Publications by Tom Eirik Mollnes

627 publications found

Publications 2024

  1. Andersson LI, Sjöström DJ, Quach HQ, Hägerström K, Hurler L, Kajdácsi E, Cervenak L, Prohászka Z, Toonen EJM, Mohlin C, Mollnes TE, Sandgren P, Tjernberg I, Nilsson PH (2024)
    Storage of Transfusion Platelet Concentrates Is Associated with Complement Activation and Reduced Ability of Platelets to Respond to Protease-Activated Receptor-1 and Thromboxane A2 Receptor
    Int J Mol Sci, 25 (2)
    DOI 10.3390/ijms25021091, PubMed 38256162
  2. Barratt-Due A, Pettersen K, Børresdatter-Dahl T, Holter JC, Grønli RH, Dyrhol-Riise AM, Lerum TV, Holten AR, Tonby K, Trøseid M, Skjønsberg OH, Granerud BK, Heggelund L, Kildal AB, Schjalm C, Aaløkken TM, Aukrust P, Ueland T, Mollnes TE, Halvorsen B, NOR‐Solidarity study groupThe Norwegian SARS‐CoV‐2 study group (2024)
    Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients
    J Intern Med, 296 (1), 80-92
    DOI 10.1111/joim.13783, PubMed 38539241
  3. Clarke GJB, Skandsen T, Zetterberg H, Follestad T, Einarsen CE, Vik A, Mollnes TE, Pischke SE, Blennow K, Håberg AK (2024)
    Longitudinal Associations Between Persistent Post-Concussion Symptoms and Blood Biomarkers of Inflammation and CNS-Injury After Mild Traumatic Brain Injury
    J Neurotrauma, 41 (7-8), 862-878
    DOI 10.1089/neu.2023.0419, PubMed 38117157
  4. de Boer E, Sokolova M, Jager NM, Schjalm C, Weiss MG, Liavåg OM, Maassen H, van Goor H, Thorgersen EB, Pettersen K, Christiansen D, Ludviksen JK, Jespersen B, Mollnes TE, Leuvenink HGD, Pischke SE (2024)
    Normothermic Machine Perfusion Reconstitutes Porcine Kidney Tissue Metabolism But Induces an Inflammatory Response, Which Is Reduced by Complement C5 Inhibition
    Transpl Int, 37, 13348
    DOI 10.3389/ti.2024.13348, PubMed 39606689
  5. Fageräng B, Cyranka L, Schjalm C, McAdam KE, Larsen CS, Heinzelbecker J, Gedde-Dahl T, Würzner R, Espevik T, Tjønnfjord GE, Garred P, Barratt-Due A, Tvedt THA, Mollnes TE (2024)
    The function of the complement system remains fully intact throughout the course of allogeneic stem cell transplantation
    Front Immunol, 15, 1422370
    DOI 10.3389/fimmu.2024.1422370, PubMed 38938578
  6. Fageräng B, Götz MP, Cyranka L, Lau C, Nilsson PH, Mollnes TE, Garred P (2024)
    The Inflammatory Response Induced by Aspergillus fumigatus Conidia Is Dependent on Complement Activation: Insight from a Whole Blood Model
    J Innate Immun, 16 (1), 324-336
    DOI 10.1159/000539368, PubMed 38768576
  7. Fageräng B, Lau C, Mc Adam KE, Schjalm C, Christiansen D, Garred P, Nilsson PH, Mollnes TE (2024)
    A novel selective leukocyte depletion human whole blood model reveals the specific roles of monocytes and granulocytes in the cytokine response to Escherichia coli
    J Leukoc Biol, 115 (4), 647-663
    DOI 10.1093/jleuko/qiad151, PubMed 38057165
  8. Farbu BH, Lydersen S, Mohus RM, Ueland T, Mollnes TE, Klepstad P, Langeland H (2024)
    The detrimental effects of intestinal injury mediated by inflammation are limited in cardiac arrest patients: A prospective cohort study
    Resusc Plus, 18, 100639
    DOI 10.1016/j.resplu.2024.100639, PubMed 38666252
  9. Førde JL, Alhourani A, Carey T, Arbab A, Fladmark KE, Skrede S, Mollnes TE, Herfindal L, Hagland HR (2024)
    Impact of the Graphene Production Methods Sonication and Microfluidization on In Vitro and In Vivo Toxicity, Macrophage Response, and Complement Activation
    ACS Omega, 9 (39), 40468-40476
    DOI 10.1021/acsomega.4c03189, PubMed 39372034
  10. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2024)
    Retraction Note: Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
    Sci Rep, 14 (1), 3704
    DOI 10.1038/s41598-024-54117-6, PubMed 38355714
  11. Kristiansen S, Jarmund AH, Hilmo J, Mollnes TE, Leth-Olsen M, Nyrnes SA, Nilsen BA, Grønli RH, Faldaas BO, Storm B, Espenes A, Nielsen EW (2024)
    Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain
    JB JS Open Access, 9 (1)
    DOI 10.2106/JBJS.OA.23.00128, PubMed 38419616
  12. Kristiansen S, Storm BS, Emblem ÅE, Grønli RH, Pettersen K, Hilmo J, Jarmund AH, Leth-Olsen M, Nyrnes SA, Nilsen BA, Nielsen EW, Mollnes TE (2024)
    Femoral nailing associated with bone marrow emboli in pigs induced a specific increase in blood IL-6 and broad inflammatory responses in the heart and lungs
    Front Immunol, 15, 1396800
    DOI 10.3389/fimmu.2024.1396800, PubMed 39100680
  13. Marsh PL, Moore EE, Moore HB, Bunch CM, Aboukhaled M, Condon SM, Al-Fadhl MD, Thomas SJ, Larson JR, Bower CW, Miller CB, Pearson ML, Twilling CL, Reser DW, Kim GS, Troyer BM, Yeager D, Thomas SG, Srikureja DP, Patel SS, Añón SL, Thomas AV, Miller JB, Van Ryn DE, Pamulapati SV et al. (2024)
    Corrigendum: Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies
    Front Immunol, 15, 1378003
    DOI 10.3389/fimmu.2024.1378003, PubMed 38380313
  14. Mert Ü, Groven RVM, Greven J, He Z, Mahmoud MA, van Griensven M, Huber-Lang M, Mollnes TE, Rosado Balmayor E, Horst K, Hildebrand F (2024)
    Damage Control Orthopaedics Induced Less Trauma-Induced Coagulopathy than Early Total Care in a Porcine Polytrauma Model
    Eur Surg Res, 65 (1), 115-122
    DOI 10.1159/000541399, PubMed 39348804
  15. Nygaard-Odeh K, Soloy-Nilsen H, Kristiansen MG, Brekke OL, Mollnes TE, Berk M, Bramness JG, Oiesvold T (2024)
    Cytokines in hepatitis C-infected patients with or without opioid maintenance therapy
    Acta Neuropsychiatr, 1-7 (in press)
    DOI 10.1017/neu.2023.56, PubMed 38173235
  16. Roos J, Zinngrebe J, Huber-Lang M, Lupu L, Schmidt MA, Strobel H, Westhoff MA, Stifel U, Gebhard F, Wabitsch M, Mollnes TE, Debatin KM, Halbgebauer R, Fischer-Posovszky P (2024)
    Trauma-associated extracellular histones mediate inflammation via a MYD88-IRAK1-ERK signaling axis and induce lytic cell death in human adipocytes
    Cell Death Dis, 15 (4), 285
    DOI 10.1038/s41419-024-06676-9, PubMed 38653969
  17. Volstad KB, Pripp AH, Ludviksen JA, Stiris T, Saugstad OD, Mollnes TE, Andresen JH (2024)
    No Short-Term Effect of Low-Dose Nicotine on Inflammation after Global Hypoxia in Newborn Piglets
    Neonatology, 1-10 (in press)
    DOI 10.1159/000541217, PubMed 39317175
  18. Weiss MG, de Jong AM, Seegert H, Moeslund N, Maassen H, Schjalm C, de Boer E, Leuvenink H, Mollnes TE, Eijken M, Keller AK, Dijkstra G, Jespersen B, Pischke SE (2024)
    Activation of the Innate Immune System in Brain-Dead Donors Can Be Reduced by Luminal Intestinal Preservation During Organ Procurement Surgery - A Porcine Model
    Transpl Int, 37, 13569
    DOI 10.3389/ti.2024.13569, PubMed 39544322
  19. Zhou N, Groven RVM, Horst K, Mert Ü, Greven J, Mollnes TE, Huber-Lang M, van Griensven M, Hildebrand F, Balmayor ER (2024)
    Pulmonary miRNA expression after polytrauma depends on the surgical invasiveness and displays an anti-inflammatory pattern by the combined inhibition of C5 and CD14
    Front Immunol, 15, 1402571
    DOI 10.3389/fimmu.2024.1402571, PubMed 39267761

Publications 2023

  1. Askarian F, Tsai CM, Cordara G, Zurich RH, Bjånes E, Golten O, Vinther Sørensen H, Kousha A, Meier A, Chikwati E, Bruun JA, Ludviksen JA, Choudhury B, Trieu D, Davis S, Edvardsen PKT, Mollnes TE, Liu GY, Krengel U, Conrad DJ, Vaaje-Kolstad G, Nizet V (2023)
    Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia
    Proc Natl Acad Sci U S A, 120 (30), e2301538120
    DOI 10.1073/pnas.2301538120, PubMed 37459522
  2. Bayly-Jones C, Ho BHT, Lau C, Leung EWW, D'Andrea L, Lupton CJ, Ekkel SM, Venugopal H, Whisstock JC, Mollnes TE, Spicer BA, Dunstone MA (2023)
    The neoepitope of the complement C5b-9 Membrane Attack Complex is formed by proximity of adjacent ancillary regions of C9
    Commun Biol, 6 (1), 42
    DOI 10.1038/s42003-023-04431-y, PubMed 36639734
  3. Bjerkhaug AU, Granslo HN, Cavanagh JP, Høiland I, Ludviksen JK, Lau C, Espevik T, Mollnes TE, Klingenberg C (2023)
    Dual inhibition of complement C5 and CD14 attenuates inflammation in a cord blood model
    Pediatr Res, 94 (2), 512-519
    DOI 10.1038/s41390-023-02489-2, PubMed 36725909
  4. Chaban V, de Boer E, McAdam KE, Vaage J, Mollnes TE, Nilsson PH, Pischke SE, Islam R (2023)
    Escherichia coli-induced inflammatory responses are temperature-dependent in human whole blood ex vivo
    Mol Immunol, 157, 70-77
    DOI 10.1016/j.molimm.2023.03.006, PubMed 37001293
  5. Cyranka L, Mariegaard I, Skjødt MO, Bayarri-Olmos R, Mollnes TE, Garred P, Rosbjerg A (2023)
    Functional Analysis of a Novel Complement C5a Receptor 1-Blocking Monoclonal Antibody
    J Innate Immun, 15 (1), 836-849
    DOI 10.1159/000535084, PubMed 37952515
  6. Førde JL, Herfindal L, Myhr KM, Torkildsen Ø, Mollnes TE, Skrede S (2023)
    Ocrelizumab and ofatumumab, but not rituximab, trigger complement induction in vitro
    Int Immunopharmacol, 124 (Pt B), 111021
    DOI 10.1016/j.intimp.2023.111021, PubMed 37816262
  7. Gerogianni A, Bal M, Mohlin C, Woodruff TM, Lambris JD, Mollnes TE, Sjöström DJ, Nilsson PH (2023)
    In vitro evaluation of iron oxide nanoparticle-induced thromboinflammatory response using a combined human whole blood and endothelial cell model
    Front Immunol, 14, 1101387
    DOI 10.3389/fimmu.2023.1101387, PubMed 37081885
  8. Gramstad OR, Schjalm C, Mollnes TE, Nielsen EW (2023)
    Increased thromboinflammatory load in hereditary angioedema
    Clin Exp Immunol, 214 (2), 170-181
    DOI 10.1093/cei/uxad091, PubMed 37561062
  9. Grover SP, Snir O, Hindberg K, Englebert TM, Braekkan SK, Morelli VM, Jensen SB, Wolberg AS, Mollnes TE, Ueland T, Mackman N, Hansen JB (2023)
    High plasma levels of C1-inhibitor are associated with lower risk of future venous thromboembolism
    J Thromb Haemost, 21 (7), 1849-1860
    DOI 10.1016/j.jtha.2023.03.024, PubMed 37003465
  10. Heldal TF, Åsberg A, Ueland T, Reisæter AV, Pischke SE, Mollnes TE, Aukrust P, Reinholt F, Hartmann A, Heldal K, Jenssen TG (2023)
    Systemic inflammation early after kidney transplantation is associated with long-term graft loss: a cohort study
    Front Immunol, 14, 1253991
    DOI 10.3389/fimmu.2023.1253991, PubMed 37849758
  11. Horst K, Mollnes TE, Huber-Lang M, Hildebrand F (2023)
    Editorial: Organ cross talk and its impact on the clinical course in multiple trauma and critical illness
    Front Immunol, 14, 1195371
    DOI 10.3389/fimmu.2023.1195371, PubMed 37090701
  12. Marsh PL, Moore EE, Moore HB, Bunch CM, Aboukhaled M, Condon SM, Al-Fadhl MD, Thomas SJ, Larson JR, Bower CW, Miller CB, Pearson ML, Twilling CL, Reser DW, Kim GS, Troyer BM, Yeager D, Thomas SG, Srikureja DP, Patel SS, Añón SL, Thomas AV, Miller JB, Van Ryn DE, Pamulapati SV et al. (2023)
    Iatrogenic air embolism: pathoanatomy, thromboinflammation, endotheliopathy, and therapies
    Front Immunol, 14, 1230049
    DOI 10.3389/fimmu.2023.1230049, PubMed 37795086
  13. Maassen H, Venema LH, Weiss MG, Huijink TM, Hofker HS, Keller AK, Mollnes TE, Eijken M, Pischke SE, Jespersen B, van Goor H, Leuvenink HGD (2023)
    H2S-Enriched Flush out Does Not Increase Donor Organ Quality in a Porcine Kidney Perfusion Model
    Antioxidants (Basel), 12 (3)
    DOI 10.3390/antiox12030749, PubMed 36978997
  14. Rydenfelt K, Kjøsen G, Horneland R, Krey Ludviksen J, Jenssen TG, Line PD, Tønnessen TI, Mollnes TE, Haugaa H, Pischke SE (2023)
    Local Postoperative Graft Inflammation in Pancreas Transplant Patients With Early Graft Thrombosis
    Transplant Direct, 10 (1), e1567
    DOI 10.1097/TXD.0000000000001567, PubMed 38094132
  15. Rydenfelt K, Kjøsen G, Horneland R, Ludviksen JK, Jenssen TG, Line PD, Tønnessen TI, Mollnes TE, Haugaa H, Pischke SE (2023)
    Thromboinflammatory response is increased in pancreas transplant alone versus simultaneous pancreas-kidney transplantation and early pancreas graft thrombosis is associated with complement activation
    Front Immunol, 14, 1044444
    DOI 10.3389/fimmu.2023.1044444, PubMed 37063904
  16. Sandvig HV, Aam S, Alme KN, Askim T, Beyer MK, Ellekjær H, Ihle-Hansen H, Lydersen S, Mollnes TE, Munthe-Kaas R, Næss H, Saltvedt I, Seljeseth YM, Thingstad P, Wethal T, Knapskog AB (2023)
    Plasma Inflammatory Biomarkers Are Associated With Poststroke Cognitive Impairment: The Nor-COAST Study
    Stroke, 54 (5), 1303-1311
    DOI 10.1161/STROKEAHA.122.041965, PubMed 37026459
  17. Selvakumar J, Havdal LB, Drevvatne M, Brodwall EM, Lund Berven L, Stiansen-Sonerud T, Einvik G, Leegaard TM, Tjade T, Michelsen AE, Mollnes TE, Lund-Johansen F, Holmøy T, Zetterberg H, Blennow K, Sandler CX, Cvejic E, Lloyd AR, Wyller VBB (2023)
    Prevalence and Characteristics Associated With Post-COVID-19 Condition Among Nonhospitalized Adolescents and Young Adults
    JAMA Netw Open, 6 (3), e235763
    DOI 10.1001/jamanetworkopen.2023.5763, PubMed 36995712
  18. Sikkeland LIB, Ueland T, Lund MB, Durheim MT, Mollnes TE (2023)
    A role for the terminal C5-C9 complement pathway in idiopathic pulmonary fibrosis
    Front Med (Lausanne), 10, 1236495
    DOI 10.3389/fmed.2023.1236495, PubMed 37621463
  19. Skjeflo EW, Evensen LH, Jensen SB, Latysheva N, Michelsen A, Ueland T, Brækkan SK, Hindberg K, Snir O, Mollnes TE, Hansen JB (2023)
    Complement factors B, D, C3bBbP and risk of future venous thromboembolism
    Clin Immunol, 249, 109278
    DOI 10.1016/j.clim.2023.109278, PubMed 36894046
  20. Soloey-Nilsen H, Nygaard-Odeh K, Kristiansen MG, Kvig EI, Brekke OL, Mollnes TE, Berk M, Reitan SK, Oiesvold T (2023)
    Transdiagnostic Associations between Anger Hostility and Chemokine Interferon-gamma Inducible Protein 10
    Clin Psychopharmacol Neurosci, 22 (2), 285-294
    DOI 10.9758/cpn.23.1091, PubMed 38627075
  21. Sommen SL, Havdal LB, Selvakumar J, Einvik G, Leegaard TM, Lund-Johansen F, Michelsen AE, Mollnes TE, Stiansen-Sonerud T, Tjade T, Wyller VBB, Berven LL (2023)
    Inflammatory markers and pulmonary function in adolescents and young adults 6 months after mild COVID-19
    Front Immunol, 13, 1081718
    DOI 10.3389/fimmu.2022.1081718, PubMed 36685555
  22. Thorgersen EB, Asvall J, Schjalm C, McAdam KE, Bruland ØS, Larsen SG, Mollnes TE (2023)
    Effect of Intraperitoneal 224Radium-Labelled Microparticles on Compartmentalized Inflammation After Cytoreductive Surgery and Hypertherm Intraperitoneal Chemotherapy
    Technol Cancer Res Treat, 22, 15330338231192902
    DOI 10.1177/15330338231192902, PubMed 37574949
  23. Wang B, Wöhler A, Greven J, Salzmann RJS, Keller CM, Tertel T, Zhao Q, Mert Ü, Horst K, Lupu L, Huber-Lang M, van Griensven M, Mollnes TE, Schaaf S, Schwab R, Strassburg CP, Schmidt-Wolf IGH, Giebel B, Hildebrand F, Lukacs-Kornek V, Willms AG, Kornek MT (2023)
    Liquid Biopsy in Organ Damage: small extracellular vesicle chip-based assessment of polytrauma
    Front Immunol, 14, 1279496
    DOI 10.3389/fimmu.2023.1279496, PubMed 38035093

Publications 2022

  1. Bugge E, Wynn R, Mollnes TE, Reitan SK, Lapid M, Grønli OK (2022)
    C-reactive protein levels and depression in older and younger adults - A study of 19,947 individuals. The Tromsø study
    Brain Behav Immun Health, 27, 100571
    DOI 10.1016/j.bbih.2022.100571, PubMed 36583067
  2. Damoah CE, Snir O, Hindberg K, Garred P, Ludviksen JK, Brækkan SK, Morelli VM, Mollnes TE, Hansen JB, INVENT Consortium (2022)
    High Levels of Complement Activating Enzyme MASP-2 Are Associated With the Risk of Future Incident Venous Thromboembolism
    Arterioscler Thromb Vasc Biol, 42 (9), 1186-1197
    DOI 10.1161/ATVBAHA.122.317746, PubMed 35861070
  3. de Boer E, Sokolova M, Quach HQ, McAdam KE, Götz MP, Chaban V, Vaage J, Fageräng B, Woodruff TM, Garred P, Nilsson PH, Mollnes TE, Pischke SE (2022)
    Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release
    J Immunol, 209 (9), 1760-1767
    DOI 10.4049/jimmunol.2101191, PubMed 36104112
  4. Emblem Å, Knutsen E, Jørgensen TE, Fure H, Johansen SD, Brekke OL, Mollnes TE, Karlsen BO (2022)
    Blood Transcriptome Analysis of Septic Patients Reveals a Long Non-Coding Alu-RNA in the Complement C5a Receptor 1 Gene
    Noncoding RNA, 8 (2)
    DOI 10.3390/ncrna8020024, PubMed 35447887
  5. Gerogianni A, Dimitrov JD, Zarantonello A, Poillerat V, Chonat S, Sandholm K, McAdam KE, Ekdahl KN, Mollnes TE, Mohlin C, Roumenina LT, Nilsson PH (2022)
    Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation
    Front Immunol, 13, 901876
    DOI 10.3389/fimmu.2022.901876, PubMed 35935964
  6. Habberstad R, Aass N, Mollnes TE, Damås JK, Brunelli C, Rossi R, Garcia-Alonso E, Kaasa S, Klepstad P (2022)
    Inflammatory Markers and Radiotherapy Response in Patients With Painful Bone Metastases
    J Pain Symptom Manage, 64 (4), 330-339
    DOI 10.1016/j.jpainsymman.2022.06.018, PubMed 35803553
  7. Heldal TF, Åsberg A, Ueland T, Reisaeter AV, Pischke SE, Mollnes TE, Aukrust P, Hartmann A, Heldal K, Jenssen T (2022)
    Inflammation in the early phase after kidney transplantation is associated with increased long-term all-cause mortality
    Am J Transplant, 22 (8), 2016-2027
    DOI 10.1111/ajt.17047, PubMed 35352462
  8. Jager NM, Venema LH, Arykbaeva AS, Meter-Arkema AH, Ottens PJ, van Kooten C, Mollnes TE, Alwayn IPJ, Leuvenink HGD, Pischke SE, PROPER study consortium (2022)
    Complement Is Activated During Normothermic Machine Perfusion of Porcine and Human Discarded Kidneys
    Front Immunol, 13, 831371
    DOI 10.3389/fimmu.2022.831371, PubMed 35911712
  9. Johnson C, Quach HQ, Lau C, Ekholt K, Espevik T, Woodruff TM, Pischke SE, Mollnes TE, Nilsson PH (2022)
    Thrombin Differentially Modulates the Acute Inflammatory Response to Escherichia coli and Staphylococcus aureus in Human Whole Blood
    J Immunol, 208 (12), 2771-2778
    DOI 10.4049/jimmunol.2101033, PubMed 35675954
  10. Landsem A, Emblem Å, Lau C, Christiansen D, Gerogianni A, Karlsen BO, Mollnes TE, Nilsson PH, Brekke OL (2022)
    Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood
    Front Immunol, 13, 1020712
    DOI 10.3389/fimmu.2022.1020712, PubMed 36591264
  11. Lund Berven L, Selvakumar J, Havdal L, Stiansen-Sonerud T, Einvik G, Leegaard TM, Tjade T, Michelsen AE, Mollnes TE, Wyller VBB (2022)
    Inflammatory Markers, Pulmonary Function, and Clinical Symptoms in Acute COVID-19 Among Non-Hospitalized Adolescents and Young Adults
    Front Immunol, 13, 837288
    DOI 10.3389/fimmu.2022.837288, PubMed 35222429
  12. Lupu L, Horst K, Greven J, Mert Ü, Ludviksen JAK, Pettersen K, Lau C, Li Y, Palmer A, Qin K, Zhang X, Mayer B, van Griensven M, Huber-Lang M, Hildebrand F, Mollnes TE (2022)
    Simultaneous C5 and CD14 inhibition limits inflammation and organ dysfunction in pig polytrauma
    Front Immunol, 13, 952267
    DOI 10.3389/fimmu.2022.952267, PubMed 36059503
  13. Medeiros PMC, Schjalm C, Christiansen D, Sokolova M, Pischke SE, Würzner R, Mollnes TE, Barratt-Due A (2022)
    Vitamin C, Hydrocortisone, and the Combination Thereof Significantly Inhibited Two of Nine Inflammatory Markers Induced by Escherichia Coli But Not by Staphylococcus Aureus - When Incubated in Human Whole Blood
    Shock, 57 (1), 72-80
    DOI 10.1097/SHK.0000000000001834, PubMed 34265830
  14. Mollnes TE, Storm BS, Brekke OL, Nilsson PH, Lambris JD (2022)
    Application of the C3 inhibitor compstatin in a human whole blood model designed for complement research - 20 years of experience and future perspectives
    Semin Immunol, 59, 101604
    DOI 10.1016/j.smim.2022.101604, PubMed 35570131
  15. Nguyen THP, Hokstad I, Fagerland MW, Mollnes TE, Hollan I, Feinberg MW, Hjeltnes G, Eilertsen GØ, Mikkelsen K, Agewall S (2022)
    Antirheumatic therapy is associated with reduced complement activation in rheumatoid arthritis
    PLoS One, 17 (2), e0264628
    DOI 10.1371/journal.pone.0264628, PubMed 35213675
  16. Nielsen EW, Miller Y, Brekke OL, Grond J, Duong AH, Fure H, Ludviksen JK, Pettersen K, Reubsaet L, Solberg R, Johansen HT, Mollnes TE (2022)
    A Novel Porcine Model of Ischemia-Reperfusion Injury After Cross-Clamping the Thoracic Aorta Revealed Substantial Cardiopulmonary, Thromboinflammatory and Biochemical Changes Without Effect of C1-Inhibitor Treatment
    Front Immunol, 13, 852119
    DOI 10.3389/fimmu.2022.852119, PubMed 35432333
  17. Quach HQ, Johnson C, Ekholt K, Islam R, Mollnes TE, Nilsson PH (2022)
    Platelet-Depletion of Whole Blood Reveals That Platelets Potentiate the Release of IL-8 From Leukocytes Into Plasma in a Thrombin-Dependent Manner
    Front Immunol, 13, 865386
    DOI 10.3389/fimmu.2022.865386, PubMed 35444648
  18. Soloey-Nilsen H, Nygaard-Odeh K, Kristiansen MG, Brekke OL, Mollnes TE, Reitan SK, Oiesvold T (2022)
    Association between brain-derived neurotropic factor (BDNF), high-sensitivity C-reactive protein (hs-CRP) and psychiatric symptoms in medicated and unmedicated patients
    BMC Psychiatry, 22 (1), 84
    DOI 10.1186/s12888-022-03744-2, PubMed 35114967
  19. Storjord E, Airila-Månsson S, Karlsen K, Madsen M, Dahl JA, Landsem A, Fure H, Ludviksen JK, Fjøse JØ, Dickey AK, Karlsen BO, Waage Nielsen E, Mollnes TE, Brekke OL (2022)
    Dental and Periodontal Health in Acute Intermittent Porphyria
    Life (Basel), 12 (8)
    DOI 10.3390/life12081270, PubMed 36013449
  20. Storm BS, Ludviksen JK, Christiansen D, Fure H, Pettersen K, Landsem A, Nilsen BA, Dybwik K, Braaten T, Nielsen EW, Mollnes TE (2022)
    Venous Air Embolism Activates Complement C3 Without Corresponding C5 Activation and Trigger Thromboinflammation in Pigs
    Front Immunol, 13, 839632
    DOI 10.3389/fimmu.2022.839632, PubMed 35371063
  21. Torp MK, Ranheim T, Schjalm C, Hjorth M, Heiestad CM, Dalen KT, Nilsson PH, Mollnes TE, Pischke SE, Lien E, Vaage J, Yndestad A, Stensløkken KO (2022)
    Intracellular Complement Component 3 Attenuated Ischemia-Reperfusion Injury in the Isolated Buffer-Perfused Mouse Heart and Is Associated With Improved Metabolic Homeostasis
    Front Immunol, 13, 870811
    DOI 10.3389/fimmu.2022.870811, PubMed 35432387

