, Oksvold MP, Hilden VI, Forfang L, Bredahl ML, Liestøl K, Alizadeh AA, Smeland EB, Myklebust JH (2012)
    Role of Smad proteins in resistance to BMP-induced growth inhibition in B-cell lymphoma
    PLoS One, 7 (10), e46117
    DOI 10.1371/journal.pone.0046117, PubMed 23049692
  3. Johnson E, Førland DT, Hetland G, Sætre L, Olstad OK, Lyberg T (2012)
    Effect of AndoSan™ on expression of adhesion molecules and production of reactive oxygen species in human monocytes and granulocytes in vivo
    Scand J Gastroenterol, 47 (8-9), 984-92
    DOI 10.3109/00365521.2012.660544, PubMed 22564240
  4. Langmoen IA, Foss A, Kvalheim G, Engebretsen L, Glover JC (2012)
    [Stem cell research--new hope?]
    Tidsskr Nor Laegeforen, 132 (23-24), 2584
    DOI 10.4045/tidsskr.12.1324, PubMed 23338066
  5. Ma Y, Liang D, Liu J, Axcrona K, Kvalheim G, Giercksky KE, Nesland JM, Suo Z (2012)
    Synergistic effect of SCF and G-CSF on stem-like properties in prostate cancer cell lines
    Tumour Biol, 33 (4), 967-78
    DOI 10.1007/s13277-012-0325-3, PubMed 22252524
  6. Mathiesen RR, Borgen E, Renolen A, Løkkevik E, Nesland JM, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Kvalheim G, Lønning PE, Naume B (2012)
    Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
    Breast Cancer Res, 14 (4), R117
    DOI 10.1186/bcr3242, PubMed 22889108

Publications 2011

  1. Eide MB, Lauritzsen GF, Kvalheim G, Kolstad A, Fagerli UM, Maisenhölder M, Østenstad B, Fluge Ø, Delabie J, Aarset H, Liestøl K, Holte H (2011)
    High dose chemotherapy with autologous stem cell support for patients with histologically transformed B-cell non-Hodgkin lymphomas. A Norwegian multi centre phase II study
    Br J Haematol, 152 (5), 600-10
    DOI 10.1111/j.1365-2141.2010.08519.x, PubMed 21241276
  2. Elvsåshagen T, Vera E, Bøen E, Bratlie J, Andreassen OA, Josefsen D, Malt UF, Blasco MA, Boye B (2011)
    The load of short telomeres is increased and associated with lifetime number of depressive episodes in bipolar II disorder
    J Affect Disord, 135 (1-3), 43-50
    DOI 10.1016/j.jad.2011.08.006, PubMed 21880373
  3. Førland DT, Johnson E, Saetre L, Lyberg T, Lygren I, Hetland G (2011)
    Effect of an extract based on the medicinal mushroom Agaricus blazei Murill on expression of cytokines and calprotectin in patients with ulcerative colitis and Crohn's disease
    Scand J Immunol, 73 (1), 66-75
    DOI 10.1111/j.1365-3083.2010.02477.x, PubMed 21129005
  4. Hetland G, Johnson E, Lyberg T, Kvalheim G (2011)
    The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation
    Adv Pharmacol Sci, 2011, 157015
    DOI 10.1155/2011/157015, PubMed 21912538
  5. Huijbers IJ, Soudja SM, Uyttenhove C, Buferne M, Inderberg-Suso EM, Colau D, Pilotte L, Powis de Tenbossche CG, Chomez P, Brasseur F, Schmitt-Verhulst AM, Van den Eynde BJ (2011)
    Minimal tolerance to a tumor antigen encoded by a cancer-germline gene
    J Immunol, 188 (1), 111-21
    DOI 10.4049/jimmunol.1002612, PubMed 22140254
  6. Josefsen D, Forfang L, Dyrhaug M, Blystad AK, Stokke T, Smeland EB, Kvalheim G (2011)
    Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy
    Eur J Haematol, 87 (6), 494-502
    DOI 10.1111/j.1600-0609.2011.01681.x, PubMed 21752097
  7. Ma Y, Liang D, Liu J, Axcrona K, Kvalheim G, Stokke T, Nesland JM, Suo Z (2011)
    Prostate cancer cell lines under hypoxia exhibit greater stem-like properties
    PLoS One, 6 (12), e29170 (Retracted)
    DOI 10.1371/journal.pone.0029170, PubMed 22216200
  8. Mohty M, Duarte RF, Croockewit S, Hübel K, Kvalheim G, Russell N (2011)
    The role of plerixafor in optimizing peripheral blood stem cell mobilization for autologous stem cell transplantation
    Leukemia, 25 (1), 1-6
    DOI 10.1038/leu.2010.224, PubMed 21224858
  9. Suso EM, Dueland S, Rasmussen AM, Vetrhus T, Aamdal S, Kvalheim G, Gaudernack G (2011)
    hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
    Cancer Immunol Immunother, 60 (6), 809-18
    DOI 10.1007/s00262-011-0991-9, PubMed 21365467
  10. Torfoss D, Sandstad B, Mollnes TE, Høiby EA, Holte H, Bjerner J, Bjøro T, Gaudernack G, Kvalheim G, Kvaløy S (2011)
    The mild inflammatory response in febrile neutropenic lymphoma patients with low risk of complications is more pronounced in patients receiving tobramycin once daily compared with three times daily
    Scand J Immunol, 74 (6), 632-9
    DOI 10.1111/j.1365-3083.2011.02618.x, PubMed 21883353
  11. Zinöcker S, Wang MY, Gaustad P, Kvalheim G, Rolstad B, Vaage JT (2011)
    Mycoplasma contamination revisited: mesenchymal stromal cells harboring Mycoplasma hyorhinis potently inhibit lymphocyte proliferation in vitro
    PLoS One, 6 (1), e16005
    DOI 10.1371/journal.pone.0016005, PubMed 21264307

