Publications Department. of Tumor Biology

Publications published since 1971 from OUS - Department of Tumor Biology

1375 publications found (only first 1000 shown)

Publications 2024

1. Cavanaugh D, Urbanucci A, Mohamed NE, Tewari AK, Figueiro M, Kyprianou N (2024)
   Link between circadian rhythm and benign prostatic hyperplasia (BPH)/lower urinary tract symptoms (LUTS)
   Prostate, 84 (5), 417-425
   DOI 10.1002/pros.24656, PubMed 38193363
2. Foote JB, Mattox TE, Keeton AB, Chen X, Smith FT, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, Ganji PN, Maxuitenko Y, Valiyaveettil J, Carstens JL, Buchsbaum DJ, Yang J, Zhou G, Nurmemmedov E, Babic I, Gaponenko V et al. (2024)
   A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer
   bioRxiv
   DOI 10.1101/2023.05.17.541233, PubMed 38328254
3. Guldvik IJ, Ramberg H, Kristensen G, Røder A, Mills IG, Lilleby W, Taskén KA (2024)
   Systemic interrogation of immune-oncology-related proteins in patients with locally advanced prostate cancer undergoing androgen deprivation and intensity-modulated radiotherapy
   World J Urol, 42 (1), 95
   DOI 10.1007/s00345-024-04787-8, PubMed 38386171
4. Heinrich MC, Jones RL, George S, Gelderblom H, Schöffski P, von Mehren M, Zalcberg JR, Kang YK, Razak AA, Trent J, Attia S, Le Cesne A, Siontis BL, Goldstein D, Boye K, Sanchez C, Steeghs N, Rutkowski P, Druta M, Serrano C, Somaiah N, Chi P, Reichmann W, Sprott K, Achour H et al. (2024)
   Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial
   Nat Med, 30 (2), 498-506
   DOI 10.1038/s41591-023-02734-5, PubMed 38182785
5. Istvan P, Birkeland E, Avershina E, Kværner AS, Bemanian V, Pardini B, Tarallo S, de Vos WM, Rognes T, Berstad P, Rounge TB (2024)
   Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
   Nat Commun, 15 (1), 1791
   DOI 10.1038/s41467-024-46033-0, PubMed 38424056
6. Kandathil SA, Akhondi A, Kadletz-Wanke L, Heiduschka G, Engedal N, Brkic FF (2024)
   The dual role of autophagy in HPV-positive head and neck squamous cell carcinoma: a systematic review
   J Cancer Res Clin Oncol, 150 (2), 56
   DOI 10.1007/s00432-023-05514-3, PubMed 38291202
7. Kotsopoulos J, Gronwald J, Huzarski T, Møller P, Pal T, McCuaig JM, Singer CF, Karlan BY, Aeilts A, Eng C, Eisen A, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Neuhausen SL, Zakalik D, Cybulski C, Metcalfe K, Olopade OI, Sun P, Lubinski J, Narod SA, Hereditary Breast Cancer Clinical Study Group (2024)
   Bilateral Oophorectomy and All-Cause Mortality in Women With BRCA1 and BRCA2 Sequence Variations
   JAMA Oncol, 10 (4), 484-492
   DOI 10.1001/jamaoncol.2023.6937, PubMed 38421677
8. Lubinski J, Kotsopoulos J, Moller P, Pal T, Eisen A, Peck L, Karlan BY, Aeilts A, Eng C, Bordeleau L, Foulkes WD, Tung N, Couch FJ, Fruscio R, Ramon Y Cajal T, Singer CF, Neuhausen SL, Zakalik D, Cybulski C, Gronwald J, Huzarski T, Stempa K, Dungan J, Cullinane C, Olopade OI et al. (2024)
   MRI Surveillance and Breast Cancer Mortality in Women With BRCA1 and BRCA2 Sequence Variations
   JAMA Oncol, 10 (4), 493-499
   DOI 10.1001/jamaoncol.2023.6944, PubMed 38421676
9. Nikolski M, Hovig E, Al-Shahrour F, Blomberg N, Scollen S, Valencia A, Saunders G (2024)
   Roadmap for a European cancer data management and precision medicine infrastructure
   Nat Cancer, 5 (3), 367-372
   DOI 10.1038/s43018-023-00717-6, PubMed 38321342
10. Patrick-Brown TDJH, Bourner J, Kali S, Trøseid M, Yazdanpanah Y, Olliaro P, Olsen IC (2024)
    Experiences and challenges with the new European Clinical Trials Regulation
    Trials, 25 (1), 3
    DOI 10.1186/s13063-023-07869-x, PubMed 38167484
11. Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Chèneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A (2024)
    JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles
    Nucleic Acids Res, 52 (D1), D174-D182
    DOI 10.1093/nar/gkad1059, PubMed 37962376
12. Sveen A, Johannessen B, Klokkerud SM, Kraggerud SM, Meza-Zepeda LA, Bjørnslett M, Bischof K, Myklebost O, Taskén K, Skotheim RI, Dørum A, Davidson B, Lothe RA (2024)
    Evolutionary mode and timing of dissemination of high-grade serous carcinomas
    JCI Insight, 9 (3)
    DOI 10.1172/jci.insight.170423, PubMed 38175731
13. Torices L, Nunes-Xavier CE, Mingo J, Luna S, Erramuzpe A, Cortés JM, Pulido R (2024)
    Induction of Translational Readthrough on Protein Tyrosine Phosphatases Targeted by Premature Termination Codon Mutations in Human Disease
    Methods Mol Biol, 2743, 1-19
    DOI 10.1007/978-1-0716-3569-8_1, PubMed 38147205
14. Valsalakumari R, Pandya AD, Prasmickaite L, Kvalvaag A, Myrann AG, Åslund AKO, Kjos MS, Fontecha-Cuenca C, Haroon HB, Ribeiro ARS, Horejs-Hoeck J, Moghimi SM, Mørch Ý, Skotland T, Sandvig K, Mælandsmo GM, Iversen TG (2024)
    Preclinical Efficacy of Cabazitaxel Loaded Poly(2-alkyl cyanoacrylate) Nanoparticle Variants
    Int J Nanomedicine, 19, 3009-3029
    DOI 10.2147/IJN.S450283, PubMed 38562610
15. Zhou Y, Ray PS, Zhu J, Stein F, Rettel M, Sekaran T, Sahadevan S, Perez-Perri JI, Roth EK, Myklebost O, Meza-Zepeda LA, von Deimling A, Fu C, Brosig AN, Boye K, Nathrath M, Blattmann C, Lehner B, Hentze MW, Kulozik AE (2024)
    Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma
    Nat Commun, 15 (1), 2810
    DOI 10.1038/s41467-024-47031-y, PubMed 38561347

Publications 2023

1. Akdeniz BC, Mattingsdal M, Dominguez-Valentin M, Frei O, Shadrin A, Puustusmaa M, Saar R, Sõber S, Møller P, Andreassen OA, Padrik P, Hovig E (2023)
   A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
   Cancers (Basel), 15 (16)
   DOI 10.3390/cancers15164124, PubMed 37627152
2. Anzar I, Malone B, Samarakoon P, Vardaxis I, Simovski B, Fontenelle H, Meza-Zepeda LA, Stratford R, Keung EZ, Burgess M, Tawbi HA, Myklebost O, Clancy T (2023)
   The interplay between neoantigens and immune cells in sarcomas treated with checkpoint inhibition
   Front Immunol, 14, 1226445
   DOI 10.3389/fimmu.2023.1226445, PubMed 37799721
3. Arjona-Sanchez A, Martinez-López A, Moreno-Montilla MT, Mulsow J, Lozano-Lominchar P, Martínez-Torres B, Rau B, Canbay E, Sommariva A, Milione M, Deraco M, Sgarbura O, Torgunrud A, Kepenekian V, Carr NJ, Hoorens A, Delhorme JB, Wernert R, Goere D, Martin-Roman L, Cosyns S, Flatmark K, Davidson B, Khellaf L, Pereira-Perez F et al. (2023)
   External multicentre validation of pseudomyxoma peritonei PSOGI-Ki67 classification
   Eur J Surg Oncol, 49 (8), 1481-1488
   DOI 10.1016/j.ejso.2023.03.206, PubMed 36935222
4. Ballinger ML, Pattnaik S, Mundra PA, Zaheed M, Rath E, Priestley P, Baber J, Ray-Coquard I, Isambert N, Causeret S, van der Graaf WTA, Puri A, Duffaud F, Le Cesne A, Seddon B, Chandrasekar C, Schiffman JD, Brohl AS, James PA, Kurtz JE, Penel N, Myklebost O, Meza-Zepeda LA, Pickett H, Kansara M et al. (2023)
   Heritable defects in telomere and mitotic function selectively predispose to sarcomas
   Science, 379 (6629), 253-260
   DOI 10.1126/science.abj4784, PubMed 36656928
5. Billingham L, Brown L, Framke T, Greystoke A, Hovig E, Mathur S, Page P, Pean E, Barjesteh van Waalwijk van Doorn-Khosrovani S, Vonk R, Wissink S, Zander H, Plummer R (2023)
   Histology independent drug development - Is this the future for cancer drugs?