Publications 2021

  1. Alme KN, Askim T, Assmus J, Mollnes TE, Naik M, Næss H, Saltvedt I, Ueland PM, Ulvik A, Knapskog AB (2021)
    Investigating novel biomarkers of immune activation and modulation in the context of sedentary behaviour: a multicentre prospective ischemic stroke cohort study
    BMC Neurol, 21 (1), 318
    DOI 10.1186/s12883-021-02343-0, PubMed 34399717
  2. Alme KN, Ulvik A, Askim T, Assmus J, Mollnes TE, Naik M, Næss H, Saltvedt I, Ueland PM, Knapskog AB (2021)
    Neopterin and kynurenic acid as predictors of stroke recurrence and mortality: a multicentre prospective cohort study on biomarkers of inflammation measured three months after ischemic stroke
    BMC Neurol, 21 (1), 476
    DOI 10.1186/s12883-021-02498-w, PubMed 34879833
  3. Askarian F, Uchiyama S, Masson H, Sørensen HV, Golten O, Bunæs AC, Mekasha S, Røhr ÅK, Kommedal E, Ludviksen JA, Arntzen MØ, Schmidt B, Zurich RH, van Sorge NM, Eijsink VGH, Krengel U, Mollnes TE, Lewis NE, Nizet V, Vaaje-Kolstad G (2021)
    The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection
    Nat Commun, 12 (1), 1230
    DOI 10.1038/s41467-021-21473-0, PubMed 33623002
  4. Chaban V, Nakstad ER, Stær-Jensen H, Schjalm C, Seljeflot I, Vaage J, Lundqvist C, Benth JŠ, Sunde K, Mollnes TE, Andersen GØ, Pischke SE (2021)
    Complement activation is associated with poor outcome after out-of-hospital cardiac arrest
    Resuscitation, 166, 129-136
    DOI 10.1016/j.resuscitation.2021.05.038, PubMed 34126135
  5. Debler L, Palmer A, Braumüller S, Klohs B, Mollnes TE, Holzmann K, Huber-Lang M, Halbgebauer R (2021)
    Hemorrhagic Shock Induces a Rapid Transcriptomic Shift of the Immune Balance in Leukocytes after Experimental Multiple Injury
    Mediators Inflamm, 2021, 6654318
    DOI 10.1155/2021/6654318, PubMed 33574730
  6. Fevang B, Wyller VBB, Mollnes TE, Pedersen M, Asprusten TT, Michelsen A, Ueland T, Otterdal K (2021)
    Lasting Immunological Imprint of Primary Epstein-Barr Virus Infection With Associations to Chronic Low-Grade Inflammation and Fatigue
    Front Immunol, 12, 715102
    DOI 10.3389/fimmu.2021.715102, PubMed 34987499
  7. Garred P, Tenner AJ, Mollnes TE (2021)
    Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics
    Pharmacol Rev, 73 (2), 792-827
    DOI 10.1124/pharmrev.120.000072, PubMed 33687995
  8. Grimnes G, Bhoelan S, Hindberg K, Davids M, Nieuwdorp M, Mollnes TE, Michelsen AE, Ueland T, Brækkan SK, Hansen JB, Tichelaar V (2021)
    Impact of a Vancomycin-Induced Shift of the Gut Microbiome in a Gram-Negative Direction on Plasma Factor VIII:C Levels: Results from a Randomized Controlled Trial
    Thromb Haemost, 122 (4), 540-551
    DOI 10.1055/s-0041-1733906, PubMed 34428832
  9. Holt MF, Michelsen AE, Shahini N, Bjørkelund E, Bendz CH, Massey RJ, Schjalm C, Halvorsen B, Broch K, Ueland T, Gullestad L, Nilsson PH, Aukrust P, Mollnes TE, Louwe MC (2021)
    The Alternative Complement Pathway Is Activated Without a Corresponding Terminal Pathway Activation in Patients With Heart Failure
    Front Immunol, 12, 800978
    DOI 10.3389/fimmu.2021.800978, PubMed 35003128
  10. Islam R, Islam MM, Nilsson PH, Mohlin C, Hagen KT, Paschalis EI, Woods RL, Bhowmick SC, Dohlman CH, Espevik T, Chodosh J, Gonzalez-Andrades M, Mollnes TE (2021)
    Combined blockade of complement C5 and TLR co-receptor CD14 synergistically inhibits pig-to-human corneal xenograft induced innate inflammatory responses
    Acta Biomater, 127, 169-179
    DOI 10.1016/j.actbio.2021.03.047, PubMed 33785451
  11. Langeland H, Damås JK, Mollnes TE, Ludviksen JK, Ueland T, Michelsen AE, Løberg M, Bergum D, Nordseth T, Skjærvold NK, Klepstad P (2021)
    The inflammatory response is related to circulatory failure after out-of-hospital cardiac arrest: A prospective cohort study
    Resuscitation, 170, 115-125
    DOI 10.1016/j.resuscitation.2021.11.026, PubMed 34838662
  12. Macpherson A, Laabei M, Ahdash Z, Graewert MA, Birtley JR, Schulze ME, Crennell S, Robinson SA, Holmes B, Oleinikovas V, Nilsson PH, Snowden J, Ellis V, Mollnes TE, Deane CM, Svergun D, Lawson AD, van den Elsen JM (2021)
    The allosteric modulation of complement C5 by knob domain peptides
    Elife, 10
    DOI 10.7554/eLife.63586, PubMed 33570492
  13. Nilsson PH, Johnson C, Quach QH, Macpherson A, Durrant O, Pischke SE, Fure H, Landsem A, Bergseth G, Schjalm C, Haugaard-Kedström LM, Huber-Lang M, van den Elsen J, Brekke OL, Mollnes TE (2021)
    A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity
    J Immunol, 207 (6), 1641-1651
    DOI 10.4049/jimmunol.2001471, PubMed 34380648
  14. Nilsson PH, Pettersen K, Oppermann M, Skjeflo EW, Fure H, Christiansen D, Mollnes TE (2021)
    Quantification of Porcine Complement Activation Fragment C3a by a Neoepitope-Based Enzyme-Linked Immunosorbent Assay
    Methods Mol Biol, 2227, 51-59
    DOI 10.1007/978-1-0716-1016-9_5, PubMed 33847930
  15. Niyonzima N, Rahman J, Kunz N, West EE, Freiwald T, Desai JV, Merle NS, Gidon A, Sporsheim B, Lionakis MS, Evensen K, Lindberg B, Skagen K, Skjelland M, Singh P, Haug M, Ruseva MM, Kolev M, Bibby J, Marshall O, O'Brien B, Deeks N, Afzali B, Clark RJ, Woodruff TM et al. (2021)
    Mitochondrial C5aR1 activity in macrophages controls IL-1β production underlying sterile inflammation
    Sci Immunol, 6 (66), eabf2489
    DOI 10.1126/sciimmunol.abf2489, PubMed 34932384
  16. Pethő Á, Piecha D, Mészáros T, Urbanics R, Moore C, Canaud B, Rosivall L, Mollnes TE, Steppan S, Szénási G, Szebeni J, Dézsi L (2021)
    A porcine model of hemodialyzer reactions: roles of complement activation and rinsing back of extracorporeal blood
    Ren Fail, 43 (1), 1609-1620
    DOI 10.1080/0886022X.2021.2007127, PubMed 34882053
  17. Rognes IN, Pischke SE, Ottestad W, Røislien J, Berg JP, Johnson C, Eken T, Mollnes TE (2021)
    Increased complement activation 3 to 6 h after trauma is a predictor of prolonged mechanical ventilation and multiple organ dysfunction syndrome: a prospective observational study
    Mol Med, 27 (1), 35
    DOI 10.1186/s10020-021-00286-3, PubMed 33832430
  18. Sharifi S, Islam MM, Sharifi H, Islam R, Huq TN, Nilsson PH, Mollnes TE, Tran KD, Patzer C, Dohlman CH, Patra HK, Paschalis EI, Gonzalez-Andrades M, Chodosh J (2021)
    Electron Beam Sterilization of Poly(Methyl Methacrylate)-Physicochemical and Biological Aspects
    Macromol Biosci, 21 (4), e2000379
    DOI 10.1002/mabi.202000379, PubMed 33624923
  19. Sharifi S, Islam MM, Sharifi H, Islam R, Koza D, Reyes-Ortega F, Alba-Molina D, Nilsson PH, Dohlman CH, Mollnes TE, Chodosh J, Gonzalez-Andrades M (2021)
    Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications
    Bioact Mater, 6 (11), 3947-3961
    DOI 10.1016/j.bioactmat.2021.03.042, PubMed 33937594
  20. Skjeflo EW, Brækkan SK, Ludviksen JK, Snir O, Hindberg K, Mollnes TE, Hansen JB (2021)
    Elevated plasma concentration of complement factor C5 is associated with risk of future venous thromboembolism
    Blood, 138 (21), 2129-2137
    DOI 10.1182/blood.2021010822, PubMed 34339498
  21. Skovdahl HK, Gopalakrishnan S, Svendsen TD, Granlund AVB, Bakke I, Ginbot ZG, Thorsvik S, Flatberg A, Sporsheim B, Ostrop J, Mollnes TE, Sandvik AK, Bruland T (2021)
    Patient Derived Colonoids as Drug Testing Platforms-Critical Importance of Oxygen Concentration
    Front Pharmacol, 12, 679741
    DOI 10.3389/fphar.2021.679741, PubMed 34054553
  22. Storm BS, Christiansen D, Fure H, Ludviksen JK, Lau C, Lambris JD, Woodruff TM, Brekke OL, Braaten T, Nielsen EW, Mollnes TE (2021)
    Air Bubbles Activate Complement and Trigger Hemostasis and C3-Dependent Cytokine Release Ex Vivo in Human Whole Blood
    J Immunol, 207 (11), 2828-2840
    DOI 10.4049/jimmunol.2100308, PubMed 34732467
  23. Storm BS, Halvorsen PS, Skulstad H, Dybwik K, Schjalm C, Christiansen D, Wisløff-Aase K, Fosse E, Braaten T, Nielsen EW, Mollnes TE (2021)
    Open chest and pericardium facilitate transpulmonary passage of venous air emboli
    Acta Anaesthesiol Scand, 65 (5), 648-655
    DOI 10.1111/aas.13796, PubMed 33595102
  24. Sundnes O, Ottestad W, Schjalm C, Lundbäck P, la Cour Poulsen L, Mollnes TE, Haraldsen G, Eken T (2021)
    Rapid systemic surge of IL-33 after severe human trauma: a prospective observational study
    Mol Med, 27 (1), 29
    DOI 10.1186/s10020-021-00288-1, PubMed 33771098
  25. Thomas AM, Chaban V, Pischke SE, Orrem HL, Bosnes V, Sunde K, Seljeflot I, Lundqvist C, Nakstad ER, Andersen GØ, Schjalm C, Mollnes TE, Barratt-Due A (2021)
    Complement ratios C3bc/C3 and sC5b-9/C5 do not increase the sensitivity of detecting acute complement activation systemically
    Mol Immunol, 141, 273-279
    DOI 10.1016/j.molimm.2021.11.016, PubMed 34906905
  26. Thorgersen EB, Asvall J, Frøysnes IS, Schjalm C, Larsen SG, Dueland S, Andersson Y, Fodstad Ø, Mollnes TE, Flatmark K (2021)
    Increased Local Inflammatory Response to MOC31PE Immunotoxin After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
    Ann Surg Oncol, 28 (9), 5252-5262
    DOI 10.1245/s10434-021-10022-0, PubMed 34019185
  27. Wiker HG, Mollnes TE, Garred P, Bjune G, Bjorvatn B (2021)
    Morten Harboe (1929-2021), one of the founders of Scandinavian Journal of Immunology OBITUARY
    Scand. J. Immunol., 94 (1), e13054
    DOI 10.1111/sji.13054
  28. Witczak BJ, Pischke SE, Reisæter AV, Midtvedt K, Ludviksen JK, Heldal K, Jenssen T, Hartmann A, Åsberg A, Mollnes TE (2021)
    Elevated Terminal C5b-9 Complement Complex 10 Weeks Post Kidney Transplantation Was Associated With Reduced Long-Term Patient and Kidney Graft Survival
    Front Immunol, 12, 738927
    DOI 10.3389/fimmu.2021.738927, PubMed 34759922
  29. Würzner R, Tedesco F, Garred P, Mollnes TE, Truedsson L, Turner MW, Sommarin Y, Wieslander J, Daha MR (2021)
    Memories of Bob Sim-Genius Complementologist and Cheerful Travel Companion
    Viruses, 13 (6)
    DOI 10.3390/v13061068, PubMed 34199701
  30. Zhu GH, Azharuddin M, Islam R, Rahmoune H, Deb S, Kanji U, Das J, Osterrieth J, Aulakh P, Ibrahim-Hashi H, Manchanda R, Nilsson PH, Mollnes TE, Bhattacharyya M, Islam MM, Hinkula J, Slater NKH, Patra HK (2021)
    Innate Immune Invisible Ultrasmall Gold Nanoparticles-Framework for Synthesis and Evaluation
    ACS Appl Mater Interfaces, 13 (20), 23410-23422
    DOI 10.1021/acsami.1c02834, PubMed 33978409

Publications 2020

  1. Berg LK, Goll R, Fagerli E, Ludviksen JK, Fure H, Moen OS, Sørbye SW, Mollnes TE, Florholmen J (2020)
    Intestinal inflammatory profile shows increase in a diversity of biomarkers in irritable bowel syndrome
    Scand J Gastroenterol, 55 (5), 537-542
    DOI 10.1080/00365521.2020.1754455, PubMed 32329383
  2. Chaban V, Clarke GJB, Skandsen T, Islam R, Einarsen CE, Vik A, Damås JK, Mollnes TE, Håberg AK, Pischke SE (2020)
    Systemic Inflammation Persists the First Year after Mild Traumatic Brain Injury: Results from the Prospective Trondheim Mild Traumatic Brain Injury Study
    J Neurotrauma, 37 (19), 2120-2130
    DOI 10.1089/neu.2019.6963, PubMed 32326805
  3. Ehrnström B, Kojen JF, Giambelluca M, Ryan L, Moen SH, Hu Z, Yin H, Mollnes TE, Damås JK, Espevik T, Stenvik J (2020)
    TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria
    J Leukoc Biol, 107 (4), 673-683
    DOI 10.1002/JLB.3A0120-114R, PubMed 32083344
  4. Grinde D, Øverland T, Lima K, Schjalm C, Mollnes TE, Abrahamsen TG (2020)
    Complement Activation in 22q11.2 Deletion Syndrome
    J Clin Immunol, 40 (3), 515-523
    DOI 10.1007/s10875-020-00766-x, PubMed 32152940
  5. Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P et al. (2020)
    Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
    Proc Natl Acad Sci U S A, 117 (40), 25018-25025
    DOI 10.1073/pnas.2010540117, PubMed 32943538
  6. Hovland A, Retterstøl K, Mollnes TE, Halvorsen B, Aukrust P, Lappegård KT (2020)
    Anti-inflammatory effects of non-statin low-density lipoprotein cholesterol-lowering drugs: an unused potential?
    Scand Cardiovasc J, 54 (5), 274-279
    DOI 10.1080/14017431.2020.1775878, PubMed 32500743
  7. Jøntvedt Jørgensen M, Holter JC, Christensen EE, Schjalm C, Tonby K, Pischke SE, Jenum S, Skeie LG, Nur S, Lind A, Opsand H, Enersen TB, Grøndahl R, Hermann A, Dudman S, Muller F, Ueland T, Mollnes TE, Aukrust P, Heggelund L, Holten AR, Dyrhol-Riise AM (2020)
    Increased interleukin-6 and macrophage chemoattractant protein-1 are associated with respiratory failure in COVID-19
    Sci Rep, 10 (1), 21697
    DOI 10.1038/s41598-020-78710-7, PubMed 33303843
  8. Keshari RS, Silasi R, Popescu NI, Regmi G, Chaaban H, Lambris JD, Lupu C, Mollnes TE, Lupu F (2020)
    CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis
    J Thromb Haemost, 19 (2), 429-443
    DOI 10.1111/jth.15162, PubMed 33174372
  9. Lau C, McAdam MB, Bergseth G, Grevys A, Bruun JA, Ludviksen JK, Fure H, Espevik T, Moen A, Andersen JT, Mollnes TE (2020)
    NHDL, a recombinant VL/VH hybrid antibody control for IgG2/4 antibodies
    MAbs, 12 (1), 1686319
    DOI 10.1080/19420862.2019.1686319, PubMed 31671278
  10. Lipcsey M, Tenhunen J, Pischke SE, Kuitunen A, Flaatten H, De Geer L, Sjölin J, Frithiof R, Chew MS, Bendel S, Kawati R, Larsson A, Mollnes TE, Tønnessen TI, Rubertsson S (2020)
    Endotoxin Removal in Septic Shock with the Alteco LPS Adsorber Was Safe But Showed no Benefit Compared to Placebo in the Double-Blind Randomized Controlled Trial-the Asset Study
    Shock, 54 (2), 224-231
    DOI 10.1097/SHK.0000000000001503, PubMed 31880758
  11. Macpherson ME, Hov JR, Ueland T, Dahl TB, Kummen M, Otterdal K, Holm K, Berge RK, Mollnes TE, Trøseid M, Halvorsen B, Aukrust P, Fevang B, Jørgensen SF (2020)
    Gut Microbiota-Dependent Trimethylamine N-Oxide Associates With Inflammation in Common Variable Immunodeficiency
    Front Immunol, 11, 574500
    DOI 10.3389/fimmu.2020.574500, PubMed 33042155
  12. Mollnes TE, Huber-Lang M (2020)
    Complement in sepsis-when science meets clinics
    FEBS Lett, 594 (16), 2621-2632
    DOI 10.1002/1873-3468.13881, PubMed 32621378
  13. Niyonzima N, Bakke SS, Gregersen I, Holm S, Sandanger Ø, Orrem HL, Sporsheim B, Ryan L, Kong XY, Dahl TB, Skjelland M, Sørensen KK, Rokstad AM, Yndestad A, Latz E, Gullestad L, Andersen GØ, Damås JK, Aukrust P, Mollnes TE, Halvorsen B, Espevik T (2020)
    Cholesterol crystals use complement to increase NLRP3 signaling pathways in coronary and carotid atherosclerosis
    EBioMedicine, 60, 102985
    DOI 10.1016/j.ebiom.2020.102985, PubMed 32927275
  14. Pedersen H, Jensen RK, Jensen JMB, Fox R, Pedersen DV, Olesen HG, Hansen AG, Christiansen D, Mazarakis SMM, Lojek N, Hansen P, Gadeberg TAF, Zarantonello A, Laursen NS, Mollnes TE, Johnson MB, Stevens B, Thiel S, Andersen GR (2020)
    A Complement C3-Specific Nanobody for Modulation of the Alternative Cascade Identifies the C-Terminal Domain of C3b as Functional in C5 Convertase Activity
    J Immunol, 205 (8), 2287-2300
    DOI 10.4049/jimmunol.2000752, PubMed 32938727
  15. Shahini N, Schjalm C, Nilsson PH, Holt MF, Øgaard JDS, Lien E, Ahmed MS, Attramadal H, Aukrust P, Yndestad A, Mollnes TE, Louwe MC (2020)
    Complement component C3 and the TLR co-receptor CD14 are not involved in angiotensin II induced cardiac remodelling
    Biochem Biophys Res Commun, 523 (4), 867-873
    DOI 10.1016/j.bbrc.2020.01.018, PubMed 31955888
  16. Sharifi S, Islam MM, Sharifi H, Islam R, Nilsson PH, Dohlman CH, Mollnes TE, Paschalis EI, Chodosh J (2020)
    Sputter Deposition of Titanium on Poly(Methyl Methacrylate) Enhances Corneal Biocompatibility
    Transl Vis Sci Technol, 9 (13), 41
    DOI 10.1167/tvst.9.13.41, PubMed 33442495
  17. Storjord E, Henno LT, Mollnes TE, Brekke OL (2020)
    Analysis of cytokines
    Tidsskr. Nor. Laegeforen., 140 (1), 71
  18. Storjord E, Hennø LT, Mollnes TE, Brekke OL (2020)
    Analysis of cytokines
    Tidsskr Nor Laegeforen, 140 (1)
    DOI 10.4045/tidsskr.18.0961, PubMed 31948201
  19. Storm BS, Christiansen D, Mollnes TE, Nielsen EW (2020)
    Avoiding ambient air in test tubes during incubations of human whole-blood minimizes complement background activation
    J Immunol Methods, 487, 112876
    DOI 10.1016/j.jim.2020.112876, PubMed 33031792
  20. Ueland NL, Ludvigsen JK, Hellerud BC, Mollnes TE, Skjeflo EW (2020)
    Choice of immunoassay to evaluate porcine cytokine levels
    Vet Immunol Immunopathol, 230, 110129
    DOI 10.1016/j.vetimm.2020.110129, PubMed 33059181
  21. Ueland T, Heggelund L, Lind A, Holten AR, Tonby K, Michelsen AE, Jenum S, Jørgensen MJ, Barratt-Due A, Skeie LG, Nordøy I, Aanensen Fraz MS, Quist-Paulsen E E, Pischke SE, Johal SK, Hesstvedt L, Bogen M, Fevang B, Halvorsen B, Müller F, Bekken GK, Mollnes TE, Dudman S, Aukrust P, Dyrhol-Riise AM et al. (2020)
    Elevated plasma sTIM-3 levels in patients with severe COVID-19
    J Allergy Clin Immunol, 147 (1), 92-98
    DOI 10.1016/j.jaci.2020.09.007, PubMed 32971109
  22. van den Heuvel LP, van de Kar NCAJ, Duineveld C, Sarlea A, van der Velden TJAM, Liebrand WTB, van Kraaij S, Schjalm C, Bouwmeester R, Wetzels JFM, Mollnes TE, Volokhina EB (2020)
    The complement component C5 is not responsible for the alternative pathway activity in rabbit erythrocyte hemolytic assays during eculizumab treatment
    Cell Mol Immunol, 17 (6), 653-655
    DOI 10.1038/s41423-020-0406-y, PubMed 32210393
  23. Zhang J, Song L, Pedersen DV, Li A, Lambris JD, Andersen GR, Mollnes TE, Ma YJ, Garred P (2020)
    Soluble collectin-12 mediates C3-independent docking of properdin that activates the alternative pathway of complement
    Elife, 9
    DOI 10.7554/eLife.60908, PubMed 32909942
  24. Østvik AE, Svendsen TD, Granlund AVB, Doseth B, Skovdahl HK, Bakke I, Thorsvik S, Afroz W, Walaas GA, Mollnes TE, Gustafsson BI, Sandvik AK, Bruland T (2020)
    Intestinal Epithelial Cells Express Immunomodulatory ISG15 During Active Ulcerative Colitis and Crohn's Disease
    J Crohns Colitis, 14 (7), 920-934
    DOI 10.1093/ecco-jcc/jjaa022, PubMed 32020185

