Divison of Cancer Medicine Last 100 publications from major journals with first or last author from OUS

Kleppe A, Skrede OJ, De Raedt S, Hveem TS, Askautrud HA, Jacobsen JE, Church DN, Nesbakken A, Shepherd NA, Novelli M, Kerr R, Liestøl K, Kerr DJ, Danielsen HE (2022)
A clinical decision support system optimising adjuvant chemotherapy for colorectal cancers by integrating deep learning and pathological staging markers: a development and validation study
Lancet Oncol (in press)
DOI 10.1016/S1470-2045(22)00391-6, PubMed 35964620

Kong W, He L, Zhu J, Brück O, Porkka K, Heckman CA, Zhu S, Aittokallio T (2022)
An immunity and pyroptosis gene-pair signature predicts overall survival in acute myeloid leukemia
Leukemia (in press)
DOI 10.1038/s41375-022-01662-6, PubMed 35945345

Skånland SS, Inngjerdingen M, Bendiksen H, York J, Spetalen S, Munthe LA, Tjønnfjord GE (2022)
Functional testing of relapsed chronic lymphocytic leukemia guides precision medicine and maps response and resistance mechanisms. An index case
Haematologica, 107 (8), 1994-1998
DOI 10.3324/haematol.2021.280393, PubMed 35236056

Skanland SS, Brown JR (2022)
PI3K inhibitors in chronic lymphocytic leukemia: where do we go from here?
Haematologica (in press)
DOI 10.3324/haematol.2022.281266, PubMed 35899388

Migliano SM, Stenmark H (2022)
ESCRTed resistance to T cell attack
Trends Immunol, 43 (8), 598-600
DOI 10.1016/j.it.2022.06.007, PubMed 35810056

Fusser M, Øverbye A, Pandya AD, Mørch Ý, Borgos SE, Kildal W, Snipstad S, Sulheim E, Fleten KG, Askautrud HA, Engebraaten O, Flatmark K, Iversen TG, Sandvig K, Skotland T, Mælandsmo GM (2022)
Corrigendum to "Cabazitaxel-loaded Poly(2-ethylbutyl cyanoacrylate) nanoparticles improve treatment efficacy in a patient derived breast cancer xenograft", [Journal of Control Release, 293 (2019) 183-192]
J Control Release, 349, 1 (in press)
DOI 10.1016/j.jconrel.2022.06.040, PubMed 35792388

Bay LTE, Syljuåsen RG, Landsverk HB (2022)
A novel, rapid and sensitive flow cytometry method reveals degradation of promoter proximal paused RNAPII in the presence and absence of UV
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkac434, PubMed 35641102

Ianevski A, Giri AK, Aittokallio T (2022)
SynergyFinder 3.0: an interactive analysis and consensus interpretation of multi-drug synergies across multiple samples
Nucleic Acids Res (in press)
DOI 10.1093/nar/gkac382, PubMed 35580060

Skotland T, Iversen TG, Llorente A, Sandvig K (2022)
Biodistribution, pharmacokinetics and excretion studies of intravenously injected nanoparticles and extracellular vesicles: Possibilities and challenges
Adv Drug Deliv Rev, 186, 114326
DOI 10.1016/j.addr.2022.114326, PubMed 35588953

Khezri R, Rusten TE (2022)
Autophagy power expands: fuse those cells!
EMBO J, 41 (12), e111424
DOI 10.15252/embj.2022111424, PubMed 35561082

Horn MA, Myhre AE, Prescott T, Aasly J, Sundal CH, Gedde-Dahl T (2022)
Prophylactic Allogeneic Hematopoietic Stem Cell Therapy for CSF1R-Related Leukoencephalopathy
Mov Disord, 37 (5), 1108-1109
DOI 10.1002/mds.29011, PubMed 35587623

Ellingsen EB, Aamdal E, Guren T, Lilleby W, Brunsvig PF, Mangsbo SM, Aamdal S, Hovig E, Mensali N, Gaudernack G, Inderberg EM (2022)
Durable and dynamic hTERT immune responses following vaccination with the long-peptide cancer vaccine UV1: long-term follow-up of three phase I clinical trials
J Immunother Cancer, 10 (5)
DOI 10.1136/jitc-2021-004345, PubMed 35613827

Taskén K, Russnes HEG, Aas E, Bjørge L, Blix ES, CONNECT Public–Private Partnership Consortium, Enerly E, Fagereng GL, Flobak Å, Gilje B, Gjertsen BT, Guren TK, Heix J, Hovig E, Hovland R, InPreD-Norway and National Molecular Tumor Board Consortium, IMPRESS-Norway Consortium, Lønning PE, Meza-Zepeda LA, Mæhle PM, Nilsen HL, Thoresen SØ, Widerberg K, Smeland S, Helland Å (2022)
A national precision cancer medicine implementation initiative for Norway
Nat Med, 28 (5), 885-887
DOI 10.1038/s41591-022-01777-4, PubMed 35513529

