Publications 2024

Casey NP, Kleinmanns K, Forcados C, Gelebart PF, Joaquina S, Lode M, Benard E, Kaveh F, Caulier B, Helgestad Gjerde C, García de Jalón E, Warren DJ, Lindemann K, Rokkones E, Davidson B, Myhre MR, Kvalheim G, Bjørge L, McCormack E, Inderberg EM, Wälchli S (2024)
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
J Immunother Cancer, 12 (4)
DOI 10.1136/jitc-2023-008179, PubMed 38604812

Maggadottir SM, Dueland S, Mensali N, Hamre H, Andresen PA, Myhre MR, Juul HV, Bigalke I, Lundby M, Hønnåshagen TK, Sæbøe-Larssen S, Josefsen D, Hagtvedt T, Wälchli S, Kvalheim G, Inderberg EM (2024)
Transient TCR-based T-cell therapy in a patient with advanced treatment-resistant MSI-high colorectal cancer
Mol Ther (in press)
DOI 10.1016/j.ymthe.2024.04.009, PubMed 38582964

Publications 2023

Fløisand Y, Remberger M, Bigalke I, Josefsen D, Vålerhaugen H, Inderberg EM, Olaussen RW, Gjertsen BT, Goedkoop R, Geiger C, Prinz PU, Schnorfeil FM, Pinkernell K, Schendel DJ, Kvalheim G (2023)
WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy
Leukemia, 37 (9), 1842-1849
DOI 10.1038/s41375-023-01980-3, PubMed 37507426

Mensali N, Köksal H, Joaquina S, Wernhoff P, Casey NP, Romecin P, Panisello C, Rodriguez R, Vimeux L, Juzeniene A, Myhre MR, Fåne A, Ramírez CC, Maggadottir SM, Duru AD, Georgoudaki AM, Grad I, Maturana AD, Gaudernack G, Kvalheim G, Carcaboso AM, de Alava E, Donnadieu E, Bruland ØS, Menendez P et al. (2023)
ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma
Nat Commun, 14 (1), 3375
DOI 10.1038/s41467-023-39097-x, PubMed 37291203

Thomsen LCV, Honoré A, Reisæter LAR, Almås B, Børretzen A, Helle SI, Førde K, Kristoffersen EK, Kaada SH, Melve GK, Haslerud TM, Biermann M, Bigalke I, Kvalheim G, Azeem W, Olsen JR, Gabriel B, Knappskog S, Halvorsen OJ, Akslen LA, Bahn D, Pantel K, Riethdorf S, Ragde H, Gjertsen BT et al. (2023)
A phase I prospective, non-randomized trial of autologous dendritic cell-based cryoimmunotherapy in patients with metastatic castration-resistant prostate cancer
Cancer Immunol Immunother, 72 (7), 2357-2373
DOI 10.1007/s00262-023-03421-7, PubMed 36939854

Publications 2022

Maggadóttir SM, Kvalheim G, Wernhoff P, Sæbøe-Larssen S, Revheim ME, Josefsen D, Wälchli S, Helland Å, Inderberg EM (2022)
A phase I/II escalation trial design T-RAD: Treatment of metastatic lung cancer with mRNA-engineered T cells expressing a T cell receptor targeting human telomerase reverse transcriptase (hTERT)
Front Oncol, 12, 1031232
DOI 10.3389/fonc.2022.1031232, PubMed 36439452

Publications 2021

Dillard P, Casey N, Pollmann S, Vernhoff P, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2021)
Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
Oncoimmunology, 10 (1), 1936757
DOI 10.1080/2162402X.2021.1936757, PubMed 34235003

Mensali N, Dillard P, Fayzullin A, Köksal H, Gaudernack G, Kvalheim G, Inderberg EM, Wälchli S (2021)
"Built-in" PD-1 blocker to rescue NK-92 activity from PD-L1-mediated tumor escape mechanisms
FASEB J, 35 (9), e21750
DOI 10.1096/fj.202100025R, PubMed 34424568

Tryggestad AMA, Axcrona K, Axcrona U, Bigalke I, Brennhovd B, Inderberg EM, Hønnåshagen TK, Skoge LJ, Solum G, Saebøe-Larssen S, Josefsen D, Olaussen RW, Aamdal S, Skotheim RI, Myklebust TÅ, Schendel DJ, Lilleby W, Dueland S, Kvalheim G (2021)
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy
Prostate, 82 (2), 245-253
DOI 10.1002/pros.24267, PubMed 34762317

Publications 2020

Dillard P, Köksal H, Maggadottir SM, Winge-Main A, Pollmann S, Menard M, Myhre MR, Mælandsmo GM, Flørenes VA, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
Mol Ther, 29 (3), 1199-1213
DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301

Köksal H, Dillard P, Juzeniene A, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S (2020)
Combinatorial CAR design improves target restriction
J Biol Chem, 296, 100116
DOI 10.1074/jbc.RA120.016234, PubMed 33234592

Lichtenegger FS, Schnorfeil FM, Rothe M, Deiser K, Altmann T, Bücklein VL, Köhnke T, Augsberger C, Konstandin NP, Spiekermann K, Moosmann A, Boehm S, Boxberg M, Heemskerk MH, Goerlich D, Wittmann G, Wagner B, Hiddemann W, Schendel DJ, Kvalheim G, Bigalke I, Subklewe M (2020)
Toll-like receptor 7/8-matured RNA-transduced dendritic cells as post-remission therapy in acute myeloid leukaemia: results of a phase I trial
Clin Transl Immunology, 9 (3), e1117
DOI 10.1002/cti2.1117, PubMed 32153780

Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
Correction to: Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
Cancer Immunol Immunother, 69 (1), 159-161
DOI 10.1007/s00262-019-02409-6, PubMed 31776597

Publications 2019

Andersson Y, Inderberg EM, Kvalheim G, Herud TM, Engebraaten O, Flatmark K, Dueland S, Fodstad Ø (2019)
Immune stimulatory effect of anti-EpCAM immunotoxin - improved overall survival of metastatic colorectal cancer patients
Acta Oncol, 59 (4), 404-409
DOI 10.1080/0284186X.2019.1704864, PubMed 31876430

Camilio KA, Wang MY, Mauseth B, Waagene S, Kvalheim G, Rekdal Ø, Sveinbjørnsson B, Mælandsmo GM (2019)
Combining the oncolytic peptide LTX-315 with doxorubicin demonstrates therapeutic potential in a triple-negative breast cancer model
Breast Cancer Res, 21 (1), 9
DOI 10.1186/s13058-018-1092-x, PubMed 30670061

Köksal H, Dillard P, Josefsson SE, Maggadottir SM, Pollmann S, Fåne A, Blaker YN, Beiske K, Huse K, Kolstad A, Holte H, Kvalheim G, Smeland EB, Myklebust JH, Inderberg EM, Wälchli S (2019)
Preclinical development of CD37CAR T-cell therapy for treatment of B-cell lymphoma
Blood Adv, 3 (8), 1230-1243
DOI 10.1182/bloodadvances.2018029678, PubMed 30979721

Mensali N, Dillard P, Hebeisen M, Lorenz S, Theodossiou T, Myhre MR, Fåne A, Gaudernack G, Kvalheim G, Myklebust JH, Inderberg EM, Wälchli S (2019)
NK cells specifically TCR-dressed to kill cancer cells
EBioMedicine, 40, 106-117
DOI 10.1016/j.ebiom.2019.01.031, PubMed 30665853

Mensali N, Grenov A, Pati NB, Dillard P, Myhre MR, Gaudernack G, Kvalheim G, Inderberg EM, Bakke O, Wälchli S (2019)
Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
Oncoimmunology, 8 (3), 1558663
DOI 10.1080/2162402X.2018.1558663, PubMed 30723591

Mensali N, Myhre MR, Dillard P, Pollmann S, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2019)
Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
Cancer Immunol Immunother, 68 (8), 1235-1243
DOI 10.1007/s00262-019-02356-2, PubMed 31214732