Publications 2019

  1. Brekke OL, Christiansen D, Kisserli A, Fure H, Dahl JA, Donvito B, Reveil B, Ludviksen JK, Tabary T, Mollnes TE, Cohen JHM (2019)
    Key role of the number of complement receptor 1 on erythrocytes for binding of Escherichia coli to erythrocytes and for leukocyte phagocytosis and oxidative burst in human whole blood
    Mol Immunol, 114, 139-148
    DOI 10.1016/j.molimm.2019.07.014, PubMed 31352230
  2. Bugge E, Wynn R, Mollnes TE, Reitan SK, Lapid MI, Gronli OK (2019)
    Corrigendum to "Changes in cytokines during treatment of elderly, hospitalized psychiatric patients-A naturalistic study" [Psychoneuroendocrinology, 108C (2019), 135-139]
    Psychoneuroendocrinology, 109, 104427
    DOI 10.1016/j.psyneuen.2019.104427, PubMed 31537376
  3. Bugge E, Wynn R, Mollnes TE, Reitan SK, Lapid MI, Grønli OK (2019)
    Changes in cytokines during treatment of elderly, hospitalized psychiatric patients - a naturalistic study
    Psychoneuroendocrinology, 108, 135-139
    DOI 10.1016/j.psyneuen.2019.06.014, PubMed 31276906
  4. Cedzyński M, Thielens NM, Mollnes TE, Vorup-Jensen T (2019)
    Editorial: The Role of Complement in Health and Disease
    Front Immunol, 10, 1869
    DOI 10.3389/fimmu.2019.01869, PubMed 31440250
  5. Dahm AEA, Jacobsen EM, Wik HS, Jacobsen AF, Mollnes TE, Kanse SM, Sandset PM (2019)
    Elevated Complement C3 and C4 Levels are Associated with Postnatal Pregnancy-Related Venous Thrombosis
    Thromb Haemost, 119 (9), 1481-1488
    DOI 10.1055/s-0039-1692426, PubMed 31254974
  6. Granslo HN, Aarag Fredheim EG, Esaiassen E, Christophersen L, Jensen PØ, Mollnes TE, Moser C, Flaegstad T, Klingenberg C, Cavanagh JP (2019)
    The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model
    APMIS, 127 (6), 475-483
    DOI 10.1111/apm.12946, PubMed 30916807
  7. Gravastrand CS, Steinkjer B, Halvorsen B, Landsem A, Skjelland M, Jacobsen EA, Woodruff TM, Lambris JD, Mollnes TE, Brekke OL, Espevik T, Rokstad AMA (2019)
    Cholesterol Crystals Induce Coagulation Activation through Complement-Dependent Expression of Monocytic Tissue Factor
    J Immunol, 203 (4), 853-863
    DOI 10.4049/jimmunol.1900503, PubMed 31270150
  8. Hagve M, Gjessing PF, Hole MJ, Jansen KM, Fuskevåg OM, Mollnes TE, Larsen TS, Irtun Ø (2019)
    Perioperative Infusion of Glucagon-Like Peptide-1 Prevents Insulin Resistance After Surgical Trauma in Female Pigs
    Endocrinology, 160 (12), 2892-2902
    DOI 10.1210/en.2019-00374, PubMed 31589305
  9. Hardersen R, Enebakk T, Christiansen D, Ludviksen JK, Mollnes TE, Lappegård KT, Hovland A (2019)
    Comparison of cytokine changes in three different lipoprotein apheresis systems in an ex vivo whole blood model
    J Clin Apher, 35 (2), 104-116
    DOI 10.1002/jca.21765, PubMed 31782556
  10. Hokstad I, Deyab G, Wang Fagerland M, Lyberg T, Hjeltnes G, Førre Ø, Agewall S, Mollnes TE, Hollan I (2019)
    Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study
    PLoS One, 14 (7), e0220079
    DOI 10.1371/journal.pone.0220079, PubMed 31335881
  11. Holt MF, Seim BE, Øgaard J, Olsen MB, Woldbæk PR, Kvitting JP, Aukrust P, Yndestad A, Mollnes TE, Nilsson PH, Louwe MC, Ranheim T (2019)
    Selective and marked decrease of complement receptor C5aR2 in human thoracic aortic aneurysms: a dysregulation with potential inflammatory effects
    Open Heart, 6 (2), e001098
    DOI 10.1136/openhrt-2019-001098, PubMed 31798913
  12. Høiland II, Liang RA, Braekkan SK, Pettersen K, Ludviksen JK, Latysheva N, Snir O, Ueland T, Hindberg K, Mollnes TE, Hansen JB (2019)
    Complement activation assessed by the plasma terminal complement complex and future risk of venous thromboembolism
    J Thromb Haemost, 17 (6), 934-943
    DOI 10.1111/jth.14438, PubMed 30920726
  13. Islam MM, Sharifi R, Mamodaly S, Islam R, Nahra D, Abusamra DB, Hui PC, Adibnia Y, Goulamaly M, Paschalis EI, Cruzat A, Kong J, Nilsson PH, Argüeso P, Mollnes TE, Chodosh J, Dohlman CH, Gonzalez-Andrades M (2019)
    Effects of gamma radiation sterilization on the structural and biological properties of decellularized corneal xenografts
    Acta Biomater, 96, 330-344
    DOI 10.1016/j.actbio.2019.07.002, PubMed 31284096
  14. Jørgensen SF, Macpherson ME, Bjørnetrø T, Holm K, Kummen M, Rashidi A, Michelsen AE, Lekva T, Halvorsen B, Trøseid M, Mollnes TE, Berge RK, Yndestad A, Ueland T, Karlsen TH, Aukrust P, Hov JR, Fevang B (2019)
    Rifaximin alters gut microbiota profile, but does not affect systemic inflammation - a randomized controlled trial in common variable immunodeficiency
    Sci Rep, 9 (1), 167 (Retracted)
    DOI 10.1038/s41598-018-35367-7, PubMed 30655568
  15. Kozma GT, Mészáros T, Vashegyi I, Fülöp T, Örfi E, Dézsi L, Rosivall L, Bavli Y, Urbanics R, Mollnes TE, Barenholz Y, Szebeni J (2019)
    Pseudo-anaphylaxis to Polyethylene Glycol (PEG)-Coated Liposomes: Roles of Anti-PEG IgM and Complement Activation in a Porcine Model of Human Infusion Reactions
    ACS Nano, 13 (8), 9315-9324
    DOI 10.1021/acsnano.9b03942, PubMed 31348638
  16. Liang RA, Høiland II, Ueland T, Aukrust P, Snir O, Hindberg K, Braekkan SK, Garred P, Mollnes TE, Hansen JB (2019)
    Plasma levels of mannose-binding lectin and future risk of venous thromboembolism
    J Thromb Haemost, 17 (10), 1661-1669
    DOI 10.1111/jth.14539, PubMed 31220397
  17. Macpherson ME, Halvorsen B, Yndestad A, Ueland T, Mollnes TE, Berge RK, Rashidi A, Otterdal K, Gregersen I, Kong XY, Holven KB, Aukrust P, Fevang B, Jørgensen SF (2019)
    Impaired HDL Function Amplifies Systemic Inflammation in Common Variable Immunodeficiency
    Sci Rep, 9 (1), 9427
    DOI 10.1038/s41598-019-45861-1, PubMed 31263122
  18. Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G, Holers VM, Huber-Lang M, Kinoshita T, Mollnes TE, Montgomery RA, Morgan BP, Nilsson B, Pio R, Ricklin D, Risitano AM, Taylor RP, Mantovani A, Ioannidis JPA, Lambris JD (2019)
    'Stealth' corporate innovation: an emerging threat for therapeutic drug development
    Nat Immunol, 20 (11), 1409-1413
    DOI 10.1038/s41590-019-0503-1, PubMed 31562490
  19. Mastellos DC, Blom AM, Connolly ES, Daha MR, Geisbrecht BV, Ghebrehiwet B, Gros P, Hajishengallis G, Holers VM, Huber-Lang M, Kinoshita T, Mollnes TE, Montgomery RA, Morgan BP, Nilsson B, Pio R, Ricklin D, Risitano AM, Taylor RP, Mantovani A, Ioannidis JPA, Lambris JD (2019)
    Author Correction: 'Stealth' corporate innovation: an emerging threat for therapeutic drug development
    Nat Immunol, 20 (11), 1556
    DOI 10.1038/s41590-019-0531-x, PubMed 31605100
  20. Ottestad W, Rognes IN, Pischke SE, Mollnes TE, Andersson U, Eken T (2019)
    Biphasic Release of the Alarmin High Mobility Group Box 1 Protein Early After Trauma Predicts Poor Clinical Outcome
    Crit Care Med, 47 (8), e614-e622
    DOI 10.1097/CCM.0000000000003800, PubMed 31162203
  21. Pischke SE, Hestenes S, Johansen HT, Fure H, Bugge JF, Espinoza A, Skulstad H, Edvardsen T, Fosse E, Mollnes TE, Halvorsen PS, Nielsen EW (2019)
    Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model
    PLoS One, 14 (6), e0218624
    DOI 10.1371/journal.pone.0218624, PubMed 31247004
  22. Shahini N, Ueland T, Auensen A, Michelsen AE, Ludviksen JK, Hussain AI, Pettersen KI, Aakhus S, Espeland T, Lunde IG, Kirschfink M, Nilsson PH, Mollnes TE, Gullestad L, Aukrust P, Yndestad A, Louwe MC (2019)
    Increased Complement Factor B and Bb Levels Are Associated with Mortality in Patients with Severe Aortic Stenosis
    J Immunol, 203 (7), 1973-1980
    DOI 10.4049/jimmunol.1801244, PubMed 31492744
  23. Siljan WW, Holter JC, Michelsen AE, Nymo SH, Lauritzen T, Oppen K, Husebye E, Ueland T, Mollnes TE, Aukrust P, Heggelund L (2019)
    Inflammatory biomarkers are associated with aetiology and predict outcomes in community-acquired pneumonia: results of a 5-year follow-up cohort study
    ERJ Open Res, 5 (1)
    DOI 10.1183/23120541.00014-2019, PubMed 30863773
  24. Skjeflo EW, Christiansen D, Landsem A, Stenvik J, Woodruff TM, Espevik T, Nielsen EW, Mollnes TE (2019)
    Phagocytosis of live and dead Escherichia coli and Staphylococcus aureus in human whole blood is markedly reduced by combined inhibition of C5aR1 and CD14
    Mol Immunol, 112, 131-139
    DOI 10.1016/j.molimm.2019.03.014, PubMed 31102985
  25. Thomas AM, Gerogianni A, McAdam MB, Fløisand Y, Lau C, Espevik T, Nilsson PH, Mollnes TE, Barratt-Due A (2019)
    Complement Component C5 and TLR Molecule CD14 Mediate Heme-Induced Thromboinflammation in Human Blood
    J Immunol, 203 (6), 1571-1578
    DOI 10.4049/jimmunol.1900047, PubMed 31413105
  26. Thorgersen EB, Barratt-Due A, Haugaa H, Harboe M, Pischke SE, Nilsson PH, Mollnes TE (2019)
    The Role of Complement in Liver Injury, Regeneration, and Transplantation
    Hepatology, 70 (2), 725-736
    DOI 10.1002/hep.30508, PubMed 30653682

Publications 2018

  1. Askarian F, Lapek JD, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M (2018)
    Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models
    Front Microbiol, 9, 262
    DOI 10.3389/fmicb.2018.00262, PubMed 29515544
  2. Bjerre A, Bergseth G, Ludviksen JK, Stokke A, Bosnes V, Karpman D, Mollnes TE (2018)
    Clinical and Complement Long-Term Follow-Up of a Pediatric Patient with C3 Mutation-Related Atypical Hemolytic Uremic Syndrome
    Case Rep Nephrol, 2018, 3810249
    DOI 10.1155/2018/3810249, PubMed 30662780
  3. Bugge E, Wynn R, Mollnes TE, Reitan SK, Grønli OK (2018)
    Cytokine profiles and diagnoses in elderly, hospitalized psychiatric patients
    BMC Psychiatry, 18 (1), 315
    DOI 10.1186/s12888-018-1900-y, PubMed 30261848
  4. Gaya da Costa M, Poppelaars F, van Kooten C, Mollnes TE, Tedesco F, Würzner R, Trouw LA, Truedsson L, Daha MR, Roos A, Seelen MA (2018)
    Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population
    Front Immunol, 9, 2664
    DOI 10.3389/fimmu.2018.02664, PubMed 30515158
  5. Gaarden TL, Engedal K, Benth JŠ, Larsen M, Lorentzen B, Mollnes TE, Bjølseth TM, Castellheim A (2018)
    Exploration of 27 plasma immune markers: a cross-sectional comparison of 64 old psychiatric inpatients having unipolar major depression and 18 non-depressed old persons
    BMC Geriatr, 18 (1), 149
    DOI 10.1186/s12877-018-0836-x, PubMed 29940870
  6. Habberstad R, Frøseth TCS, Aass N, Abramova T, Baas T, Mørkeset ST, Caraceni A, Laird B, Boland JW, Rossi R, Garcia-Alonso E, Stensheim H, Loge JH, Hjermstad MJ, Bjerkeset E, Bye A, Lund JÅ, Solheim TS, Vagnildhaug OM, Brunelli C, Damås JK, Mollnes TE, Kaasa S, Klepstad P (2018)
    The Palliative Radiotherapy and Inflammation Study (PRAIS) - protocol for a longitudinal observational multicenter study on patients with cancer induced bone pain
    BMC Palliat Care, 17 (1), 110
    DOI 10.1186/s12904-018-0362-9, PubMed 30266081
  7. Hardersen R, Enebakk T, Christiansen D, Bergseth G, Brekke OL, Mollnes TE, Lappegård KT, Hovland A (2018)
    Granulocyte and monocyte CD11b expression during plasma separation is dependent on complement factor 5 (C5) - an ex vivo study with blood from a C5-deficient individual
    APMIS, 126 (4), 342-352
    DOI 10.1111/apm.12821, PubMed 29575196
  8. Høiland II, Liang RA, Hindberg K, Latysheva N, Brekke OL, Mollnes TE, Hansen JB (2018)
    Associations between complement pathways activity, mannose-binding lectin, and odds of unprovoked venous thromboembolism
    Thromb Res, 169, 50-56
    DOI 10.1016/j.thromres.2018.06.019, PubMed 30015228
  9. Kleveland O, Ueland T, Kunszt G, Bratlie M, Yndestad A, Broch K, Holte E, Ryan L, Amundsen BH, Bendz B, Aakhus S, Espevik T, Halvorsen B, Mollnes TE, Wiseth R, Gullestad L, Aukrust P, Damås JK (2018)
    Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction
    Int J Cardiol, 271, 1-7
    DOI 10.1016/j.ijcard.2018.04.136, PubMed 29961572
  10. Landsem A, Fure H, Krey Ludviksen J, Christiansen D, Lau C, Mathisen M, Bergseth G, Nymo S, Lappegård KT, Woodruff TM, Espevik T, Mollnes TE, Brekke OL (2018)
    Complement component 5 does not interfere with physiological hemostasis but is essential for Escherichia coli-induced coagulation accompanied by Toll-like receptor 4
    Clin Exp Immunol, 196 (1), 97-110
    DOI 10.1111/cei.13240, PubMed 30444525
  11. Langeland H, Bergum D, Løberg M, Bjørnstad K, Damås JK, Mollnes TE, Skjærvold NK, Klepstad P (2018)
    Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study
    JMIR Res Protoc, 7 (1), e17
    DOI 10.2196/resprot.8558, PubMed 29351897
  12. Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE (2018)
    Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
    ESC Heart Fail, 5 (3), 292-301
    DOI 10.1002/ehf2.12266, PubMed 29424484
  13. Orrem HL, Nilsson PH, Pischke SE, Kleveland O, Yndestad A, Ekholt K, Damås JK, Espevik T, Bendz B, Halvorsen B, Gregersen I, Wiseth R, Andersen GØ, Ueland T, Gullestad L, Aukrust P, Barratt-Due A, Mollnes TE (2018)
    IL-6 Receptor Inhibition by Tocilizumab Attenuated Expression of C5a Receptor 1 and 2 in Non-ST-Elevation Myocardial Infarction
    Front Immunol, 9, 2035
    DOI 10.3389/fimmu.2018.02035, PubMed 30258440
  14. Orrem HL, Shetelig C, Ueland T, Limalanathan S, Nilsson PH, Husebye T, Aukrust P, Seljeflot I, Hoffmann P, Eritsland J, Mollnes TE, Andersen GØ, Yndestad A (2018)
    Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction
    Int J Cardiol, 268, 187-192
    DOI 10.1016/j.ijcard.2018.05.032, PubMed 29853279
  15. Quist-Paulsen E, Aukrust P, Kran AB, Dunlop O, Ormaasen V, Stiksrud B, Midttun Ø, Ueland T, Ueland PM, Mollnes TE, Dyrhol-Riise AM (2018)
    High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
    J Neuroinflammation, 15 (1), 327
    DOI 10.1186/s12974-018-1366-3, PubMed 30470234
  16. Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Skattum L, Bosnes V, Garred P, Frøland SS, Mollnes TE, Aukrust P, Heggelund L (2018)
    Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia
    Open Forum Infect Dis, 5 (2), ofy002
    DOI 10.1093/ofid/ofy002, PubMed 29410975
  17. Skjeflo EW, Christiansen D, Fure H, Ludviksen JK, Woodruff TM, Espevik T, Nielsen EW, Brekke OL, Mollnes TE (2018)
    Staphylococcus aureus-induced complement activation promotes tissue factor-mediated coagulation
    J Thromb Haemost, 16 (5), 905-918
    DOI 10.1111/jth.13979, PubMed 29437288
  18. Skovdahl HK, Damås JK, Granlund AVB, Østvik AE, Doseth B, Bruland T, Mollnes TE, Sandvik AK (2018)
    C-C Motif Ligand 20 (CCL20) and C-C Motif Chemokine Receptor 6 (CCR6) in Human Peripheral Blood Mononuclear Cells: Dysregulated in Ulcerative Colitis and a Potential Role for CCL20 in IL-1β Release
    Int J Mol Sci, 19 (10)
    DOI 10.3390/ijms19103257, PubMed 30347808
  19. Skaare H, Svensson M, Jenssen T, Åsberg A, Schmidt EB, Chandra A, Ueland T, Mollnes TE, Hartmann A, Eide IA (2018)
    Plasma n-6 Polyunsaturated Fatty Acid Levels and Survival in Renal Transplantation
    J Ren Nutr, 28 (5), 333-339
    DOI 10.1053/j.jrn.2018.02.008, PubMed 29703632
  20. Thomas AM, Schjalm C, Nilsson PH, Lindenskov PHH, Rørtveit R, Solberg R, Saugstad OD, Berglund MM, Strömberg P, Lau C, Espevik T, Jansen JH, Castellheim A, Mollnes TE, Barratt-Due A (2018)
    Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome
    Neonatology, 113 (4), 322-330
    DOI 10.1159/000486542, PubMed 29486477
  21. Wendelbo Ø, Opheim EN, Hervig T, Felli Lunde TH, Bruserud Ø, Mollnes TE, Reikvam H (2018)
    Cytokine profiling and post-transfusion haemoglobin increment in patients with haematological diseases
    Vox Sang, 113 (7), 657-668
    DOI 10.1111/vox.12703, PubMed 30159896
  22. Wolf-Grosse S, Mollnes TE, Ali S, Stenvik J, Nilsen AM (2018)
    Iron oxide nanoparticles enhance Toll-like receptor-induced cytokines in a particle size- and actin-dependent manner in human blood
    Nanomedicine (Lond), 13 (14), 1773-1785
    DOI 10.2217/nnm-2017-0362, PubMed 30084726

Publications 2017

  1. Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T (2017)
    Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
    J Immunol, 199 (8), 2910-2920
    DOI 10.4049/jimmunol.1700302, PubMed 28855312
  2. Fiane KKH, Dahle G, Bendz B, Halvorsen PS, Abdelnoor M, Mollnes TE, Fosse E (2017)
    Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement
    Scand Cardiovasc J, 52 (1), 43-50
    DOI 10.1080/14017431.2017.1416157, PubMed 29233022
  3. Gravastrand C, Hamad S, Fure H, Steinkjer B, Ryan L, Oberholzer J, Lambris JD, Lacík I, Mollnes TE, Espevik T, Brekke OL, Rokstad AM (2017)
    Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII
    Acta Biomater, 58, 158-167
    DOI 10.1016/j.actbio.2017.05.052, PubMed 28576714
  4. Gustavsen A, Skattum L, Bergseth G, Lorentzen B, Floisand Y, Bosnes V, Mollnes TE, Barratt-Due A (2017)
    Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report
    Medicine (Baltimore), 96 (11), e6338
    DOI 10.1097/MD.0000000000006338, PubMed 28296762
  5. Harboe M, Johnson C, Nymo S, Ekholt K, Schjalm C, Lindstad JK, Pharo A, Hellerud BC, Nilsson Ekdahl K, Mollnes TE, Nilsson PH (2017)
    Properdin binding to complement activating surfaces depends on initial C3b deposition
    Proc Natl Acad Sci U S A, 114 (4), E534-E539
    DOI 10.1073/pnas.1612385114, PubMed 28069958
  6. Hellerud BC, Orrem HL, Dybwik K, Pischke SE, Baratt-Due A, Castellheim A, Fure H, Bergseth G, Christiansen D, Nunn MA, Espevik T, Lau C, Brandtzæg P, Nielsen EW, Mollnes TE (2017)
    Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis
    J Intensive Care, 5, 21
    DOI 10.1186/s40560-017-0217-0, PubMed 28261486
  7. Hennø LT, Storjord E, Christiansen D, Bergseth G, Ludviksen JK, Fure H, Barene S, Nielsen EW, Mollnes TE, Brekke OL (2017)
    Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines - Consequences for defining reference values in healthy humans
    Cytokine, 97, 86-95
    DOI 10.1016/j.cyto.2017.05.014, PubMed 28595117
  8. Keshari RS, Silasi R, Popescu NI, Patel MM, Chaaban H, Lupu C, Coggeshall KM, Mollnes TE, DeMarco SJ, Lupu F (2017)
    Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis
    Proc Natl Acad Sci U S A, 114 (31), E6390-E6399
    DOI 10.1073/pnas.1706818114, PubMed 28720697
  9. Nilsson PH, Thomas AM, Bergseth G, Gustavsen A, Volokhina EB, van den Heuvel LP, Barratt-Due A, Mollnes TE (2017)
    Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses
    Mol Immunol, 89, 111-114
    DOI 10.1016/j.molimm.2017.05.021, PubMed 28610663
  10. Paunas TIF, Finne K, Leh S, Marti HP, Mollnes TE, Berven F, Vikse BE (2017)
    Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy
    Clin Proteomics, 14, 30
    DOI 10.1186/s12014-017-9165-x, PubMed 28814945
  11. Pischke SE, Gustavsen A, Orrem HL, Egge KH, Courivaud F, Fontenelle H, Despont A, Bongoni AK, Rieben R, Tønnessen TI, Nunn MA, Scott H, Skulstad H, Barratt-Due A, Mollnes TE (2017)
    Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function
    Basic Res Cardiol, 112 (3), 20
    DOI 10.1007/s00395-017-0610-9, PubMed 28258298
  12. Ricklin D, Barratt-Due A, Mollnes TE (2017)
    Complement in clinical medicine: Clinical trials, case reports and therapy monitoring
    Mol Immunol, 89, 10-21
    DOI 10.1016/j.molimm.2017.05.013, PubMed 28576323
  13. Shahini N, Michelsen AE, Nilsson PH, Ekholt K, Gullestad L, Broch K, Dahl CP, Aukrust P, Ueland T, Mollnes TE, Yndestad A, Louwe MC (2017)
    The alternative complement pathway is dysregulated in patients with chronic heart failure
    Sci Rep, 7, 42532
    DOI 10.1038/srep42532, PubMed 28195242
  14. Shields KJ, Mollnes TE, Eidet JR, Mikkelsen K, Almdahl SM, Bottazzi B, Lyberg T, Manzi S, Ahearn JM, Hollan I (2017)
    Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases
    PLoS One, 12 (3), e0174577
    DOI 10.1371/journal.pone.0174577, PubMed 28362874
  15. Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Aukrust P, Mollnes TE, Heggelund L (2017)
    Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia
    Eur J Clin Invest, 48 (1)
    DOI 10.1111/eci.12865, PubMed 29171871
  16. Wibroe PP, Anselmo AC, Nilsson PH, Sarode A, Gupta V, Urbanics R, Szebeni J, Hunter AC, Mitragotri S, Mollnes TE, Moghimi SM (2017)
    Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes
    Nat Nanotechnol, 12 (6), 589-594
    DOI 10.1038/nnano.2017.47, PubMed 28396605
  17. Wolf-Grosse S, Rokstad AM, Ali S, Lambris JD, Mollnes TE, Nilsen AM, Stenvik J (2017)
    Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model
    Int J Nanomedicine, 12, 3927-3940
    DOI 10.2147/IJN.S136453, PubMed 28579778
  18. Wyller VB, Nguyen CB, Ludviksen JA, Mollnes TE (2017)
    Transforming growth factor beta (TGF-β) in adolescent chronic fatigue syndrome
    J Transl Med, 15 (1), 245
    DOI 10.1186/s12967-017-1350-1, PubMed 29202780

Publications 2016

  1. Aresvik DM, Lima K, Øverland T, Mollnes TE, Abrahamsen TG (2016)
    Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome
    Scand J Immunol, 83 (3), 188-94
    DOI 10.1111/sji.12406, PubMed 26708691
  2. Barratt-Due A, Fløisand Y, Orrem HL, Kvam AK, Holme PA, Bergseth G, Tjønnfjord GE, Mollnes TE (2016)
    Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome
    Rheumatology (Oxford), 55 (7), 1337-9
    DOI 10.1093/rheumatology/kew040, PubMed 27105662
  3. Barratt-Due A, Pischke SE, Nilsson PH, Espevik T, Mollnes TE (2016)
    Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets
    J Leukoc Biol, 101 (1), 193-204
    DOI 10.1189/jlb.3VMR0316-132R, PubMed 27581539
  4. Eide IA, Åsberg A, Svensson M, Ueland T, Mollnes TE, Hartmann A, Bjerve KS, Michelsen A, Aukrust P, Christensen JH, Schmidt EB, Jenssen T (2016)
    Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients
    J Ren Nutr, 27 (3), 161-168
    DOI 10.1053/j.jrn.2016.09.008, PubMed 27838193
  5. Garabet L, Gilboe IM, Mowinckel MC, Jacobsen AF, Mollnes TE, Sandset PM, Jacobsen EM (2016)
    Antiphospholipid Antibodies are Associated with Low Levels of Complement C3 and C4 in Patients with Systemic Lupus Erythematosus
    Scand J Immunol, 84 (2), 95-9
    DOI 10.1111/sji.12445, PubMed 27135178
  6. Gustavsen A, Nymo S, Landsem A, Christiansen D, Ryan L, Husebye H, Lau C, Pischke SE, Lambris JD, Espevik T, Mollnes TE (2016)
    Combined Inhibition of Complement and CD14 Attenuates Bacteria-Induced Inflammation in Human Whole Blood More Efficiently Than Antagonizing the Toll-like Receptor 4-MD2 Complex
    J Infect Dis, 214 (1), 140-50
    DOI 10.1093/infdis/jiw100, PubMed 26977050
  7. Hestad KA, Engedal K, Whist JE, Aukrust P, Farup PG, Mollnes TE, Ueland T (2016)
    Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis
    Neuropsychiatr Dis Treat, 12, 817-22
    DOI 10.2147/NDT.S101925, PubMed 27110115
  8. Jørgensen SF, Trøseid M, Kummen M, Anmarkrud JA, Michelsen AE, Osnes LT, Holm K, Høivik ML, Rashidi A, Dahl CP, Vesterhus M, Halvorsen B, Mollnes TE, Berge RK, Moum B, Lundin KE, Fevang B, Ueland T, Karlsen TH, Aukrust P, Hov JR (2016)
    Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
    Mucosal Immunol, 9 (6), 1455-1465
    DOI 10.1038/mi.2016.18, PubMed 26982597
  9. Landsem A, Fure H, Mollnes TE, Nielsen EW, Brekke OL (2016)
    C1-inhibitor efficiently delays clot development in normal human whole blood and inhibits Escherichia coli-induced coagulation measured by thromboelastometry
    Thromb Res, 143, 63-70
    DOI 10.1016/j.thromres.2016.04.024, PubMed 27197075
  10. Lappegård KT, Enebakk T, Thunhaug H, Ludviksen JK, Mollnes TE, Hovland A (2016)
    LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition with evolocumab induces no inflammatory response
    J Clin Lipidol, 10 (6), 1481-1487
    DOI 10.1016/j.jacl.2016.09.001, PubMed 27919366
  11. Niyonzima N, Halvorsen B, Sporsheim B, Garred P, Aukrust P, Mollnes TE, Espevik T (2016)
    Complement activation by cholesterol crystals triggers a subsequent cytokine response
    Mol Immunol, 84, 43-50
    DOI 10.1016/j.molimm.2016.09.019, PubMed 27692470
  12. Nymo S, Gustavsen A, Nilsson PH, Lau C, Espevik T, Mollnes TE (2016)
    Human Endothelial Cell Activation by Escherichia coli and Staphylococcus aureus Is Mediated by TNF and IL-1β Secondarily to Activation of C5 and CD14 in Whole Blood
    J Immunol, 196 (5), 2293-9
    DOI 10.4049/jimmunol.1502220, PubMed 26800874
  13. Otterdal K, Portillo A, Astrup E, Ludviksen J, Davì G, Holm S, Santilli F, Vitale G, Raoult D, Olano JP, Schjalm C, Halvorsen B, Oteo JA, Mollnes TE, Aukrust P, Nilsson PH (2016)
    High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation
    Cytokine, 83, 269-274
    DOI 10.1016/j.cyto.2016.05.006, PubMed 27180202
  14. Otterdal K, Portillo A, Astrup E, Ludviksen JK, Schjalm C, Raoult D, Olano JP, Halvorsen B, Oteo JA, Aukrust P, Mollnes TE, Nilsson PH (2016)
    Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo
    Clin Microbiol Infect, 22 (8), 734.e1-6
    DOI 10.1016/j.cmi.2016.05.010, PubMed 27217049
  15. Pilely K, Rosbjerg A, Genster N, Gal P, Pál G, Halvorsen B, Holm S, Aukrust P, Bakke SS, Sporsheim B, Nervik I, Niyonzima N, Bartels ED, Stahl GL, Mollnes TE, Espevik T, Garred P (2016)
    Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis
    J Immunol, 196 (12), 5064-74
    DOI 10.4049/jimmunol.1502595, PubMed 27183610
  16. Siljan WW, Holter JC, Nymo SH, Schjalm C, Müller F, Jenum PA, Husebye E, Ueland T, Aukrust P, Mollnes TE, Heggelund L (2016)
    Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome
    J Infect, 73 (4), 383-6
    DOI 10.1016/j.jinf.2016.07.011, PubMed 27452197
  17. Smedbråten J, Mjøen G, Hartmann A, Åsberg A, Rollag H, Mollnes TE, Sandvik L, Fagerland MW, Thiel S, Sagedal S (2016)
    Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients
    BMC Nephrol, 17 (1), 148
    DOI 10.1186/s12882-016-0373-9, PubMed 27760523
  18. Smedbråten J, Sagedal S, Åsberg A, Hartmann A, Rollag H, Mjøen G, Fagerland MW, Hansen SW, Mollnes TE, Thiel S (2016)
    Collectin Liver 1 and Collectin Kidney 1 of the Lectin Complement Pathway Are Associated With Mortality After Kidney Transplantation
    Am J Transplant, 17 (1), 265-271
    DOI 10.1111/ajt.13933, PubMed 27341702
  19. Stiksrud B, Lorvik KB, Kvale D, Mollnes TE, Ueland PM, Trøseid M, Taskén K, Dyrhol-Riise AM (2016)
    Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts
    J Acquir Immune Defic Syndr, 73 (2), 138-48
    DOI 10.1097/QAI.0000000000001080, PubMed 27632144
  20. Storjord E, Dahl JA, Landsem A, Fure H, Ludviksen JK, Goldbeck-Wood S, Karlsen BO, Berg KS, Mollnes TE, W Nielsen E, Brekke OL (2016)
    Systemic inflammation in acute intermittent porphyria: a case-control study
    Clin Exp Immunol, 187 (3), 466-479
    DOI 10.1111/cei.12899, PubMed 27859020
  21. Stylianou E, Ueland T, Borchsenius F, Michelsen AE, Øvstebø R, Mollnes TE, Skjønsberg OH, Aukrust P (2016)
    Specific allergen immunotherapy: effect on IgE, IgG4 and chemokines in patients with allergic rhinitis
    Scand J Clin Lab Invest, 76 (2), 118-27
    DOI 10.3109/00365513.2015.1110856, PubMed 26878875
  22. Ørning P, Hoem KS, Coron AE, Skjåk-Bræk G, Mollnes TE, Brekke OL, Espevik T, Rokstad AM (2016)
    Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation
    J Control Release, 229, 58-69
    DOI 10.1016/j.jconrel.2016.03.021, PubMed 26993426