Smeland K, Holte H, Fagerli UM, Bersvendsen H, Hjermstad MJ, Loge JH, Murbrach K, Linnsund MD, Fluge O, Stenehjem JS, Lund MB, Kvaloy S, Kiserud CE (2022)
Total late effect burden in long-term lymphoma survivors after highdose therapy with autologous stem-cell transplant and its effect on health-related quality of life
Haematologica (in press)
DOI 10.3324/haematol.2021.280413, PubMed 35484681

Fosså SD, Dahl AA, Thorsen L, Hellesnes R, Kiserud CE, Tandstad T, Brydøy M, Haugnes HS, Myklebust TÅ (2022)
Mortality and Second Cancer Incidence After Treatment for Testicular Cancer: Psychosocial Health and Lifestyle Are Modifiable Prognostic Factors
J Clin Oncol, 40 (23), 2588-2599
DOI 10.1200/JCO.21.02105, PubMed 35380874

Schjesvold FH, Bakker NA, Sonneveld P (2022)
Melflufen in multiple myeloma: the conclusion matters - Authors' reply
Lancet Haematol, 9 (4), e244-e245
DOI 10.1016/S2352-3026(22)00071-0, PubMed 35358436

Skotland T, Sandvig K (2022)
Need for more focus on lipid species in studies of biological and model membranes
Prog Lipid Res, 86, 101160
DOI 10.1016/j.plipres.2022.101160, PubMed 35288150

Ianevski A, Giri AK, Aittokallio T (2022)
Fully-automated and ultra-fast cell-type identification using specific marker combinations from single-cell transcriptomic data
Nat Commun, 13 (1), 1246
DOI 10.1038/s41467-022-28803-w, PubMed 35273156

Migliano SM, Wenzel EM, Stenmark H (2022)
Biophysical and molecular mechanisms of ESCRT functions, and their implications for disease
Curr Opin Cell Biol, 75, 102062
DOI 10.1016/j.ceb.2022.01.007, PubMed 35248976

Schjesvold F, Richardson PG, Facon T, Alegre A, Spencer A, Jurczyszyn A, Sunami K, Frenzel L, Min CK, Guillonneau S, Lin PL, Le-Guennec S, Campana F, Van de Velde H, Bensfia S, Bringhen S (2022)
Isatuximab plus pomalidomide and dexamethasone in elderly patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis
Haematologica, 107 (3), 774-775
DOI 10.3324/haematol.2021.279160, PubMed 35229573

Simonsen A, Wollert T (2022)
Don't forget to be picky - selective autophagy of protein aggregates in neurodegenerative diseases
Curr Opin Cell Biol, 75, 102064
DOI 10.1016/j.ceb.2022.01.009, PubMed 35240373

Dominguez-Valentin M, Sampson JR, Seppälä TT, Møller P (2022)
Response to Chambuso et al
Genet Med, 24 (5), 1151
DOI 10.1016/j.gim.2022.01.005, PubMed 35216900

Hammer Q, Dunst J, Christ W, Picarazzi F, Wendorff M, Momayyezi P, Huhn O, Netskar HK, Maleki KT, García M, Sekine T, Sohlberg E, Azzimato V, Aouadi M, Karolinska COVID-19 Study Group, Severe COVID-19 GWAS Group, Degenhardt F, Franke A, Spallotta F, Mori M, Michaëlsson J, Björkström NK, Rückert T, Romagnani C, Horowitz A et al. (2022)
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Cell Rep, 38 (10), 110503
DOI 10.1016/j.celrep.2022.110503, PubMed 35235832

Nissen-Meyer J, Skotland T, Boye E (2022)
Are doping tests in sports trustworthy?: Athletes suffer from insufficiently defined criteria for doping tests: Athletes suffer from insufficiently defined criteria for doping tests
EMBO Rep, 23 (3), e54431
DOI 10.15252/embr.202154431, PubMed 35156749

Ballester PJ, Stevens R, Haibe-Kains B, Huang RS, Aittokallio T (2022)
Artificial intelligence for drug response prediction in disease models
Brief Bioinform, 23 (1)
DOI 10.1093/bib/bbab450, PubMed 34655289

Schjesvold FH, Dimopoulos MA, Delimpasi S, Robak P, Coriu D, Legiec W, Pour L, Špička I, Masszi T, Doronin V, Minarik J, Salogub G, Alekseeva Y, Lazzaro A, Maisnar V, Mikala G, Rosiñol L, Liberati AM, Symeonidis A, Moody V, Thuresson M, Byrne C, Harmenberg J, Bakker NA, Hájek R et al. (2022)
Melflufen or pomalidomide plus dexamethasone for patients with multiple myeloma refractory to lenalidomide (OCEAN): a randomised, head-to-head, open-label, phase 3 study
Lancet Haematol, 9 (2), e98-e110
DOI 10.1016/S2352-3026(21)00381-1, PubMed 35032434

