Divison of Cancer Medicine Last 100 publications from major journals with first or last author from OUS
Is venous thromboembolism a problem in patients with cancer in palliative care?
Lancet Haematol, 6 (2), e61-e62
DOI 10.1016/S2352-3026(18)30218-7, PubMed 30709433
Remodeling of secretory lysosomes during education tunes functional potential in NK cells
Nat Commun, 10 (1), 514
DOI 10.1038/s41467-019-08384-x, PubMed 30705279
Combination therapies with HSP90 inhibitors against colorectal cancer
Biochim Biophys Acta Rev Cancer, 1871 (2), 240-247 (in press)
DOI 10.1016/j.bbcan.2019.01.002, PubMed 30708039
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
Nat Commun, 10 (1), 525
DOI 10.1038/s41467-019-08512-7, PubMed 30692535
IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Nat Commun, 10 (1), 323
DOI 10.1038/s41467-018-08152-3, PubMed 30679434
TIGIT and PD-1 mark intratumoral T cells with reduced effector function in B-cell non-Hodgkin lymphoma
Cancer Immunol Res (in press)
DOI 10.1158/2326-6066.CIR-18-0351, PubMed 30659053
Author Correction: Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
Nat Commun, 9 (1), 5397
DOI 10.1038/s41467-018-07842-2, PubMed 30559362
Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 11698-11711
DOI 10.1093/nar/gky846, PubMed 30247619
Cdk1 gates cell cycle-dependent tRNA synthesis by regulating RNA polymerase III activity
Nucleic Acids Res, 46 (22), 12188-12189
DOI 10.1093/nar/gky1102, PubMed 30395271
Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1
Nucleic Acids Res (in press)
DOI 10.1093/nar/gky1233, PubMed 30541148
A map of direct TF-DNA interactions in the human genome
Nucleic Acids Res (in press)
DOI 10.1093/nar/gky1210, PubMed 30517703
Orchestrating Nuclear Envelope Sealing during Mitosis
Dev Cell, 47 (5), 541-542
DOI 10.1016/j.devcel.2018.11.020, PubMed 30513298
Association Between Proportion of Nuclei With High Chromatin Entropy and Prognosis in Gynecological Cancers
J Natl Cancer Inst, 110 (12), 1400-1408
DOI 10.1093/jnci/djy063, PubMed 29684152
Time series analysis of neoadjuvant chemotherapy and bevacizumab-treated breast carcinomas reveals a systemic shift in genomic aberrations
Genome Med, 10 (1), 92
DOI 10.1186/s13073-018-0601-y, PubMed 30497530
Integration of oncology and palliative care: a Lancet Oncology Commission
Lancet Oncol, 19 (11), e588-e653
DOI 10.1016/S1470-2045(18)30415-7, PubMed 30344075
ESCRT-mediated lysosome repair precedes lysophagy and promotes cell survival
EMBO J, 37 (21)
DOI 10.15252/embj.201899753, PubMed 30314966
Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity
Eur Urol, 75 (3), 498-505
DOI 10.1016/j.eururo.2018.08.009, PubMed 30181068
Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation
Nat Commun, 9 (1), 2932
DOI 10.1038/s41467-018-05345-8, PubMed 30050131
Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients
Cancer Res, 78 (16), 4774-4785
DOI 10.1158/0008-5472.CAN-17-3806, PubMed 29945958
Reply
Gastroenterology, 155 (1), 228
DOI 10.1053/j.gastro.2018.06.032, PubMed 29894682
Centrosomal ALIX regulates mitotic spindle orientation by modulating astral microtubule dynamics
EMBO J, 37 (13)