Publications 2015

  1. Asprusten TT, Fagermoen E, Sulheim D, Skovlund E, Sørensen Ø, Mollnes TE, Wyller VB (2015)
    Study findings challenge the content validity of the Canadian Consensus Criteria for adolescent chronic fatigue syndrome
    Acta Paediatr, 104 (5), 498-503
    DOI 10.1111/apa.12950, PubMed 25640602
  2. Berg A, Otterdal K, Patel S, Gonca M, David C, Dalen I, Nymo S, Nilsson M, Nordling S, Magnusson PU, Ueland T, Prato M, Giribaldi G, Mollnes TE, Aukrust P, Langeland N, Nilsson PH (2015)
    Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria
    J Infect Dis, 212 (11), 1835-40
    DOI 10.1093/infdis/jiv283, PubMed 25980034
  3. Bergstrøm B, Aune MH, Awuh JA, Kojen JF, Blix KJ, Ryan L, Flo TH, Mollnes TE, Espevik T, Stenvik J (2015)
    TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling Pathway
    J Immunol, 195 (3), 1100-11
    DOI 10.4049/jimmunol.1403176, PubMed 26085680
  4. Blom AM, Österborg A, Mollnes TE, Okroj M (2015)
    Antibodies reactive to cleaved sites in complement proteins enable highly specific measurement of soluble markers of complement activation
    Mol Immunol, 66 (2), 164-70
    DOI 10.1016/j.molimm.2015.02.029, PubMed 25795308
  5. Egge KH, Barratt-Due A, Nymo S, Lindstad JK, Pharo A, Lau C, Espevik T, Thorgersen EB, Mollnes TE (2015)
    The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load
    Clin Exp Immunol, 181 (3), 457-67
    DOI 10.1111/cei.12645, PubMed 25907631
  6. Egge KH, Thorgersen EB, Pischke SE, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn MA, Barratt-Due A, Mollnes TE (2015)
    Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14
    Immunobiology, 220 (8), 999-1005
    DOI 10.1016/j.imbio.2015.04.002, PubMed 25956456
  7. Fretland AA, Sokolov A, Postriganova N, Kazaryan AM, Pischke SE, Nilsson PH, Rognes IN, Bjornbeth BA, Fagerland MW, Mollnes TE, Edwin B (2015)
    Inflammatory Response After Laparoscopic Versus Open Resection of Colorectal Liver Metastases: Data From the Oslo-CoMet Trial
    Medicine (Baltimore), 94 (42), e1786
    DOI 10.1097/MD.0000000000001786, PubMed 26496309
  8. Hein E, Munthe-Fog L, Thiara AS, Fiane AE, Mollnes TE, Garred P (2015)
    Heparin-coated cardiopulmonary bypass circuits selectively deplete the pattern recognition molecule ficolin-2 of the lectin complement pathway in vivo
    Clin Exp Immunol, 179 (2), 294-9
    DOI 10.1111/cei.12446, PubMed 25174443
  9. Hellerud BC, Olstad OK, Nielsen EW, Trøseid AM, Skadberg Ø, Thorgersen EB, Vege Å, Mollnes TE, Brandtzæg P (2015)
    Massive Organ Inflammation in Experimental and in Clinical Meningococcal Septic Shock
    Shock, 44 (5), 458-69
    DOI 10.1097/SHK.0000000000000441, PubMed 26473439
  10. Hovland A, Jonasson L, Garred P, Yndestad A, Aukrust P, Lappegård KT, Espevik T, Mollnes TE (2015)
    The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis
    Atherosclerosis, 241 (2), 480-94
    DOI 10.1016/j.atherosclerosis.2015.05.038, PubMed 26086357
  11. Huang S, Engberg AE, Jonsson N, Sandholm K, Nicholls IA, Mollnes TE, Fromell K, Nilsson B, Ekdahl KN (2015)
    Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood
    Biomaterials, 77, 111-9
    DOI 10.1016/j.biomaterials.2015.10.067, PubMed 26584351
  12. Haakonsen Lindenskov PH, Castellheim A, Saugstad OD, Mollnes TE (2015)
    Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies
    Neonatology, 107 (3), 225-230
    DOI 10.1159/000369373, PubMed 25721501
  13. Khan F, Pharo A, Lindstad JK, Mollnes TE, Tønnessen TI, Pischke SE (2015)
    Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis
    Scand J Immunol, 82 (5), 467-75
    DOI 10.1111/sji.12332, PubMed 26099791
  14. Landsem A, Fure H, Christiansen D, Nielsen EW, Østerud B, Mollnes TE, Brekke OL (2015)
    The key roles of complement and tissue factor in Escherichia coli-induced coagulation in human whole blood
    Clin Exp Immunol, 182 (1), 81-9
    DOI 10.1111/cei.12663, PubMed 26241501
  15. Lappegård KT, Bjerre A, Tjønnfjord GE, Mollnes TE (2015)
    Therapeutic complement inhibition – from experimental to clinical medicine
    Tidsskr Nor Laegeforen, 135 (19), 1745-9
    DOI 10.4045/tidsskr.15.0049, PubMed 26486669
  16. Lappegård KT, Bjørnstad H, Mollnes TE, Hovland A (2015)
    Effect of Cardiac Resynchronization Therapy on Inflammation in Congestive Heart Failure: A Review
    Scand J Immunol, 82 (3), 191-8
    DOI 10.1111/sji.12328, PubMed 26099323
  17. Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
    PLoS One, 10 (2), e0117261
    DOI 10.1371/journal.pone.0117261, PubMed 25706641
  18. Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
    Genom Data, 5, 176-83
    DOI 10.1016/j.gdata.2015.05.019, PubMed 26484252
  19. Meroni PL, Macor P, Durigutto P, De Maso L, Gerosa M, Ferraresso M, Borghi MO, Mollnes TE, Tedesco F (2015)
    Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery
    Blood, 127 (3), 365-7
    DOI 10.1182/blood-2015-09-672139, PubMed 26644452
  20. Neupane SP, Lien L, Ueland T, Mollnes TE, Aukrust P, Bramness JG (2015)
    Serum brain-derived neurotrophic factor levels in relation to comorbid depression and cytokine levels in Nepalese men with alcohol-use disorders
    Alcohol, 49 (5), 471-8
    DOI 10.1016/j.alcohol.2015.01.012, PubMed 25873205
  21. Nilsson B, Ekdahl KN, Kemper C, Mollnes TE (2015)
    Preface. 15th European Meeting on Complement in Human Disease 2015, Uppsala, Sweden
    Mol Immunol, 67 (1), 1-2
    DOI 10.1016/j.molimm.2015.04.006, PubMed 25934434
  22. Niyonzima N, Samstad EO, Aune MH, Ryan L, Bakke SS, Rokstad AM, Wright SD, Damås JK, Mollnes TE, Latz E, Espevik T (2015)
    Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation
    J Immunol, 195 (1), 257-64
    DOI 10.4049/jimmunol.1403044, PubMed 26026058
  23. Prebensen C, Ueland T, Michelsen AE, Lind A, Pettersen FO, Mollnes TE, Aukrust P, Dyrhol-Riise AM, Kvale D (2015)
    High MIP-1β Levels in Plasma Predict Long-Term Immunological Nonresponse to Suppressive Antiretroviral Therapy in HIV Infection
    J Acquir Immune Defic Syndr, 69 (4), 395-402
    DOI 10.1097/QAI.0000000000000617, PubMed 26115437
  24. Skjeflo EW, Sagatun C, Dybwik K, Aam S, Urving SH, Nunn MA, Fure H, Lau C, Brekke OL, Huber-Lang M, Espevik T, Barratt-Due A, Nielsen EW, Mollnes TE (2015)
    Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis
    Crit Care, 19, 415
    DOI 10.1186/s13054-015-1129-9, PubMed 26612199
  25. Smedbråten YV, Sagedal S, Mjøen G, Hartmann A, Fagerland MW, Rollag H, Mollnes TE, Thiel S (2015)
    High ficolin-3 level at the time of transplantation is an independent risk factor for graft loss in kidney transplant recipients
    Transplantation, 99 (4), 791-6
    DOI 10.1097/TP.0000000000000422, PubMed 25222012
  26. Volokhina EB, Bergseth G, van de Kar NC, van den Heuvel LP, Mollnes TE (2015)
    Eculizumab treatment efficiently prevents C5 cleavage without C5a generation in vivo
    Blood, 126 (2), 278-9
    DOI 10.1182/blood-2015-03-637645, PubMed 26160188
  27. Volokhina EB, van de Kar NC, Bergseth G, van der Velden TJ, Westra D, Wetzels JF, van den Heuvel LP, Mollnes TE (2015)
    Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome
    Clin Immunol, 160 (2), 237-43
    DOI 10.1016/j.clim.2015.05.018, PubMed 26111482
  28. Volokhina EB, Westra D, van der Velden TJ, van de Kar NC, Mollnes TE, van den Heuvel LP (2015)
    Complement activation patterns in atypical haemolytic uraemic syndrome during acute phase and in remission
    Clin Exp Immunol, 181 (2), 306-13
    DOI 10.1111/cei.12426, PubMed 25079699
  29. Wergeland I, Pullar N, Assmus J, Ueland T, Tonby K, Feruglio S, Kvale D, Damås JK, Aukrust P, Mollnes TE, Dyrhol-Riise AM (2015)
    IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy
    J Infect, 70 (4), 381-91
    DOI 10.1016/j.jinf.2014.12.019, PubMed 25597826
  30. Wyller VB, Reme SE, Mollnes TE (2015)
    Chronic fatigue syndrome/myalgic encephalo-myelitis--pathophysiology, diagnosis and treatment
    Tidsskr Nor Laegeforen, 135 (23-24), 2172-5
    DOI 10.4045/tidsskr.15.1180, PubMed 26674040
  31. Würzner R, Tedesco F, Garred P, Mollnes TE, Truedsson L, Turner MW, Sommarin Y, Wieslander J, Sim RB (2015)
    European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager: Mohamed R. Daha
    Mol Immunol, 68 (1), 63-6
    DOI 10.1016/j.molimm.2015.05.003, PubMed 26006049

Publications 2014

  1. Berg A, Patel S, Gonca M, David C, Otterdal K, Ueland T, Dalen I, Kvaløy JT, Mollnes TE, Aukrust P, Langeland N (2014)
    Cytokine network in adults with falciparum Malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity
    PLoS One, 9 (12), e114480
    DOI 10.1371/journal.pone.0114480, PubMed 25503583
  2. Bergseth G, Ludviksen JK, Kirschfink M, Giclas PC, Nilsson B, Mollnes TE (2014)
    An international serum standard for application in assays to detect human complement activation products (vol 56, pg 232, 2013)
    Mol. Immunol., 60 (2), 115
    DOI 10.1016/j.molimm.2014.04.008
  3. Bisschops LL, van der Hoeven JG, Mollnes TE, Hoedemaekers CW (2014)
    Seventy-two hours of mild hypothermia after cardiac arrest is associated with a lowered inflammatory response during rewarming in a prospective observational study
    Crit Care, 18 (5), 546
    DOI 10.1186/s13054-014-0546-5, PubMed 25304549
  4. Blom AM, Volokhina EB, Fransson V, Strömberg P, Berghard L, Viktorelius M, Mollnes TE, López-Trascasa M, van den Heuvel LP, Goodship TH, Marchbank KJ, Okroj M (2014)
    A novel method for direct measurement of complement convertases activity in human serum
    Clin Exp Immunol, 178 (1), 142-53
    DOI 10.1111/cei.12388, PubMed 24853370
  5. Engberg AE, Nilsson PH, Huang S, Fromell K, Hamad OA, Mollnes TE, Rosengren-Holmberg JP, Sandholm K, Teramura Y, Nicholls IA, Nilsson B, Ekdahl KN (2014)
    Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma
    Biomaterials, 36, 55-65
    DOI 10.1016/j.biomaterials.2014.09.011, PubMed 25292422
  6. Hallstensen RF, Bergseth G, Foss S, Jæger S, Gedde-Dahl T, Holt J, Christiansen D, Lau C, Brekke OL, Armstrong E, Stefanovic V, Andersen JT, Sandlie I, Mollnes TE (2014)
    Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn
    Immunobiology, 220 (4), 452-9
    DOI 10.1016/j.imbio.2014.11.003, PubMed 25468724
  7. Huber-Lang M, Barratt-Due A, Pischke SE, Sandanger Ø, Nilsson PH, Nunn MA, Denk S, Gaus W, Espevik T, Mollnes TE (2014)
    Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice
    J Immunol, 192 (11), 5324-31
    DOI 10.4049/jimmunol.1400341, PubMed 24790148
  8. Lappegård KT, Garred P, Jonasson L, Espevik T, Aukrust P, Yndestad A, Mollnes TE, Hovland A (2014)
    A vital role for complement in heart disease
    Mol Immunol, 61 (2), 126-34
    DOI 10.1016/j.molimm.2014.06.036, PubMed 25037633
  9. Lind A, Brekke K, Pettersen FO, Mollnes TE, Trøseid M, Kvale D (2014)
    A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers
    PLoS One, 9 (1), e85604
    DOI 10.1371/journal.pone.0085604, PubMed 24416431
  10. Neupane SP, Lien L, Martinez P, Aukrust P, Ueland T, Mollnes TE, Hestad K, Bramness JG (2014)
    High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders
    CNS Neurosci Ther, 20 (10), 898-904
    DOI 10.1111/cns.12303, PubMed 24995667
  11. Nymo S, Niyonzima N, Espevik T, Mollnes TE (2014)
    Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF
    Immunobiology, 219 (10), 786-92
    DOI 10.1016/j.imbio.2014.06.006, PubMed 25053140
  12. Ostvik AE, Granlund Av, Gustafsson BI, Torp SH, Espevik T, Mollnes TE, Damås JK, Sandvik AK (2014)
    Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease
    Inflamm Bowel Dis, 20 (6), 995-1003
    DOI 10.1097/MIB.0000000000000035, PubMed 24739633
  13. Owen EP, Würzner R, Leisegang F, Rizkallah P, Whitelaw A, Simpson J, Thomas AD, Harris CL, Giles JL, Hellerud BC, Mollnes TE, Morgan BP, Potter PC, Orren A (2014)
    A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases
    Mol Immunol, 64 (1), 170-6
    DOI 10.1016/j.molimm.2014.11.010, PubMed 25534848
  14. Samstad EO, Niyonzima N, Nymo S, Aune MH, Ryan L, Bakke SS, Lappegård KT, Brekke OL, Lambris JD, Damås JK, Latz E, Mollnes TE, Espevik T (2014)
    Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release
    J Immunol, 192 (6), 2837-45
    DOI 10.4049/jimmunol.1302484, PubMed 24554772
  15. Skjeflo EW, Christiansen D, Espevik T, Nielsen EW, Mollnes TE (2014)
    Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model
    J Immunol, 192 (6), 2857-64
    DOI 10.4049/jimmunol.1300755, PubMed 24516199
  16. Wyller VB, Sørensen Ø, Sulheim D, Fagermoen E, Ueland T, Mollnes TE (2014)
    Plasma cytokine expression in adolescent chronic fatigue syndrome
    Brain Behav Immun, 46, 80-6
    DOI 10.1016/j.bbi.2014.12.025, PubMed 25555530

Publications 2013

  1. Auråen H, Mollnes TE, Bjørtuft Ø, Bakkan PA, Geiran O, Kongerud J, Fiane A, Holm AM (2013)
    Multiorgan procurement increases systemic inflammation in brain dead donors
    Clin Transplant, 27 (4), 613-8
    DOI 10.1111/ctr.12175, PubMed 23803161
  2. Barratt-Due A, Thorgersen EB, Egge K, Pischke S, Sokolov A, Hellerud BC, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn M, Scott H, Mollnes TE (2013)
    Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis
    J Immunol, 191 (2), 819-27
    DOI 10.4049/jimmunol.1201909, PubMed 23761634
  3. Bergseth G, Ludviksen JK, Kirschfink M, Giclas PC, Nilsson B, Mollnes TE (2013)
    An international serum standard for application in assays to detect human complement activation products
    Mol Immunol, 56 (3), 232-9
    DOI 10.1016/j.molimm.2013.05.221, PubMed 23787367
  4. Brekke OL, Waage C, Christiansen D, Fure H, Qu H, Lambris JD, Østerud B, Nielsen EW, Mollnes TE (2013)
    The effects of selective complement and CD14 inhibition on the E. coli-induced tissue factor mRNA upregulation, monocyte tissue factor expression, and tissue factor functional activity in human whole blood
    Adv Exp Med Biol, 735, 123-36
    DOI 10.1007/978-1-4614-4118-2_8, PubMed 23402023
  5. Egge KH, Thorgersen EB, Lindstad JK, Pharo A, Lambris JD, Barratt-Due A, Mollnes TE (2013)
    Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood
    Innate Immun, 20 (1), 68-77
    DOI 10.1177/1753425913482993, PubMed 23669326
  6. Ehrnthaller C, Huber-Lang M, Nilsson P, Bindl R, Redeker S, Recknagel S, Rapp A, Mollnes T, Amling M, Gebhard F, Ignatius A (2013)
    Complement C3 and C5 deficiency affects fracture healing
    PLoS One, 8 (11), e81341
    DOI 10.1371/journal.pone.0081341, PubMed 24260573
  7. Gregersen I, Skjelland M, Holm S, Holven KB, Krogh-Sørensen K, Russell D, Askevold ET, Dahl CP, Ørn S, Gullestad L, Mollnes TE, Ueland T, Aukrust P, Halvorsen B (2013)
    Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis
    PLoS One, 8 (8), e72769
    DOI 10.1371/journal.pone.0072769, PubMed 24023645
  8. Hamre H, Zeller B, Kanellopoulos A, Ruud E, Fosså SD, Loge JH, Aukrust P, Halvorsen B, Mollnes TE, Kiserud CE (2013)
    Serum cytokines and chronic fatigue in adults surviving after childhood leukemia and lymphoma
    Brain Behav Immun, 30, 80-7
    DOI 10.1016/j.bbi.2013.01.006, PubMed 23333795
  9. Happonen KE, Saxne T, Jacobsson L, Sturfelt G, Rönnelid J, Mollnes TE, Heinegård D, Turesson C, Blom AM (2013)
    COMP-C3b complexes in rheumatoid arthritis with severe extraarticular manifestations
    J Rheumatol, 40 (12), 2001-5
    DOI 10.3899/jrheum.130613, PubMed 24187101
  10. Haugaa H, Almaas R, Thorgersen EB, Foss A, Line PD, Sanengen T, Bergmann GB, Ohlin P, Waelgaard L, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2013)
    Clinical experience with microdialysis catheters in pediatric liver transplants
    Liver Transpl, 19 (3), 305-14
    DOI 10.1002/lt.23578, PubMed 23193034
  11. Landsem A, Nielsen EW, Fure H, Christiansen D, Ludviksen JK, Lambris JD, Østerud B, Mollnes TE, Brekke OL (2013)
    C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood
    Clin Exp Immunol, 173 (2), 217-29
    DOI 10.1111/cei.12098, PubMed 23607270
  12. Lappegård KT, Hovland A, Pop GA, Mollnes TE (2013)
    Atrial fibrillation: inflammation in disguise?
    Scand J Immunol, 78 (2), 112-9
    DOI 10.1111/sji.12061, PubMed 23672430
  13. Lau C, Gunnarsen KS, Høydahl LS, Andersen JT, Berntzen G, Pharo A, Lindstad JK, Ludviksen JK, Brekke OL, Barratt-Due A, Nielsen EW, Stokes CR, Espevik T, Sandlie I, Mollnes TE (2013)
    Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation
    J Immunol, 191 (9), 4769-77
    DOI 10.4049/jimmunol.1301653, PubMed 24062486
  14. Mollnes TE, Nilsson PH (2013)
    Letter to editor
    J Clin Biochem Nutr, 52 (3), 253-4
    DOI 10.3164/jcbn.52-3_LtoE, PubMed 23704816
  15. Prohászka Z, Munthe-Fog L, Ueland T, Gombos T, Yndestad A, Förhécz Z, Skjoedt MO, Pozsonyi Z, Gustavsen A, Jánoskuti L, Karádi I, Gullestad L, Dahl CP, Askevold ET, Füst G, Aukrust P, Mollnes TE, Garred P (2013)
    Association of ficolin-3 with severity and outcome of chronic heart failure
    PLoS One, 8 (4), e60976
    DOI 10.1371/journal.pone.0060976, PubMed 23596511
  16. Salvesen B, Curstedt T, Mollnes TE, Saugstad OD (2013)
    Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome
    Neonatology, 105 (2), 128-35
    DOI 10.1159/000356065, PubMed 24356240
  17. Schejbel L, Fadnes D, Permin H, Lappegård KT, Garred P, Mollnes TE (2013)
    Primary complement C5 deficiencies - molecular characterization and clinical review of two families
    Immunobiology, 218 (10), 1304-10
    DOI 10.1016/j.imbio.2013.04.021, PubMed 23743184
  18. Thorgersen EB, Pischke SE, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Hellerud BC, Mollnes TE (2013)
    Systemic CD14 inhibition attenuates organ inflammation in porcine Escherichia coli sepsis
    Infect Immun, 81 (9), 3173-81
    DOI 10.1128/IAI.00390-13, PubMed 23774598
  19. van Vuuren BJ, Bergseth G, Mollnes TE, Shaw AM (2013)
    Electroluminescent TCC, C3dg and fB/Bb epitope assays for profiling complement cascade activation in vitro using an activated complement serum calibration standard
    J Immunol Methods, 402 (1-2), 50-6
    DOI 10.1016/j.jim.2013.11.010, PubMed 24287422
  20. Øvstebø R, Hellum M, Aass HC, Trøseid AM, Brandtzaeg P, Mollnes TE, Henriksson CE (2013)
    Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood
    Innate Immun, 20 (5), 552-60
    DOI 10.1177/1753425913502099, PubMed 24051102

Publications 2012

  1. Almaas R, Hankø E, Mollnes TE, Rootwelt T (2012)
    Dexamethasone reduces bilirubin-induced toxicity and IL-8 and MCP-1 release in human NT2-N neurons
    Brain Res, 1458, 12-7
    DOI 10.1016/j.brainres.2012.04.007, PubMed 22546346
  2. Barratt-Due A, Pischke SE, Brekke OL, Thorgersen EB, Nielsen EW, Espevik T, Huber-Lang M, Mollnes TE (2012)
    Bride and groom in systemic inflammation--the bells ring for complement and Toll in cooperation
    Immunobiology, 217 (11), 1047-56
    DOI 10.1016/j.imbio.2012.07.019, PubMed 22964230
  3. Barratt-Due A, Sokolov A, Gustavsen A, Hellerud BC, Egge K, Pischke SE, Lindstad JK, Pharo A, Castellheim A, Thorgersen EB, Mollnes TE (2012)
    Polyvalent immunoglobulin significantly attenuated the formation of IL-1β in Escherichia coli-induced sepsis in pigs
    Immunobiology, 218 (5), 683-9
    DOI 10.1016/j.imbio.2012.08.268, PubMed 22947599
  4. Bisschops LL, Hoedemaekers CW, Mollnes TE, van der Hoeven JG (2012)
    Rewarming after hypothermia after cardiac arrest shifts the inflammatory balance
    Crit Care Med, 40 (4), 1136-42
    DOI 10.1097/CCM.0b013e3182377050, PubMed 22020246
  5. Christiansen D, Brekke OL, Stenvik J, Lambris JD, Espevik T, Mollnes TE (2012)
    Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood
    Adv Exp Med Biol, 946, 237-51
    DOI 10.1007/978-1-4614-0106-3_14, PubMed 21948372
  6. Granslo HN, Klingenberg C, Fredheim EA, Acharya G, Mollnes TE, Flægstad T (2012)
    Staphylococcus epidermidis biofilms induce lower complement activation in neonates as compared with adults
    Pediatr Res, 73 (3), 294-300
    DOI 10.1038/pr.2012.193, PubMed 23232670
  7. Harboe M, Garred P, Lindstad JK, Pharo A, Müller F, Stahl GL, Lambris JD, Mollnes TE (2012)
    The role of properdin in zymosan- and Escherichia coli-induced complement activation
    J Immunol, 189 (5), 2606-13
    DOI 10.4049/jimmunol.1200269, PubMed 22851705
  8. Haugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Waelgaard L, Pischke SE, Mollnes TE, Inge Tønnessen T (2012)
    Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts
    Liver Transpl, 18 (12), 1421-9
    DOI 10.1002/lt.23503, PubMed 22767413
  9. Hovland A, Hardersen R, Nielsen EW, Enebakk T, Christiansen D, Ludviksen JK, Mollnes TE, Lappegård KT (2012)
    Complement profile and activation mechanisms by different LDL apheresis systems
    Acta Biomater, 8 (6), 2288-96
    DOI 10.1016/j.actbio.2012.02.017, PubMed 22373816
  10. Hovland A, Lappegård KT, Mollnes TE (2012)
    LDL apheresis and inflammation--implications for atherosclerosis
    Scand J Immunol, 76 (3), 229-36
    DOI 10.1111/j.1365-3083.2012.02734.x, PubMed 22670805
  11. Håugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2012)
    Early bedside detection of ischemia and rejection in liver transplants by microdialysis
    Liver Transpl, 18 (7), 839-49
    DOI 10.1002/lt.23425, PubMed 22407878
  12. Kvarnström A, Sokolov A, Swartling T, Kurlberg G, Mollnes TE, Bengtsson A (2012)
    Alternative pathway activation of complement in laparoscopic and open rectal surgery
    Scand J Immunol, 76 (1), 49-53
    DOI 10.1111/j.1365-3083.2012.02702.x, PubMed 22486843
  13. Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lambris JD, Lacík I, Mollnes TE, Espevik T (2012)
    The induction of cytokines by polycation containing microspheres by a complement dependent mechanism
    Biomaterials, 34 (3), 621-30
    DOI 10.1016/j.biomaterials.2012.10.012, PubMed 23103159
  14. Rødland EK, Ueland T, Bjørnsen S, Sagen EL, Dahl CP, Naalsund A, Mollnes TE, Brosstad FR, Müller F, Aukrust P, Frøland SS (2012)
    Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis
    BMC Infect Dis, 12, 144
    DOI 10.1186/1471-2334-12-144, PubMed 22731696
  15. Sokolov A, Hellerud BC, Johannessen EA, Mollnes TE (2012)
    Inflammatory response induced by candidate biomaterials of an implantable microfabricated sensor
    J Biomed Mater Res A, 100 (5), 1142-50
    DOI 10.1002/jbm.a.34054, PubMed 22337626
  16. Sokolov A, Hellerud BC, Tønnessen TI, Johannessen EA, Mollnes TE (2012)
    Activation of coagulation and platelets by candidate membranes of implantable devices in a whole blood model without soluble anticoagulant
    J Biomed Mater Res A, 101 (2), 575-81
    DOI 10.1002/jbm.a.34348, PubMed 22949225
  17. Ørn S, Ueland T, Manhenke C, Sandanger Ø, Godang K, Yndestad A, Mollnes TE, Dickstein K, Aukrust P (2012)
    Increased interleukin-1β levels are associated with left ventricular hypertrophy and remodelling following acute ST segment elevation myocardial infarction treated by primary percutaneous coronary intervention
    J Intern Med, 272 (3), 267-76
    DOI 10.1111/j.1365-2796.2012.02517.x, PubMed 22243053