Skotheim RI, Axcrona U, Axcrona K (2022)
Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
Eur Urol, 81 (4), 431
DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159

Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Simonsen A (2022)
GAK and PRKCD kinases regulate basal mitophagy
Autophagy, 18 (2), 467-469
DOI 10.1080/15548627.2021.2015154, PubMed 35001811

Sivanesan S, Taskén KA, Grytli HH (2022)
Association of β-Blocker Use at Time of Radical Prostatectomy With Rate of Treatment for Prostate Cancer Recurrence
JAMA Netw Open, 5 (1), e2145230
DOI 10.1001/jamanetworkopen.2021.45230, PubMed 35080602

Kryeziu K, Bergsland CH, Guren TK, Sveen A, Lothe RA (2022)
Multiplex immunohistochemistry of metastatic colorectal cancer and ex vivo tumor avatars
Biochim Biophys Acta Rev Cancer, 1877 (1), 188682
DOI 10.1016/j.bbcan.2022.188682, PubMed 35065193

Garcia I, Orellana-Muñoz S, Ramos-Alonso L, Andersen AN, Zimmermann C, Eriksson J, Bøe SO, Kaferle P, Papamichos-Chronakis M, Chymkowitch P, Enserink JM (2021)
Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
Cell Rep, 37 (13), 110186
DOI 10.1016/j.celrep.2021.110186, PubMed 34965431

Sharma K, Asp NT, Harrison S, Siller R, Baumgarten SF, Gupta S, Chollet ME, Andersen E, Sullivan GJ, Simonsen A (2021)
Autophagy modulates cell fate decisions during lineage commitment
Autophagy, 18 (8), 1915-1931
DOI 10.1080/15548627.2021.2008691, PubMed 34923909

Tvedt THA, Steien E, Øvrebø B, Haaverstad R, Hobbs W, Wardęcki M, Tjønnfjord GE, Berentsen SA (2021)
Sutimlimab, an investigational C1s inhibitor, effectively prevents exacerbation of hemolytic anemia in a patient with cold agglutinin disease undergoing major surgery
Am J Hematol, 97 (2), E51-E54
DOI 10.1002/ajh.26409, PubMed 34778998

Ali M, Giannakopoulou E, Li Y, Lehander M, Virding Culleton S, Yang W, Knetter C, Odabasi MC, Bollineni RC, Yang X, Foldvari Z, Böschen ML, Taraldsrud E, Strønen E, Toebes M, Hillen A, Mazzi S, de Ru AH, Janssen GMC, Kolstad A, Tjønnfjord GE, Lie BA, Griffioen M, Lehmann S, Osnes LT et al. (2021)
T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Nat Biotechnol, 40 (4), 488-498
DOI 10.1038/s41587-021-01089-x, PubMed 34873326

Vedeld HM, Grimsrud MM, Andresen K, Pharo HD, von Seth E, Karlsen TH, Honne H, Paulsen V, Färkkilä MA, Bergquist A, Jeanmougin M, Aabakken L, Boberg KM, Folseraas T, Lind GE (2021)
Early and accurate detection of cholangiocarcinoma in patients with primary sclerosing cholangitis by methylation markers in bile
Hepatology, 75 (1), 59-73
DOI 10.1002/hep.32125, PubMed 34435693

Grigalavicius M, Mastrangelopoulou M, Berg K, Arous D, Ménard M, Raabe-Henriksen T, Brondz E, Siem S, Görgen A, Edin NFJ, Malinen E, Theodossiou TA (2021)
Publisher Correction: Proton-dynamic therapy following photosensitiser activation by accelerated protons demonstrated through fluorescence and singlet oxygen production
Nat Commun, 12 (1), 7073
DOI 10.1038/s41467-021-27175-x, PubMed 34848706

Schink KO, Tan KW, Spangenberg H, Martorana D, Sneeggen M, Stévenin V, Enninga J, Campsteijn C, Raiborg C, Stenmark H (2021)
The phosphoinositide coincidence detector Phafin2 promotes macropinocytosis by coordinating actin organisation at forming macropinosomes
Nat Commun, 12 (1), 6577
DOI 10.1038/s41467-021-26775-x, PubMed 34772942

Engebraaten O, Yau C, Berg K, Borgen E, Garred Ø, Berstad MEB, Fremstedal ASV, DeMichele A, Veer LV', Esserman L, Weyergang A (2021)
RAB5A expression is a predictive biomarker for trastuzumab emtansine in breast cancer
Nat Commun, 12 (1), 6427
DOI 10.1038/s41467-021-26018-z, PubMed 34741021

