Publications published since 2008 from OUS - Norwegian PSC Research Center

389 publications found

Publications 2024

  1. Gregersen I, Kong XY, Kooijman S, Foyn H, Grannes H, Olsen MB, Lone AM, Yang K, Quiles-Jiménez A, Tran M, Øgaard J, Segers FM, Rashidi A, Sagen EL, Lauritzen KH, Pronk ACM, de Boer JF, Holven KB, Melum E, Aukrust P, Taskén K, Holm S, Rensen PCN, Dahl TB, Halvorsen B (2024)
    T cells with increased responsiveness cause obesity in mice without diet intervention
    iScience, 27 (4), 109471
    DOI 10.1016/j.isci.2024.109471, PubMed 38551005
  2. He MM, Wang K, Lo CH, Zhang Y, Polychronidis G, Knudsen MD, Zhong R, Ma Y, Wu K, Chan AT, Giovannucci EL, Ogino S, Ng K, Meyerhardt JA, Song M (2024)
    Post-diagnostic multivitamin supplement use and colorectal cancer survival: A prospective cohort study
    Cancer (in press)
    DOI 10.1002/cncr.35234, PubMed 38319287
  3. Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS (2024)
    Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
    Nature, 626 (8001), E19
    DOI 10.1038/s41586-024-07164-y, PubMed 38336833
  4. Jaeger JW, Brandt A, Gui W, Yergaliyev T, Hernández-Arriaga A, Muthu MM, Edlund K, Elashy A, Molinaro A, Möckel D, Sarges J, Halibasic E, Trauner M, Kahles F, Rolle-Kampczyk U, Hengstler J, Schneider CV, Lammers T, Marschall HU, von Bergen M, Camarinha-Silva A, Bergheim I, Trautwein C, Schneider KM (2024)
    Microbiota modulation by dietary oat beta-glucan prevents steatotic liver disease progression
    JHEP Rep, 6 (3), 100987
    DOI 10.1016/j.jhepr.2023.100987, PubMed 38328439
  5. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2024)
    Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
    Sci Rep, 14 (1), 3704
    DOI 10.1038/s41598-024-54117-6, PubMed 38355714
  6. Karlsen TH, Rutter H, Carrieri P, Zelber-Sagi S, Engebretsen E, Hutchinson S, Voigt K, Guha N, Berzigotti A, Schomerus G, Gines P, Buti M, Burra P, Manns MP, Krag A, Kleinert S (2024)
    The EASL-Lancet Commission on liver health in Europe: prevention, case-finding, and early diagnosis to reduce liver-related mortality
    Lancet, 403 (10436), 1522-1524
    DOI 10.1016/S0140-6736(24)00204-6, PubMed 38359860
  7. Lin W, Gerullat L, Braadland PR, Fournier A, Hov JR, Globisch D (2024)
    Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4-Nitrophenyl-2H-azirine
    Angew Chem Int Ed Engl, 63 (14), e202318579
    DOI 10.1002/anie.202318579, PubMed 38235602
  8. Nikitina D, Lukosevicius R, Tilinde D, Muskieta T, Hov JR, Melum E, Klovins J, Org E, Kiudelis G, Kupcinskas J, Skieceviciene J (2024)
    Cell-Free Microbial DNA Analysis: Effects of Blood Plasma and Serum Quantity, Biobanking Protocols, and Isolation Kits
    Biopreserv Biobank (in press)
    DOI 10.1089/bio.2023.0048, PubMed 38416864
  9. Oldereid TS, Jiang X, Øgaard J, Schrumpf E, Bjørnholt JV, Rasmussen H, Melum E (2024)
    Microbial exposure during early life regulates development of bile duct inflammation
    Scand J Gastroenterol, 59 (2), 192-201
    DOI 10.1080/00365521.2023.2278423, PubMed 37997753
  10. Raju SC, Molinaro A, Awoyemi A, Jørgensen SF, Braadland PR, Nendl A, Seljeflot I, Ueland PM, McCann A, Aukrust P, Vestad B, Mayerhofer C, Broch K, Gullestad L, Lappegård KT, Halvorsen B, Kristiansen K, Hov JR, Trøseid M (2024)
    Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity
    Genome Med, 16 (1), 27
    DOI 10.1186/s13073-024-01296-6, PubMed 38331891
  11. Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M (2024)
    Author Correction: Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
    Nat Med, 30 (1), 303
    DOI 10.1038/s41591-023-02529-8, PubMed 37587221
  12. Trøseid M, Molinaro A, Gelpi M, Vestad B, Kofoed KF, Fuchs A, Køber L, Holm K, Benfield T, Ueland PM, Hov JR, Nielsen SD, Knudsen AD (2024)
    Gut Microbiota Alterations and Circulating Imidazole Propionate Levels Are Associated With Obstructive Coronary Artery Disease in People With HIV
    J Infect Dis, 229 (3), 898-907
    DOI 10.1093/infdis/jiad604, PubMed 38195204
  13. Yang M, Kaarbø M, Myhre V, Reims HM, Karlsen TH, Wang J, Rognes T, Halvorsen B, Fevang B, Lundin KEA, Aukrust P, Bjørås M, Jørgensen SF (2024)
    Altered Genome-Wide DNA Methylation in the Duodenum of Common Variable Immunodeficiency Patients
    J Clin Immunol, 44 (6), 133
    DOI 10.1007/s10875-024-01726-5, PubMed 38780872

Publications 2023

  1. Al Khatib I, Deng J, Lei Y, Torres-Odio S, Rojas GR, Newman LE, Chung BK, Symes A, Zhang H, Huang SN, Pommier Y, Khan A, Shadel GS, West AP, Gibson WT, Shutt TE (2023)
    Activation of the cGAS-STING innate immune response in cells with deficient mitochondrial topoisomerase TOP1MT
    Hum Mol Genet, 32 (15), 2422-2440
    DOI 10.1093/hmg/ddad062, PubMed 37129502
  2. Andersen IM, Reims HM, Grzyb K, Fevang B, Melum E, Aukrust P, Wiencke K, Nordøy I, Line PD, Jørgensen SF (2023)
    Long-term survival after liver transplantation in patients with common variable immunodeficiency
    Liver Transpl, 29 (8), 894-899
    DOI 10.1097/LVT.0000000000000130, PubMed 36932715
  3. Bergsmark T, Engesæter LK, Rasmussen A, Bennet W, Nordin A, Pall V, Line PD, Ericzon BG, Melum E (2023)
    Long-term survival after liver transplantation for alcohol-related liver disease in the Nordic countries
    Scand J Gastroenterol, 58 (8), 923-930
    DOI 10.1080/00365521.2023.2184193, PubMed 36872559
  4. Braadland PR, Bergquist A, Kummen M, Bossen L, Engesæter LK, Reims HM, Björk I, Grzyb K, Abildgaard A, Småstuen MC, Folseraas T, Trøseid M, Ulvik A, Ueland PM, Melum E, Line PD, Høivik ML, Grønbæk H, Karlsen TH, Vesterhus M, Hov JR (2023)
    Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation
    J Hepatol, 79 (4), 955-966
    DOI 10.1016/j.jhep.2023.05.038, PubMed 37328069
  5. Busek M, Aizenshtadt A, Koch T, Frank A, Delon L, Martinez MA, Golovin A, Dumas C, Stokowiec J, Gruenzner S, Melum E, Krauss S (2023)
    Pump-less, recirculating organ-on-a-chip (rOoC) platform
    Lab Chip, 23 (4), 591-608
    DOI 10.1039/d2lc00919f, PubMed 36655405
  6. Carbone M, Della Penna A, Mazzarelli C, De Martin E, Villard C, Bergquist A, Line PD, Neuberger JM, Al-Shakhshir S, Trivedi PJ, Baumann U, Cristoferi L, Hov J, Fischler B, Hadzic NH, Debray D, D'Antiga L, Selzner N, Belli LS, Nadalin S (2023)
    Liver Transplantation for Primary Sclerosing Cholangitis (PSC) With or Without Inflammatory Bowel Disease (IBD)-A European Society of Organ Transplantation (ESOT) Consensus Statement
    Transpl Int, 36, 11729
    DOI 10.3389/ti.2023.11729, PubMed 37841645
  7. De Muynck K, Heyerick L, De Ponti FF, Vanderborght B, Meese T, Van Campenhout S, Baudonck L, Gijbels E, Rodrigues PM, Banales JM, Vesterhuus M, Folseraas T, Scott CL, Vinken M, Van der Linden M, Hoorens A, Van Dorpe J, Lefere S, Geerts A, Van Nieuwerburgh F, Verhelst X, Van Vlierberghe H, Devisscher L (2023)
    Osteopontin characterizes bile duct-associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis
    Hepatology, 79 (2), 269-288
    DOI 10.1097/HEP.0000000000000557, PubMed 37535809
  8. Ecklu-Mensah G, Choo-Kang C, Maseng MG, Donato S, Bovet P, Viswanathan B, Bedu-Addo K, Plange-Rhule J, Oti Boateng P, Forrester TE, Williams M, Lambert EV, Rae D, Sinyanya N, Luke A, Layden BT, O'Keefe S, Gilbert JA, Dugas LR (2023)
    Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: the METS-microbiome study
    Nat Commun, 14 (1), 5160
    DOI 10.1038/s41467-023-40874-x, PubMed 37620311
  9. Gjersvik P, Falk RS, Roscher I, Rizvi SMH, Mjøen G, Gude E, Leuckfeld I, Boberg KM, Veierød MB, Robsahm TE (2023)
    Rates of Second Tumor, Metastasis, and Death From Cutaneous Squamous Cell Carcinoma in Patients With and Without Transplant-Associated Immunosuppression
    JAMA Dermatol, 159 (9), 923-929
    DOI 10.1001/jamadermatol.2023.2029, PubMed 37466985
  10. Grant CW, Juran BD, Ali AH, Schlicht EM, Bianchi JK, Hu X, Liang Y, Jarrell Z, Liu KH, Go YM, Jones DP, Walker DI, Miller GW, Folseraas T, Karlsen TH, LaRusso NF, Gores GJ, Athreya AP, Lazaridis KN (2023)
    Environmental chemicals and endogenous metabolites in bile of USA and Norway patients with primary sclerosing cholangitis
    Exposome, 3 (1), osac011
    DOI 10.1093/exposome/osac011, PubMed 36687160
  11. Graupera I, Thiele M, Ma AT, Serra-Burriel M, Pich J, Fabrellas N, Caballeria L, de Knegt RJ, Grgurevic I, Reichert M, Roulot D, Schattenberg JM, Pericas JM, Angeli P, Tsochatzis EA, Guha IN, Garcia-Retortillo M, Morillas RM, Hernández R, Hoyo J, Fuentes M, Madir A, Juanola A, Soria A, Juan M et al. (2023)
    Correction: LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries
    BMC Public Health, 23 (1), 923
    DOI 10.1186/s12889-023-15867-6, PubMed 37217864
  12. Gui W, Hole MJ, Molinaro A, Edlund K, Jørgensen KK, Su H, Begher-Tibbe B, Gaßler N, Schneider CV, Muthukumarasamy U, Mohs A, Liao L, Jaeger J, Mertens CJ, Bergheim I, Strowig T, Hengstler JG, Hov JR, Marschall HU, Trautwein C, Schneider KM (2023)
    Colitis ameliorates cholestatic liver disease via suppression of bile acid synthesis
    Nat Commun, 14 (1), 3304
    DOI 10.1038/s41467-023-38840-8, PubMed 37280200
  13. Han Y, Byun J, Zhu C, Sun R, Roh JY, Cordell HJ, Lee HS, Shaw VR, Kang SW, Razjouyan J, Cooley MA, Hassan MM, Siminovitch KA, Folseraas T, Ellinghaus D, Bergquist A, Rushbrook SM, Franke A, Karlsen TH, Lazaridis KN, International PSC Study Group, McGlynn KA, Roberts LR, Amos CI (2023)
    Multitrait genome-wide analyses identify new susceptibility loci and candidate drugs to primary sclerosing cholangitis
    Nat Commun, 14 (1), 1069
    DOI 10.1038/s41467-023-36678-8, PubMed 36828809
  14. Harrison SP, Siller R, Tanaka Y, Chollet ME, de la Morena-Barrio ME, Xiang Y, Patterson B, Andersen E, Bravo-Pérez C, Kempf H, Åsrud KS, Lunov O, Dejneka A, Mowinckel MC, Stavik B, Sandset PM, Melum E, Baumgarten S, Bonanini F, Kurek D, Mathapati S, Almaas R, Sharma K, Wilson SR, Skottvoll FS et al. (2023)
    Scalable production of tissue-like vascularized liver organoids from human PSCs
    Exp Mol Med, 55 (9), 2005-2024
    DOI 10.1038/s12276-023-01074-1, PubMed 37653039
  15. Haukeland JW, Vesterhus MN, Jørgensen KK, Frigstad SO, Karlsen TH (2023)
    [The FIB-4 test as a decision-making tool]
    Tidsskr Nor Laegeforen, 143 (5)
    DOI 10.4045/tidsskr.23.0176, PubMed 36987901
  16. Helgadottir H, Folseraas T, Kemmerich G, Aabakken L, Jørgensen KK, Vesterhus M (2023)
    [Not Available]
    Tidsskr Nor Laegeforen, 143 (17)
    DOI 10.4045/tidsskr.23.0156, PubMed 37987062
  17. Helgadottir H, Vesterhus M (2023)
    Noninvasive evaluation of fibrosis in adult biliary diseases
    Curr Opin Gastroenterol, 39 (2), 83-88
    DOI 10.1097/MOG.0000000000000909, PubMed 36821455
  18. Hole MJ, Jørgensen KK, Holm K, Braadland PR, Meyer-Myklestad MH, Medhus AW, Reikvam DH, Götz A, Grzyb K, Boberg KM, Karlsen TH, Kummen M, Hov JR (2023)
    A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation
    Hepatology, 77 (3), 715-728
    DOI 10.1002/hep.32773, PubMed 36056902
  19. Hole MJ, Jørgensen KK, Holm K, Braadland PR, Meyer-Myklestad MH, Medhus AW, Reikvam DH, Götz A, Grzyb K, Boberg KM, Karlsen TH, Kummen M, Hov JR (2023)
    Reply: The mucosal gut signature in primary sclerosing cholangitis before and after liver transplantation. Is the dysbiosis index really predictive for the recurrence of PSC?
    Hepatology, 77 (6), E188-E189
    DOI 10.1097/HEP.0000000000000340, PubMed 36815351
  20. Hov JR (2023)
    Editorial: dietary interventions to understand and treat primary sclerosing cholangitis-is gluten-free diet a starting point?
    Aliment Pharmacol Ther, 57 (2), 265-266
    DOI 10.1111/apt.17326, PubMed 36565005
  21. Jiang X, Otterdal K, Chung BK, Maucourant C, Rønneberg JD, Zimmer CL, Øgaard J, Boichuk Y, Holm S, Geanon D, Schneditz G, Bergquist A, Björkström NK, Melum E (2023)
    Cholangiocytes Modulate CD100 Expression in the Liver and Facilitate Pathogenic T-Helper 17 Cell Differentiation
    Gastroenterology, 166 (4), 667-679
    DOI 10.1053/j.gastro.2023.11.283, PubMed 37995866
  22. Juul FE, Hov JER, Trøseid M, Johnsen PH, Valeur J (2023)
    [Gut microbiota and intestinal disease –a sober warning]
    Tidsskr Nor Laegeforen, 143 (10)
    DOI 10.4045/tidsskr.23.0121, PubMed 37376933
  23. Krag A, Buti M, Lazarus JV, Allen AM, Bowman J, Burra P, Donnini G, Duseja A, El-Sayed MH, Gastaldelli A, Hainsworth B, Karlsen TH, Kessler M, Korenjak M, Mark HE, Mann JP, Miller V, Pessoa MG, Piñeiro D, Sarin SK, Singh SP, Rinella ME, Willemse J, Younossi ZM, Francque SM (2023)
    Uniting to defeat steatotic liver disease: A global mission to promote healthy livers and healthy lives
    J Hepatol, 79 (5), 1076-1078
    DOI 10.1016/j.jhep.2023.07.029, PubMed 37634993
  24. Lapitz A, Azkargorta M, Milkiewicz P, Olaizola P, Zhuravleva E, Grimsrud MM, Schramm C, Arbelaiz A, O'Rourke CJ, La Casta A, Milkiewicz M, Pastor T, Vesterhus M, Jimenez-Agüero R, Dill MT, Lamarca A, Valle JW, Macias RIR, Izquierdo-Sanchez L, Pérez Castaño Y, Caballero-Camino FJ, Riaño I, Krawczyk M, Ibarra C, Bustamante J et al. (2023)
    Liquid biopsy-based protein biomarkers for risk prediction, early diagnosis, and prognostication of cholangiocarcinoma
    J Hepatol, 79 (1), 93-108
    DOI 10.1016/j.jhep.2023.02.027, PubMed 36868481
  25. Macpherson ME, Skarpengland T, Hov JR, Ranheim T, Vestad B, Dahl TB, Fraz MSA, Michelsen AE, Holven KB, Fevang B, Berge RK, Aukrust P, Halvorsen B, Jørgensen SF (2023)
    Increased Plasma Levels of Triglyceride-Enriched Lipoproteins Associate with Systemic Inflammation, Lipopolysaccharides, and Gut Dysbiosis in Common Variable Immunodeficiency
    J Clin Immunol, 43 (6), 1229-1240
    DOI 10.1007/s10875-023-01475-x, PubMed 36995502
  26. Mayer C, Nehring S, Kücken M, Repnik U, Seifert S, Sljukic A, Delpierre J, Morales-Navarrete H, Hinz S, Brosch M, Chung B, Karlsen T, Huch M, Kalaidzidis Y, Brusch L, Hampe J, Schafmayer C, Zerial M (2023)
    Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease
    EMBO Rep, 24 (9), e57181
    DOI 10.15252/embr.202357181, PubMed 37522754
  27. Mikaeloff F, Gelpi M, Benfeitas R, Knudsen AD, Vestad B, Høgh J, Hov JR, Benfield T, Murray D, Giske CG, Mardinoglu A, Trøseid M, Nielsen SD, Neogi U (2023)
    Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection
    Elife, 12
    DOI 10.7554/eLife.82785, PubMed 36794912
  28. Nendl A, Raju SC, Broch K, Mayerhofer CCK, Holm K, Halvorsen B, Lappegård KT, Moscavitch S, Hov JR, Seljeflot I, Trøseid M, Awoyemi A (2023)
    Intestinal fatty acid binding protein is associated with cardiac function and gut dysbiosis in chronic heart failure
    Front Cardiovasc Med, 10, 1160030
    DOI 10.3389/fcvm.2023.1160030, PubMed 37332580
  29. Oldereid TS, Jiang X, Nordhus KS, Ponzetta A, Bjørnholt JV, Björkström NK, Melum E, Rasmussen H (2023)
    Role of bacteria and microbial metabolites in immune modulation during early life
    Scand J Immunol, 99 (2), e13336
    DOI 10.1111/sji.13336, PubMed 38441196
  30. Schneider KM, Kummen M, Trivedi PJ, Hov JR (2023)
    Role of microbiome in autoimmune liver diseases
    Hepatology (in press)
    DOI 10.1097/HEP.0000000000000506, PubMed 37369002
  31. Serra-Burriel M, Juanola A, Serra-Burriel F, Thiele M, Graupera I, Pose E, Pera G, Grgurevic I, Caballeria L, Piano S, van Kleef L, Reichert M, Roulot D, Pericàs JM, Schattenberg JM, Tsochatztis EA, Guha IN, Garcia-Retortillo M, Hernández R, Hoyo J, Fuentes M, Expósito C, Martínez A, Such P, Madir A et al. (2023)
    Development, validation, and prognostic evaluation of a risk score for long-term liver-related outcomes in the general population: a multicohort study
    Lancet, 402 (10406), 988-996
    DOI 10.1016/S0140-6736(23)01174-1, PubMed 37572680
  32. Serrano-Villar S, Tincati C, Raju SC, Sáenz JS, Moreno E, Bargiela R, Cabello-Ubeda A, Sendagorta E, Kurz A, Perez Molina JA, de Benito A, Hov JR, Fernandez-Lopez L, Muriel A, Del Campo R, Moreno S, Trøseid M, Seifert J, Ferrer M (2023)
    Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer
    Nat Med, 29 (7), 1738-1749
    DOI 10.1038/s41591-023-02407-3, PubMed 37464040
  33. Steiert TA, Parra G, Gut M, Arnold N, Trotta JR, Tonda R, Moussy A, Gerber Z, Abuja PM, Zatloukal K, Röcken C, Folseraas T, Grimsrud MM, Vogel A, Goeppert B, Roessler S, Hinz S, Schafmayer C, Rosenstiel P, Deleuze JF, Gut IG, Franke A, Forster M (2023)
    A critical spotlight on the paradigms of FFPE-DNA sequencing
    Nucleic Acids Res, 51 (14), 7143-7162
    DOI 10.1093/nar/gkad519, PubMed 37351572
  34. Tedbury PR, Manfredi C, Degenhardt F, Conway J, Horwath MC, McCracken C, Sorscher AJ, Moreau S, Wright C, Edwards C, Brewer J, Guarner J, de Wit E, Williamson BN, Suthar MS, Ong YT, Roback JD, Alter DN, Holter JC, Karlsen TH, Sacchi N, Romero-Gómez M, Invernizzi P, Fernández J, Buti M et al. (2023)
    Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity
    FASEB J, 37 (11), e23220
    DOI 10.1096/fj.202300077R, PubMed 37801035
  35. Tran TT, Vaage EB, Mehta A, Chopra A, Tietze L, Kolderup A, Anthi A, König M, Nygaard G, Lind A, Müller F, Nissen-Meyer LS, Magnus P, Trogstad L, Mjaaland S, Søraas A, Midtvedt K, Åsberg A, Barratt-Due A, Medhus AW, Høivik ML, Lundin K, Karlsen RF, Dahle R, Danielsson K et al. (2023)
    Author Correction: Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
    NPJ Vaccines, 8 (1), 4
    DOI 10.1038/s41541-023-00600-6, PubMed 36697432
  36. Trøseid M, Holter JC, Holm K, Vestad B, Sazonova T, Granerud BK, Dyrhol-Riise AM, Holten AR, Tonby K, Kildal AB, Heggelund L, Tveita A, Bøe S, Müller KE, Jenum S, Hov JR, Ueland T, Norwegian SARS-CoV-2 study group (2023)
    Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19
    Crit Care, 27 (1), 69
    DOI 10.1186/s13054-023-04356-2, PubMed 36814280
  37. Wacker EM, Uellendahl-Werth F, Bej S, Wolkenhauer O, Vesterhus M, Lieb W, Franke A, Karlsen TH, Folseraas T, Ellinghaus D (2023)
    Whole blood RNA sequencing identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis
    JHEP Rep, 6 (2), 100988
    DOI 10.1016/j.jhepr.2023.100988, PubMed 38304234
  38. Yaqub S, Bjørk I, Sugulle M, Folseraas T (2023)
    Biopsy helpful in diagnosing a liver mass in pregnancy: focal nodular hyperplasia
    Lancet, 402 (10403), e10
    DOI 10.1016/S0140-6736(23)01606-9, PubMed 37633669