DOI 10.15252/embj.201797741, PubMed 29858227
K27/G34 versus K28/G35 in histone H3-mutant gliomas: A note of caution
Acta Neuropathol, 136 (1), 175-176
DOI 10.1007/s00401-018-1867-2, PubMed 29766298
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells
Haematologica (in press)
DOI 10.3324/haematol.2018.189399, PubMed 29748445
CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer
Ann Oncol, 29 (5), 1227-1234
DOI 10.1093/annonc/mdy085, PubMed 29518181
Put science first and formatting later
EMBO Rep, 19 (5)
DOI 10.15252/embr.201845731, PubMed 29650529
Complex Polygenic Nature of Testicular Germ Cell Cancer Suggests Multifactorial Aetiology
Eur Urol, 73 (6), 832-833
DOI 10.1016/j.eururo.2018.02.023, PubMed 29530636
Prognostic markers for colorectal cancer: estimating ploidy and stroma
Ann Oncol, 29 (3), 616-623
DOI 10.1093/annonc/mdx794, PubMed 29293881
Intrinsic Functional Potential of NK-Cell Subsets Constrains Retargeting Driven by Chimeric Antigen Receptors
Cancer Immunol Res, 6 (4), 467-480
DOI 10.1158/2326-6066.CIR-17-0207, PubMed 29459477
Complete Remission with Reduction of High-Risk Clones following Haploidentical NK-Cell Therapy against MDS and AML
Clin Cancer Res, 24 (8), 1834-1844
DOI 10.1158/1078-0432.CCR-17-3196, PubMed 29444931
Chromatin organisation and cancer prognosis: a pan-cancer study
Lancet Oncol, 19 (3), 356-369
DOI 10.1016/S1470-2045(17)30899-9, PubMed 29402700
Early integration of palliative care-new evidence and old questions
Lancet Oncol, 19 (3), 280-281
DOI 10.1016/S1470-2045(18)30061-5, PubMed 29402702
Ibrutinib, lenalidomide, and rituximab in relapsed or refractory mantle cell lymphoma (PHILEMON): a multicentre, open-label, single-arm, phase 2 trial
Lancet Haematol, 5 (3), e109-e116
DOI 10.1016/S2352-3026(18)30018-8, PubMed 29396091
Plasminogen replacement therapy for the treatment of children and adults with congenital plasminogen deficiency
Blood, 131 (12), 1301-1310
DOI 10.1182/blood-2017-09-806729, PubMed 29321155
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
Nucleic Acids Res, 46 (D1), D1284
DOI 10.1093/nar/gkx1188, PubMed 29161433
JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework
Nucleic Acids Res, 46 (D1), D260-D266
DOI 10.1093/nar/gkx1126, PubMed 29140473
Epigenetic biomarkers in gastrointestinal cancers: The current state and clinical perspectives
Semin Cancer Biol, 51, 36-49
DOI 10.1016/j.semcancer.2017.12.004, PubMed 29253542
Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies
Clin Cancer Res, 24 (4), 794-806
DOI 10.1158/1078-0432.CCR-17-1234, PubMed 29242316
T Cells Expressing Checkpoint Receptor TIGIT Are Enriched in Follicular Lymphoma Tumors and Characterized by Reversible Suppression of T-cell Receptor Signaling
Clin Cancer Res, 24 (4), 870-881
DOI 10.1158/1078-0432.CCR-17-2337, PubMed 29217528
A Positively Charged Surface Triggers Coagulation Activation Through Factor VII Activating Protease (FSAP)
ACS Appl Mater Interfaces, 9 (46), 40107-40116
DOI 10.1021/acsami.7b14281, PubMed 29091393
DNA methylation at enhancers identifies distinct breast cancer lineages
Nat Commun, 8 (1), 1379
DOI 10.1038/s41467-017-00510-x, PubMed 29123100