Munson MJ, Mathai BJ, Ng MYW, Trachsel-Moncho L, de la Ballina LR, Schultz SW, Aman Y, Lystad AH, Singh S, Singh S, Wesche J, Fang EF, Simonsen A (2021)
GAK and PRKCD are positive regulators of PRKN-independent mitophagy
Nat Commun, 12 (1), 6101
DOI 10.1038/s41467-021-26331-7, PubMed 34671015

Martens-Uzunova ES, Blijdorp CJ, Burger D, Erdbrügger U, Llorente A (2021)
Urinary Extracellular Vesicles in Urology: Current Successes and Challenges Ahead
Eur Urol, 81 (1), 127-128
DOI 10.1016/j.eururo.2021.09.025, PubMed 34625312

Lone AM, Giansanti P, Jørgensen MJ, Gjerga E, Dugourd A, Scholten A, Saez-Rodriguez J, Heck AJR, Taskén K (2021)
Systems approach reveals distinct and shared signaling networks of the four PGE₂ receptors in T cells
Sci Signal, 14 (703), eabc8579
DOI 10.1126/scisignal.abc8579, PubMed 34609894

Flatmark K, Torgunrud A, Fleten KG, Davidson B, Juul HV, Mensali N, Lund-Andersen C, Inderberg EM (2021)
Peptide vaccine targeting mutated GNAS: a potential novel treatment for pseudomyxoma peritonei
J Immunother Cancer, 9 (10)
DOI 10.1136/jitc-2021-003109, PubMed 34711663

Schjesvold F, Bringhen S, G Richardson P, Perrot A, Leleu X, Moreau P, A Dimopoulos M, Hulin C, Tekle C, Foster MC, Poole EM, van de Velde H, Facon T (2021)
Isatuximab plus pomalidomide and dexamethasone in frail patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis
Am J Hematol, 96 (11), E423-E427
DOI 10.1002/ajh.26319, PubMed 34383345

Taavitsainen S, Engedal N, Cao S, Handle F, Erickson A, Prekovic S, Wetterskog D, Tolonen T, Vuorinen EM, Kiviaho A, Nätkin R, Häkkinen T, Devlies W, Henttinen S, Kaarijärvi R, Lahnalampi M, Kaljunen H, Nowakowska K, Syvälä H, Bläuer M, Cremaschi P, Claessens F, Visakorpi T, Tammela TLJ, Murtola T et al. (2021)
Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse
Nat Commun, 12 (1), 5307
DOI 10.1038/s41467-021-25624-1, PubMed 34489465

Sveen A, Johannessen B, Eilertsen IA, Røsok BI, Gulla M, Eide PW, Bruun J, Kryeziu K, Meza-Zepeda LA, Myklebost O, Bjørnbeth BA, Skotheim RI, Nesbakken A, Lothe RA (2021)
The expressed mutational landscape of microsatellite stable colorectal cancers
Genome Med, 13 (1), 142
DOI 10.1186/s13073-021-00955-2, PubMed 34470667

Møller P, Sampson JR, Dominguez-Valentin M, Seppälä TT (2021)
Towards evidence-based personalised precision medicine for Lynch syndrome
Lancet Oncol, 22 (9), e383
DOI 10.1016/S1470-2045(21)00400-9, PubMed 34478667

Moosavi SH, Eide PW, Eilertsen IA, Brunsell TH, Berg KCG, Røsok BI, Brudvik KW, Bjørnbeth BA, Guren MG, Nesbakken A, Lothe RA, Sveen A (2021)
De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity
Genome Med, 13 (1), 143
DOI 10.1186/s13073-021-00956-1, PubMed 34470666

Jiang D, Hveem TS, Glaire M, Church DN, Kerr DJ, Yang L, Danielsen HE (2021)
Automated assessment of CD8⁺ T-lymphocytes and stroma fractions complement conventional staging of colorectal cancer
EBioMedicine, 71, 103547
DOI 10.1016/j.ebiom.2021.103547, PubMed 34479131

Khezri R, Holland P, Schoborg TA, Abramovich I, Takáts S, Dillard C, Jain A, O'Farrell F, Schultz SW, Hagopian WM, Quintana EM, Ng R, Katheder NS, Rahman MM, Teles Reis JG, Brech A, Jasper H, Rusan NM, Jahren AH, Gottlieb E, Rusten TE (2021)
Host autophagy mediates organ wasting and nutrient mobilization for tumor growth
EMBO J, 40 (18), e107336
DOI 10.15252/embj.2020107336, PubMed 34309071

Eide PW, Moosavi SH, Eilertsen IA, Brunsell TH, Langerud J, Berg KCG, Røsok BI, Bjørnbeth BA, Nesbakken A, Lothe RA, Sveen A (2021)
Metastatic heterogeneity of the consensus molecular subtypes of colorectal cancer
NPJ Genom Med, 6 (1), 59
DOI 10.1038/s41525-021-00223-7, PubMed 34262039