Publications 2022

  1. Awoniyi M, Wang J, Ngo B, Meadows V, Tam J, Viswanathan A, Lai Y, Montgomery S, Farmer M, Kummen M, Thingholm L, Schramm C, Bang C, Franke A, Lu K, Zhou H, Bajaj JS, Hylemon PB, Ting J, Popov YV, Hov JR, Francis HL, Sartor RB (2022)
    Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC
    Gut, 72 (4), 671-685
    DOI 10.1136/gutjnl-2021-326500, PubMed 35705368
  2. Awoyemi A, Hov JR, Trøseid M (2022)
    Phenylacetylglutamine From the Gut Microbiota: A Future Therapeutic Target in Heart Failure?
    Circ Heart Fail, 16 (1), e010222
    DOI 10.1161/CIRCHEARTFAILURE.122.010222, PubMed 36524473
  3. Bergquist A, Weismüller TJ, Levy C, Rupp C, Joshi D, Nayagam JS, Montano-Loza AJ, Lytvyak E, Wunsch E, Milkiewicz P, Zenouzi R, Schramm C, Cazzagon N, Floreani A, Liby IF, Wiestler M, Wedemeyer H, Zhou T, Strassburg CP, Rigopoulou E, Dalekos G, Narasimman M, Verhelst X, Degroote H, Vesterhus M et al. (2022)
    Impact on follow-up strategies in patients with primary sclerosing cholangitis
    Liver Int, 43 (1), 127-138
    DOI 10.1111/liv.15286, PubMed 35535655
  4. Botteri E, Hoff G, Randel KR, Holme Ø, de Lange T, Bernklev T, Aas E, Berthelsen M, Natvig E, Kirkøen B, Knudsen MD, Kvaerner AS, Schult AL, Ursin G, Jørgensen A, Berstad P (2022)
    Characteristics of nonparticipants in a randomised colorectal cancer screening trial comparing sigmoidoscopy and faecal immunochemical testing
    Int J Cancer, 151 (3), 361-371
    DOI 10.1002/ijc.34025, PubMed 35411554
  5. Brevini T, Maes M, Webb GJ, John BV, Fuchs CD, Buescher G, Wang L, Griffiths C, Brown ML, Scott WE, Pereyra-Gerber P, Gelson WTH, Brown S, Dillon S, Muraro D, Sharp J, Neary M, Box H, Tatham L, Stewart J, Curley P, Pertinez H, Forrest S, Mlcochova P, Varankar SS et al. (2022)
    FXR inhibition may protect from SARS-CoV-2 infection by reducing ACE2
    Nature, 615 (7950), 134-142
    DOI 10.1038/s41586-022-05594-0, PubMed 36470304
  6. Braadland PR, Schneider KM, Bergquist A, Molinaro A, Lövgren-Sandblom A, Henricsson M, Karlsen TH, Vesterhus M, Trautwein C, Hov JR, Marschall HU (2022)
    Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis
    JHEP Rep, 4 (11), 100561
    DOI 10.1016/j.jhepr.2022.100561, PubMed 36176935
  7. Chung BK, Øgaard J, Reims HM, Karlsen TH, Melum E (2022)
    Spatial transcriptomics identifies enriched gene expression and cell types in human liver fibrosis
    Hepatol Commun, 6 (9), 2538-2550
    DOI 10.1002/hep4.2001, PubMed 35726350
  8. Cruz R, Diz-de Almeida S, López de Heredia M, Quintela I, Ceballos FC, Pita G, Lorenzo-Salazar JM, González-Montelongo R, Gago-Domínguez M, Sevilla Porras M, Tenorio Castaño JA, Nevado J, Aguado JM, Aguilar C, Aguilera-Albesa S, Almadana V, Almoguera B, Alvarez N, Andreu-Bernabeu Á, Arana-Arri E, Arango C, Arranz MJ, Artiga MJ, Baptista-Rosas RC, Barreda-Sánchez M et al. (2022)
    Novel genes and sex differences in COVID-19 severity
    Hum Mol Genet, 31 (22), 3789-3806
    DOI 10.1093/hmg/ddac132, PubMed 35708486
  9. Degenhardt F, Ellinghaus D, Juzenas S, Lerga-Jaso J, Wendorff M, Maya-Miles D, Uellendahl-Werth F, ElAbd H, Rühlemann MC, Arora J, Özer O, Lenning OB, Myhre R, Vadla MS, Wacker EM, Wienbrandt L, Blandino Ortiz A, de Salazar A, Garrido Chercoles A, Palom A, Ruiz A, Garcia-Fernandez AE, Blanco-Grau A, Mantovani A, Zanella A et al. (2022)
    Detailed stratified GWAS analysis for severe COVID-19 in four European populations
    Hum Mol Genet, 31 (23), 3945-3966
    DOI 10.1093/hmg/ddac158, PubMed 35848942
  10. Eliasson J, Lo B, Schramm C, Chazouilleres O, Folseraas T, Beuers U, Ytting H (2022)
    Survey uncovering variations in the management of primary sclerosing cholangitis across Europe
    JHEP Rep, 4 (11), 100553
    DOI 10.1016/j.jhepr.2022.100553, PubMed 36164416
  11. Gelpi M, Vestad B, Raju SC, Hansen SH, Høgh J, Midttun Ø, Ueland PM, Ueland T, Benfield T, Kofoed KF, Hov JR, Trøseid M, Nielsen SD (2022)
    Association of the Kynurenine Pathway of Tryptophan Metabolism With Human Immunodeficiency Virus-Related Gut Microbiota Alterations and Visceral Adipose Tissue Accumulation
    J Infect Dis, 225 (11), 1948-1954
    DOI 10.1093/infdis/jiac018, PubMed 35089326
  12. Graupera I, Thiele M, Ma AT, Serra-Burriel M, Pich J, Fabrellas N, Caballeria L, de Knegt RJ, Grgurevic I, Reichert M, Roulot D, Schattenberg JM, Pericas JM, Angeli P, Tsochatzis EA, Guha IN, Garcia-Retortillo M, Morillas RM, Hernández R, Hoyo J, Fuentes M, Madir A, Juanola A, Soria A, Juan M et al. (2022)
    LiverScreen project: study protocol for screening for liver fibrosis in the general population in European countries
    BMC Public Health, 22 (1), 1385
    DOI 10.1186/s12889-022-13724-6, PubMed 35854275
  13. He MM, Lo CH, Wang K, Polychronidis G, Wang L, Zhong R, Knudsen MD, Fang Z, Song M (2022)
    Immune-Mediated Diseases Associated With Cancer Risks
    JAMA Oncol, 8 (2), 209-219
    DOI 10.1001/jamaoncol.2021.5680, PubMed 34854871
  14. Helgadottir H, Folvik G, Vesterhus M (2022)
    Improvement of cholestatic episodes in patients with benign recurrent intrahepatic cholestasis (BRIC) treated with rifampicin. A long-term follow-up
    Scand J Gastroenterol, 58 (5), 512-520
    DOI 10.1080/00365521.2022.2143725, PubMed 36369734
  15. Hov JR, Karlsen TH (2022)
    The microbiota and the gut-liver axis in primary sclerosing cholangitis
    Nat Rev Gastroenterol Hepatol, 20 (3), 135-154
    DOI 10.1038/s41575-022-00690-y, PubMed 36352157
  16. Izquierdo-Sanchez L, Lamarca A, La Casta A, Buettner S, Utpatel K, Klümpen HJ, Adeva J, Vogel A, Lleo A, Fabris L, Ponz-Sarvise M, Brustia R, Cardinale V, Braconi C, Vidili G, Jamieson NB, Macias RI, Jonas JP, Marzioni M, Hołówko W, Folseraas T, Kupčinskas J, Sparchez Z, Krawczyk M, Krupa Ł et al. (2022)
    Cholangiocarcinoma landscape in Europe: Diagnostic, prognostic and therapeutic insights from the ENSCCA Registry
    J Hepatol, 76 (5), 1109-1121
    DOI 10.1016/j.jhep.2021.12.010, PubMed 35167909
  17. Karlsen TH (2022)
    Understanding COVID-19 through genome-wide association studies
    Nat Genet, 54 (4), 368-369
    DOI 10.1038/s41588-021-00985-x, PubMed 35410380
  18. Knudsen MD, Kvaerner AS, Botteri E, Holme Ø, Hjartåker A, Song M, Thiis-Evensen E, Randel KR, Hoff G, Berstad P (2022)
    Lifestyle predictors for inconsistent participation to fecal based colorectal cancer screening
    BMC Cancer, 22 (1), 172
    DOI 10.1186/s12885-022-09287-9, PubMed 35168592
  19. Krag A, Karlsen TH (2022)
    [Not Available]
    Ugeskr Laeger, 184 (8)
    PubMed 35244013
  20. Kaarbø M, Yang M, Hov JR, Holm K, de Sousa MML, Macpherson ME, Reims HM, Kran AB, Halvorsen B, Karlsen TH, Aukrust P, Lundin KEA, Fevang B, Bjørås M, Jørgensen SF (2022)
    Duodenal inflammation in common variable immunodeficiency has altered transcriptional response to viruses
    J Allergy Clin Immunol, 151 (3), 767-777
    DOI 10.1016/j.jaci.2022.09.029, PubMed 36220400
  21. Laursen TL, Bossen L, Pihl R, Troldborg A, Sandahl TD, Hansen AG, Folserass T, Vesterhus M, Grønbæk H, Thiel S (2022)
    Highly Increased Levels of Inter-α-inhibitor Heavy Chain 4 (ITIH4) in Autoimmune Cholestatic Liver Diseases
    J Clin Transl Hepatol, 10 (5), 796-802
    DOI 10.14218/JCTH.2021.00515, PubMed 36304505
  22. Lei L, Bruneau A, El Mourabit H, Guégan J, Folseraas T, Lemoinne S, Karlsen TH, Hoareau B, Morichon R, Gonzalez-Sanchez E, Goumard C, Ratziu V, Charbord P, Gautheron J, Tacke F, Jaffredo T, Cadoret A, Housset C (2022)
    Portal fibroblasts with mesenchymal stem cell features form a reservoir of proliferative myofibroblasts in liver fibrosis
    Hepatology, 76 (5), 1360-1375
    DOI 10.1002/hep.32456, PubMed 35278227
  23. Meyer-Myklestad MH, Medhus AW, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Stiksrud B, Trøseid M, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Reikvam DH (2022)
    Human Immunodeficiency Virus-Infected Immunological Nonresponders Have Colon-Restricted Gut Mucosal Immune Dysfunction
    J Infect Dis, 225 (4), 661-674
    DOI 10.1093/infdis/jiaa714, PubMed 33216130
  24. Meyer-Myklestad MH, Medhus AW, Stiksrud B, Lorvik KB, Seljeflot I, Hansen SH, Holm K, Hov JR, Kvale D, Dyrhol-Riise AM, Kummen M, Trøseid M, Reikvam DH (2022)
    Probiotics to HIV-Infected Immunological Nonresponders: Altered Mucosal Immunity and Microbial Diversity Restricted to Ileum
    J Acquir Immune Defic Syndr, 89 (1), 77-86
    DOI 10.1097/QAI.0000000000002817, PubMed 34878437
  25. Nooijen LE, Banales JM, de Boer MT, Braconi C, Folseraas T, Forner A, Holowko W, Hoogwater FJH, Klümpen HJ, Groot Koerkamp B, Lamarca A, La Casta A, López-López F, Izquierdo-Sánchez L, Scheiter A, Utpatel K, Swijnenburg RJ, Kazemier G, Erdmann JI,   ENSCCA Group (2022)
    Impact of Positive Lymph Nodes and Resection Margin Status on the Overall Survival of Patients with Resected Perihilar Cholangiocarcinoma: The ENSCCA Registry
    Cancers (Basel), 14 (10)
    DOI 10.3390/cancers14102389, PubMed 35625993
  26. Singh Y, Jons WA, Eaton JE, Vesterhus M, Karlsen T, Bjoerk I, Abildgaard A, Jorgensen KK, Folseraas T, Little D, Gulamhusein AF, Petrovic K, Negard A, Conte GM, Sobek JD, Jagtap J, Venkatesh SK, Gores GJ, LaRusso NF, Lazaridis KN, Erickson BJ (2022)
    Algebraic topology-based machine learning using MRI predicts outcomes in primary sclerosing cholangitis
    Eur Radiol Exp, 6 (1), 58
    DOI 10.1186/s41747-022-00312-x, PubMed 36396865
  27. Storm-Larsen C, Hande LN, Kummen M, Thunhaug H, Vestad B, Hansen SH, Hovland A, Trøseid M, Lappegård KT, Hov JR (2022)
    Reduced gut microbial diversity in familial hypercholesterolemia with no effect of omega-3 polyunsaturated fatty acids intervention - a pilot trial
    Scand J Clin Lab Invest, 82 (5), 363-370
    DOI 10.1080/00365513.2022.2102540, PubMed 35913798
  28. Stø K, Valeur J, Ueland T, Malmstrøm GH, Bjerkeli V, Trøseid M, Hov JR, Holm K, Vestad B, Halvorsen B, Skjelland M, Skagen KR (2022)
    Fecal level of butyric acid, a microbiome-derived metabolite, is increased in patients with severe carotid atherosclerosis
    Sci Rep, 12 (1), 22378
    DOI 10.1038/s41598-022-26759-x, PubMed 36572703
  29. Tran TT, Vaage EB, Mehta A, Chopra A, Tietze L, Kolderup A, Anthi A, König M, Nygaard G, Lind A, Müller F, Nissen-Meyer LS, Magnus P, Trogstad L, Mjaaland S, Søraas A, Midtvedt K, Åsberg A, Barratt-Due A, Medhus AW, Høivik ML, Lundin K, Karlsen RF, Dahle R, Danielsson K et al. (2022)
    Titers of antibodies against ancestral SARS-CoV-2 correlate with levels of neutralizing antibodies to multiple variants
    NPJ Vaccines, 7 (1), 174
    DOI 10.1038/s41541-022-00586-7, PubMed 36585405
  30. Tønnessen TC, Melleby AO, Hauge-Iversen IM, Espe EKS, Ahmed MS, Ueland T, Haavardsholm EA, Atkinson SM, Melum E, Attramadal H, Sjaastad I, Vinge LE (2022)
    Impact of delayed type hypersensitivity arthritis on development of heart failure by aortic constriction in mice
    PLoS One, 17 (1), e0262821
    DOI 10.1371/journal.pone.0262821, PubMed 35077491
  31. Valestrand L, Zheng F, Hansen SH, Øgaard J, Hov JR, Björkström NK, Karlsen TH, Jiang X, Melum E (2022)
    Bile from Patients with Primary Sclerosing Cholangitis Contains Mucosal-Associated Invariant T-Cell Antigens
    Am J Pathol, 192 (4), 629-641
    DOI 10.1016/j.ajpath.2021.12.008, PubMed 35063408
  32. van der Meer D, Gurholt TP, Sønderby IE, Shadrin AA, Hindley G, Rahman Z, de Lange AG, Frei O, Leinhard OD, Linge J, Simon R, Beck D, Westlye LT, Halvorsen S, Dale AM, Karlsen TH, Kaufmann T, Andreassen OA (2022)
    The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
    Commun Biol, 5 (1), 1271
    DOI 10.1038/s42003-022-04237-4, PubMed 36402844
  33. Vestad B, Ueland T, Lerum TV, Dahl TB, Holm K, Barratt-Due A, Kåsine T, Dyrhol-Riise AM, Stiksrud B, Tonby K, Hoel H, Olsen IC, Henriksen KN, Tveita A, Manotheepan R, Haugli M, Eiken R, Berg Å, Halvorsen B, Lekva T, Ranheim T, Michelsen AE, Kildal AB, Johannessen A, Thoresen L et al. (2022)
    Respiratory dysfunction three months after severe COVID-19 is associated with gut microbiota alterations
    J Intern Med, 291 (6), 801-812
    DOI 10.1111/joim.13458, PubMed 35212063
  34. Vesterhus M (2022)
    [Good TIPS for severe liver disease]
    Tidsskr Nor Laegeforen, 142 (14)
    DOI 10.4045/tidsskr.22.0585, PubMed 36226424
  35. Vesterhus M, Jørgensen KK, Frigstad SO, Haukeland JW, Karlsen TH (2022)
    [We need a new strategy for liver disease]
    Tidsskr Nor Laegeforen, 142 (3)
    DOI 10.4045/tidsskr.21.0892, PubMed 35170917
  36. Wang K, Ma W, Hu Y, Knudsen MD, Nguyen LH, Wu K, Ng K, Wang M, Ogino S, Sun Q, Giovannucci EL, Chan AT, Song M (2022)
    Endoscopic Screening and Risk of Colorectal Cancer according to Type 2 Diabetes Status
    Cancer Prev Res (Phila), 15 (12), 847-856
    DOI 10.1158/1940-6207.CAPR-22-0305, PubMed 36049216
  37. Wang L, Knudsen MD, Lo CH, Wang K, He M, Polychronidis G, Hang D, He X, Zhong R, Wu K, Chan AT, Ogino S, Giovannucci EL, Song M (2022)
    Adherence to a healthy lifestyle in relation to colorectal cancer incidence and all-cause mortality after endoscopic polypectomy: A prospective study in three U.S. cohorts
    Int J Cancer, 151 (9), 1523-1534
    DOI 10.1002/ijc.34176, PubMed 35716133
  38. Yu J, Refsum E, Helsingen LM, Folseraas T, Ploner A, Wieszczy P, Barua I, Jodal HC, Melum E, Løberg M, Blom J, Bretthauer M, Adami HO, Kalager M, Ye W (2022)
    Risk of hepato-pancreato-biliary cancer is increased by primary sclerosing cholangitis in patients with inflammatory bowel disease: A population-based cohort study
    United European Gastroenterol J, 10 (2), 212-224
    DOI 10.1002/ueg2.12204, PubMed 35107865