   Cancer Treat Rev, 123, 102674
   DOI 10.1016/j.ctrv.2023.102674, PubMed 38176220
6. Bucher-Johannessen C, Birkeland EE, Vinberg E, Bemanian V, Hoff G, Berstad P, Rounge TB (2023)
   Long-term follow-up of colorectal cancer screening attendees identifies differences in Phascolarctobacterium spp. using 16S rRNA and metagenome sequencing
   Front Oncol, 13, 1183039
   DOI 10.3389/fonc.2023.1183039, PubMed 37182146
7. Dominguez-Valentin M, Haupt S, Seppälä TT, Sampson JR, Sunde L, Bernstein I, Jenkins MA, Engel C, Aretz S, Nielsen M, Capella G, Balaguer F, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Della Valle A et al. (2023)
   Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
   EClinicalMedicine, 58, 101909
   DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409
8. Doutel D, Davidson B, Nitschke Pettersen IK, Torgunrud A (2023)
   Molecular characteristics of low-grade serous carcinoma in effusions
   Cytopathology, 34 (2), 99-105
   DOI 10.1111/cyt.13207, PubMed 36609991
9. Ellingsen EB, O'Day S, Mezheyeuski A, Gromadka A, Clancy T, Kristedja TS, Milhem M, Zakharia Y (2023)
   Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
   Clin Cancer Res, 29 (16), 3026-3036
   DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632
10. Figlioli G, Billaud A, Wang Q, Bolla MK, Dennis J, Lush M, Kvist A, Adank MA, Ahearn TU, Antonenkova NN, Auvinen P, Behrens S, Bermisheva M, Bogdanova NV, Bojesen SE, Bonanni B, Brüning T, Camp NJ, Campbell A, Castelao JE, Cessna MH, Nbcs Collaborators, Czene K, Devilee P, Dörk T et al. (2023)
    Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases
    Cancers (Basel), 15 (13)
    DOI 10.3390/cancers15133313, PubMed 37444426
11. Getu AA, Tigabu A, Zhou M, Lu J, Fodstad Ø, Tan M (2023)
    New frontiers in immune checkpoint B7-H3 (CD276) research and drug development
    Mol Cancer, 22 (1), 43
    DOI 10.1186/s12943-023-01751-9, PubMed 36859240
12. Ghannoum S, Fantini D, Zahoor M, Reiterer V, Phuyal S, Leoncio Netto W, Sørensen Ø, Iyer A, Sengupta D, Prasmickaite L, Mælandsmo GM, Köhn-Luque A, Farhan H (2023)
    A combined experimental-computational approach uncovers a role for the Golgi matrix protein Giantin in breast cancer progression
    PLoS Comput Biol, 19 (4), e1010995
    DOI 10.1371/journal.pcbi.1010995, PubMed 37068117
13. Hanes R, Ayuda-Durán P, Rønneberg L, Nakken S, Hovig E, Zucknick M, Enserink JM (2023)
    screenwerk: a modular tool for the design and analysis of drug combination screens
    Bioinformatics, 39 (1)
    DOI 10.1093/bioinformatics/btac840, PubMed 36573326
14. Haugen MH, von der Lippe Gythfeldt H, Egeland EV, Svartdal Normann L, Pandya AD, Vedin LL, Juell S, Tenstad E, Øy GF, Kristian A, Marangoni E, Sørlie T, Steffensen K, Maelandsmo GM, Engebraaten O (2023)
    Liver X receptors induce antiproliferative effects in basal-like breast cancer
    Mol Oncol, 17 (10), 2041-2055
    DOI 10.1002/1878-0261.13476, PubMed 37341140
15. Hodan R, Rodgers-Fouche L, Chittenden A, Dominguez-Valentin M, Ferriss J, Gima L, Hamnvik OR, Idos GE, Kline K, Koeller DR, Long JM, McKenna D, Muller C, Thoman M, Wintner A, Bedrick BS, Collaborative Group of the Americas on Inherited Gastrointestinal Cancer (2023)
    Cancer surveillance for transgender and gender diverse patients with Lynch syndrome: a practice resource of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    Fam Cancer, 22 (4), 437-448
    DOI 10.1007/s10689-023-00341-4, PubMed 37341816
16. Holme B, Bjørnerud B, Pedersen NM, de la Ballina LR, Wesche J, Haugsten EM (2023)
    Automated tracking of cell migration in phase contrast images with CellTraxx
    Sci Rep, 13 (1), 22982
    DOI 10.1038/s41598-023-50227-9, PubMed 38151514
17. Hyldbakk A, Fleten KG, Snipstad S, Åslund AKO, Davies CL, Flatmark K, Mørch Y (2023)
    Intraperitoneal administration of cabazitaxel-loaded nanoparticles in peritoneal metastasis models
    Nanomedicine, 48, 102656
    DOI 10.1016/j.nano.2023.102656, PubMed 36646195
18. Ibrahim EIK, Ellingsen EB, Mangsbo SM, Friberg LE (2023)
    Bridging responses to a human telomerase reverse transcriptase-based peptide cancer vaccine candidate in a mechanism-based model
    Int Immunopharmacol, 126, 111225
    DOI 10.1016/j.intimp.2023.111225, PubMed 37988911
19. Ito I, Yousef AM, Dickson PN, Naini ZA, White MG, Fleten KG, Flatmark K, Fournier KF, Fowlkes NW, Shen JP (2023)
    Antitumor activity of intraperitoneal paclitaxel in orthotopic patient-derived xenograft models of mucinous appendiceal adenocarcinoma
    bioRxiv
    DOI 10.1101/2023.02.01.526672, PubMed 36993681
20. Kalyanasundaram S, Lefol Y, Gundersen S, Rognes T, Alsøe L, Nilsen HL, Hovig E, Sandve GK, Domanska D (2023)
    hGSuite HyperBrowser: A web-based toolkit for hierarchical metadata-informed analysis of genomic tracks
    PLoS One, 18 (7), e0286330
    DOI 10.1371/journal.pone.0286330, PubMed 37467208
21. Knutsen E, Das Sajib S, Fiskaa T, Lorens J, Gudjonsson T, Mælandsmo GM, Johansen SD, Seternes OM, Perander M (2023)
    Identification of a core EMT signature that separates basal-like breast cancers into partial- and post-EMT subtypes
    Front Oncol, 13, 1249895
    DOI 10.3389/fonc.2023.1249895, PubMed 38111531
22. Lamsal A, Andersen SB, Johansson I, Vietri M, Bokil AA, Kurganovs NJ, Rylander F, Bjørkøy G, Pettersen K, Giambelluca MS (2023)
    Opposite and dynamic regulation of the interferon response in metastatic and non-metastatic breast cancer
    Cell Commun Signal, 21 (1), 50
    DOI 10.1186/s12964-023-01062-y, PubMed 36882786
23. López JI, Hogan MF, Sutton B, Church SE, Angulo JC, Nunes-Xavier CE (2023)
    Distinct spatial landscapes in clear-cell renal cell carcinoma as revealed by whole transcriptome analysis
    Immunooncol Technol, 21, 100690
    DOI 10.1016/j.iotech.2023.100690, PubMed 38292905
24. Mo T, Brandal SHB, Geier OM, Engebråten O, Nilsen LB, Kristensen VN, Hole KH, Hompland T, Fleischer T, Seierstad T (2023)
    MRI Assessment of Changes in Tumor Vascularization during Neoadjuvant Anti-Angiogenic Treatment in Locally Advanced Breast Cancer Patients
    Cancers (Basel), 15 (18)
    DOI 10.3390/cancers15184662, PubMed 37760629
25. Mraz KA, Hodan R, Rodgers-Fouche L, Arora S, Balaguer F, Guillem JG, Jeter JM, Kanth P, Li D, Liska D, Melson J, Perez K, Ricker C, Shirts BH, Vilar E, Katona BW, Dominguez-Valentin M (2023)
    Current chemoprevention approaches in Lynch syndrome and Familial adenomatous polyposis: a global clinical practice survey
    Front Oncol, 13, 1141810
    DOI 10.3389/fonc.2023.1141810, PubMed 37293588
26. Møller P, Seppälä TT, Ahadova A, Crosbie EJ, Holinski-Feder E, Scott R, Haupt S, Möslein G, Winship I, Broeke SWB, Kohut KE, Ryan N, Bauerfeind P, Thomas LE, Evans DG, Aretz S, Sijmons RH, Half E, Heinimann K, Horisberger K, Monahan K, Engel C, Cavestro GM, Fruscio R, Abu-Freha N et al. (2023)
    Dominantly inherited micro-satellite instable cancer - the four Lynch syndromes - an EHTG, PLSD position statement
    Hered Cancer Clin Pract, 21 (1), 19