Publications 2010

  1. Almåsbak H, Rian E, Hoel HJ, Pulè M, Wälchli S, Kvalheim G, Gaudernack G, Rasmussen AM (2010)
    Transiently redirected T cells for adoptive transfer
    Cytotherapy, 13 (5), 629-40
    DOI 10.3109/14653249.2010.542461, PubMed 21174490
  2. Jantunen E, Kvalheim G (2010)
    Mobilization strategies in hard-to-mobilize patients with lymphoid malignancies
    Eur J Haematol, 85 (6), 463-71
    DOI 10.1111/j.1600-0609.2010.01520.x, PubMed 20738393
  3. Johnsen HE, Geisler C, Juvonen E, Remes K, Juliusson G, Hörnsten P, Kvaloy S, Kvalheim G, Jürgensen GW, Pedersen LM, Bergmann OJ, Schmitz A, Boegsted M (2010)
    Priming with r-metHuSCF and filgrastim or chemotherapy and filgrastim in patients with malignant lymphomas: a randomized phase II pilot study of mobilization and engraftment
    Bone Marrow Transplant, 46 (1), 44-51
    DOI 10.1038/bmt.2010.84, PubMed 20436517
  4. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Stromberg M, Wiedswang G, Kvalheim G, Karesen R, Nesland JM, Borresen-Dale AL, Sorlie T (2010)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
    Mol. Oncol., 4 (2), 169
    DOI 10.1016/j.molonc.2010.01.003
  5. Rasmussen AM, Borelli G, Hoel HJ, Lislerud K, Gaudernack G, Kvalheim G, Aarvak T (2010)
    Ex vivo expansion protocol for human tumor specific T cells for adoptive T cell therapy
    J Immunol Methods, 355 (1-2), 52-60
    DOI 10.1016/j.jim.2010.02.004, PubMed 20171968
  6. Revheim ME, Winge-Main AK, Hagen G, Fjeld JG, Fosså SD, Lilleby W (2010)
    Combined positron emission tomography/computed tomography in sunitinib therapy assessment of patients with metastatic renal cell carcinoma
    Clin Oncol (R Coll Radiol), 23 (5), 339-43
    DOI 10.1016/j.clon.2010.11.006, PubMed 21134733
  7. Tamburstuen MV, Reppe S, Spahr A, Sabetrasekh R, Kvalheim G, Slaby I, Syversen U, Lyngstadaas SP, Reseland JE (2010)
    Ameloblastin promotes bone growth by enhancing proliferation of progenitor cells and by stimulating immunoregulators
    Eur J Oral Sci, 118 (5), 451-9
    DOI 10.1111/j.1600-0722.2010.00760.x, PubMed 20831578
  8. Tamburstuen MV, Reseland JE, Spahr A, Brookes SJ, Kvalheim G, Slaby I, Snead ML, Lyngstadaas SP (2010)
    Ameloblastin expression and putative autoregulation in mesenchymal cells suggest a role in early bone formation and repair
    Bone, 48 (2), 406-13
    DOI 10.1016/j.bone.2010.09.007, PubMed 20854943

Publications 2009

  1. Eide N, Faye RS, Høifødt HK, Øvergaard R, Jebsen P, Kvalheim G, Fodstad Ø (2009)
    Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients
    Acta Ophthalmol, 87 (8), 830-6
    DOI 10.1111/j.1755-3768.2008.01378.x, PubMed 19055657
  2. Gao Q, Geng L, Kvalheim G, Gaudernack G, Suo Z (2009)
    Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3
    Ultrastruct Pathol, 33 (4), 175-81
    DOI 10.1080/01913120903086072, PubMed 19728235
  3. Huang TS, Grodeland G, Sleire L, Wang MY, Kvalheim G, Laerum OD (2009)
    Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro
    Chronobiol Int, 26 (2), 242-57
    DOI 10.1080/07420520902766025, PubMed 19212839

Publications 2008

  1. Ikdahl T, Josefsen D, Jakobsen E, Delabie J, Fosså SD (2008)
    Concurrent mediastinal germ-cell tumour and haematological malignancy: case report and short review of literature
    Acta Oncol, 47 (3), 466-9
    DOI 10.1080/02841860701636272, PubMed 18348004
  2. Lazarova P, Kvalheim G, Gercheva L, Metodiev K (2008)
    Experimental attempt to produce mRNA transfected dendritic cells derived from enriched CD34+blood progenitor cells
    Cent. Eur. J. Med., 3 (1), 21-28
    DOI 10.2478/s11536-007-0072-9

Publications 2007

  1. Berg A, Berner A, Lilleby W, Bruland ØS, Fosså SD, Nesland JM, Kvalheim G (2007)
    Impact of disseminated tumor cells in bone marrow at diagnosis in patients with nonmetastatic prostate cancer treated by definitive radiotherapy
    Int J Cancer, 120 (8), 1603-9
    DOI 10.1002/ijc.22488, PubMed 17230512
  2. Jarnjak-Jankovic S, Hammerstad H, Saebøe-Larssen S, Kvalheim G, Gaudernack G (2007)
    A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines
    BMC Cancer, 7, 119
    DOI 10.1186/1471-2407-7-119, PubMed 17608923
  3. Jarnjak-Jankovic S, Saebøe-Larssen S, Kvalheim G, Gaudernack G (2007)
    mRNA transfection of DC in the immature or mature state: comparable in vitro priming of Th and cytotoxic T lymphocytes against DC electroporated with tumor cell line-derived mRNA
    Cytotherapy, 9 (6), 587-92
    DOI 10.1080/14653240701466354, PubMed 17882723
  4. Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Strømberg M, Wiedswang G, Kvalheim G, Kåresen R, Nesland JM, Børresen-Dale AL, Sørlie T (2007)
    Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
    Mol Oncol, 1 (2), 160-71
    DOI 10.1016/j.molonc.2007.03.004, PubMed 19383292
  5. Shanker A, Verdeil G, Buferne M, Inderberg-Suso EM, Puthier D, Joly F, Nguyen C, Leserman L, Auphan-Anezin N, Schmitt-Verhulst AM (2007)
    CD8 T cell help for innate antitumor immunity
    J Immunol, 179 (10), 6651-62
    DOI 10.4049/jimmunol.179.10.6651, PubMed 17982055
  6. Textoris-Taube K, Henklein P, Pollmann S, Bergann T, Weisshoff H, Seifert U, Drung I, Mügge C, Sijts A, Kloetzel PM, Kuckelkorn U (2007)
    The N-terminal flanking region of the TRP2360-368 melanoma antigen determines proteasome activator PA28 requirement for epitope liberation
    J Biol Chem, 282 (17), 12749-54
    DOI 10.1074/jbc.M611644200, PubMed 17308306
  7. Yu X, Bauer K, Wernhoff P, Ibrahim SM (2007)
    Using an advanced intercross line to identify quantitative trait loci controlling immune response during collagen-induced arthritis
    Genes Immun, 8 (4), 296-301
    DOI 10.1038/sj.gene.6364385, PubMed 17361202