Publications 2011

  1. Barratt-Due A, Johansen HT, Sokolov A, Thorgersen EB, Hellerud BC, Reubsaet JL, Seip KF, Tønnessen TI, Lindstad JK, Pharo A, Castellheim A, Mollnes TE, Nielsen EW (2011)
    The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis
    Shock, 36 (5), 517-23
    DOI 10.1097/SHK.0b013e3182336a34, PubMed 21921836
  2. Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD, Nunn MA, Mollnes TE (2011)
    Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans
    J Immunol, 187 (9), 4913-9
    DOI 10.4049/jimmunol.1101000, PubMed 21964028
  3. Berdal JE, Mollnes TE, Wæhre T, Olstad OK, Halvorsen B, Ueland T, Laake JH, Furuseth MT, Maagaard A, Kjekshus H, Aukrust P, Jonassen CM (2011)
    Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza
    J Infect, 63 (4), 308-16
    DOI 10.1016/j.jinf.2011.07.004, PubMed 21781987
  4. Bergseth G, Lambris JD, Mollnes TE, Lappegård KT (2011)
    Artificial surface-induced inflammation relies on complement factor 5: proof from a deficient person
    Ann Thorac Surg, 91 (2), 527-33
    DOI 10.1016/j.athoracsur.2010.10.084, PubMed 21256307
  5. Brekke OL, Hellerud BC, Christiansen D, Fure H, Castellheim A, Nielsen EW, Pharo A, Lindstad JK, Bergseth G, Leslie G, Lambris JD, Brandtzaeg P, Mollnes TE (2011)
    Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood
    Mol Immunol, 48 (15-16), 2159-69
    DOI 10.1016/j.molimm.2011.07.011, PubMed 21839519
  6. Chavez SA, Martinko AJ, Lau C, Pham MN, Cheng K, Bevan DE, Mollnes TE, Yin H (2011)
    Development of β-amino alcohol derivatives that inhibit Toll-like receptor 4 mediated inflammatory response as potential antiseptics
    J Med Chem, 54 (13), 4659-69
    DOI 10.1021/jm2003365, PubMed 21591694
  7. Fredheim EG, Granslo HN, Flægstad T, Figenschau Y, Rohde H, Sadovskaya I, Mollnes TE, Klingenberg C (2011)
    Staphylococcus epidermidis polysaccharide intercellular adhesin activates complement
    FEMS Immunol Med Microbiol, 63 (2), 269-80
    DOI 10.1111/j.1574-695X.2011.00854.x, PubMed 22077230
  8. Grimnes G, Beckman H, Lappegård KT, Mollnes TE, Skogen V (2011)
    Recurrent meningococcal sepsis in a presumptive immunocompetent host shown to be complement C5 deficient-a case report
    APMIS, 119 (7), 479-84
    DOI 10.1111/j.1600-0463.2011.02740.x, PubMed 21635555
  9. Harboe M, Thorgersen EB, Mollnes TE (2011)
    Advances in assay of complement function and activation
    Adv Drug Deliv Rev, 63 (12), 976-87
    DOI 10.1016/j.addr.2011.05.010, PubMed 21664392
  10. Hovland A, Marcovina S, Hardersen R, Enebakk T, Mollnes TE, Lappegård KT (2011)
    Three different LDL apheresis columns efficiently and equally reduce lipoprotein(a) concentrations in patients with familial hypercholesterolemia and small apolipoprotein(a) particles
    Transfus Apher Sci, 46 (1), 73-6
    DOI 10.1016/j.transci.2011.11.016, PubMed 22206792
  11. Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lacík I, Espevik T, Mollnes TE (2011)
    Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model
    Acta Biomater, 7 (6), 2566-78
    DOI 10.1016/j.actbio.2011.03.011, PubMed 21402181
  12. Sokolov A, Hellerud BC, Lambris JD, Johannessen EA, Mollnes TE (2011)
    Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor
    J Diabetes Sci Technol, 5 (6), 1490-8
    DOI 10.1177/193229681100500625, PubMed 22226271
  13. Sokolov A, Hellerud BC, Pharo A, Johannessen EA, Mollnes TE (2011)
    Complement activation by candidate biomaterials of an implantable microfabricated medical device
    J Biomed Mater Res B Appl Biomater, 98 (2), 323-9
    DOI 10.1002/jbm.b.31855, PubMed 21648060
  14. Søyland E, Heier I, Rodríguez-Gallego C, Mollnes TE, Johansen FE, Holven KB, Halvorsen B, Aukrust P, Jahnsen FL, de la Rosa Carrillo D, Krogstad AL, Nenseter MS (2011)
    Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis
    Br J Dermatol, 164 (2), 344-55
    DOI 10.1111/j.1365-2133.2010.10149.x, PubMed 21271993
  15. Torfoss D, Sandstad B, Mollnes TE, Høiby EA, Holte H, Bjerner J, Bjøro T, Gaudernack G, Kvalheim G, Kvaløy S (2011)
    The mild inflammatory response in febrile neutropenic lymphoma patients with low risk of complications is more pronounced in patients receiving tobramycin once daily compared with three times daily
    Scand J Immunol, 74 (6), 632-9
    DOI 10.1111/j.1365-3083.2011.02618.x, PubMed 21883353
  16. van Kuilenburg J, Lappegård KT, Sexton J, Plesiewicz I, Lap P, Bouwels L, Sprong T, Mollnes TE, Verheugt F, van Heerde WL, Pop GA (2011)
    Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment
    J Clin Lipidol, 5 (4), 273-80
    DOI 10.1016/j.jacl.2011.05.003, PubMed 21784372

Publications 2010

  1. Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Brekke OL, Christiansen D, Lambris JD, Mollnes TE (2010)
    Selective inhibition of TNF-alpha or IL-1 beta does not affect E. coli-induced inflammation in human whole blood
    Mol Immunol, 47 (9), 1774-82
    DOI 10.1016/j.molimm.2010.02.026, PubMed 20334922
  2. Dalen ML, Alme TN, Munkeby BH, Løberg EM, Pripp AH, Mollnes TE, Rootwelt T, Saugstad OD (2010)
    Early protective effect of hypothermia in newborn pigs after hyperoxic, but not after normoxic, reoxygenation
    J Perinat Med, 38 (5), 545-56
    DOI 10.1515/JPM.2010.081, PubMed 20629493
  3. Eagan TM, Aukrust P, Bakke PS, Damås JK, Skorge TD, Hardie JA, Ueland T, Mollnes TE (2010)
    Systemic mannose-binding lectin is not associated with Chronic Obstructive Pulmonary Disease
    Respir Med, 104 (2), 283-90
    DOI 10.1016/j.rmed.2009.09.015, PubMed 19836222
  4. Eagan TM, Aukrust P, Ueland T, Hardie JA, Johannessen A, Mollnes TE, Damås JK, Bakke PS, Wagner PD (2010)
    Body composition and plasma levels of inflammatory biomarkers in COPD
    Eur Respir J, 36 (5), 1027-33
    DOI 10.1183/09031936.00194209, PubMed 20413541
  5. Eagan TM, Damås JK, Ueland T, Voll-Aanerud M, Mollnes TE, Hardie JA, Bakke PS, Aukrust P (2010)
    Neutrophil gelatinase-associated lipocalin: a biomarker in COPD
    Chest, 138 (4), 888-95
    DOI 10.1378/chest.09-2718, PubMed 20495108
  6. Granslo HN, Klingenberg C, Fredheim EG, Rønnestad A, Mollnes TE, Flaegstad T (2010)
    Arginine catabolic mobile element is associated with low antibiotic resistance and low pathogenicity in Staphylococcus epidermidis from neonates
    Pediatr Res, 68 (3), 237-41
    DOI 10.1203/PDR.0b013e3181eb01e0, PubMed 20703143
  7. Hellerud BC, Nielsen EW, Thorgersen EB, Lindstad JK, Pharo A, Tønnessen TI, Castellheim A, Mollnes TE, Brandtzaeg P (2010)
    Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis
    Crit Care Med, 38 (6), 1467-74
    DOI 10.1097/CCM.0b013e3181de8c94, PubMed 20400898
  8. Hoedemaekers C, van Deuren M, Sprong T, Pickkers P, Mollnes TE, Klasen I, van der Hoeven J (2010)
    The complement system is activated in a biphasic pattern after coronary artery bypass grafting
    Ann Thorac Surg, 89 (3), 710-6
    DOI 10.1016/j.athoracsur.2009.11.049, PubMed 20172115
  9. Hovland A, Hardersen R, Enebakk T, Mollnes TE, Lappegård KT (2010)
    Patient tolerance regarding different low-density lipoprotein apheresis columns: frequent minor side effects and high patient satisfaction
    J Clin Lipidol, 5 (1), 45-9
    DOI 10.1016/j.jacl.2010.11.003, PubMed 21262506
  10. Hovland A, Hardersen R, Mollnes TE, Lappegård KT (2010)
    Selective whole blood lipoprotein apheresis to prevent pancreatitis in drug refractory hypertriglyceridemia
    JOP, 11 (5), 467-9
    PubMed 20818118
  11. Hovland A, Hardersen R, Nielsen EW, Mollnes TE, Lappegård KT (2010)
    Hematologic and hemostatic changes induced by different columns during LDL apheresis
    J Clin Apher, 25 (5), 294-300
    DOI 10.1002/jca.20256, PubMed 20806414
  12. Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
    The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
    Immunity, 33 (4), 583-96
    DOI 10.1016/j.immuni.2010.09.010, PubMed 20933442
  13. Johannessen E, Krushinitskaya O, Sokolov A, Philipp H, Hoogerwerf A, Hinderling C, Kautio K, Lenkkeri J, Strömmer E, Kondratyev V, Tønnessen TI, Mollnes TE, Jakobsen H, Zimmer E, Akselsen B (2010)
    Toward an injectable continuous osmotic glucose sensor
    J Diabetes Sci Technol, 4 (4), 882-92
    DOI 10.1177/193229681000400417, PubMed 20663452
  14. Kourtzelis I, Markiewski MM, Doumas M, Rafail S, Kambas K, Mitroulis I, Panagoutsos S, Passadakis P, Vargemezis V, Magotti P, Qu H, Mollnes TE, Ritis K, Lambris JD (2010)
    Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis
    Blood, 116 (4), 631-9
    DOI 10.1182/blood-2010-01-264051, PubMed 20424189
  15. Salvesen B, Stenvik J, Rossetti C, Saugstad OD, Espevik T, Mollnes TE (2010)
    Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner
    Mol Immunol, 47 (6), 1226-34
    DOI 10.1016/j.molimm.2009.12.015, PubMed 20092898
  16. Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, Magotti P, Ivanciu L, Lupu C, Mollnes TE, Taylor FB, Kinasewitz G, Lambris JD, Lupu F (2010)
    Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis
    Blood, 116 (6), 1002-10
    DOI 10.1182/blood-2010-02-269746, PubMed 20466856
  17. Thiara AS, Andersen VY, Videm V, Mollnes TE, Svennevig K, Hoel TN, Fiane AE (2010)
    Comparable biocompatibility of Phisio- and Bioline-coated cardiopulmonary bypass circuits indicated by the inflammatory response
    Perfusion, 25 (1), 9-16
    DOI 10.1177/0267659110362822, PubMed 20172900
  18. Thiara AS, Mollnes TE, Videm V, Andersen VY, Svennevig K, Kolset SO, Fiane AE (2010)
    Biocompatibility and pathways of initial complement pathway activation with Phisio- and PMEA-coated cardiopulmonary bypass circuits during open-heart surgery
    Perfusion, 26 (2), 107-14
    DOI 10.1177/0267659110392438, PubMed 21177724
  19. Wester T, Häggblad E, Awan ZA, Barratt-Due A, Kvernebo M, Halvorsen PS, Mollnes TE, Kvernebo K (2010)
    Assessments of skin and tongue microcirculation reveals major changes in porcine sepsis
    Clin Physiol Funct Imaging, 31 (2), 151-8
    DOI 10.1111/j.1475-097X.2010.00994.x, PubMed 21087397

Publications 2009

  1. Bexborn F, Engberg AE, Sandholm K, Mollnes TE, Hong J, Nilsson Ekdahl K (2009)
    Hirudin versus heparin for use in whole blood in vitro biocompatibility models
    J Biomed Mater Res A, 89 (4), 951-9
    DOI 10.1002/jbm.a.32034, PubMed 18470919
  2. Castellheim A, Brekke OL, Espevik T, Harboe M, Mollnes TE (2009)
    Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis
    Scand J Immunol, 69 (6), 479-91
    DOI 10.1111/j.1365-3083.2009.02255.x, PubMed 19439008
  3. Corallini F, Bossi F, Gonelli A, Tripodo C, Castellino G, Mollnes TE, Tedesco F, Rizzi L, Trotta F, Zauli G, Secchiero P (2009)
    The soluble terminal complement complex (SC5b-9) up-regulates osteoprotegerin expression and release by endothelial cells: implications in rheumatoid arthritis
    Rheumatology (Oxford), 48 (3), 293-8
    DOI 10.1093/rheumatology/ken495, PubMed 19168833
  4. Eagan TM, Ueland T, Wagner PD, Hardie JA, Mollnes TE, Damås JK, Aukrust P, Bakke PS (2009)
    Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study
    Eur Respir J, 35 (3), 540-8
    DOI 10.1183/09031936.00088209, PubMed 19643942
  5. Eggum R, Ueland T, Mollnes TE, Videm V, Fiane AE, Aukrust P, Lindberg HL (2009)
    Perfusion temperature, thyroid hormones and inflammation during pediatric cardiac surgery
    Interact Cardiovasc Thorac Surg, 10 (1), 76-80
    DOI 10.1510/icvts.2009.213876, PubMed 19822605
  6. Harboe M, Garred P, Karlstrøm E, Lindstad JK, Stahl GL, Mollnes TE (2009)
    The down-stream effects of mannan-induced lectin complement pathway activation depend quantitatively on alternative pathway amplification
    Mol Immunol, 47 (2-3), 373-80
    DOI 10.1016/j.molimm.2009.09.005, PubMed 19800125
  7. Hellerud BC, Aase A, Herstad TK, Naess LM, Kristiansen LH, Trøseid AM, Harboe M, Lappegård KT, Brandtzaeg P, Høiby EA, Mollnes TE (2009)
    Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies
    Infect Immun, 78 (2), 802-9
    DOI 10.1128/IAI.01044-09, PubMed 19933829
  8. Hoel TN, Thiara AS, Videm V, Fiane AE, Mollnes TE, Castellheim A, Svennevig JL (2009)
    In vitro evaluation of PHISIO-coated sets for pediatric cardiac surgery
    Scand Cardiovasc J, 43 (2), 129-35
    DOI 10.1080/14017430802302316, PubMed 19294579
  9. Hovland A, Hardersen R, Sexton J, Mollnes TE, Lappegård KT (2009)
    Different inflammatory responses induced by three LDL-lowering apheresis columns
    J Clin Apher, 24 (6), 247-53
    DOI 10.1002/jca.20223, PubMed 19927364
  10. Kåsin JI, Kjekshus J, Aukrust P, Mollnes TE, Wagstaff A (2009)
    A helicopter flight does not induce significant changes in systemic biomarker profiles
    Scand J Clin Lab Invest, 69 (4), 462-74
    DOI 10.1080/00365510902745360, PubMed 19333819
  11. Lappegård KT, Christiansen D, Pharo A, Thorgersen EB, Hellerud BC, Lindstad J, Nielsen EW, Bergseth G, Fadnes D, Abrahamsen TG, Høiby EA, Schejbel L, Garred P, Lambris JD, Harboe M, Mollnes TE (2009)
    Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature
    Proc Natl Acad Sci U S A, 106 (37), 15861-6
    DOI 10.1073/pnas.0903613106, PubMed 19717455
  12. Manderson GA, Martin M, Onnerfjord P, Saxne T, Schmidtchen A, Mollnes TE, Heinegård D, Blom AM (2009)
    Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system
    Mol Immunol, 46 (16), 3388-98
    DOI 10.1016/j.molimm.2009.07.011, PubMed 19674792
  13. Martin M, Gottsäter A, Nilsson PM, Mollnes TE, Lindblad B, Blom AM (2009)
    Complement activation and plasma levels of C4b-binding protein in critical limb ischemia patients
    J Vasc Surg, 50 (1), 100-6
    DOI 10.1016/j.jvs.2008.12.033, PubMed 19563958
  14. Natvig JB, Mollnes TE (2009)
    Professor emeritus Morten Harboe, one of the founders of Scandinavian Journal of Immunology, turns 80
    Scand. J. Immunol., 69 (6), 469-470
    DOI 10.1111/j.1365-3083.2009.02259.x
  15. Nielsen EW, Hellerud BC, Thorgersen EB, Castellheim A, Pharo A, Lindstad J, Tønnessen TI, Brandtzaeg P, Mollnes TE (2009)
    A new dynamic porcine model of meningococcal shock
    Shock, 32 (3), 302-9
    DOI 10.1097/SHK.0b013e31819c37be, PubMed 19174740
  16. Orn S, Breland UM, Mollnes TE, Manhenke C, Dickstein K, Aukrust P, Ueland T (2009)
    The chemokine network in relation to infarct size and left ventricular remodeling following acute myocardial infarction
    Am J Cardiol, 104 (9), 1179-83
    DOI 10.1016/j.amjcard.2009.06.028, PubMed 19840558
  17. Pedersen ED, Løberg EM, Vege E, Daha MR, Maehlen J, Mollnes TE (2009)
    In situ deposition of complement in human acute brain ischaemia
    Scand J Immunol, 69 (6), 555-62
    DOI 10.1111/j.1365-3083.2009.02253.x, PubMed 19439017
  18. Salvesen B, Mollnes TE (2009)
    Pathway-specific complement activity in pigs evaluated with a human functional complement assay
    Mol Immunol, 46 (8-9), 1620-5
    DOI 10.1016/j.molimm.2009.02.028, PubMed 19328551
  19. Siezenga MA, Chandie Shaw PK, van der Geest RN, Mollnes TE, Daha MR, Rabelink TJ, Berger SP (2009)
    Enhanced complement activation is part of the unfavourable cardiovascular risk profile in South Asians
    Clin Exp Immunol, 157 (1), 98-103
    DOI 10.1111/j.1365-2249.2009.03959.x, PubMed 19659775
  20. Sikkeland LI, Eduard W, Stangeland AM, Thorgersen EB, Haug T, Aukrust P, Halvorsen B, Mollnes TE, Kongerud J (2009)
    Occupational exposure to bacterial single cell protein induces inflammation in lung and blood
    Inhal Toxicol, 21 (8), 674-81
    DOI 10.1080/08958370802491425, PubMed 19558225
  21. Sprong T, Mollnes TE, Neeleman C, Swinkels D, Netea MG, van der Meer JW, van Deuren M (2009)
    Mannose-binding lectin is a critical factor in systemic complement activation during meningococcal septic shock
    Clin Infect Dis, 49 (9), 1380-6
    DOI 10.1086/606054, PubMed 19793001
  22. Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE (2009)
    CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs
    FASEB J, 24 (3), 712-22
    DOI 10.1096/fj.09-140798, PubMed 19841036
  23. Thorgersen EB, Ludviksen JK, Lambris JD, Sfyroera G, Nielsen EW, Mollnes TE (2009)
    Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity
    Innate Immun, 16 (4), 254-64
    DOI 10.1177/1753425909340420, PubMed 19710096
  24. Trøseid M, Lappegård KT, Mollnes TE, Arnesen H, Seljeflot I (2009)
    The effect of exercise on serum levels of interleukin-18 and components of the metabolic syndrome
    Metab Syndr Relat Disord, 7 (6), 579-84
    DOI 10.1089/met.2009.0003, PubMed 19900154
  25. Ørn S, Manhenke C, Ueland T, Damås JK, Mollnes TE, Edvardsen T, Aukrust P, Dickstein K (2009)
    C-reactive protein, infarct size, microvascular obstruction, and left-ventricular remodelling following acute myocardial infarction
    Eur Heart J, 30 (10), 1180-6
    DOI 10.1093/eurheartj/ehp070, PubMed 19299430

Publications 2008

  1. Asberg AE, Mollnes TE, Videm V (2008)
    Complement activation by neutrophil granulocytes
    Scand J Immunol, 67 (4), 354-61
    DOI 10.1111/j.1365-3083.2008.02077.x, PubMed 18248527
  2. Brekke OL, Christiansen D, Fure H, Pharo A, Fung M, Riesenfeld J, Mollnes TE (2008)
    Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood
    Mol Immunol, 45 (14), 3804-13
    DOI 10.1016/j.molimm.2008.05.017, PubMed 18606453
  3. Castellheim A, Hoel TN, Videm V, Fosse E, Pharo A, Svennevig JL, Fiane AE, Mollnes TE (2008)
    Biomarker profile in off-pump and on-pump coronary artery bypass grafting surgery in low-risk patients
    Ann Thorac Surg, 85 (6), 1994-2002
    DOI 10.1016/j.athoracsur.2008.03.012, PubMed 18498809
  4. Castellheim A, Thorgersen EB, Hellerud BC, Pharo A, Johansen HT, Brosstad F, Gaustad P, Brun H, Fosse E, Tønnessen TI, Nielsen EW, Mollnes TE (2008)
    New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs
    Scand J Immunol, 68 (1), 75-84
    DOI 10.1111/j.1365-3083.2008.02122.x, PubMed 18466195
  5. Dalen ML, Frøyland E, Saugstad OD, Mollnes TE, Rootwelt T (2008)
    Post-hypoxic hypothermia is protective in human NT2-N neurons regardless of oxygen concentration during reoxygenation
    Brain Res, 1259, 80-9
    DOI 10.1016/j.brainres.2008.12.055, PubMed 19146835
  6. Eggum R, Ueland T, Mollnes TE, Videm V, Aukrust P, Fiane AE, Lindberg HL (2008)
    Effect of perfusion temperature on the inflammatory response during pediatric cardiac surgery
    Ann Thorac Surg, 85 (2), 611-7
    DOI 10.1016/j.athoracsur.2007.10.062, PubMed 18222275
  7. Harboe M, Mollnes TE (2008)
    The alternative complement pathway revisited
    J Cell Mol Med, 12 (4), 1074-84
    DOI 10.1111/j.1582-4934.2008.00350.x, PubMed 18419792
  8. Hellerud BC, Stenvik J, Espevik T, Lambris JD, Mollnes TE, Brandtzaeg P (2008)
    Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation
    Infect Immun, 76 (9), 4183-9
    DOI 10.1128/IAI.00195-08, PubMed 18591229
  9. Lappegård KT, Bergseth G, Riesenfeld J, Pharo A, Magotti P, Lambris JD, Mollnes TE (2008)
    The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent
    J Biomed Mater Res A, 87 (1), 129-35
    DOI 10.1002/jbm.a.31750, PubMed 18085644
  10. Mollnes TE (2008)
    High mobility group box-1 protein--one step closer to the clinic?
    Crit Care, 12 (4), 168
    DOI 10.1186/cc6944, PubMed 18671827
  11. Mollnes TE, Castellheim A, Lindenskov PH, Salvesen B, Saugstad OD (2008)
    The role of complement in meconium aspiration syndrome
    J Perinatol, 28 Suppl 3, S116-9
    DOI 10.1038/jp.2008.148, PubMed 19057601
  12. Mollnes TE, Christiansen D, Brekke OL, Espevik T (2008)
    Hypothesis: combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response
    Adv Exp Med Biol, 632, 253-63
    DOI 10.1007/978-0-387-78952-1_18, PubMed 19025127
  13. Saethre M, Schneider MK, Lambris JD, Magotti P, Haraldsen G, Seebach JD, Mollnes TE (2008)
    Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model
    J Immunol, 180 (9), 6346-53
    DOI 10.4049/jimmunol.180.9.6346, PubMed 18424758
  14. Sagedal S, Thiel S, Hansen TK, Mollnes TE, Rollag H, Hartmann A (2008)
    Impact of the complement lectin pathway on cytomegalovirus disease early after kidney transplantation
    Nephrol Dial Transplant, 23 (12), 4054-60
    DOI 10.1093/ndt/gfn355, PubMed 18577532
  15. Salvesen B, Fung M, Saugstad OD, Mollnes TE (2008)
    Role of complement and CD14 in meconium-induced cytokine formation
    Pediatrics, 121 (3), e496-505
    DOI 10.1542/peds.2007-0878, PubMed 18299306
  16. Salvesen B, Mollnes TE, Saugstad OD (2008)
    Albumin lavage does not improve the outcome of meconium aspiration syndrome
    J Matern Fetal Neonatal Med, 21 (10), 719-25
    DOI 10.1080/14767050802255561, PubMed 19012188
  17. Salvesen B, Nielsen EW, Harboe M, Saugstad OD, Mollnes TE (2008)
    Mechanisms of complement activation and effects of C1-inhibitor on the meconium-induced inflammatory reaction in human cord blood
    Mol Immunol, 46 (4), 688-94
    DOI 10.1016/j.molimm.2008.09.001, PubMed 18950866
  18. Thorgersen EB, Macagno A, Rossetti C, Mollnes TE (2008)
    Cyanobacterial LPS antagonist (CyP)-a novel and efficient inhibitor of Escherichia coli LPS-induced cytokine response in the pig
    Mol Immunol, 45 (13), 3553-7
    DOI 10.1016/j.molimm.2008.05.005, PubMed 18571239
  19. Thorgersen EB, Pharo A, Haverson K, Axelsen AK, Gaustad P, Kotwal GJ, Sfyroera G, Mollnes TE (2008)
    Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood
    Infect Immun, 77 (2), 725-32
    DOI 10.1128/IAI.01305-08, PubMed 19047409
  20. Waelgaard L, Thorgersen EB, Line PD, Foss A, Mollnes TE, Tønnessen TI (2008)
    Microdialysis monitoring of liver grafts by metabolic parameters, cytokine production, and complement activation
    Transplantation, 86 (8), 1096-103
    DOI 10.1097/TP.0b013e31818775ca, PubMed 18946348