    DOI 10.1186/s13053-023-00263-3, PubMed 37821984
27. Nakken S, Gundersen S, Bernal FLM, Polychronopoulos D, Hovig E, Wesche J (2023)
    Comprehensive interrogation of gene lists from genome-scale cancer screens with oncoEnrichR
    Int J Cancer, 153 (10), 1819-1828
    DOI 10.1002/ijc.34666, PubMed 37551617
28. Namløs HM, Khelik K, Nakken S, Vodák D, Hovig E, Myklebost O, Boye K, Meza-Zepeda LA (2023)
    Chromosomal instability and a deregulated cell cycle are intrinsic features of high-risk gastrointestinal stromal tumours with a metastatic potential
    Mol Oncol, 17 (11), 2432-2450
    DOI 10.1002/1878-0261.13514, PubMed 37622176
29. Normann LS, Haugen MH, Hongisto V, Aure MR, Leivonen SK, Kristensen VN, Tahiri A, Engebraaten O, Sahlberg KK, Mælandsmo GM (2023)
    High-throughput screen in vitro identifies dasatinib as a candidate for combinatorial treatment with HER2-targeting drugs in breast cancer
    PLoS One, 18 (1), e0280507
    DOI 10.1371/journal.pone.0280507, PubMed 36706086
30. Nunes-Xavier CE, Emaldi M, Mingo J, Øyjord T, Mælandsmo GM, Fodstad Ø, Errarte P, Larrinaga G, Llarena R, López JI, Pulido R (2023)
    The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
    Sci Rep, 13 (1), 7339
    DOI 10.1038/s41598-023-34087-x, PubMed 37147361
31. Nunes-Xavier CE, Emaldi M, Mingo J, Øyjord T, Mælandsmo GM, Fodstad Ø, Errarte P, Larrinaga G, Llarena R, López JI, Pulido R (2023)
    Author Correction: The expression pattern of pyruvate dehydrogenase kinases predicts prognosis and correlates with immune exhaustion in clear cell renal cell carcinoma
    Sci Rep, 13 (1), 9186
    DOI 10.1038/s41598-023-36328-5, PubMed 37280349
32. Nygaard V, Ree AH, Dagenborg VJ, Børresen-Dale AL, Edwin B, Fretland ÅA, Grzyb K, Haugen MH, Mælandsmo GM, Flatmark K (2023)
    A PRRX1 Signature Identifies TIM-3 and VISTA as Potential Immune Checkpoint Targets in a Subgroup of Microsatellite Stable Colorectal Cancer Liver Metastases
    Cancer Res Commun, 3 (2), 235-244
    DOI 10.1158/2767-9764.CRC-22-0295, PubMed 36968142
33. Parry MA, Grist E, Mendes L, Dutey-Magni P, Sachdeva A, Brawley C, Murphy L, Proudfoot J, Lall S, Liu Y, Friedrich S, Ismail M, Hoyle A, Ali A, Haran A, Wingate A, Zakka L, Wetterskog D, Amos CL, Atako NB, Wang V, Rush HL, Jones RJ, Leung H, Cross WR et al. (2023)
    Clinical testing of transcriptome-wide expression profiles in high-risk localized and metastatic prostate cancer starting androgen deprivation therapy: an ancillary study of the STAMPEDE abiraterone Phase 3 trial
    Res Sq
    DOI 10.21203/rs.3.rs-2488586/v1, PubMed 36798177
34. Patrick-Brown TDJH, Mohamed F, Thrower A, Torgunrud A, Cosyns S, Canbay E, Villeneuve L, Flatmark K, Brandl A (2023)
    Determining a minimum data set for reporting clinical and radiologic data for pseudomyxoma peritonei
    Pleura Peritoneum, 8 (1), 1-9
    DOI 10.1515/pp-2022-0200, PubMed 37020469
35. Pettersen S, Øy GF, Egeland EV, Juell S, Engebråten O, Mælandsmo GM, Prasmickaite L (2023)
    Breast cancer patient-derived explant cultures recapitulate in vivo drug responses
    Front Oncol, 13, 1040665
    DOI 10.3389/fonc.2023.1040665, PubMed 36910663
36. Połeć A, Ekstrøm PO, Fougner C, Sørlie T, Norum JH (2023)
    Rapid assessment of 3-dimensional intra-tumor heterogeneity through cycling temperature capillary electrophoresis
    BMC Res Notes, 16 (1), 167
    DOI 10.1186/s13104-023-06437-5, PubMed 37568187
37. Pulido R, Nunes-Xavier CE (2023)
    Editorial: Cell and Developmental Signalling in Neuroblastoma
    Front Cell Dev Biol, 10, 1126352
    DOI 10.3389/fcell.2022.1126352, PubMed 36684434
38. Rodgers-Fouche L, Arora S, Ricker C, Li D, Farooqi M, Balaguer F, Dominguez-Valentin M, Guillem JG, Kanth P, Liska D, Melson J, Mraz KA, Shirts BH, Vilar E, Katona BW, Hodan R (2023)
    Exploring Stakeholders' Perspectives on Implementing Universal Germline Testing for Colorectal Cancer: Findings From a Clinical Practice Survey
    JCO Precis Oncol, 7, e2300440
    DOI 10.1200/PO.23.00440, PubMed 37897815
39. Rodríguez-Varela R, Moore KHS, Ebenesersdóttir SS, Kilinc GM, Kjellström A, Papmehl-Dufay L, Alfsdotter C, Berglund B, Alrawi L, Kashuba N, Sobrado V, Lagerholm VK, Gilbert E, Cavalleri GL, Hovig E, Kockum I, Olsson T, Alfredsson L, Hansen TF, Werge T, Munters AR, Bernhardsson C, Skar B, Christophersen A, Turner-Walker G et al. (2023)
    The genetic history of Scandinavia from the Roman Iron Age to the present
    Cell, 186 (1), 32-46.e19
    DOI 10.1016/j.cell.2022.11.024, PubMed 36608656
40. Severson TM, Zhu Y, Prekovic S, Schuurman K, Nguyen HM, Brown LG, Hakkola S, Kim Y, Kneppers J, Linder S, Stelloo S, Lieftink C, van der Heijden M, Nykter M, van der Noort V, Sanders J, Morris B, Jenster G, van Leenders GJ, Pomerantz M, Freedman ML, Beijersbergen RL, Urbanucci A, Wessels L, Corey E et al. (2023)
    Enhancer profiling identifies epigenetic markers of endocrine resistance and reveals therapeutic options for metastatic castration-resistant prostate cancer patients
    medRxiv
    DOI 10.1101/2023.02.24.23286403, PubMed 36865297
41. Solbakken AM, Flatmark K (2023)
    ASO Author Reflections: Navigation-Assisted Surgery for Locally Advanced and Recurrent Rectal Cancer: The NAVI-LARRC Trial
    Ann Surg Oncol, 30 (12), 7633-7634
    DOI 10.1245/s10434-023-14058-2, PubMed 37573284
42. Solbakken AM, Sellevold S, Spasojevic M, Julsrud L, Emblemsvåg HL, Reims HM, Sørensen O, Thorgersen EB, Fauske L, Ågren JSM, Brennhovd B, Ryder T, Larsen SG, Flatmark K (2023)
    Navigation-Assisted Surgery for Locally Advanced Primary and Recurrent Rectal Cancer
    Ann Surg Oncol, 30 (12), 7602-7611
    DOI 10.1245/s10434-023-13964-9, PubMed 37481493
43. Tamargo-Gómez I, Martínez-García GG, Suárez MF, Mayoral P, Bretones G, Astudillo A, Prieto-Lloret J, Sveen C, Fueyo A, Engedal N, López-Otín C, Mariño G (2023)
    Analysis of ATG4C function in vivo
    Autophagy, 19 (11), 2912-2933
    DOI 10.1080/15548627.2023.2234799, PubMed 37459465
44. Thorgersen EB, Solbakken AM, Strøm TK, Goscinski M, Spasojevic M, Larsen SG, Flatmark K (2023)
    Short-term results after robot-assisted surgery for primary rectal cancers requiring beyond total mesorectal excision in multiple compartments
    Scand J Surg, 113 (1), 3-12
    DOI 10.1177/14574969231200654, PubMed 37787437
45. Torices L, Nunes-Xavier CE, López JI, Pulido R (2023)
    Novel anti-PTEN C2 domain monoclonal antibodies to analyse the expression and function of PTEN isoform variants
    PLoS One, 18 (8), e0289369
    DOI 10.1371/journal.pone.0289369, PubMed 37527256

Publications 2022

1. Ahadova A, Witt J, Haupt S, Gallon R, Hüneburg R, Nattermann J, Ten Broeke S, Bohaumilitzky L, Hernandez-Sanchez A, Santibanez-Koref M, Jackson MS, Ahtiainen M, Pylvänäinen K, Andini K, Grolmusz VK, Möslein G, Dominguez-Valentin M, Møller P, Fürst D, Sijmons R, Borthwick GM, Burn J, Mecklin JP, Heuveline V, von Knebel Doeberitz M et al. (2022)
   Is HLA type a possible cancer risk modifier in Lynch syndrome?