Publications 2017

Eide N, Faye RS, Høifødt HK, Sandvik L, Qvale GA, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2017)
The Results of Stricter Inclusion Criteria in an Immunomagnetic Detection Study of Micrometastatic Cells in Bone Marrow of Uveal Melanoma Patients - Relevance for Dormancy
Pathol Oncol Res, 25 (1), 255-262
DOI 10.1007/s12253-017-0355-7, PubMed 29098521

Inderberg EM, Mensali N, Oksvold MP, Fallang LE, Fåne A, Skorstad G, Stenvik GE, Progida C, Bakke O, Kvalheim G, Myklebust JH, Wälchli S (2017)
Human c-SRC kinase (CSK) overexpression makes T cells dummy
Cancer Immunol Immunother, 67 (4), 525-536
DOI 10.1007/s00262-017-2105-9, PubMed 29248956

Inderberg EM, Wälchli S, Myhre MR, Trachsel S, Almåsbak H, Kvalheim G, Gaudernack G (2017)
T cell therapy targeting a public neoantigen in microsatellite instable colon cancer reduces in vivo tumor growth
Oncoimmunology, 6 (4), e1302631
DOI 10.1080/2162402X.2017.1302631, PubMed 28507809

Li X, Grigalavicius M, Li Y, Li X, Zhong Y, Huang R, Yu D, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
MtDNA depletion influences the transition of CD44 subtypes in human prostate cancer DU145 cells
Tumour Biol, 39 (8), 1010428317713671
DOI 10.1177/1010428317713671, PubMed 28789597

Li X, Lu J, Kan Q, Li X, Fan Q, Li Y, Huang R, Slipicevic A, Dong HP, Eide L, Wang J, Zhang H, Berge V, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells
Sci Rep, 7 (1), 5081
DOI 10.1038/s41598-017-05086-6, PubMed 28698547

Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen RG, Peng Q, Wang J, Zhang H, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2017)
Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
Oncotarget, 8 (4), 7208-7213
DOI 10.18632/oncotarget.14800, PubMed 28179591

Nestvold J, Wang MY, Camilio KA, Zinöcker S, Tjelle TE, Lindberg A, Haug BE, Kvalheim G, Sveinbjørnsson B, Rekdal Ø (2017)
Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model
Oncoimmunology, 6 (8), e1338236
DOI 10.1080/2162402X.2017.1338236, PubMed 28920000

Schive SW, Mirlashari MR, Hasvold G, Wang M, Josefsen D, Gullestad HP, Korsgren O, Foss A, Kvalheim G, Scholz H (2017)
Human Adipose-Derived Mesenchymal Stem Cells Respond to Short-Term Hypoxia by Secreting Factors Beneficial for Human Islets In Vitro and Potentiate Antidiabetic Effect In Vivo
Cell Med, 9 (3), 103-116
DOI 10.3727/215517917X693401, PubMed 28713640

Walseng E, Köksal H, Sektioglu IM, Fåne A, Skorstad G, Kvalheim G, Gaudernack G, Inderberg EM, Wälchli S (2017)
A TCR-based Chimeric Antigen Receptor
Sci Rep, 7 (1), 10713
DOI 10.1038/s41598-017-11126-y, PubMed 28878363

Wang MY, Nestvold J, Rekdal Ø, Kvalheim G, Fodstad Ø (2017)
A novel rat fibrosarcoma cell line from transformed bone marrow-derived mesenchymal stem cells with maintained in vitro and in vivo stemness properties
Exp Cell Res, 352 (2), 218-224
DOI 10.1016/j.yexcr.2017.02.005, PubMed 28189639

Publications 2016

Kyte JA, Gaudernack G, Faane A, Lislerud K, Inderberg EM, Brunsvig P, Aamdal S, Kvalheim G, Wälchli S, Pule M (2016)
T-helper cell receptors from long-term survivors after telomerase cancer vaccination for use in adoptive cell therapy
Oncoimmunology, 5 (12), e1249090
DOI 10.1080/2162402X.2016.1249090, PubMed 28123886

Kyte JA, Aamdal S, Dueland S, Sæbøe-Larsen S, Inderberg EM, Madsbu UE, Skovlund E, Gaudernack G, Kvalheim G (2016)
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
Oncoimmunology, 5 (11), e1232237
DOI 10.1080/2162402X.2016.1232237, PubMed 27999747

Li X, Zhong Y, Lu J, Axcrona K, Eide L, Syljuåsen RG, Peng Q, Wang J, Zhang H, Goscinski MA, Kvalheim G, Nesland JM, Suo Z (2016)
MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
Oncotarget, 7 (26), 40297-40313
DOI 10.18632/oncotarget.9610, PubMed 27248169

Schive SW, Foss A, Sahraoui A, Kloster-Jensen K, Hafsahl G, Kvalheim G, Lundgren T, von Zur-Mühlen B, Felldin M, Rafael E, Lempinen M, Korsgren O, Jenssen TG, Mishra V, Scholz H (2016)
Cost and clinical outcome of islet transplantation in Norway 2010-2015
Clin Transplant, 31 (1)
DOI 10.1111/ctr.12871, PubMed 27862341

Sioud M, Nyakas M, Sæbøe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G (2016)
Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
Case Rep Med, 2016, 9639585
DOI 10.1155/2016/9639585, PubMed 27504122

Publications 2015

Almåsbak H, Walseng E, Kristian A, Myhre MR, Suso EM, Munthe LA, Andersen JT, Wang MY, Kvalheim G, Gaudernack G, Kyte JA (2015)
Inclusion of an IgG1-Fc spacer abrogates efficacy of CD19 CAR T cells in a xenograft mouse model
Gene Ther, 22 (5), 391-403
DOI 10.1038/gt.2015.4, PubMed 25652098

Eide N, Faye RS, Høifødt HK, Sandstad B, Qvale G, Faber R, Jebsen P, Kvalheim G, Fodstad Ø (2015)
Immunomagnetic detection of micrometastatic cells in bone marrow of uveal melanoma patients: a paradox
Acta Ophthalmol, 93 (1), 59-66
DOI 10.1111/aos.12462, PubMed 25613126

Yu D, Zhong Y, Li X, Li Y, Li X, Cao J, Fan H, Yuan Y, Ji Z, Qiao B, Wen JG, Zhang M, Kvalheim G, Nesland JM, Suo Z (2015)
ILs-3, 6 and 11 increase, but ILs-10 and 24 decrease stemness of human prostate cancer cells in vitro
Oncotarget, 6 (40), 42687-703
DOI 10.18632/oncotarget.5883, PubMed 26528857

Publications 2014

Husøy MA, Brinch L, Tjønnfjord GE, Gedde-Dahl T, Heldal D, Holme PA, Dybedal I, Kolstad A, Akkök ÇA, Rollag H, Gaustad P, Bergan S, Egeland T, Josefsen D, Kvalheim G, Fløisand Y (2014)
[Allogeneic stem-cell transplantation in adults 1985-2012: results and development]
Tidsskr Nor Laegeforen, 134 (16), 1569-75
DOI 10.4045/tidsskr.13.1415, PubMed 25178233

Kolstad A, Kumari S, Walczak M, Madsbu U, Hagtvedt T, Bogsrud TV, Kvalheim G, Holte H, Aurlien E, Delabie J, Tierens A, Olweus J (2014)
Sequential intranodal immunotherapy induces antitumor immunity and correlated regression of disseminated follicular lymphoma
Blood, 125 (1), 82-9
DOI 10.1182/blood-2014-07-592162, PubMed 25293773

Skårn M, Noordhuis P, Wang MY, Veuger M, Kresse SH, Egeland EV, Micci F, Namløs HM, Håkelien AM, Olafsrud SM, Lorenz S, Haraldsen G, Kvalheim G, Meza-Zepeda LA, Myklebost O (2014)
Generation and characterization of an immortalized human mesenchymal stromal cell line
Stem Cells Dev, 23 (19), 2377-89
DOI 10.1089/scd.2013.0599, PubMed 24857590

Subklewe M, Geiger C, Lichtenegger FS, Javorovic M, Kvalheim G, Schendel DJ, Bigalke I (2014)
New generation dendritic cell vaccine for immunotherapy of acute myeloid leukemia
Cancer Immunol Immunother, 63 (10), 1093-103
DOI 10.1007/s00262-014-1600-5, PubMed 25186611

