Divison of Cancer Medicine Last 100 publications from major journals with first or last author from OUS
Highly sensitive method captures rare RNAs in blood to search for disease
Nature (in press)
DOI 10.1038/d41586-025-01127-7, PubMed 40240820
Re: Histopathologic Features and Transcriptomic Signatures Do Not Solve the Issue of Magnetic Resonance Imaging-invisible Prostate Cancers: A Matched-pair Analysis
Eur Urol (in press)
DOI 10.1016/j.eururo.2025.04.002, PubMed 40222874
A balancing ACT: maximizing the benefits of appropriate brain radiation therapy-authors' reply
Lancet Reg Health Eur, 52, 101291
DOI 10.1016/j.lanepe.2025.101291, PubMed 40247950
Oncological and Survival Endpoints in Cancer Cachexia Clinical Trials: Systematic Review 6 of the Cachexia Endpoints Series
J Cachexia Sarcopenia Muscle, 16 (2), e13756
DOI 10.1002/jcsm.13756, PubMed 40065459
Molecular prognostic factors for liver transplantation of unresectable metastatic colorectal cancer
Br J Surg, 112 (4)
DOI 10.1093/bjs/znaf072, PubMed 40235343
Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database
Br J Surg, 112 (4)
DOI 10.1093/bjs/znaf061, PubMed 40231433
Brentuximab vedotin monotherapy is a feasible and effective treatment for older patients with classical Hodgkin lymphoma unsuitable for curative chemotherapy: Results from the prospective GHSG-NLG phase II BVB trial
Hemasphere, 9 (3), e70099
DOI 10.1002/hem3.70099, PubMed 40124718
Computational drug repurposing: approaches, evaluation of in silico resources and case studies
Nat Rev Drug Discov (in press)
DOI 10.1038/s41573-025-01164-x, PubMed 40102635
Protein profiles predict treatment responses to the PI3K inhibitor umbralisib in patients with chronic lymphocytic leukemia
Clin Cancer Res (in press)
DOI 10.1158/1078-0432.CCR-24-2911, PubMed 40085050
Accelerating precision oncology by converging pragmatic trials and real-world evidence
Nat Rev Drug Discov (in press)
DOI 10.1038/d41573-025-00047-5, PubMed 40082591
First-in-Human Phase 0 Study of AB001, a Prostate-Specific Membrane Antigen-Targeted 212Pb Radioligand, in Patients with Metastatic Castration-Resistant Prostate Cancer
J Nucl Med (in press)
DOI 10.2967/jnumed.124.269299, PubMed 40081958
Challenges in capturing the mycobiome from shotgun metagenome data: lack of software and databases
Microbiome, 13 (1), 66
DOI 10.1186/s40168-025-02048-3, PubMed 40055808
Quantitative Lipid Analysis of Extracellular Vesicle Preparations: A Perspective
J Extracell Vesicles, 14 (3), e70049
DOI 10.1002/jev2.70049, PubMed 40091364
Characterization of Screening Strategies for Lynch Syndrome in Latin America
Clin Gastroenterol Hepatol (in press)
DOI 10.1016/j.cgh.2024.12.026, PubMed 40010418
FuSViz-visualization and interpretation of structural variation using cancer genomics and transcriptomics data
Nucleic Acids Res, 53 (4)
DOI 10.1093/nar/gkaf078, PubMed 39995037
Isatuximab, bortezomib, lenalidomide, and limited dexamethasone in patients with transplant-ineligible multiple myeloma (REST): a multicentre, single-arm, phase 2 trial
Lancet Haematol, 12 (2), e120-e127
DOI 10.1016/S2352-3026(24)00347-8, PubMed 39909655
Deep Learning Model for Predicting Immunotherapy Response in Advanced Non-Small Cell Lung Cancer
JAMA Oncol, 11 (2), 109-118
DOI 10.1001/jamaoncol.2024.5356, PubMed 39724105
Unlocking novel T cell-based immunotherapy for hepatocellular carcinoma through neoantigen-driven T cell receptor isolation
Gut (in press)
DOI 10.1136/gutjnl-2024-334148, PubMed 39832892
Safety and efficacy of the therapeutic DNA-based vaccine VB10.16 in combination with atezolizumab in persistent, recurrent or metastatic HPV16-positive cervical cancer: a multicenter, single-arm phase 2a study
J Immunother Cancer, 13 (1)