   Int J Cancer, 152 (10), 2024-2031
   DOI 10.1002/ijc.34312, PubMed 36214792
2. Alaña L, Nunes-Xavier CE, Zaldumbide L, Martin-Guerrero I, Mosteiro L, Alba-Pavón P, Villate O, García-Obregón S, González-García H, Herraiz R, Astigarraga I, Pulido R, García-Ariza M (2022)
   Identification and Functional Analysis of a Novel CTNNB1 Mutation in Pediatric Medulloblastoma
   Cancers (Basel), 14 (2)
   DOI 10.3390/cancers14020421, PubMed 35053583
3. Alver TN, Heintz KM, Hovig E, Bøe SL (2022)
   Cooperative induction of receptor tyrosine kinases contributes to adaptive MAPK drug resistance in melanoma through the PI3K pathway
   Cancer Rep (Hoboken), 6 (2), e1736
   DOI 10.1002/cnr2.1736, PubMed 36251678
4. Ambrosini M, Del Re M, Manca P, Hendifar A, Drilon A, Harada G, Ree AH, Klempner S, Mælandsmo GM, Flatmark K, Russnes HG, Cleary JM, Singh H, Sottotetti E, Martinetti A, Randon G, Sartore-Bianchi A, Capone I, Milione M, Di Bartolomeo M, Pietrantonio F (2022)
   ALK Inhibitors in Patients With ALK Fusion-Positive GI Cancers: An International Data Set and a Molecular Case Series
   JCO Precis Oncol, 6 (1), e2200015
   DOI 10.1200/PO.22.00015, PubMed 35476549
5. Bjørklund SS, Aure MR, Häkkinen J, Vallon-Christersson J, Kumar S, Evensen KB, Fleischer T, Tost J, OSBREAC, Sahlberg KK, Mathelier A, Bhanot G, Ganesan S, Tekpli X, Kristensen VN (2022)
   Subtype and cell type specific expression of lncRNAs provide insight into breast cancer
   Commun Biol, 5 (1), 834
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6. Cao S, Wang JR, Ji S, Yang P, Dai Y, Guo S, Montierth MD, Shen JP, Zhao X, Chen J, Lee JJ, Guerrero PA, Spetsieris N, Engedal N, Taavitsainen S, Yu K, Livingstone J, Bhandari V, Hubert SM, Daw NC, Futreal PA, Efstathiou E, Lim B, Viale A, Zhang J et al. (2022)
   Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression
   Nat Biotechnol, 40 (11), 1624-1633
   DOI 10.1038/s41587-022-01342-x, PubMed 35697807
7. Cavestro GM, Mannucci A, Balaguer F, Hampel H, Kupfer SS, Repici A, Sartore-Bianchi A, Seppälä TT, Valentini V, Boland CR, Brand RE, Buffart TE, Burke CA, Caccialanza R, Cannizzaro R, Cascinu S, Cercek A, Crosbie EJ, Danese S, Dekker E, Daca-Alvarez M, Deni F, Dominguez-Valentin M, Eng C, Goel A et al. (2022)
   Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
   Clin Gastroenterol Hepatol, 21 (3), 581-603.e33
   DOI 10.1016/j.cgh.2022.12.006, PubMed 36549470
8. Dominguez-Valentin M, Sampson JR, Seppälä TT, Møller P (2022)
   Response to Chambuso et al
   Genet Med, 24 (5), 1151
   DOI 10.1016/j.gim.2022.01.005, PubMed 35216900
9. Ellingsen EB, Bounova G, Kerzeli I, Anzar I, Simnica D, Aamdal E, Guren T, Clancy T, Mezheyeuski A, Inderberg EM, Mangsbo SM, Binder M, Hovig E, Gaudernack G (2022)
   Characterization of the T cell receptor repertoire and melanoma tumor microenvironment upon combined treatment with ipilimumab and hTERT vaccination
   J Transl Med, 20 (1), 419
   DOI 10.1186/s12967-022-03624-z, PubMed 36089578
10. Ellingsen EB, Aamdal E, Guren T, Lilleby W, Brunsvig PF, Mangsbo SM, Aamdal S, Hovig E, Mensali N, Gaudernack G, Inderberg EM (2022)
    Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials
    J Immunother Cancer, 10 (5)
    DOI 10.1136/jitc-2021-004345, PubMed 35613827
11. Emaldi M, Nunes-Xavier CE (2022)
    B7-H4 Immune Checkpoint Protein Affects Viability and Targeted Therapy of Renal Cancer Cells
    Cells, 11 (9)
    DOI 10.3390/cells11091448, PubMed 35563753
12. Engedal N, Proikas-Cezanne T, Albertini MC, Žerovnik E, Lane JD (2022)
    Transautophagy: Research and Translation of Autophagy Knowledge 2020
    Oxid Med Cell Longev, 2022, 9792132
    DOI 10.1155/2022/9792132, PubMed 35340207
13. Engedal N, Sønstevold T, Beese CJ, Selladurai S, Melcher T, Simensen JE, Frankel LB, Urbanucci A, Torgersen ML (2022)
    Measuring Autophagic Cargo Flux with Keima-Based Probes
    Methods Mol Biol, 2445, 99-115
    DOI 10.1007/978-1-0716-2071-7_7, PubMed 34972988
14. Fiorito E, Szybowska P, Haugsten EM, Kostas M, Øy GF, Wiedlocha A, Singh S, Nakken S, Mælandsmo GM, Fletcher JA, Meza-Zepeda LA, Wesche J (2022)
    Strategies to inhibit FGFR4 V550L-driven rhabdomyosarcoma
    Br J Cancer, 127 (11), 1939-1953
    DOI 10.1038/s41416-022-01973-6, PubMed 36097178
15. Fleten KG, Hyldbakk A, Einen C, Benjakul S, Strand BL, Davies CL, Mørch Ý, Flatmark K (2022)
    Alginate Microsphere Encapsulation of Drug-Loaded Nanoparticles: A Novel Strategy for Intraperitoneal Drug Delivery
    Mar Drugs, 20 (12)
    DOI 10.3390/md20120744, PubMed 36547891
16. Flobak Å, Skånland SS, Hovig E, Taskén K, Russnes HG (2022)
    Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
    Trends Pharmacol Sci, 43 (11), 973-985
    DOI 10.1016/j.tips.2022.08.009, PubMed 36163057
17. Fromm B, Høye E, Domanska D, Zhong X, Aparicio-Puerta E, Ovchinnikov V, Umu SU, Chabot PJ, Kang W, Aslanzadeh M, Tarbier M, Mármol-Sánchez E, Urgese G, Johansen M, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2022)
    MirGeneDB 2.1: toward a complete sampling of all major animal phyla
    Nucleic Acids Res, 50 (D1), D204-D210
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18. Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2022)
    Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
    J Control Release, 349, 1
    DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388
19. Georgiesh T, Aggerholm-Pedersen N, Schöffski P, Zhang Y, Napolitano A, Bovée JVMG, Hjelle Å, Tang G, Spalek M, Nannini M, Swanson D, Baad-Hansen T, Sciot R, Hesla AC, Huang P, Dorleijn D, Haugland HK, Lacambra M, Skoczylas J, Pantaleo MA, Haas RL, Meza-Zepeda LA, Haller F, Czarnecka AM, Loong H et al. (2022)
    Validation of a novel risk score to predict early and late recurrence in solitary fibrous tumour
    Br J Cancer, 127 (10), 1793-1798
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20. Giliberto M, Santana LM, Holien T, Misund K, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Coward E, Waage A, Taskén K, Skånland SS (2022)
    Mutational analysis and protein profiling predict drug sensitivity in multiple myeloma cell lines
    Front Oncol, 12, 1040730
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21. Gopalakrishnan S, Ebenesersdóttir SS, Lundstrøm IKC, Turner-Walker G, Moore KHS, Luisi P, Margaryan A, Martin MD, Ellegaard MR, Magnússon ÓÞ, Sigurðsson Á, Snorradóttir S, Magnúsdóttir DN, Laffoon JE, van Dorp L, Liu X, Moltke I, Ávila-Arcos MC, Schraiber JG, Rasmussen S, Juan D, Gelabert P, de-Dios T, Fotakis AK, Iraeta-Orbegozo M et al. (2022)
    The population genomic legacy of the second plague pandemic
    Curr Biol, 32 (21), 4743-4751.e6
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22. Gorunova L, Boye K, Panagopoulos I, Berner JM, Bjerkehagen B, Hompland I, Lobmaier I, Hølmebakk T, Hveem TS, Heim S, Micci F (2022)
    Cytogenetic and molecular analyses of 291 gastrointestinal stromal tumors: site-specific cytogenetic evolution as evidence of pathogenetic heterogeneity
    Oncotarget, 13, 508-517
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23. Guldvik IJ, Braadland PR, Sivanesan S, Ramberg H, Kristensen G, Tennstedt P, Røder A, Schlomm T, Berge V, Eri LM, Lilleby W, Mills IG, Taskén KA (2022)
    Low Blood Levels of LRG1 Before Radical Prostatectomy Identify Patients with High Risk of Progression to Castration-resistant Prostate Cancer
    Eur Urol Open Sci, 45, 68-75
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24. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 225
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25. Helland Å, Russnes HG, Fagereng GL, Al-Shibli K, Andersson Y, Berg T, Bjørge L, Blix E, Bjerkehagen B, Brabrand S, Cameron MG, Dalhaug A, Dietzel D, Dønnem T, Enerly E, Flobak Å, Fluge S, Gilje B, Gjertsen BT, Grønberg BH, Grønås K, Guren T, Hamre H, Haug Å, Heinrich D et al. (2022)
    Correction to: Improving public cancer care by implementing precision medicine in Norway: IMPRESS-Norway
    J Transl Med, 20 (1), 317
    DOI 10.1186/s12967-022-03518-0, PubMed 35841045
26. Hodan R, Rodgers-Fouche L, Arora S, Dominguez-Valentin M, Kanth P, Katona BW, Mraz KA, Roberts ME, Vilar E, Soto-Azghani CM, Brand RE, Esplin ED, Perez K (2022)
    Patterns of germline and somatic testing after universal tumor screening for Lynch syndrome: A clinical practice survey of active members of the Collaborative Group of the Americas on Inherited Gastrointestinal Cancer
    J Genet Couns, 31 (4), 949-955
    DOI 10.1002/jgc4.1567, PubMed 35218578
27. Høye E, Dagenborg VJ, Torgunrud A, Lund-Andersen C, Fretland ÅA, Lorenz S, Edwin B, Hovig E, Fromm B, Inderberg EM, Greiff V, Ree AH, Flatmark K (2022)
    T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
    Gigascience, 12
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28. Høye E, Fromm B, Böttger PHM, Domanska D, Torgunrud A, Lund-Andersen C, Abrahamsen TW, Fretland ÅA, Dagenborg VJ, Lorenz S, Edwin B, Hovig E, Flatmark K (2022)
    A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer
    NAR Cancer, 4 (1), zcab051
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29. Li H, Engel C, Hoya M, Peterlongo P, Yannoukakos D, Livraghi L, Radice P, Thomassen M, Hansen TVO, Gerdes AM, Nielsen HR, Caputo SM, Zambelli A, Borg A, Solano A, Thomas A, Parsons MT, Antoniou AC, Leslie G, Yang X, Chenevix-Trench G, Caldes T, Kwong A, Pedersen IS, Lautrup CK et al. (2022)
    Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
    Genet Med, 24 (10), 2208
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30. Meltzer S, Negård A, Bakke KM, Hamre HM, Kersten C, Hofsli E, Guren MG, Sorbye H, Flatmark K, Ree AH (2022)
    Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
    Br J Cancer, 127 (12), 2227-2233
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31. Metcalfe KA, Gronwald J, Tung NM, McCuaig JM, Eisen A, Elser C, Foulkes WD, Neuhausen SL, Senter L, Moller P, Bordeleau L, Fruscio R, Velsher L, Zakalik D, Olopade OI, Eng C, Pal T, Cullinane CA, Couch FJ, Kotsopoulos J, Sun P, Lubinski J, Narod SA (2022)
    The risks of cancer in older women with BRCA pathogenic variants: How far have we come?