Woll PS, Kjällquist U, Chowdhury O, Doolittle H, Wedge DC, Thongjuea S, Erlandsson R, Ngara M, Anderson K, Deng Q, Mead AJ, Stenson L, Giustacchini A, Duarte S, Giannoulatou E, Taylor S, Karimi M, Scharenberg C, Mortera-Blanco T, Macaulay IC, Clark SA, Dybedal I, Josefsen D, Fenaux P, Hokland P et al. (2014)
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo
Cancer Cell, 25 (6), 794-808
DOI 10.1016/j.ccr.2014.03.036, PubMed 24835589

Publications 2013

Kaur K, Mirlashari MR, Kvalheim G, Kjeldsen-Kragh J (2013)
3',4'-Dimethoxyflavone and valproic acid promotes the proliferation of human hematopoietic stem cells
Stem Cell Res Ther, 4 (3), 60
DOI 10.1186/scrt208, PubMed 23706670

Liu Y, Wu X, Li X, Kvalheim G, Axcrona U, Axcrona K, Suo Z (2013)
Blocking mtDNA replication upregulates the expression of stemness-related genes in prostate cancer cell lines
Ultrastruct Pathol, 37 (4), 258-66
DOI 10.3109/01913123.2013.770112, PubMed 23634795

Ma Y, Liang D, Liu J, Wen JG, Servoll E, Waaler G, Sæter T, Axcrona K, Vlatkovic L, Axcrona U, Paus E, Yang Y, Zhang Z, Kvalheim G, Nesland JM, Suo Z (2013)
SHBG is an important factor in stemness induction of cells by DHT in vitro and associated with poor clinical features of prostate carcinomas
PLoS One, 8 (7), e70558 (Retracted)
DOI 10.1371/journal.pone.0070558, PubMed 23936228

Sioud M, Saebøe-Larssen S, Hetland TE, Kaern J, Mobergslien A, Kvalheim G (2013)
Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients
Int J Oncol, 43 (1), 280-8
DOI 10.3892/ijo.2013.1922, PubMed 23620105

Smeland KB, Kiserud CE, Lauritzsen GF, Fosså A, Hammerstrøm J, Jetne V, Kolstad A, Kvalheim G, Loge JH, Løkeland T, Tangen JM, Holte H, Kvaløy S (2013)
High-dose therapy with autologous stem cell support for lymphoma--from experimental to standard treatment
Tidsskr Nor Laegeforen, 133 (16), 1735-9
DOI 10.4045/tidsskr.13.0319, PubMed 24005713

Vik-Mo EO, Nyakas M, Mikkelsen BV, Moe MC, Due-Tønnesen P, Suso EM, Sæbøe-Larssen S, Sandberg C, Brinchmann JE, Helseth E, Rasmussen AM, Lote K, Aamdal S, Gaudernack G, Kvalheim G, Langmoen IA (2013)
Therapeutic vaccination against autologous cancer stem cells with mRNA-transfected dendritic cells in patients with glioblastoma
Cancer Immunol Immunother, 62 (9), 1499-509
DOI 10.1007/s00262-013-1453-3, PubMed 23817721

Wang P, Gao Q, Suo Z, Munthe E, Solberg S, Ma L, Wang M, Westerdaal NA, Kvalheim G, Gaudernack G (2013)
Identification and characterization of cells with cancer stem cell properties in human primary lung cancer cell lines
PLoS One, 8 (3), e57020 (Retracted)
DOI 10.1371/journal.pone.0057020, PubMed 23469181

Wang P, Suo Z, Wang M, Høifødt HK, Fodstad O, Gaudernack G, Kvalheim G (2013)
In vitro and in vivo properties of CD133 expressing cells from human lung cancer cell lines
Exp Hematol Oncol, 2 (1), 16
DOI 10.1186/2162-3619-2-16, PubMed 23738757

Publications 2012

Eide N, Hoifødt HK, Nesland JM, Faye RS, Qvale GA, Faber RT, Jebsen P, Kvalheim G, Fodstad Ø (2012)
Disseminated tumour cells in bone marrow of patients with uveal melanoma
Acta Ophthalmol, 91 (4), 343-8
DOI 10.1111/j.1755-3768.2012.02449.x, PubMed 22632270

Fløisand Y, Brinch L, Gedde-Dahl T, Tjønnfjord GE, Dybedal I, Holte H, Heldal D, Torfoss D, Aurlien E, Lauritzsen GF, Fosså A, Lehne G, Baggerød E, Kvalheim G, Egeland T, Bishop MR, Fowler DH, Kolstad A (2012)
Ultra-short course sirolimus contributes to effective GVHD prophylaxis after reduced-intensity allogeneic hematopoietic cell transplantation
Bone Marrow Transplant, 47 (12), 1552-7
DOI 10.1038/bmt.2012.63, PubMed 22522568

Langmoen IA, Foss A, Kvalheim G, Engebretsen L, Glover JC (2012)
[Stem cell research--new hope?]
Tidsskr Nor Laegeforen, 132 (23-24), 2584
DOI 10.4045/tidsskr.12.1324, PubMed 23338066

Ma Y, Liang D, Liu J, Axcrona K, Kvalheim G, Giercksky KE, Nesland JM, Suo Z (2012)
Synergistic effect of SCF and G-CSF on stem-like properties in prostate cancer cell lines
Tumour Biol, 33 (4), 967-78
DOI 10.1007/s13277-012-0325-3, PubMed 22252524

Mathiesen RR, Borgen E, Renolen A, Løkkevik E, Nesland JM, Anker G, Ostenstad B, Lundgren S, Risberg T, Mjaaland I, Kvalheim G, Lønning PE, Naume B (2012)
Persistence of disseminated tumor cells after neoadjuvant treatment for locally advanced breast cancer predicts poor survival
Breast Cancer Res, 14 (4), R117
DOI 10.1186/bcr3242, PubMed 22889108

Publications 2011

Eide MB, Lauritzsen GF, Kvalheim G, Kolstad A, Fagerli UM, Maisenhölder M, Østenstad B, Fluge Ø, Delabie J, Aarset H, Liestøl K, Holte H (2011)
High dose chemotherapy with autologous stem cell support for patients with histologically transformed B-cell non-Hodgkin lymphomas. A Norwegian multi centre phase II study
Br J Haematol, 152 (5), 600-10
DOI 10.1111/j.1365-2141.2010.08519.x, PubMed 21241276

Hetland G, Johnson E, Lyberg T, Kvalheim G (2011)
The Mushroom Agaricus blazei Murill Elicits Medicinal Effects on Tumor, Infection, Allergy, and Inflammation through Its Modulation of Innate Immunity and Amelioration of Th1/Th2 Imbalance and Inflammation
Adv Pharmacol Sci, 2011, 157015
DOI 10.1155/2011/157015, PubMed 21912538

Josefsen D, Forfang L, Dyrhaug M, Blystad AK, Stokke T, Smeland EB, Kvalheim G (2011)
Side population cells in highly enriched CD34-positive cells from peripheral blood progenitor cells identify an immature subtype of hematopoietic progenitor cells but do not predict time to engraftment in patients treated with high-dose therapy
Eur J Haematol, 87 (6), 494-502
DOI 10.1111/j.1600-0609.2011.01681.x, PubMed 21752097

Ma Y, Liang D, Liu J, Axcrona K, Kvalheim G, Stokke T, Nesland JM, Suo Z (2011)
Prostate cancer cell lines under hypoxia exhibit greater stem-like properties
PLoS One, 6 (12), e29170 (Retracted)
DOI 10.1371/journal.pone.0029170, PubMed 22216200

Mohty M, Duarte RF, Croockewit S, Hübel K, Kvalheim G, Russell N (2011)
The role of plerixafor in optimizing peripheral blood stem cell mobilization for autologous stem cell transplantation
Leukemia, 25 (1), 1-6
DOI 10.1038/leu.2010.224, PubMed 21224858

Suso EM, Dueland S, Rasmussen AM, Vetrhus T, Aamdal S, Kvalheim G, Gaudernack G (2011)
hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
Cancer Immunol Immunother, 60 (6), 809-18
DOI 10.1007/s00262-011-0991-9, PubMed 21365467

