Divison of Cancer Medicine Last 100 publications from major journals with first or last author from OUS
Transcription termination counteracts DNA damage after WEE1 inhibition
Nucleic Acids Res, 54 (3)
DOI 10.1093/nar/gkaf1487, PubMed 41569153
Multiomics Profiling of T-cell Leukemia and Lymphoma Enables Targeted Therapeutic Discovery
Cancer Res, 86 (2), 295-309
DOI 10.1158/0008-5472.CAN-25-0881, PubMed 41166698
High-Risk Stage II Melanoma: AJCC Staging anomaly or understaging dilemma?
Br J Dermatol (in press)
DOI 10.1093/bjd/ljaf523, PubMed 41483011
Optimizing lenalidomide therapy in renal impairment: analysis of renal response in the prospective REMNANT study in transplant-eligible newly diagnosed multiple myeloma
Blood Cancer J, 15 (1), 214
DOI 10.1038/s41408-025-01407-5, PubMed 41429779
Targeting the unfolded protein response for cancer therapy: mitigating tumor adaptation and immune suppression
Biomark Res, 13 (1), 156
DOI 10.1186/s40364-025-00813-y, PubMed 41372991
Optimizing [212Pb]Pb-AB001 Radiopharmaceutical Therapy Schedules in PSMA-Positive Subcutaneous Prostate Cancer Xenografts
J Nucl Med, 66 (12), 1956-1963
DOI 10.2967/jnumed.125.270444, PubMed 41043994
SISAQOL-IMI consensus-based guidelines to design, analyse, interpret, and present patient-reported outcomes in cancer clinical trials
Lancet Oncol, 26 (12), e683-e693
DOI 10.1016/S1470-2045(25)00520-0, PubMed 41308689
Improved analysis of in vivo drug combination experiments with a comprehensive statistical framework and web-tool
Nat Commun, 16 (1), 10151
DOI 10.1038/s41467-025-65218-9, PubMed 41258298
Accelerating precision oncology by converging pragmatic trials and real-world evidence
Nat Rev Drug Discov, 24 (11), 809-810
DOI 10.1038/d41573-025-00047-5, PubMed 40082591
Navigating the landscape of protein folding and proteostasis: from molecular chaperones to therapeutic innovations
Signal Transduct Target Ther, 10 (1), 358
DOI 10.1038/s41392-025-02439-w, PubMed 41130962
Ex vivo correction of severe coagulation Factor VII deficiency in patient-derived 3D liver organoids
Haematologica (in press)
DOI 10.3324/haematol.2025.288046, PubMed 41063698
V-ATPase assembly at leaky lysosomes
Nat Struct Mol Biol, 32 (10), 1862-1864
DOI 10.1038/s41594-025-01612-7, PubMed 40646311
Re: Thomas Dreyer, Simone Brandt, Knud Fabrin, et al. Use of the Xpert Bladder Cancer Monitor Urinary Biomarker Test for Guiding Cystoscopy in High-grade Non-muscle-invasive Bladder Cancer: Results from the Randomized Controlled DaBlaCa-15 Trial. Eur Urol 2025;88:23-30
Eur Urol, 88 (6), e121
DOI 10.1016/j.eururo.2025.07.028, PubMed 40998632
Rewiring natural killer cells for next-generation cancer therapies
Cancer Cell, 43 (11), 1980-1982
DOI 10.1016/j.ccell.2025.08.007, PubMed 40972573
Pan-carcinoma sialyl-Tn-targeting expands CAR therapy to solid tumors
Cell Rep Med, 6 (9), 102350
DOI 10.1016/j.xcrm.2025.102350, PubMed 40925376
Use of upfront autologous stem cell transplantation in myeloma patients aged >65 years: a population-based study by the Nordic Myeloma Study Group
Haematologica (in press)
DOI 10.3324/haematol.2025.287344, PubMed 40905090
TCR-engineered T cells targeting a shared β-catenin mutation eradicate solid tumors
Nat Immunol, 26 (10), 1726-1736
DOI 10.1038/s41590-025-02252-1, PubMed 40866620
Targeting the roots of myeloid malignancies with T cell receptors
Nat Rev Cancer, 25 (12), 965-985
DOI 10.1038/s41568-025-00857-0, PubMed 40841587
IFN-γ is a direct driver of crypt hyperplasia in celiac disease
J Clin Invest, 135 (20)
DOI 10.1172/JCI194858, PubMed 40828615
Brentuximab vedotin, cyclophosphamide, doxorubicin, and prednisone for advanced-stage Hodgkin lymphoma in older patients
Hemasphere, 9 (8), e70190
DOI 10.1002/hem3.70190, PubMed 40832013
Can radiology be first to use prognostic deep learning models for oncological treatment?
