Publications 2025

ElAbd H, Pesesky M, Innocenti G, Chung BK, Mahdy AKH, Kriukova V, Kulsvehagen L, Strobbe D, Stühler C, Mayr G, May DH, Prinzensteiner M, Steiert TA, Tran F, Hadjihannas MV, Günther R, Rosati E, Mucha S, Lieb W, Ziemann M, Dempfle A, Braun F, Folseraas T, Hov JR, Melum E et al. (2025)
T and B cell responses against Epstein-Barr virus in primary sclerosing cholangitis
Nat Med (in press)
DOI 10.1038/s41591-025-03692-w, PubMed 40500415

Fossdal G, Braadland P, Hov JR, Husebye ES, Folseraas T, Ueland PM, Ulvik A, Karlsen TH, Berge RK, Vesterhus M (2025)
Mitochondrial dysfunction and lipid alterations in primary sclerosing cholangitis
Scand J Gastroenterol, 60 (2), 165-173
DOI 10.1080/00365521.2024.2447521, PubMed 39764583

Holmer M, Ingre M, Färkkilä M, Ponsioen C, Mol B, Schramm C, Folseraas T, Wiencke K, Cazzagon N, Catanzaro E, Molinaro A, Nilsson E, Vessby J, Kechagias S, Nyhlin N, Werner M, Bergquist A (2025)
Cirrhosis and age are key determinants of HCC risk in individuals with primary sclerosing cholangitis: A multicenter longitudinal cohort study
Hepatology (in press)
DOI 10.1097/HEP.0000000000001351, PubMed 40238209

Singh Y, Eaton JE, Venkatesh SK, Welle CL, Smith B, Faghani S, Vesterhus M, Karlsen TH, Jorgensen KK, Folseraas T, Petrovic K, Negard A, Bjoerk I, Abildgaard A, Gulamhusein AF, Jhaveri K, Gores GJ, Ilyas SI, Taner T, Heimbach JK, Diwan TS, LaRusso NF, Lazaridis KN, Erickson BJ (2025)
Deep learning analysis of magnetic resonance imaging accurately detects early-stage perihilar cholangiocarcinoma in patients with primary sclerosing cholangitis
Hepatology (in press)
DOI 10.1097/HEP.0000000000001314, PubMed 40112296

Yaqub S, Busund S, Smedman TM, Syversveen T, Khan A, Solheim JM, Folseraas T, Wiencke K, Lassen K, Dueland S, Line PD (2025)
Liver transplantation for locally advanced non-resectable intrahepatic cholangiocarcinoma treated with neoadjuvant therapy: early results from the TESLA trial
Br J Surg, 112 (3)
DOI 10.1093/bjs/znaf054, PubMed 40099404

Publications 2024

Grimsrud MM, Forster M, Goeppert B, Hemmrich-Stanisak G, Sax I, Grzyb K, Braadland PR, Charbel A, Metzger C, Albrecht T, Steiert TA, Schlesner M, Manns MP, Vogel A, Yaqub S, Karlsen TH, Schirmacher P, Boberg KM, Franke A, Roessler S, Folseraas T (2024)
Whole-exome sequencing reveals novel cancer genes and actionable targets in biliary tract cancers in primary sclerosing cholangitis
Hepatol Commun, 8 (7)
DOI 10.1097/HC9.0000000000000461, PubMed 38967597

Poch T, Bahn J, Casar C, Krause J, Evangelakos I, Gilladi H, Kunzmann LK, Laschtowitz A, Iuso N, Schäfer AM, Liebig LA, Steinmann S, Sebode M, Folseraas T, Engesæter LK, Karlsen TH, Franke A, Hubner N, Schlein C, Galun E, Huber S, Lohse AW, Gagliani N, Schwinge D, Schramm C (2024)
Intergenic risk variant rs56258221 skews the fate of naive CD4⁺ T cells via miR4464-BACH2 interplay in primary sclerosing cholangitis
Cell Rep Med, 5 (7), 101620
DOI 10.1016/j.xcrm.2024.101620, PubMed 38901430

van Keulen AM, Buettner S, Olthof PB, Klümpen HJ, Erdmann JI, Izquierdo-Sanchez L, Banales JM, Goeppert B, Roessler S, Zieniewicz K, Lamarca A, Valle JW, La Casta A, Hoogwater FJH, Donadon M, Scheiter A, Marzioni M, Adeva J, Kiudeliene E, Fernández JMU, Vidili G, Mocan T, Fabris L, Krawczyk M, Folseraas T et al. (2024)
Comparing Survival of Perihilar Cholangiocarcinoma After R1 Resection Versus Palliative Chemotherapy for Unresected Localized Disease
Ann Surg Oncol, 31 (10), 6495-6503
DOI 10.1245/s10434-024-15582-5, PubMed 38896226