Torfoss D, Sandstad B, Mollnes TE, Høiby EA, Holte H, Bjerner J, Bjøro T, Gaudernack G, Kvalheim G, Kvaløy S (2011)
The mild inflammatory response in febrile neutropenic lymphoma patients with low risk of complications is more pronounced in patients receiving tobramycin once daily compared with three times daily
Scand J Immunol, 74 (6), 632-9
DOI 10.1111/j.1365-3083.2011.02618.x, PubMed 21883353

Zinöcker S, Wang MY, Gaustad P, Kvalheim G, Rolstad B, Vaage JT (2011)
Mycoplasma contamination revisited: mesenchymal stromal cells harboring Mycoplasma hyorhinis potently inhibit lymphocyte proliferation in vitro
PLoS One, 6 (1), e16005
DOI 10.1371/journal.pone.0016005, PubMed 21264307

Publications 2010

Almåsbak H, Rian E, Hoel HJ, Pulè M, Wälchli S, Kvalheim G, Gaudernack G, Rasmussen AM (2010)
Transiently redirected T cells for adoptive transfer
Cytotherapy, 13 (5), 629-40
DOI 10.3109/14653249.2010.542461, PubMed 21174490

Jantunen E, Kvalheim G (2010)
Mobilization strategies in hard-to-mobilize patients with lymphoid malignancies
Eur J Haematol, 85 (6), 463-71
DOI 10.1111/j.1600-0609.2010.01520.x, PubMed 20738393

Johnsen HE, Geisler C, Juvonen E, Remes K, Juliusson G, Hörnsten P, Kvaloy S, Kvalheim G, Jürgensen GW, Pedersen LM, Bergmann OJ, Schmitz A, Boegsted M (2010)
Priming with r-metHuSCF and filgrastim or chemotherapy and filgrastim in patients with malignant lymphomas: a randomized phase II pilot study of mobilization and engraftment
Bone Marrow Transplant, 46 (1), 44-51
DOI 10.1038/bmt.2010.84, PubMed 20436517

Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Stromberg M, Wiedswang G, Kvalheim G, Karesen R, Nesland JM, Borresen-Dale AL, Sorlie T (2010)
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer (vol 1, pg 160, 2007)
Mol. Oncol., 4 (2), 169
DOI 10.1016/j.molonc.2010.01.003

Rasmussen AM, Borelli G, Hoel HJ, Lislerud K, Gaudernack G, Kvalheim G, Aarvak T (2010)
Ex vivo expansion protocol for human tumor specific T cells for adoptive T cell therapy
J Immunol Methods, 355 (1-2), 52-60
DOI 10.1016/j.jim.2010.02.004, PubMed 20171968

Tamburstuen MV, Reppe S, Spahr A, Sabetrasekh R, Kvalheim G, Slaby I, Syversen U, Lyngstadaas SP, Reseland JE (2010)
Ameloblastin promotes bone growth by enhancing proliferation of progenitor cells and by stimulating immunoregulators
Eur J Oral Sci, 118 (5), 451-9
DOI 10.1111/j.1600-0722.2010.00760.x, PubMed 20831578

Tamburstuen MV, Reseland JE, Spahr A, Brookes SJ, Kvalheim G, Slaby I, Snead ML, Lyngstadaas SP (2010)
Ameloblastin expression and putative autoregulation in mesenchymal cells suggest a role in early bone formation and repair
Bone, 48 (2), 406-13
DOI 10.1016/j.bone.2010.09.007, PubMed 20854943

Publications 2009

Eide N, Faye RS, Høifødt HK, Øvergaard R, Jebsen P, Kvalheim G, Fodstad Ø (2009)
Immunomagnetic detection of micrometastatic cells in bone marrow in uveal melanoma patients
Acta Ophthalmol, 87 (8), 830-6
DOI 10.1111/j.1755-3768.2008.01378.x, PubMed 19055657

Gao Q, Geng L, Kvalheim G, Gaudernack G, Suo Z (2009)
Identification of cancer stem-like side population cells in ovarian cancer cell line OVCAR-3
Ultrastruct Pathol, 33 (4), 175-81
DOI 10.1080/01913120903086072, PubMed 19728235

Huang TS, Grodeland G, Sleire L, Wang MY, Kvalheim G, Laerum OD (2009)
Induction of circadian rhythm in cultured human mesenchymal stem cells by serum shock and cAMP analogs in vitro
Chronobiol Int, 26 (2), 242-57
DOI 10.1080/07420520902766025, PubMed 19212839

Publications 2008

Lazarova P, Kvalheim G, Gercheva L, Metodiev K (2008)
Experimental attempt to produce mRNA transfected dendritic cells derived from enriched CD34+blood progenitor cells
Cent. Eur. J. Med., 3 (1), 21-28
DOI 10.2478/s11536-007-0072-9

Publications 2007

Berg A, Berner A, Lilleby W, Bruland ØS, Fosså SD, Nesland JM, Kvalheim G (2007)
Impact of disseminated tumor cells in bone marrow at diagnosis in patients with nonmetastatic prostate cancer treated by definitive radiotherapy
Int J Cancer, 120 (8), 1603-9
DOI 10.1002/ijc.22488, PubMed 17230512

Jarnjak-Jankovic S, Hammerstad H, Saebøe-Larssen S, Kvalheim G, Gaudernack G (2007)
A full scale comparative study of methods for generation of functional Dendritic cells for use as cancer vaccines
BMC Cancer, 7, 119
DOI 10.1186/1471-2407-7-119, PubMed 17608923

Jarnjak-Jankovic S, Saebøe-Larssen S, Kvalheim G, Gaudernack G (2007)
mRNA transfection of DC in the immature or mature state: comparable in vitro priming of Th and cytotoxic T lymphocytes against DC electroporated with tumor cell line-derived mRNA
Cytotherapy, 9 (6), 587-92
DOI 10.1080/14653240701466354, PubMed 17882723

Naume B, Zhao X, Synnestvedt M, Borgen E, Russnes HG, Lingjaerde OC, Strømberg M, Wiedswang G, Kvalheim G, Kåresen R, Nesland JM, Børresen-Dale AL, Sørlie T (2007)
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
Mol Oncol, 1 (2), 160-71
DOI 10.1016/j.molonc.2007.03.004, PubMed 19383292

Publications 2006

Brunsvig PF, Aamdal S, Gjertsen MK, Kvalheim G, Markowski-Grimsrud CJ, Sve I, Dyrhaug M, Trachsel S, Møller M, Eriksen JA, Gaudernack G (2006)
Telomerase peptide vaccination: a phase I/II study in patients with non-small cell lung cancer
Cancer Immunol Immunother, 55 (12), 1553-64
DOI 10.1007/s00262-006-0145-7, PubMed 16491401

Davidson B, Konstantinovsky S, Kleinberg L, Nguyen MT, Bassarova A, Kvalheim G, Nesland JM, Reich R (2006)
The mitogen-activated protein kinases (MAPK) p38 and JNK are markers of tumor progression in breast carcinoma
Gynecol Oncol, 102 (3), 453-61
DOI 10.1016/j.ygyno.2006.01.034, PubMed 16494928

Drageset V, Nesland JM, Erikstein B, Skovlund E, Sommer H, Anker G, Wist E, Lundgren S, Bergh J, Kvalheim G (2006)
Monitoring of disseminated tumor cells in bone marrow in high-risk breast cancer patients treated with high-dose chemotherapy
Int J Cancer, 118 (11), 2877-81
DOI 10.1002/ijc.21709, PubMed 16381016

Gratama J, Kvalheim G, Orfao A (2006)
Standardization of cell analysis methods in clinical cellular therapy programs: A challenge for ISCT
Cytotherapy, 8 (6), 528-9
DOI 10.1080/14653240601056354, PubMed 17148028

Kyte JA, Kvalheim G, Lislerud K, thor Straten P, Dueland S, Aamdal S, Gaudernack G (2006)
T cell responses in melanoma patients after vaccination with tumor-mRNA transfected dendritic cells
Cancer Immunol Immunother, 56 (5), 659-75
DOI 10.1007/s00262-006-0222-y, PubMed 16947019

Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M, Gullestad HP, Ryder T, Lislerud K, Hammerstad H, Gaudernack G (2006)
Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
Cancer Gene Ther, 13 (10), 905-18
DOI 10.1038/sj.cgt.7700961, PubMed 16710345

Lazarova P, Wu Q, Kvalheim G, Suo Z, Haakenstad KW, Metodiev K, Nesland JM (2006)
Growth factor receptors in hematopoietic stem cells: EPH family expression in CD34+ and CD133+ cell populations from mobilized peripheral blood
Int J Immunopathol Pharmacol, 19 (1), 49-56
PubMed 16569339

Wiedswang G, Borgen E, Schirmer C, Kåresen R, Kvalheim G, Nesland JM, Naume B (2006)
Comparison of the clinical significance of occult tumor cells in blood and bone marrow in breast cancer
Int J Cancer, 118 (8), 2013-9
DOI 10.1002/ijc.21576, PubMed 16287086

Publications 2005

Elloul S, Elstrand MB, Nesland JM, Tropé CG, Kvalheim G, Goldberg I, Reich R, Davidson B (2005)
Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma
Cancer, 103 (8), 1631-43
DOI 10.1002/cncr.20946, PubMed 15742334

Konstantinovsky S, Nielsen S, Vyberg M, Kvalheim G, Nesland JM, Reich R, Davidson B (2005)
Angiogenic molecule expression is downregulated in effusions from breast cancer patients
Breast Cancer Res Treat, 94 (1), 71-80
DOI 10.1007/s10549-005-7328-3, PubMed 16142438

Kvalheim G (2005)
Stem cell therapy still not here
Cytotherapy, 7 (5), 456-7
DOI 10.1080/14653240500319267, PubMed 16236635

Kyte JA, Kvalheim G, Aamdal S, Saebøe-Larssen S, Gaudernack G (2005)
Preclinical full-scale evaluation of dendritic cells transfected with autologous tumor-mRNA for melanoma vaccination
Cancer Gene Ther, 12 (6), 579-91
DOI 10.1038/sj.cgt.7700837, PubMed 15818380

Mu LJ, Kyte JA, Kvalheim G, Aamdal S, Dueland S, Hauser M, Hammerstad H, Waehre H, Raabe N, Gaudernack G (2005)
Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
Br J Cancer, 93 (7), 749-56
DOI 10.1038/sj.bjc.6602761, PubMed 16136047

Publications 2004

Blystad AK, Delabie J, Kvaløy S, Holte H, Vålerhaugen H, Ikonomou I, Kvalheim G (2004)
Infused CD34 cell dose, but not tumour cell content of peripheral blood progenitor cell grafts, predicts clinical outcome in patients with diffuse large B-cell lymphoma and follicular lymphoma grade 3 treated with high-dose therapy
Br J Haematol, 125 (5), 605-12
DOI 10.1111/j.1365-2141.2004.04951.x, PubMed 15147376

Lazarova P, Lijun M, Hammerstad H, Nesland J, Gaudernack G, Kvalheim G (2004)
Experimental attempt to introduce a vaccine therapy by using DC-developed from CD34+cells
NATO SCI SER I LIFE, 361, 134

Mu LJ, Lazarova P, Gaudernack G, Saeboe-Larssen S, Kvalheim G (2004)
Development of a clinical grade procedure for generation of mRNA transfected dendritic cells from purified frozen CD34(+) blood progenitor cells
Int J Immunopathol Pharmacol, 17 (3), 255-63
DOI 10.1177/039463200401700305, PubMed 15461859

Naume B, Wiedswang G, Borgen E, Kvalheim G, Karesen R, Quist H, Janbu J, Harbitz TB, Nesland JM (2004)
The prognostic value of isolated tumor cells in bone marrow in breast cancer patients: evaluation of morphological categories and the number of clinically significant cells
In Clinical cancer research, AACR Publications Department, Philadelphia, PA, 10(2004)9, S. 3091-7
BIBSYS 05181322x

Naume B, Wiedswang G, Borgen E, Kvalheim G, Kåresen R, Qvist H, Janbu J, Harbitz T, Nesland JM (2004)
The prognostic value of isolated tumor cells in bone marrow in breast cancer patients: evaluation of morphological categories and the number of clinically significant cells
Clin Cancer Res, 10 (9), 3091-7
DOI 10.1158/1078-0432.ccr-03-0373, PubMed 15131048

Smeland S, Blystad AK, Kvaløy SO, Ikonomou IM, Delabie J, Kvalheim G, Hammerstrøm J, Lauritzsen GF, Holte H (2004)
Treatment of Burkitt's/Burkitt-like lymphoma in adolescents and adults: a 20-year experience from the Norwegian Radium Hospital with the use of three successive regimens
Ann Oncol, 15 (7), 1072-8
DOI 10.1093/annonc/mdh262, PubMed 15205201

Wiedswang G, Borgen E, Kåresen R, Qvist H, Janbu J, Kvalheim G, Nesland JM, Naume B (2004)
Isolated tumor cells in bone marrow three years after diagnosis in disease-free breast cancer patients predict unfavorable clinical outcome
Clin Cancer Res, 10 (16), 5342-8
DOI 10.1158/1078-0432.CCR-04-0245, PubMed 15328170

Østby I, Kvalheim G, Rusten LS, Grøttum P (2004)
Mathematical modeling of granulocyte reconstitution after high-dose chemotherapy with stem cell support: effect of post-transplant G-CSF treatment
J Theor Biol, 231 (1), 69-83
DOI 10.1016/j.jtbi.2004.05.010, PubMed 15363930

Publications 2003

Kvalheim G, Gratwohl A, Urbano-Ispizua A, JACIE national representatives (2003)
JACIE accreditation in Europe moves ahead
Cytotherapy, 5 (4), 306-8
DOI 10.1080/14653240310002216, PubMed 12944236

Lilleby W, Nesland JM, Fosså SD, Torlakovic G, Waehre H, Kvalheim G (2003)
The prognostic impact of cytokeratin-positive cells in bone marrow of patients with localized prostate cancer
Int J Cancer, 103 (1), 91-6
DOI 10.1002/ijc.10780, PubMed 12455058

Mu LJ, Gaudernack G, Saebøe-Larssen S, Hammerstad H, Tierens A, Kvalheim G (2003)
A protocol for generation of clinical grade mRNA-transfected monocyte-derived dendritic cells for cancer vaccines
Scand J Immunol, 58 (5), 578-86
DOI 10.1046/j.1365-3083.2003.01333.x, PubMed 14629630

Ogreid P, Kvalheim G (2003)
Old and new research into micrometastases in prostate cancer
Scand J Urol Nephrol Suppl (212), 37-9
PubMed 12841326

Ogreid P, Kvalheim G (2003)
Old and new research into micrometastases in prostate cancer
Scand. J. Urol. Nephrol., 37 212, 37-39
DOI 10.1080/03008880310006931

Schouten HC, Qian W, Kvaloy S, Porcellini A, Hagberg H, Johnsen HE, Doorduijn JK, Sydes MR, Kvalheim G (2003)
High-dose therapy improves progression-free survival and survival in relapsed follicular non-Hodgkin's lymphoma: results from the randomized European CUP trial
J Clin Oncol, 21 (21), 3918-27
DOI 10.1200/JCO.2003.10.023, PubMed 14517188

Taraldsrud E, Kvalheim G, Jørstad S, Stavem K, Aandahl GS (2003)
A survey of therapeutic hemapheresis in Norway year 2000
Transfus Apher Sci, 28 (2), 135-41
DOI 10.1016/S1473-0502(03)00004-1, PubMed 12679117

Taraldsrud E, Aandahl GS, Stavem K, Kvalheim G, Jørstad S (2003)
[Therapeutic hemapheresis]
Tidsskr Nor Laegeforen, 123 (17), 2439-42
PubMed 14594145

Wiedswang G, Borgen E, Kåresen R, Kvalheim G, Nesland JM, Qvist H, Schlichting E, Sauer T, Janbu J, Harbitz T, Naume B (2003)
Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer
J Clin Oncol, 21 (18), 3469-78
DOI 10.1200/JCO.2003.02.009, PubMed 12972522