Publications 2007

  1. Brekke OL, Christiansen D, Fure H, Fung M, Mollnes TE (2007)
    The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human whole blood
    J Leukoc Biol, 81 (6), 1404-13
    DOI 10.1189/jlb.0806538, PubMed 17389579
  2. Hoel TN, Videm V, Mollnes TE, Saatvedt K, Brosstad F, Fiane AE, Fosse E, Svennevig JL (2007)
    Off-pump cardiac surgery abolishes complement activation
    Perfusion, 22 (4), 251-6
    DOI 10.1177/0267659107084142, PubMed 18181513
  3. Markiewski MM, Nilsson B, Ekdahl KN, Mollnes TE, Lambris JD (2007)
    Complement and coagulation: strangers or partners in crime?
    Trends Immunol, 28 (4), 184-92
    DOI 10.1016/j.it.2007.02.006, PubMed 17336159
  4. Mollnes TE, Jokiranta TS, Truedsson L, Nilsson B, Rodriguez de Cordoba S, Kirschfink M (2007)
    Complement analysis in the 21st century
    Mol Immunol, 44 (16), 3838-49
    DOI 10.1016/j.molimm.2007.06.150, PubMed 17768101
  5. Pedersen ED, Aass HC, Rootwelt T, Fung M, Lambris JD, Mollnes TE (2007)
    CD59 efficiently protects human NT2-N neurons against complement-mediated damage
    Scand J Immunol, 66 (2-3), 345-51
    DOI 10.1111/j.1365-3083.2007.01959.x, PubMed 17635812
  6. Roestenberg M, McCall M, Mollnes TE, van Deuren M, Sprong T, Klasen I, Hermsen CC, Sauerwein RW, van der Ven A (2007)
    Complement activation in experimental human malaria infection
    Trans R Soc Trop Med Hyg, 101 (7), 643-9
    DOI 10.1016/j.trstmh.2007.02.023, PubMed 17481680
  7. Saethre M, Baumann BC, Fung M, Seebach JD, Mollnes TE (2007)
    Characterization of natural human anti-non-gal antibodies and their effect on activation of porcine gal-deficient endothelial cells
    Transplantation, 84 (2), 244-50
    DOI 10.1097/01.tp.0000268815.90675.d5, PubMed 17667817
  8. Sikkeland LI, Thorgersen EB, Haug T, Mollnes TE (2007)
    Complement activation and cytokine response by BioProtein, a bacterial single cell protein
    Clin Exp Immunol, 148 (1), 146-52
    DOI 10.1111/j.1365-2249.2007.03339.x, PubMed 17302729
  9. Ødegård A, Aasland J, Myhre HO, Mollnes TE, Videm V (2007)
    The inflammatory response to stent grafting of the thoracic aorta
    Int Angiol, 26 (3), 219-27
    PubMed 17622202

Publications 2006

  1. Drogset JO, Grøntvedt T, Jessen V, Tegnander A, Mollnes TE, Bergh K (2006)
    Comparison of in vitro and in vivo complement activation by metal and bioabsorbable screws used in anterior cruciate ligament reconstruction
    Arthroscopy, 22 (5), 489-96
    DOI 10.1016/j.arthro.2006.03.011, PubMed 16651157
  2. Frøyland E, Pedersen ED, Kvissel AK, Almaas R, Pharo A, Skålhegg BS, Mollnes TE, Rootwelt T (2006)
    Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons
    Brain Res, 1113 (1), 64-73
    DOI 10.1016/j.brainres.2006.07.051, PubMed 16919250
  3. Harboe M, Garred P, Borgen MS, Stahl GL, Roos A, Mollnes TE (2006)
    Design of a complement mannose-binding lectin pathway-specific activation system applicable at low serum dilutions
    Clin Exp Immunol, 144 (3), 512-20
    DOI 10.1111/j.1365-2249.2006.03072.x, PubMed 16734621
  4. Mollnes TE, Kirschfink M (2006)
    Strategies of therapeutic complement inhibition
    Mol Immunol, 43 (1-2), 107-21
    DOI 10.1016/j.molimm.2005.06.014, PubMed 16011851
  5. Mollnes TE, Kirschfink M (2006)
    Complement analysis in clinic and research
    Adv Exp Med Biol, 586, 361-80
    DOI 10.1007/0-387-34134-X_24, PubMed 16893084
  6. Nielsen EW, Waage C, Fure H, Brekke OL, Sfyroera G, Lambris JD, Mollnes TE (2006)
    Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement
    Mol Immunol, 44 (8), 1819-26
    DOI 10.1016/j.molimm.2006.10.003, PubMed 17101176
  7. Nilsson B, Ekdahl KN, Mollnes TE, Lambris JD (2006)
    The role of complement in biomaterial-induced inflammation
    Mol Immunol, 44 (1-3), 82-94
    DOI 10.1016/j.molimm.2006.06.020, PubMed 16905192
  8. Pedersen ED, Frøyland E, Kvissel AK, Pharo AM, Skålhegg BS, Rootwelt T, Mollnes TE (2006)
    Expression of complement regulators and receptors on human NT2-N neurons--effect of hypoxia and reoxygenation
    Mol Immunol, 44 (9), 2459-68
    DOI 10.1016/j.molimm.2006.10.022, PubMed 17116331
  9. Saethre M, Lea T, Borgen MS, Fiane AE, Michaelsen TE, Thorsby E, Haraldsen G, Mollnes TE (2006)
    Human complement-activating immunoglobulin (Ig)G3 antibodies are essential for porcine endothelial cell activation
    Xenotransplantation, 13 (3), 215-23
    DOI 10.1111/j.1399-3089.2006.00289.x, PubMed 16756564
  10. Sprong T, Roos D, Weemaes C, Neeleman C, Geesing CL, Mollnes TE, van Deuren M (2006)
    Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections
    Blood, 107 (12), 4865-70
    DOI 10.1182/blood-2005-07-2820, PubMed 16527897
  11. Thorgersen EB, Ghebremariam YT, Thurman JM, Fung M, Nielsen EW, Holers VM, Kotwal GJ, Mollnes TE (2006)
    Candidate inhibitors of porcine complement
    Mol Immunol, 44 (8), 1827-34
    DOI 10.1016/j.molimm.2006.10.004, PubMed 17109963
  12. Ueland T, Espevik T, Kjekshus J, Gullestad L, Omland T, Squire IB, Frøland SS, Mollnes TE, Dickstein K, Aukrust P (2006)
    Mannose binding lectin and soluble Toll-like receptor 2 in heart failure following acute myocardial infarction
    J Card Fail, 12 (8), 659-63
    DOI 10.1016/j.cardfail.2006.07.002, PubMed 17045187
  13. Waelgaard L, Pharo A, Tønnessen TI, Mollnes TE (2006)
    Microdialysis for monitoring inflammation: efficient recovery of cytokines and anaphylotoxins provided optimal catheter pore size and fluid velocity conditions
    Scand J Immunol, 64 (3), 345-52
    DOI 10.1111/j.1365-3083.2006.01826.x, PubMed 16918704

Publications 2005

  1. Castellheim A, Lindenskov PH, Pharo A, Aamodt G, Saugstad OD, Mollnes TE (2005)
    Meconium aspiration syndrome induces complement-associated systemic inflammatory response in newborn piglets
    Scand J Immunol, 61 (3), 217-25
    DOI 10.1111/j.1365-3083.2005.01532.x, PubMed 15787738
  2. Fevang B, Mollnes TE, Holm AM, Ueland T, Heggelund L, Damås JK, Aukrust P, Frøland SS (2005)
    Common variable immunodeficiency and the complement system; low mannose-binding lectin levels are associated with bronchiectasis
    Clin Exp Immunol, 142 (3), 576-84
    DOI 10.1111/j.1365-2249.2005.02951.x, PubMed 16297171
  3. Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland S, Aukrust P, Mollnes TE (2005)
    Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischaemia, and rejection after human heart transplantation
    Eur Heart J, 26 (16), 1660-5
    DOI 10.1093/eurheartj/ehi198, PubMed 15821010
  4. Heggelund L, Mollnes TE, Espevik T, Müller F, Kristiansen KI, Aukrust P, Frøland SS (2005)
    Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection
    Eur J Clin Invest, 35 (12), 765-70
    DOI 10.1111/j.1365-2362.2005.01579.x, PubMed 16313253
  5. Hognestad A, Endresen K, Wergeland R, Mellembakken JR, Mollnes TE, Omland T, Kjekshus JK, Aukrust P, Andreassen AK (2005)
    Inflammatory response and re-stenosis after percutaneous coronary intervention in heart transplant recipients and patients with native atherosclerosis
    J Heart Lung Transplant, 24 (8), 1026-32
    DOI 10.1016/j.healun.2004.07.018, PubMed 16102437
  6. Lappegård KT, Bergseth G, Riesenfeld J, Sexton J, Mollnes TE (2005)
    Role of granulocytes and monocytes in the polyvinyl chloride-induced synthesis of interleukin 8, monocyte chemoattractant protein 1, and leukotriene B4
    J Biomed Mater Res A, 74 (2), 230-6
    DOI 10.1002/jbm.a.30372, PubMed 15962266
  7. Lappegård KT, Riesenfeld J, Brekke OL, Bergseth G, Lambris JD, Mollnes TE (2005)
    Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production
    Ann Thorac Surg, 79 (3), 917-23
    DOI 10.1016/j.athoracsur.2004.08.015, PubMed 15734405
  8. Sørlie D, Wisborg T, Wählby L, Wilskow A, Mollnes TE, Gamnes J, Arnesen E (2005)
    [A programme for boosting medical research in North Norway, 1992-2001]
    Tidsskr Nor Laegeforen, 125 (4), 449-50
    PubMed 15742020
  9. Trøseid M, Lappegård KT, Mollnes TE, Arnesen H, Seljeflot I (2005)
    Changes in serum levels of E-selectin correlate to improved glycaemic control and reduced obesity in subjects with the metabolic syndrome
    Scand J Clin Lab Invest, 65 (4), 283-90
    DOI 10.1080/00365510510013811, PubMed 16076683

Publications 2004

  1. Bossi F, Fischetti F, Pellis V, Bulla R, Ferrero E, Mollnes TE, Regoli D, Tedesco F (2004)
    Platelet-activating factor and kinin-dependent vascular leakage as a novel functional activity of the soluble terminal complement complex
    J Immunol, 173 (11), 6921-7
    DOI 10.4049/jimmunol.173.11.6921, PubMed 15557188
  2. Castellheim A, Pharo A, Fung M, Saugstad OD, Mollnes TE (2004)
    Complement C5a is a key mediator of meconium-induced neutrophil activation
    Pediatr Res, 57 (2), 242-7
    DOI 10.1203/01.PDR.0000150725.78971.30, PubMed 15585680
  3. Harboe M, Ulvund G, Vien L, Fung M, Mollnes TE (2004)
    The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation
    Clin Exp Immunol, 138 (3), 439-46
    DOI 10.1111/j.1365-2249.2004.02627.x, PubMed 15544620
  4. Heggelund L, Flo T, Berg K, Lien E, Mollnes TE, Ueland T, Aukrust P, Espevik T, Frøland SS (2004)
    Soluble toll-like receptor 2 in HIV infection: association with disease progression
    AIDS, 18 (18), 2437-9
    PubMed 15622324
  5. Hoel TN, Videm V, Baksaas ST, Mollnes TE, Brosstad F, Svennevig JL (2004)
    Comparison of a Duraflo II-coated cardiopulmonary bypass circuit and a trillium-coated oxygenator during open-heart surgery
    Perfusion, 19 (3), 177-84
    DOI 10.1191/0267659104pf737oa, PubMed 15298426
  6. Lappegård KT, Fung M, Bergseth G, Riesenfeld J, Lambris JD, Videm V, Mollnes TE (2004)
    Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation
    Ann Thorac Surg, 77 (3), 932-41
    DOI 10.1016/S0003-4975(03)01519-4, PubMed 14992902
  7. Lappegård KT, Fung M, Bergseth G, Riesenfeld J, Mollnes TE (2004)
    Artificial surface-induced cytokine synthesis: effect of heparin coating and complement inhibition
    Ann Thorac Surg, 78 (1), 38-44; discussion 44-5
    DOI 10.1016/j.athoracsur.2004.02.005, PubMed 15223398
  8. Lappegård KT, Hvassing T, Mollnes TE (2004)
    Statin drugs do not affect serum complement activation in vitro
    Scand J Immunol, 60 (1-2), 178-83
    DOI 10.1111/j.0300-9475.2004.01439.x, PubMed 15238087
  9. Lindenskov PH, Castellheim A, Aamodt G, Saugstad OD, Mollnes TE (2004)
    Complement activation reflects severity of meconium aspiration syndrome in newborn pigs
    Pediatr Res, 56 (5), 810-7
    DOI 10.1203/01.PDR.0000141983.32466.2A, PubMed 15347770
  10. Pedersen ED, Waje-Andreassen U, Vedeler CA, Aamodt G, Mollnes TE (2004)
    Systemic complement activation following human acute ischaemic stroke
    Clin Exp Immunol, 137 (1), 117-22
    DOI 10.1111/j.1365-2249.2004.02489.x, PubMed 15196251
  11. Seelen MA, Roos A, Wieslander J, Mollnes TE, Sjöholm AG, Wurzner R, Loos M, Tedesco F, Sim RB, Garred P, Alexopoulos E, Turner MW, Daha MR (2004)
    Functional analysis of the classical, alternative, and MBL pathways of the complement system: standardization and validation of a simple ELISA
    J Immunol Methods, 296 (1-2), 187-98
    DOI 10.1016/j.jim.2004.11.016, PubMed 15680163
  12. Sprong T, Møller AS, Bjerre A, Wedege E, Kierulf P, van der Meer JW, Brandtzaeg P, van Deuren M, Mollnes TE (2004)
    Complement activation and complement-dependent inflammation by Neisseria meningitidis are independent of lipopolysaccharide
    Infect Immun, 72 (6), 3344-9
    DOI 10.1128/IAI.72.6.3344-3349.2004, PubMed 15155639
  13. Sund S, Reisaeter AV, Scott H, Mollnes TE, Hovig T (2004)
    Glomerular monocyte/macrophage influx correlates strongly with complement activation in 1-week protocol kidney allograft biopsies
    Clin Nephrol, 62 (2), 121-30
    DOI 10.5414/cnp62121, PubMed 15356969
  14. Trøseid M, Lappegård KT, Claudi T, Damås JK, Mørkrid L, Brendberg R, Mollnes TE (2004)
    Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome
    Eur Heart J, 25 (4), 349-55
    DOI 10.1016/j.ehj.2003.12.006, PubMed 14984925

Publications 2003

  1. Castellheim A, Lindenskov PH, Pharo A, Fung M, Saugstad OD, Mollnes TE (2003)
    Meconium is a potent activator of complement in human serum and in piglets
    Pediatr Res, 55 (2), 310-8
    DOI 10.1203/01.PDR.0000100902.76021.8E, PubMed 14605246
  2. Fiane AE, Videm V, Lingaas PS, Heggelund L, Nielsen EW, Geiran OR, Fung M, Mollnes TE (2003)
    Mechanism of complement activation and its role in the inflammatory response after thoracoabdominal aortic aneurysm repair
    Circulation, 108 (7), 849-56
    DOI 10.1161/01.CIR.0000084550.16565.01, PubMed 12900342
  3. Fung M, Lu M, Fure H, Sun W, Sun C, Shi NY, Dou Y, Su J, Swanson X, Mollnes TE (2003)
    Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage
    Clin Exp Immunol, 133 (2), 160-9
    DOI 10.1046/j.1365-2249.2003.02213.x, PubMed 12869020
  4. Heggelund L, Mollnes TE, Ueland T, Christophersen B, Aukrust P, Frøland SS (2003)
    Mannose-binding lectin in HIV infection: relation to disease progression and highly active antiretroviral therapy
    J Acquir Immune Defic Syndr, 32 (4), 354-61
    DOI 10.1097/00126334-200304010-00002, PubMed 12640191
  5. Kirschfink M, Mollnes TE (2003)
    Modern complement analysis
    Clin Diagn Lab Immunol, 10 (6), 982-9
    DOI 10.1128/cdli.10.6.982-989.2003, PubMed 14607856
  6. Mollnes TE (2003)
    Measurement of complement activation
    Methods Mol Biol, 225, 69-75
    DOI 10.1385/1-59259-374-7:69, PubMed 12769475
  7. Mollnes TE, Fiane AE (2003)
    Perspectives on complement in xenotransplantation
    Mol Immunol, 40 (2-4), 135-43
    DOI 10.1016/s0161-5890(03)00106-8, PubMed 12914819
  8. Risnes I, Ueland T, Aukrust P, Lundblad R, Baksaas ST, Mollnes TE, Svennevig JL (2003)
    Complement activation and cytokine and chemokines release during mediastinitis
    Ann Thorac Surg, 75 (3), 981-5
    DOI 10.1016/s0003-4975(02)04556-3, PubMed 12645727
  9. Risnes I, Ueland T, Lundblad R, Mollnes TE, Baksaas ST, Aukrust P, Svennevig JL (2003)
    Changes in the cytokine network and complement parameters during open heart surgery
    Interact Cardiovasc Thorac Surg, 2 (1), 19-24
    DOI 10.1016/S1569-9293(02)00088-9, PubMed 17669979
  10. Solheim BG, Flesland O, Brosstad F, Mollnes TE, Seghatchian J (2003)
    Improved preservation of coagulation factors after pre-storage leukocyte depletion of whole blood
    Transfus Apher Sci, 29 (2), 133-9
    DOI 10.1016/S1473-0502(03)00117-4, PubMed 12941351
  11. Sprong T, Brandtzaeg P, Fung M, Pharo AM, Høiby EA, Michaelsen TE, Aase A, van der Meer JW, van Deuren M, Mollnes TE (2003)
    Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis
    Blood, 102 (10), 3702-10
    DOI 10.1182/blood-2003-03-0703, PubMed 12881318
  12. Sund S, Hovig T, Reisaeter AV, Scott H, Bentdal Ø, Mollnes TE (2003)
    Complement activation in early protocol kidney graft biopsies after living-donor transplantation
    Transplantation, 75 (8), 1204-13
    DOI 10.1097/01.TP.0000062835.30165.2C, PubMed 12717204
  13. Tølløfsrud S, Noddeland H, Svennevig JL, Bentsen G, Mollnes TE, Solheim BG (2003)
    Universal fresh frozen plasma (Uniplas): a safe product in open-heart surgery
    Intensive Care Med, 29 (10), 1736-43
    DOI 10.1007/s00134-003-1952-3, PubMed 12955185

Publications 2002

  1. Bjerre A, Brusletto B, Mollnes TE, Fritzsønn E, Rosenqvist E, Wedege E, Namork E, Kierulf P, Brandtzaeg P (2002)
    Complement activation induced by purified Neisseria meningitidis lipopolysaccharide (LPS), outer membrane vesicles, whole bacteria, and an LPS-free mutant
    J Infect Dis, 185 (2), 220-8
    DOI 10.1086/338269, PubMed 11807696
  2. Evgenov OV, Evgenov NV, Mollnes TE, Bjertnaes LJ (2002)
    Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep
    Eur Respir J, 20 (4), 957-64
    DOI 10.1183/09031936.02.00932001, PubMed 12412689
  3. Fiane AE, Geiran OR, Mollnes TE (2002)
    [Ethical aspects of xenotransplantation]
    Tidsskr Nor Laegeforen, 122 (4), 397-400
    PubMed 11915670
  4. Mollnes TE, Brekke OL, Fung M, Fure H, Christiansen D, Bergseth G, Videm V, Lappegård KT, Köhl J, Lambris JD (2002)
    Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation
    Blood, 100 (5), 1869-77
    PubMed 12176911
  5. Mollnes TE, Fiane AE (2002)
    Role of complement in xenotransplantation
    Allergy, 57 Suppl 72, 75-8
    DOI 10.1034/j.1398-9995.57.s72.10.x, PubMed 12144560
  6. Mollnes TE, Song WC, Lambris JD (2002)
    Complement in inflammatory tissue damage and disease
    Trends Immunol, 23 (2), 61-4
    DOI 10.1016/s1471-4906(01)02129-9, PubMed 11929126
  7. Nielsen EW, Mollnes TE, Harlan JM, Winn RK (2002)
    C1-inhibitor reduces the ischaemia-reperfusion injury of skeletal muscles in mice after aortic cross-clamping
    Scand J Immunol, 56 (6), 588-92
    DOI 10.1046/j.1365-3083.2002.01173.x, PubMed 12472670
  8. Saethre M, Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Platt JL, Mollnes TE (2002)
    Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies
    Xenotransplantation, 9 (5), 350-8
    DOI 10.1034/j.1399-3089.2002.01094.x, PubMed 12199866
  9. Scholz T, Solberg R, Okkenhaug C, Videm V, Gallimore MJ, Mathisen O, Mollnes TE, Bergan A, Søreide O, Klintmalm GB, Aasen AO (2002)
    The significance of heparin-coated veno-venous bypass circuits in liver transplantation
    Perfusion, 17 (1), 45-50
    DOI 10.1191/0267659102pf523oa, PubMed 11817529

Publications 2001

  1. Aukrust P, Gullestad L, Lappegård KT, Ueland T, Aass H, Wikeby L, Simonsen S, Frøland SS, Mollnes TE (2001)
    Complement activation in patients with congestive heart failure: effect of high-dose intravenous immunoglobulin treatment
    Circulation, 104 (13), 1494-500
    DOI 10.1161/hc3801.096353, PubMed 11571242
  2. Kirschfink M, Mollnes TE (2001)
    C1-inhibitor: an anti-inflammatory reagent with therapeutic potential
    Expert Opin Pharmacother, 2 (7), 1073-83
    DOI 10.1517/14656566.2.7.1073, PubMed 11583058
  3. Lamark T, Ingebrigtsen M, Bjørnstad C, Melkko T, Mollnes TE, Nielsen EW (2001)
    Expression of active human C1 inhibitor serpin domain in Escherichia coli
    Protein Expr Purif, 22 (2), 349-58
    DOI 10.1006/prep.2001.1445, PubMed 11437612
  4. Mellembakken JR, Høgåsen K, Mollnes TE, Hack CE, Abyholm T, Videm V (2001)
    Increased systemic activation of neutrophils but not complement in preeclampsia
    Obstet Gynecol, 97 (3), 371-4
    DOI 10.1016/s0029-7844(00)01179-0, PubMed 11239639
  5. Scholz T, Solberg R, Okkenhaug C, Videm V, Gallimore MJ, Mathisen O, Pedersen T, Mollnes TE, Bergan A, Søreide O, Klintmalm GB, Aasen AO (2001)
    Veno-venous bypass in liver transplantation: heparin-coated perfusion circuits reduce the activation of humoral defense systems in an in vitro model
    Perfusion, 16 (4), 285-92
    DOI 10.1177/026765910101600404, PubMed 11486847
  6. Sølvik UO, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Mollnes TE (2001)
    C1-inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells
    Transplant Proc, 33 (1-2), 789-90
    DOI 10.1016/s0041-1345(00)02256-9, PubMed 11267073
  7. Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Lambris JD, Fung M, Thorsby E, Mollnes TE (2001)
    Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated
    Transplantation, 72 (12), 1967-73
    DOI 10.1097/00007890-200112270-00017, PubMed 11773897
  8. Ulvestad E, Berentsen S, Mollnes TE (2001)
    Acute phase haemolysis in chronic cold agglutinin disease
    Scand J Immunol, 54 (1-2), 239-42
    DOI 10.1046/j.1365-3083.2001.00960.x, PubMed 11439172

Publications 2000

  1. Bergseth G, Lappegård KT, Videm V, Mollnes TE (2000)
    A novel enzyme immunoassay for plasma thrombospondin. Comparison with beta-thromboglobulin as platelet activation marker in vitro and in vivo
    Thromb Res, 99 (1), 41-50
    DOI 10.1016/s0049-3848(00)00226-7, PubMed 10904102
  2. Fiane AE, Mollnes TE, Degré M (2000)
    Pig endogenous retrovirus--a threat to clinical xenotransplantation?
    APMIS, 108 (4), 241-50
    DOI 10.1034/j.1600-0463.2000.d01-51.x, PubMed 10843410
  3. Fiane AE, Videm V, Lambris JD, Geiran OR, Svennevig JL, Mollnes TE (2000)
    Modulation of fluid-phase complement activation inhibits hyperacute rejection in a porcine-to-human xenograft model
    Transplant Proc, 32 (5), 899-900
    DOI 10.1016/s0041-1345(00)01028-9, PubMed 10936264
  4. Myhr KM, Sadallah S, Mollnes TE, Meri S, Nyland HI, Schifferli J, Vedeler CA (2000)
    Interferon-alpha2a effects on complement activation and regulation in MS patients
    Acta Neurol Scand, 101 (1), 30-5
    DOI 10.1034/j.1600-0404.2000.00013.x, PubMed 10660149
  5. Odegård A, Lundbom J, Myhre HO, Hatlinghus S, Bergh K, Waage A, Bjerve KS, Mollnes TE, Aadahl P, Lie TA, Videm V (2000)
    The inflammatory response following treatment of abdominal aortic aneurysms: a comparison between open surgery and endovascular repair
    Eur J Vasc Endovasc Surg, 19 (5), 536-44
    DOI 10.1053/ejvs.1999.1092, PubMed 10828237
  6. Olsson P, Sanchez J, Mollnes TE, Riesenfeld J (2000)
    On the blood compatibility of end-point immobilized heparin
    J Biomater Sci Polym Ed, 11 (11), 1261-73
    DOI 10.1163/156856200744192, PubMed 11263812