Publications 2023

Braadland PR, Bergquist A, Kummen M, Bossen L, Engesæter LK, Reims HM, Björk I, Grzyb K, Abildgaard A, Småstuen MC, Folseraas T, Trøseid M, Ulvik A, Ueland PM, Melum E, Line PD, Høivik ML, Grønbæk H, Karlsen TH, Vesterhus M, Hov JR (2023)
Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation
J Hepatol, 79 (4), 955-966
DOI 10.1016/j.jhep.2023.05.038, PubMed 37328069

De Muynck K, Heyerick L, De Ponti FF, Vanderborght B, Meese T, Van Campenhout S, Baudonck L, Gijbels E, Rodrigues PM, Banales JM, Vesterhuus M, Folseraas T, Scott CL, Vinken M, Van der Linden M, Hoorens A, Van Dorpe J, Lefere S, Geerts A, Van Nieuwerburgh F, Verhelst X, Van Vlierberghe H, Devisscher L (2023)
Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis
Hepatology, 79 (2), 269-288
DOI 10.1097/HEP.0000000000000557, PubMed 37535809

Grant CW, Juran BD, Ali AH, Schlicht EM, Bianchi JK, Hu X, Liang Y, Jarrell Z, Liu KH, Go YM, Jones DP, Walker DI, Miller GW, Folseraas T, Karlsen TH, LaRusso NF, Gores GJ, Athreya AP, Lazaridis KN (2023)
Environmental chemicals and endogenous metabolites in bile of USA and Norway patients with primary sclerosing cholangitis
Exposome, 3 (1), osac011
DOI 10.1093/exposome/osac011, PubMed 36687160

Han Y, Byun J, Zhu C, Sun R, Roh JY, Cordell HJ, Lee HS, Shaw VR, Kang SW, Razjouyan J, Cooley MA, Hassan MM, Siminovitch KA, Folseraas T, Ellinghaus D, Bergquist A, Rushbrook SM, Franke A, Karlsen TH, Lazaridis KN, International PSC Study Group, McGlynn KA, Roberts LR, Amos CI (2023)
Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis
Nat Commun, 14 (1), 1069
DOI 10.1038/s41467-023-36678-8, PubMed 36828809

Helgadottir H, Folseraas T, Kemmerich G, Aabakken L, Jørgensen KK, Vesterhus M (2023)
[Primary sclerosing cholangitis]
Tidsskr Nor Laegeforen, 143 (17)
DOI 10.4045/tidsskr.23.0156, PubMed 37987062

Lapitz A, Azkargorta M, Milkiewicz P, Olaizola P, Zhuravleva E, Grimsrud MM, Schramm C, Arbelaiz A, O'Rourke CJ, La Casta A, Milkiewicz M, Pastor T, Vesterhus M, Jimenez-Agüero R, Dill MT, Lamarca A, Valle JW, Macias RIR, Izquierdo-Sanchez L, Pérez Castaño Y, Caballero-Camino FJ, Riaño I, Krawczyk M, Ibarra C, Bustamante J et al. (2023)
Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma
J Hepatol, 79 (1), 93-108
DOI 10.1016/j.jhep.2023.02.027, PubMed 36868481

Mikalsen IM, Breder S, Medhus AW, Folseraas T, Aabakken L, Ånonsen KV (2023)
ERCP for the initial management of malignant biliary obstruction - real world data on 596 procedures
Scand J Gastroenterol, 59 (3), 369-377
DOI 10.1080/00365521.2023.2282375, PubMed 37994406