Wiedswang G, Borgen E, Kåresen R, Kvalheim G, Nesland JM, Qvist HL, Schlichting E, Sauer T, Janbu J, Harbitz TB, Naume B (2003)
Detection of isolated tumor cells in bone marrow is an independent prognostic factor in breast cancer
In Journal of clinical oncology, The Society, Alexandria VA, 21(2003)18, s.3469-78
BIBSYS 041728920

Østby I, Rusten LS, Kvalheim G, Grøttum P (2003)
A mathematical model for reconstitution of granulopoiesis after high dose chemotherapy with autologous stem cell transplantation
J Math Biol, 47 (2), 101-36
DOI 10.1007/s00285-003-0198-6, PubMed 12883857

Publications 2001

Aurlien E, Holte H, Kvaloy S, Jakobsen E, Rusten LS, Kvalheim G (2001)
Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
Eur. J. Haematol., 66 64, 14-20

Aurlien E, Holte H, Kvaløy S, Jakobsen E, Rusten LS, Kvalheim G (2001)
Combination chemotherapy containing mitoguazone, ifosfamide, methotrexate, etoposide (MIME) and G-CSF efficiently mobilize peripheral blood progenitor cells in heavily pre-treated relapsed lymphoma patients
Eur J Haematol Suppl, 64, 14-20
PubMed 11486395

Blystad AK, Enblad G, Kvaløy S, Berglund A, Delabie J, Holte H, Carlson K, Kvalheim G, Bengtsson M, Hagberg H (2001)
High-dose therapy with autologous stem cell transplantation in patients with peripheral T cell lymphomas
Bone Marrow Transplant, 27 (7), 711-6
DOI 10.1038/sj.bmt.1702867, PubMed 11360110

Blystad AK, Holte H, Kvaløy S, Smeland E, Delabie J, Kvalheim G (2001)
High-dose therapy in patients with Hodgkin's disease: the use of selected CD34(+) cells is as safe as unmanipulated peripheral blood progenitor cells
Bone Marrow Transplant, 28 (9), 849-57
DOI 10.1038/sj.bmt.1703244, PubMed 11781645

Blystad AK, Torlakovic E, Holte H, Kvaløy S, Lenschow E, Kvalheim G (2001)
CD34(+) cell enrichment depletes atypical CD30(+) cells from PBPC grafts in patients with HD
Cytotherapy, 3 (4), 295-305
DOI 10.1080/146532401317070934, PubMed 12171718

Hall KS, Wiklund T, Erikstein B, Holte H, Kvalheim G, Sommer HH, Andersen A, Skovlund E, Bergh J, Hall C (2001)
Effects of dose-intensive chemotherapy and radiotherapy on serum n-terminal proatrial natriuretic peptide in high-risk breast cancer patients
Breast Cancer Res Treat, 67 (3), 235-44
DOI 10.1023/a:1017946315032, PubMed 11561769

Kvalheim G, Urbano-Ispizua A, Gratwohl A (2001)
Regulatory aspects and accreditation of the clinical use of hematopoietic progenitor cells in Europe
J Biol Regul Homeost Agents, 15 (1), 79-80
PubMed 11388748

Naume B, Borgen E, Kvalheim G, Kåresen R, Qvist H, Sauer T, Kumar T, Nesland JM (2001)
Detection of isolated tumor cells in bone marrow in early-stage breast carcinoma patients: comparison with preoperative clinical parameters and primary tumor characteristics
Clin Cancer Res, 7 (12), 4122-9
PubMed 11751511

Publications 2000

Aurlien E, Larsen RH, Kvalheim G, Bruland OS (2000)
Demonstration of highly specific toxicity of the alpha-emitting radioimmunoconjugate(211)At-rituximab against non-Hodgkin's lymphoma cells
Br J Cancer, 83 (10), 1375-9
DOI 10.1054/bjoc.2000.1453, PubMed 11044364

Publications 1999

Blystad A, Kvalheim G, Torlakovic E, Holte H, Jacobsen E, Beiske K, Vâlerhaugen H, Lenschow E, Kvaloy S (1999)
High-dose therapy supported with immunomagnetic purged autologous bone marrow in high-grade B cell non-Hodgkin's lymphoma
Bone Marrow Transplant, 24 (8), 865-72
DOI 10.1038/sj.bmt.1701990, PubMed 10516698

Borgen E, Naume B, Nesland JM, Kvalheim G, Beiske K, Fodstad O, Diel I, Solomayer EF, Theocharous P, Coombes RC, Smith BM, Wunder E, Marolleau JP, Garcia J, Pantel K (1999)
Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells
Cytotherapy, 1 (5), 377-88
DOI 10.1080/0032472031000141283, PubMed 20426539

Crown J, Coiffier B, Cortés-Funes H, Guillaume T, Kanz L, Kvalheim G, Marty M, Symann M (1999)
ESTIC position paper: high-dose chemotherapy for breast cancer, investigation should continue
Ann Oncol, 10 (8), 903-5
DOI 10.1023/a:1008396811371, PubMed 10509150

Davidson B, Risberg B, Kristensen G, Kvalheim G, Emilsen E, Bjåmer A, Berner A (1999)
Detection of cancer cells in effusions from patients diagnosed with gynaecological malignancies. Evaluation of five epithelial markers
Virchows Arch, 435 (1), 43-9
DOI 10.1007/s004280050393, PubMed 10431845

Kvalheim G, Berli M (1999)
EBMT and ISHAGE-Europe create a foundation for inspection and accreditation in Europe
Cytotherapy, 1 (5), 363-4
DOI 10.1080/0032472031000141280, PubMed 20426536

Kvalheim G, Naume B, Nesland JM (1999)
Minimal residual disease in breast cancer
Cancer Metastasis Rev, 18 (1), 101-8
DOI 10.1023/a:1006216504892, PubMed 10505549

Lindman H, Wiklund T, Holte H, Ljungman P, Blomqvist C, Kvalheim G, Bengtsson M, Höglund M, Wilking N, Bergh J (1999)
FEC mobilized stem cells for high-dose therapy in breast cancer patients. SB6 9401 Study Group
Acta Oncol, 38 (2), 239-45
DOI 10.1080/028418699431672, PubMed 10227447

Nordøy T, Kolstad A, Endresen P, Holte H, Kvaløy S, Kvalheim G, Husebekk A (1999)
Persistent changes in the immune system 4-10 years after ABMT
Bone Marrow Transplant, 24 (8), 873-8
DOI 10.1038/sj.bmt.1702006, PubMed 10516699

Serke S, Johnsen H, Huhn D, Kvalheim G (1999)
European survey of the flow cytometric determination of CD34-expressing cells
Cytotherapy, 1 (4), 343-7
DOI 10.1080/0032472031000141275, PubMed 20426564

Publications 1998

Aurlien E, Holte H, Pharo A, Kvaløy S, Jakobsen E, Smeland EB, Kvalheim G (1998)
Combination chemotherapy with mitoguazon, ifosfamide, MTX, etoposide (MIME) and G-CSF can efficiently mobilize PBPC in patients with Hodgkin's and non-Hodgkin's lymphoma
Bone Marrow Transplant, 21 (9), 873-8
DOI 10.1038/sj.bmt.1701192, PubMed 9613778

Borgen E, Beiske K, Trachsel S, Nesland JM, Kvalheim G, Herstad TK, Schlichting E, Qvist H, Naume B (1998)
Immunocytochemical detection of isolated epithelial cells in bone marrow: non-specific staining and contribution by plasma cells directly reactive to alkaline phosphatase
J Pathol, 185 (4), 427-34
DOI 10.1002/(SICI)1096-9896(199808)185:4<427::AID-PATH127>3.0.CO;2-7, PubMed 9828843

Kvalheim G (1998)
Diagnosis of minimal residual disease in bone marrow and blood in cancer patients--methods and clinical implications
Acta Oncol, 37 (5), 455-62
DOI 10.1080/028418698430403, PubMed 9831374

Kvalheim G (1998)
Detection and quantification of residual disease in bone marrow and PBPC
EUROCANCER 98, 19-21