Pällmann N, Deng K, Livgård M, Tesikova M, Jin Y, Frengen NS, Kahraman N, Mokhlis HM, Ozpolat B, Kildal W, Danielsen HE, Fazli L, Rennie PS, Banerjee PP, Üren A, Jin Y, Kuzu OF, Saatcioglu F (2021)
Stress-Mediated Reprogramming of Prostate Cancer One-Carbon Cycle Drives Disease Progression
Cancer Res, 81 (15), 4066-4078
DOI 10.1158/0008-5472.CAN-20-3956, PubMed 34183356

Dillard P, Casey N, Pollmann S, Vernhoff P, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2021)
Targeting KRAS mutations with HLA class II-restricted TCRs for the treatment of solid tumors
Oncoimmunology, 10 (1), 1936757
DOI 10.1080/2162402X.2021.1936757, PubMed 34235003

Spasevska I, Myklebust JH (2021)
What It Takes to Transform a T Cell
Cancer Res, 81 (12), 3160-3161
DOI 10.1158/0008-5472.CAN-21-0784, PubMed 34224376

Cichońska A, Ravikumar B, Allaway RJ, Wan F, Park S, Isayev O, Li S, Mason M, Lamb A, Tanoli Z, Jeon M, Kim S, Popova M, Capuzzi S, Zeng J, Dang K, Koytiger G, Kang J, Wells CI, Willson TM, IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, Oprea TI, Schlessinger A, Drewry DH, Stolovitzky G et al. (2021)
Crowdsourced mapping of unexplored target space of kinase inhibitors
Nat Commun, 12 (1), 3307
DOI 10.1038/s41467-021-23165-1, PubMed 34083538

Ghanima W, Gernsheimer T, Kuter DJ (2021)
How I treat primary ITP in adult patients who are unresponsive to or dependent on corticosteroid treatment
Blood, 137 (20), 2736-2744
DOI 10.1182/blood.2021010968, PubMed 33827138

Hompland I, Ferrari S, Bielack S, Palmerini E, Hall KS, Picci P, Hecker-Nolting S, Donati DM, Blattmann C, Bjerkehagen B, Staals E, Kager L, Gambarotti M, Kühne T, Eriksson M, Ferraresi V, Kevric M, Biagini R, Baumhoer D, Brosjø O, Comandone A, Schwarz R, Bertulli R, Kessler T, Hansson L et al. (2021)
Outcome in dedifferentiated chondrosarcoma for patients treated with multimodal therapy: Results from the EUROpean Bone Over 40 Sarcoma Study
Eur J Cancer, 151, 150-158
DOI 10.1016/j.ejca.2021.04.017, PubMed 33990016

Małecka A, Trøen G, Delabie J, Małecki J, Østlie I, Tierens A, Randen U, Berentsen S, Tjønnfjord GE (2021)
The mutational landscape of cold agglutinin disease: CARD11 and CXCR4 mutations are correlated with lower hemoglobin levels
Am J Hematol, 96 (8), E279-E283
DOI 10.1002/ajh.26205, PubMed 33891703

Sioud M (2021)
Reducing the immunosuppressive tumor microenvironment enhances photoimmunotherapy efficacy
EBioMedicine, 67, 103351
DOI 10.1016/j.ebiom.2021.103351, PubMed 33965875

Aure MR, Fleischer T, Bjørklund S, Ankill J, Castro-Mondragon JA, OSBREAC, Børresen-Dale AL, Tost J, Sahlberg KK, Mathelier A, Tekpli X, Kristensen VN (2021)
Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer
Genome Med, 13 (1), 72
DOI 10.1186/s13073-021-00880-4, PubMed 33926515

Schultz NH, Sørvoll IH, Michelsen AE, Munthe LA, Lund-Johansen F, Ahlen MT, Wiedmann M, Aamodt AH, Skattør TH, Tjønnfjord GE, Holme PA (2021)
Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
N Engl J Med, 384 (22), 2124-2130
DOI 10.1056/NEJMoa2104882, PubMed 33835768

Schjesvold FH, Richardson PG, Facon T, Alegre A, Spencer A, Jurczyszyn A, Sunami K, Frenzel L, Min CK, Guillonneau S, Lin PL, Le-Guennec S, Campana F, van de Velde H, Bensfia S, Bringhen S (2021)
Isatuximab plus pomalidomide and dexamethasone in elderly patients with relapsed/refractory multiple myeloma: ICARIA-MM subgroup analysis
Haematologica, 106 (4), 1182-1187
DOI 10.3324/haematol.2020.253450, PubMed 32586908

Seppälä TT, Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2021)
Uptake of hysterectomy and bilateral salpingo-oophorectomy in carriers of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Eur J Cancer, 148, 124-133
DOI 10.1016/j.ejca.2021.02.022, PubMed 33743481

Zhen Y, Radulovic M, Vietri M, Stenmark H (2021)
Sealing holes in cellular membranes
EMBO J, 40 (7), e106922
DOI 10.15252/embj.2020106922, PubMed 33644904