Steiert TA, Parra G, Gut M, Arnold N, Trotta JR, Tonda R, Moussy A, Gerber Z, Abuja PM, Zatloukal K, Röcken C, Folseraas T, Grimsrud MM, Vogel A, Goeppert B, Roessler S, Hinz S, Schafmayer C, Rosenstiel P, Deleuze JF, Gut IG, Franke A, Forster M (2023)
A critical spotlight on the paradigms of FFPE-DNA sequencing
Nucleic Acids Res, 51 (14), 7143-7162
DOI 10.1093/nar/gkad519, PubMed 37351572

Wacker EM, Uellendahl-Werth F, Bej S, Wolkenhauer O, Vesterhus M, Lieb W, Franke A, Karlsen TH, Folseraas T, Ellinghaus D (2023)
Whole blood RNA sequencing identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis
JHEP Rep, 6 (2), 100988
DOI 10.1016/j.jhepr.2023.100988, PubMed 38304234

Yaqub S, Bjørk I, Sugulle M, Folseraas T (2023)
Biopsy helpful in diagnosing a liver mass in pregnancy: focal nodular hyperplasia
Lancet, 402 (10403), e10
DOI 10.1016/S0140-6736(23)01606-9, PubMed 37633669

Publications 2022

Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Blandino Ortiz A, de Salazar A, Garrido Chercoles A, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A et al. (2022)
Detailed stratified GWAS analysis for severe COVID-19 in four European populations
Hum Mol Genet, 31 (23), 3945-3966
DOI 10.1093/hmg/ddac158, PubMed 35848942

Eliasson J, Lo B, Schramm C, Chazouilleres O, Folseraas T, Beuers U, Ytting H (2022)
Survey uncovering variations in the management of primary sclerosing cholangitis across Europe
JHEP Rep, 4 (11), 100553
DOI 10.1016/j.jhepr.2022.100553, PubMed 36164416

Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł et al. (2022)
Cholangiocarcinoma landscape in Europe: Diagnostic, prognostic and therapeutic insights from the ENSCCA Registry
J Hepatol, 76 (5), 1109-1121
DOI 10.1016/j.jhep.2021.12.010, PubMed 35167909

Lei L, Bruneau A, El Mourabit H, Guégan J, Folseraas T, Lemoinne S, Karlsen TH, Hoareau B, Morichon R, Gonzalez-Sanchez E, Goumard C, Ratziu V, Charbord P, Gautheron J, Tacke F, Jaffredo T, Cadoret A, Housset C (2022)
Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis
Hepatology, 76 (5), 1360-1375
DOI 10.1002/hep.32456, PubMed 35278227

Nooijen LE, Banales JM, de Boer MT, Braconi C, Folseraas T, Forner A, Holowko W, Hoogwater FJH, Klümpen HJ, Groot Koerkamp B, Lamarca A, La Casta A, López-López F, Izquierdo-Sánchez L, Scheiter A, Utpatel K, Swijnenburg RJ, Kazemier G, Erdmann JI,   ENSCCA Group (2022)
Impact of Positive Lymph Nodes and Resection Margin Status on the Overall Survival of Patients with Resected Perihilar Cholangiocarcinoma: The ENSCCA Registry
Cancers (Basel), 14 (10)
DOI 10.3390/cancers14102389, PubMed 35625993

Singh Y, Jons WA, Eaton JE, Vesterhus M, Karlsen T, Bjoerk I, Abildgaard A, Jorgensen KK, Folseraas T, Little D, Gulamhusein AF, Petrovic K, Negard A, Conte GM, Sobek JD, Jagtap J, Venkatesh SK, Gores GJ, LaRusso NF, Lazaridis KN, Erickson BJ (2022)
Algebraic topology-based machine learning using MRI predicts outcomes in primary sclerosing cholangitis
Eur Radiol Exp, 6 (1), 58
DOI 10.1186/s41747-022-00312-x, PubMed 36396865

Uellendahl-Werth F, Maj C, Borisov O, Juzenas S, Wacker EM, Jørgensen IF, Steiert TA, Bej S, Krawitz P, Hoffmann P, Schramm C, Wolkenhauer O, Banasik K, Brunak S, Schreiber S, Karlsen TH, Degenhardt F, Nöthen M, Franke A, Folseraas T, Ellinghaus D (2022)
Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease
Commun Biol, 5 (1), 80
DOI 10.1038/s42003-022-03031-6, PubMed 35058554