Naume B, Borgen E, Nesland JM, Beiske K, Gilen E, Renolen A, Ravnås G, Qvist H, Kåresen R, Kvalheim G (1998)
Increased sensitivity for detection of micrometastases in bone-marrow/peripheral-blood stem-cell products from breast-cancer patients by negative immunomagnetic separation
Int J Cancer, 78 (5), 556-60
DOI 10.1002/(sici)1097-0215(19981123)78:5<556::aid-ijc5>3.0.co;2-g, PubMed 9808522

Oftung F, Borka E, Kvalheim G, Mustafa AS (1998)
Mycobacterial crossreactivity of M. tuberculosis reactive T cell clones from naturally converted PPD positive healthy subjects
FEMS Immunol Med Microbiol, 20 (3), 231-8
DOI 10.1111/j.1574-695X.1998.tb01131.x, PubMed 9566494

Publications 1997

Naume B, Borgen E, Beiske K, Herstad TK, Ravnås G, Renolen A, Trachsel S, Thrane-Steen K, Funderud S, Kvalheim G (1997)
Immunomagnetic techniques for the enrichment and detection of isolated breast carcinoma cells in bone marrow and peripheral blood
J Hematother, 6 (2), 103-14
DOI 10.1089/scd.1.1997.6.103, PubMed 9131439

Publications 1996

Atta J, Martin H, Bruecher J, Elsner S, Wassmann B, Rode C, Russ A, Kvalheim G, Hoelzer D (1996)
Residual leukemia and immunomagnetic bead purging in patients with BCR-ABL-positive acute lymphoblastic leukemia
Bone Marrow Transplant, 18 (3), 541-8
PubMed 8879615

Kolstad A, Holte H, Kvaløy S, Jakobsen E, Erikstein B, Aurlien E, Kvalheim G, Bøhler PJ, Langholm R (1996)
[High-dose therapy with autologous stem cell support in malignant lymphoma and breast cancer. Experiences with hematopoietic stem cells isolate from blood]
Tidsskr Nor Laegeforen, 116 (21), 2547-51
PubMed 8928122

Kongsgaard UE, Wang MY, Kvalheim G (1996)
Leucocyte depletion filter removes cancer cells in human blood
Acta Anaesthesiol Scand, 40 (1), 118-20
DOI 10.1111/j.1399-6576.1996.tb04397.x, PubMed 8904269

Kvalheim G (1996)
Purging of autografts: methods and clinical significance
Ann Med, 28 (2), 167-73
DOI 10.3109/07853899609092942, PubMed 8732646

Kvalheim G (1996)
Detection of occult tumour cells in bone marrow and blood in breast cancer patients--methods and clinical significance
Acta Oncol, 35 Suppl 8, 13-8
DOI 10.3109/02841869609098516, PubMed 9073044

Kvalheim G, Holte H, Jakobsen E, Kvaloy S (1996)
Immunomagnetic purging of lymphoma cells from autografts
J Hematother, 5 (5), 561-2
DOI 10.1089/scd.1.1996.5.561, PubMed 8938530

Kvalheim G, Pharo A, Holte H, Jakobsen E, Erikstein B, Kvaløy S, Beiske K, Nesland JM, Smeland EB (1996)
[High-dose therapy of cancer with CD34 positive cells as stem cell support]
Tidsskr Nor Laegeforen, 116 (21), 2542-6
PubMed 8928121

Kvalheim G, Wang MY, Pharo A, Holte H, Jacobsen E, Beiske K, Kvaløy S, Smeland E, Funderud S, Fodstad O (1996)
Purging of tumor cells from leukapheresis products: experimental and clinical aspects
J Hematother, 5 (4), 427-36
DOI 10.1089/scd.1.1996.5.427, PubMed 8877718

Publications 1995

Deggerdal AH, Pettersen F, Kvalheim G, Hornes E, Smeland E, Fodstad O, Hovig E (1995)
Semiquantitative polymerase chain reaction for t(14;18) in follicular lymphomas: a colorimetric approach
Lab Invest, 72 (4), 411-8
PubMed 7723279

Lundblad R, Wang MY, Kvalheim G, Lingaas E, Giercksky KE (1995)
Granulocyte colony-stimulating factor improves myelopoiesis and host defense in fulminant intra-abdominal sepsis in rats
Shock, 4 (1), 68-73
DOI 10.1097/00024382-199507000-00011, PubMed 7552781

Wang MY, Fodstad O, Ludwig WD, Bengtsson M, Totterman T, Funderub S, Martin H, Kvalheim G (1995)
An Effective, Direct Immunomagnetic Procedure for Purging Acute Lymphoblastic Leukemia Cells from Human Bone Marrow
Pathol Oncol Res, 1 (1), 32-37
DOI 10.1007/BF02893581, PubMed 11173565

Publications 1994

Kavløy S, Holte H, Kvalheim G (1994)
[High-dose autologous stem cell support in malignant diseases--an established method, uncertain indication]
Tidsskr Nor Laegeforen, 114 (19), 2240-1
PubMed 7992286

Kvalheim G, Jakobsen E, Holte H, Beiske K, Langholm R, Høiby A, Wang MY, Funderund S, Fodstad O, Smeland E (1994)
Autologous bone marrow transplantation of non-Hodgkin's lymphoma patients with marrow purged using immunomagnetic beads
Prog Clin Biol Res, 389, 133-8
PubMed 7700895

SCHNEEDE J, MORTENSEN JH, KVALHEIM G, UELAND PM (1994)
CAPILLARY ZONE ELECTROPHORESIS WITH LASER-INDUCED FLUORESCENCE DETECTION FOR ANALYSIS OF METHYLMALONIC ACID AND OTHER SHORT-CHAIN DICARBOXYLIC-ACIDS DERIVATIZED WITH 1-PYRENYLDIAZOMETHANE
J. Chromatogr. A, 669 (1-2), 185-193
DOI 10.1016/0021-9673(94)80347-1

Smeland EB, Rusten L, Jacobsen SE, Skrede B, Blomhoff R, Wang MY, Funderud S, Kvalheim G, Blomhoff HK (1994)
All-trans retinoic acid directly inhibits granulocyte colony-stimulating factor-induced proliferation of CD34+ human hematopoietic progenitor cells
Blood, 84 (9), 2940-5
DOI 10.1182/blood.V84.9.2940.bloodjournal8492940, PubMed 7524761

Wang MY, Fodstad O, Funderud S, Bengtsson M, Totterman T, Ludwig WD, Martin H, Kvalheim G (1994)
A direct and effective immunomagnetic method for bone marrow purging in non-T ALL malignancies. The use of an anti-HLA-DR antibody gives sustained engraftment
Prog Clin Biol Res, 389, 119-24
PubMed 7700893

Publications 1993

Fiskerstrand T, Refsum H, Kvalheim G, Ueland PM (1993)
Homocysteine and other thiols in plasma and urine: automated determination and sample stability
Clin Chem, 39 (2), 263-71
PubMed 8432015

Publications 1992

Odegaard OR, Lindahl AK, Try K, Kvalheim G, Sørbø JH (1992)
Recurrent venous thrombosis during warfarin treatment related to acquired protein S deficiency
Thromb Res, 66 (6), 729-34
DOI 10.1016/0049-3848(92)90048-f, PubMed 1519231

Ogniben E, Hohaus S, Kvalheim G, Dörken B, Haas R (1992)
Successful autologous transplantation of immunomagnetic bead purged bone marrow in non-Hodgkin's lymphoma
Prog Clin Biol Res, 377, 189-95
PubMed 1438415

Rusten L, Kvaløy SO, Jakobsen E, Kvalheim G, Abrahamsen AF, Høiby EA, Sandven P, Lassen J, Bruu AL (1992)
[Infection problems in the leukopenia phase after autologous bone marrow transplantation]
Tidsskr Nor Laegeforen, 112 (13), 1723-6
PubMed 1509434

SMELAND EB, FUNDERUD S, KVALHEIM G, EGELAND T (1992)
EFFECTIVE ISOLATION OF HUMAN HEMATOPOIETIC PROGENITOR CELLS - A NEW METHOD FOR DETACHMENT OF IMMUNOMAGNETIC BEADS FROM POSITIVELY SELECTED CD34+ CELLS
INT J CELL CLONING, 10 1, 108-110
DOI 10.1002/stem.5530100735