Ann Oncol, 36 (10), 1119-1122
DOI 10.1016/j.annonc.2025.07.013, PubMed 40754034
Lysosomal membrane homeostasis and its importance in physiology and disease
Nat Rev Mol Cell Biol, 27 (1), 71-87
DOI 10.1038/s41580-025-00873-w, PubMed 40759742
Proteasome inhibition overcomes resistance to targeted therapies in B-cell malignancy models and in an index patient
Cell Death Dis, 16 (1), 555
DOI 10.1038/s41419-025-07884-7, PubMed 40701968
A Machine Learning-Based Strategy Predicts Selective and Synergistic Drug Combinations for Relapsed Acute Myeloid Leukemia
Cancer Res, 85 (14), 2753-2768
DOI 10.1158/0008-5472.CAN-24-3840, PubMed 40354625
Endoplasmic reticulum stress-driven nucleotide catabolism fuels prostate cancer
Cancer Lett, 630, 217888
DOI 10.1016/j.canlet.2025.217888, PubMed 40617554
Improved detection of lipidated Atg8a by immunoblotting in Drosophila melanogaster cells and tissues enables precise investigation of Atg8a flux and its termination
Autophagy, 21 (11), 2497-2517
DOI 10.1080/15548627.2025.2508551, PubMed 40426043
STEAP1: a promising target in prostate cancer therapy
Trends Cancer, 11 (8), 722-725
DOI 10.1016/j.trecan.2025.05.007, PubMed 40527692
Response to Comment on: "A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma"
Haematologica, 110 (11), 2866-2867
DOI 10.3324/haematol.2025.288284, PubMed 40501391
Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation
Gut, 74 (7), 1125-1136
DOI 10.1136/gutjnl-2024-334148, PubMed 39832892
The expanding repertoire of ESCRT functions in cell biology and disease
Nature, 642 (8069), 877-888
DOI 10.1038/s41586-025-08950-y, PubMed 40562928
The innate power of natural killer cells in cancer therapy
Nat Med, 31 (6), 1755-1756
DOI 10.1038/s41591-025-03712-9, PubMed 40355615
Therapeutic evaluation of [212Pb]Pb-AB001 and [177Lu]Lu-PSMA-617 in a mouse model of disseminated prostate cancer
Eur J Nucl Med Mol Imaging, 52 (13), 4847-4859
DOI 10.1007/s00259-025-07330-y, PubMed 40397137
Protein Profiles Predict Treatment Responses to the PI3K Inhibitor Umbralisib in Patients with Chronic Lymphocytic Leukemia
Clin Cancer Res, 31 (10), 1943-1955
DOI 10.1158/1078-0432.CCR-24-2911, PubMed 40085050
Biomarker-adapted treatment in high-risk large B-cell lymphoma
Hemasphere, 9 (5), e70139
DOI 10.1002/hem3.70139, PubMed 40357216
SNX10 at the crossroad of endocytosis and piecemeal mitophagy
Autophagy, 21 (9), 2077-2079
DOI 10.1080/15548627.2025.2499641, PubMed 40327657
Highly sensitive method captures rare RNAs in blood to search for disease
Nature, 641 (8063), 599-600
DOI 10.1038/d41586-025-01127-7, PubMed 40240820
First-in-Human Phase 0 Study of AB001, a Prostate-Specific Membrane Antigen-Targeted 212Pb Radioligand, in Patients with Metastatic Castration-Resistant Prostate Cancer
J Nucl Med, 66 (5), 732-738
DOI 10.2967/jnumed.124.269299, PubMed 40081958
A simplified frailty score predicts outcome in curatively treated older patients with classical Hodgkin lymphoma
Haematologica, 110 (10), 2356-2366
DOI 10.3324/haematol.2025.287509, PubMed 40270216
Re: Histopathologic Features and Transcriptomic Signatures Do Not Solve the Issue of Magnetic Resonance Imaging-invisible Prostate Cancers: A Matched-pair Analysis
Eur Urol, 88 (2), 215-216
DOI 10.1016/j.eururo.2025.04.002, PubMed 40222874