Yu J, Refsum E, Helsingen LM, Folseraas T, Ploner A, Wieszczy P, Barua I, Jodal HC, Melum E, Løberg M, Blom J, Bretthauer M, Adami HO, Kalager M, Ye W (2022)
Risk of hepato-pancreato-biliary cancer is increased by primary sclerosing cholangitis in patients with inflammatory bowel disease: A population-based cohort study
United European Gastroenterol J, 10 (2), 212-224
DOI 10.1002/ueg2.12204, PubMed 35107865

Publications 2021

Aune D, Sen A, Norat T, Riboli E, Folseraas T (2021)
Primary sclerosing cholangitis and the risk of cancer, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of cohort studies
Sci Rep, 11 (1), 10646
DOI 10.1038/s41598-021-90175-w, PubMed 34017024

Dhillon AK, Rupp C, Bergquist A, Voitl R, Folseraas T, Trøseid M, Midttun Ø, Ueland PM, Karlsen TH, Vesterhus M, Kummen M, Hov JR (2021)
Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
Scand J Gastroenterol, 56 (4), 443-452
DOI 10.1080/00365521.2021.1880627, PubMed 33583308

Fossdal G, Mjelle AB, Wiencke K, Bjørk I, Gilja OH, Folseraas T, Karlsen TH, Rosenberg W, Giil LM, Vesterhus M (2021)
Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF
JHEP Rep, 3 (5), 100328
DOI 10.1016/j.jhepr.2021.100328, PubMed 34485881

Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RI, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW (2021)
REPLY
Hepatology, 74 (4), 2319-2321
DOI 10.1002/hep.31904, PubMed 33998692

Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW (2021)
REPLY
Hepatology, 74 (2), 1129-1131
DOI 10.1002/hep.31740, PubMed 33550618

Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW (2021)
Letter to the Editor: Does Multiple Intrahepatic Cholangiocarcinoma Worsen Prognosis as "M1" Stage? REPLY
Hepatology, 74 (2), 1129-1131
DOI 10.1002/hep.31740

Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW, Group: on behalf of the European Network for the Study of Cholangiocarcinoma (ENS-CCA) (2021)
Liver Metastases of Intrahepatic Cholangiocarcinoma: Implications for an Updated Staging System
Hepatology, 73 (6), 2311-2325
DOI 10.1002/hep.31598, PubMed 33073396

Mousa OY, Juran BD, McCauley BM, Vesterhus MN, Folseraas T, Turgeon CT, Ali AH, Schlicht EM, Atkinson EJ, Hu C, Harnois D, Carey EJ, Gossard AA, Oglesbee D, Eaton JE, LaRusso NF, Gores GJ, Karlsen TH, Lazaridis KN (2021)
Bile Acid Profiles in Primary Sclerosing Cholangitis and Their Ability to Predict Hepatic Decompensation
Hepatology, 74 (1), 281-295
DOI 10.1002/hep.31652, PubMed 33226645

Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology, 75 (1), 59-73
DOI 10.1002/hep.32125, PubMed 34435693

Vesterhus M, Wiencke K, Haukeland JW, Frigstad SO, Karlsen LN, Jørgensen KK, Folseraas T (2021)
[Diagnosis and treatment of autoimmune hepatitis]
Tidsskr Nor Laegeforen, 141 (10)
DOI 10.4045/tidsskr.20.1045, PubMed 34182737

Publications 2020

Goeppert B, Folseraas T, Roessler S, Kloor M, Volckmar AL, Endris V, Buchhalter I, Stenzinger A, Grzyb K, Grimsrud MM, Gornicka B, von Seth E, Reynolds GM, Franke A, Gotthardt DN, Mehrabi A, Cheung A, Verheij J, Arola J, Mäkisalo H, Eide TJ, Weidemann S, Cheville JC, Mazza G, Hirschfield GM et al. (2020)
Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities
Hepatology, 72 (4), 1253-1266
DOI 10.1002/hep.31110, PubMed 31925805