Fructan, Rather Than Gluten, Induces Symptoms in Patients With Self-Reported Non-Celiac Gluten Sensitivity
Gastroenterology, 154 (3), 529-539.e2
DOI 10.1053/j.gastro.2017.10.040, PubMed 29102613
Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors
Nat Commun, 8 (1), 1221
DOI 10.1038/s41467-017-01355-0, PubMed 29089486
Class III phosphatidylinositol-3-OH kinase controls epithelial integrity through endosomal LKB1 regulation
Nat Cell Biol, 19 (12), 1412-1423
DOI 10.1038/ncb3631, PubMed 29084199
PtdIns3P controls mTORC1 signaling through lysosomal positioning
J Cell Biol, 216 (12), 4217-4233
DOI 10.1083/jcb.201611073, PubMed 29030394
Acute liver graft rejection after ipilimumab therapy
Ann Oncol, 28 (10), 2619-2620
DOI 10.1093/annonc/mdx281, PubMed 28961840
Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
Gut, 67 (7), 1306-1316
DOI 10.1136/gutjnl-2017-314057, PubMed 28754778
Microenvironment and tumors-a nurturing relationship
Autophagy, 13 (7), 1241-1243
DOI 10.1080/15548627.2017.1310361, PubMed 28632995
Ex Vivo Expanded Adaptive NK Cells Effectively Kill Primary Acute Lymphoblastic Leukemia Cells
Cancer Immunol Res, 5 (8), 654-665
DOI 10.1158/2326-6066.CIR-16-0296, PubMed 28637877
SeqA structures behind Escherichia coli replication forks affect replication elongation and restart mechanisms
Nucleic Acids Res, 45 (11), 6471-6485
DOI 10.1093/nar/gkx263, PubMed 28407100
Suppressing mTORC1 on the lysosome
EMBO J, 36 (13), 1809-1810
DOI 10.15252/embj.201797469, PubMed 28623241
Manufacture of CAR-T cells in the body
Nat Biotechnol, 35 (6), 520-521
DOI 10.1038/nbt.3898, PubMed 28591119
Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer
Cell Rep, 19 (10), 2045-2059
DOI 10.1016/j.celrep.2017.05.049, PubMed 28591577
Multilevel genomics of colorectal cancers with microsatellite instability-clinical impact of JAK1 mutations and consensus molecular subtype 1
Genome Med, 9 (1), 46
DOI 10.1186/s13073-017-0434-0, PubMed 28539123
Bendamustine plus rituximab for chronic cold agglutinin disease: results of a Nordic prospective multicenter trial
Blood, 130 (4), 537-541
DOI 10.1182/blood-2017-04-778175, PubMed 28533306
Muscle mass and association to quality of life in non-small cell lung cancer patients
J Cachexia Sarcopenia Muscle, 8 (5), 759-767
DOI 10.1002/jcsm.12206, PubMed 28493418
The Longitudinal Transcriptional Response to Neoadjuvant Chemotherapy with and without Bevacizumab in Breast Cancer
Clin Cancer Res, 23 (16), 4662-4670
DOI 10.1158/1078-0432.CCR-17-0160, PubMed 28487444
Chemotherapy in end-of-life care
Ann Oncol, 28 (4), 684-685
DOI 10.1093/annonc/mdx039, PubMed 28327919
Lipids in exosomes: Current knowledge and the way forward
Prog Lipid Res, 66, 30-41
DOI 10.1016/j.plipres.2017.03.001, PubMed 28342835
Genetics of primary sclerosing cholangitis and pathophysiological implications
Nat Rev Gastroenterol Hepatol, 14 (5), 279-295
DOI 10.1038/nrgastro.2016.154, PubMed 28293027
An Evolutionarily Conserved Role for Polydom/Svep1 During Lymphatic Vessel Formation
Circ Res, 120 (8), 1263-1275
DOI 10.1161/CIRCRESAHA.116.308813, PubMed 28179432