DOI 10.1136/jitc-2024-010827, PubMed 39773564
Survival and quality of life after first-time diagnosis of brain metastases: a multicenter, prospective, observational study
Lancet Reg Health Eur, 49, 101181
DOI 10.1016/j.lanepe.2024.101181, PubMed 39807153
Co-occurring mutations identify prognostic subgroups of microsatellite stable colorectal cancer
Mol Cancer, 23 (1), 264
DOI 10.1186/s12943-024-02173-x, PubMed 39587554
Immunological facets of prostate cancer and the potential of immune checkpoint inhibition in disease management
Theranostics, 14 (18), 6913-6934
DOI 10.7150/thno.100555, PubMed 39629128
Targeting HLA-E-overexpressing cancers with a NKG2A/C switch receptor
Med, 6 (2), 100521
DOI 10.1016/j.medj.2024.09.010, PubMed 39423821
Targeting IRE1α reprograms the tumor microenvironment and enhances anti-tumor immunity in prostate cancer
Nat Commun, 15 (1), 8895
DOI 10.1038/s41467-024-53039-1, PubMed 39406723
Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones
Nat Commun, 15 (1), 8579
DOI 10.1038/s41467-024-52980-5, PubMed 39362905
Pitfalls in lipid mass spectrometry of mammalian samples - a brief guide for biologists
Nat Rev Mol Cell Biol, 25 (10), 759-760
DOI 10.1038/s41580-024-00758-4, PubMed 38951702
PI3K Inhibitors in Hematology: When One Door Closes…
Clin Cancer Res, 30 (17), 3667-3675
DOI 10.1158/1078-0432.CCR-24-0967, PubMed 38967552
Exosome regulation by Rubicon in ageing
Nat Cell Biol, 26 (9), 1380-1381
DOI 10.1038/s41556-024-01482-z, PubMed 39174741
Multi-omics profiling of longitudinal samples reveals early genomic changes in follicular lymphoma
Blood Cancer J, 14 (1), 147
DOI 10.1038/s41408-024-01124-5, PubMed 39191762
Outcome prediction based on [18F]FDG PET/CT in patients with pleural mesothelioma treated with ipilimumab and nivolumab +/- UV1 telomerase vaccine
Eur J Nucl Med Mol Imaging, 52 (2), 693-707
DOI 10.1007/s00259-024-06853-0, PubMed 39133306
Prognostic genome and transcriptome signatures in colorectal cancers
Nature, 633 (8028), 137-146
DOI 10.1038/s41586-024-07769-3, PubMed 39112715
From sweat to hope: The role of exercise-induced extracellular vesicles in cancer prevention and treatment
J Extracell Vesicles, 13 (8), e12500
DOI 10.1002/jev2.12500, PubMed 39183543
Author Correction: IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Nat Commun, 15 (1), 6190
DOI 10.1038/s41467-024-50645-x, PubMed 39043728
Genetic ablation of adhesion ligands mitigates rejection of allogeneic cellular immunotherapies
Cell Stem Cell, 31 (9), 1376-1386.e8
DOI 10.1016/j.stem.2024.06.011, PubMed 38981470
Pan-cancer profiling of tumor-infiltrating natural killer cells through transcriptional reference mapping
Nat Immunol, 25 (8), 1445-1459
DOI 10.1038/s41590-024-01884-z, PubMed 38956379
Health-related quality of life in relapsed/refractory multiple myeloma treated with melflufen and dexamethasone: analyses from the phase III OCEAN study
Haematologica, 109 (7), 2331-2336
DOI 10.3324/haematol.2023.284635, PubMed 38426292
Egr2 to the rescue: nanoparticles revitalize natural killer cells in the fight against cancer
EMBO J, 43 (13), 2527-2529
DOI 10.1038/s44318-024-00144-y, PubMed 38886578
B7-H3: a robust target for immunotherapy in prostate cancer
Trends Cancer, 10 (7), 584-587
DOI 10.1016/j.trecan.2024.05.003, PubMed 38839545
Multiregional transcriptomics identifies congruent consensus subtypes with prognostic value beyond tumor heterogeneity of colorectal cancer
Nat Commun, 15 (1), 4342
DOI 10.1038/s41467-024-48706-2, PubMed 38773143
CD37 is a safe chimeric antigen receptor target to treat acute myeloid leukemia
Cell Rep Med, 5 (6), 101572
DOI 10.1016/j.xcrm.2024.101572, PubMed 38754420