Publications 1999

  1. Baksaas ST, Flom-Halvorsen HI, Ovrum E, Videm V, Mollnes TE, Brosstad F, Svennevig JL (1999)
    Leucocyte filtration during cardiopulmonary reperfusion in coronary artery bypass surgery
    Perfusion, 14 (2), 107-17
    DOI 10.1177/026765919901400204, PubMed 10338322
  2. Baksaas ST, Videm V, Fosse E, Karlsen H, Pedersen T, Mollnes TE, Hagve TA, Svennevig JL (1999)
    In vitro evaluation of new surface coatings for extracorporeal circulation
    Perfusion, 14 (1), 11-9
    DOI 10.1177/026765919901400103, PubMed 10074642
  3. Baksaas ST, Videm V, Pedersen T, Karlsen H, Mollnes TE, Brosstad F, Svennevig JL (1999)
    Comparison of three oxygenator-coated and one total-circuit-coated extracorporeal devices
    Perfusion, 14 (2), 119-27
    DOI 10.1177/026765919901400205, PubMed 10338323
  4. Fiane AE, Mollnes TE (1999)
    [Transplantation from animal to man]
    Tidsskr Nor Laegeforen, 119 (28), 4213-8
    PubMed 10668386
  5. Fiane AE, Mollnes TE, Videm V, Hovig T, Høgåsen K, Mellbye OJ, Spruce L, Moore WT, Sahu A, Lambris JD (1999)
    Prolongation of ex vivo-perfused pig xenograft survival by the complement inhibitor Compstatin
    Transplant Proc, 31 (1-2), 934-5
    DOI 10.1016/s0041-1345(98)01844-2, PubMed 10083413
  6. Fiane AE, Mollnes TE, Videm V, Hovig T, Høgåsen K, Mellbye OJ, Spruce L, Moore WT, Sahu A, Lambris JD (1999)
    Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts
    Xenotransplantation, 6 (1), 52-65
    DOI 10.1034/j.1399-3089.1999.00007.x, PubMed 10355733
  7. Fiane AE, Videm V, Johansen HT, Mellbye OJ, Nielsen EW, Mollnes TE (1999)
    C1-inhibitor attenuates hyperacute rejection and inhibits complement, leukocyte and platelet activation in an ex vivo pig-to-human perfusion model
    Immunopharmacology, 42 (1-3), 231-43
    DOI 10.1016/s0162-3109(99)00008-9, PubMed 10408384
  8. Fiane AE, Videm V, Mollnes TE, Høgâsen K, Hovig T (1999)
    Inhibition of platelet aggregation by the GPIIb/IIIa antagonist reopro does not significantly prolong xenograft survival in an ex vivo model
    Transpl Int, 12 (5), 323-33
    DOI 10.1007/s001470050235, PubMed 10551997
  9. Krohn CD, Reikerås O, Mollnes TE (1999)
    Complement activation and increased systemic and pulmonary vascular resistance indices during infusion of postoperatively drained untreated blood
    Br J Anaesth, 82 (1), 47-51
    DOI 10.1093/bja/82.1.47, PubMed 10325835
  10. Mollnes TE, Fiane AE (1999)
    Xenotransplantation: how to overcome the complement obstacle?
    Mol Immunol, 36 (4-5), 269-76
    DOI 10.1016/s0161-5890(99)00050-4, PubMed 10403480
  11. Mollnes TE, Haga HJ, Brun JG, Nielsen EW, Sjöholm A, Sturfeldt G, Mårtensson U, Bergh K, Rekvig OP (1999)
    Complement activation in patients with systemic lupus erythematosus without nephritis
    Rheumatology (Oxford), 38 (10), 933-40
    DOI 10.1093/rheumatology/38.10.933, PubMed 10534542
  12. Mollnes TE, Videm V, Christiansen D, Bergseth G, Riesenfeld J, Hovig T (1999)
    Platelet compatibility of an artificial surface modified with functionally active heparin
    Thromb Haemost, 82 (3), 1132-6
    PubMed 10494777
  13. Neeleman C, Geelen SP, Aerts PC, Daha MR, Mollnes TE, Roord JJ, Posthuma G, van Dijk H, Fleer A (1999)
    Resistance to both complement activation and phagocytosis in type 3 pneumococci is mediated by the binding of complement regulatory protein factor H
    Infect Immun, 67 (9), 4517-24
    DOI 10.1128/IAI.67.9.4517-4524.1999, PubMed 10456894
  14. Videm V, Mollnes TE, Bergh K, Fosse E, Mohr B, Hagve TA, Aasen AO, Svennevig JL (1999)
    Heparin-coated cardiopulmonary bypass equipment. II. Mechanisms for reduced complement activation in vivo
    J Thorac Cardiovasc Surg, 117 (4), 803-9
    DOI 10.1016/S0022-5223(99)70302-8, PubMed 10096977
  15. Videm V, Mollnes TE, Fosse E, Mohr B, Bergh K, Hagve TA, Aasen AO, Svennevig JL (1999)
    Heparin-coated cardiopulmonary bypass equipment. I. Biocompatibility markers and development of complications in a high-risk population
    J Thorac Cardiovasc Surg, 117 (4), 794-802
    DOI 10.1016/s0022-5223(99)70301-6, PubMed 10096976

Publications 1998

  1. Arnestad JP, Hyllner M, Bengtson JP, Tylman M, Mollnes TE, Bengtsson A (1998)
    Removal of activated complement from shed blood: comparison of high- and low-dilutional haemofiltration
    Acta Anaesthesiol Scand, 42 (7), 811-5
    DOI 10.1111/j.1399-6576.1998.tb05327.x, PubMed 9698958
  2. Baksaas ST, Videm V, Mollnes TE, Tølløfsrud S, Hetland G, Pedersen T, Svennevig JL (1998)
    Leucocyte filtration during cardiopulmonary bypass hardly changed leucocyte counts and did not influence myeloperoxidase, complement, cytokines or platelets
    Perfusion, 13 (6), 429-36
    DOI 10.1177/026765919801300606, PubMed 9881390
  3. Bengtsson A, Redl H, Schlag G, Högåsen K, Götze O, Mollnes TE (1998)
    Anti-TNF treatment of baboons with sepsis reduces TNF-alpha, IL-6 and IL-8, but not the degree of complement activation
    Scand J Immunol, 48 (5), 509-14
    DOI 10.1046/j.1365-3083.1998.00433.x, PubMed 9822260
  4. Fiane AE, Videm V, Foerster A, Scholz T, Perdersen TH, Karlsen H, Svennevig JL, Geiran OR, Aasen AO, Mollnes TE (1998)
    An ex vivo perfusion model to evaluate hyperacute rejection in a discordant pig-to-human combination
    Eur Surg Res, 30 (5), 341-51
    DOI 10.1159/000008597, PubMed 9731103
  5. Fiane AE, Videm V, Mellbye OJ, Foerster A, Geiran OR, Gladhaug IP, Svennevig JL, Mollnes TE (1998)
    Immunoglobulin prolongs survival of pig kidneys perfused ex vivo with human blood
    Scand J Immunol, 47 (6), 568-74
    DOI 10.1046/j.1365-3083.1998.00341.x, PubMed 9652825
  6. Fosse E, Pillgram-Larsen J, Svennevig JL, Nordby C, Skulberg A, Mollnes TE, Abdelnoor M (1998)
    Complement activation in injured patients occurs immediately and is dependent on the severity of the trauma
    Injury, 29 (7), 509-14
    DOI 10.1016/s0020-1383(98)00113-2, PubMed 10193492
  7. Hetland G, Mollnes TE, Bergh K, Høgåsen K, Bergerud UE, Solheim BG (1998)
    Effect of filtration and storage of platelet concentrates on the production of the chemotaxins C5a, interleukin 8, tumor necrosis factor alpha, and leukotriene B4
    Transfusion, 38 (1), 16-23
    DOI 10.1046/j.1537-2995.1998.38198141493.x, PubMed 9482389
  8. Høgåsen K, Mollnes TE, Nürnberger W, Pausa M, Fukumori Y, Tedesco F (1998)
    Characterization of soluble terminal complement complex assembled in C8beta-deficient plasma and serum
    Scand J Immunol, 48 (3), 261-8
    DOI 10.1046/j.1365-3083.1998.00390.x, PubMed 9743210
  9. Krohn CD, Reikerås O, Mollnes TE, Aasen AO (1998)
    Complement activation and release of interleukin-6 and tumour necrosis factor-alpha in drained and systemic blood after major orthopaedic surgery
    Eur J Surg, 164 (2), 103-8
    DOI 10.1080/110241598750004742, PubMed 9537716
  10. Mollnes TE (1998)
    Complement and biocompatibility
    Vox Sang, 74 Suppl 2, 303-7
    DOI 10.1111/j.1423-0410.1998.tb05435.x, PubMed 9704460
  11. Mollnes TE, Høgåsen K, De Carolis C, Vaquero E, Nielsen EW, Fontana L, Perricone R (1998)
    High-dose intravenous immunoglobulin treatment activates complement in vivo
    Scand J Immunol, 48 (3), 312-7
    DOI 10.1046/j.1365-3083.1998.00386.x, PubMed 9743219
  12. Nielsen EW, Fure H, Winge P, Mollnes TE (1998)
    Identification of a C-->T mutation in the reactive-site coding region of the C1-inhibitor gene and its detection by an improved mutation-specific polymerase chain reaction method
    Scand J Immunol, 47 (3), 273-6
    DOI 10.1046/j.1365-3083.1998.00290.x, PubMed 9519866
  13. Nordang L, Laurent C, Mollnes TE (1998)
    Complement activation in sudden deafness
    Arch Otolaryngol Head Neck Surg, 124 (6), 633-6
    DOI 10.1001/archotol.124.6.633, PubMed 9639471
  14. Solheim BG, Bergerud UE, Kjeldsen-Kragh J, Brosstad F, Mollnes TE, Högman CF, Eriksson L, Schutz R (1998)
    Improved blood preservation with 0.5CPD erythro-sol. Coagulation factor VIII activity and erythrocyte quality after delayed separation of blood
    Vox Sang, 74 (3), 168-75
    DOI 10.1046/j.1423-0410.1998.7430168.x, PubMed 9595644

Publications 1997

  1. Baksaas ST, Videm V, Mollnes TE, Pedersen T, Karlsen H, Svennevig JL (1997)
    Effects on complement, granulocytes and platelets of a leukocyte-depletion filter during in vitro extracorporeal circulation
    Scand Cardiovasc J, 31 (2), 73-7
    DOI 10.3109/14017439709058072, PubMed 9211593
  2. Fosse E, Thelin S, Svennevig JL, Jansen P, Mollnes TE, Hack E, Venge P, Moen O, Brockmeier V, Dregelid E, Haldén E, Hagman L, Videm V, Pedersen T, Mohr B (1997)
    Duraflo II coating of cardiopulmonary bypass circuits reduces complement activation, but does not affect the release of granulocyte enzymes : a European multicentre study
    Eur J Cardiothorac Surg, 11 (2), 320-7
    DOI 10.1016/s1010-7940(96)01062-7, PubMed 9080162
  3. Fure H, Nielsen EW, Hack CE, Mollnes TE (1997)
    A neoepitope-based enzyme immunoassay for quantification of C1-inhibitor in complex with C1r and C1s
    Scand J Immunol, 46 (6), 553-7
    DOI 10.1046/j.1365-3083.1997.d01-168.x, PubMed 9420617
  4. Garred P, Mollnes TE (1997)
    Immobilized heparin inhibits the increase in leukocyte surface expression of adhesion molecules
    Artif Organs, 21 (4), 293-9
    DOI 10.1111/j.1525-1594.1997.tb00364.x, PubMed 9096801
  5. Hetland G, Moen O, Bergh K, Högäsen K, Hack CE, Mollnes TE, Fosse E (1997)
    Both plasma- and leukocyte-associated C5a are essential for assessment of C5a generation in vivo
    Ann Thorac Surg, 63 (4), 1076-80
    DOI 10.1016/s0003-4975(96)01255-6, PubMed 9124908
  6. Homann C, Varming K, Høgåsen K, Mollnes TE, Graudal N, Thomsen AC, Garred P (1997)
    Acquired C3 deficiency in patients with alcoholic cirrhosis predisposes to infection and increased mortality
    Gut, 40 (4), 544-9
    DOI 10.1136/gut.40.4.544, PubMed 9176087
  7. Moen O, Høgåsen K, Fosse E, Dregelid E, Brockmeier V, Venge P, Harboe M, Mollnes TE (1997)
    Attenuation of changes in leukocyte surface markers and complement activation with heparin-coated cardiopulmonary bypass
    Ann Thorac Surg, 63 (1), 105-11
    DOI 10.1016/s0003-4975(96)00743-6, PubMed 8993250
  8. Mollnes TE (1997)
    Biocompatibility: complement as mediator of tissue damage and as indicator of incompatibility
    Exp Clin Immunogenet, 14 (1), 24-9
    PubMed 9187920
  9. Mollnes TE, Andreassen IH, Høgåsen K, Hack CE, Harboe M (1997)
    Effect of whole and fractionated intravenous immunoglobulin on complement in vitro
    Mol Immunol, 34 (10), 719-29
    DOI 10.1016/s0161-5890(97)00091-6, PubMed 9430199
  10. Pedersen TH, Videm V, Svennevig JL, Karlsen H, Ostbakk RW, Jensen O, Mollnes TE (1997)
    Extracorporeal membrane oxygenation using a centrifugal pump and a servo regulator to prevent negative inlet pressure
    Ann Thorac Surg, 63 (5), 1333-9
    DOI 10.1016/s0003-4975(97)00098-2, PubMed 9146324
  11. Samdal F, Mollnes TE, Amland PF, Truedsson L (1997)
    Modest release of adipsin/factor D by liposuction when using the superwet or tumescent technique
    Plast Reconstr Surg, 99 (6), 1591-4; discussion 1595-6
    DOI 10.1097/00006534-199705000-00017, PubMed 9145127

Publications 1996

  1. Bengtsson A, Redl H, Schlag G, Mollnes TE, Högåsen K (1996)
    Effects on complement activation and cytokine (TNF-alpha and IL-8) release of infusion of anti-TNF-antibodies or a xanthine derivative (HWA 138) in septic baboons
    Acta Anaesthesiol Scand, 40 (2), 244-9
    DOI 10.1111/j.1399-6576.1996.tb04427.x, PubMed 8848926
  2. Brandtzaeg P, Høgåsen K, Kierulf P, Mollnes TE (1996)
    The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activation
    J Infect Dis, 173 (3), 647-55
    DOI 10.1093/infdis/173.3.647, PubMed 8627028
  3. Bringeland EA, Ramstad K, Nielsen EW, Andersen L, Amundsen W, Mollnes TE (1996)
    [Reduced blood utilization in hip arthroplasty. Introduction of a blood preservation program]
    Tidsskr Nor Laegeforen, 116 (1), 30-3
    PubMed 8553331
  4. Gong J, Larsson R, Ekdahl KN, Mollnes TE, Nilsson U, Nilsson B (1996)
    Tubing loops as a model for cardiopulmonary bypass circuits: both the biomaterial and the blood-gas phase interfaces induce complement activation in an in vitro model
    J Clin Immunol, 16 (4), 222-9
    DOI 10.1007/BF01541228, PubMed 8840224
  5. Høgåsen K, Homann C, Mollnes TE, Graudal N, Høgåsen AK, Hasselqvist P, Thomsen AC, Garred P (1996)
    Serum clusterin and vitronectin in alcoholic cirrhosis
    Liver, 16 (2), 140-6
    DOI 10.1111/j.1600-0676.1996.tb00719.x, PubMed 8740849
  6. Mellbye OJ, Shen Y, Høgåsen K, Mollnes TE, Førre O (1996)
    Adhesion molecule expression and complement activation in vessel walls in synovial tissue from patients with chronic inflammatory joint disease
    Clin Rheumatol, 15 (5), 441-7
    DOI 10.1007/BF02229640, PubMed 8894356
  7. Moen O, Fosse E, Bråten J, Andersson C, Høgåsen K, Mollnes TE, Venge P, Kierulf P (1996)
    Differences in blood activation related to roller/centrifugal pumps and heparin-coated/uncoated surfaces in a cardiopulmonary bypass model circuit
    Perfusion, 11 (2), 113-23
    DOI 10.1177/026765919601100205, PubMed 8740352
  8. Moen O, Fosse E, Dregelid E, Brockmeier V, Andersson C, Høgåsen K, Venge P, Mollnes TE, Kierulf P (1996)
    Centrifugal pump and heparin coating improves cardiopulmonary bypass biocompatibility
    Ann Thorac Surg, 62 (4), 1134-40
    DOI 10.1016/0003-4975(96)00492-4, PubMed 8823102
  9. Mollnes TE, Harboe M (1996)
    Clinical immunology
    BMJ, 312 (7044), 1465-9
    DOI 10.1136/bmj.312.7044.1465, PubMed 8664630
  10. Nielsen EW, Gran JT, Straume B, Mellbye OJ, Johansen HT, Mollnes TE (1996)
    Hereditary angio-oedema: new clinical observations and autoimmune screening, complement and kallikrein-kinin analyses
    J Intern Med, 239 (2), 119-30
    DOI 10.1046/j.1365-2796.1996.418764000.x, PubMed 8568479
  11. Nielsen EW, Johansen HT, Høgåsen K, Wuillemin W, Hack CE, Mollnes TE (1996)
    Activation of the complement, coagulation, fibrinolytic and kallikrein-kinin systems during attacks of hereditary angioedema
    Scand J Immunol, 44 (2), 185-92
    DOI 10.1046/j.1365-3083.1996.d01-298.x, PubMed 8711433
  12. Nielsen EW, Johansen HT, Høgåsen K, Wuillemin W, Hack CE, Mollnes TE (1996)
    Activation of the complement, coagulation, fibrinolytic and kallikrein-kinin systems during attacks of hereditary angioedema
    Immunopharmacology, 33 (1-3), 359-60
    DOI 10.1016/0162-3109(96)00085-9, PubMed 8856186
  13. Ovrum E, Fosse E, Mollnes TE, Am Holen E, Tangen G, Abdelnoor M, Ringdal MA, Oystese R, Venge P (1996)
    Complete heparin-coated cardiopulmonary bypass and low heparin dose reduce complement and granulocyte activation
    Eur J Cardiothorac Surg, 10 (1), 54-60
    DOI 10.1016/s1010-7940(96)80266-1, PubMed 8776186
  14. Radillo O, Nocera A, Leprini A, Barocci S, Mollnes TE, Pocecco M, Pausa M, Valente U, Betterle C, Tedesco F (1996)
    Complement-fixing islet cell antibodies in type-1 diabetes can trigger the assembly of the terminal complement complex on human islet cells and are potentially cytotoxic
    Clin Immunol Immunopathol, 79 (3), 217-23
    DOI 10.1006/clin.1996.0071, PubMed 8635278
  15. Svennevig JL, Tølløfsrud S, Kongsgaard U, Noddeland H, Mohr B, Ozer M, Mollnes TE (1996)
    Complement activation during and after open-heart surgery is only marginally affected by the choice of fluid for volume replacement
    Perfusion, 11 (4), 326-32
    DOI 10.1177/026765919601100405, PubMed 8884861
  16. Saatvedt K, Lindberg H, Geiran OR, Michelsen S, Pedersen T, Seem E, Mollnes TE (1996)
    Ultrafiltration after cardiopulmonary bypass in children: effects on hemodynamics, cytokines and complement
    Cardiovasc Res, 31 (4), 596-602
    PubMed 8689651
  17. Saatvedt K, Lindberg H, Michelsen S, Mollnes TE (1996)
    Release of interleukin 6 and activation of complement during and after paediatric cardiopulmonary bypass. Effect of autotransfusion of shed mediastinal blood and ultrafiltration
    Cytokine, 8 (5), 417-20
    DOI 10.1006/cyto.1996.0057, PubMed 8726671

Publications 1995

  1. Abrahamsen TG, Mollnes TE, Vandvik B (1995)
    Intrathecal immune response in neonatal Flavobacterium meningosepticum meningitis
    Biol Neonate, 68 (2), 153-6
    DOI 10.1159/000244231, PubMed 8534775
  2. Fiane AE, Videm V, Scholz T, Pedersen T, Karlsen H, Geiran O, Foerster A, Mollnes T, Aasen AO, Svennevig J (1995)
    Ex vivo model for xenotransplantation
    Transplant Proc, 27 (6), 3560-1
    PubMed 8540102
  3. Høgåsen K, Jansen JH, Mollnes TE, Hovdenes J, Harboe M (1995)
    Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency
    J Clin Invest, 95 (3), 1054-61
    DOI 10.1172/JCI117751, PubMed 7883953
  4. Høgåsen K, Mollnes TE, Harboe M, Götze O, Hammer HB, Oppermann M (1995)
    Terminal complement pathway activation and low lysis inhibitors in rheumatoid arthritis synovial fluid
    J Rheumatol, 22 (1), 24-8
    PubMed 7535360
  5. Kjeldsen-Kragh J, Mellbye OJ, Haugen M, Mollnes TE, Hammer HB, Sioud M, Førre O (1995)
    Changes in laboratory variables in rheumatoid arthritis patients during a trial of fasting and one-year vegetarian diet
    Scand J Rheumatol, 24 (2), 85-93
    DOI 10.3109/03009749509099290, PubMed 7747149
  6. Kuroki K, Roy S, Laerum F, Mollnes TE, Solheim BG, Videm V (1995)
    Complement activation by angiographic catheters in vitro
    J Vasc Interv Radiol, 6 (5), 819-26
    DOI 10.1016/s1051-0443(95)71193-9, PubMed 8541691
  7. Moen O, Fosse E, Brockmeier V, Andersson C, Mollnes TE, Høgåsen K, Venge P (1995)
    Disparity in blood activation by two different heparin-coated cardiopulmonary bypass systems
    Ann Thorac Surg, 60 (5), 1317-23
    DOI 10.1016/0003-4975(95)00777-i, PubMed 8526620
  8. Mollnes TE, Høgåsen K, Hoaas BF, Michaelsen TE, Garred P, Harboe M (1995)
    Inhibition of complement-mediated red cell lysis by immunoglobulins is dependent on the IG isotype and its C1 binding properties
    Scand J Immunol, 41 (5), 449-56
    DOI 10.1111/j.1365-3083.1995.tb03591.x, PubMed 7725063
  9. Mollnes TE, Riesenfeld J, Garred P, Nordström E, Høgåsen K, Fosse E, Götze O, Harboe M (1995)
    A new model for evaluation of biocompatibility: combined determination of neoepitopes in blood and on artificial surfaces demonstrates reduced complement activation by immobilization of heparin
    Artif Organs, 19 (9), 909-17
    DOI 10.1111/j.1525-1594.1995.tb02450.x, PubMed 8687297
  10. Nielsen EW, Johansen HT, Gaudesen O, Osterud B, Olsen JO, Høgåsen K, Hack CE, Mollnes TE (1995)
    C3 is activated in hereditary angioedema, and C1/C1-inhibitor complexes rise during physical stress in untreated patients
    Scand J Immunol, 42 (6), 679-85
    DOI 10.1111/j.1365-3083.1995.tb03711.x, PubMed 8552992
  11. Ovrum E, Mollnes TE, Fosse E, Holen EA, Tangen G, Abdelnoor M, Ringdal MA, Oystese R, Venge P (1995)
    Complement and granulocyte activation in two different types of heparinized extracorporeal circuits
    J Thorac Cardiovasc Surg, 110 (6), 1623-32
    DOI 10.1016/s0022-5223(95)70023-4, PubMed 8523872
  12. Ovrum E, Mollnes TE, Fosse E, Holen EA, Tangen G, Ringdal MA, Videm V (1995)
    High and low heparin dose with heparin-coated cardiopulmonary bypass: activation of complement and granulocytes
    Ann Thorac Surg, 60 (6), 1755-61
    DOI 10.1016/0003-4975(95)00763-6, PubMed 8787476
  13. Riesenfeld J, Olsson P, Sanchez J, Mollnes TE (1995)
    Surface modification with functionally active heparin
    Med Device Technol, 6 (2), 24-31
    PubMed 10155375
  14. Røger M, Høgåsen K, Holme PA, Halstensen TS, Mollnes TE, Hovig T (1995)
    The Fluid-phase SC5b-9 Terminal Complement Complex Binds to the GPIIb/IIIa Complex of Thrombin-stimulated Human Blood Platelets Inhibiting Platelet Aggregation
    Platelets, 6 (3), 160-8
    DOI 10.3109/09537109509013269, PubMed 21043620
  15. Samdal F, Aasen AO, Mollnes TE, Høgåsen K, Amland PF (1995)
    Effect of syringe-assisted liposuction on activation of cascade systems and circulating cells when using the superwet or tumescent technique
    Ann Plast Surg, 35 (3), 242-8
    DOI 10.1097/00000637-199509000-00004, PubMed 7503516
  16. Saatvedt K, Lindberg H, Geiran OR, Michelsen S, Aasen AO, Pedersen T, Mollnes TE (1995)
    Complement activation and release of tumour necrosis factor alpha, interleukin-2, interleukin-6 and soluble tumour necrosis factor and interleukin-2 receptors during and after cardiopulmonary bypass in children
    Scand J Clin Lab Invest, 55 (1), 79-86
    DOI 10.3109/00365519509075381, PubMed 7624740

Publications 1994

  1. Busund R, Rønning G, Lindsetmo RO, Busund LT, Mollnes TE, Konopski Z, Revhaug A (1994)
    The effects of plasma and albumin infusion on organ function and sepsis markers in experimental gram-negative sepsis
    Shock, 2 (6), 402-7
    DOI 10.1097/00024382-199412000-00003, PubMed 7743369
  2. Fosse E, Moen O, Johnson E, Semb G, Brockmeier V, Mollnes TE, Fagerhol MK, Venge P (1994)
    Reduced complement and granulocyte activation with heparin-coated cardiopulmonary bypass
    Ann Thorac Surg, 58 (2), 472-7
    DOI 10.1016/0003-4975(94)92231-4, PubMed 8067851
  3. Høgåsen K, Mollnes TE, Brandtzaeg P (1994)
    Low levels of vitronectin and clusterin in acute meningococcal disease are closely associated with formation of the terminal-complement complex and the vitronectin-thrombin-antithrombin complex
    Infect Immun, 62 (11), 4874-80
    DOI 10.1128/iai.62.11.4874-4880.1994, PubMed 7523299
  4. Mellbye OJ, Mollnes TE, Steen LS (1994)
    IgG subclass distribution and complement activation ability of autoantibodies to neutrophil cytoplasmic antigens (ANCA)
    Clin Immunol Immunopathol, 70 (1), 32-9
    DOI 10.1006/clin.1994.1007, PubMed 8261667
  5. Moen O, Fosse E, Bråten J, Andersson C, Fagerhol MK, Venge P, Høgåsen K, Mollnes TE (1994)
    Roller and centrifugal pumps compared in vitro with regard to haemolysis, granulocyte and complement activation
    Perfusion, 9 (2), 109-17
    DOI 10.1177/026765919400900205, PubMed 7919596
  6. Mollnes TE, Fosse E (1994)
    The complement system in trauma-related and ischemic tissue damage: a brief review
    Shock, 2 (4), 301-10
    DOI 10.1097/00024382-199410000-00012, PubMed 7757525
  7. Nielsen EW, Johansen HT, Holt J, Mollnes TE (1994)
    C1 inhibitor and diagnosis of hereditary angioedema in newborns
    Pediatr Res, 35 (2), 184-7
    DOI 10.1203/00006450-199402000-00012, PubMed 8165053
  8. Nielsen EW, Johansen HT, Straume B, Mollnes TE (1994)
    Effect of time, temperature and additives on a functional assay of C1 inhibitor
    J Immunol Methods, 173 (2), 245-51
    DOI 10.1016/0022-1759(94)90303-4, PubMed 8046257
  9. Nielsen EW, Stenberg PA, Einarsen E, Johansen HT, Mollnes TE (1994)
    [Angioedema associated with ACE inhibitors]
    Tidsskr Nor Laegeforen, 114 (7), 804-6
    PubMed 8009499
  10. Røger M, Høgåsen K, Mollnes TE, Hovig T (1994)
    The Membrane Glycoprotein IIb/IIIa Complex Mediates Deposition of Thrombin-stimulated Blood Platelets on Polystyrene Plastic Under Static Conditions
    Platelets, 5 (2), 96-104
    DOI 10.3109/09537109409005519, PubMed 21043610
  11. Verduin CM, Jansze M, Hol C, Mollnes TE, Verhoef J, van Dijk H (1994)
    Differences in complement activation between complement-resistant and complement-sensitive Moraxella (Branhamella) catarrhalis strains occur at the level of membrane attack complex formation
    Infect Immun, 62 (2), 589-95
    DOI 10.1128/iai.62.2.589-595.1994, PubMed 8300216
  12. Videm V, Mollnes TE (1994)
    Human complement activation by polygeline and dextran 70
    Scand J Immunol, 39 (3), 314-20
    DOI 10.1111/j.1365-3083.1994.tb03377.x, PubMed 7510416