Publications 2021

  1. Aune D, Sen A, Norat T, Riboli E, Folseraas T (2021)
    Primary sclerosing cholangitis and the risk of cancer, cardiovascular disease, and all-cause mortality: a systematic review and meta-analysis of cohort studies
    Sci Rep, 11 (1), 10646
    DOI 10.1038/s41598-021-90175-w, PubMed 34017024
  2. Awoyemi A, Mayerhofer C, Felix AS, Hov JR, Moscavitch SD, Lappegård KT, Hovland A, Halvorsen S, Halvorsen B, Gregersen I, Svardal A, Berge RK, Hansen SH, Götz A, Holm K, Aukrust P, Åkra S, Seljeflot I, Solheim S, Lorenzo A, Gullestad L, Trøseid M, Broch K (2021)
    Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial
    EBioMedicine, 70, 103511
    DOI 10.1016/j.ebiom.2021.103511, PubMed 34329947
  3. Bossen L, Vesterhus M, Hov JR, Färkkilä M, Rosenberg WM, Møller HJ, Boberg KM, Karlsen TH, Grønbæk H (2021)
    Circulating Macrophage Activation Markers Predict Transplant-Free Survival in Patients With Primary Sclerosing Cholangitis
    Clin Transl Gastroenterol, 12 (3), e00315
    DOI 10.14309/ctg.0000000000000315, PubMed 33646203
  4. COVID-19 Host Genetics Initiative (2021)
    Mapping the human genetic architecture of COVID-19
    Nature, 600 (7889), 472-477
    DOI 10.1038/s41586-021-03767-x, PubMed 34237774
  5. Degenhardt F, Mayr G, Wendorff M, Boucher G, Ellinghaus E, Ellinghaus D, ElAbd H, Rosati E, Hübenthal M, Juzenas S, Abedian S, Vahedi H, Thelma BK, Yang SK, Ye BD, Cheon JH, Datta LW, Daryani NE, Ellul P, Esaki M, Fuyuno Y, McGovern DPB, Haritunians T, Hong M, Juyal G et al. (2021)
    Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations
    Hum Mol Genet, 30 (5), 356-369
    DOI 10.1093/hmg/ddab017, PubMed 33555323
  6. Dhillon AK, Rupp C, Bergquist A, Voitl R, Folseraas T, Trøseid M, Midttun Ø, Ueland PM, Karlsen TH, Vesterhus M, Kummen M, Hov JR (2021)
    Associations of neopterin and kynurenine-tryptophan ratio with survival in primary sclerosing cholangitis
    Scand J Gastroenterol, 56 (4), 443-452
    DOI 10.1080/00365521.2021.1880627, PubMed 33583308
  7. Fossdal G, Mjelle AB, Wiencke K, Bjørk I, Gilja OH, Folseraas T, Karlsen TH, Rosenberg W, Giil LM, Vesterhus M (2021)
    Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF
    JHEP Rep, 3 (5), 100328
    DOI 10.1016/j.jhepr.2021.100328, PubMed 34485881
  8. Hausken J, Haugaa H, Hagness M, Line PD, Melum E, Tønnessen TI (2021)
    Thoracic Epidural Analgesia for Postoperative Pain Management in Liver Transplantation: A 10-year Study on 685 Liver Transplant Recipients
    Transplant Direct, 7 (2), e648
    DOI 10.1097/TXD.0000000000001101, PubMed 33437863
  9. Jiang X, Bergquist A, Löscher BS, Venkatesh G, Mold JE, Holm K, Laerdahl JK, Skånland SS, Maleki KT, Cornillet M, Taskén K, Franke A, Karlsen TH, Björkström NK, Melum E (2021)
    A heterozygous germline CD100 mutation in a family with primary sclerosing cholangitis
    Sci Transl Med, 13 (582)
    DOI 10.1126/scitranslmed.abb0036, PubMed 33627483
  10. Jiang X, Melum E (2021)
    The Role of Natural Killer Cells in Nonalcoholic Steatohepatitis: An Ongoing Debate
    Cell Mol Gastroenterol Hepatol, 13 (1), 348-349
    DOI 10.1016/j.jcmgh.2021.10.006, PubMed 34740615
  11. Karlsen TH, Sheron N, Zelber-Sagi S, Carrieri P, Dusheiko G, Bugianesi E, Pryke R, Hutchinson SJ, Sangro B, Martin NK, Cecchini M, Dirac MA, Belloni A, Serra-Burriel M, Ponsioen CY, Sheena B, Lerouge A, Devaux M, Scott N, Hellard M, Verkade HJ, Sturm E, Marchesini G, Yki-Järvinen H, Byrne CD et al. (2021)
    The EASL-Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality
    Lancet, 399 (10319), 61-116
    DOI 10.1016/S0140-6736(21)01701-3, PubMed 34863359
  12. Karlsen TR, Kong XY, Holm S, Quiles-Jiménez A, Dahl TB, Yang K, Sagen EL, Skarpengland T, S Øgaard JD, Holm K, Vestad B, Olsen MB, Aukrust P, Bjørås M, Hov JR, Halvorsen B, Gregersen I (2021)
    NEIL3-deficiency increases gut permeability and contributes to a pro-atherogenic metabolic phenotype
    Sci Rep, 11 (1), 19749
    DOI 10.1038/s41598-021-98820-0, PubMed 34611194
  13. Knudsen MD, Wang L, Wang K, Wu K, Ogino S, Chan AT, Giovannucci E, Song M (2021)
    Changes in Lifestyle Factors After Endoscopic Screening: A Prospective Study in the United States
    Clin Gastroenterol Hepatol, 20 (6), e1240-e1249
    DOI 10.1016/j.cgh.2021.07.014, PubMed 34256146
  14. Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW (2021)
    Hepatology, 74 (2), 1129-1131
    DOI 10.1002/hep.31740, PubMed 33550618
  15. Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW (2021)
    Letter to the Editor: Does Multiple Intrahepatic Cholangiocarcinoma Worsen Prognosis as "M1" Stage? REPLY
    Hepatology, 74 (2), 1129-1131
    DOI 10.1002/hep.31740
  16. Lamarca A, Santos-Laso A, Utpatel K, La Casta A, Stock S, Forner A, Adeva J, Folseraas T, Fabris L, Macias RIR, Krawczyk M, Krawczyk M, Cardinale V, Braconi C, Alvaro D, Evert M, Banales JM, Valle JW, Group: on behalf of the European Network for the Study of Cholangiocarcinoma (ENS-CCA) (2021)
    Liver Metastases of Intrahepatic Cholangiocarcinoma: Implications for an Updated Staging System
    Hepatology, 73 (6), 2311-2325
    DOI 10.1002/hep.31598, PubMed 33073396
  17. Lissing M, Nowak G, Adam R, Karam V, Boyd A, Gouya L, Meersseman W, Melum E, Ołdakowska-Jedynak U, Reiter FP, Colmenero J, Sanchez R, Herden U, Langendonk J, Ventura P, Isoniemi H, Boillot O, Braun F, Perrodin S, Mowlem E, Wahlin S, European Liver and Intestine Transplant Association (2021)
    Liver Transplantation for Acute Intermittent Porphyria
    Liver Transpl, 27 (4), 491-501
    DOI 10.1002/lt.25959, PubMed 33259654
  18. Mousa OY, Juran BD, McCauley BM, Vesterhus MN, Folseraas T, Turgeon CT, Ali AH, Schlicht EM, Atkinson EJ, Hu C, Harnois D, Carey EJ, Gossard AA, Oglesbee D, Eaton JE, LaRusso NF, Gores GJ, Karlsen TH, Lazaridis KN (2021)
    Bile Acid Profiles in Primary Sclerosing Cholangitis and Their Ability to Predict Hepatic Decompensation
    Hepatology, 74 (1), 281-295
    DOI 10.1002/hep.31652, PubMed 33226645
  19. Nakanishi T, Pigazzini S, Degenhardt F, Cordioli M, Butler-Laporte G, Maya-Miles D, Bujanda L, Bouysran Y, Niemi ME, Palom A, Ellinghaus D, Khan A, Martínez-Bueno M, Rolker S, Amitrano S, Roade Tato L, Fava F, FinnGen, COVID-19 Host Genetics Initiative (HGI), Spinner CD, Prati D, Bernardo D, Garcia F, Darcis G, Fernández-Cadenas I et al. (2021)
    Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
    J Clin Invest, 131 (23)
    DOI 10.1172/JCI152386, PubMed 34597274
  20. Nakanishi T, Pigazzini S, Degenhardt F, Cordioli M, Butler-Laporte G, Maya-Miles D, Nafría-Jiménez B, Bouysran Y, Niemi M, Palom A, Ellinghaus D, Khan A, Martínez-Bueno M, Rolker S, Amitano S, Tato LR, FinnGen, The COVID-19 Host Genetics Initiative, Fava F, Spinner CD, Prati D, Bernardo D, Garcia F, Darcis G, Fernández-Cadenas I, Holter JC et al. (2021)
    Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality
    DOI 10.1101/2021.03.07.21252875, PubMed 33758887
  21. Pagano E, Elias JE, Schneditz G, Saveljeva S, Holland LM, Borrelli F, Karlsen TH, Kaser A, Kaneider NC (2021)
    Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment
    Gut, 71 (3), 509-520
    DOI 10.1136/gutjnl-2020-323363, PubMed 33758004
  22. Polychronidis G, Wang K, Lo CH, Wang L, He M, Knudsen MD, Wu K, Joshi AD, Ogino S, Giovannucci EL, Chan AT, Song M (2021)
    Gallstone Disease and Risk of Conventional Adenomas and Serrated Polyps: A Prospective Study
    Cancer Epidemiol Biomarkers Prev, 30 (12), 2346-2349
    DOI 10.1158/1055-9965.EPI-21-0515, PubMed 34620626
  23. Reich M, Spomer L, Klindt C, Fuchs K, Stindt J, Deutschmann K, Höhne J, Liaskou E, Hov JR, Karlsen TH, Beuers U, Verheij J, Ferreira-Gonzalez S, Hirschfield G, Forbes SJ, Schramm C, Esposito I, Nierhoff D, Fickert P, Fuchs CD, Trauner M, García-Beccaria M, Gabernet G, Nahnsen S, Mallm JP et al. (2021)
    Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis
    J Hepatol, 75 (3), 634-646
    DOI 10.1016/j.jhep.2021.03.029, PubMed 33872692
  24. Sampaziotis F, Muraro D, Tysoe OC, Sawiak S, Beach TE, Godfrey EM, Upponi SS, Brevini T, Wesley BT, Garcia-Bernardo J, Mahbubani K, Canu G, Gieseck R, Berntsen NL, Mulcahy VL, Crick K, Fear C, Robinson S, Swift L, Gambardella L, Bargehr J, Ortmann D, Brown SE, Osnato A, Murphy MP et al. (2021)
    Cholangiocyte organoids can repair bile ducts after transplantation in the human liver
    Science, 371 (6531), 839-846
    DOI 10.1126/science.aaz6964, PubMed 33602855
  25. Schneider KM, Candels LS, Hov JR, Myllys M, Hassan R, Schneider CV, Wahlström A, Mohs A, Zühlke S, Liao L, Elfers C, Kilic K, Henricsson M, Molinaro A, Hatting M, Zaza A, Drasdo D, Frissen M, Devlin AS, Gálvez EJC, Strowig T, Karlsen TH, Hengstler JG, Marschall HU, Ghallab A et al. (2021)
    Gut microbiota depletion exacerbates cholestatic liver injury via loss of FXR signalling
    Nat Metab, 3 (9), 1228-1241
    DOI 10.1038/s42255-021-00452-1, PubMed 34552267
  26. Skarpengland T, Macpherson ME, Hov JR, Kong XY, Bohov P, Halvorsen B, Fevang B, Berge RK, Aukrust P, Jørgensen SF (2021)
    Altered Plasma Fatty Acids Associate with Gut Microbial Composition in Common Variable Immunodeficiency
    J Clin Immunol, 42 (1), 146-157
    DOI 10.1007/s10875-021-01146-9, PubMed 34669143
  27. Skaarud KJ, Hov JR, Hansen SH, Kummen M, Valeur J, Seljeflot I, Bye A, Paulsen V, Lundin KEA, Trøseid M, Tjønnfjord GE, Iversen PO (2021)
    Mortality and microbial diversity after allogeneic hematopoietic stem cell transplantation: secondary analysis of a randomized nutritional intervention trial
    Sci Rep, 11 (1), 11593
    DOI 10.1038/s41598-021-90976-z, PubMed 34078971
  28. Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
    Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
    Hepatology, 75 (1), 59-73
    DOI 10.1002/hep.32125, PubMed 34435693
  29. Vestad B, Nyman TA, Hove-Skovsgaard M, Stensland M, Hoel H, Trøseid AS, Aspelin T, Aass HCD, Puhka M, Hov JR, Nielsen SD, Øvstebø R, Trøseid M (2021)
    Plasma extracellular vesicles in people living with HIV and type 2 diabetes are related to microbial translocation and cardiovascular risk
    Sci Rep, 11 (1), 21936
    DOI 10.1038/s41598-021-01334-y, PubMed 34754007
  30. Vesterhus M, Wiencke K, Haukeland JW, Frigstad SO, Karlsen LN, Jørgensen KK, Folseraas T (2021)
    [Diagnosis and treatment of autoimmune hepatitis]
    Tidsskr Nor Laegeforen, 141 (10)
    DOI 10.4045/tidsskr.20.1045, PubMed 34182737
  31. Zimmer CL, Filipovic I, Cornillet M, O'Rourke CJ, Berglin L, Jansson H, Sun D, Strauss O, Hertwig L, Johansson H, von Seth E, Sparrelid E, Dias J, Glaumann H, Melum E, Ellis EC, Sandberg JK, Andersen JB, Bergquist A, Björkström NK (2021)
    Mucosal-associated invariant T-cell tumor infiltration predicts long-term survival in cholangiocarcinoma
    Hepatology, 75 (5), 1154-1168
    DOI 10.1002/hep.32222, PubMed 34719787
  32. Zimmer CL, von Seth E, Buggert M, Strauss O, Hertwig L, Nguyen S, Wong AYW, Zotter C, Berglin L, Michaëlsson J, Hansson MR, Arnelo U, Sparrelid E, Ellis ECS, Söderholm JD, Keita ÅV, Holm K, Özenci V, Hov JR, Mold JE, Cornillet M, Ponzetta A, Bergquist A, Björkström NK (2021)
    A biliary immune landscape map of primary sclerosing cholangitis reveals a dominant network of neutrophils and tissue-resident T cells
    Sci Transl Med, 13 (599)
    DOI 10.1126/scitranslmed.abb3107, PubMed 34162753