Overall survival and causes of death in elderly patients with Hodgkin lymphoma: a Norwegian population-based case-control study
Haematologica, 109 (5), 1403-1412
DOI 10.3324/haematol.2023.283721, PubMed 37881879
Engineering immune-evasive allogeneic cellular immunotherapies
Nat Rev Immunol, 24 (9), 680-693
DOI 10.1038/s41577-024-01022-8, PubMed 38658708
In multiple myeloma, monthly treatment with zoledronic acid beyond two years offers sustained protection against progressive bone disease
Blood Cancer J, 14 (1), 65
DOI 10.1038/s41408-024-01046-2, PubMed 38622134
Efficient CAR T cell targeting of the CA125 extracellular repeat domain of MUC16
J Immunother Cancer, 12 (4)
DOI 10.1136/jitc-2023-008179, PubMed 38604812
VRD versus VCD as induction therapy before autologous stem cell transplantation in multiple myeloma: a nationwide population-based study
Blood Cancer J, 14 (1), 60
DOI 10.1038/s41408-024-01047-1, PubMed 38594252
Transient TCR-based T cell therapy in a patient with advanced treatment-resistant MSI-high colorectal cancer
Mol Ther, 32 (6), 2021-2029
DOI 10.1016/j.ymthe.2024.04.009, PubMed 38582964
Incidence and Factors Associated With Second Primary Invasive Melanoma in Norway
JAMA Dermatol, 160 (4), 402-408
DOI 10.1001/jamadermatol.2023.6251, PubMed 38416466
Quality of life endpoints in cancer cachexia clinical trials: Systematic review 3 of the cachexia endpoints series
J Cachexia Sarcopenia Muscle, 15 (3), 794-815
DOI 10.1002/jcsm.13453, PubMed 38553255
A dual-purpose fusion complex in autophagy
Cell Res, 34 (3), 183-184
DOI 10.1038/s41422-023-00925-w, PubMed 38228880
Exploring the gut DNA virome in fecal immunochemical test stool samples reveals associations with lifestyle in a large population-based study
Nat Commun, 15 (1), 1791
DOI 10.1038/s41467-024-46033-0, PubMed 38424056
Intercellular transfer of cancer cell invasiveness via endosome-mediated protease shedding
Nat Commun, 15 (1), 1277
DOI 10.1038/s41467-024-45558-8, PubMed 38341434
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature
Biochim Biophys Acta Rev Cancer, 1879 (2), 189080
DOI 10.1016/j.bbcan.2024.189080, PubMed 38272101
Ipilimumab and nivolumab combined with anthracycline-based chemotherapy in metastatic hormone receptor-positive breast cancer: a randomized phase 2b trial
J Immunother Cancer, 12 (1)
DOI 10.1136/jitc-2023-007990, PubMed 38242720
Lysophagy prevents neurotoxic aggregate transmission
Proc Natl Acad Sci U S A, 121 (3), e2321181121
DOI 10.1073/pnas.2321181121, PubMed 38190545
Sudarshan Kriya Yoga Breathing and a Meditation Program for Burnout Among Physicians: A Randomized Clinical Trial
JAMA Netw Open, 7 (1), e2353978
DOI 10.1001/jamanetworkopen.2023.53978, PubMed 38294813
ATPase-regulated autophagosome biogenesis
Autophagy, 20 (1), 218-219
DOI 10.1080/15548627.2023.2255967, PubMed 37722386
Robust scoring of selective drug responses for patient-tailored therapy selection
Nat Protoc, 19 (1), 60-82
DOI 10.1038/s41596-023-00903-x, PubMed 37996540
Removal of hypersignaling endosomes by simaphagy
Autophagy, 20 (4), 769-791
DOI 10.1080/15548627.2023.2267958, PubMed 37840274
Adipose-Derived Stromal Cells Preserve Pancreatic Islet Function in a Transplantable 3D Bioprinted Scaffold
Adv Healthc Mater, 12 (32), e2300640
DOI 10.1002/adhm.202300640, PubMed 37781993
Transcriptomic subtyping of malignant peripheral nerve sheath tumours highlights immune signatures, genomic profiles, patient survival and therapeutic targets
EBioMedicine, 97, 104829
DOI 10.1016/j.ebiom.2023.104829, PubMed 37837931
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo
Nat Cancer, 4 (10), 1474-1490
DOI 10.1038/s43018-023-00642-8, PubMed 37783807
Mapping the chemotactic landscape in NK cells reveals subset-specific synergistic migratory responses to dual chemokine receptor ligation