Doping and drug testing: Anti-doping work must be transparent and adhere to good scientific practices to ensure public trust
EMBO Rep, 18 (3), 351-354
DOI 10.15252/embr.201643540, PubMed 28167676
The Antigenicity of the Tumor Cell - Context Matters
N Engl J Med, 376 (5), 491-493
DOI 10.1056/NEJMcibr1613793, PubMed 28146670
TORC1-dependent sumoylation of Rpc82 promotes RNA polymerase III assembly and activity
Proc Natl Acad Sci U S A, 114 (5), 1039-1044
DOI 10.1073/pnas.1615093114, PubMed 28096404
Microenvironmental autophagy promotes tumour growth
Nature, 541 (7637), 417-420
DOI 10.1038/nature20815, PubMed 28077876
Injection of nanoparticles into cloven-hoof animals: Asking for trouble
Theranostics, 7 (19), 4877-4878
DOI 10.7150/thno.22420, PubMed 29187910
Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing
Genome Biol, 17 (1), 250
DOI 10.1186/s13059-016-1109-7, PubMed 27931250
The Abscission Checkpoint: Making It to the Final Cut
Trends Cell Biol, 27 (1), 1-11
DOI 10.1016/j.tcb.2016.10.001, PubMed 27810282
Reply to O. Corli et al and M. Lucchesi et al
J Clin Oncol, 34 (29), 3581-3582
DOI 10.1200/JCO.2016.67.7534, PubMed 27458292
Cellular Functions and Molecular Mechanisms of the ESCRT Membrane-Scission Machinery
Trends Biochem Sci, 42 (1), 42-56
DOI 10.1016/j.tibs.2016.08.016, PubMed 27669649
CTCF modulates Estrogen Receptor function through specific chromatin and nuclear matrix interactions
Nucleic Acids Res, 44 (22), 10588-10602
DOI 10.1093/nar/gkw785, PubMed 27638884
The role of opioids in cancer progression: emerging experimental and clinical implications
Ann Oncol, 27 (11), 1978-1980
DOI 10.1093/annonc/mdw407, PubMed 27573559
DNA Shape Features Improve Transcription Factor Binding Site Predictions In Vivo
Cell Syst, 3 (3), 278-286.e4
DOI 10.1016/j.cels.2016.07.001, PubMed 27546793
Phosphoinositides in Control of Membrane Dynamics
Annu Rev Cell Dev Biol, 32, 143-171
DOI 10.1146/annurev-cellbio-111315-125349, PubMed 27576122
The Genomic Landscape of Pancreatic and Periampullary Adenocarcinoma
Cancer Res, 76 (17), 5092-102
DOI 10.1158/0008-5472.CAN-16-0658, PubMed 27488532
Gene Expression Architecture of Mouse Dorsal and Tail Skin Reveals Functional Differences in Inflammation and Cancer
Cell Rep, 16 (4), 1153-1165
DOI 10.1016/j.celrep.2016.06.061, PubMed 27425619
Poor concordance between CA-125 and RECIST at the time of disease progression in patients with platinum-resistant ovarian cancer: analysis of the AURELIA trial
Ann Oncol, 27 (8), 1505-10
DOI 10.1093/annonc/mdw238, PubMed 27407100
Molecular Features of Subtype-Specific Progression from Ductal Carcinoma In Situ to Invasive Breast Cancer
Cell Rep, 16 (4), 1166-1179
DOI 10.1016/j.celrep.2016.06.051, PubMed 27396337
Plasma membrane repairs by small GTPase Rab3a
J Cell Biol, 213 (6), 613-5
DOI 10.1083/jcb.201606006, PubMed 27325788
Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
Gut, 66 (9), 1657-1664
DOI 10.1136/gutjnl-2016-311403, PubMed 27261338
Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
Science, 352 (6291), 1337-41
DOI 10.1126/science.aaf2288, PubMed 27198675
Novel ESCRT functions in cell biology: spiraling out of control?