Publications 2020

  1. Deeb M, Karlsen TH, Hirschfield GM (2020)
    The 6 C's of primary sclerosing cholangitis
    J Hepatol, 73 (5), 1255-1256
    DOI 10.1016/j.jhep.2020.06.033, PubMed 32649970
  2. Derer S, Brethack AK, Pietsch C, Jendrek ST, Nitzsche T, Bokemeyer A, Hov JR, Schäffler H, Bettenworth D, Grassl GA, Sina C (2020)
    Inflammatory Bowel Disease-associated GP2 Autoantibodies Inhibit Mucosal Immune Response to Adherent-invasive Bacteria
    Inflamm Bowel Dis, 26 (12), 1856-1868
    DOI 10.1093/ibd/izaa069, PubMed 32304568
  3. Fretheim H, Chung BK, Didriksen H, Bækkevold ES, Midtvedt Ø, Brunborg C, Holm K, Valeur J, Tennøe AH, Garen T, Midtvedt T, Trøseid M, Zarè H, Lund MB, Hov JR, Lundin KEA, Molberg Ø, Hoffmann-Vold AM (2020)
    Fecal microbiota transplantation in systemic sclerosis: A double-blind, placebo-controlled randomized pilot trial
    PLoS One, 15 (5), e0232739
    DOI 10.1371/journal.pone.0232739, PubMed 32437393
  4. Gelpi M, Vestad B, Hansen SH, Holm K, Drivsholm N, Goetz A, Kirkby NS, Lindegaard B, Lebech AM, Hoel H, Michelsen AE, Ueland T, Gerstoft J, Lundgren J, Hov JR, Nielsen SD, Trøseid M (2020)
    Impact of Human Immunodeficiency Virus-Related Gut Microbiota Alterations on Metabolic Comorbid Conditions
    Clin Infect Dis, 71 (8), e359-e367
    DOI 10.1093/cid/ciz1235, PubMed 31894240
  5. Goeppert B, Folseraas T, Roessler S, Kloor M, Volckmar AL, Endris V, Buchhalter I, Stenzinger A, Grzyb K, Grimsrud MM, Gornicka B, von Seth E, Reynolds GM, Franke A, Gotthardt DN, Mehrabi A, Cheung A, Verheij J, Arola J, Mäkisalo H, Eide TJ, Weidemann S, Cheville JC, Mazza G, Hirschfield GM et al. (2020)
    Genomic Characterization of Cholangiocarcinoma in Primary Sclerosing Cholangitis Reveals Therapeutic Opportunities
    Hepatology, 72 (4), 1253-1266
    DOI 10.1002/hep.31110, PubMed 31925805
  6. He MM, Fang Z, Hang D, Wang F, Polychronidis G, Wang L, Lo CH, Wang K, Zhong R, Knudsen MD, Smith SG, Xu RH, Song M (2020)
    Circulating liver function markers and colorectal cancer risk: A prospective cohort study in the UK Biobank
    Int J Cancer, 148 (8), 1867-1878
    DOI 10.1002/ijc.33351, PubMed 33091956
  7. Knudsen MD, Botteri E, Holme Ø, Hjartåker A, Song M, Thiis-Evensen E, Norvard ER, Schult AL, Randel KR, Hoff G, Berstad P (2020)
    Association between lifestyle and site-specific advanced colorectal lesions in screening with faecal immunochemical test and sigmoidoscopy
    Dig Liver Dis, 53 (3), 353-359
    DOI 10.1016/j.dld.2020.11.021, PubMed 33309513
  8. Kovaleva TF, Maksimova NS, Pchelin PV, Pershin VI, Tkachenko NM, Gainullin MR, Mukhina IV (2020)
    A New Cofilin-Dependent Mechanism for the Regulation of Brain Mitochondria Biogenesis and Degradation
    Sovrem Tekhnologii Med, 12 (1), 6-13
    DOI 10.17691/stm2020.12.1.01, PubMed 34513032
  9. Kummen M, Solberg OG, Storm-Larsen C, Holm K, Ragnarsson A, Trøseid M, Vestad B, Skårdal R, Yndestad A, Ueland T, Svardal A, Berge RK, Seljeflot I, Gullestad L, Karlsen TH, Aaberge L, Aukrust P, Hov JR (2020)
    Rosuvastatin alters the genetic composition of the human gut microbiome
    Sci Rep, 10 (1), 5397
    DOI 10.1038/s41598-020-62261-y, PubMed 32214138
  10. Kummen M, Thingholm LB, Rühlemann MC, Holm K, Hansen SH, Moitinho-Silva L, Liwinski T, Zenouzi R, Storm-Larsen C, Midttun Ø, McCann A, Ueland PM, Høivik ML, Vesterhus M, Trøseid M, Laudes M, Lieb W, Karlsen TH, Bang C, Schramm C, Franke A, Hov JR (2020)
    Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis
    Gastroenterology, 160 (5), 1784-1798.e0
    DOI 10.1053/j.gastro.2020.12.058, PubMed 33387530
  11. Lapitz A, Arbelaiz A, O'Rourke CJ, Lavin JL, Casta A, Ibarra C, Jimeno JP, Santos-Laso A, Izquierdo-Sanchez L, Krawczyk M, Perugorria MJ, Jimenez-Aguero R, Sanchez-Campos A, Riaño I, Gónzalez E, Lammert F, Marzioni M, Macias RIR, Marin JJG, Karlsen TH, Bujanda L, Falcón-Pérez JM, Andersen JB, Aransay AM, Rodrigues PM et al. (2020)
    Patients with Cholangiocarcinoma Present Specific RNA Profiles in Serum and Urine Extracellular Vesicles Mirroring the Tumor Expression: Novel Liquid Biopsy Biomarkers for Disease Diagnosis
    Cells, 9 (3)
    DOI 10.3390/cells9030721, PubMed 32183400
  12. Lo CH, Kwon S, Wang L, Polychronidis G, Knudsen MD, Zhong R, Cao Y, Wu K, Ogino S, Giovannucci EL, Chan AT, Song M (2020)
    Periodontal disease, tooth loss, and risk of oesophageal and gastric adenocarcinoma: a prospective study
    Gut, 70 (3), 620-621
    DOI 10.1136/gutjnl-2020-321949, PubMed 32690603
  13. Lohse AW, Sebode M, Jørgensen MH, Ytting H, Karlsen TH, Kelly D, Manns MP, Vesterhus M, European Reference Network on Hepatological Diseases (ERN RARE-LIVER), International Autoimmune Hepatitis Group (IAIHG) (2020)
    Second-line and third-line therapy for autoimmune hepatitis: A position statement from the European Reference Network on Hepatological Diseases and the International Autoimmune Hepatitis Group
    J Hepatol, 73 (6), 1496-1506
    DOI 10.1016/j.jhep.2020.07.023, PubMed 32707224
  14. Lohse AW, Sebode M, Vesterhus M (2020)
    Reply to: "Both tacrolimus and mycophenylate mophetil should be considered second-line therapy for autoimmune hepatitis"
    J Hepatol, 74 (3), 755-756
    DOI 10.1016/j.jhep.2020.11.031, PubMed 33309116
  15. Louwe MC, Olsen MB, Kaasbøll OJ, Yang K, Fosshaug LE, Alfsnes K, Øgaard JDS, Rashidi A, Skulberg VM, Yang M, de Miranda Fonseca D, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjørås M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A (2020)
    Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
    JACC Basic Transl Sci, 5 (12), 1210-1224
    DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377
  16. Macpherson ME, Hov JR, Ueland T, Dahl TB, Kummen M, Otterdal K, Holm K, Berge RK, Mollnes TE, Trøseid M, Halvorsen B, Aukrust P, Fevang B, Jørgensen SF (2020)
    Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
    Front Immunol, 11, 574500
    DOI 10.3389/fimmu.2020.574500, PubMed 33042155
  17. Mayerhofer CCK, Kummen M, Holm K, Broch K, Awoyemi A, Vestad B, Storm-Larsen C, Seljeflot I, Ueland T, Bohov P, Berge RK, Svardal A, Gullestad L, Yndestad A, Aukrust P, Hov JR, Trøseid M (2020)
    Low fibre intake is associated with gut microbiota alterations in chronic heart failure
    ESC Heart Fail, 7 (2), 456-466
    DOI 10.1002/ehf2.12596, PubMed 31978943
  18. Mjelle AB, Fossdal G, Gilja OH, Vesterhus M (2020)
    Liver Elastography in Primary Sclerosing Cholangitis Patients Using Three Different Scanner Systems
    Ultrasound Med Biol, 46 (8), 1854-1864
    DOI 10.1016/j.ultrasmedbio.2020.03.025, PubMed 32507342
  19. Severe Covid-19 GWAS Group, Ellinghaus D, Degenhardt F, Bujanda L, Buti M, Albillos A, Invernizzi P, Fernández J, Prati D, Baselli G, Asselta R, Grimsrud MM, Milani C, Aziz F, Kässens J, May S, Wendorff M, Wienbrandt L, Uellendahl-Werth F, Zheng T, Yi X, de Pablo R, Chercoles AG, Palom A, Garcia-Fernandez AE et al. (2020)
    Genomewide Association Study of Severe Covid-19 with Respiratory Failure
    N Engl J Med, 383 (16), 1522-1534
    DOI 10.1056/NEJMoa2020283, PubMed 32558485
  20. Sokolova M, Yang K, Hansen SH, Louwe MC, Kummen M, Hov JER, Sjaastad I, Berge RK, Halvorsen B, Aukrust P, Yndestad A, Ranheim T (2020)
    NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet
    Sci Rep, 10 (1), 21006
    DOI 10.1038/s41598-020-76497-1, PubMed 33273482
  21. Taraldsen V, Tomasgard S, Rudlang M, Gilja O, Vesterhus M, Mjelle A (2020)
    Point Shear Wave Elastography and the Effect of Physical Exercise, Alcohol Consumption, and Respiration in Healthy Adults
    Ultrasound Int Open, 6 (3), E54-E61
    DOI 10.1055/a-1298-9642, PubMed 33305164
  22. Taraldsen V, Tomasgard S, Rudlang MT, Gilja OH, Vesterhus M, Mjelle AB (2020)
    Correction: Point Shear Wave Elastography and the Effect of Physical Exercise, Alcohol Consumption, and Respiration in Healthy Adults
    Ultrasound Int Open, 6 (3), E66
    DOI 10.1055/a-1340-1260, PubMed 33426423
  23. Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ et al. (2020)
    Whole-genome sequencing of a sporadic primary immunodeficiency cohort
    Nature, 583 (7814), 90-95
    DOI 10.1038/s41586-020-2265-1, PubMed 32499645
  24. Thaventhiran JED, Lango Allen H, Burren OS, Rae W, Greene D, Staples E, Zhang Z, Farmery JHR, Simeoni I, Rivers E, Maimaris J, Penkett CJ, Stephens J, Deevi SVV, Sanchis-Juan A, Gleadall NS, Thomas MJ, Sargur RB, Gordins P, Baxendale HE, Brown M, Tuijnenburg P, Worth A, Hanson S, Linger RJ et al. (2020)
    Publisher Correction: Whole-genome sequencing of a sporadic primary immunodeficiency cohort
    Nature, 584 (7819), E2
    DOI 10.1038/s41586-020-2556-6, PubMed 32678341
  25. Trimboli P, Castellana M, Virili C, Havre RF, Bini F, Marinozzi F, D'Ambrosio F, Giorgino F, Giovanella L, Prosch H, Grani G, Radzina M, Cantisani V (2020)
    Performance of contrast-enhanced ultrasound (CEUS) in assessing thyroid nodules: a systematic review and meta-analysis using histological standard of reference
    Radiol Med, 125 (4), 406-415
    DOI 10.1007/s11547-019-01129-2, PubMed 31970579
  26. Valestrand L, Berntsen NL, Zheng F, Schrumpf E, Hansen SH, Karlsen TH, Blumberg RS, Hov JR, Jiang X, Melum E (2020)
    Lipid antigens in bile from patients with chronic liver diseases activate natural killer T cells
    Clin Exp Immunol, 203 (2), 304-314
    DOI 10.1111/cei.13541, PubMed 33089489
  27. Vedeld HM, Folseraas T, Lind GE (2020)
    Detecting cholangiocarcinoma in patients with primary sclerosing cholangitis - The promise of DNA methylation and molecular biomarkers
    JHEP Rep, 2 (5), 100143
    DOI 10.1016/j.jhepr.2020.100143, PubMed 32939446
  28. Vesterhus M, Karlsen TH (2020)
    Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities
    J Gastroenterol, 55 (6), 588-614
    DOI 10.1007/s00535-020-01681-z, PubMed 32222826
  29. Vesterhus M, Nielsen MJ, Hov JR, Saffioti F, Manon-Jensen T, Leeming DJ, Moum B, Boberg KM, Pinzani M, Karlsen TH, Karsdal MA, Thorburn D (2020)
    Comprehensive assessment of ECM turnover using serum biomarkers establishes PBC as a high-turnover autoimmune liver disease
    JHEP Rep, 3 (1), 100178
    DOI 10.1016/j.jhepr.2020.100178, PubMed 33225252

Publications 2019

  1. Balashova A, Pershin V, Zaborskaya O, Tkachenko N, Mironov A, Guryev E, Kurbatov L, Gainullin M, Mukhina I (2019)
    Enzymatic Digestion of Hyaluronan-Based Brain Extracellular Matrix in vivo Can Induce Seizures in Neonatal Mice
    Front Neurosci, 13, 1033
    DOI 10.3389/fnins.2019.01033, PubMed 31632233
  2. Dhillon AK, Kremer AE, Kummen M, Boberg KM, Elferink RPO, Karlsen TH, Beuers U, Vesterhus M, Hov JR (2019)
    Autotaxin activity predicts transplant-free survival in primary sclerosing cholangitis
    Sci Rep, 9 (1), 8450
    DOI 10.1038/s41598-019-44762-7, PubMed 31186435
  3. Goode EC, Clark AB, Mells GF, Srivastava B, Spiess K, Gelson WTH, Trivedi PJ, Lynch KD, Castren E, Vesterhus MN, Karlsen TH, Ji SG, Anderson CA, Thorburn D, Hudson M, Heneghan MA, Aldersley MA, Bathgate A, Sandford RN, Alexander GJ, Chapman RW, Walmsley M, UK-PSC Consortium, Hirschfield GM, Rushbrook SM (2019)
    Factors Associated With Outcomes of Patients With Primary Sclerosing Cholangitis and Development and Validation of a Risk Scoring System
    Hepatology, 69 (5), 2120-2135
    DOI 10.1002/hep.30479, PubMed 30566748
  4. Grimsrud MM, Brekke M, Syse VL, Vallersnes OM (2019)
    Acute poisoning related to the recreational use of prescription drugs: an observational study from Oslo, Norway
    BMC Emerg Med, 19 (1), 55
    DOI 10.1186/s12873-019-0271-0, PubMed 31615421
  5. Grimsrud MM, Folseraas T (2019)
    Pathogenesis, diagnosis and treatment of premalignant and malignant stages of cholangiocarcinoma in primary sclerosing cholangitis
    Liver Int, 39 (12), 2230-2237
    DOI 10.1111/liv.14180, PubMed 31216595
  6. Hole MJ (2019)
    [Fulminant bureaucratitis in junior doctors’ titles]
    Tidsskr Nor Laegeforen, 139 (7)
    DOI 10.4045/tidsskr.19.0176, PubMed 30969047
  7. Hov JR (2019)
    Editorial: proton pump inhibition - microbial complications beyond dysbiosis
    Aliment Pharmacol Ther, 50 (8), 962-963
    DOI 10.1111/apt.15495, PubMed 31591776
  8. Jørgensen SF, Holm K, Macpherson ME, Storm-Larsen C, Kummen M, Fevang B, Aukrust P, Hov JR (2019)
    Selective IgA deficiency in humans is associated with reduced gut microbial diversity
    J Allergy Clin Immunol, 143 (5), 1969-1971.e11
    DOI 10.1016/j.jaci.2019.01.019, PubMed 30707969
  9. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
    Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
    Sci Rep, 9 (1), 167 (Retracted)
    DOI 10.1038/s41598-018-35367-7, PubMed 30655568
  10. Karlsen TH, Newsome PN (2019)
    The dawn of a new EASL - A new chapter in the history of the European Association for the Study of the liver
    J Hepatol, 71 (1), 5-8
    DOI 10.1016/j.jhep.2019.03.010, PubMed 31056366
  11. Kummen M, Hov JR (2019)
    The gut microbial influence on cholestatic liver disease
    Liver Int, 39 (7), 1186-1196
    DOI 10.1111/liv.14153, PubMed 31125502
  12. Liwinski T, Zenouzi R, John C, Ehlken H, Rühlemann MC, Bang C, Groth S, Lieb W, Kantowski M, Andersen N, Schachschal G, Karlsen TH, Hov JR, Rösch T, Lohse AW, Heeren J, Franke A, Schramm C (2019)
    Alterations of the bile microbiome in primary sclerosing cholangitis
    Gut, 69 (4), 665-672
    DOI 10.1136/gutjnl-2019-318416, PubMed 31243055
  13. Lunder AK, Bakstad LT, Jahnsen J, Borthne A, Hov JR, Vatn M, Negård A (2019)
    Assessment of Bowel Inflammation and Strictures by Magnetic Resonance Enterography in Long-term Crohn's Disease
    J Crohns Colitis, 13 (5), 607-614
    DOI 10.1093/ecco-jcc/jjy208, PubMed 30541145
  14. Maroni L, Pinto C, Giordano DM, Saccomanno S, Banales JM, Spallacci D, Albertini MC, Orlando F, Provinciali M, Milkiewicz M, Melum E, Labiano I, Milkiewicz P, Rychlicki C, Trozzi L, Scarpelli M, Benedetti A, Svegliati Baroni G, Marzioni M (2019)
    Aging-Related Expression of Twinfilin-1 Regulates Cholangiocyte Biological Response to Injury
    Hepatology, 70 (3), 883-898
    DOI 10.1002/hep.30466, PubMed 30561764
  15. Mayerhofer CCK, Awoyemi A, Hov JR, Trøseid M, Broch K (2019)
    Reply: Potential risk associated with direct modulation of the gut flora in patients with heart failure
    ESC Heart Fail, 6 (3), 557-558
    DOI 10.1002/ehf2.12437, PubMed 31034162
  16. Mazzawi T, Hausken T, Hov JR, Valeur J, Sangnes DA, El-Salhy M, Gilja OH, Hatlebakk JG, Lied GA (2019)
    Clinical response to fecal microbiota transplantation in patients with diarrhea-predominant irritable bowel syndrome is associated with normalization of fecal microbiota composition and short-chain fatty acid levels
    Scand J Gastroenterol, 54 (6), 690-699
    DOI 10.1080/00365521.2019.1624815, PubMed 31190584
  17. Melum E, Jiang X, Baker KD, Macedo MF, Fritsch J, Dowds CM, Wang J, Pharo A, Kaser A, Tan C, Pereira CS, Kelly SL, Duan J, Karlsen TH, Exley MA, Schütze S, Zajonc DM, Merrill AH, Schuchman EH, Zeissig S, Blumberg RS (2019)
    Control of CD1d-restricted antigen presentation and inflammation by sphingomyelin
    Nat Immunol, 20 (12), 1644-1655
    DOI 10.1038/s41590-019-0504-0, PubMed 31636468
  18. Mjelle AB, Mulabecirovic A, Havre RF, Rosendahl K, Juliusson PB, Olafsdottir E, Gilja OH, Vesterhus M (2019)
    Normal Liver Stiffness Values in Children: A Comparison of Three Different Elastography Methods
    J Pediatr Gastroenterol Nutr, 68 (5), 706-712
    DOI 10.1097/MPG.0000000000002320, PubMed 30889132
  19. Mjåland O, Nygaard A, Storm-Larsen C, Brommeland T (2019)
    Cycling-related injuries at Sørlandet Hospital, Kristiansand
    Tidsskr Nor Laegeforen, 139 (12)
    DOI 10.4045/tidsskr.19.0142, PubMed 31502796
  20. Rühlemann M, Liwinski T, Heinsen FA, Bang C, Zenouzi R, Kummen M, Thingholm L, Tempel M, Lieb W, Karlsen T, Lohse A, Hov J, Denk G, Lammert F, Krawczyk M, Schramm C, Franke A (2019)
    Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis
    Aliment Pharmacol Ther, 50 (5), 580-589
    DOI 10.1111/apt.15375, PubMed 31250469
  21. Rühlemann MC, Solovjeva MEL, Zenouzi R, Liwinski T, Kummen M, Lieb W, Hov JR, Schramm C, Franke A, Bang C (2019)
    Gut mycobiome of primary sclerosing cholangitis patients is characterised by an increase of Trichocladium griseum and Candida species
    Gut, 69 (10), 1890-1892
    DOI 10.1136/gutjnl-2019-320008, PubMed 31653787
  22. Saffioti F, Roccarina D, Vesterhus M, Hov JR, Rosenberg W, Pinzani M, Pereira SP, Boberg KM, Thorburn D (2019)
    Cholangiocarcinoma is associated with a raised enhanced liver fibrosis score independent of primary sclerosing cholangitis
    Eur J Clin Invest, 49 (5), e13088
    DOI 10.1111/eci.13088, PubMed 30762236
  23. Schneditz G, Elias JE, Pagano E, Zaeem Cader M, Saveljeva S, Long K, Mukhopadhyay S, Arasteh M, Lawley TD, Dougan G, Bassett A, Karlsen TH, Kaser A, Kaneider NC (2019)
    GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump
    Sci Signal, 12 (562)
    DOI 10.1126/scisignal.aau9048, PubMed 30600262
  24. Storm-Larsen C, Myhr KM, Farbu E, Midgard R, Nyquist K, Broch L, Berg-Hansen P, Buness A, Holm K, Ueland T, Fallang LE, Burum-Auensen E, Hov JR, Holmøy T (2019)
    Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis - a pilot trial
    Mult Scler J Exp Transl Clin, 5 (4), 2055217319888767
    DOI 10.1177/2055217319888767, PubMed 31798939
  25. Syse VL, Brekke M, Grimsrud MM, Persett PS, Heyerdahl F, Hovda KE, Vallersnes OM (2019)
    Gender differences in acute recreational drug toxicity: a case series from Oslo, Norway
    BMC Emerg Med, 19 (1), 29
    DOI 10.1186/s12873-019-0244-3, PubMed 31035940
  26. Thingholm LB, Rühlemann MC, Koch M, Fuqua B, Laucke G, Boehm R, Bang C, Franzosa EA, Hübenthal M, Rahnavard A, Frost F, Lloyd-Price J, Schirmer M, Lusis AJ, Vulpe CD, Lerch MM, Homuth G, Kacprowski T, Schmidt CO, Nöthlings U, Karlsen TH, Lieb W, Laudes M, Franke A, Huttenhower C (2019)
    Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition
    Cell Host Microbe, 26 (2), 252-264.e10
    DOI 10.1016/j.chom.2019.07.004, PubMed 31399369
  27. Trøseid M, Mayerhofer CCK, Broch K, Arora S, Svardal A, Hov JR, Andreassen AK, Gude E, Karason K, Dellgren G, Berge RK, Gullestad L, Aukrust P, Ueland T (2019)
    The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection
    J Heart Lung Transplant, 38 (10), 1097-1103
    DOI 10.1016/j.healun.2019.06.003, PubMed 31301965
  28. Tysoe OC, Justin AW, Brevini T, Chen SE, Mahbubani KT, Frank AK, Zedira H, Melum E, Saeb-Parsy K, Markaki AE, Vallier L, Sampaziotis F (2019)
    Isolation and propagation of primary human cholangiocyte organoids for the generation of bioengineered biliary tissue
    Nat Protoc, 14 (6), 1884-1925
    DOI 10.1038/s41596-019-0168-0, PubMed 31110298