Publications 2006

  1. Brunsvig PF, Aamdal S, Gjertsen MK, Kvalheim G, Markowski-Grimsrud CJ, Sve I, Dyrhaug M, Trachsel S, Møller M, Eriksen JA, Gaudernack G (2006)
    Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
    Cancer Immunol Immunother, 55 (12), 1553-64
    DOI 10.1007/s00262-006-0145-7, PubMed 16491401
  2. Davidson B, Konstantinovsky S, Kleinberg L, Nguyen MT, Bassarova A, Kvalheim G, Nesland JM, Reich R (2006)
    The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma
    Gynecol Oncol, 102 (3), 453-61
    DOI 10.1016/j.ygyno.2006.01.034, PubMed 16494928
  3. Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G (2006)
    Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
    Int J Cancer, 118 (11), 2877-81
    DOI 10.1002/ijc.21709, PubMed 16381016
  4. Gratama J, Kvalheim G, Orfao A (2006)
    Standardization of cell analysis methods in clinical cellular therapy programs: A challenge for ISCT
    Cytotherapy, 8 (6), 528-9
    DOI 10.1080/14653240601056354, PubMed 17148028
  5. Huijbers IJ, Krimpenfort P, Chomez P, van der Valk MA, Song JY, Inderberg-Suso EM, Schmitt-Verhulst AM, Berns A, Van den Eynde BJ (2006)
    An inducible mouse model of melanoma expressing a defined tumor antigen
    Cancer Res, 66 (6), 3278-86
    DOI 10.1158/0008-5472.CAN-05-3216, PubMed 16540681
  6. Kyte JA, Kvalheim G, Lislerud K, thor Straten P, Dueland S, Aamdal S, Gaudernack G (2006)
    T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
    Cancer Immunol Immunother, 56 (5), 659-75
    DOI 10.1007/s00262-006-0222-y, PubMed 16947019
  7. Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M, Gullestad HP, Ryder T, Lislerud K, Hammerstad H, Gaudernack G (2006)
    Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
    Cancer Gene Ther, 13 (10), 905-18
    DOI 10.1038/sj.cgt.7700961, PubMed 16710345
  8. Lazarova P, Wu Q, Kvalheim G, Suo Z, Haakenstad KW, Metodiev K, Nesland JM (2006)
    Growth factor receptors in hematopoietic stem cells: EPH family expression in CD34+ and CD133+ cell populations from mobilized peripheral blood
    Int J Immunopathol Pharmacol, 19 (1), 49-56
    PubMed 16569339
  9. Liljander M, Sällström MA, Andersson S, Wernhoff P, Andersson A, Holmdahl R, Mattsson R (2006)
    Identification of genetic regions of importance for reproductive performance in female mice
    Genetics, 173 (2), 901-9
    DOI 10.1534/genetics.105.054049, PubMed 16547111
  10. Wiedswang G, Borgen E, Schirmer C, Kåresen R, Kvalheim G, Nesland JM, Naume B (2006)
    Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer
    Int J Cancer, 118 (8), 2013-9
    DOI 10.1002/ijc.21576, PubMed 16287086
  11. Yu X, Bauer K, Wernhoff P, Koczan D, Möller S, Thiesen HJ, Ibrahim SM (2006)
    Fine mapping of collagen-induced arthritis quantitative trait loci in an advanced intercross line
    J Immunol, 177 (10), 7042-9
    DOI 10.4049/jimmunol.177.10.7042, PubMed 17082620

Publications 2005

  1. Elloul S, Elstrand MB, Nesland JM, Tropé CG, Kvalheim G, Goldberg I, Reich R, Davidson B (2005)
    Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
    Cancer, 103 (8), 1631-43
    DOI 10.1002/cncr.20946, PubMed 15742334
  2. Jarnjak-Jankovic S, Pettersen RD, Saebøe-Larssen S, Wesenberg F, Gaudernack G (2005)
    Evaluation of dendritic cells loaded with apoptotic cancer cells or expressing tumour mRNA as potential cancer vaccines against leukemia
    BMC Cancer, 5, 20
    DOI 10.1186/1471-2407-5-20, PubMed 15720715
  3. Jarnjak-Jankovic S, Pettersen RD, Saebøe-Larssen S, Wesenberg F, Olafsen MR, Gaudernack G (2005)
    Preclinical evaluation of autologous dendritic cells transfected with mRNA or loaded with apoptotic cells for immunotherapy of high-risk neuroblastoma
    Cancer Gene Ther, 12 (8), 699-707
    DOI 10.1038/sj.cgt.7700820, PubMed 15846368
  4. Johannesson M, Karlsson J, Wernhoff P, Nandakumar KS, Lindqvist AK, Olsson L, Cook AD, Andersson A, Holmdahl R (2005)
    Identification of epistasis through a partial advanced intercross reveals three arthritis loci within the Cia5 QTL in mice
    Genes Immun, 6 (3), 175-85
    DOI 10.1038/sj.gene.6364155, PubMed 15716976
  5. Josefsen D, Fosså S (2005)
    The management strategies for stage I seminoma
    Clin Oncol (R Coll Radiol), 17 (7), 539-42
    DOI 10.1016/j.clon.2005.07.002, PubMed 16238141
  6. Karlsen OA, Kindingstad L, Angelskår SM, Bruseth LJ, Straume D, Puntervoll P, Fjellbirkeland A, Lillehaug JR, Jensen HB (2005)
    Identification of a copper-repressible C-type heme protein of Methylococcus capsulatus (Bath). A member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins
    FEBS J, 272 (24), 6324-35
    DOI 10.1111/j.1742-4658.2005.05020.x, PubMed 16336269
  7. Karlsson J, Johannesson M, Lindvall T, Wernhoff P, Holmdahl R, Andersson A (2005)
    Genetic interactions in Eae2 control collagen-induced arthritis and the CD4+/CD8+ T cell ratio
    J Immunol, 174 (1), 533-41
    DOI 10.4049/jimmunol.174.1.533, PubMed 15611280
  8. Konstantinovsky S, Nielsen S, Vyberg M, Kvalheim G, Nesland JM, Reich R, Davidson B (2005)
    Angiogenic molecule expression is downregulated in effusions from breast cancer patients
    Breast Cancer Res Treat, 94 (1), 71-80
    DOI 10.1007/s10549-005-7328-3, PubMed 16142438
  9. Kvalheim G (2005)
    Stem cell therapy still not here
    Cytotherapy, 7 (5), 456-7
    DOI 10.1080/14653240500319267, PubMed 16236635
  10. Kyte JA, Kvalheim G, Aamdal S, Saebøe-Larssen S, Gaudernack G (2005)
    Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
    Cancer Gene Ther, 12 (6), 579-91
    DOI 10.1038/sj.cgt.7700837, PubMed 15818380
  11. Mazón Peláez I, Vogler S, Strauss U, Wernhoff P, Pahnke J, Brockmann G, Moch H, Thiesen HJ, Rolfs A, Ibrahim SM (2005)
    Identification of quantitative trait loci controlling cortical motor evoked potentials in experimental autoimmune encephalomyelitis: correlation with incidence, onset and severity of disease
    Hum Mol Genet, 14 (14), 1977-89
    DOI 10.1093/hmg/ddi203, PubMed 15917267
  12. Mu LJ, Kyte JA, Kvalheim G, Aamdal S, Dueland S, Hauser M, Hammerstad H, Waehre H, Raabe N, Gaudernack G (2005)
    Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
    Br J Cancer, 93 (7), 749-56
    DOI 10.1038/sj.bjc.6602761, PubMed 16136047