EBioMedicine, 96, 104811
DOI 10.1016/j.ebiom.2023.104811, PubMed 37741009
Adverse health outcomes and global quality of life in long-term testicular cancer survivors: a longitudinal 30-year perspective
Ann Oncol, 34 (12), 1165-1174
DOI 10.1016/j.annonc.2023.09.3101, PubMed 37739265
The separate axes of TECPR1 and ATG16L1 in CASM
Autophagy, 20 (1), 214-215
DOI 10.1080/15548627.2023.2255462, PubMed 37676042
The Geriatric Prognostic Index: a clinical prediction model for survival of older diffuse large B-cell lymphoma patients treated with standard immunochemotherapy
Haematologica, 108 (9), 2454-2466
DOI 10.3324/haematol.2022.282289, PubMed 36861406
Clinical Activity of Combined Telomerase Vaccination and Pembrolizumab in Advanced Melanoma: Results from a Phase I Trial
Clin Cancer Res, 29 (16), 3026-3036
DOI 10.1158/1078-0432.CCR-23-0416, PubMed 37378632
Intensifying treatment in PET-positive multiple myeloma patients after upfront autologous stem cell transplantation
Leukemia, 37 (10), 2107-2114
DOI 10.1038/s41375-023-01998-7, PubMed 37568010
A phosphoinositide kinase triggers migrasome formation
Cell Res, 33 (8), 577-578
DOI 10.1038/s41422-023-00822-2, PubMed 37165066
WT1 and PRAME RNA-loaded dendritic cell vaccine as maintenance therapy in de novo AML after intensive induction chemotherapy
Leukemia, 37 (9), 1842-1849
DOI 10.1038/s41375-023-01980-3, PubMed 37507426
ATPase activity of DFCP1 controls selective autophagy
Nat Commun, 14 (1), 4051
DOI 10.1038/s41467-023-39641-9, PubMed 37422481
TECPR1 is activated by damage-induced sphingomyelin exposure to mediate noncanonical autophagy
EMBO J, 42 (17), e113105
DOI 10.15252/embj.2022113105, PubMed 37409525
ALPL-1 is a target for chimeric antigen receptor therapy in osteosarcoma
Nat Commun, 14 (1), 3375
DOI 10.1038/s41467-023-39097-x, PubMed 37291203
Improved survival in myeloma patients-a nationwide registry study of 4,647 patients ≥75 years treated in Denmark and Sweden
Haematologica, 108 (6), 1640-1651
DOI 10.3324/haematol.2021.280424, PubMed 36300775
The Effects of Exercise Training in Patients With Persistent Dyspnea Following Pulmonary Embolism: A Randomized Controlled Trial
Chest, 164 (4), 981-991
DOI 10.1016/j.chest.2023.04.042, PubMed 37149257
Reply to the Letter to the Editor "A simple way of doing the complex but utmost important things: cancer pain management" by S. Singhal, M. Verma and D. Kukreja
Ann Oncol, 34 (5), 496-497
DOI 10.1016/j.annonc.2023.02.005, PubMed 37121609
Mortality by age, gene and gender in carriers of pathogenic mismatch repair gene variants receiving surveillance for early cancer diagnosis and treatment: a report from the prospective Lynch syndrome database
EClinicalMedicine, 58, 101909
DOI 10.1016/j.eclinm.2023.101909, PubMed 37181409
Human small intestine contains 2 functionally distinct regulatory T-cell subsets
J Allergy Clin Immunol, 152 (1), 278-289.e6
DOI 10.1016/j.jaci.2023.02.030, PubMed 36893861
Author Correction: Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution
Nat Commun, 14 (1), 648
DOI 10.1038/s41467-023-36404-4, PubMed 36746973
Clathrin mediates both internalization and vesicular release of triggered T cell receptor at the immunological synapse
Proc Natl Acad Sci U S A, 120 (6), e2211368120
DOI 10.1073/pnas.2211368120, PubMed 36730202
PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
Haematologica, 108 (1), 9-21
DOI 10.3324/haematol.2022.281266, PubMed 35899388
T cell receptor repertoire sequencing reveals chemotherapy-driven clonal expansion in colorectal liver metastases
Gigascience, 12
DOI 10.1093/gigascience/giad032, PubMed 37161965
Targeted Therapy on the Screen: Do We Hit the Target?