A balancing ACT: maximizing the benefits of appropriate brain radiation therapy-authors' reply
Lancet Reg Health Eur, 52, 101291
DOI 10.1016/j.lanepe.2025.101291, PubMed 40247950
Oncological and Survival Endpoints in Cancer Cachexia Clinical Trials: Systematic Review 6 of the Cachexia Endpoints Series
J Cachexia Sarcopenia Muscle, 16 (2), e13756
DOI 10.1002/jcsm.13756, PubMed 40065459
Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database
Br J Surg, 112 (4)
DOI 10.1093/bjs/znaf061, PubMed 40231433
Molecular prognostic factors for liver transplantation of unresectable metastatic colorectal cancer
Br J Surg, 112 (4)
DOI 10.1093/bjs/znaf072, PubMed 40235343
Brentuximab vedotin monotherapy is a feasible and effective treatment for older patients with classical Hodgkin lymphoma unsuitable for curative chemotherapy: Results from the prospective GHSG-NLG phase II BVB trial
Hemasphere, 9 (3), e70099
DOI 10.1002/hem3.70099, PubMed 40124718
Computational drug repurposing: approaches, evaluation of in silico resources and case studies
Nat Rev Drug Discov, 24 (7), 521-542
DOI 10.1038/s41573-025-01164-x, PubMed 40102635
Challenges in capturing the mycobiome from shotgun metagenome data: lack of software and databases
Microbiome, 13 (1), 66
DOI 10.1186/s40168-025-02048-3, PubMed 40055808
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective
J Extracell Vesicles, 14 (3), e70049
DOI 10.1002/jev2.70049, PubMed 40091364
Characterization of Screening Strategies for Lynch Syndrome in Latin America
Clin Gastroenterol Hepatol, 23 (9), 1642-1654
DOI 10.1016/j.cgh.2024.12.026, PubMed 40010418
FuSViz-visualization and interpretation of structural variation using cancer genomics and transcriptomics data
Nucleic Acids Res, 53 (4)
DOI 10.1093/nar/gkaf078, PubMed 39995037
Isatuximab, bortezomib, lenalidomide, and limited dexamethasone in patients with transplant-ineligible multiple myeloma (REST): a multicentre, single-arm, phase 2 trial
Lancet Haematol, 12 (2), e120-e127
DOI 10.1016/S2352-3026(24)00347-8, PubMed 39909655
Deep Learning Model for Predicting Immunotherapy Response in Advanced Non-Small Cell Lung Cancer
JAMA Oncol, 11 (2), 109-118
DOI 10.1001/jamaoncol.2024.5356, PubMed 39724105
Safety and efficacy of the therapeutic DNA-based vaccine VB10.16 in combination with atezolizumab in persistent, recurrent or metastatic HPV16-positive cervical cancer: a multicenter, single-arm phase 2a study
J Immunother Cancer, 13 (1)
DOI 10.1136/jitc-2024-010827, PubMed 39773564
Survival and quality of life after first-time diagnosis of brain metastases: a multicenter, prospective, observational study
Lancet Reg Health Eur, 49, 101181
DOI 10.1016/j.lanepe.2024.101181, PubMed 39807153
Co-occurring mutations identify prognostic subgroups of microsatellite stable colorectal cancer
Mol Cancer, 23 (1), 264
DOI 10.1186/s12943-024-02173-x, PubMed 39587554
Immunological facets of prostate cancer and the potential of immune checkpoint inhibition in disease management
Theranostics, 14 (18), 6913-6934
DOI 10.7150/thno.100555, PubMed 39629128
Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor
Med, 6 (2), 100521
DOI 10.1016/j.medj.2024.09.010, PubMed 39423821
Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer
Nat Commun, 15 (1), 8895
DOI 10.1038/s41467-024-53039-1, PubMed 39406723
Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones
Nat Commun, 15 (1), 8579
DOI 10.1038/s41467-024-52980-5, PubMed 39362905
Pitfalls in lipid mass spectrometry of mammalian samples - a brief guide for biologists
Nat Rev Mol Cell Biol, 25 (10), 759-760
DOI 10.1038/s41580-024-00758-4, PubMed 38951702
PI3K Inhibitors in Hematology: When One Door Closes…
Clin Cancer Res, 30 (17), 3667-3675
DOI 10.1158/1078-0432.CCR-24-0967, PubMed 38967552
Exosome regulation by Rubicon in ageing
Nat Cell Biol, 26 (9), 1380-1381
DOI 10.1038/s41556-024-01482-z, PubMed 39174741
Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
Blood Cancer J, 14 (1), 147
DOI 10.1038/s41408-024-01124-5, PubMed 39191762
Outcome prediction based on [18F]FDG PET/CT in patients with pleural mesothelioma treated with ipilimumab and nivolumab +/- UV1 telomerase vaccine
Eur J Nucl Med Mol Imaging, 52 (2), 693-707
DOI 10.1007/s00259-024-06853-0, PubMed 39133306
Prognostic genome and transcriptome signatures in colorectal cancers
Nature, 633 (8028), 137-146
DOI 10.1038/s41586-024-07769-3, PubMed 39112715
From sweat to hope: The role of exercise-induced extracellular vesicles in cancer prevention and treatment
J Extracell Vesicles, 13 (8), e12500
DOI 10.1002/jev2.12500, PubMed 39183543
Author Correction: IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Nat Commun, 15 (1), 6190
DOI 10.1038/s41467-024-50645-x, PubMed 39043728
Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
Cell Stem Cell, 31 (9), 1376-1386.e8
DOI 10.1016/j.stem.2024.06.011, PubMed 38981470
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
Nat Immunol, 25 (8), 1445-1459
DOI 10.1038/s41590-024-01884-z, PubMed 38956379
Health-related quality of life in relapsed/refractory multiple myeloma treated with melflufen and dexamethasone: analyses from the phase III OCEAN study
Haematologica, 109 (7), 2331-2336
DOI 10.3324/haematol.2023.284635, PubMed 38426292
Egr2 to the rescue: nanoparticles revitalize natural killer cells in the fight against cancer
EMBO J, 43 (13), 2527-2529
DOI 10.1038/s44318-024-00144-y, PubMed 38886578
B7-H3: a robust target for immunotherapy in prostate cancer
Trends Cancer, 10 (7), 584-587
DOI 10.1016/j.trecan.2024.05.003, PubMed 38839545
Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancer
Nat Commun, 15 (1), 4342
DOI 10.1038/s41467-024-48706-2, PubMed 38773143
CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
Cell Rep Med, 5 (6), 101572
DOI 10.1016/j.xcrm.2024.101572, PubMed 38754420
Overall survival and causes of death in elderly patients with Hodgkin lymphoma: a Norwegian population-based case-control study
Haematologica, 109 (5), 1403-1412
DOI 10.3324/haematol.2023.283721, PubMed 37881879
Engineering immune-evasive allogeneic cellular immunotherapies
Nat Rev Immunol, 24 (9), 680-693
DOI 10.1038/s41577-024-01022-8, PubMed 38658708
In multiple myeloma, monthly treatment with zoledronic acid beyond two years offers sustained protection against progressive bone disease
Blood Cancer J, 14 (1), 65
DOI 10.1038/s41408-024-01046-2, PubMed 38622134
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
J Immunother Cancer, 12 (4)
DOI 10.1136/jitc-2023-008179, PubMed 38604812
VRD versus VCD as induction therapy before autologous stem cell transplantation in multiple myeloma: a nationwide population-based study
Blood Cancer J, 14 (1), 60