Publications 2004

  1. Abrahamsen JF, Rusten L, Bakken AM, Bruserud Ø (2004)
    Better preservation of early hematopoietic progenitor cells when human peripheral blood progenitor cells are cryopreserved with 5 percent dimethylsulfoxide instead of 10 percent dimethylsulfoxide
    Transfusion, 44 (5), 785-9
    DOI 10.1111/j.1537-2995.2004.03336.x, PubMed 15104663
  2. Bauer K, Yu X, Wernhoff P, Koczan D, Thiesen HJ, Ibrahim SM (2004)
    Identification of new quantitative trait loci in mice with collagen-induced arthritis
    Arthritis Rheum, 50 (11), 3721-8
    DOI 10.1002/art.20624, PubMed 15529344
  3. Blystad AK, Delabie J, Kvaløy S, Holte H, Vålerhaugen H, Ikonomou I, Kvalheim G (2004)
    Infused CD34 cell dose, but not tumour cell content of peripheral blood progenitor cell grafts, predicts clinical outcome in patients with diffuse large B-cell lymphoma and follicular lymphoma grade 3 treated with high-dose therapy
    Br J Haematol, 125 (5), 605-12
    DOI 10.1111/j.1365-2141.2004.04951.x, PubMed 15147376
  4. Gunnlaugsdottir B, Maggadottir SM, Ludviksson BR (2004)
    Anti-CD28-induced co-stimulation and TCR avidity regulates the differential effect of TGF-beta1 on CD4+ and CD8+ naïve human T-cells
    Int Immunol, 17 (1), 35-44
    DOI 10.1093/intimm/dxh183, PubMed 15557315
  5. Lazarova P, Lijun M, Hammerstad H, Nesland J, Gaudernack G, Kvalheim G (2004)
    Experimental attempt to introduce a vaccine therapy by using DC-developed from CD34+cells
    NATO SCI SER I LIFE, 361, 134
  6. Mu LJ, Lazarova P, Gaudernack G, Saeboe-Larssen S, Kvalheim G (2004)
    Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34(+) blood progenitor cells
    Int J Immunopathol Pharmacol, 17 (3), 255-63
    DOI 10.1177/039463200401700305, PubMed 15461859
  7. Naume B, Wiedswang G, Borgen E, Kvalheim G, Kåresen R, Qvist H, Janbu J, Harbitz T, Nesland JM (2004)
    The prognostic value of isolated tumor cells in bone marrow in breast cancer patients: evaluation of morphological categories and the number of clinically significant cells
    Clin Cancer Res, 10 (9), 3091-7
    DOI 10.1158/1078-0432.ccr-03-0373, PubMed 15131048
  8. Østby I, Kvalheim G, Rusten LS, Grøttum P (2004)
    Mathematical modeling of granulocyte reconstitution after high-dose chemotherapy with stem cell support: effect of post-transplant G-CSF treatment
    J Theor Biol, 231 (1), 69-83
    DOI 10.1016/j.jtbi.2004.05.010, PubMed 15363930
  9. Smeland S, Blystad AK, Kvaløy SO, Ikonomou IM, Delabie J, Kvalheim G, Hammerstrøm J, Lauritzsen GF, Holte H (2004)
    Treatment of Burkitt's/Burkitt-like lymphoma in adolescents and adults: a 20-year experience from the Norwegian Radium Hospital with the use of three successive regimens
    Ann Oncol, 15 (7), 1072-8
    DOI 10.1093/annonc/mdh262, PubMed 15205201
  10. Wiedswang G, Borgen E, Kåresen R, Qvist H, Janbu J, Kvalheim G, Nesland JM, Naume B (2004)
    Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavorable clinical outcome
    Clin Cancer Res, 10 (16), 5342-8
    DOI 10.1158/1078-0432.CCR-04-0245, PubMed 15328170

Publications 2003

  1. Kvalheim G, Gratwohl A, Urbano-Ispizua A, JACIE national representatives (2003)
    JACIE accreditation in Europe moves ahead
    Cytotherapy, 5 (4), 306-8
    DOI 10.1080/14653240310002216, PubMed 12944236
  2. Lilleby W, Nesland JM, Fosså SD, Torlakovic G, Waehre H, Kvalheim G (2003)
    The prognostic impact of cytokeratin-positive cells in bone marrow of patients with localized prostate cancer
    Int J Cancer, 103 (1), 91-6
    DOI 10.1002/ijc.10780, PubMed 12455058
  3. Mu LJ, Gaudernack G, Saebøe-Larssen S, Hammerstad H, Tierens A, Kvalheim G (2003)
    A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines
    Scand J Immunol, 58 (5), 578-86
    DOI 10.1046/j.1365-3083.2003.01333.x, PubMed 14629630
  4. Noble A, Leggat JA, Inderberg EM (2003)
    CD8+ immunoregulatory cells in the graft-versus-host reaction: CD8 T cells activate dendritic cells to secrete interleukin-12/interleukin-18 and induce T helper 1 autoantibody
    Immunology, 109 (4), 476-86
    DOI 10.1046/j.1365-2567.2003.01687.x, PubMed 12871213
  5. Ogreid P, Kvalheim G (2003)
    Old and new research into micrometastases in prostate cancer
    Scand J Urol Nephrol Suppl (212), 37-9
    PubMed 12841326
  6. Ogreid P, Kvalheim G (2003)
    Old and new research into micrometastases in prostate cancer
    Scand. J. Urol. Nephrol., 37 212, 37-39
    DOI 10.1080/03008880310006931
  7. Olofsson P, Lu S, Holmberg J, Song T, Wernhoff P, Pettersson U, Holmdahl R (2003)
    A comparative genetic analysis between collagen-induced arthritis and pristane-induced arthritis
    Arthritis Rheum, 48 (8), 2332-42
    DOI 10.1002/art.11100, PubMed 12905489
  8. Olofsson P, Wernhoff P, Holmberg J, Holmdahl R (2003)
    Two-loci interaction confirms arthritis-regulating quantitative trait locus on rat chromosome 6
    Genomics, 82 (6), 652-9
    DOI 10.1016/s0888-7543(03)00208-8, PubMed 14611807
  9. Østby I, Rusten LS, Kvalheim G, Grøttum P (2003)
    A mathematical model for reconstitution of granulopoiesis after high dose chemotherapy with autologous stem cell transplantation
    J Math Biol, 47 (2), 101-36
    DOI 10.1007/s00285-003-0198-6, PubMed 12883857
  10. Paus E, Almåsbak H, Børmer OP, Warren DJ (2003)
    A single-chain-Fv-based immunofluorometric assay specific for the CEA variant NCA-2
    J Immunol Methods, 283 (1-2), 125-39
    DOI 10.1016/j.jim.2003.08.018, PubMed 14659905
  11. Rinaldo CH, Myhre MR, Alstad H, Nilssen Ø, Traavik T (2003)
    Human polyomavirus BK (BKV) transiently transforms and persistently infects cultured osteosarcoma cells
    Virus Res, 93 (2), 181-7
    DOI 10.1016/s0168-1702(03)00096-0, PubMed 12782366
  12. Schouten HC, Qian W, Kvaloy S, Porcellini A, Hagberg H, Johnsen HE, Doorduijn JK, Sydes MR, Kvalheim G (2003)
    High-dose therapy improves progression-free survival and survival in relapsed follicular non-Hodgkin's lymphoma: results from the randomized European CUP trial
    J Clin Oncol, 21 (21), 3918-27
    DOI 10.1200/JCO.2003.10.023, PubMed 14517188
  13. Taraldsrud E, Aandahl GS, Stavem K, Kvalheim G, Jørstad S (2003)
    [Therapeutic hemapheresis]
    Tidsskr Nor Laegeforen, 123 (17), 2439-42
    PubMed 14594145
  14. Taraldsrud E, Kvalheim G, Jørstad S, Stavem K, Aandahl GS (2003)
    A survey of therapeutic hemapheresis in Norway year 2000
    Transfus Apher Sci, 28 (2), 135-41
    DOI 10.1016/S1473-0502(03)00004-1, PubMed 12679117
  15. Wiedswang G, Borgen E, Kåresen R, Kvalheim G, Nesland JM, Qvist H, Schlichting E, Sauer T, Janbu J, Harbitz T, Naume B (2003)
    Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer
    J Clin Oncol, 21 (18), 3469-78
    DOI 10.1200/JCO.2003.02.009, PubMed 12972522