Clin Cancer Res, 28 (24), 5233-5234
DOI 10.1158/1078-0432.CCR-22-2707, PubMed 36240006
Regulation of autophagosome biogenesis and mitochondrial bioenergetics by the cholesterol transport protein GRAMD1C
Autophagy, 19 (7), 2159-2161
DOI 10.1080/15548627.2022.2155020, PubMed 36469687
Atezolizumab plus anthracycline-based chemotherapy in metastatic triple-negative breast cancer: the randomized, double-blind phase 2b ALICE trial
Nat Med, 28 (12), 2573-2583
DOI 10.1038/s41591-022-02126-1, PubMed 36482103
Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
Eur Urol, 83 (2), 183
DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529
Cis-regulatory mutations associate with transcriptional and post-transcriptional deregulation of gene regulatory programs in cancers
Nucleic Acids Res, 50 (21), 12131-12148
DOI 10.1093/nar/gkac1143, PubMed 36477895
Cholesterol transfer via endoplasmic reticulum contacts mediates lysosome damage repair
EMBO J, 41 (24), e112677
DOI 10.15252/embj.2022112677, PubMed 36408828
Total late effect burden in long-term lymphoma survivors after high-dose therapy with autologous stem-cell transplant and its effect on health-related quality of life
Haematologica, 107 (11), 2698-2707
DOI 10.3324/haematol.2021.280413, PubMed 35484681
The cholesterol transport protein GRAMD1C regulates autophagy initiation and mitochondrial bioenergetics
Nat Commun, 13 (1), 6283
DOI 10.1038/s41467-022-33933-2, PubMed 36270994
Functional Testing to Characterize and Stratify PI3K Inhibitor Responses in Chronic Lymphocytic Leukemia
Clin Cancer Res, 28 (20), 4444-4455
DOI 10.1158/1078-0432.CCR-22-1221, PubMed 35998013
Estimated daily intake of phthalates, parabens, and bisphenol A in hospitalised very low birth weight infants
Chemosphere, 309 (Pt 1), 136687
DOI 10.1016/j.chemosphere.2022.136687, PubMed 36206919
Functional precision cancer medicine: drug sensitivity screening enabled by cell culture models
Trends Pharmacol Sci, 43 (11), 973-985
DOI 10.1016/j.tips.2022.08.009, PubMed 36163057
A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV
Nucleic Acids Res, 50 (15), e89
DOI 10.1093/nar/gkac434, PubMed 35641102
Determining drug dose in the era of targeted therapies: playing it (un)safe?
Blood Cancer J, 12 (8), 123
DOI 10.1038/s41408-022-00720-7, PubMed 35999205
A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a development and validation study
Lancet Oncol, 23 (9), 1221-1232
DOI 10.1016/S1470-2045(22)00391-6, PubMed 35964620
An immunity and pyroptosis gene-pair signature predicts overall survival in acute myeloid leukemia
Leukemia, 36 (10), 2384-2395
DOI 10.1038/s41375-022-01662-6, PubMed 35945345
Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
Haematologica, 107 (8), 1994-1998
DOI 10.3324/haematol.2021.280393, PubMed 35236056
An Experimental Generator for Production of High-Purity 212Pb for Use in Radiopharmaceuticals
J Nucl Med, 64 (1), 173-176
DOI 10.2967/jnumed.122.264009, PubMed 35798556
ESCRTed resistance to T cell attack
Trends Immunol, 43 (8), 598-600
DOI 10.1016/j.it.2022.06.007, PubMed 35810056
SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples
Nucleic Acids Res, 50 (W1), W739-W743
DOI 10.1093/nar/gkac382, PubMed 35580060