    Cancer, 129 (6), 901-907
    DOI 10.1002/cncr.34615, PubMed 36571512
32. Misund K, Hofste Op Bruinink D, Coward E, Hoogenboezem RM, Rustad EH, Sanders MA, Rye M, Sponaas AM, van der Holt B, Zweegman S, Hovig E, Meza-Zepeda LA, Sundan A, Myklebost O, Sonneveld P, Waage A (2022)
    Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence
    Leukemia, 36 (7), 1887-1897
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33. Mo T, Brandal SHB, Köhn-Luque A, Engebraaten O, Kristensen VN, Fleischer T, Hompland T, Seierstad T (2022)
    Quantification of Tumor Hypoxia through Unsupervised Modelling of Consumption and Supply Hypoxia MR Imaging in Breast Cancer
    Cancers (Basel), 14 (5)
    DOI 10.3390/cancers14051326, PubMed 35267636
34. Møller P (2022)
    The Prospective Lynch Syndrome Database: background, design, main results and complete MySQL code
    Hered Cancer Clin Pract, 20 (1), 37
    DOI 10.1186/s13053-022-00243-z, PubMed 36411472
35. Møller P, Evans DG (2022)
    Inherited Cancer Genetic Epidemiology to Improve Precision Medicine
    J Clin Med, 11 (3)
    DOI 10.3390/jcm11030879, PubMed 35160330
36. Møller P, Seppälä T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L, Bernstein I, Engel C, Aretz S, Nielsen M, Capella G, Evans DG, Burn J, Holinski-Feder E, Bertario L, Bonanni B, Lindblom A, Levi Z, Macrae F, Winship I, Plazzer JP, Sijmons R, Laghi L, Valle AD, Heinimann K et al. (2022)
    Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
    Hered Cancer Clin Pract, 20 (1), 36
    DOI 10.1186/s13053-022-00241-1, PubMed 36182917
37. Namløs HM, Skårn M, Ahmed D, Grad I, Andresen K, Kresse SH, Munthe E, Serra M, Scotlandi K, Llombart-Bosch A, Myklebost O, Lind GE, Meza-Zepeda LA (2022)
    miR-486-5p expression is regulated by DNA methylation in osteosarcoma
    BMC Genomics, 23 (1), 142
    DOI 10.1186/s12864-022-08346-6, PubMed 35172717
38. Ng MYW, Charsou C, Lapao A, Singh S, Trachsel-Moncho L, Schultz SW, Nakken S, Munson MJ, Simonsen A (2022)
    The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
    Nat Commun, 13 (1), 6283
    DOI 10.1038/s41467-022-33933-2, PubMed 36270994
39. Normann LS, Haugen MH, Aure MR, Kristensen VN, Mælandsmo GM, Sahlberg KK (2022)
    miR-101-5p Acts as a Tumor Suppressor in HER2-Positive Breast Cancer Cells and Improves Targeted Therapy
    Breast Cancer (Dove Med Press), 14, 25-39
    DOI 10.2147/BCTT.S338404, PubMed 35256859
40. Nunes-Xavier CE, Emaldi M, Guldvik IJ, Ramberg H, Taskén KA, Mælandsmo GM, Fodstad Ø, Llarena R, Pulido R, López JI (2022)
    Correlation of expression of Major Vault Protein with androgen receptor and immune checkpoint protein B7-H3, and with poor prognosis in prostate cancer
    Pathol Res Pract, 241, 154243
    DOI 10.1016/j.prp.2022.154243, PubMed 36481650
41. Nunes-Xavier CE, Mingo J, Emaldi M, Flem-Karlsen K, Mælandsmo GM, Fodstad Ø, Llarena R, López JI, Pulido R (2022)
    Heterogeneous Expression and Subcellular Localization of Pyruvate Dehydrogenase Complex in Prostate Cancer
    Front Oncol, 12, 873516
    DOI 10.3389/fonc.2022.873516, PubMed 35692804
42. Nyakas M, Fleten KG, Haugen MH, Engedal N, Sveen C, Farstad IN, Flørenes VA, Prasmickaite L, Mælandsmo GM, Seip K (2022)
    AXL inhibition improves BRAF-targeted treatment in melanoma
    Sci Rep, 12 (1), 5076
    DOI 10.1038/s41598-022-09078-z, PubMed 35332208
43. Pinto R, Hauge T, Jeanmougin M, Pharo HD, Kresse SH, Honne H, Winge SB, Five MB, Kumar T, Mala T, Hauge T, Johnson E, Lind GE (2022)
    Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus
    Clin Epigenetics, 14 (1), 77
    DOI 10.1186/s13148-022-01287-7, PubMed 35701814
44. Pulido R, Nunes-Xavier CE (2022)
    Hopes on immunotherapy targeting B7-H3 in neuroblastoma
    Transl Oncol, 27, 101580
    DOI 10.1016/j.tranon.2022.101580, PubMed 36327699
45. Ree AH, Mælandsmo GM, Flatmark K, Russnes HG, Gómez Castañeda M, Aas E (2022)
    Cost-effectiveness of molecularly matched off-label therapies for end-stage cancer - the MetAction precision medicine study
    Acta Oncol, 61 (8), 955-962
    DOI 10.1080/0284186X.2022.2098053, PubMed 35943168
46. Sivanesan S, Taskén KA, Grytli HH (2022)
    Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
    JAMA Netw Open, 5 (1), e2145230
    DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602
47. Sohlberg E, Pfefferle A, Heggernes Ask E, Tschan-Plessl A, Jacobs B, Netskar H, Lorenz S, Kanaya M, Kosugi-Kanaya M, Meinke S, Mörtberg A, Höglund P, Sundin M, Carlsson G, Palmblad J, Malmberg KJ (2022)
    Perturbed NK-cell homeostasis associated with disease severity in chronic neutropenia
    Blood, 139 (5), 704-716
    DOI 10.1182/blood.2021013233, PubMed 34699594
48. Stacchiotti S, Dürr HR, Schaefer IM, Woertler K, Haas R, Trama A, Caraceni A, Bajpai J, Baldi GG, Bernthal N, Blay JY, Boye K, Broto JM, Chen WT, Dei Tos PA, Desai J, Emhofer S, Eriksson M, Gronchi A, Gelderblom H, Hardes J, Hartmann W, Healey J, Italiano A, Jones RL et al. (2022)
    Best clinical management of tenosynovial giant cell tumour (TGCT): A consensus paper from the community of experts
    Cancer Treat Rev, 112, 102491
    DOI 10.1016/j.ctrv.2022.102491, PubMed 36502615
49. Søreng K, Pankiv S, Bergsmark C, Haugsten EM, Dahl AK, de la Ballina LR, Yamamoto A, Lystad AH, Simonsen A (2022)
    ALFY localizes to early endosomes and cellular protrusions to facilitate directional cell migration
    J Cell Sci, 135 (4)
    DOI 10.1242/jcs.259138, PubMed 35099014
50. Taskén K, Russnes HEG, Aas E, Bjørge L, Blix ES, CONNECT Public–Private Partnership Consortium, Enerly E, Fagereng GL, Flobak Å, Gilje B, Gjertsen BT, Guren TK, Heix J, Hovig E, Hovland R, InPreD-Norway and National Molecular Tumor Board Consortium, IMPRESS-Norway Consortium, Lønning PE, Meza-Zepeda LA, Mæhle PM, Nilsen HL, Thoresen SØ, Widerberg K, Smeland S, Helland Å (2022)
    A national precision cancer medicine implementation initiative for Norway
    Nat Med, 28 (5), 885-887
    DOI 10.1038/s41591-022-01777-4, PubMed 35513529
51. Tellez-Gabriel M, Tekpli X, Reine TM, Hegge B, Nielsen SR, Chen M, Moi L, Normann LS, Busund LR, Calin GA, Mælandsmo GM, Perander M, Theocharis AD, Kolset SO, Knutsen E (2022)
    Serglycin Is Involved in TGF-β Induced Epithelial-Mesenchymal Transition and Is Highly Expressed by Immune Cells in Breast Cancer Tissue
    Front Oncol, 12, 868868
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52. Thomassen M, Mesman RLS, Hansen TVO, Menendez M, Rossing M, Esteban-Sánchez A, Tudini E, Törngren T, Parsons MT, Pedersen IS, Teo SH, Kruse TA, Møller P, Borg Å, Jensen UB, Christensen LL, Singer CF, Muhr D, Santamarina M, Brandao R, Andresen BS, Feng BJ, Canson D, Richardson ME, Karam R et al. (2022)
    Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach
    Hum Mutat, 43 (12), 1921-1944
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53. Torices L, Mingo J, Rodríguez-Escudero I, Fernández-Acero T, Luna S, Nunes-Xavier CE, López JI, Mercadillo F, Currás M, Urioste M, Molina M, Cid VJ, Pulido R (2022)
    Functional analysis of PTEN variants of unknown significance from PHTS patients unveils complex patterns of PTEN biological activity in disease
    Eur J Hum Genet, 31 (5), 568-577
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54. Vaccaro CA, Soarez J, Dominguez-Valentin M, Pavicic WH (2022)
    Editorial: Advances in genetics and molecular diagnosis in colorectal, stomach, and pancreatic cancer