Publications 2002

  1. Gjertsen MK, Saeterdal I, Saebøe-Larssen S, Gaudernack G (2002)
    HLA-A3 restricted mutant ras specific cytotoxic T-lymphocytes induced by vaccination with T-helper epitopes
    J Mol Med (Berl), 81 (1), 43-50
    DOI 10.1007/s00109-002-0390-y, PubMed 12545248
  2. Lundqvist A, Noffz G, Pavlenko M, Saebøe-Larssen S, Fong T, Maitland N, Pisa P (2002)
    Nonviral and viral gene transfer into different subsets of human dendritic cells yield comparable efficiency of transfection
    J Immunother, 25 (6), 445-54
    DOI 10.1097/00002371-200211000-00001, PubMed 12439342

Publications 2001

  1. Aurlien E, Holte H, Kvaloy S, Jakobsen E, Rusten LS, Kvalheim G (2001)
    Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
    Eur. J. Haematol., 66 64, 14-20
  2. Aurlien E, Holte H, Kvaløy S, Jakobsen E, Rusten LS, Kvalheim G (2001)
    Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
    Eur J Haematol Suppl, 64, 14-20
    PubMed 11486395
  3. Blystad AK, Enblad G, Kvaløy S, Berglund A, Delabie J, Holte H, Carlson K, Kvalheim G, Bengtsson M, Hagberg H (2001)
    High-dose therapy with autologous stem cell transplantation in patients with peripheral T cell lymphomas
    Bone Marrow Transplant, 27 (7), 711-6
    DOI 10.1038/sj.bmt.1702867, PubMed 11360110
  4. Blystad AK, Holte H, Kvaløy S, Smeland E, Delabie J, Kvalheim G (2001)
    High-dose therapy in patients with Hodgkin's disease: the use of selected CD34(+) cells is as safe as unmanipulated peripheral blood progenitor cells
    Bone Marrow Transplant, 28 (9), 849-57
    DOI 10.1038/sj.bmt.1703244, PubMed 11781645
  5. Blystad AK, Torlakovic E, Holte H, Kvaløy S, Lenschow E, Kvalheim G (2001)
    CD34(+) cell enrichment depletes atypical CD30(+) cells from PBPC grafts in patients with HD
    Cytotherapy, 3 (4), 295-305
    DOI 10.1080/146532401317070934, PubMed 12171718
  6. Hall KS, Wiklund T, Erikstein B, Holte H, Kvalheim G, Sommer HH, Andersen A, Skovlund E, Bergh J, Hall C (2001)
    Effects of dose-intensive chemotherapy and radiotherapy on serum n-terminal proatrial natriuretic peptide in high-risk breast cancer patients
    Breast Cancer Res Treat, 67 (3), 235-44
    DOI 10.1023/a:1017946315032, PubMed 11561769
  7. Kraetsch HG, Unger C, Wernhoff P, Schneider C, Kalden JR, Holmdahl R, Burkhardt H (2001)
    Cartilage-specific autoimmunity in rheumatoid arthritis: characterization of a triple helical B cell epitope in the integrin-binding-domain of collagen type II
    Eur J Immunol, 31 (6), 1666-73
    DOI 10.1002/1521-4141(200106)31:6<1666::aid-immu1666>;2-t, PubMed 11385610
  8. Kvalheim G, Urbano-Ispizua A, Gratwohl A (2001)
    Regulatory aspects and accreditation of the clinical use of hematopoietic progenitor cells in Europe
    J Biol Regul Homeost Agents, 15 (1), 79-80
    PubMed 11388748
  9. Naume B, Borgen E, Kvalheim G, Kåresen R, Qvist H, Sauer T, Kumar T, Nesland JM (2001)
    Detection of isolated tumor cells in bone marrow in early-stage breast carcinoma patients: comparison with preoperative clinical parameters and primary tumor characteristics
    Clin Cancer Res, 7 (12), 4122-9
    PubMed 11751511
  10. Saeterdal I, Bjørheim J, Lislerud K, Gjertsen MK, Bukholm IK, Olsen OC, Nesland JM, Eriksen JA, Møller M, Lindblom A, Gaudernack G (2001)
    Frameshift-mutation-derived peptides as tumor-specific antigens in inherited and spontaneous colorectal cancer
    Proc Natl Acad Sci U S A, 98 (23), 13255-60
    DOI 10.1073/pnas.231326898, PubMed 11687624
  11. Yang HT, Bergsteinsdottir K, Wernhoff P, Linington C, Pettersson U, Holmdahl R (2001)
    Genetic linkage analysis of the antibody responses to myelin basic protein and myelin oligodendrocyte glycoprotein in rats immunized with rat spinal cord homogenate
    J Neuroimmunol, 117 (1-2), 21-9
    DOI 10.1016/s0165-5728(01)00320-4, PubMed 11431001