Publications 2018

  1. Arnbjerg CJ, Vestad B, Hov JR, Pedersen KK, Jespersen S, Johannesen HH, Holm K, Halvorsen B, Fallentin E, Hansen AE, Lange T, Kjær A, Trøseid M, Fischer BM, Nielsen SD (2018)
    Effect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
    J Acquir Immune Defic Syndr, 78 (4), 450-457
    DOI 10.1097/QAI.0000000000001693, PubMed 29874201
  2. Berntsen NL, Fosby B, Tan C, Reims HM, Ogaard J, Jiang X, Schrumpf E, Valestrand L, Karlsen TH, Line PD, Blumberg RS, Melum E (2018)
    Natural killer T cells mediate inflammation in the bile ducts
    Mucosal Immunol, 11 (6), 1582-1590
    DOI 10.1038/s41385-018-0066-8, PubMed 30115993
  3. Broce I, Karch CM, Wen N, Fan CC, Wang Y, Tan CH, Kouri N, Ross OA, Höglinger GU, Muller U, Hardy J, International FTD-Genomics Consortium, Momeni P, Hess CP, Dillon WP, Miller ZA, Bonham LW, Rabinovici GD, Rosen HJ, Schellenberg GD, Franke A, Karlsen TH, Veldink JH, Ferrari R, Yokoyama JS et al. (2018)
    Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
    PLoS Med, 15 (1), e1002487
    DOI 10.1371/journal.pmed.1002487, PubMed 29315334
  4. Chung BK, Henriksen EKK, Jørgensen KK, Karlsen TH, Hirschfield GM, Liaskou E (2018)
    Gut and Liver B Cells of Common Clonal Origin in Primary Sclerosing Cholangitis-Inflammatory Bowel Disease
    Hepatol Commun, 2 (8), 956-967
    DOI 10.1002/hep4.1200, PubMed 30094406
  5. Colombo M, Karlsen TH (2018)
    The EASL International Liver Foundation: A growing pup with missions that are distinct yet integrated with those of its mother
    J Hepatol, 70 (3), 339-342
    DOI 10.1016/j.jhep.2018.11.017, PubMed 30577976
  6. Dhillon AK, Kummen M, Trøseid M, Åkra S, Liaskou E, Moum B, Vesterhus M, Karlsen TH, Seljeflot I, Hov JR (2018)
    Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis
    Liver Int, 39 (2), 371-381
    DOI 10.1111/liv.13979, PubMed 30269440
  7. Eaton JE, Vesterhus M, McCauley BM, Atkinson EJ, Schlicht EM, Juran BD, Gossard AA, LaRusso NF, Gores GJ, Karlsen TH, Lazaridis KN (2018)
    Primary Sclerosing Cholangitis Risk Estimate Tool (PREsTo) Predicts Outcomes of the Disease: A Derivation and Validation Study Using Machine Learning
    Hepatology, 71 (1), 214-224
    DOI 10.1002/hep.30085, PubMed 29742811
  8. Hoel H, Hove-Skovsgaard M, Hov JR, Gaardbo JC, Holm K, Kummen M, Rudi K, Nwosu F, Valeur J, Gelpi M, Seljeflot I, Ueland PM, Gerstoft J, Ullum H, Aukrust P, Nielsen SD, Trøseid M (2018)
    Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction
    Sci Rep, 8 (1), 6725
    DOI 10.1038/s41598-018-25168-3, PubMed 29712976
  9. Holmer M, Melum E, Isoniemi H, Ericzon BG, Castedal M, Nordin A, Aagaard Schultz N, Rasmussen A, Line PD, Stål P, Bennet W, Hagström H (2018)
    Nonalcoholic fatty liver disease is an increasing indication for liver transplantation in the Nordic countries
    Liver Int, 38 (11), 2082-2090
    DOI 10.1111/liv.13751, PubMed 29630771
  10. Karlsen TH, Tacke F (2018)
    «The times they are a'changin'» - Positioning the European Association for the Study of the Liver in the changing landscape of hepatology
    J Hepatol, 68 (5), 873-875
    DOI 10.1016/j.jhep.2018.02.001, PubMed 29500035
  11. Kummen M, Mayerhofer CCK, Vestad B, Broch K, Awoyemi A, Storm-Larsen C, Ueland T, Yndestad A, Hov JR, Trøseid M (2018)
    Gut Microbiota Signature in Heart Failure Defined From Profiling of 2 Independent Cohorts
    J Am Coll Cardiol, 71 (10), 1184-1186
    DOI 10.1016/j.jacc.2017.12.057, PubMed 29519360
  12. Lindström L, Jørgensen KK, Boberg KM, Castedal M, Rasmussen A, Rostved AA, Isoniemi H, Bottai M, Bergquist A (2018)
    Risk factors and prognosis for recurrent primary sclerosing cholangitis after liver transplantation: a Nordic Multicentre Study
    Scand J Gastroenterol, 53 (3), 297-304
    DOI 10.1080/00365521.2017.1421705, PubMed 29301479
  13. Mazzawi T, Lied GA, Sangnes DA, El-Salhy M, Hov JR, Gilja OH, Hatlebakk JG, Hausken T (2018)
    The kinetics of gut microbial community composition in patients with irritable bowel syndrome following fecal microbiota transplantation
    PLoS One, 13 (11), e0194904
    DOI 10.1371/journal.pone.0194904, PubMed 30427836
  14. Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, Pierik MJ, Vander Meulen-de Jong AE, Janneke van der Woude C et al. (2018)
    IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes
    Nat Commun, 9 (1), 2427
    DOI 10.1038/s41467-018-04365-8, PubMed 29930244
  15. Mulabecirovic A, Mjelle AB, Gilja OH, Vesterhus M, Havre RF (2018)
    Repeatability of shear wave elastography in liver fibrosis phantoms-Evaluation of five different systems
    PLoS One, 13 (1), e0189671
    DOI 10.1371/journal.pone.0189671, PubMed 29293527
  16. Mulabecirovic A, Mjelle AB, Gilja OH, Vesterhus M, Havre RF (2018)
    Liver elasticity in healthy individuals by two novel shear-wave elastography systems-Comparison by age, gender, BMI and number of measurements
    PLoS One, 13 (9), e0203486
    DOI 10.1371/journal.pone.0203486, PubMed 30216377
  17. Paquin-Proulx D, Greenspun BC, Pasquet L, Strunz B, Aleman S, Falconer K, Terabe M, Berzofsky JA, Sandberg JK, Melum E, Nixon DF, Björkström NK (2018)
    IL13Rα2 expression identifies tissue-resident IL-22-producing PLZF+ innate T cells in the human liver
    Eur J Immunol, 48 (8), 1329-1335
    DOI 10.1002/eji.201747334, PubMed 29677387
  18. Pihlstrøm HK, Mjøen G, Mucha S, Franke A, Jardine A, Fellström B, Dahle DO, Holdaas H, Melum E (2018)
    Genetic markers associated with long-term cardiovascular outcome in kidney transplant recipients
    Am J Transplant, 19 (5), 1444-1451
    DOI 10.1111/ajt.15191, PubMed 30457209
  19. Pollheimer MJ, Racedo S, Mikels-Vigdal A, Marshall D, Bowlus C, Lackner C, Madl T, Karlsen TH, Hov JR, Lyman SK, Adamkewicz J, Smith V, Moreau E, Zollner G, Eide TJ, Stojakovic T, Scharnagl H, Gruber HJ, Stauber RE, Trauner M, Fickert P (2018)
    Lysyl oxidase-like protein 2 (LOXL2) modulates barrier function in cholangiocytes in cholestasis
    J Hepatol, 69 (2), 368-377
    DOI 10.1016/j.jhep.2018.04.009, PubMed 29709678
  20. Schmitt C, Lenglet H, Yu A, Delaby C, Benecke A, Lefebvre T, Letteron P, Paradis V, Wahlin S, Sandberg S, Harper P, Sardh E, Sandvik AK, Hov JR, Aarsand AK, Chiche L, Bazille C, Scoazec JY, To-Figueras J, Carrascal M, Abian J, Mirmiran A, Karim Z, Deybach JC, Puy H et al. (2018)
    Recurrent attacks of acute hepatic porphyria: major role of the chronic inflammatory response in the liver
    J Intern Med, 284 (1), 78-91
    DOI 10.1111/joim.12750, PubMed 29498764
  21. Schrumpf E, Rizvi SMH (2018)
    Pustular drug rash
    Tidsskr. Nor. Laegeforen., 138 (18), 1746
  22. Thorgersen EB, Melum E, Folseraas T, Larsen SG, Line PD (2018)
    Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for pseudomyxoma peritonei in a liver-transplanted patient: a case report
    World J Surg Oncol, 16 (1), 180
    DOI 10.1186/s12957-018-1482-7, PubMed 30185175
  23. Tronstad RR, Polushina T, Brattbakk HR, Stansberg C, von Volkmann HL, Hanevik K, Ellinghaus E, Jørgensen SF, Ersland KM, Pham KD, Gilja OH, Hovdenak N, Hausken T, Vatn MH, Franke A, Knappskog PM, Le Hellard S, Karlsen TH, Fiskerstrand T (2018)
    Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea
    Scand J Gastroenterol, 53 (10-11), 1264-1273
    DOI 10.1080/00365521.2018.1521867, PubMed 30353760
  24. Åberg F, Isoniemi H, Pukkala E, Jalanko H, Rasmussen A, Storm HH, Schultz N, Bennet W, Ekvall N, Ericzon BG, Malenicka S, Tretli S, Line PD, Boberg KM, Østensen A, Karlsen TH, Nordin A (2018)
    Cancer After Liver Transplantation in Children and Young Adults: A Population-Based Study From 4 Nordic Countries
    Liver Transpl, 24 (9), 1252-1259
    DOI 10.1002/lt.25305, PubMed 30120902

Publications 2017

  1. Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, Böttcher K, Folseraas T, Weismüller TJ, Mason AL, Wang W, Alexander G, Alvaro D, Bergquist A, Björkström NK, Beuers U, Björnsson E, Boberg KM, Bowlus CL, Bragazzi MC, Carbone M, Chazouillères O, Cheung A, Dalekos G, Eaton J et al. (2017)
    Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis
    Gut, 67 (8), 1517-1524
    DOI 10.1136/gutjnl-2016-313598, PubMed 28779025
  2. Bende F, Mulabecirovic A, Sporea I, Popescu A, Sirli R, Gilja OH, Vesterhus M, Havre RF (2017)
    Assessing Liver Stiffness by 2-D Shear Wave Elastography in a Healthy Cohort
    Ultrasound Med Biol, 44 (2), 332-341
    DOI 10.1016/j.ultrasmedbio.2017.10.013, PubMed 29249457
  3. Berntsen NL, Fosby B, Valestrand L, Tan C, Reims HM, Schrumpf E, Karlsen TH, Line PD, Melum E (2017)
    Establishment of a surgical bile duct injection technique giving direct access to the bile ducts for studies of the murine biliary tree
    Am J Physiol Gastrointest Liver Physiol, 314 (3), G349-G359
    DOI 10.1152/ajpgi.00124.2017, PubMed 29212771
  4. Carpino G, Cardinale V, Folseraas T, Overi D, Floreani A, Franchitto A, Onori P, Cazzagon N, Berloco PB, Karlsen TH, Alvaro D, Gaudio E (2017)
    Hepatic Stem/Progenitor Cell Activation Differs between Primary Sclerosing and Primary Biliary Cholangitis
    Am J Pathol, 188 (3), 627-639
    DOI 10.1016/j.ajpath.2017.11.010, PubMed 29248458
  5. Chung BK, Hirschfield GM (2017)
    Immunogenetics in primary sclerosing cholangitis
    Curr Opin Gastroenterol, 33 (2), 93-98
    DOI 10.1097/MOG.0000000000000336, PubMed 28146446
  6. Chung BK, Karlsen TH (2017)
    Genetic Discoveries Highlight Environmental Factors as Key Drivers of Liver Disease
    Dig Dis, 35 (4), 323-333
    DOI 10.1159/000456583, PubMed 28468012
  7. Chung BK, Karlsen TH, Folseraas T (2017)
    Cholangiocytes in the pathogenesis of primary sclerosing cholangitis and development of cholangiocarcinoma
    Biochim Biophys Acta Mol Basis Dis, 1864 (4 Pt B), 1390-1400
    DOI 10.1016/j.bbadis.2017.08.020, PubMed 28844951
  8. Claussen JC, Skiecevičienė J, Wang J, Rausch P, Karlsen TH, Lieb W, Baines JF, Franke A, Hütt MT (2017)
    Boolean analysis reveals systematic interactions among low-abundance species in the human gut microbiome
    PLoS Comput Biol, 13 (6), e1005361
    DOI 10.1371/journal.pcbi.1005361, PubMed 28640804
  9. de Muinck EJ, Trosvik P, Gilfillan GD, Hov JR, Sundaram AYM (2017)
    A novel ultra high-throughput 16S rRNA gene amplicon sequencing library preparation method for the Illumina HiSeq platform
    Microbiome, 5 (1), 68
    DOI 10.1186/s40168-017-0279-1, PubMed 28683838
  10. de Vries EMG, Färkkilä M, Milkiewicz P, Hov JR, Eksteen B, Thorburn D, Chazouillères O, Pares A, Nygård S, Gilja OH, Wunsch E, Invernizzi P, Carbone M, Bernuzzi F, Boberg KM, Røsjø H, Rosenberg W, Beuers UH, Ponsioen CY, Karlsen TH, Vesterhus M (2017)
    Enhanced liver fibrosis test predicts transplant-free survival in primary sclerosing cholangitis, a multi-centre study
    Liver Int, 37 (10), 1554-1561
    DOI 10.1111/liv.13402, PubMed 28267887
  11. Haissman JM, Haugaard AK, Ostrowski SR, Berge RK, Hov JR, Trøseid M, Nielsen SD (2017)
    Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection
    BMC Infect Dis, 17 (1), 445
    DOI 10.1186/s12879-017-2547-x, PubMed 28645263
  12. Henriksen EKK, Viken MK, Wittig M, Holm K, Folseraas T, Mucha S, Melum E, Hov JR, Lazaridis KN, Juran BD, Chazouillères O, Färkkilä M, Gotthardt DN, Invernizzi P, Carbone M, Hirschfield GM, Rushbrook SM, Goode E, UK-PSC Consortium, Ponsioen CY, Weersma RK, Eksteen B, Yimam KK, Gordon SC, Goldberg D et al. (2017)
    HLA haplotypes in primary sclerosing cholangitis patients of admixed and non-European ancestry
    HLA, 90 (4), 228-233
    DOI 10.1111/tan.13076, PubMed 28695657
  13. Hov JR, Karlsen TH (2017)
    The Microbiome in Primary Sclerosing Cholangitis: Current Evidence and Potential Concepts
    Semin Liver Dis, 37 (4), 314-331
    DOI 10.1055/s-0037-1608801, PubMed 29272894
  14. Hov JR, Kummen M (2017)
    Intestinal microbiota in primary sclerosing cholangitis
    Curr Opin Gastroenterol, 33 (2), 85-92
    DOI 10.1097/MOG.0000000000000334, PubMed 28030369
  15. Jahnsen FL, Bækkevold ES, Hov JR, Landsverk OJ (2017)
    Do Long-Lived Plasma Cells Maintain a Healthy Microbiota in the Gut?
    Trends Immunol, 39 (3), 196-208
    DOI 10.1016/, PubMed 29162322
  16. Jahnsen J, Kaasen Jørgensen K (2017)
    Experience with Biosimilar Infliximab (Remsima®) in Norway
    Dig Dis, 35 (1-2), 83-90
    DOI 10.1159/000449088, PubMed 28147374
  17. Jiang X, Björkström NK, Melum E (2017)
    Intact CD100-CD72 Interaction Necessary for TCR-Induced T Cell Proliferation
    Front Immunol, 8, 765
    DOI 10.3389/fimmu.2017.00765, PubMed 28713384
  18. Jiang X, Karlsen TH (2017)
    Genetics of primary sclerosing cholangitis and pathophysiological implications
    Nat Rev Gastroenterol Hepatol, 14 (5), 279-295
    DOI 10.1038/nrgastro.2016.154, PubMed 28293027
  19. Karlsen TH, Folseraas T, Thorburn D, Vesterhus M (2017)
    Primary sclerosing cholangitis - a comprehensive review
    J Hepatol, 67 (6), 1298-1323
    DOI 10.1016/j.jhep.2017.07.022, PubMed 28802875
  20. Koch M, Freitag-Wolf S, Schlesinger S, Borggrefe J, Hov JR, Jensen MK, Pick J, Markus MRP, Höpfner T, Jacobs G, Siegert S, Artati A, Kastenmüller G, Römisch-Margl W, Adamski J, Illig T, Nothnagel M, Karlsen TH, Schreiber S, Franke A, Krawczak M, Nöthlings U, Lieb W (2017)
    Serum metabolomic profiling highlights pathways associated with liver fat content in a general population sample
    Eur J Clin Nutr, 71 (8), 995-1001
    DOI 10.1038/ejcn.2017.43, PubMed 28378853
  21. Landskron J, Kraggerud SM, Wik E, Dørum A, Bjørnslett M, Melum E, Helland Ø, Bjørge L, Lothe RA, Salvesen HB, Taskén K (2017)
    C77G in PTPRC (CD45) is no risk allele for ovarian cancer, but associated with less aggressive disease
    PLoS One, 12 (7), e0182030
    DOI 10.1371/journal.pone.0182030, PubMed 28759630
  22. Lunder AK, Jahnsen J, Bakstad LT, Borthne A, Hov JR, Vatn M, Negård A, IBSEN Study Group (2017)
    Bowel Damage in Patients With Long-term Crohn's Disease, Assessed by Magnetic Resonance Enterography and the Lémann Index
    Clin Gastroenterol Hepatol, 16 (1), 75-82.e5
    DOI 10.1016/j.cgh.2017.06.053, PubMed 28694130
  23. Maroni L, Hohenester SD, van de Graaf SFJ, Tolenaars D, van Lienden K, Verheij J, Marzioni M, Karlsen TH, Oude Elferink RPJ, Beuers U (2017)
    Knockout of the primary sclerosing cholangitis-risk gene Fut2 causes liver disease in mice
    Hepatology, 66 (2), 542-554
    DOI 10.1002/hep.29029, PubMed 28056490
  24. Mayerhofer CCK, Ueland T, Broch K, Vincent RP, Cross GF, Dahl CP, Aukrust P, Gullestad L, Hov JR, Trøseid M (2017)
    Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure
    J Card Fail, 23 (9), 666-671
    DOI 10.1016/j.cardfail.2017.06.007, PubMed 28688889
  25. Meijerink H, White RA, Løvlie A, de Blasio BF, Dalgard O, Amundsen EJ, Melum E, Kløvstad H (2017)
    Modelling the burden of hepatitis C infection among people who inject drugs in Norway, 1973-2030
    BMC Infect Dis, 17 (1), 541
    DOI 10.1186/s12879-017-2631-2, PubMed 28774261
  26. Nordin A, Åberg F, Pukkala E, Pedersen CR, Storm HH, Rasmussen A, Bennet W, Olausson M, Wilczek H, Ericzon BG, Tretli S, Line PD, Karlsen TH, Boberg KM, Isoniemi H (2017)
    Decreasing incidence of cancer after liver transplantation-A Nordic population-based study over 3 decades
    Am J Transplant, 18 (4), 952-963
    DOI 10.1111/ajt.14507, PubMed 28925583
  27. O'Hara SP, Karlsen TH, LaRusso NF (2017)
    Cholangiocytes and the environment in primary sclerosing cholangitis: where is the link?
    Gut, 66 (11), 1873-1877
    DOI 10.1136/gutjnl-2017-314249, PubMed 28733279
  28. Rosati E, Dowds CM, Liaskou E, Henriksen EKK, Karlsen TH, Franke A (2017)
    Overview of methodologies for T-cell receptor repertoire analysis
    BMC Biotechnol, 17 (1), 61
    DOI 10.1186/s12896-017-0379-9, PubMed 28693542
  29. Rühlemann MC, Degenhardt F, Thingholm LB, Wang J, Skiecevičienė J, Rausch P, Hov JR, Lieb W, Karlsen TH, Laudes M, Baines JF, Heinsen FA, Franke A (2017)
    Application of the distance-based F test in an mGWAS investigating β diversity of intestinal microbiota identifies variants in SLC9A8 (NHE8) and 3 other loci
    Gut Microbes, 9 (1), 68-75
    DOI 10.1080/19490976.2017.1356979, PubMed 28816579
  30. Sampaziotis F, Justin AW, Tysoe OC, Sawiak S, Godfrey EM, Upponi SS, Gieseck RL, de Brito MC, Berntsen NL, Gómez-Vázquez MJ, Ortmann D, Yiangou L, Ross A, Bargehr J, Bertero A, Zonneveld MCF, Pedersen MT, Pawlowski M, Valestrand L, Madrigal P, Georgakopoulos N, Pirmadjid N, Skeldon GM, Casey J, Shu W et al. (2017)
    Reconstruction of the mouse extrahepatic biliary tree using primary human extrahepatic cholangiocyte organoids
    Nat Med, 23 (8), 954-963
    DOI 10.1038/nm.4360, PubMed 28671689
  31. Schrumpf E, Jiang X, Zeissig S, Pollheimer MJ, Anmarkrud JA, Tan C, Exley MA, Karlsen TH, Blumberg RS, Melum E (2017)
    The role of natural killer T cells in a mouse model with spontaneous bile duct inflammation
    Physiol Rep, 5 (4)
    DOI 10.14814/phy2.13117, PubMed 28219981
  32. Trivedi PJ, Tickle J, Vesterhus MN, Eddowes PJ, Bruns T, Vainio J, Parker R, Smith D, Liaskou E, Thorbjørnsen LW, Hirschfield GM, Auvinen K, Hubscher SG, Salmi M, Adams DH, Weston CJ (2017)
    Vascular adhesion protein-1 is elevated in primary sclerosing cholangitis, is predictive of clinical outcome and facilitates recruitment of gut-tropic lymphocytes to liver in a substrate-dependent manner
    Gut, 67 (6), 1135-1145
    DOI 10.1136/gutjnl-2016-312354, PubMed 28428344
  33. Tronstad RR, Kummen M, Holm K, von Volkmann HL, Anmarkrud JA, Høivik ML, Moum B, Gilja OH, Hausken T, Baines J, Karlsen TH, Fiskerstrand T, Hov JR (2017)
    Guanylate Cyclase C Activation Shapes the Intestinal Microbiota in Patients with Familial Diarrhea and Increased Susceptibility for Crohn's Disease
    Inflamm Bowel Dis, 23 (10), 1752-1761
    DOI 10.1097/MIB.0000000000001264, PubMed 28902124
  34. Vesterhus M, Holm A, Hov JR, Nygård S, Schrumpf E, Melum E, Thorbjørnsen LW, Paulsen V, Lundin K, Dale I, Gilja OH, Zweers SJLB, Vatn M, Schaap FG, Jansen PLM, Ueland T, Røsjø H, Moum B, Ponsioen CY, Boberg KM, Färkkilä M, Karlsen TH, Lund-Johansen F (2017)
    Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis
    J Hepatol, 66 (6), 1214-1222
    DOI 10.1016/j.jhep.2017.01.019, PubMed 28161472
  35. Volkmann ER, Hoffmann-Vold AM, Chang YL, Jacobs JP, Tillisch K, Mayer EA, Clements PJ, Hov JR, Kummen M, Midtvedt Ø, Lagishetty V, Chang L, Labus JS, Molberg Ø, Braun J (2017)
    Systemic sclerosis is associated with specific alterations in gastrointestinal microbiota in two independent cohorts
    BMJ Open Gastroenterol, 4 (1), e000134
    DOI 10.1136/bmjgast-2017-000134, PubMed 28761687
  36. Weismüller TJ, Trivedi PJ, Bergquist A, Imam M, Lenzen H, Ponsioen CY, Holm K, Gotthardt D, Färkkilä MA, Marschall HU, Thorburn D, Weersma RK, Fevery J, Mueller T, Chazouillères O, Schulze K, Lazaridis KN, Almer S, Pereira SP, Levy C, Mason A, Naess S, Bowlus CL, Floreani A, Halilbasic E et al. (2017)
    Patient Age, Sex, and Inflammatory Bowel Disease Phenotype Associate With Course of Primary Sclerosing Cholangitis
    Gastroenterology, 152 (8), 1975-1984.e8
    DOI 10.1053/j.gastro.2017.02.038, PubMed 28274849
  37. Aabakken L, Karlsen TH, Albert J, Arvanitakis M, Chazouilleres O, Dumonceau JM, Färkkilä M, Fickert P, Hirschfield GM, Laghi A, Marzioni M, Fernandez M, Pereira SP, Pohl J, Poley JW, Ponsioen CY, Schramm C, Swahn F, Tringali A, Hassan C (2017)
    Role of endoscopy in primary sclerosing cholangitis: European Society of Gastrointestinal Endoscopy (ESGE) and European Association for the Study of the Liver (EASL) Clinical Guideline
    Endoscopy, 49 (6), 588-608
    DOI 10.1055/s-0043-107029, PubMed 28420030