    Front Oncol, 12, 1104671
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55. Venizelos A, Engebrethsen C, Deng W, Geisler J, Geisler S, Iversen GT, Aas T, Aase HS, Seyedzadeh M, Steinskog ES, Myklebost O, Nakken S, Vodak D, Hovig E, Meza-Zepeda LA, Lønning PE, Knappskog S, Eikesdal HP (2022)
    Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy
    Genome Med, 14 (1), 86
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56. Xia YY, Gronwald J, Karlan B, Lubinski J, McCuaig JM, Brooks J, Moller P, Eisen A, Sun S, Senter L, Bordeleau L, Neuhausen SL, Singer CF, Tung N, Foulkes WD, Sun P, Narod SA, Kotsopoulos J, Hereditary Ovarian Cancer Clinical Study Group (2022)
    Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation
    Gynecol Oncol, 164 (3), 514-521
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57. Zavaleta E, Solis N, Palacios MI, Zevallos-Escobar LE, Corales EV, Bazo-Alvarez JC, Dominguez-Barrera C, Campos A, Wernhoff P, Ekstrøm PO, Møller P, Visnovska T, Hovig E, Balazar-Palacios J, Alvarez-Valenzuela K, Nakken S, Dominguez-Valentin M (2022)
    Genetic Characterization in High-Risk Individuals from a Low-Resource City of Peru
    Cancers (Basel), 14 (22)
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Publications 2021

1. Andersson Y, Fleten KG, Abrahamsen TW, Reed W, Davidson B, Flatmark K (2021)
   Anti-Angiogenic Treatment in Pseudomyxoma Peritonei-Still a Strong Preclinical Rationale
   Cancers (Basel), 13 (11)
   DOI 10.3390/cancers13112819, PubMed 34198773
2. Barkovskaya A, Goodwin CM, Seip K, Hilmarsdottir B, Pettersen S, Stalnecker C, Engebraaten O, Briem E, Der CJ, Moestue SA, Gudjonsson T, Maelandsmo GM, Prasmickaite L (2021)
   Detection of phenotype-specific therapeutic vulnerabilities in breast cells using a CRISPR loss-of-function screen
   Mol Oncol, 15 (8), 2026-2045
   DOI 10.1002/1878-0261.12951, PubMed 33759347
3. Baxter JS, Johnson N, Tomczyk K, Gillespie A, Maguire S, Brough R, Fachal L, Michailidou K, Bolla MK, Wang Q, Dennis J, Ahearn TU, Andrulis IL, Anton-Culver H, Antonenkova NN, Arndt V, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE et al. (2021)
   Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
   Am J Hum Genet, 108 (7), 1190-1203
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    DOI 10.1007/s10549-020-06072-9, PubMed 33423179
66. Sveen A, Johannessen B, Eilertsen IA, Røsok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjørnbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
    The expressed mutational landscape of microsatellite stable colorectal cancers
    Genome Med, 13 (1), 142
    DOI 10.1186/s13073-021-00955-2, PubMed 34470667
67. Svendsen HA, Meling TR, Nygaard V, Waagene S, Russnes H, Juell S, Rogne SG, Pahnke J, Helseth E, Fodstad Ø, Maelandsmo GM (2021)
    Novel human melanoma brain metastasis models in athymic nude fox1^nu mice: Site-specific metastasis patterns reflecting their clinical origin
    Cancer Med, 10 (23), 8604-8613
    DOI 10.1002/cam4.4334, PubMed 34612023
68. Szybowska P, Kostas M, Wesche J, Haugsten EM, Wiedlocha A (2021)
    Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling
    Cells, 10 (6)
    DOI 10.3390/cells10061342, PubMed 34071546
69. Sønstevold T, Engedal N, Torgersen ML (2021)
    Perturbation of Cellular Redox Homeostasis Dictates Divergent Effects of Polybutyl Cyanoacrylate (PBCA) Nanoparticles on Autophagy
    Cells, 10 (12)
    DOI 10.3390/cells10123432, PubMed 34943939
70. Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2021)
    Correction to: Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of highgrade pseudomyxoma peritonei
    Clin Exp Metastasis, 38 (2), 253
    DOI 10.1007/s10585-021-10084-0, PubMed 33649933
71. Tamhane T, Njenga RW, Burden RE, Bueth H, Maelandsmo GM, Haugen MH, Scott CJ, Brix K (2021)
    Trafficking of Full-Length and N-Terminally Truncated Cathepsin B in Human Colorectal Carcinoma Cells
    Appl. Sci.-Basel, 11 (24), 11936
    DOI 10.3390/app112411936
72. Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
    Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
    Ann Surg Oncol, 28 (9), 5252-5262
    DOI 10.1245/s10434-021-10022-0, PubMed 34019185
73. Thorgersen EB, Flatmark K (2021)
    ASO Author Reflections: The Peritoneum is an Active Immunological Compartment
    Ann Surg Oncol, 28 (9), 5263-5264
    DOI 10.1245/s10434-021-10036-8, PubMed 33939046
74. Torices L, de Las Heras J, Arango-Lasprilla JC, Cortés JM, Nunes-Xavier CE, Pulido R (2021)
    MMADHC premature termination codons in the pathogenesis of cobalamin D disorder: Potential of translational readthrough reconstitution
    Mol Genet Metab Rep, 26, 100710
    DOI 10.1016/j.ymgmr.2021.100710, PubMed 33552904
75. Taavitsainen S, Engedal N, Cao S, Handle F, Erickson A, Prekovic S, Wetterskog D, Tolonen T, Vuorinen EM, Kiviaho A, Nätkin R, Häkkinen T, Devlies W, Henttinen S, Kaarijärvi R, Lahnalampi M, Kaljunen H, Nowakowska K, Syvälä H, Bläuer M, Cremaschi P, Claessens F, Visakorpi T, Tammela TLJ, Murtola T et al. (2021)
    Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
    Nat Commun, 12 (1), 5307
    DOI 10.1038/s41467-021-25624-1, PubMed 34489465
76. Valsalakumari R, Yadava SK, Szwed M, Pandya AD, Mælandsmo GM, Torgersen ML, Iversen TG, Skotland T, Sandvig K, Giri J (2021)
    Mechanism of cellular uptake and cytotoxicity of paclitaxel loaded lipid nanocapsules in breast cancer cells
    Int J Pharm, 597, 120217
    DOI 10.1016/j.ijpharm.2021.120217, PubMed 33486035
77. van der Zanden TM, Mooij MG, Vet NJ, Neubert A, Rascher W, Lagler FB, Male C, Grytli H, Halvorsen T, de Hoog M, de Wildt SN (2021)
    Benefit-Risk Assessment of Off-Label Drug Use in Children: The Bravo Framework
    Clin Pharmacol Ther, 110 (4), 952-965
    DOI 10.1002/cpt.2336, PubMed 34145575
78. Vikan AK, Kostas M, Haugsten EM, Selbo PK, Wesche J (2021)
    Efficacy and Selectivity of FGF2-Saporin Cytosolically Delivered by PCI in Cells Overexpressing FGFR1
    Cells, 10 (6)
    DOI 10.3390/cells10061476, PubMed 34204611
79. Wang N, Bai D, Kristiansen E, Deng R, Zhang S (2021)
    AKIP1 promotes tumor progression by cancer-related pathways and predicts prognosis in tongue squamous cell carcinoma
    Am J Transl Res, 13 (11), 12338-12351
    PubMed 34956456
80. Wiedlocha A, Haugsten EM, Zakrzewska M (2021)
    Roles of the FGF-FGFR Signaling System in Cancer Development and Inflammation
    Cells, 10 (9)
    DOI 10.3390/cells10092231, PubMed 34571880
81. Aamdal E, Inderberg EM, Ellingsen EB, Rasch W, Brunsvig PF, Aamdal S, Heintz KM, Vodák D, Nakken S, Hovig E, Nyakas M, Guren TK, Gaudernack G (2021)
    Combining a Universal Telomerase Based Cancer Vaccine With Ipilimumab in Patients With Metastatic Melanoma - Five-Year Follow Up of a Phase I/IIa Trial
    Front Immunol, 12, 663865
    DOI 10.3389/fimmu.2021.663865, PubMed 34046035

Publications 2020

1. Aghayan DL, Kazaryan AM, Dagenborg VJ, Røsok BI, Fagerland MW, Waaler Bjørnelv GM, Kristiansen R, Flatmark K, Fretland ÅA, Edwin B, OSLO-COMET Survival Study Collaborators (2020)
   Long-Term Oncologic Outcomes After Laparoscopic Versus Open Resection for Colorectal Liver Metastases : A Randomized Trial
   Ann Intern Med, 174 (2), 175-182
   DOI 10.7326/M20-4011, PubMed 33197213
2. Ahadova A, Seppälä TT, Engel C, Gallon R, Burn J, Holinski-Feder E, Steinke-Lange V, Möslein G, Nielsen M, Ten Broeke SW, Laghi L, Dominguez-Valentin M, Capella G, Macrae F, Scott R, Hüneburg R, Nattermann J, Hoffmeister M, Brenner H, Bläker H, von Knebel Doeberitz M, Sampson JR, Vasen H, Mecklin JP, Møller P et al. (2020)