Publications 2000

  1. Aurlien E, Larsen RH, Kvalheim G, Bruland OS (2000)
    Demonstration of highly specific toxicity of the alpha-emitting radioimmunoconjugate(211)At-rituximab against non-Hodgkin's lymphoma cells
    Br J Cancer, 83 (10), 1375-9
    DOI 10.1054/bjoc.2000.1453, PubMed 11044364
  2. Myklebust JH, Smeland EB, Josefsen D, Sioud M (2000)
    Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
    Blood, 95 (2), 510-8
    DOI 10.1182/blood.V95.2.510, PubMed 10627456
  3. Simonsen GS, Myhre MR, Dahl KH, Olsvik O, Sundsfjord A (2000)
    Typeability of Tn1546-like elements in vancomycin-resistant enterococci using long-range PCRs and specific analysis of polymorphic regions
    Microb Drug Resist, 6 (1), 49-57
    DOI 10.1089/mdr.2000.6.49, PubMed 10868807

Publications 1999

  1. Blystad A, Kvalheim G, Torlakovic E, Holte H, Jacobsen E, Beiske K, Vâlerhaugen H, Lenschow E, Kvaloy S (1999)
    High-dose therapy supported with immunomagnetic purged autologous bone marrow in high-grade B cell non-Hodgkin's lymphoma
    Bone Marrow Transplant, 24 (8), 865-72
    DOI 10.1038/sj.bmt.1701990, PubMed 10516698
  2. Borgen E, Naume B, Nesland JM, Kvalheim G, Beiske K, Fodstad O, Diel I, Solomayer EF, Theocharous P, Coombes RC, Smith BM, Wunder E, Marolleau JP, Garcia J, Pantel K (1999)
    Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells
    Cytotherapy, 1 (5), 377-88
    DOI 10.1080/0032472031000141283, PubMed 20426539
  3. Crown J, Coiffier B, Cortés-Funes H, Guillaume T, Kanz L, Kvalheim G, Marty M, Symann M (1999)
    ESTIC position paper: high-dose chemotherapy for breast cancer, investigation should continue
    Ann Oncol, 10 (8), 903-5
    DOI 10.1023/a:1008396811371, PubMed 10509150
  4. Davidson B, Risberg B, Kristensen G, Kvalheim G, Emilsen E, Bjåmer A, Berner A (1999)
    Detection of cancer cells in effusions from patients diagnosed with gynaecological malignancies. Evaluation of five epithelial markers
    Virchows Arch, 435 (1), 43-9
    DOI 10.1007/s004280050393, PubMed 10431845
  5. Kvalheim G, Berli M (1999)
    EBMT and ISHAGE-Europe create a foundation for inspection and accreditation in Europe
    Cytotherapy, 1 (5), 363-4
    DOI 10.1080/0032472031000141280, PubMed 20426536
  6. Kvalheim G, Naume B, Nesland JM (1999)
    Minimal residual disease in breast cancer
    Cancer Metastasis Rev, 18 (1), 101-8
    DOI 10.1023/a:1006216504892, PubMed 10505549
  7. Lindman H, Wiklund T, Holte H, Ljungman P, Blomqvist C, Kvalheim G, Bengtsson M, Höglund M, Wilking N, Bergh J (1999)
    FEC mobilized stem cells for high-dose therapy in breast cancer patients. SB6 9401 Study Group
    Acta Oncol, 38 (2), 239-45
    DOI 10.1080/028418699431672, PubMed 10227447
  8. Myklebust JH, Josefsen D, Blomhoff HK, Levy FO, Naderi S, Reed JC, Smeland EB (1999)
    Activation of the cAMP signaling pathway increases apoptosis in human B-precursor cells and is associated with downregulation of Mcl-1 expression
    J Cell Physiol, 180 (1), 71-80
    DOI 10.1002/(SICI)1097-4652(199907)180:1<71::AID-JCP8>3.0.CO;2-N, PubMed 10362019
  9. Nordøy T, Kolstad A, Endresen P, Holte H, Kvaløy S, Kvalheim G, Husebekk A (1999)
    Persistent changes in the immune system 4-10 years after ABMT
    Bone Marrow Transplant, 24 (8), 873-8
    DOI 10.1038/sj.bmt.1702006, PubMed 10516699
  10. Serke S, Johnsen H, Huhn D, Kvalheim G (1999)
    European survey of the flow cytometric determination of CD34-expressing cells
    Cytotherapy, 1 (4), 343-7
    DOI 10.1080/0032472031000141275, PubMed 20426564

Publications 1998

  1. Aurlien E, Holte H, Pharo A, Kvaløy S, Jakobsen E, Smeland EB, Kvalheim G (1998)
    Combination chemotherapy with mitoguazon, ifosfamide, MTX, etoposide (MIME) and G-CSF can efficiently mobilize PBPC in patients with Hodgkin's and non-Hodgkin's lymphoma
    Bone Marrow Transplant, 21 (9), 873-8
    DOI 10.1038/sj.bmt.1701192, PubMed 9613778
  2. Borgen E, Beiske K, Trachsel S, Nesland JM, Kvalheim G, Herstad TK, Schlichting E, Qvist H, Naume B (1998)
    Immunocytochemical detection of isolated epithelial cells in bone marrow: non-specific staining and contribution by plasma cells directly reactive to alkaline phosphatase
    J Pathol, 185 (4), 427-34
    DOI 10.1002/(SICI)1096-9896(199808)185:4<427::AID-PATH127>3.0.CO;2-7, PubMed 9828843
  3. Kvalheim G (1998)
    Diagnosis of minimal residual disease in bone marrow and blood in cancer patients--methods and clinical implications
    Acta Oncol, 37 (5), 455-62
    DOI 10.1080/028418698430403, PubMed 9831374
  4. Kvalheim G (1998)
    Detection and quantification of residual disease in bone marrow and PBPC
    EUROCANCER 98, 19-21
  5. Naume B, Borgen E, Nesland JM, Beiske K, Gilen E, Renolen A, Ravnås G, Qvist H, Kåresen R, Kvalheim G (1998)
    Increased sensitivity for detection of micrometastases in bone-marrow/peripheral-blood stem-cell products from breast-cancer patients by negative immunomagnetic separation
    Int J Cancer, 78 (5), 556-60
    DOI 10.1002/(sici)1097-0215(19981123)78:5<556::aid-ijc5>;2-g, PubMed 9808522
  6. Oftung F, Borka E, Kvalheim G, Mustafa AS (1998)
    Mycobacterial crossreactivity of M. tuberculosis reactive T cell clones from naturally converted PPD positive healthy subjects
    FEMS Immunol Med Microbiol, 20 (3), 231-8
    DOI 10.1111/j.1574-695X.1998.tb01131.x, PubMed 9566494