Publications 2016

  1. Banales JM, Cardinale V, Carpino G, Marzioni M, Andersen JB, Invernizzi P, Lind GE, Folseraas T, Forbes SJ, Fouassier L, Geier A, Calvisi DF, Mertens JC, Trauner M, Benedetti A, Maroni L, Vaquero J, Macias RI, Raggi C, Perugorria MJ, Gaudio E, Boberg KM, Marin JJ, Alvaro D (2016)
    Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
    Nat Rev Gastroenterol Hepatol, 13 (5), 261-80
    DOI 10.1038/nrgastro.2016.51, PubMed 27095655
  2. Bernuzzi F, Marabita F, Lleo A, Carbone M, Mirolo M, Marzioni M, Alpini G, Alvaro D, Boberg KM, Locati M, Torzilli G, Rimassa L, Piscaglia F, He XS, Bowlus CL, Yang GX, Gershwin ME, Invernizzi P (2016)
    Serum microRNAs as novel biomarkers for primary sclerosing cholangitis and cholangiocarcinoma
    Clin Exp Immunol, 185 (1), 61-71
    DOI 10.1111/cei.12776, PubMed 26864161
  3. Chung BK, Guevel BT, Reynolds GM, Gupta Udatha DB, Henriksen EK, Stamataki Z, Hirschfield GM, Karlsen TH, Liaskou E (2016)
    Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis
    J Autoimmun, 77, 45-54
    DOI 10.1016/j.jaut.2016.10.003, PubMed 27784538
  4. Ellinghaus D, Jostins L, Spain SL, Cortes A, Bethune J, Han B, Park YR, Raychaudhuri S, Pouget JG, Hübenthal M, Folseraas T, Wang Y, Esko T, Metspalu A, Westra HJ, Franke L, Pers TH, Weersma RK, Collij V, D'Amato M, Halfvarson J, Jensen AB, Lieb W, Degenhardt F, Forstner AJ et al. (2016)
    Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
    Nat Genet, 48 (5), 510-8
    DOI 10.1038/ng.3528, PubMed 26974007
  5. Gabrielsen IS, Amundsen SS, Helgeland H, Flåm ST, Hatinoor N, Holm K, Viken MK, Lie BA (2016)
    Genetic risk variants for autoimmune diseases that influence gene expression in thymus
    Hum Mol Genet, 25 (14), 3117-3124
    DOI 10.1093/hmg/ddw152, PubMed 27199374
  6. Gabrielsen IS, Viken MK, Amundsen SS, Helgeland H, Holm K, Flåm ST, Lie BA (2016)
    Autoimmune risk variants in ERAP2 are associated with gene-expression levels in thymus
    Genes Immun, 17 (7), 406-411
    DOI 10.1038/gene.2016.39, PubMed 27829666
  7. Henriksen EK, Jørgensen KK, Kaveh F, Holm K, Hamm D, Olweus J, Melum E, Chung BK, Eide TJ, Lundin KE, Boberg KM, Karlsen TH, Hirschfield GM, Liaskou E (2016)
    Gut and liver T-cells of common clonal origin in primary sclerosing cholangitis-inflammatory bowel disease
    J Hepatol, 66 (1), 116-122
    DOI 10.1016/j.jhep.2016.09.002, PubMed 27647428
  8. Hov JR, Boberg KM, Taraldsrud E, Vesterhus M, Boyadzhieva M, Solberg IC, Schrumpf E, Vatn MH, Lie BA, Molberg Ø, Karlsen TH (2016)
    Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis
    Liver Int, 37 (3), 458-465
    DOI 10.1111/liv.13238, PubMed 27558072
  9. Jendrek ST, Gotthardt D, Nitzsche T, Widmann L, Korf T, Michaels MA, Weiss KH, Liaskou E, Vesterhus M, Karlsen TH, Mindorf S, Schemmer P, Bär F, Teegen B, Schröder T, Ehlers M, Hammers CM, Komorowski L, Lehnert H, Fellermann K, Derer S, Hov JR, Sina C (2016)
    Anti-GP2 IgA autoantibodies are associated with poor survival and cholangiocarcinoma in primary sclerosing cholangitis
    Gut, 66 (1), 137-144
    DOI 10.1136/gutjnl-2016-311739, PubMed 27406039
  10. Ji SG, Juran BD, Mucha S, Folseraas T, Jostins L, Melum E, Kumasaka N, Atkinson EJ, Schlicht EM, Liu JZ, Shah T, Gutierrez-Achury J, Boberg KM, Bergquist A, Vermeire S, Eksteen B, Durie PR, Farkkila M, Müller T, Schramm C, Sterneck M, Weismüller TJ, Gotthardt DN, Ellinghaus D, Braun F et al. (2016)
    Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease
    Nat Genet, 49 (2), 269-273
    DOI 10.1038/ng.3745, PubMed 27992413
  11. Jørgensen SF, Macpherson ME, Bjøro K, Karlsen TH, Reims HM, Grzyb K, Fosby B, Fevang B, Aukrust P, Nordøy I (2016)
    Liver transplantation in patients with primary antibody deficiency
    J Allergy Clin Immunol, 139 (5), 1708-1710.e2
    DOI 10.1016/j.jaci.2016.10.025, PubMed 27931972
  12. Jørgensen SF, Reims HM, Frydenlund D, Holm K, Paulsen V, Michelsen AE, Jørgensen KK, Osnes LT, Bratlie J, Eide TJ, Dahl CP, Holter E, Tronstad RR, Hanevik K, Brattbakk HR, Kaveh F, Fiskerstrand T, Kran AB, Ueland T, Karlsen TH, Aukrust P, Lundin KE, Fevang B (2016)
    A Cross-Sectional Study of the Prevalence of Gastrointestinal Symptoms and Pathology in Patients With Common Variable Immunodeficiency
    Am J Gastroenterol, 111 (10), 1467-1475
    DOI 10.1038/ajg.2016.329, PubMed 27527747
  13. Jørgensen SF, Trøseid M, Kummen M, Anmarkrud JA, Michelsen AE, Osnes LT, Holm K, Høivik ML, Rashidi A, Dahl CP, Vesterhus M, Halvorsen B, Mollnes TE, Berge RK, Moum B, Lundin KE, Fevang B, Ueland T, Karlsen TH, Aukrust P, Hov JR (2016)
    Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
    Mucosal Immunol, 9 (6), 1455-1465
    DOI 10.1038/mi.2016.18, PubMed 26982597
  14. Karlsen TH (2016)
    Primary sclerosing cholangitis: 50 years of a gut-liver relationship and still no love?
    Gut, 65 (10), 1579-81
    DOI 10.1136/gutjnl-2016-312137, PubMed 27402486
  15. Knudsen A, Christensen TE, Thorsteinsson K, Ghotbi AA, Hasbak P, Lebech AM, Nielsen SD, Hov JR, Berge R, Ripa RS, Kjær A, Trøseid M (2016)
    Microbiota-Dependent Marker TMAO is Not Associated With Decreased Myocardial Perfusion in Well-Treated HIV-Infected Patients as Assessed by 82Rubidium PET/CT
    J Acquir Immune Defic Syndr, 72 (4), e83-5
    DOI 10.1097/QAI.0000000000001044, PubMed 27152465
  16. Kummen M, Hov JR (2016)
    Response to 'Faecal microbiota profiles as diagnostic biomarkers in primary sclerosing cholangitis' by Rühlemann et al
    Gut, 66 (4), 755-756
    DOI 10.1136/gutjnl-2016-312347, PubMed 27340191
  17. Kummen M, Vesterhus M, Trøseid M, Moum B, Svardal A, Boberg KM, Aukrust P, Karlsen TH, Berge RK, Hov JR (2016)
    Elevated trimethylamine-N-oxide (TMAO) is associated with poor prognosis in primary sclerosing cholangitis patients with normal liver function
    United European Gastroenterol J, 5 (4), 532-541
    DOI 10.1177/2050640616663453, PubMed 28588885
  18. Lunder AK, Hov JR, Borthne A, Gleditsch J, Johannesen G, Tveit K, Viktil E, Henriksen M, Hovde Ø, Huppertz-Hauss G, Høie O, Høivik ML, Monstad I, Solberg IC, Jahnsen J, Karlsen TH, Moum B, Vatn M, Negård A (2016)
    Prevalence of Sclerosing Cholangitis Detected by Magnetic Resonance Cholangiography in Patients With Long-term Inflammatory Bowel Disease
    Gastroenterology, 151 (4), 660-669.e4
    DOI 10.1053/j.gastro.2016.06.021, PubMed 27342213
  19. Maroni L, Agostinelli L, Saccomanno S, Pinto C, Giordano DM, Rychlicki C, De Minicis S, Trozzi L, Banales JM, Melum E, Karlsen TH, Benedetti A, Baroni GS, Marzioni M (2016)
    Nlrp3 Activation Induces Il-18 Synthesis and Affects the Epithelial Barrier Function in Reactive Cholangiocytes
    Am J Pathol, 187 (2), 366-376
    DOI 10.1016/j.ajpath.2016.10.010, PubMed 27912077
  20. Mjelle AB, Mulabecirovic A, Hausken T, Havre RF, Gilja OH, Vesterhus M (2016)
    Ultrasound and Point Shear Wave Elastography in Livers of Patients with Primary Sclerosing Cholangitis
    Ultrasound Med Biol, 42 (9), 2146-55
    DOI 10.1016/j.ultrasmedbio.2016.04.016, PubMed 27262519
  21. Mulabecirovic A, Vesterhus M, Gilja OH, Havre RF (2016)
    In Vitro Comparison of Five Different Elastography Systems for Clinical Applications, Using Strain and Shear Wave Technology
    Ultrasound Med Biol, 42 (11), 2572-2588
    DOI 10.1016/j.ultrasmedbio.2016.07.002, PubMed 27570209
  22. Pihlstrøm HK, Mjøen G, Mucha S, Haraldsen G, Franke A, Jardine A, Fellström B, Holdaas H, Melum E (2016)
    Single Nucleotide Polymorphisms and Long-Term Clinical Outcome in Renal Transplant Patients: A Validation Study
    Am J Transplant, 17 (2), 528-533
    DOI 10.1111/ajt.13995, PubMed 27483393
  23. Schrumpf E, Kummen M, Valestrand L, Greiner TU, Holm K, Arulampalam V, Reims HM, Baines J, Bäckhed F, Karlsen TH, Blumberg RS, Hov JR, Melum E (2016)
    The gut microbiota contributes to a mouse model of spontaneous bile duct inflammation
    J Hepatol, 66 (2), 382-389
    DOI 10.1016/j.jhep.2016.09.020, PubMed 27720803
  24. Skagen K, Trøseid M, Ueland T, Holm S, Abbas A, Gregersen I, Kummen M, Bjerkeli V, Reier-Nilsen F, Russell D, Svardal A, Karlsen TH, Aukrust P, Berge RK, Hov JE, Halvorsen B, Skjelland M (2016)
    The Carnitine-butyrobetaine-trimethylamine-N-oxide pathway and its association with cardiovascular mortality in patients with carotid atherosclerosis
    Atherosclerosis, 247, 64-9
    DOI 10.1016/j.atherosclerosis.2016.01.033, PubMed 26868510
  25. Saadati HR, Wittig M, Helbig I, Häsler R, Anderson CA, Mathew CG, Kupcinskas L, Parkes M, Karlsen TH, Rosenstiel P, Schreiber S, Franke A (2016)
    Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci
    BMC Med Genet, 17, 26
    DOI 10.1186/s12881-016-0289-z, PubMed 27037036
  26. Trøseid M, Hov JR, Nestvold TK, Thoresen H, Berge RK, Svardal A, Lappegård KT (2016)
    Major Increase in Microbiota-Dependent Proatherogenic Metabolite TMAO One Year After Bariatric Surgery
    Metab Syndr Relat Disord, 14 (4), 197-201
    DOI 10.1089/met.2015.0120, PubMed 27081744
  27. Vesterhus M, Melum E (2016)
    Prognostic biomarkers and surrogate end points in PSC
    Liver Int, 36 (12), 1748-1751
    DOI 10.1111/liv.13216, PubMed 27864874
  28. Yokoyama JS, Wang Y, Schork AJ, Thompson WK, Karch CM, Cruchaga C, McEvoy LK, Witoelar A, Chen CH, Holland D, Brewer JB, Franke A, Dillon WP, Wilson DM, Mukherjee P, Hess CP, Miller Z, Bonham LW, Shen J, Rabinovici GD, Rosen HJ, Miller BL, Hyman BT, Schellenberg GD, Karlsen TH et al. (2016)
    Association Between Genetic Traits for Immune-Mediated Diseases and Alzheimer Disease
    JAMA Neurol, 73 (6), 691-7
    DOI 10.1001/jamaneurol.2016.0150, PubMed 27088644
  29. Zweers SJ, Shiryaev A, Komuta M, Vesterhus M, Hov JR, Perugorria MJ, de Waart DR, Chang JC, Tol S, Te Velde AA, de Jonge WJ, Banales JM, Roskams T, Beuers U, Karlsen TH, Jansen PL, Schaap FG (2016)
    Elevated interleukin-8 in bile of patients with primary sclerosing cholangitis
    Liver Int, 36 (9), 1370-7
    DOI 10.1111/liv.13092, PubMed 26866350