DOI 10.1038/s41408-024-01047-1, PubMed 38594252
Transient TCR-based T cell therapy in a patient with advanced treatment-resistant MSI-high colorectal cancer
Mol Ther, 32 (6), 2021-2029
DOI 10.1016/j.ymthe.2024.04.009, PubMed 38582964
Incidence and Factors Associated With Second Primary Invasive Melanoma in Norway
JAMA Dermatol, 160 (4), 402-408
DOI 10.1001/jamadermatol.2023.6251, PubMed 38416466
Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series
J Cachexia Sarcopenia Muscle, 15 (3), 794-815
DOI 10.1002/jcsm.13453, PubMed 38553255
A dual-purpose fusion complex in autophagy
Cell Res, 34 (3), 183-184
DOI 10.1038/s41422-023-00925-w, PubMed 38228880
Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
Nat Commun, 15 (1), 1791
DOI 10.1038/s41467-024-46033-0, PubMed 38424056
Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
Nat Commun, 15 (1), 1277
DOI 10.1038/s41467-024-45558-8, PubMed 38341434
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature
Biochim Biophys Acta Rev Cancer, 1879 (2), 189080
DOI 10.1016/j.bbcan.2024.189080, PubMed 38272101
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
J Immunother Cancer, 12 (1)
DOI 10.1136/jitc-2023-007990, PubMed 38242720
Lysophagy prevents neurotoxic aggregate transmission
Proc Natl Acad Sci U S A, 121 (3), e2321181121
DOI 10.1073/pnas.2321181121, PubMed 38190545
Sudarshan Kriya Yoga Breathing and a Meditation Program for Burnout Among Physicians: A Randomized Clinical Trial
JAMA Netw Open, 7 (1), e2353978
DOI 10.1001/jamanetworkopen.2023.53978, PubMed 38294813
ATPase-regulated autophagosome biogenesis
Autophagy, 20 (1), 218-219
DOI 10.1080/15548627.2023.2255967, PubMed 37722386
Robust scoring of selective drug responses for patient-tailored therapy selection
Nat Protoc, 19 (1), 60-82
DOI 10.1038/s41596-023-00903-x, PubMed 37996540
Removal of hypersignaling endosomes by simaphagy
Autophagy, 20 (4), 769-791
DOI 10.1080/15548627.2023.2267958, PubMed 37840274
Adipose-Derived Stromal Cells Preserve Pancreatic Islet Function in a Transplantable 3D Bioprinted Scaffold
Adv Healthc Mater, 12 (32), e2300640
DOI 10.1002/adhm.202300640, PubMed 37781993
Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
EBioMedicine, 97, 104829
DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Nat Cancer, 4 (10), 1474-1490
DOI 10.1038/s43018-023-00642-8, PubMed 37783807
Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligation
EBioMedicine, 96, 104811
DOI 10.1016/j.ebiom.2023.104811, PubMed 37741009
Adverse health outcomes and global quality of life in long-term testicular cancer survivors: a longitudinal 30-year perspective
Ann Oncol, 34 (12), 1165-1174
DOI 10.1016/j.annonc.2023.09.3101, PubMed 37739265
The separate axes of TECPR1 and ATG16L1 in CASM
Autophagy, 20 (1), 214-215
DOI 10.1080/15548627.2023.2255462, PubMed 37676042
The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
Haematologica, 108 (9), 2454-2466
DOI 10.3324/haematol.2022.282289, PubMed 36861406
Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
Clin Cancer Res, 29 (16), 3026-3036
DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632
Intensifying treatment in PET-positive multiple myeloma patients after upfront autologous stem cell transplantation
Leukemia, 37 (10), 2107-2114
DOI 10.1038/s41375-023-01998-7, PubMed 37568010