Publications 1997

  1. Naume B, Borgen E, Beiske K, Herstad TK, Ravnås G, Renolen A, Trachsel S, Thrane-Steen K, Funderud S, Kvalheim G (1997)
    Immunomagnetic techniques for the enrichment and detection of isolated breast carcinoma cells in bone marrow and peripheral blood
    J Hematother, 6 (2), 103-14
    DOI 10.1089/scd.1.1997.6.103, PubMed 9131439

Publications 1996

  1. Atta J, Martin H, Bruecher J, Elsner S, Wassmann B, Rode C, Russ A, Kvalheim G, Hoelzer D (1996)
    Residual leukemia and immunomagnetic bead purging in patients with BCR-ABL-positive acute lymphoblastic leukemia
    Bone Marrow Transplant, 18 (3), 541-8
    PubMed 8879615
  2. Kolstad A, Holte H, Kvaløy S, Jakobsen E, Erikstein B, Aurlien E, Kvalheim G, Bøhler PJ, Langholm R (1996)
    [High-dose therapy with autologous stem cell support in malignant lymphoma and breast cancer. Experiences with hematopoietic stem cells isolate from blood]
    Tidsskr Nor Laegeforen, 116 (21), 2547-51
    PubMed 8928122
  3. Kongsgaard UE, Wang MY, Kvalheim G (1996)
    Leucocyte depletion filter removes cancer cells in human blood
    Acta Anaesthesiol Scand, 40 (1), 118-20
    DOI 10.1111/j.1399-6576.1996.tb04397.x, PubMed 8904269
  4. Kvalheim G (1996)
    Purging of autografts: methods and clinical significance
    Ann Med, 28 (2), 167-73
    DOI 10.3109/07853899609092942, PubMed 8732646
  5. Kvalheim G (1996)
    Detection of occult tumour cells in bone marrow and blood in breast cancer patients--methods and clinical significance
    Acta Oncol, 35 Suppl 8, 13-8
    DOI 10.3109/02841869609098516, PubMed 9073044
  6. Kvalheim G, Holte H, Jakobsen E, Kvaloy S (1996)
    Immunomagnetic purging of lymphoma cells from autografts
    J Hematother, 5 (5), 561-2
    DOI 10.1089/scd.1.1996.5.561, PubMed 8938530
  7. Kvalheim G, Wang MY, Pharo A, Holte H, Jacobsen E, Beiske K, Kvaløy S, Smeland E, Funderud S, Fodstad O (1996)
    Purging of tumor cells from leukapheresis products: experimental and clinical aspects
    J Hematother, 5 (4), 427-36
    DOI 10.1089/scd.1.1996.5.427, PubMed 8877718

Publications 1995

  1. Deggerdal AH, Pettersen F, Kvalheim G, Hornes E, Smeland E, Fodstad O, Hovig E (1995)
    Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
    Lab Invest, 72 (4), 411-8
    PubMed 7723279
  2. Josefsen D, Waehre H, Paus E, Fosså SD (1995)
    Increase of serum prostatic specific antigen and clinical progression in pN + MO prostate cancer
    Br J Urol, 75 (4), 502-6
    DOI 10.1111/j.1464-410x.1995.tb07273.x, PubMed 7540482
  3. Lundblad R, Wang MY, Kvalheim G, Lingaas E, Giercksky KE (1995)
    Granulocyte colony-stimulating factor improves myelopoiesis and host defense in fulminant intra-abdominal sepsis in rats
    Shock, 4 (1), 68-73
    DOI 10.1097/00024382-199507000-00011, PubMed 7552781
  4. Stacy RA, Espelund M, Saebøe-Larssen S, Hollung K, Helliesen E, Jakobsen KS (1995)
    Evolution of the Group 1 late embryogenesis abundant (Lea) genes: analysis of the Lea B19 gene family in barley
    Plant Mol Biol, 28 (6), 1039-54
    DOI 10.1007/BF00032665, PubMed 7548822
  5. Wang MY, Fodstad O, Ludwig WD, Bengtsson M, Totterman T, Funderub S, Martin H, Kvalheim G (1995)
    An Effective, Direct Immunomagnetic Procedure for Purging Acute Lymphoblastic Leukemia Cells from Human Bone Marrow
    Pathol Oncol Res, 1 (1), 32-37
    DOI 10.1007/BF02893581, PubMed 11173565

Publications 1994

  1. Andersson S, Saebøe-Larssen S, Lambertsson A, Merriam J, Jacobs-Lorena M (1994)
    A Drosophila third chromosome Minute locus encodes a ribosomal protein
    Genetics, 137 (2), 513-20
    DOI 10.1093/genetics/137.2.513, PubMed 8070662
  2. Kavløy S, Holte H, Kvalheim G (1994)
    [High-dose autologous stem cell support in malignant diseases--an established method, uncertain indication]
    Tidsskr Nor Laegeforen, 114 (19), 2240-1
    PubMed 7992286
  3. Kvalheim G, Jakobsen E, Holte H, Beiske K, Langholm R, Høiby A, Wang MY, Funderund S, Fodstad O, Smeland E (1994)
    Autologous bone marrow transplantation of non-Hodgkin's lymphoma patients with marrow purged using immunomagnetic beads
    Prog Clin Biol Res, 389, 133-8
    PubMed 7700895
    J. Chromatogr. A, 669 (1-2), 185-193
    DOI 10.1016/0021-9673(94)80347-1
  5. Smeland EB, Rusten L, Jacobsen SE, Skrede B, Blomhoff R, Wang MY, Funderud S, Kvalheim G, Blomhoff HK (1994)
    All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells
    Blood, 84 (9), 2940-5
    DOI 10.1182/blood.V84.9.2940.bloodjournal8492940, PubMed 7524761
  6. Wang MY, Fodstad O, Funderud S, Bengtsson M, Totterman T, Ludwig WD, Martin H, Kvalheim G (1994)
    A direct and effective immunomagnetic method for bone marrow purging in non-T ALL malignancies. The use of an anti-HLA-DR antibody gives sustained engraftment
    Prog Clin Biol Res, 389, 119-24
    PubMed 7700893

Publications 1993

  1. Fiskerstrand T, Refsum H, Kvalheim G, Ueland PM (1993)
    Homocysteine and other thiols in plasma and urine: automated determination and sample stability
    Clin Chem, 39 (2), 263-71
    PubMed 8432015
  2. Josefsen D, Ous S, Høie J, Stenwig AE, Fosså SD (1993)
    Salvage treatment in male patients with germ cell tumours
    Br J Cancer, 67 (3), 568-72
    DOI 10.1038/bjc.1993.104, PubMed 8382512