Jaiswal A, Gautam P, Pietilä EA, Timonen S, Nordström N, Akimov Y, Sipari N, Tanoli Z, Fleischer T, Lehti K, Wennerberg K, Aittokallio T (2021)
Multi-modal meta-analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor
Mol Syst Biol, 17 (3), e9526
DOI 10.15252/msb.20209526, PubMed 33750001

Schultz SW, Agudo-Canalejo J, Chino H, Migliano SM, Saito C, Koyama-Honda I, Stenmark H, Brech A, Mizushima N, Knorr RL, May AI (2021)
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Autophagy, 17 (4), 1046-1048
DOI 10.1080/15548627.2021.1887548, PubMed 33629888

Akimov Y, Aittokallio T (2021)
Re-defining synthetic lethality by phenotypic profiling for precision oncology
Cell Chem Biol, 28 (3), 246-256
DOI 10.1016/j.chembiol.2021.01.026, PubMed 33631125

Gaustad JV, Simonsen TG, Hansem LMK, Rofstad EK (2021)
Intravital microscopy of tumor vessel morphology and function using a standard fluorescence microscope
Eur J Nucl Med Mol Imaging, 48 (10), 3089-3100
DOI 10.1007/s00259-021-05243-0, PubMed 33606081

Ianevski A, Lahtela J, Javarappa KK, Sergeev P, Ghimire BR, Gautam P, Vähä-Koskela M, Turunen L, Linnavirta N, Kuusanmäki H, Kontro M, Porkka K, Heckman CA, Mattila P, Wennerberg K, Giri AK, Aittokallio T (2021)
Patient-tailored design for selective co-inhibition of leukemic cell subpopulations
Sci Adv, 7 (8)
DOI 10.1126/sciadv.abe4038, PubMed 33608276

Skotland T, Sandvig K (2021)
Transport of nanoparticles across the endothelial cell layer
Nano Today, 36, 101029
DOI 10.1016/j.nantod.2020.101029

Kleppe A, Skrede OJ, De Raedt S, Liestøl K, Kerr DJ, Danielsen HE (2021)
Designing deep learning studies in cancer diagnostics
Nat Rev Cancer, 21 (3), 199-211
DOI 10.1038/s41568-020-00327-9, PubMed 33514930

Liestøl K, Kleppe A, Skrede OJ, De Raedt S, Kerr DJ, Danielsen HE (2021)
Deep learning and cancer biomarkers: recognising lead-time bias - Authors' reply
Lancet, 397 (10270), 194-195
DOI 10.1016/S0140-6736(21)00035-0, PubMed 33453777

Cunha ES, Chen X, Sanz-Gaitero M, Mills DJ, Luecke H (2021)
Cryo-EM structure of Helicobacter pylori urease with an inhibitor in the active site at 2.0 Å resolution
Nat Commun, 12 (1), 230
DOI 10.1038/s41467-020-20485-6, PubMed 33431861

Kummen M, Thingholm LB, Rühlemann MC, Holm K, Hansen SH, Moitinho-Silva L, Liwinski T, Zenouzi R, Storm-Larsen C, Midttun Ø, McCann A, Ueland PM, Høivik ML, Vesterhus M, Trøseid M, Laudes M, Lieb W, Karlsen TH, Bang C, Schramm C, Franke A, Hov JR (2020)
Altered Gut Microbial Metabolism of Essential Nutrients in Primary Sclerosing Cholangitis
Gastroenterology, 160 (5), 1784-1798.e0
DOI 10.1053/j.gastro.2020.12.058, PubMed 33387530

Landsverk HB, Sandquist LE, Bay LTE, Steurer B, Campsteijn C, Landsverk OJB, Marteijn JA, Petermann E, Trinkle-Mulcahy L, Syljuåsen RG (2020)
WDR82/PNUTS-PP1 Prevents Transcription-Replication Conflicts by Promoting RNA Polymerase II Degradation on Chromatin
Cell Rep, 33 (9), 108469
DOI 10.1016/j.celrep.2020.108469, PubMed 33264625

Dominguez-Valentin M, Crosbie EJ, Engel C, Aretz S, Macrae F, Winship I, Capella G, Thomas H, Nakken S, Hovig E, Nielsen M, Sijmons RH, Bertario L, Bonanni B, Tibiletti MG, Cavestro GM, Mints M, Gluck N, Katz L, Heinimann K, Vaccaro CA, Green K, Lalloo F, Hill J, Schmiegel W et al. (2020)
Risk-reducing hysterectomy and bilateral salpingo-oophorectomy in female heterozygotes of pathogenic mismatch repair variants: a Prospective Lynch Syndrome Database report
Genet Med, 23 (4), 705-712
DOI 10.1038/s41436-020-01029-1, PubMed 33257847