Curr Opin Cell Biol, 41, 1-8
DOI 10.1016/j.ceb.2016.03.008, PubMed 27031044
The Impact of Gene Expression Patterns in Breast Cancer
Clin Chem, 62 (8), 1150-1
DOI 10.1373/clinchem.2015.253229, PubMed 27022070
Ten- and 15-yr Prostate Cancer-specific Mortality in Patients with Nonmetastatic Locally Advanced or Aggressive Intermediate Prostate Cancer, Randomized to Lifelong Endocrine Treatment Alone or Combined with Radiotherapy: Final Results of The Scandinavian Prostate Cancer Group-7
Eur Urol, 70 (4), 684-691
DOI 10.1016/j.eururo.2016.03.021, PubMed 27025586
Closing a gap in the nuclear envelope
Curr Opin Cell Biol, 40, 90-97
DOI 10.1016/j.ceb.2016.03.001, PubMed 27016712
Integrative Analysis of DCE-MRI and Gene Expression Profiles in Construction of a Gene Classifier for Assessment of Hypoxia-Related Risk of Chemoradiotherapy Failure in Cervical Cancer
Clin Cancer Res, 22 (16), 4067-76
DOI 10.1158/1078-0432.CCR-15-2322, PubMed 27012812
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
J Cell Biol, 212 (5), 499-513
DOI 10.1083/jcb.201507009, PubMed 26929449
Post-thrombotic syndrome after catheter-directed thrombolysis for deep vein thrombosis (CaVenT): 5-year follow-up results of an open-label, randomised controlled trial
Lancet Haematol, 3 (2), e64-71
DOI 10.1016/S2352-3026(15)00248-3, PubMed 26853645
Identification of Novel Fusion Genes in Testicular Germ Cell Tumors
Cancer Res, 76 (1), 108-16
DOI 10.1158/0008-5472.CAN-15-1790, PubMed 26659575
Revisiting tumour aneuploidy - the place of ploidy assessment in the molecular era
Nat Rev Clin Oncol, 13 (5), 291-304
DOI 10.1038/nrclinonc.2015.208, PubMed 26598944
Maintaining a Healthy Balance: Targeting TERT to Stem Benign Prostatic Hyperplasia
Eur Urol, 69 (4), 555-556
DOI 10.1016/j.eururo.2015.10.028, PubMed 26520704
From autonomy to community; new perspectives on tumorigenicity and therapy resistance
Cancer Treat Rev, 41 (10), 809-13
DOI 10.1016/j.ctrv.2015.10.004, PubMed 26519005
Newtonian cell interactions shape natural killer cell education
Immunol Rev, 267 (1), 197-213
DOI 10.1111/imr.12325, PubMed 26284479
Chronic fatigue in 812 testicular cancer survivors during long-term follow-up: increasing prevalence and risk factors
Ann Oncol, 26 (10), 2133-40
DOI 10.1093/annonc/mdv328, PubMed 26265167
Simultaneous measurement of passage through the restriction point and MCM loading in single cells
Nucleic Acids Res, 43 (22), e150
DOI 10.1093/nar/gkv744, PubMed 26250117
Heart Failure and Asymptomatic Left Ventricular Systolic Dysfunction in Lymphoma Survivors Treated With Autologous Stem-Cell Transplantation: A National Cross-Sectional Study
J Clin Oncol, 33 (24), 2683-91
DOI 10.1200/JCO.2015.60.8125, PubMed 26169610
A Novel Concept for Partial Liver Transplantation in Nonresectable Colorectal Liver Metastases: The RAPID Concept
Ann Surg, 262 (1), e5-9
DOI 10.1097/SLA.0000000000001165, PubMed 25692361
Spastin and ESCRT-III coordinate mitotic spindle disassembly and nuclear envelope sealing
Nature, 522 (7555), 231-5
DOI 10.1038/nature14408, PubMed 26040712
ER-endosome contact sites: molecular compositions and functions
EMBO J, 34 (14), 1848-58
DOI 10.15252/embj.201591481, PubMed 26041457
Divergent androgen regulation of unfolded protein response pathways drives prostate cancer
EMBO Mol Med, 7 (6), 788-801
DOI 10.15252/emmm.201404509, PubMed 25864123
Molecular subtyping of prostate cancer: a partnership model
Eur Urol, 68 (4), 568-9
DOI 10.1016/j.eururo.2015.05.012, PubMed 26001612