Xavier Tekpli
Position: Post doc/Researcher
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Publications 2016

Tekpli X, Skaug V, Bæra R, Phillips DH, Haugen A, Mollerup S (2016)
Estrogen receptor expression and gene promoter methylation in non-small cell lung cancer - a short report
Cell Oncol (Dordr), 39 (6), 583-589
PubMed 27572263

Tekpli X, Urbanucci A, Hashim A, Vågbø CB, Lyle R, Kringen MK, Staff AC, Dybedal I, Mills IG, Klungland A, Staerk J (2016)
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
Epigenetics Chromatin, 9, 21
PubMed 27252783

Publications 2015

Hardonnière K, Huc L, Podechard N, Fernier M, Tekpli X, Gallais I, Sergent O, Lagadic-Gossmann D (2015)
Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential
Toxicol In Vitro, 29 (7), 1597-608
PubMed 26086121

Publications 2013

Dendelé B, Tekpli X, Hardonnière K, Holme JA, Debure L, Catheline D, Arlt VM, Nagy E, Phillips DH, Ovrebø S, Mollerup S, Poët M, Chevanne M, Rioux V, Dimanche-Boitrel MT, Sergent O, Lagadic-Gossmann D (2013)
Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway
Chem Biol Interact, 207, 41-51
PubMed 24246761

Publications 2012

Tekpli X, Holme JA, Sergent O, Lagadic-Gossmann D (2012)
Role for membrane remodeling in cell death: implication for health and disease
Toxicology, 304, 141-57
PubMed 23287390

Tekpli X, Huc L, Sergent O, Dendelé B, Dimanche-Boitrel MT, Holme JA, Lagadic-Gossmann D (2012)
NHE-1 relocation outside cholesterol-rich membrane microdomains is associated with its benzo[a]pyrene-related apoptotic function
Cell Physiol Biochem, 29 (5-6), 657-66
PubMed 22613966

Tekpli X, Landvik NE, Anmarkud KH, Skaug V, Haugen A, Zienolddiny S (2012)
DNA methylation at promoter regions of interleukin 1B, interleukin 6, and interleukin 8 in non-small cell lung cancer
Cancer Immunol Immunother, 62 (2), 337-45
PubMed 22923190

Tekpli X, Landvik NE, Skaug V, Gulsvik A, Haugen A, Zienolddiny S (2012)
Functional effect of polymorphisms in 15q25 locus on CHRNA5 mRNA, bulky DNA adducts and TP53 mutations
Int J Cancer, 132 (8), 1811-20
PubMed 23011884

Tekpli X, Zienolddiny S, Skaug V, Stangeland L, Haugen A, Mollerup S (2012)
DNA methylation of the CYP1A1 enhancer is associated with smoking-induced genetic alterations in human lung
Int J Cancer, 131 (7), 1509-16
PubMed 22213191

Publications 2011

Dendelé B, Tekpli X, Sergent O, Dimanche-Boitrel MT, Holme JA, Huc L, Lagadic-Gossmann D (2011)
Identification of the couple GSK3α/c-Myc as a new regulator of hexokinase II in benzo[a]pyrene-induced apoptosis
Toxicol In Vitro, 26 (1), 94-101
PubMed 22100782

Tekpli X, Holme JA, Sergent O, Lagadic-Gossmann D (2011)
Importance of plasma membrane dynamics in chemical-induced carcinogenesis
Recent Pat Anticancer Drug Discov, 6 (3), 347-53
PubMed 21756246

Publications 2010

Rebillard A, Jouan-Lanhouet S, Jouan E, Legembre P, Pizon M, Sergent O, Gilot D, Tekpli X, Lagadic-Gossmann D, Dimanche-Boitrel MT (2010)
Cisplatin-induced apoptosis involves a Fas-ROCK-ezrin-dependent actin remodelling in human colon cancer cells
Eur J Cancer, 46 (8), 1445-55
PubMed 20202822

Publications 2009

Asare N, Tekpli X, Rissel M, Solhaug A, Landvik N, Lecureur V, Podechard N, Brunborg G, Låg M, Lagadic-Gossmann D, Holme JA (2009)
Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells
Mutagenesis, 24 (6), 481-93
PubMed 19703935

Beauchamp E, Tekpli X, Marteil G, Lagadic-Gossmann D, Legrand P, Rioux V (2009)
N-Myristoylation targets dihydroceramide Delta4-desaturase 1 to mitochondria: partial involvement in the apoptotic effect of myristic acid
Biochimie, 91 (11-12), 1411-9
PubMed 19647031