Smeland EB, Funderud S, Kvalheim G, Gaudernack G, Rasmussen AM, Rusten L, Wang MY, Tindle RW, Blomhoff HK, Egeland T (1992)
Isolation and characterization of human hematopoietic progenitor cells: an effective method for positive selection of CD34+ cells
Leukemia, 6 (8), 845-52
PubMed 1379314

Straka C, Kröner C, Dörken B, Kvalheim G (1992)
Polymerase chain reaction monitoring shows a high efficacy of clinical immunomagnetic purging in patients with centroblastic-centrocytic non-Hodgkin's lymphoma
Blood, 80 (10), 2688-90
PubMed 1421385

Wang MY, Kvalheim G, Kvaløy S, Beiske K, Jakobsen E, Wijdenes J, Pihl A, Fodstad O (1992)
An effective immunomagnetic method for bone marrow purging in T cell malignancies
Bone Marrow Transplant, 9 (5), 319-23
PubMed 1617315

Publications 1991

Körbling M, Knauf W, Funderud S, Kvalheim G, Hunstein W (1991)
Autologous transplantation of an immunomagnetic bead purged marrow in patients with relapsed acute lymphoblastic leukemia
Haematologica, 76 Suppl 1, 29-36
PubMed 1650742

Publications 1990

Storm-Mathisen I, Glomstein A, Lie SO, Albrechtsen D, Monclair T, Kvalheim G, Jacobsen AB (1990)
[Autologous bone marrow transplantation in children--experience with neuroblastoma]
Tidsskr Nor Laegeforen, 110 (19), 2513-6
PubMed 2219008

Publications 1989

Kvalheim G (1989)
Immunomagnetic removal ex vivo of malignant B-cells from human bone marrow
The Norwegian Cancer Society, [Oslo], 1 b. (flere pag.)
BIBSYS 890346666

Kvalheim G, Fjeld JG, Pihl A, Funderud S, Ugelstad J, Fodstad O, Nustad K (1989)
Immunomagnetic removal of B-lymphoma cells using a novel mono-sized magnetizable polymer bead, M-280, in conjunction with primary IgM and IgG antibodies
Bone Marrow Transplant, 4 (5), 567-74
PubMed 2790334

Publications 1988

Fodstad O, Kvalheim G, Pihl A, Godal A, Funderud S (1988)
New indirect approach to the therapeutic use of immunotoxins
J Natl Cancer Inst, 80 (6), 439-43
DOI 10.1093/jnci/80.6.439, PubMed 3259265

KVALHEIM G, FODSTAD O, FUNDERUD S, KIESEL S, DORKEN B, NUSTAD K, PIHL A (1988)
IMMUNOMAGNETIC PURGING OF BETA-LYMPHOMA CELLS FROM BONE-MARROW
Bone Marrow Transplant., 3 1, 97

Kvalheim G, Funderud S, Kvaløy S, Gaudernack G, Beiske K, Jakobsen E, Jacobsen AB, Pihl A, Fodstad O (1988)
Successful clinical use of an anti-HLA-DR monoclonal antibody for autologous bone marrow transplantation
J Natl Cancer Inst, 80 (16), 1322-5
DOI 10.1093/jnci/80.16.1322, PubMed 3050139

Kvalheim G, Sørensen O, Fodstad O, Funderud S, Kiesel S, Dörken B, Nustad K, Jakobsen E, Ugelstad J, Pihl A (1988)
Immunomagnetic removal of B-lymphoma cells from human bone marrow: a procedure for clinical use
Bone Marrow Transplant, 3 (1), 31-41
PubMed 3048468

Oftung F, Mustafa AS, Shinnick TM, Houghten RA, Kvalheim G, Degre M, Lundin KE, Godal T (1988)
Epitopes of the Mycobacterium tuberculosis 65-kilodalton protein antigen as recognized by human T cells
J Immunol, 141 (8), 2749-54
PubMed 2459228

Tretli S, Kvalheim G, Thoresen S, Høst H (1988)
Survival of breast cancer patients diagnosed during pregnancy or lactation
Br J Cancer, 58 (3), 382-4
DOI 10.1038/bjc.1988.224, PubMed 3179191

UGELSTAD J, BERGE A, ELLINGSEN T, AUNE O, KILAAS L, NILSEN TN, SCHMID R, STENSTAD P, FUNDERUD S, KVALHEIM G, NUSTAD K, LEA T, VARTDAL F, DANIELSEN H (1988)
MONOSIZED MAGNETIC PARTICLES AND THEIR USE IN SELECTIVE CELL-SEPARATION
MAKROMOL CHEM-M SYMP, 17, 177-211
DOI 10.1002/masy.19880170113

Publications 1987

GRAHAMPOLE J, BAST R, KERSEY J, JANOSSY G, NADLER L, MARTIN P, KERNAN N, HAMILTON B, PHILIP T, KVALHEIM G, KEMSHEAD J, GEE A (1987)
ANTIBODY-MEDIATED METHODS - ALLOGRAFTS AND AUTOGRAFTS - DISCUSSION
Bone Marrow Transplant., 2 2, 99-103

Kiesel S, Haas R, Moldenhauer G, Kvalheim G, Pezzutto A, Dörken B (1987)
Removal of cells from a malignant B-cell line from bone marrow with immunomagnetic beads and with complement and immunoglobulin switch variant mediated cytolysis
Leuk Res, 11 (12), 1119-25
DOI 10.1016/0145-2126(87)90166-4, PubMed 3320581

Kvalheim G, Fodstad O, Pihl A, Nustad K, Pharo A, Ugelstad J, Funderud S (1987)
Elimination of B-lymphoma cells from human bone marrow: model experiments using monodisperse magnetic particles coated with primary monoclonal antibodies
Cancer Res, 47 (3), 846-51
PubMed 3492268

NUSTAD K, MICHAELSEN TE, KIERULF B, FJELD JG, KVALHEIM G, PIHL A, UGELSTAD J, FUNDERUD S (1987)
ANTIGEN-BINDING PROPERTIES OF ANTIBODIES COATED ON MAGNETIC POLYMER BEADS
Bone Marrow Transplant., 2 2, 81-83

VARTDAL F, ALBRECHTSEN D, RINGDEN O, KVALHEIM G, LEA T, BOSNES V, GAUDERNACK G, BRINCHMANN J, UGELSTAD J (1987)
IMMUNOMAGNETIC TREATMENT OF BONE-MARROW ALLOGRAFTS
Bone Marrow Transplant., 2 2, 94-98

Vartdal F, Kvalheim G, Lea TE, Bosnes V, Gaudernack G, Ugelstad J, Albrechtsen D (1987)
Depletion of T lymphocytes from human bone marrow. Use of magnetic monosized polymer microspheres coated with T-lymphocyte-specific monoclonal antibodies
Transplantation, 43 (3), 366-71
DOI 10.1097/00007890-198703000-00010, PubMed 3103274

Publications 1986

Mustafa AS, Kvalheim G, Degre M, Godal T (1986)
Mycobacterium bovis BCG-induced human T-cell clones from BCG-vaccinated healthy subjects: antigen specificity and lymphokine production
Infect Immun, 53 (3), 491-7
DOI 10.1128/iai.53.3.491-497.1986, PubMed 2427449

Publications 1985

Kvalheim G, Gundersen S, Hager B, Fodstad O (1985)
Intra-arterial infusion of mitomycin C in treatment of breast cancer: occurrence of skin necrosis in irradiated patients
Radiother Oncol, 4 (2), 127-32
DOI 10.1016/s0167-8140(85)80099-2, PubMed 3934716

Ueland PM, Kvalheim G, Lønning PE, Kvinnsland S (1985)
Determination of warfarin in human plasma by high performance liquid chromatography and photodiode array detector
Ther Drug Monit, 7 (3), 329-35
DOI 10.1097/00007691-198507030-00018, PubMed 4049474

Publications 1984

Fodstad O, Kvalheim G, Godal A, Lotsberg J, Aamdal S, Høst H, Pihl A (1984)
Phase I study of the plant protein ricin
Cancer Res, 44 (2), 862-5
PubMed 6692385