Severe Covid-19 GWAS Group, Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J, Prati D, Baselli G, Asselta R, Grimsrud MM, Milani C, Aziz F, Kässens J, May S, Wendorff M, Wienbrandt L, Uellendahl-Werth F, Zheng T, Yi X, de Pablo R, Chercoles AG, Palom A, Garcia-Fernandez AE et al. (2020)
Genomewide Association Study of Severe Covid-19 with Respiratory Failure
N Engl J Med, 383 (16), 1522-1534
DOI 10.1056/NEJMoa2020283, PubMed 32558485

Vedeld HM, Folseraas T, Lind GE (2020)
Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis - The promise of DNA methylation and molecular biomarkers
JHEP Rep, 2 (5), 100143
DOI 10.1016/j.jhepr.2020.100143, PubMed 32939446

Publications 2019

Carpino G, Cardinale V, Folseraas T, Overi D, Grzyb K, Costantini D, Berloco PB, Di Matteo S, Karlsen TH, Alvaro D, Gaudio E (2019)
Neoplastic Transformation of the Peribiliary Stem Cell Niche in Cholangiocarcinoma Arisen in Primary Sclerosing Cholangitis
Hepatology, 69 (2), 622-638
DOI 10.1002/hep.30210, PubMed 30102768

Grimsrud MM, Folseraas T (2019)
Pathogenesis, diagnosis and treatment of premalignant and malignant stages of cholangiocarcinoma in primary sclerosing cholangitis
Liver Int, 39 (12), 2230-2237
DOI 10.1111/liv.14180, PubMed 31216595

Publications 2018

Thorgersen EB, Melum E, Folseraas T, Larsen SG, Line PD (2018)
Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report
World J Surg Oncol, 16 (1), 180
DOI 10.1186/s12957-018-1482-7, PubMed 30185175

Publications 2017

Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J et al. (2017)
Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
Gut, 67 (8), 1517-1524
DOI 10.1136/gutjnl-2016-313598, PubMed 28779025

Carpino G, Cardinale V, Folseraas T, Overi D, Floreani A, Franchitto A, Onori P, Cazzagon N, Berloco PB, Karlsen TH, Alvaro D, Gaudio E (2017)
Hepatic Stem/Progenitor Cell Activation Differs between Primary Sclerosing and Primary Biliary Cholangitis
Am J Pathol, 188 (3), 627-639
DOI 10.1016/j.ajpath.2017.11.010, PubMed 29248458

Chung BK, Karlsen TH, Folseraas T (2017)
Cholangiocytes in the pathogenesis of primary sclerosing cholangitis and development of cholangiocarcinoma
Biochim Biophys Acta Mol Basis Dis, 1864 (4 Pt B), 1390-1400
DOI 10.1016/j.bbadis.2017.08.020, PubMed 28844951

Henriksen EKK, Viken MK, Wittig M, Holm K, Folseraas T, Mucha S, Melum E, Hov JR, Lazaridis KN, Juran BD, Chazouillères O, Färkkilä M, Gotthardt DN, Invernizzi P, Carbone M, Hirschfield GM, Rushbrook SM, Goode E, UK-PSC Consortium, Ponsioen CY, Weersma RK, Eksteen B, Yimam KK, Gordon SC, Goldberg D et al. (2017)
HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry
HLA, 90 (4), 228-233
DOI 10.1111/tan.13076, PubMed 28695657

Karlsen TH, Folseraas T, Thorburn D, Vesterhus M (2017)
Primary sclerosing cholangitis - a comprehensive review
J Hepatol, 67 (6), 1298-1323
DOI 10.1016/j.jhep.2017.07.022, PubMed 28802875

Publications 2016

Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen JB, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RI, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJ, Alvaro D (2016)
Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Nat Rev Gastroenterol Hepatol, 13 (5), 261-80
DOI 10.1038/nrgastro.2016.51, PubMed 27095655

Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, Hübenthal M, Folseraas T, Wang Y, Esko T, Metspalu A, Westra HJ, Franke L, Pers TH, Weersma RK, Collij V, D'Amato M, Halfvarson J, Jensen AB, Lieb W, Degenhardt F, Forstner AJ et al. (2016)
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Nat Genet, 48 (5), 510-8
DOI 10.1038/ng.3528, PubMed 26974007

Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Gotthardt DN, Ellinghaus D, Braun F et al. (2016)
Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
Nat Genet, 49 (2), 269-273
DOI 10.1038/ng.3745, PubMed 27992413

Publications 2015

Folseraas T, Boberg KM (2015)
Cancer Risk and Surveillance in Primary Sclerosing Cholangitis
Clin Liver Dis, 20 (1), 79-98
DOI 10.1016/j.cld.2015.08.014, PubMed 26593292

Folseraas T, Liaskou E, Anderson CA, Karlsen TH (2015)
Genetics in PSC: what do the "risk genes" teach us?
Clin Rev Allergy Immunol, 48 (2-3), 154-64
DOI 10.1007/s12016-014-8417-z, PubMed 24736995

Li J, Jørgensen SF, Maggadottir SM, Bakay M, Warnatz K, Glessner J, Pandey R, Salzer U, Schmidt RE, Perez E, Resnick E, Goldacker S, Buchta M, Witte T, Padyukov L, Videm V, Folseraas T, Atschekzei F, Elder JT, Nair RP, Winkelmann J, Gieger C, Nöthen MM, Büning C, Brand S et al. (2015)
Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells
Nat Commun, 6, 6804
DOI 10.1038/ncomms7804, PubMed 25891430

Wannhoff A, Folseraas T, Brune M, Rupp C, Friedrich K, Knierim J, Weiss KH, Sauer P, Flechtenmacher C, Schirmacher P, Stremmel W, Hov JR, Gotthardt DN (2015)
A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis
United European Gastroenterol J, 4 (1), 84-91
DOI 10.1177/2050640615581577, PubMed 26966527

Publications 2014

Rupp C, Friedrich K, Folseraas T, Wannhoff A, Bode KA, Weiss KH, Schirmacher P, Sauer P, Stremmel W, Gotthardt DN (2014)
Fut2 genotype is a risk factor for dominant stenosis and biliary candida infections in primary sclerosing cholangitis
Aliment Pharmacol Ther, 39 (8), 873-82
DOI 10.1111/apt.12663, PubMed 24612312

Publications 2013

Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK et al. (2013)
Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
Hepatology, 58 (3), 1074-83
DOI 10.1002/hep.25977, PubMed 22821403

Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismüller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Müller T, Srivastava B, Dalekos G, Nöthen MM, Herms S et al. (2013)
Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
Nat Genet, 45 (6), 670-5
DOI 10.1038/ng.2616, PubMed 23603763

Wannhoff A, Hov JR, Folseraas T, Rupp C, Friedrich K, Anmarkrud JA, Weiss KH, Sauer P, Schirmacher P, Boberg KM, Stremmel W, Karlsen TH, Gotthardt DN (2013)
FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis
J Hepatol, 59 (6), 1278-84
DOI 10.1016/j.jhep.2013.08.005, PubMed 23958938

Publications 2012

Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismüller TJ, Gotthardt DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Björnsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE et al. (2012)
Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
J Hepatol, 57 (2), 366-75
DOI 10.1016/j.jhep.2012.03.031, PubMed 22521342

Publications 2011

Folseraas T, Karlsen TH (2011)
To MMP or not to MMP: a role for matrix metalloproteinase 3 in primary sclerosing cholangitis?
Liver Int, 31 (6), 751-4
DOI 10.1111/j.1478-3231.2011.02471.x, PubMed 21645205

Folseraas T, Melum E, Franke A, Karlsen TH (2011)
Genetics in primary sclerosing cholangitis
Best Pract Res Clin Gastroenterol, 25 (6), 713-26
DOI 10.1016/j.bpg.2011.09.010, PubMed 22117637

Janse M, Lamberts LE, Franke L, Raychaudhuri S, Ellinghaus E, Muri Boberg K, Melum E, Folseraas T, Schrumpf E, Bergquist A, Björnsson E, Fu J, Jan Westra H, Groen HJ, Fehrmann RS, Smolonska J, van den Berg LH, Ophoff RA, Porte RJ, Weismüller TJ, Wedemeyer J, Schramm C, Sterneck M, Günther R, Braun F et al. (2011)
Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9
Hepatology, 53 (6), 1977-85
DOI 10.1002/hep.24307, PubMed 21425313