Dillard P, Köksal H, Maggadottir SM, Winge-Main A, Pollmann S, Menard M, Myhre MR, Mælandsmo GM, Flørenes VA, Gaudernack G, Kvalheim G, Wälchli S, Inderberg EM (2020)
Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy
Mol Ther, 29 (3), 1199-1213
DOI 10.1016/j.ymthe.2020.11.019, PubMed 33212301

Tinholt M, Stavik B, Tekpli X, Garred Ø, Borgen E, Kristensen V, Sahlberg KK, Sandset PM, Iversen N (2020)
Coagulation factor V is a marker of tumor-infiltrating immune cells in breast cancer
Oncoimmunology, 9 (1), 1824644
DOI 10.1080/2162402X.2020.1824644, PubMed 33457104

Dominguez-Valentin M, Sampson JR, Seppälä TT, Ten Broeke SW, Plazzer JP, Nakken S, Engel C, Aretz S, Jenkins MA, Sunde L, Bernstein I, Capella G, Balaguer F, Thomas H, Evans DG, Burn J, Greenblatt M, Hovig E, de Vos Tot Nederveen Cappel WH, Sijmons RH, Bertario L, Tibiletti MG, Cavestro GM, Lindblom A, Della Valle A et al. (2020)
Correction: Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
Genet Med, 22 (9), 1569
DOI 10.1038/s41436-020-0892-4, PubMed 32690931

Radulovic M, Stenmark H (2020)
LRRK2 to the rescue of damaged endomembranes
EMBO J, 39 (18), e106162
DOI 10.15252/embj.2020106162, PubMed 32803793

Smeby J, Kryeziu K, Berg KCG, Eilertsen IA, Eide PW, Johannessen B, Guren MG, Nesbakken A, Bruun J, Lothe RA, Sveen A (2020)
Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity
EBioMedicine, 59, 102923
DOI 10.1016/j.ebiom.2020.102923, PubMed 32799124

Pedersen NM, Wenzel EM, Wang L, Antoine S, Chavrier P, Stenmark H, Raiborg C (2020)
Protrudin-mediated ER-endosome contact sites promote MT1-MMP exocytosis and cell invasion
J Cell Biol, 219 (8)
DOI 10.1083/jcb.202003063, PubMed 32479595

Berentsen S, Barcellini W, D'Sa S, Randen U, Tvedt THA, Fattizzo B, Haukås E, Kell M, Brudevold R, Dahm AEA, Dalgaard J, Frøen H, Hallstensen RF, Jæger PH, Hjorth-Hansen H, Małecka A, Oksman M, Rolke J, Sekhar M, Sørbø JH, Tjønnfjord E, Tsykunova G, Tjønnfjord GE (2020)
Cold agglutinin disease revisited: a multinational, observational study of 232 patients
Blood, 136 (4), 480-488
DOI 10.1182/blood.2020005674, PubMed 32374875

Ianevski A, Giri AK, Aittokallio T (2020)
SynergyFinder 2.0: visual analytics of multi-drug combination synergies
Nucleic Acids Res, 48 (W1), W488-W493
DOI 10.1093/nar/gkaa216, PubMed 32246720

Hillestad T, Hompland T, Fjeldbo CS, Skingen VE, Salberg UB, Aarnes EK, Nilsen A, Lund KV, Evensen TS, Kristensen GB, Stokke T, Lyng H (2020)
MRI Distinguishes Tumor Hypoxia Levels of Different Prognostic and Biological Significance in Cervical Cancer
Cancer Res, 80 (18), 3993-4003
DOI 10.1158/0008-5472.CAN-20-0950, PubMed 32606004

Vietri M, Schultz SW, Bellanger A, Jones CM, Petersen LI, Raiborg C, Skarpen E, Pedurupillay CRJ, Kjos I, Kip E, Timmer R, Jain A, Collas P, Knorr RL, Grellscheid SN, Kusumaatmaja H, Brech A, Micci F, Stenmark H, Campsteijn C (2020)
Unrestrained ESCRT-III drives micronuclear catastrophe and chromosome fragmentation
Nat Cell Biol, 22 (7), 856-867
DOI 10.1038/s41556-020-0537-5, PubMed 32601372

Fjeldbo CS, Hompland T, Hillestad T, Aarnes EK, Günther CC, Kristensen GB, Malinen E, Lyng H (2020)
Combining imaging- and gene-based hypoxia biomarkers in cervical cancer improves prediction of chemoradiotherapy failure independent of intratumour heterogeneity
EBioMedicine, 57, 102841
DOI 10.1016/j.ebiom.2020.102841, PubMed 32580139

Skotland T, Kavaliauskiene S, Sandvig K (2020)
The role of lipid species in membranes and cancer-related changes
Cancer Metastasis Rev, 39 (2), 343-360
DOI 10.1007/s10555-020-09872-z, PubMed 32314087