Publications 2015

  1. Andersen IM, Fosby B, Boberg KM, Clausen OP, Jebsen P, Melum E, Line PD, Foss A, Schrumpf E, Karlsen TH (2015)
    Indications and Outcomes in Liver Transplantation in Patients With Primary Sclerosing Cholangitis in Norway
    Transplant Direct, 1 (9), e39
    DOI 10.1097/TXD.0000000000000548, PubMed 27500239
  2. Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
    Abundant genetic overlap between blood lipids and immune-mediated diseases indicates shared molecular genetic mechanisms
    PLoS One, 10 (4), e0123057
    DOI 10.1371/journal.pone.0123057, PubMed 25853426
  3. Andreassen OA, Desikan RS, Wang Y, Thompson WK, Schork AJ, Zuber V, Doncheva NT, Ellinghaus E, Albrecht M, Mattingsdal M, Franke A, Lie BA, Mills IG, Aukrust P, McEvoy LK, Djurovic S, Karlsen TH, Dale AM (2015)
    Correction: Abundant Genetic Overlap between Blood Lipids and Immune-Mediated Diseases Indicates Shared Molecular Genetic Mechanisms
    PLoS One, 10 (5), e0128048
    DOI 10.1371/journal.pone.0128048, PubMed 25978331
  4. Andresen K, Boberg KM, Vedeld HM, Honne H, Jebsen P, Hektoen M, Wadsworth CA, Clausen OP, Lundin KE, Paulsen V, Foss A, Mathisen Ø, Aabakken L, Schrumpf E, Lothe RA, Lind GE (2015)
    Four DNA methylation biomarkers in biliary brush samples accurately identify the presence of cholangiocarcinoma
    Hepatology, 61 (5), 1651-9
    DOI 10.1002/hep.27707, PubMed 25644509
  5. Berntsen NL, Klingenberg O, Juran BD, Benito de Valle M, Lindkvist B, Lazaridis KN, Boberg KM, Karlsen TH, Hov JR (2015)
    Association Between HLA Haplotypes and Increased Serum Levels of IgG4 in Patients With Primary Sclerosing Cholangitis
    Gastroenterology, 148 (5), 924-927.e2
    DOI 10.1053/j.gastro.2015.01.041, PubMed 25655558
  6. Carpino G, Cardinale V, Renzi A, Hov JR, Berloco PB, Rossi M, Karlsen TH, Alvaro D, Gaudio E (2015)
    Activation of biliary tree stem cells within peribiliary glands in primary sclerosing cholangitis
    J Hepatol, 63 (5), 1220-8
    DOI 10.1016/j.jhep.2015.06.018, PubMed 26119688
  7. Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, Brant SR, Cho JH, Daly MJ, Dubinsky M, Duerr RH, Ferguson LR, Franke A, Gearry RB, Goyette P, Hakonarson H, Halfvarson J, Hov JR, Huang H, Kennedy NA, Kupcinskas L et al. (2015)
    Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study
    Lancet, 387 (10014), 156-67
    DOI 10.1016/S0140-6736(15)00465-1, PubMed 26490195
  8. D'Agnolo HM, Kievit W, Andrade RJ, Karlsen TH, Wedemeyer H, Drenth JP (2015)
    Creating an effective clinical registry for rare diseases
    United European Gastroenterol J, 4 (3), 333-8
    DOI 10.1177/2050640615618042, PubMed 27403298
  9. Folseraas T, Boberg KM (2015)
    Cancer Risk and Surveillance in Primary Sclerosing Cholangitis
    Clin Liver Dis, 20 (1), 79-98
    DOI 10.1016/j.cld.2015.08.014, PubMed 26593292
  10. Folseraas T, Liaskou E, Anderson CA, Karlsen TH (2015)
    Genetics in PSC: what do the "risk genes" teach us?
    Clin Rev Allergy Immunol, 48 (2-3), 154-64
    DOI 10.1007/s12016-014-8417-z, PubMed 24736995
  11. Fosby B, Melum E, Bjøro K, Bennet W, Rasmussen A, Andersen IM, Castedal M, Olausson M, Wibeck C, Gotlieb M, Gjertsen H, Toivonen L, Foss S, Makisalo H, Nordin A, Sanengen T, Bergquist A, Larsson ME, Soderdahl G, Nowak G, Boberg KM, Isoniemi H, Keiding S, Foss A, Line PD et al. (2015)
    Liver transplantation in the Nordic countries - An intention to treat and post-transplant analysis from The Nordic Liver Transplant Registry 1982-2013
    Scand J Gastroenterol, 50 (6), 797-808
    DOI 10.3109/00365521.2015.1036359, PubMed 25959101
  12. Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, Oksenberg JR, Thomsen I, Leslie S, International Inflammatory Bowel Disease Genetics Consortium, Australia and New Zealand IBDGC, Belgium IBD Genetics Consortium, Italian Group for IBD Genetic Consortium, NIDDK Inflammatory Bowel Disease Genetics Consortium, United Kingdom IBDGC, Wellcome Trust Case Control Consortium, Quebec IBD Genetics Consortium, Daly MJ, Van Steen K, Duerr RH, Barrett JC et al. (2015)
    High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis
    Nat Genet, 47 (2), 172-9
    DOI 10.1038/ng.3176, PubMed 25559196
  13. Hov JE, Trøseid M (2015)
    Personalised medicine targeting the gut microbiota?
    Tidsskr Nor Laegeforen, 135 (7), 624
    DOI 10.4045/tidsskr.14.1431, PubMed 25899345
  14. Hov JER, Troseid M (2015)
    Personalized intestinal flora medicine?
    Tidsskr. Nor. Laegeforen., 135 (7), 624
  15. Hov JR, Zhong H, Qin B, Anmarkrud JA, Holm K, Franke A, Lie BA, Karlsen TH (2015)
    The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study
    PLoS One, 10 (7), e0133804
    DOI 10.1371/journal.pone.0133804, PubMed 26207384
  16. Karlsen TH, Chung BK (2015)
    Genetic Risk and the Development of Autoimmune Liver Disease
    Dig Dis, 33 Suppl 2, 13-24
    DOI 10.1159/000440706, PubMed 26641277
  17. Karlsen TH, Lammert F, Thompson RJ (2015)
    Genetics of liver disease: From pathophysiology to clinical practice
    J Hepatol, 62 (1 Suppl), S6-S14
    DOI 10.1016/j.jhep.2015.02.025, PubMed 25920091
  18. Kevans D, Tyler AD, Holm K, Jørgensen KK, Vatn MH, Karlsen TH, Kaplan GG, Eksteen B, Gevers D, Hov JR, Silverberg MS (2015)
    Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis
    J Crohns Colitis, 10 (3), 330-7
    DOI 10.1093/ecco-jcc/jjv204, PubMed 26526357
  19. Li J, Jørgensen SF, Maggadottir SM, Bakay M, Warnatz K, Glessner J, Pandey R, Salzer U, Schmidt RE, Perez E, Resnick E, Goldacker S, Buchta M, Witte T, Padyukov L, Videm V, Folseraas T, Atschekzei F, Elder JT, Nair RP, Winkelmann J, Gieger C, Nöthen MM, Büning C, Brand S et al. (2015)
    Association of CLEC16A with human common variable immunodeficiency disorder and role in murine B cells
    Nat Commun, 6, 6804
    DOI 10.1038/ncomms7804, PubMed 25891430
  20. Liaskou E, Klemsdal Henriksen EK, Holm K, Kaveh F, Hamm D, Fear J, Viken MK, Hov JR, Melum E, Robins H, Olweus J, Karlsen TH, Hirschfield GM (2015)
    High-throughput T-cell receptor sequencing across chronic liver diseases reveals distinct disease-associated repertoires
    Hepatology, 63 (5), 1608-19
    DOI 10.1002/hep.28116, PubMed 26257205
  21. Olin P, Hausken J, Foss A, Karlsen TH, Melum E, Haugaa H (2015)
    Continuous molecular adsorbent recirculating system treatment in 69 patients listed for liver transplantation
    Scand J Gastroenterol, 50 (9), 1127-34
    DOI 10.3109/00365521.2015.1027262, PubMed 25865318
  22. Ponsioen CY, Chapman RW, Chazouillères O, Hirschfield GM, Karlsen TH, Lohse AW, Pinzani M, Schrumpf E, Trauner M, Gores GJ (2015)
    Surrogate endpoints for clinical trials in primary sclerosing cholangitis: Review and results from an International PSC Study Group consensus process
    Hepatology, 63 (4), 1357-67
    DOI 10.1002/hep.28256, PubMed 26418478
  23. Sampaziotis F, de Brito MC, Madrigal P, Bertero A, Saeb-Parsy K, Soares FAC, Schrumpf E, Melum E, Karlsen TH, Bradley JA, Gelson WT, Davies S, Baker A, Kaser A, Alexander GJ, Hannan NRF, Vallier L (2015)
    Cholangiocytes derived from human induced pluripotent stem cells for disease modeling and drug validation
    Nat Biotechnol, 33 (8), 845-852
    DOI 10.1038/nbt.3275, PubMed 26167629
  24. Schrumpf E, Boberg KM, Karlsen TH (2015)
    Primary sclerosing cholangitis - the Norwegian experience
    Scand J Gastroenterol, 50 (6), 781-96
    DOI 10.3109/00365521.2015.1028996, PubMed 25866138
  25. Schrumpf E, Tan C, Karlsen TH, Sponheim J, Björkström NK, Sundnes O, Alfsnes K, Kaser A, Jefferson DM, Ueno Y, Eide TJ, Haraldsen G, Zeissig S, Exley MA, Blumberg RS, Melum E (2015)
    The biliary epithelium presents antigens to and activates natural killer T cells
    Hepatology, 62 (4), 1249-59
    DOI 10.1002/hep.27840, PubMed 25855031
  26. Stiksrud B, Nowak P, Nwosu FC, Kvale D, Thalme A, Sonnerborg A, Ueland PM, Holm K, Birkeland SE, Dahm AE, Sandset PM, Rudi K, Hov JR, Dyrhol-Riise AM, Trøseid M (2015)
    Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART
    J Acquir Immune Defic Syndr, 70 (4), 329-37
    DOI 10.1097/QAI.0000000000000784, PubMed 26258571
  27. Thorsen T, Dahlgren US, Aandahl EM, Grzyb K, Karlsen TH, Boberg KM, Rydberg L, Naper C, Foss A, Bennet W (2015)
    Liver transplantation with deceased ABO-incompatible donors is life-saving but associated with increased risk of rejection and post-transplant complications
    Transpl Int, 28 (7), 800-12
    DOI 10.1111/tri.12552, PubMed 25736519
  28. Thorsen T, Aandahl EM, Bennet W, Olausson M, Ericzon BG, Nowak G, Duraj F, Isoniemi H, Rasmussen A, Karlsen TH, Foss A (2015)
    Transplantation With Livers From Deceased Donors Older Than 75 Years
    Transplantation, 99 (12), 2534-42
    DOI 10.1097/TP.0000000000000728, PubMed 25909464
  29. Vesterhus M, Hov JR, Holm A, Schrumpf E, Nygård S, Godang K, Andersen IM, Naess S, Thorburn D, Saffioti F, Vatn M, Gilja OH, Lund-Johansen F, Syversveen T, Brabrand K, Parés A, Ponsioen CY, Pinzani M, Färkkilä M, Moum B, Ueland T, Røsjø H, Rosenberg W, Boberg KM, Karlsen TH (2015)
    Enhanced liver fibrosis score predicts transplant-free survival in primary sclerosing cholangitis
    Hepatology, 62 (1), 188-97
    DOI 10.1002/hep.27825, PubMed 25833813
  30. Vukcevic D, Traherne JA, Næss S, Ellinghaus E, Kamatani Y, Dilthey A, Lathrop M, Karlsen TH, Franke A, Moffatt M, Cookson W, Trowsdale J, McVean G, Sawcer S, Leslie S (2015)
    Imputation of KIR Types from SNP Variation Data
    Am J Hum Genet, 97 (4), 593-607
    DOI 10.1016/j.ajhg.2015.09.005, PubMed 26430804
  31. Wannhoff A, Folseraas T, Brune M, Rupp C, Friedrich K, Knierim J, Weiss KH, Sauer P, Flechtenmacher C, Schirmacher P, Stremmel W, Hov JR, Gotthardt DN (2015)
    A common genetic variant of fucosyltransferase 2 correlates with serum carcinoembryonic antigen levels and affects cancer screening in patients with primary sclerosing cholangitis
    United European Gastroenterol J, 4 (1), 84-91
    DOI 10.1177/2050640615581577, PubMed 26966527
  32. Wittig M, Anmarkrud JA, Kässens JC, Koch S, Forster M, Ellinghaus E, Hov JR, Sauer S, Schimmler M, Ziemann M, Görg S, Jacob F, Karlsen TH, Franke A (2015)
    Development of a high-resolution NGS-based HLA-typing and analysis pipeline
    Nucleic Acids Res, 43 (11), e70
    DOI 10.1093/nar/gkv184, PubMed 25753671
  33. Åberg F, Gissler M, Karlsen TH, Ericzon BG, Foss A, Rasmussen A, Bennet W, Olausson M, Line PD, Nordin A, Bergquist A, Boberg KM, Castedal M, Pedersen CR, Isoniemi H (2015)
    Differences in long-term survival among liver transplant recipients and the general population: a population-based Nordic study
    Hepatology, 61 (2), 668-77
    DOI 10.1002/hep.27538, PubMed 25266201

Publications 2014

  1. Eskesen AN, Bjøro K, Aandahl EM, Line PD, Melum E (2014)
    Low use of surveillance and early diagnosis of hepatocellular carcinoma in Norway--a population-based cohort study
    Cancer Epidemiol, 38 (6), 741-7
    DOI 10.1016/j.canep.2014.10.005, PubMed 25454262
  2. Fickert P, Pollheimer MJ, Beuers U, Lackner C, Hirschfield G, Housset C, Keitel V, Schramm C, Marschall HU, Karlsen TH, Melum E, Kaser A, Eksteen B, Strazzabosco M, Manns M, Trauner M, International PSC Study Group (IPSCSG) (2014)
    Characterization of animal models for primary sclerosing cholangitis (PSC)
    J Hepatol, 60 (6), 1290-303
    DOI 10.1016/j.jhep.2014.02.006, PubMed 24560657
  3. Flachsbart F, Caliebe A, Heinsen FA, Hemming-Karlsen T, Schreiber S, Franke A, Nebel A (2014)
    Investigation of complement component C4 copy number variation in human longevity
    PLoS One, 9 (1), e86188
    DOI 10.1371/journal.pone.0086188, PubMed 24465950
  4. Fosby B, Næss S, Hov JR, Traherne J, Boberg KM, Trowsdale J, Foss A, Line PD, Franke A, Melum E, Scott H, Karlsen TH (2014)
    HLA variants related to primary sclerosing cholangitis influence rejection after liver transplantation
    World J Gastroenterol, 20 (14), 3986-4000
    DOI 10.3748/wjg.v20.i14.3986, PubMed 24744588
  5. Friedrich K, Wannhoff A, Kattner S, Brune M, Hov JR, Weiss KH, Antoni C, Dollinger M, Neumann-Haefelin C, Seufferlein T, Schemmer P, Schirmacher P, Stremmel W, Gotthardt DN (2014)
    PNPLA3 in end-stage liver disease: alcohol consumption, hepatocellular carcinoma development, and transplantation-free survival
    J Gastroenterol Hepatol, 29 (7), 1477-84
    DOI 10.1111/jgh.12540, PubMed 25273282
  6. Henriksen EK, Melum E, Karlsen TH (2014)
    Update on primary sclerosing cholangitis genetics
    Curr Opin Gastroenterol, 30 (3), 310-9
    DOI 10.1097/MOG.0000000000000052, PubMed 24565892
  7. Hirschfield GM, Karlsen TH (2014)
    Genetic risks link autoimmune hepatitis to other autoimmune liver disease
    Gastroenterology, 147 (2), 270-3
    DOI 10.1053/j.gastro.2014.06.020, PubMed 24973678
  8. Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS (2014)
    CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
    Nature, 517 (7534), 386-90
    DOI 10.1038/nature13848, PubMed 25363763
  9. Naess S, Björnsson E, Anmarkrud JA, Al Mamari S, Juran BD, Lazaridis KN, Chapman R, Bergquist A, Melum E, Marsh SG, Schrumpf E, Lie BA, Boberg KM, Karlsen TH, Hov JR (2014)
    Small duct primary sclerosing cholangitis without inflammatory bowel disease is genetically different from large duct disease
    Liver Int, 34 (10), 1488-95
    DOI 10.1111/liv.12492, PubMed 24517468
  10. Næss S, Lie BA, Melum E, Olsson M, Hov JR, Croucher PJ, Hampe J, Thorsby E, Bergquist A, Traherne JA, Schrumpf E, Boberg KM, Schreiber S, Franke A, Karlsen TH (2014)
    Refinement of the MHC risk map in a scandinavian primary sclerosing cholangitis population
    PLoS One, 9 (12), e114486
    DOI 10.1371/journal.pone.0114486, PubMed 25521205
  11. Rupp C, Friedrich K, Folseraas T, Wannhoff A, Bode KA, Weiss KH, Schirmacher P, Sauer P, Stremmel W, Gotthardt DN (2014)
    Fut2 genotype is a risk factor for dominant stenosis and biliary candida infections in primary sclerosing cholangitis
    Aliment Pharmacol Ther, 39 (8), 873-82
    DOI 10.1111/apt.12663, PubMed 24612312
  12. Vedeld HM, Andresen K, Eilertsen IA, Nesbakken A, Seruca R, Gladhaug IP, Thiis-Evensen E, Rognum TO, Boberg KM, Lind GE (2014)
    The novel colorectal cancer biomarkers CDO1, ZSCAN18 and ZNF331 are frequently methylated across gastrointestinal cancers
    Int J Cancer, 136 (4), 844-53
    DOI 10.1002/ijc.29039, PubMed 24948044
  13. Zeissig S, Petersen BS, Tomczak M, Melum E, Huc-Claustre E, Dougan SK, Laerdahl JK, Stade B, Forster M, Schreiber S, Weir D, Leichtner AM, Franke A, Blumberg RS (2014)
    Early-onset Crohn's disease and autoimmunity associated with a variant in CTLA-4
    Gut, 64 (12), 1889-97
    DOI 10.1136/gutjnl-2014-308541, PubMed 25367873

Publications 2013

  1. Andersen IM, Tengesdal G, Lie BA, Boberg KM, Karlsen TH, Hov JR (2013)
    Effects of coffee consumption, smoking, and hormones on risk for primary sclerosing cholangitis
    Clin Gastroenterol Hepatol, 12 (6), 1019-28
    DOI 10.1016/j.cgh.2013.09.024, PubMed 24076415
  2. Block M, Jørgensen KK, Oresland T, Lindholm E, Grzyb K, Cvancarova M, Vatn MH, Boberg KM, Börjesson L (2013)
    Colectomy for patients with ulcerative colitis and primary sclerosing cholangitis - what next?
    J Crohns Colitis, 8 (5), 421-30
    DOI 10.1016/j.crohns.2013.10.008, PubMed 24239402
  3. Ellinghaus D, Folseraas T, Holm K, Ellinghaus E, Melum E, Balschun T, Laerdahl JK, Shiryaev A, Gotthardt DN, Weismüller TJ, Schramm C, Wittig M, Bergquist A, Björnsson E, Marschall HU, Vatn M, Teufel A, Rust C, Gieger C, Wichmann HE, Runz H, Sterneck M, Rupp C, Braun F, Weersma RK et al. (2013)
    Genome-wide association analysis in primary sclerosing cholangitis and ulcerative colitis identifies risk loci at GPR35 and TCF4
    Hepatology, 58 (3), 1074-83
    DOI 10.1002/hep.25977, PubMed 22821403
  4. Ellinghaus D, Zhang H, Zeissig S, Lipinski S, Till A, Jiang T, Stade B, Bromberg Y, Ellinghaus E, Keller A, Rivas MA, Skieceviciene J, Doncheva NT, Liu X, Liu Q, Jiang F, Forster M, Mayr G, Albrecht M, Häsler R, Boehm BO, Goodall J, Berzuini CR, Lee J, Andersen V et al. (2013)
    Association between variants of PRDM1 and NDP52 and Crohn's disease, based on exome sequencing and functional studies
    Gastroenterology, 145 (2), 339-47
    DOI 10.1053/j.gastro.2013.04.040, PubMed 23624108
  5. Friedrich K, Rupp C, Hov JR, Steinebrunner N, Weiss KH, Stiehl A, Brune M, Schaefer PK, Schemmer P, Sauer P, Schirmacher P, Runz H, Karlsen TH, Stremmel W, Gotthardt DN (2013)
    A frequent PNPLA3 variant is a sex specific disease modifier in PSC patients with bile duct stenosis
    PLoS One, 8 (3), e58734
    DOI 10.1371/journal.pone.0058734, PubMed 23505555
  6. Hirschfield GM, Karlsen TH, Lindor KD, Adams DH (2013)
    Primary sclerosing cholangitis
    Lancet, 382 (9904), 1587-99
    DOI 10.1016/S0140-6736(13)60096-3, PubMed 23810223
  7. Jørgensen KK, Lindström L, Cvancarova M, Karlsen TH, Castedal M, Friman S, Schrumpf E, Foss A, Isoniemi H, Nordin A, Holte K, Rasmussen A, Bergquist A, Vatn MH, Boberg KM (2013)
    Immunosuppression after liver transplantation for primary sclerosing cholangitis influences activity of inflammatory bowel disease
    Clin Gastroenterol Hepatol, 11 (5), 517-23
    DOI 10.1016/j.cgh.2012.12.027, PubMed 23333218
  8. Karlsen TH, Boberg KM (2013)
    Update on primary sclerosing cholangitis
    J Hepatol, 59 (3), 571-82
    DOI 10.1016/j.jhep.2013.03.015, PubMed 23603668
  9. Karlsen TH, Vesterhus M, Boberg KM (2013)
    Review article: controversies in the management of primary biliary cirrhosis and primary sclerosing cholangitis
    Aliment Pharmacol Ther, 39 (3), 282-301
    DOI 10.1111/apt.12581, PubMed 24372568
  10. Kummen M, Schrumpf E, Boberg KM (2013)
    Liver abnormalities in bowel diseases
    Best Pract Res Clin Gastroenterol, 27 (4), 531-42
    DOI 10.1016/j.bpg.2013.06.013, PubMed 24090940
  11. Liu JZ, Hov JR, Folseraas T, Ellinghaus E, Rushbrook SM, Doncheva NT, Andreassen OA, Weersma RK, Weismüller TJ, Eksteen B, Invernizzi P, Hirschfield GM, Gotthardt DN, Pares A, Ellinghaus D, Shah T, Juran BD, Milkiewicz P, Rust C, Schramm C, Müller T, Srivastava B, Dalekos G, Nöthen MM, Herms S et al. (2013)
    Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis
    Nat Genet, 45 (6), 670-5
    DOI 10.1038/ng.2616, PubMed 23603763
  12. Mells GF, Kaser A, Karlsen TH (2013)
    Novel insights into autoimmune liver diseases provided by genome-wide association studies
    J Autoimmun, 46, 41-54
    DOI 10.1016/j.jaut.2013.07.004, PubMed 23931959
  13. Wannhoff A, Hov JR, Folseraas T, Rupp C, Friedrich K, Anmarkrud JA, Weiss KH, Sauer P, Schirmacher P, Boberg KM, Stremmel W, Karlsen TH, Gotthardt DN (2013)
    FUT2 and FUT3 genotype determines CA19-9 cut-off values for detection of cholangiocarcinoma in patients with primary sclerosing cholangitis
    J Hepatol, 59 (6), 1278-84
    DOI 10.1016/j.jhep.2013.08.005, PubMed 23958938

Publications 2012

  1. Andresen K, Boberg KM, Vedeld HM, Honne H, Hektoen M, Wadsworth CA, Clausen OP, Karlsen TH, Foss A, Mathisen O, Schrumpf E, Lothe RA, Lind GE (2012)
    Novel target genes and a valid biomarker panel identified for cholangiocarcinoma
    Epigenetics, 7 (11), 1249-57
    DOI 10.4161/epi.22191, PubMed 22983262
  2. Eskesen AN, Melum E, Moghaddam A, Bjøro K, Verbaan H, Ring-Larsen H, Dalgard O (2012)
    Genetic variants at the ITPA locus protect against ribavirin-induced hemolytic anemia and dose reduction in an HCV G2/G3 cohort
    Eur J Gastroenterol Hepatol, 24 (8), 890-6
    DOI 10.1097/MEG.0b013e3283546efd, PubMed 22584257
  3. Folseraas T, Melum E, Rausch P, Juran BD, Ellinghaus E, Shiryaev A, Laerdahl JK, Ellinghaus D, Schramm C, Weismüller TJ, Gotthardt DN, Hov JR, Clausen OP, Weersma RK, Janse M, Boberg KM, Björnsson E, Marschall HU, Cleynen I, Rosenstiel P, Holm K, Teufel A, Rust C, Gieger C, Wichmann HE et al. (2012)
    Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci
    J Hepatol, 57 (2), 366-75
    DOI 10.1016/j.jhep.2012.03.031, PubMed 22521342
  4. Forster M, Forster P, Elsharawy A, Hemmrich G, Kreck B, Wittig M, Thomsen I, Stade B, Barann M, Ellinghaus D, Petersen BS, May S, Melum E, Schilhabel MB, Keller A, Schreiber S, Rosenstiel P, Franke A (2012)
    From next-generation sequencing alignments to accurate comparison and validation of single-nucleotide variants: the pibase software
    Nucleic Acids Res, 41 (1), e16
    DOI 10.1093/nar/gks836, PubMed 22965131
  5. Fosby B, Karlsen TH, Melum E (2012)
    Recurrence and rejection in liver transplantation for primary sclerosing cholangitis
    World J Gastroenterol, 18 (1), 1-15
    DOI 10.3748/wjg.v18.i1.1, PubMed 22228965
  6. Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V et al. (2012)
    Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
    Nature, 491 (7422), 119-24
    DOI 10.1038/nature11582, PubMed 23128233
  7. Jørgensen KK, Lindström L, Cvancarova M, Castedal M, Friman S, Schrumpf E, Foss A, Isoniemi H, Nordin A, Holte K, Rasmussen A, Bergquist A, Vatn MH, Boberg KM (2012)
    Colorectal neoplasia in patients with primary sclerosing cholangitis undergoing liver transplantation: a Nordic multicenter study
    Scand J Gastroenterol, 47 (8-9), 1021-9
    DOI 10.3109/00365521.2012.685754, PubMed 22577871
  8. Karlsen TH (2012)
    A lecture on the genetics of primary sclerosing cholangitis
    Dig Dis, 30 Suppl 1, 32-8
    DOI 10.1159/000341122, PubMed 23075866
  9. Metzger J, Negm AA, Plentz RR, Weismüller TJ, Wedemeyer J, Karlsen TH, Dakna M, Mullen W, Mischak H, Manns MP, Lankisch TO (2012)
    Urine proteomic analysis differentiates cholangiocarcinoma from primary sclerosing cholangitis and other benign biliary disorders
    Gut, 62 (1), 122-30
    DOI 10.1136/gutjnl-2012-302047, PubMed 22580416
  10. Munk S, Dalsgaard J, Bjerggaard K, Andersen I, Hansen TB, Kehlet H (2012)
    Early recovery after fast-track Oxford unicompartmental knee arthroplasty. 35 patients with minimal invasive surgery
    Acta Orthop, 83 (1), 41-5
    DOI 10.3109/17453674.2012.657578, PubMed 22313368
  11. Næss S, Shiryaev A, Hov JR, Franke A, Karlsen TH (2012)
    Genetics in primary sclerosing cholangitis
    Clin Res Hepatol Gastroenterol, 36 (4), 325-33
    DOI 10.1016/j.clinre.2012.02.003, PubMed 22554879
  12. Srivastava B, Mells GF, Cordell HJ, Muriithi A, Brown M, Ellinghaus E, Franke A, UK-PSC Consortium, Karlsen TH, Sandford RN, Alexander GJ, Chapman RW, Rushbrook SM, Melum E (2012)
    Fine mapping and replication of genetic risk loci in primary sclerosing cholangitis
    Scand J Gastroenterol, 47 (7), 820-6
    DOI 10.3109/00365521.2012.682090, PubMed 22554193