Publications 1992

  1. Espelund M, Saebøe-Larssen S, Hughes DW, Galau GA, Larsen F, Jakobsen KS (1992)
    Late embryogenesis-abundant genes encoding proteins with different numbers of hydrophilic repeats are regulated differentially by abscisic acid and osmotic stress
    Plant J, 2 (2), 241-52
    PubMed 1302052
  2. Odegaard OR, Lindahl AK, Try K, Kvalheim G, Sørbø JH (1992)
    Recurrent venous thrombosis during warfarin treatment related to acquired protein S deficiency
    Thromb Res, 66 (6), 729-34
    DOI 10.1016/0049-3848(92)90048-f, PubMed 1519231
  3. Ogniben E, Hohaus S, Kvalheim G, Dörken B, Haas R (1992)
    Successful autologous transplantation of immunomagnetic bead purged bone marrow in non-Hodgkin's lymphoma
    Prog Clin Biol Res, 377, 189-95
    PubMed 1438415
  4. Rusten L, Kvaløy SO, Jakobsen E, Kvalheim G, Abrahamsen AF, Høiby EA, Sandven P, Lassen J, Bruu AL (1992)
    [Infection problems in the leukopenia phase after autologous bone marrow transplantation]
    Tidsskr Nor Laegeforen, 112 (13), 1723-6
    PubMed 1509434
    INT J CELL CLONING, 10 1, 108-110
    DOI 10.1002/stem.5530100735
  6. Smeland EB, Funderud S, Kvalheim G, Gaudernack G, Rasmussen AM, Rusten L, Wang MY, Tindle RW, Blomhoff HK, Egeland T (1992)
    Isolation and characterization of human hematopoietic progenitor cells: an effective method for positive selection of CD34+ cells
    Leukemia, 6 (8), 845-52
    PubMed 1379314
  7. Straka C, Kröner C, Dörken B, Kvalheim G (1992)
    Polymerase chain reaction monitoring shows a high efficacy of clinical immunomagnetic purging in patients with centroblastic-centrocytic non-Hodgkin's lymphoma
    Blood, 80 (10), 2688-90
    PubMed 1421385
  8. Wang MY, Kvalheim G, Kvaløy S, Beiske K, Jakobsen E, Wijdenes J, Pihl A, Fodstad O (1992)
    An effective immunomagnetic method for bone marrow purging in T cell malignancies
    Bone Marrow Transplant, 9 (5), 319-23
    PubMed 1617315

Publications 1991

  1. Körbling M, Knauf W, Funderud S, Kvalheim G, Hunstein W (1991)
    Autologous transplantation of an immunomagnetic bead purged marrow in patients with relapsed acute lymphoblastic leukemia
    Haematologica, 76 Suppl 1, 29-36
    PubMed 1650742

Publications 1990

  1. Storm-Mathisen I, Glomstein A, Lie SO, Albrechtsen D, Monclair T, Kvalheim G, Jacobsen AB (1990)
    [Autologous bone marrow transplantation in children--experience with neuroblastoma]
    Tidsskr Nor Laegeforen, 110 (19), 2513-6
    PubMed 2219008

Publications 1988

  1. Fodstad O, Kvalheim G, Pihl A, Godal A, Funderud S (1988)
    New indirect approach to the therapeutic use of immunotoxins
    J Natl Cancer Inst, 80 (6), 439-43
    DOI 10.1093/jnci/80.6.439, PubMed 3259265
    Bone Marrow Transplant., 3 1, 97
  3. Oftung F, Mustafa AS, Shinnick TM, Houghten RA, Kvalheim G, Degre M, Lundin KE, Godal T (1988)
    Epitopes of the Mycobacterium tuberculosis 65-kilodalton protein antigen as recognized by human T cells
    J Immunol, 141 (8), 2749-54
    PubMed 2459228
  4. Tretli S, Kvalheim G, Thoresen S, Høst H (1988)
    Survival of breast cancer patients diagnosed during pregnancy or lactation
    Br J Cancer, 58 (3), 382-4
    DOI 10.1038/bjc.1988.224, PubMed 3179191
    MAKROMOL CHEM-M SYMP, 17, 177-211
    DOI 10.1002/masy.19880170113

Publications 1987

    Bone Marrow Transplant., 2 2, 99-103
  2. Kiesel S, Haas R, Moldenhauer G, Kvalheim G, Pezzutto A, Dörken B (1987)
    Removal of cells from a malignant B-cell line from bone marrow with immunomagnetic beads and with complement and immunoglobulin switch variant mediated cytolysis
    Leuk Res, 11 (12), 1119-25
    DOI 10.1016/0145-2126(87)90166-4, PubMed 3320581
  3. Kvalheim G, Fodstad O, Pihl A, Nustad K, Pharo A, Ugelstad J, Funderud S (1987)
    Elimination of B-lymphoma cells from human bone marrow: model experiments using monodisperse magnetic particles coated with primary monoclonal antibodies
    Cancer Res, 47 (3), 846-51
    PubMed 3492268
    Bone Marrow Transplant., 2 2, 81-83
    Bone Marrow Transplant., 2 2, 94-98
  6. Vartdal F, Kvalheim G, Lea TE, Bosnes V, Gaudernack G, Ugelstad J, Albrechtsen D (1987)
    Depletion of T lymphocytes from human bone marrow. Use of magnetic monosized polymer microspheres coated with T-lymphocyte-specific monoclonal antibodies
    Transplantation, 43 (3), 366-71
    DOI 10.1097/00007890-198703000-00010, PubMed 3103274

Publications 1986

  1. Mustafa AS, Kvalheim G, Degre M, Godal T (1986)
    Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: antigen specificity and lymphokine production
    Infect Immun, 53 (3), 491-7
    DOI 10.1128/iai.53.3.491-497.1986, PubMed 2427449

Publications 1985

  1. Kvalheim G, Gundersen S, Hager B, Fodstad O (1985)
    Intra-arterial infusion of mitomycin C in treatment of breast cancer: occurrence of skin necrosis in irradiated patients
    Radiother Oncol, 4 (2), 127-32
    DOI 10.1016/s0167-8140(85)80099-2, PubMed 3934716
  2. Ueland PM, Kvalheim G, Lønning PE, Kvinnsland S (1985)
    Determination of warfarin in human plasma by high performance liquid chromatography and photodiode array detector
    Ther Drug Monit, 7 (3), 329-35
    DOI 10.1097/00007691-198507030-00018, PubMed 4049474

Publications 1984

  1. Fodstad O, Kvalheim G, Godal A, Lotsberg J, Aamdal S, Høst H, Pihl A (1984)
    Phase I study of the plant protein ricin
    Cancer Res, 44 (2), 862-5
    PubMed 6692385

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