   The "unnatural" history of colorectal cancer in Lynch syndrome: Lessons from colonoscopy surveillance
   Int J Cancer, 148 (4), 800-811
   DOI 10.1002/ijc.33224, PubMed 32683684
3. Álvarez K, Orellana P, De la Fuente M, Canales T, Pinto E, Heine C, Solar B, Hurtado C, Møller P, Kronberg U, Zarate AJ, Dominguez-Valentin M, López-Köstner F (2020)
   Spectrum and Frequency of Tumors, Cancer Risk and Survival in Chilean Families with Lynch Syndrome: Experience of the Implementation of a Registry
   J Clin Med, 9 (6)
   DOI 10.3390/jcm9061861, PubMed 32549215
4. Arstad C, Taskén K, Refinetti P, Axcrona U, Giercksky KE, Ekstrøm PO (2020)
   Somatic Mitochondrial DNA Point Mutations Used as Biomarkers to Demonstrate Genomic Heterogeneity in Primary Prostate Cancer
   Prostate Cancer, 2020, 7673684
   DOI 10.1155/2020/7673684, PubMed 32908706
5. Barkovskaya A, Seip K, Prasmickaite L, Mills IG, Moestue SA, Itkonen HM (2020)
   Inhibition of O-GlcNAc transferase activates tumor-suppressor gene expression in tamoxifen-resistant breast cancer cells
   Sci Rep, 10 (1), 16992
   DOI 10.1038/s41598-020-74083-z, PubMed 33046784
6. Chen B, Dragomir MP, Fabris L, Bayraktar R, Knutsen E, Liu X, Tang C, Li Y, Shimura T, Ivkovic TC, De Los Santos MC, Anfossi S, Shimizu M, Shah MY, Ling H, Shen P, Multani AS, Pardini B, Burks JK, Katayama H, Reineke LC, Huo L, Syed M, Song S, Ferracin M et al. (2020)
   The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling
   Gastroenterology, 159 (6), 2146-2162.e33
   DOI 10.1053/j.gastro.2020.08.018, PubMed 32805281
7. Dagenborg VJ, Marshall SE, Yaqub S, Grzyb K, Boye K, Lund-Iversen M, Høye E, Berstad AE, Fretland ÅA, Edwin B, Ree AH, Flatmark K (2020)
   Neoadjuvant chemotherapy is associated with a transient increase of intratumoral T-cell density in microsatellite stable colorectal liver metastases
   Cancer Biol Ther, 21 (5), 432-440
   DOI 10.1080/15384047.2020.1721252, PubMed 32098573
8. De Las Heras J, Diez I, Jimenez-Marin A, Cabrera A, Ramos-Usuga D, Diaz-Fernandez MV, Torices L, Nunes-Xavier CE, Pulido R, Arango-Lasprilla JC, Cortes JM (2020)
   Brain Circuit Alterations and Cognitive Disability in Late-Onset Cobalamin D Disorder
   J Clin Med, 9 (4)
   DOI 10.3390/jcm9040990, PubMed 32252256
9. Dillard P, Köksal H, Maggadottir SM, Winge-Main A, Pollmann S, Menard M, Myhre MR, Mælandsmo GM, Flørenes VA, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
   Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
   Mol Ther, 29 (3), 1199-1213
   DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301
10. Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2020)
    Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
    Genet Med, 23 (4), 705-712
    DOI 10.1038/s41436-020-01029-1, PubMed 33257847
11. Dominguez-Valentin M, Sampson JR, Møller P, Seppälä TT, PLSD Collaborators (2020)
    Analysis in the Prospective Lynch Syndrome Database identifies sarcoma as part of the Lynch syndrome tumor spectrum
    Int J Cancer, 148 (2), 512-513
    DOI 10.1002/ijc.33214, PubMed 32783184
12. Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2020)
    Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
    Genet Med, 22 (9), 1569
    DOI 10.1038/s41436-020-0892-4, PubMed 32690931
13. Dominguez-Valentin M, Seppälä TT, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W, Vangala D et al. (2020)
    Risk-Reducing Gynecological Surgery in Lynch Syndrome: Results of an International Survey from the Prospective Lynch Syndrome Database
    J Clin Med, 9 (7)
    DOI 10.3390/jcm9072290, PubMed 32708519
14. Flatmark K, Mohamed F (2020)
    ASO Author Reflections: Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method
    Ann Surg Oncol, 27 (Suppl 3), 771-772
    DOI 10.1245/s10434-020-08691-4, PubMed 32495284
15. Flem-Karlsen K, Fodstad Ø, Nunes-Xavier CE (2020)
    B7-H3 Immune Checkpoint Protein in Human Cancer
    Curr Med Chem, 27 (24), 4062-4086
    DOI 10.2174/0929867326666190517115515, PubMed 31099317
16. Flem-Karlsen K, Nyakas M, Farstad IN, McFadden E, Wernhoff P, Jacobsen KD, Flørenes VA, Mælandsmo GM (2020)
    Soluble AXL as a marker of disease progression and survival in melanoma
    PLoS One, 15 (1), e0227187
    DOI 10.1371/journal.pone.0227187, PubMed 31917795
17. Fleten KG, Lund-Andersen C, Waagene S, Abrahamsen TW, Mørch Y, Boye K, Torgunrud A, Flatmark K (2020)
    Experimental Treatment of Mucinous Peritoneal Metastases Using Patient-Derived Xenograft Models
    Transl Oncol, 13 (8), 100793
    DOI 10.1016/j.tranon.2020.100793, PubMed 32447231
18. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D132-D141
    DOI 10.1093/nar/gkz885, PubMed 31598695
19. Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
    MirGeneDB 2.0: the metazoan microRNA complement
    Nucleic Acids Res, 48 (D1), D1172
    DOI 10.1093/nar/gkz1016, PubMed 31642479
20. Georgiesh T, Boye K, Bjerkehagen B (2020)
    A novel risk score to predict early and late recurrence in solitary fibrous tumour
    Histopathology, 77 (1), 123-132
    DOI 10.1111/his.14078, PubMed 31991494
21. Guldvik IJ, Zuber V, Braadland PR, Grytli HH, Ramberg H, Lilleby W, Thiede B, Zucknick M, Saatcioglu F, Gislefoss R, Kvåle R, George A, Grönberg H, Wiklund F, Neal DE, Gnanapragasam VJ, Taskén KA, Mills IG (2020)
    Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification
    Eur Urol Open Sci, 21, 51-60
    DOI 10.1016/j.euros.2020.08.007, PubMed 34337468
22. Halvorsen AR, Haugen MH, Öjlert ÅK, Lund-Iversen M, Jørgensen L, Solberg S, Mælandsmo GM, Brustugun OT, Helland Å (2020)
    Protein Kinase C Isozymes Associated With Relapse Free Survival in Non-Small Cell Lung Cancer Patients
    Front Oncol, 10, 590755
    DOI 10.3389/fonc.2020.590755, PubMed 33324562
23. Hernández-Sandoval JA, Gutiérrez-Angulo M, Magaña-Torres MT, Alvizo-Rodríguez CR, Ramírez-Plascencia HHF, Flores-López BA, Valenzuela-Pérez JA, Peregrina-Sandoval J, Moreno-Ortiz JM, Domínguez-Valentín M, Ayala-Madrigal ML (2020)
    Prevalence of the BRAF p.v600e variant in patients with colorectal cancer from Mexico and its estimated frequency in Latin American and Caribbean populations
    J Investig Med, 68 (5), 985-991
    DOI 10.1136/jim-2020-001301, PubMed 32184228
24. Humbert M, Morán M, de la Cruz-Ojeda P, Muntané J, Wiedmer T, Apostolova N, McKenna SL, Velasco G, Balduini W, Eckhart L, Janji B, Sampaio-Marques B, Ludovico P, Žerovnik E, Langer R, Perren A, Engedal N, Tschan MP (2020)
    Assessing Autophagy in Archived Tissue or How to Capture Autophagic Flux from a Tissue Snapshot
    Biology (Basel), 9 (3)
    DOI 10.3390/biology9030059, PubMed 32245178
25. Itkonen HM, Poulose N, Steele RE, Martin SES, Levine ZG, Duveau DY, Carelli R, Singh R, Urbanucci A, Loda M, Thomas CJ, Mills IG, Walker S (2020)
    Inhibition of O-GlcNAc Transferase Renders Prostate Cancer Cells Dependent on CDK9
    Mol Cancer Res, 18 (10), 1512-1521
    DOI 10.1158/1541-7786.MCR-20-0339, PubMed 32611550
26. Knutsen E, Lellahi SM, Aure MR, Nord S, Fismen S, Larsen KB, Gabriel MT, Hedberg A, Bjørklund SS, Oslo Breast Cancer Research Consortium (OSBREAC), Bofin AM, Mælandsmo GM, Sørlie T, Mortensen ES, Perander M (2020)
    The expression of the long NEAT1_2 isoform is associated with human epidermal growth factor receptor 2-positive breast cancers