Publications 2011

  1. Anderson CA, Boucher G, Lees CW, Franke A, D'Amato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagacé C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Colombel JF, Denson LA, De Vos M, Dubinsky M, Edwards C et al. (2011)
    Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
    Nat Genet, 43 (3), 246-52
    DOI 10.1038/ng.764, PubMed 21297633
  2. Boberg KM, Lind GE (2011)
    Primary sclerosing cholangitis and malignancy
    Best Pract Res Clin Gastroenterol, 25 (6), 753-64
    DOI 10.1016/j.bpg.2011.10.002, PubMed 22117640
  3. Folseraas T, Karlsen TH (2011)
    To MMP or not to MMP: a role for matrix metalloproteinase 3 in primary sclerosing cholangitis?
    Liver Int, 31 (6), 751-4
    DOI 10.1111/j.1478-3231.2011.02471.x, PubMed 21645205
  4. Folseraas T, Melum E, Franke A, Karlsen TH (2011)
    Genetics in primary sclerosing cholangitis
    Best Pract Res Clin Gastroenterol, 25 (6), 713-26
    DOI 10.1016/j.bpg.2011.09.010, PubMed 22117637
  5. Holm A, Wu W, Lund-Johansen F (2011)
    Antibody array analysis of labelled proteomes: how should we control specificity?
    N Biotechnol, 29 (5), 578-85
    DOI 10.1016/j.nbt.2011.07.008, PubMed 21840428
  6. Hov JR, Keitel V, Schrumpf E, Häussinger D, Karlsen TH (2011)
    TGR5 sequence variation in primary sclerosing cholangitis
    Dig Dis, 29 (1), 78-84
    DOI 10.1159/000324138, PubMed 21691110
  7. Hov JR, Kosmoliaptsis V, Traherne JA, Olsson M, Boberg KM, Bergquist A, Schrumpf E, Bradley JA, Taylor CJ, Lie BA, Trowsdale J, Karlsen TH (2011)
    Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis
    Hepatology, 53 (6), 1967-76
    DOI 10.1002/hep.24299, PubMed 21413052
  8. Janse M, Lamberts LE, Franke L, Raychaudhuri S, Ellinghaus E, Muri Boberg K, Melum E, Folseraas T, Schrumpf E, Bergquist A, Björnsson E, Fu J, Jan Westra H, Groen HJ, Fehrmann RS, Smolonska J, van den Berg LH, Ophoff RA, Porte RJ, Weismüller TJ, Wedemeyer J, Schramm C, Sterneck M, Günther R, Braun F et al. (2011)
    Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9
    Hepatology, 53 (6), 1977-85
    DOI 10.1002/hep.24307, PubMed 21425313
  9. Jørgensen KK, Grzyb K, Lundin KE, Clausen OP, Aamodt G, Schrumpf E, Vatn MH, Boberg KM (2011)
    Inflammatory bowel disease in patients with primary sclerosing cholangitis: clinical characterization in liver transplanted and nontransplanted patients
    Inflamm Bowel Dis, 18 (3), 536-45
    DOI 10.1002/ibd.21699, PubMed 21456044
  10. Karlsen TH, Kaser A (2011)
    Deciphering the genetic predisposition to primary sclerosing cholangitis
    Semin Liver Dis, 31 (2), 188-207
    DOI 10.1055/s-0031-1276647, PubMed 21538284
  11. Karlsen TH, Lazaridis KN (2011)
    At the end of the beginning. Foreword
    Semin Liver Dis, 31 (2), 111-3
    DOI 10.1055/s-0031-1276640, PubMed 21538278
  12. Moghaddam A, Melum E, Reinton N, Ring-Larsen H, Verbaan H, Bjøro K, Dalgard O (2011)
    IL28B genetic variation and treatment response in patients with hepatitis C virus genotype 3 infection
    Hepatology, 53 (3), 746-54
    DOI 10.1002/hep.24154, PubMed 21374656
  13. Naalsund A, Lund MB, Mynarek G, Aakhus S, Boberg KM, Nordøy I (2011)
    [A man in his 60s with severe respiratory failure]
    Tidsskr Nor Laegeforen, 131 (17), 1654-7
    DOI 10.4045/tidsskr.11.0110, PubMed 21901039
  14. Wiencke K, Boberg KM (2011)
    Current consensus on the management of primary sclerosing cholangitis
    Clin Res Hepatol Gastroenterol, 35 (12), 786-91
    DOI 10.1016/j.clinre.2011.04.007, PubMed 21963085

Publications 2010

  1. Boberg KM, Chapman RW, Hirschfield GM, Lohse AW, Manns MP, Schrumpf E, International Autoimmune Hepatitis Group (2010)
    Overlap syndromes: the International Autoimmune Hepatitis Group (IAIHG) position statement on a controversial issue
    J Hepatol, 54 (2), 374-85
    DOI 10.1016/j.jhep.2010.09.002, PubMed 21067838
  2. Bowlus CL, Li CS, Karlsen TH, Lie BA, Selmi C (2010)
    Primary sclerosing cholangitis in genetically diverse populations listed for liver transplantation: unique clinical and human leukocyte antigen associations
    Liver Transpl, 16 (11), 1324-30
    DOI 10.1002/lt.22161, PubMed 21031548
  3. Chapman R, Fevery J, Kalloo A, Nagorney DM, Boberg KM, Shneider B, Gores GJ, American Association for the Study of Liver Diseases (2010)
    Diagnosis and management of primary sclerosing cholangitis
    Hepatology, 51 (2), 660-78
    DOI 10.1002/hep.23294, PubMed 20101749
  4. Dolgos S, Hartmann A, Isaksen GA, Simonsen S, Bjørtuft Ø, Boberg KM, Bollerslev J (2010)
    Osteoporosis is a prevalent finding in patients with solid organ failure awaiting transplantation - a population based study
    Clin Transplant, 24 (5), E145-52
    DOI 10.1111/j.1399-0012.2010.01231.x, PubMed 20236290
  5. Ellinghaus E, Ellinghaus D, Stuart PE, Nair RP, Debrus S, Raelson JV, Belouchi M, Fournier H, Reinhard C, Ding J, Li Y, Tejasvi T, Gudjonsson J, Stoll SW, Voorhees JJ, Lambert S, Weidinger S, Eberlein B, Kunz M, Rahman P, Gladman DD, Gieger C, Wichmann HE, Karlsen TH, Mayr G et al. (2010)
    Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
    Nat Genet, 42 (11), 991-5
    DOI 10.1038/ng.689, PubMed 20953188
  6. Franke A, Balschun T, Sina C, Ellinghaus D, Häsler R, Mayr G, Albrecht M, Wittig M, Buchert E, Nikolaus S, Gieger C, Wichmann HE, Sventoraityte J, Kupcinskas L, Onnie CM, Gazouli M, Anagnou NP, Strachan D, McArdle WL, Mathew CG, Rutgeerts P, Vermeire S, Vatn MH, IBSEN study group, Krawczak M et al. (2010)
    Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL)
    Nat Genet, 42 (4), 292-4
    DOI 10.1038/ng.553, PubMed 20228798
  7. Friman S, Foss A, Isoniemi H, Olausson M, Höckerstedt K, Yamamoto S, Karlsen TH, Rizell M, Ericzon BG (2010)
    Liver transplantation for cholangiocarcinoma: selection is essential for acceptable results
    Scand J Gastroenterol, 46 (3), 370-5
    DOI 10.3109/00365521.2010.533384, PubMed 21073376
  8. Hollenbach JA, Meenagh A, Sleator C, Alaez C, Bengoche M, Canossi A, Contreras G, Creary L, Evseeva I, Gorodezky C, Hardie RA, Karlsen TH, Lie B, Luo M, Martinetti M, Navarette C, de Oliveira DC, Ozzella G, Pasi A, Pavlova E, Pinto S, Porto LC, Santos P, Slavcev A, Srinak D et al. (2010)
    Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA
    Tissue Antigens, 76 (1), 9-17
    DOI 10.1111/j.1399-0039.2010.01459.x, PubMed 20331834
  9. Holm K, Melum E, Franke A, Karlsen TH (2010)
    SNPexp - A web tool for calculating and visualizing correlation between HapMap genotypes and gene expression levels
    BMC Bioinformatics, 11, 600
    DOI 10.1186/1471-2105-11-600, PubMed 21167019
  10. Hov JR, Keitel V, Laerdahl JK, Spomer L, Ellinghaus E, ElSharawy A, Melum E, Boberg KM, Manke T, Balschun T, Schramm C, Bergquist A, Weismüller T, Gotthardt D, Rust C, Henckaerts L, Onnie CM, Weersma RK, Sterneck M, Teufel A, Runz H, Stiehl A, Ponsioen CY, Wijmenga C, Vatn MH et al. (2010)
    Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis
    PLoS One, 5 (8), e12403
    DOI 10.1371/journal.pone.0012403, PubMed 20811628
  11. Hov JR, Lleo A, Selmi C, Woldseth B, Fabris L, Strazzabosco M, Karlsen TH, Invernizzi P (2010)
    Genetic associations in Italian primary sclerosing cholangitis: heterogeneity across Europe defines a critical role for HLA-C
    J Hepatol, 52 (5), 712-7
    DOI 10.1016/j.jhep.2009.11.029, PubMed 20347497
  12. Karlsen TH, Hov JR (2010)
    Genetics of cholestatic liver disease in 2010
    Curr Opin Gastroenterol, 26 (3), 251-8
    DOI 10.1097/MOG.0b013e328336807d, PubMed 20042859
  13. Karlsen TH, Melum E, Franke A (2010)
    The utility of genome-wide association studies in hepatology
    Hepatology, 51 (5), 1833-42
    DOI 10.1002/hep.23564, PubMed 20232293
  14. Karlsen TH, Schrumpf E, Boberg KM (2010)
    Update on primary sclerosing cholangitis
    Dig Liver Dis, 42 (6), 390-400
    DOI 10.1016/j.dld.2010.01.011, PubMed 20172772
  15. Karlsen TH, Schrumpf E, Boberg KM (2010)
    Primary sclerosing cholangitis
    Best Pract Res Clin Gastroenterol, 24 (5), 655-66
    DOI 10.1016/j.bpg.2010.07.005, PubMed 20955968
  16. Lorentzen AR, Melum E, Ellinghaus E, Smestad C, Mero IL, Aarseth JH, Myhr KM, Celius EG, Lie BA, Karlsen TH, Franke A, Harbo HF (2010)
    Association to the Glypican-5 gene in multiple sclerosis
    J Neuroimmunol, 226 (1-2), 194-7
    DOI 10.1016/j.jneuroim.2010.07.003, PubMed 20692050
  17. Melum E, Franke A, Schramm C, Weismüller TJ, Gotthardt DN, Offner FA, Juran BD, Laerdahl JK, Labi V, Björnsson E, Weersma RK, Henckaerts L, Teufel A, Rust C, Ellinghaus E, Balschun T, Boberg KM, Ellinghaus D, Bergquist A, Sauer P, Ryu E, Hov JR, Wedemeyer J, Lindkvist B, Wittig M et al. (2010)
    Genome-wide association analysis in primary sclerosing cholangitis identifies two non-HLA susceptibility loci
    Nat Genet, 43 (1), 17-9
    DOI 10.1038/ng.728, PubMed 21151127
  18. Melum E, May S, Schilhabel MB, Thomsen I, Karlsen TH, Rosenstiel P, Schreiber S, Franke A (2010)
    SNP discovery performance of two second-generation sequencing platforms in the NOD2 gene region
    Hum Mutat, 31 (7), 875-85
    DOI 10.1002/humu.21276, PubMed 20506538
  19. Ponsioen CY, Reitsma JB, Boberg KM, Aabakken L, Rauws EA, Schrumpf E (2010)
    Validation of a cholangiographic prognostic model in primary sclerosing cholangitis
    Endoscopy, 42 (9), 742-7
    DOI 10.1055/s-0030-1255527, PubMed 20623444

Publications 2009

  1. Forsbring M, Vik ES, Dalhus B, Karlsen TH, Bergquist A, Schrumpf E, Bjørås M, Boberg KM, Alseth I (2009)
    Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma
    Carcinogenesis, 30 (7), 1147-54
    DOI 10.1093/carcin/bgp118, PubMed 19443904
  2. Karlsen TH (2009)
    Genome-wide association studies reach hepatology
    J Hepatol, 50 (6), 1278-80
    DOI 10.1016/j.jhep.2009.03.002, PubMed 19395112
  3. Karlsen TH, Franke A, Melum E, Kaser A, Hov JR, Balschun T, Lie BA, Bergquist A, Schramm C, Weismüller TJ, Gotthardt D, Rust C, Philipp EE, Fritz T, Henckaerts L, Weersma RK, Stokkers P, Ponsioen CY, Wijmenga C, Sterneck M, Nothnagel M, Hampe J, Teufel A, Runz H, Rosenstiel P et al. (2009)
    Genome-wide association analysis in primary sclerosing cholangitis
    Gastroenterology, 138 (3), 1102-11
    DOI 10.1053/j.gastro.2009.11.046, PubMed 19944697
  4. Lorentzen AR, Karlsen TH, Olsson M, Smestad C, Mero IL, Woldseth B, Sun JY, Senitzer D, Celius EG, Thorsby E, Spurkland A, Lie BA, Harbo HF (2009)
    Killer immunoglobulin-like receptor ligand HLA-Bw4 protects against multiple sclerosis
    Ann Neurol, 65 (6), 658-66
    DOI 10.1002/ana.21695, PubMed 19630074
  5. Melum E, Franke A, Karlsen TH (2009)
    Genome-wide association studies--a summary for the clinical gastroenterologist
    World J Gastroenterol, 15 (43), 5377-96
    DOI 10.3748/wjg.15.5377, PubMed 19916168
  6. Michalsen S, Schrumpf E, Beiske K, Tierens A, Stenberg V, Tjønnfjord GE (2009)
    [Large granular lymphocytic leukaemia]
    Tidsskr Nor Laegeforen, 129 (11), 1098-102
    DOI 10.4045/tidsskr.09.0152, PubMed 19488091
  7. Scholz T, Karlsen TH, Sanengen T, Schrumpf E, Line PD, Boberg KM, Jörgensen PF, Fosby B, Bentdal O, Ostensen AB, Osnes S, Riddervold F, Haugaa H, Hausken J, Bergmann JB, Foss S, Björo K, Foss A, Levertransplantasjonsgruppen ved Oslo universitetssykehus, Rikshospitalet (2009)
    [Liver transplantation in Norway through 25 years]
    Tidsskr Nor Laegeforen, 129 (24), 2587-92
    DOI 10.4045/tidsskr.09.1106, PubMed 20029553
  8. Yu X, Wieczorek S, Franke A, Yin H, Pierer M, Sina C, Karlsen TH, Boberg KM, Bergquist A, Kunz M, Witte T, Gross WL, Epplen JT, Alarcón-Riquelme ME, Schreiber S, Ibrahim SM (2009)
    Association of UCP2 -866 G/A polymorphism with chronic inflammatory diseases
    Genes Immun, 10 (6), 601-5
    DOI 10.1038/gene.2009.29, PubMed 19387457

Publications 2008

  1. Björnsson E, Olsson R, Bergquist A, Lindgren S, Braden B, Chapman RW, Boberg KM, Angulo P (2008)
    The natural history of small-duct primary sclerosing cholangitis
    Gastroenterology, 134 (4), 975-80
    DOI 10.1053/j.gastro.2008.01.042, PubMed 18395078
  2. Franke A, Balschun T, Karlsen TH, Hedderich J, May S, Lu T, Schuldt D, Nikolaus S, Rosenstiel P, Krawczak M, Schreiber S (2008)
    Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
    Nat Genet, 40 (6), 713-5
    DOI 10.1038/ng.148, PubMed 18438405
  3. Franke A, Balschun T, Karlsen TH, Sventoraityte J, Nikolaus S, Mayr G, Domingues FS, Albrecht M, Nothnagel M, Ellinghaus D, Sina C, Onnie CM, Weersma RK, Stokkers PC, Wijmenga C, Gazouli M, Strachan D, McArdle WL, Vermeire S, Rutgeerts P, Rosenstiel P, Krawczak M, Vatn MH, IBSEN study group, Mathew CG et al. (2008)
    Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
    Nat Genet, 40 (11), 1319-23
    DOI 10.1038/ng.221, PubMed 18836448
  4. Hennes EM, Zeniya M, Czaja AJ, Parés A, Dalekos GN, Krawitt EL, Bittencourt PL, Porta G, Boberg KM, Hofer H, Bianchi FB, Shibata M, Schramm C, Eisenmann de Torres B, Galle PR, McFarlane I, Dienes HP, Lohse AW, International Autoimmune Hepatitis Group (2008)
    Simplified criteria for the diagnosis of autoimmune hepatitis
    Hepatology, 48 (1), 169-76
    DOI 10.1002/hep.22322, PubMed 18537184
  5. Hov JR, Boberg KM, Karlsen TH (2008)
    Autoantibodies in primary sclerosing cholangitis
    World J Gastroenterol, 14 (24), 3781-91
    DOI 10.3748/wjg.14.3781, PubMed 18609700
  6. Karlsen TH, Schrumpf E, Boberg KM (2008)
    Gallbladder polyps in primary sclerosing cholangitis: not so benign
    Curr Opin Gastroenterol, 24 (3), 395-9
    DOI 10.1097/MOG.0b013e3282f5727a, PubMed 18408471
  7. Melum E, Buch S, Schafmayer C, Kalthoff H, Tepel J, Schreiber S, Karlsen TH, Hampe J (2008)
    Investigation of cholangiocarcinoma associated NKG2D polymorphisms in colorectal carcinoma
    Int J Cancer, 123 (1), 241-2
    DOI 10.1002/ijc.23517, PubMed 18398827
  8. Melum E, Karlsen TH, Bergquist A, Schrumpf E, Boberg KM (2008)
    An interleukin-6 (IL-6) receptor polymorphism affecting serum levels of IL-6 does not increase the risk of cholangiocarcinoma in primary sclerosing cholangitis
    Am J Gastroenterol, 103 (4), 1045; author reply 1045-6
    DOI 10.1111/j.1572-0241.2007.01772_5.x, PubMed 18397431
  9. Melum E, Karlsen TH, Schrumpf E, Bergquist A, Thorsby E, Boberg KM, Lie BA (2008)
    Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms
    Hepatology, 47 (1), 90-6
    DOI 10.1002/hep.21964, PubMed 18023027

Page visits: 10313