Lingelem ABD, Kavaliauskiene S, Halsne R, Klokk TI, Surma MA, Klose C, Skotland T, Sandvig K (2020)
Diacylglycerol kinase and phospholipase D inhibitors alter the cellular lipidome and endosomal sorting towards the Golgi apparatus
Cell Mol Life Sci, 78 (3), 985-1009
DOI 10.1007/s00018-020-03551-6, PubMed 32447426

Dueland S, Line PD (2020)
Response to the Comment on"Survival Following Liver Transplantation for Patients With Non-resectable Liver Only Colorectal Metastases": What if those Lesions Are Gone?
Ann Surg, 271 (5), e124
DOI 10.1097/SLA.0000000000003604, PubMed 32301798

Olsen T, Blomhoff R (2020)
Retinol, Retinoic Acid, and Retinol-Binding Protein 4 are Differentially Associated with Cardiovascular Disease, Type 2 Diabetes, and Obesity: An Overview of Human Studies
Adv Nutr, 11 (3), 644-666
DOI 10.1093/advances/nmz131, PubMed 31868199

Bruun J, Kryeziu K, Eide PW, Moosavi SH, Eilertsen IA, Langerud J, Røsok B, Totland MZ, Brunsell TH, Pellinen T, Saarela J, Bergsland CH, Palmer HG, Brudvik KW, Guren T, Dienstmann R, Guren MG, Nesbakken A, Bjørnbeth BA, Sveen A, Lothe RA (2020)
Patient-Derived Organoids from Multiple Colorectal Cancer Liver Metastases Reveal Moderate Intra-patient Pharmacotranscriptomic Heterogeneity
Clin Cancer Res, 26 (15), 4107-4119
DOI 10.1158/1078-0432.CCR-19-3637, PubMed 32299813

Fougner C, Bergholtz H, Norum JH, Sørlie T (2020)
Re-definition of claudin-low as a breast cancer phenotype
Nat Commun, 11 (1), 1787
DOI 10.1038/s41467-020-15574-5, PubMed 32286297

Malenge MM, Patzke S, Ree AH, Stokke T, Ceuppens P, Middleton B, Dahle J, Repetto-Llamazares AHV (2020)
¹⁷⁷Lu-Lilotomab Satetraxetan Has the Potential to Counteract Resistance to Rituximab in Non-Hodgkin Lymphoma
J Nucl Med, 61 (10), 1468-1475
DOI 10.2967/jnumed.119.237230, PubMed 32245896

Akimov Y, Bulanova D, Timonen S, Wennerberg K, Aittokallio T (2020)
Improved detection of differentially represented DNA barcodes for high-throughput clonal phenomics
Mol Syst Biol, 16 (3), e9195
DOI 10.15252/msb.20199195, PubMed 32187448

Skrede OJ, De Raedt S, Kleppe A, Hveem TS, Liestøl K, Maddison J, Askautrud HA, Pradhan M, Nesheim JA, Albregtsen F, Farstad IN, Domingo E, Church DN, Nesbakken A, Shepherd NA, Tomlinson I, Kerr R, Novelli M, Kerr DJ, Danielsen HE (2020)
Deep learning for prediction of colorectal cancer outcome: a discovery and validation study
Lancet, 395 (10221), 350-360
DOI 10.1016/S0140-6736(19)32998-8, PubMed 32007170

Jin Y, Saatcioglu F (2020)
Targeting the Unfolded Protein Response in Hormone-Regulated Cancers
Trends Cancer, 6 (2), 160-171
DOI 10.1016/j.trecan.2019.12.001, PubMed 32061305

Meås HZ, Haug M, Beckwith MS, Louet C, Ryan L, Hu Z, Landskron J, Nordbø SA, Taskén K, Yin H, Damås JK, Flo TH (2020)
Sensing of HIV-1 by TLR8 activates human T cells and reverses latency
Nat Commun, 11 (1), 147
DOI 10.1038/s41467-019-13837-4, PubMed 31919342

Fornes O, Castro-Mondragon JA, Khan A, van der Lee R, Zhang X, Richmond PA, Modi BP, Correard S, Gheorghe M, Baranašić D, Santana-Garcia W, Tan G, Chèneby J, Ballester B, Parcy F, Sandelin A, Lenhard B, Wasserman WW, Mathelier A (2020)
JASPAR 2020: update of the open-access database of transcription factor binding profiles
Nucleic Acids Res, 48 (D1), D87-D92
DOI 10.1093/nar/gkz1001, PubMed 31701148

Fromm B, Domanska D, Høye E, Ovchinnikov V, Kang W, Aparicio-Puerta E, Johansen M, Flatmark K, Mathelier A, Hovig E, Hackenberg M, Friedländer MR, Peterson KJ (2020)
MirGeneDB 2.0: the metazoan microRNA complement
Nucleic Acids Res, 48 (D1), D132-D141
DOI 10.1093/nar/gkz885, PubMed 31598695