Tekpli X, Rissel M, Huc L, Catheline D, Sergent O, Rioux V, Legrand P, Holme JA, Dimanche-Boitrel MT, Lagadic-Gossmann D (2009)
Membrane remodeling, an early event in benzo[a]pyrene-induced apoptosis
Toxicol Appl Pharmacol, 243 (1), 68-76
PubMed 19931295

Publications 2008

Asare N, Landvik NE, Lagadic-Gossmann D, Rissel M, Tekpli X, Ask K, Låg M, Holme JA (2008)
1-Nitropyrene (1-NP) induces apoptosis and apparently a non-apoptotic programmed cell death (paraptosis) in Hepa1c1c7 cells
Toxicol Appl Pharmacol, 230 (2), 175-86
PubMed 18417179

Gorria M, Tekpli X, Rissel M, Sergent O, Huc L, Landvik N, Fardel O, Dimanche-Boitrel MT, Holme JA, Lagadic-Gossmann D (2008)
A new lactoferrin- and iron-dependent lysosomal death pathway is induced by benzo[a]pyrene in hepatic epithelial cells
Toxicol Appl Pharmacol, 228 (2), 212-24
PubMed 18255115

Lacroix J, Poët M, Huc L, Morello V, Djerbi N, Ragno M, Rissel M, Tekpli X, Gounon P, Lagadic-Gossmann D, Counillon L (2008)
Kinetic analysis of the regulation of the Na+/H+ exchanger NHE-1 by osmotic shocks
Biochemistry, 47 (51), 13674-85
PubMed 19035652

Nourissat P, Travert M, Chevanne M, Tekpli X, Rebillard A, Le Moigne-Müller G, Rissel M, Cillard J, Dimanche-Boitrel MT, Lagadic-Gossmann D, Sergent O (2008)
Ethanol induces oxidative stress in primary rat hepatocytes through the early involvement of lipid raft clustering
Hepatology, 47 (1), 59-70
PubMed 18038449

Tekpli X, Huc L, Lacroix J, Rissel M, Poët M, Noël J, Dimanche-Boitrel MT, Counillon L, Lagadic-Gossmann D (2008)
Regulation of Na+/H+ exchanger 1 allosteric balance by its localization in cholesterol- and caveolin-rich membrane microdomains
J Cell Physiol, 216 (1), 207-20
PubMed 18264982

Publications 2007

Holme JA, Gorria M, Arlt VM, Ovrebø S, Solhaug A, Tekpli X, Landvik NE, Huc L, Fardel O, Lagadic-Gossmann D (2007)
Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells
Chem Biol Interact, 167 (1), 41-55
PubMed 17289009

Huc L, Tekpli X, Holme JA, Rissel M, Solhaug A, Gardyn C, Le Moigne G, Gorria M, Dimanche-Boitrel MT, Lagadic-Gossmann D (2007)
c-Jun NH2-terminal kinase-related Na+/H+ exchanger isoform 1 activation controls hexokinase II expression in benzo(a)pyrene-induced apoptosis
Cancer Res, 67 (4), 1696-705
PubMed 17308111

Rebillard A, Tekpli X, Meurette O, Sergent O, LeMoigne-Muller G, Vernhet L, Gorria M, Chevanne M, Christmann M, Kaina B, Counillon L, Gulbins E, Lagadic-Gossmann D, Dimanche-Boitrel MT (2007)
Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in human colon cancer cells
Cancer Res, 67 (16), 7865-74
PubMed 17699793

Publications 2006

Gorria M, Tekpli X, Sergent O, Huc L, Gaboriau F, Rissel M, Chevanne M, Dimanche-Boitrel MT, Lagadic-Gossmann D (2006)
Membrane fluidity changes are associated with benzo[a]pyrene-induced apoptosis in F258 cells: protection by exogenous cholesterol
Ann N Y Acad Sci, 1090, 108-12
PubMed 17384252

Huc L, Rissel M, Solhaug A, Tekpli X, Gorria M, Torriglia A, Holme JA, Dimanche-Boitrel MT, Lagadic-Gossmann D (2006)
Multiple apoptotic pathways induced by p53-dependent acidification in benzo[a]pyrene-exposed hepatic F258 cells
J Cell Physiol, 208 (3), 527-37
PubMed 16688778