    Sci Rep, 10 (1), 1277
    DOI 10.1038/s41598-020-57759-4, PubMed 31992741
27. Kohvakka A, Sattari M, Shcherban A, Annala M, Urbanucci A, Kesseli J, Tammela TLJ, Kivinummi K, Latonen L, Nykter M, Visakorpi T (2020)
    AR and ERG drive the expression of prostate cancer specific long noncoding RNAs
    Oncogene, 39 (30), 5241-5251
    DOI 10.1038/s41388-020-1365-6, PubMed 32555329
28. Kotsopoulos J, Karlan B, Gronwald J, Hall E, Moller P, Tung N, Zakalik D, Foulkes WD, Rosen B, Neuhausen SL, Sun P, Lubinksi J, Narod SA (2020)
    Long-term outcomes following a diagnosis of ovarian cancer at the time of preventive oophorectomy among BRCA1 and BRCA2 mutation carriers
    Int J Gynecol Cancer, 30 (6), 825-830
    DOI 10.1136/ijgc-2019-001141, PubMed 32354794
29. Kramer I, Hooning MJ, Mavaddat N, Hauptmann M, Keeman R, Steyerberg EW, Giardiello D, Antoniou AC, Pharoah PDP, Canisius S, Abu-Ful Z, Andrulis IL, Anton-Culver H, Aronson KJ, Augustinsson A, Becher H, Beckmann MW, Behrens S, Benitez J, Bermisheva M, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Brauch H et al. (2020)
    Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk
    Am J Hum Genet, 107 (5), 837-848
    DOI 10.1016/j.ajhg.2020.09.001, PubMed 33022221
30. Lavelle TJ, Alver TN, Heintz KM, Wernhoff P, Nygaard V, Nakken S, Øy GF, Bøe SL, Urbanucci A, Hovig E (2020)
    Dysregulation of MITF Leads to Transformation in MC1R-Defective Melanocytes
    Cancers (Basel), 12 (7)
    DOI 10.3390/cancers12071719, PubMed 32605315
31. Lien VT, Kristiansen MK, Pettersen S, Haugen MH, Krauss S, Olberg DE, Waaler J, Klaveness J (2020)
    Correction: Towards dual inhibitors of the MET kinase and WNT signaling pathway; design, synthesis and biological evaluation
    RSC Adv, 10 (9), 4927
    DOI 10.1039/d0ra90007a, PubMed 35503286
32. Meltzer S, Bjørnetrø T, Lyckander LG, Flatmark K, Dueland S, Samiappan R, Johansen C, Kalanxhi E, Ree AH, Redalen KR (2020)
    Corrigendum to "Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer" [Transl Oncol 12 (8) (2019) 1038-1044]
    Transl Oncol, 13 (1), 122-124
    DOI 10.1016/j.tranon.2019.09.005, PubMed 31843135
33. Møller P (2020)
    The Prospective Lynch Syndrome Database reports enable evidence-based personal precision health care
    Hered Cancer Clin Pract, 18, 6
    DOI 10.1186/s13053-020-0138-0, PubMed 32190163
34. Møller P, Dominguez-Valentin M, Rødland EA, Hovig E (2020)
    Correction: Møller, P.; et al. Causes for Frequent Pathogenic BRCA1 Variants Include Low Penetrance in Fertile Ages, Recurrent De-Novo Mutations and Genetic Drift. Cancers 2019, 11, 132
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020410, PubMed 32050665
35. Møller P, Sampson J, Dominguez-Valentin M, Burn J, Sunde L, Möslein G, Mecklin JP, Seppälä T (2020)
    Letter to the Editor-Recent advances in Lynch syndrome
    Fam Cancer, 20 (2), 117-118
    DOI 10.1007/s10689-020-00200-6, PubMed 32770425
36. Olafsdottir EJ, Borg A, Jensen MB, Gerdes AM, Johansson ALV, Barkardottir RB, Johannsson OT, Ejlertsen B, Sønderstrup IMH, Hovig E, Lænkholm AV, Hansen TVO, Olafsdottir GH, Rossing M, Jonasson JG, Sigurdsson S, Loman N, Nilsson MP, Narod SA, Tryggvadottir L (2020)
    Breast cancer survival in Nordic BRCA2 mutation carriers-unconventional association with oestrogen receptor status
    Br J Cancer, 123 (11), 1608-1615
    DOI 10.1038/s41416-020-01056-4, PubMed 32939053
37. Pace M, Falappa M, Freschi A, Balzani E, Berteotti C, Lo Martire V, Kaveh F, Hovig E, Zoccoli G, Amici R, Cerri M, Urbanucci A, Tucci V (2020)
    Loss of Snord116 impacts lateral hypothalamus, sleep, and food-related behaviors
    JCI Insight, 5 (12)
    DOI 10.1172/jci.insight.137495, PubMed 32365348
38. Pandya AD, Øverbye A, Sahariah P, Gaware VS, Høgset H, Masson M, Høgset A, Mælandsmo GM, Skotland T, Sandvig K, Iversen TG (2020)
    Drug-Loaded Photosensitizer-Chitosan Nanoparticles for Combinatorial Chemo- and Photodynamic-Therapy of Cancer
    Biomacromolecules, 21 (4), 1489-1498
    DOI 10.1021/acs.biomac.0c00061, PubMed 32092254
39. Patrick-Brown TDJH, Carr NJ, Swanson DM, Larsen S, Mohamed F, Flatmark K (2020)
    Estimating the Prevalence of Pseudomyxoma Peritonei in Europe Using a Novel Statistical Method
    Ann Surg Oncol, 28 (1), 252-257
    DOI 10.1245/s10434-020-08655-8, PubMed 32488520
40. Piñero TA, Soukarieh O, Rolain M, Alvarez K, López-Köstner F, Torrezan GT, Carraro DM, De Oliveira Nascimento IL, Bomfim TF, Machado-Lopes TMB, Freitas JC, Toralles MB, Sandes KA, Rossi BM, Junior SA, Meira J, Dominguez-Valentin M, Møller P, Vaccaro CA, Martins A, Pavicic WH (2020)
    MLH1 intronic variants mapping to + 5 position of splice donor sites lead to deleterious effects on RNA splicing
    Fam Cancer, 19 (4), 323-336
    DOI 10.1007/s10689-020-00182-5, PubMed 32363481
41. Ree AH, Nygaard V, Boye K, Heinrich D, Dueland S, Bergheim IR, Johansen C, Beiske K, Negård A, Lund-Iversen M, Nygaard V, Hovig E, Nakken S, Nasser S, Julsrud L, Reisse CH, Ruud EA, Kristensen VN, Flørenes VA, Geitvik GA, Lingjærde OC, Børresen-Dale AL, Russnes HG, Mælandsmo GM, Flatmark K (2020)
    Molecularly matched therapy in the context of sensitivity, resistance, and safety; patient outcomes in end-stage cancer - the MetAction study
    Acta Oncol, 59 (7), 733-740
    DOI 10.1080/0284186X.2020.1742377, PubMed 32208873
42. Refinetti P, Morgenthaler S, Thilly WG, Arstad C, Ekstrøm PO (2020)
    Tracing of Human Tumor Cell Lineages by Mitochondrial Mutations
    Front Oncol, 10, 523860
    DOI 10.3389/fonc.2020.523860, PubMed 33344219
43. Saeednejad Zanjani L, Madjd Z, Axcrona U, Abolhasani M, Rasti A, Asgari M, Fodstad Ø, Andersson Y (2020)
    Cytoplasmic expression of B7-H3 and membranous EpCAM expression are associated with higher grade and survival outcomes in patients with clear cell renal cell carcinoma
    Ann Diagn Pathol, 46, 151483
    DOI 10.1016/j.anndiagpath.2020.151483, PubMed 32143173
44. Salgado D, Armean IM, Baudis M, Beltran S, Capella-Gutierrez S, Carvalho-Silva D, Dominguez Del Angel V, Dopazo J, Furlong LI, Gao B, Garcia L, Gerloff D, Gut I, Gyenesei A, Habermann N, Hancock JM, Hanauer M, Hovig E, Johansson LF, Keane T, Korbel J, Lauer KB, Laurie S, Leskošek B, Lloyd D et al. (2020)
    The ELIXIR Human Copy Number Variations Community: building bioinformatics infrastructure for research
    F1000Res, 9
    DOI 10.12688/f1000research.24887.1, PubMed 34367618
45. Seppälä TT, Dominguez-Valentin M, Sampson JR, Møller P (2020)
    Prospective observational data informs understanding and future management of Lynch syndrome: insights from the Prospective Lynch Syndrome Database (PLSD)
    Fam Cancer, 20 (1), 35-39
    DOI 10.1007/s10689-020-00193-2, PubMed 32507935
46. Serguienko A, Braadland P, Meza-Zepeda LA, Bjerkehagen B, Myklebost O (2020)
    Accurate 3-gene-signature for early diagnosis of liposarcoma progression
    Clin Sarcoma Res, 10, 4
    DOI 10.1186/s13569-020-0126-1, PubMed 32158531
47. Steinhaeuser SS, Morera E, Budkova Z, Schepsky A, Wang Q, Rolfsson O, Riedel A, Krueger A, Hilmarsdottir B, Maelandsmo GM, Valdimarsdottir B, Sigurdardottir AK, Agnarsson BA, Jonasson JG, Ingthorsson S, Traustadottir GA, Oskarsson T, Gudjonsson T (2020)
    ECM1 secreted by HER2-overexpressing breast cancer cells promotes formation of a vascular niche accelerating cancer cell migration and invasion
    Lab Invest, 100 (7), 928-944
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