Publications 1993

  1. Bengtsson A, Redl H, Paul E, Schlag G, Mollnes TE, Davies J (1993)
    Complement and leukocyte activation in septic baboons
    Circ Shock, 39 (2), 83-8
    PubMed 8490996
  2. Garred P, Fosse E, Fagerhol MK, Videm V, Mollnes TE (1993)
    Calprotectin and complement activation during major operations with or without cardiopulmonary bypass
    Ann Thorac Surg, 55 (3), 694-9
    DOI 10.1016/0003-4975(93)90277-o, PubMed 8452432
  3. Garred P, Lyon H, Christoffersen P, Mollnes TE, Tranum-Jensen J (1993)
    Deposition of C3, the terminal complement complex and vitronectin in primary biliary cirrhosis and primary sclerosing cholangitis
    Liver, 13 (6), 305-10
    DOI 10.1111/j.1600-0676.1993.tb00650.x, PubMed 7507546
  4. Hetland G, Mollnes TE, Garred P (1993)
    The B chain, but not the A chain, of Ricinus communis activates human complement
    Cancer Lett, 75 (1), 59-63
    DOI 10.1016/0304-3835(93)90208-q, PubMed 8287382
  5. Høgåsen K, Mollnes TE, Tschopp J, Harboe M (1993)
    Quantitation of vitronectin and clusterin. Pitfalls and solutions in enzyme immunoassays for adhesive proteins
    J Immunol Methods, 160 (1), 107-15
    DOI 10.1016/0022-1759(93)90014-x, PubMed 7680696
  6. Jansen JH, Høgåsen K, Mollnes TE (1993)
    Extensive complement activation in hereditary porcine membranoproliferative glomerulonephritis type II (porcine dense deposit disease)
    Am J Pathol, 143 (5), 1356-65
    PubMed 8238252
  7. Jensen ET, Kharazmi A, Garred P, Kronborg G, Fomsgaard A, Mollnes TE, Høiby N (1993)
    Complement activation by Pseudomonas aeruginosa biofilms
    Microb Pathog, 15 (5), 377-88
    DOI 10.1006/mpat.1993.1087, PubMed 8015418
  8. Mollnes TE, Nielsen EW, Høgåsen K, Mellbye OJ (1993)
    [Complement analysis tests]
    Tidsskr Nor Laegeforen, 113 (2), 211-3
    PubMed 8430403
  9. Mollnes TE, Redl H, Høgåsen K, Bengtsson A, Garred P, Speilberg L, Lea T, Oppermann M, Götze O, Schlag G (1993)
    Complement activation in septic baboons detected by neoepitope-specific assays for C3b/iC3b/C3c, C5a and the terminal C5b-9 complement complex (TCC)
    Clin Exp Immunol, 91 (2), 295-300
    DOI 10.1111/j.1365-2249.1993.tb05898.x, PubMed 7679061
  10. Opdahl H, Mollnes TE, Naess O (1993)
    Effects of high dose E. coli lipopolysaccharide on rabbit lung function, and of subsequent addition of chemotactic granulocyte activators to their isolated, blood-perfused lungs
    Acta Anaesthesiol Scand, 37 (4), 334-42
    DOI 10.1111/j.1399-6576.1993.tb03725.x, PubMed 8322560
  11. Røger M, Høgåsen K, Solum NO, Mollnes TE, Hovig T (1993)
    Vitronectin inhibits blood platelet aggregation
    Platelets, 4 (4), 225-9
    DOI 10.3109/09537109309013222, PubMed 21043846
  12. Svennevig JL, Geiran OR, Karlsen H, Pedersen T, Mollnes TE, Kongsgard U, Frøysaker T (1993)
    Complement activation during extracorporeal circulation. In vitro comparison of Duraflo II heparin-coated and uncoated oxygenator circuits
    J Thorac Cardiovasc Surg, 106 (3), 466-72
    PubMed 8361189

Publications 1992

  1. Halstensen TS, Mollnes TE, Garred P, Fausa O, Brandtzaeg P (1992)
    Surface epithelium related activation of complement differs in Crohn's disease and ulcerative colitis
    Gut, 33 (7), 902-8
    DOI 10.1136/gut.33.7.902, PubMed 1379568
  2. Hetland G, Mollnes TE, Larsen J, Garred P (1992)
    Biocompatibility of white cell filters as evaluated by complement activation
    Transfusion, 32 (6), 557-61
    DOI 10.1046/j.1537-2995.1992.32692367201.x, PubMed 1502709
  3. Høgåsen K, Mollnes TE, Harboe M (1992)
    Heparin-binding properties of vitronectin are linked to complex formation as illustrated by in vitro polymerization and binding to the terminal complement complex
    J Biol Chem, 267 (32), 23076-82
    PubMed 1385412
  4. Røger M, Halstensen TS, Høgåsen K, Mollnes TE, Solum NO, Hovig T (1992)
    Platelets and vitronectin: immunocytochemical localization and platelet interaction with exogenously added vitronectin
    Nouv Rev Fr Hematol (1978), 34 (1), 47-54
    PubMed 1381819
  5. Videm V, Fosse E, Mollnes TE, Garred P, Svennevig JL (1992)
    Time for new concepts about measurement of complement activation by cardiopulmonary bypass?
    Ann Thorac Surg, 54 (4), 725-31
    DOI 10.1016/0003-4975(92)91018-5, PubMed 1417231
  6. Videm V, Svennevig JL, Fosse E, Semb G, Osterud A, Mollnes TE (1992)
    Reduced complement activation with heparin-coated oxygenator and tubings in coronary bypass operations
    J Thorac Cardiovasc Surg, 103 (4), 806-13
    PubMed 1548925

Publications 1991

  1. Brandtzaeg P, Waage A, Mollnes TE, Oktedalen O, Kierulf P (1991)
    Severe human septic shock involves more than tumor necrosis factor
    Prog Clin Biol Res, 367, 25-42
    PubMed 1924430
  2. Hetland G, Garred P, Mollnes TE, Størvold G (1991)
    The use of flow cytometry to detect the biosynthesis of complement components
    J Immunol Methods, 140 (2), 167-71
    DOI 10.1016/0022-1759(91)90367-o, PubMed 2066563
  3. Hetland G, Mollnes TE, Garred P (1991)
    Activation of complement during apheresis
    Clin Exp Immunol, 84 (3), 535-8
    PubMed 1904328
  4. Mellbye OJ, Førre O, Mollnes TE, Kvarnes L (1991)
    Immunopathology of subcutaneous rheumatoid nodules
    Ann Rheum Dis, 50 (12), 909-12
    DOI 10.1136/ard.50.12.909, PubMed 1768157
  5. Mollnes TE, Videm V, Götze O, Harboe M, Oppermann M (1991)
    Formation of C5a during cardiopulmonary bypass: inhibition by precoating with heparin
    Ann Thorac Surg, 52 (1), 92-7
    DOI 10.1016/0003-4975(91)91426-v, PubMed 2069469
  6. Mollnes TE, Videm V, Riesenfeld J, Garred P, Svennevig JL, Fosse E, Hogasen K, Harboe M (1991)
    Complement activation and bioincompatibility. The terminal complement complex for evaluation and surface modification with heparin for improvement of biomaterials
    Clin Exp Immunol, 86 Suppl 1 (Suppl 1), 21-6
    PubMed 1934602
  7. Olmez U, Garred P, Mollnes TE, Harboe M, Berntzen HB, Munthe E (1991)
    C3 activation products, C3 containing immune complexes, the terminal complement complex and native C9 in patients with rheumatoid arthritis
    Scand J Rheumatol, 20 (3), 183-9
    DOI 10.3109/03009749109103019, PubMed 2068540
  8. Siemssen PA, Garred P, Olsen J, Aasen AO, Mollnes TE (1991)
    Activation of complement, kallikrein-kinin, fibrinolysis and coagulation systems by urinary catheters. Effect of time and temperature in biocompatibility studies
    Br J Urol, 67 (1), 83-7
    DOI 10.1111/j.1464-410x.1991.tb15075.x, PubMed 1993281
  9. Videm V, Mollnes TE, Garred P, Svennevig JL (1991)
    Biocompatibility of extracorporeal circulation. In vitro comparison of heparin-coated and uncoated oxygenator circuits
    J Thorac Cardiovasc Surg, 101 (4), 654-60
    PubMed 2008104

Publications 1990

  1. Garred P, Hetland G, Mollnes TE, Stoervold G (1990)
    Synthesis of C3, C5, C6, C7, C8, and C9 by human fibroblasts
    Scand J Immunol, 32 (5), 555-60
    DOI 10.1111/j.1365-3083.1990.tb03196.x, PubMed 2270435
  2. Garred P, Michaelsen TE, Aase A, Mollnes TE (1990)
    C3, C4, and the terminal complement complex differ from C1q by binding predominantly to the antigenic part of solid phase immune complexes
    J Immunol, 144 (1), 198-203
    PubMed 2295791
  3. Garred P, Mollnes TE, Thorsteinsson L, Erlendsson K, Steinsson K (1990)
    Increased amounts of C4-containing immune complexes and inefficient activation of C3 and the terminal complement pathway in a patient with homozygous C2 deficiency and systemic lupus erythematosus
    Scand J Immunol, 31 (1), 59-64
    DOI 10.1111/j.1365-3083.1990.tb02743.x, PubMed 2300790
  4. Garred P, Våge DI, Mollnes TE, Harboe M (1990)
    Latex gloves as a cause of inflammation and eczema
    Lancet, 335 (8703), 1469
    DOI 10.1016/0140-6736(90)91502-2, PubMed 1972244
  5. Halstensen TS, Mollnes TE, Garred P, Fausa O, Brandtzaeg P (1990)
    Epithelial deposition of immunoglobulin G1 and activated complement (C3b and terminal complement complex) in ulcerative colitis
    Gastroenterology, 98 (5 Pt 1), 1264-71
    DOI 10.1016/0016-5085(90)90343-y, PubMed 1691118
  6. Hetland G, Garred P, Pettersen HB, Mollnes TE, Johnson E (1990)
    S protein binds to serum-treated agarose beads independently of complement activation and the formation of the terminal complement complex on the beads
    Clin Exp Immunol, 79 (3), 459-62
    DOI 10.1111/j.1365-2249.1990.tb08112.x, PubMed 1690618
  7. Mellbye OJ, Vartdal F, Pahle J, Mollnes TE (1990)
    IgG and IgA subclass distribution of total immunoglobulin and rheumatoid factors in rheumatoid tissue plasma cells
    Scand J Rheumatol, 19 (5), 333-40
    DOI 10.3109/03009749009096788, PubMed 2218430
  8. Monaco S, Bonetti B, Ferrari S, Moretto G, Nardelli E, Tedesco F, Mollnes TE, Nobile-Orazio E, Manfredini E, Bonazzi L (1990)
    Complement-mediated demyelination in patients with IgM monoclonal gammopathy and polyneuropathy
    N Engl J Med, 322 (10), 649-52
    DOI 10.1056/NEJM199003083221002, PubMed 1689461
  9. Pettersen HB, Johnson E, Garred P, Hetland G, Osen SS, Mollnes TE (1990)
    Quantification of non-activated (native) complement component C9 synthesized by alveolar macrophages from patients with sarcoidosis
    Scand J Immunol, 31 (5), 657-63
    DOI 10.1111/j.1365-3083.1990.tb02816.x, PubMed 2189215
  10. Pettersen HB, Johnson E, Mollnes TE, Garred P, Hetland G, Osen SS (1990)
    Synthesis of complement by alveolar macrophages from patients with sarcoidosis
    Scand J Immunol, 31 (1), 15-23
    DOI 10.1111/j.1365-3083.1990.tb02738.x, PubMed 1689072
  11. Roeise O, Garred P, Mollnes TE, Stadaas JO, Aasen AO (1990)
    Methylprednisolone in high doses gives different effects on the early and the late part of complement
    Eur Surg Res, 22 (1), 41-9
    DOI 10.1159/000129081, PubMed 2199200
  12. Tedesco F, Radillo O, Candussi G, Nazzaro A, Mollnes TE, Pecorari D (1990)
    Immunohistochemical detection of terminal complement complex and S protein in normal and pre-eclamptic placentae
    Clin Exp Immunol, 80 (2), 236-40
    DOI 10.1111/j.1365-2249.1990.tb05240.x, PubMed 2357851
  13. Videm V, Fosse E, Mollnes TE, Garred P, Svennevig JL (1990)
    Complement activation with bubble and membrane oxygenators in aortocoronary bypass grafting
    Ann Thorac Surg, 50 (3), 387-91
    DOI 10.1016/0003-4975(90)90480-t, PubMed 2205161
  14. Våge DI, Garred P, Lea T, Mollnes TE (1990)
    Elutable factors from latex-containing materials activate complement and inhibit cell proliferation. An in vitro biocompatibility study of medical devices
    Complement Inflamm, 7 (2), 63-70
    DOI 10.1159/000463130, PubMed 2225794

Publications 1989

  1. Brandtzaeg P, Mollnes TE, Kierulf P (1989)
    Complement activation and endotoxin levels in systemic meningococcal disease
    J Infect Dis, 160 (1), 58-65
    DOI 10.1093/infdis/160.1.58, PubMed 2471750
  2. Garred P, Mollnes TE, Kazatchkine MD (1989)
    Activation-dependent antigenic changes of human C3
    Complement Inflamm, 6 (3), 205-18
    DOI 10.1159/000463094, PubMed 2472922
  3. Garred P, Mollnes TE, Lea T, Lachmann PJ (1989)
    Enzyme immunoassay detection of circulating immune complexes by monoclonal antibodies to C3 neoepitopes with special reference to IgG concentration and to interfering anti-immunoglobulin antibodies
    J Immunol Methods, 117 (1), 59-66
    DOI 10.1016/0022-1759(89)90119-1, PubMed 2464039
  4. Garred P, Olsen J, Mollnes TE, Bilde T, Glahn BE (1989)
    Biocompatibility of urinary catheters. Effect on complement activation
    Br J Urol, 63 (4), 367-71
    DOI 10.1111/j.1464-410x.1989.tb05219.x, PubMed 2713618
  5. Halstensen TS, Mollnes TE, Brandtzaeg P (1989)
    Persistent complement activation in submucosal blood vessels of active inflammatory bowel disease: immunohistochemical evidence
    Gastroenterology, 97 (1), 10-9
    DOI 10.1016/0016-5085(89)91409-1, PubMed 2498144
  6. Halstensen TS, Mollnes TE, Fausa O, Brandtzaeg P (1989)
    Deposits of terminal complement complex (TCC) in muscularis mucosae and submucosal vessels in ulcerative colitis and Crohn's disease of the colon
    Gut, 30 (3), 361-6
    DOI 10.1136/gut.30.3.361, PubMed 2707635
  7. Hetland G, Pettersen HB, Mollnes TE, Johnson E (1989)
    S-protein is synthesized by human monocytes and macrophages in vitro
    Scand J Immunol, 29 (1), 15-21
    DOI 10.1111/j.1365-3083.1989.tb01094.x, PubMed 2466326
  8. Høgevold HE, Aasen AO, Kierulf P, Garred P, Mollnes TE, Reikerås O (1989)
    High doses of corticosteroids in total hip replacement. Effects on components of coagulation, fibrinolytic, plasma kallikrein-kinin and complement systems
    Acta Chir Scand, 155 (4-5), 247-50
    PubMed 2678856
  9. Kongsgaard UE, Smith-Erichsen N, Geiran O, Amundsen E, Mollnes TE, Garred P (1989)
    Different activation patterns in the plasma kallikrein-kinin and complement systems during coronary bypass surgery
    Acta Anaesthesiol Scand, 33 (5), 343-7
    DOI 10.1111/j.1399-6576.1989.tb02921.x, PubMed 2800971
  10. Mollnes TE (1989)
    Antigenic changes of complement components: relevance for the analysis of complement activation
    Complement Inflamm, 6 (3), 134-41
    DOI 10.1159/000463090, PubMed 2472919
  11. Mollnes TE (1989)
    [The complement system--a fascinating biological cascade. 1--physiologic aspects]
    Tidsskr Nor Laegeforen, 109 (27), 2782-8
    PubMed 2815011
  12. Mollnes TE (1989)
    [The complement system--a fascinating biological cascade. 2--clinical aspects]
    Tidsskr Nor Laegeforen, 109 (28), 2891-6
    PubMed 2815029
  13. Mollnes TE, Abrahamsen TG, Garred P (1989)
    Alterations in the terminal complement pathway in leukopenic children with malignant diseases during episodes with evidence of infection
    Complement Inflamm, 6 (6), 460-9
    DOI 10.1159/000463115, PubMed 2598645
  14. Mollnes TE, Lea T, Tschopp J (1989)
    Activation-dependent epitopes in the terminal complement pathway
    Complement Inflamm, 6 (3), 223-35
    DOI 10.1159/000463096, PubMed 2472924
  15. Roeise O, Garred P, Mollnes TE, Aasen AO (1989)
    Studies on the dose dependence of endotoxin-induced in vitro activation of the complement system
    Eur Surg Res, 21 (1), 34-41
    DOI 10.1159/000129001, PubMed 2714308
  16. Videm V, Fosse E, Mollnes TE, Ellingsen O, Pedersen T, Karlsen H (1989)
    Different oxygenators for cardiopulmonary bypass lead to varying degrees of human complement activation in vitro
    J Thorac Cardiovasc Surg, 97 (5), 764-70
    PubMed 2709867

Publications 1988

  1. Bhakdi S, Käflein R, Halstensen TS, Hugo F, Preissner KT, Mollnes TE (1988)
    Complement S-protein (vitronectin) is associated with cytolytic membrane-bound C5b-9 complexes
    Clin Exp Immunol, 74 (3), 459-64
    PubMed 2466593
  2. Brandtzaeg P, Kierulf P, Gaustad P, Dobloug J, Mollnes TE, Sirnes K (1988)
    Systemic meningococcal disease: a model infection to study acute endotoxinemia in man
    Prog Clin Biol Res, 272, 263-71
    PubMed 3393567
  3. Garred P, Mollnes TE, Lea T (1988)
    Quantification in enzyme-linked immunosorbent assay of a C3 neoepitope expressed on activated human complement factor C3
    Scand J Immunol, 27 (3), 329-35
    DOI 10.1111/j.1365-3083.1988.tb02354.x, PubMed 2451274
  4. Garred P, Mollnes TE, Lea T, Fischer E (1988)
    Characterization of a monoclonal antibody MoAb bH6 reacting with a neoepitope of human C3 expressed on C3b, iC3b, and C3c
    Scand J Immunol, 27 (3), 319-27
    DOI 10.1111/j.1365-3083.1988.tb02353.x, PubMed 2451273
  5. Halstensen TS, Mollnes TE, Brandtzaeg P (1988)
    Terminal complement complex (TCC) and S-protein (vitronectin) on follicular dendritic cells in human lymphoid tissues
    Immunology, 65 (2), 193-7
    PubMed 2461343
  6. Halstensen TS, Mollnes TE, Garred P, Brandtzaeg P (1988)
    Deposits of terminal complement complex and S-protein on follicular dendritic cells in human lymphoid tissue
    Adv Exp Med Biol, 237, 185-9
    DOI 10.1007/978-1-4684-5535-9_27, PubMed 2978199
  7. Heideman M, Norder-Hansson B, Bengtson A, Mollnes TE (1988)
    Terminal complement complexes and anaphylatoxins in septic and ischemic patients
    Arch Surg, 123 (2), 188-92
    DOI 10.1001/archsurg.1988.01400260068008, PubMed 3277584
  8. Hunziker T, Mollnes TE, Misiano G, Späth PJ (1988)
    Complement in chronic cutaneous lupus erythematosus
    Br J Dermatol, 118 (1), 131-3
    DOI 10.1111/j.1365-2133.1988.tb01762.x, PubMed 3257702
  9. Mellbye OJ, Frøland SS, Lilleaasen P, Svennevig JL, Mollnes TE (1988)
    Complement activation during cardiopulmonary bypass: comparison between the use of large volumes of plasma and dextran 70
    Eur Surg Res, 20 (2), 101-9
    DOI 10.1159/000128748, PubMed 2455645
  10. Mollnes TE, Garred P, Bergseth G (1988)
    Effect of time, temperature and anticoagulants on in vitro complement activation: consequences for collection and preservation of samples to be examined for complement activation
    Clin Exp Immunol, 73 (3), 484-8
    PubMed 2463123
  11. Mollnes TE, Klos A, Tschopp J (1988)
    Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex
    Scand J Immunol, 28 (3), 307-12
    DOI 10.1111/j.1365-3083.1988.tb01453.x, PubMed 2461581
  12. Mollnes TE, Lachmann PJ (1988)
    Regulation of complement
    Scand J Immunol, 27 (2), 127-42
    DOI 10.1111/j.1365-3083.1988.tb02331.x, PubMed 3277261
  13. Mollnes TE, Tambs KE, Myreng Y, Engebretsen LF (1988)
    Acute phase reactants and complement activation in patients with acute myocardial infarction
    Complement, 5 (1), 33-9
    DOI 10.1159/000463029, PubMed 2448082
  14. Pettersen HB, Johnson E, Mollnes TE, Garred P (1988)
    Synthesis of soluble C3 and C9 neoepitopes by human alveolar macrophages in vitro
    Scand J Immunol, 28 (4), 431-4
    DOI 10.1111/j.1365-3083.1988.tb01472.x, PubMed 2461585
  15. Sandberg G, Stenvinkel C, Mollnes TE (1988)
    Demonstration of C3d and the terminal complement complex on thymic large granular lymphocytes and common thymocytes after incubation with naturally thymocytotoxic serum
    Int Arch Allergy Appl Immunol, 87 (3), 239-46
    DOI 10.1159/000234679, PubMed 3264545
  16. Thorlacius S, Mollnes TE, Garred P, Aarli JA, Matre R, Tönder O, Halvorsen K (1988)
    Plasma exchange in myasthenia gravis: changes in serum complement and immunoglobulins
    Acta Neurol Scand, 78 (3), 221-7
    DOI 10.1111/j.1600-0404.1988.tb03650.x, PubMed 3227807
  17. Videm V, Fosse E, Mollnes TE, Garred P (1988)
    Complement activation by extracorporeal circulation: effects of precoating a membrane oxygenator circuit with human whole blood
    Scand J Thorac Cardiovasc Surg, 22 (3), 251-6
    DOI 10.3109/14017438809106071, PubMed 3227328

Publications 1987

  1. Fosse E, Mollnes TE, Ingvaldsen B (1987)
    Complement activation during major operations with or without cardiopulmonary bypass
    J Thorac Cardiovasc Surg, 93 (6), 860-6
    PubMed 3494886
  2. Fosse E, Mollnes TE, Osterud A, Aasen AO (1987)
    Effects of methylprednisolone on complement activation and leukocyte counts during cardiopulmonary bypass
    Scand J Thorac Cardiovasc Surg, 21 (3), 255-61
    DOI 10.3109/14017438709106035, PubMed 2964081
  3. Fosse E, Mollnes TE, Aasen AO, Trumpy JH, Stokke T (1987)
    Complement activation following multiple injuries
    Acta Chir Scand, 153 (5-6), 325-30
    PubMed 3499041
  4. Mollnes TE, Harboe M (1987)
    Immunohistochemical detection of the membrane and fluid-phase terminal complement complexes C5b-9(m) and SC5b-9. Consequences for interpretation and terminology
    Scand J Immunol, 26 (4), 381-6
    DOI 10.1111/j.1365-3083.1987.tb02270.x, PubMed 3685888
  5. Mollnes TE, Lachmann PJ (1987)
    Activation of the third component of complement (C3) detected by a monoclonal anti-C3'g' neoantigen antibody in a one-step enzyme immunoassay
    J Immunol Methods, 101 (2), 201-7
    DOI 10.1016/0022-1759(87)90151-7, PubMed 2440954
  6. Mollnes TE, Tschopp J (1987)
    A unique epitope exposed in native complement component C9 and hidden in the terminal SC5b-9 complex enables selective detection and quantification of non-activated C9
    J Immunol Methods, 100 (1-2), 215-21
    DOI 10.1016/0022-1759(87)90192-x, PubMed 2439601
  7. Mollnes TE, Vandvik B, Lea T, Vartdal F (1987)
    Intrathecal complement activation in neurological diseases evaluated by analysis of the terminal complement complex
    J Neurol Sci, 78 (1), 17-28
    DOI 10.1016/0022-510x(87)90074-8, PubMed 3572448

Publications 1986

  1. Mollnes TE, Lea T, Mellbye OJ, Pahle J, Grand O, Harboe M (1986)
    Complement activation in rheumatoid arthritis evaluated by C3dg and the terminal complement complex
    Arthritis Rheum, 29 (6), 715-21
    DOI 10.1002/art.1780290603, PubMed 3718564
  2. Mollnes TE, Lea T, Rogde S, Tedesco F (1986)
    The terminal complement complex in sera deficient in the eighth component of complement (C8)
    Scand J Immunol, 24 (3), 307-12
    DOI 10.1111/j.1365-3083.1986.tb02098.x, PubMed 3749815
  3. Mollnes TE, Ng YC, Peters DK, Lea T, Tschopp J, Harboe M (1986)
    Effect of nephritic factor on C3 and on the terminal pathway of complement in vivo and in vitro
    Clin Exp Immunol, 65 (1), 73-9
    PubMed 3641694
  4. Mollnes TE, Paus A (1986)
    Complement activation in synovial fluid and tissue from patients with juvenile rheumatoid arthritis
    Arthritis Rheum, 29 (11), 1359-64
    DOI 10.1002/art.1780291108, PubMed 3778542
  5. Tschopp J, Mollnes TE (1986)
    Antigenic crossreactivity of the alpha subunit of complement component C8 with the cysteine-rich domain shared by complement component C9 and low density lipoprotein receptor
    Proc Natl Acad Sci U S A, 83 (12), 4223-7
    DOI 10.1073/pnas.83.12.4223, PubMed 2424021

Publications 1985

  1. Mollnes TE (1985)
    Early- and late-phase activation of complement evaluated by plasma levels of C3d,g and the terminal complement complex
    Complement, 2 (2-3), 156-64
    DOI 10.1159/000467856, PubMed 3878764
  2. Mollnes TE (1985)
    Quantification of the C3d split products of human complement by a sensitive enzyme-linked immunosorbent assay
    Scand J Immunol, 21 (6), 607-13
    DOI 10.1111/j.1365-3083.1985.tb01851.x, PubMed 3895396
  3. Mollnes TE, Frøland SS, Harboe M (1985)
    Increased plasma levels of the terminal complement complex in patients with evidence of complement activation
    Complement, 2 (2-3), 175-84
    DOI 10.1159/000467858, PubMed 3878765
  4. Mollnes TE, Lea T, Frøland SS, Harboe M (1985)
    Quantification of the terminal complement complex in human plasma by an enzyme-linked immunosorbent assay based on monoclonal antibodies against a neoantigen of the complex
    Scand J Immunol, 22 (2), 197-202
    DOI 10.1111/j.1365-3083.1985.tb01871.x, PubMed 2412280
  5. Mollnes TE, Lea T, Harboe M, Tschopp J (1985)
    Monoclonal antibodies recognizing a neoantigen of poly(C9) detect the human terminal complement complex in tissue and plasma
    Scand J Immunol, 22 (2), 183-95
    DOI 10.1111/j.1365-3083.1985.tb01870.x, PubMed 4035298

Publications 1984

  1. Mollnes TE, Lea T, Harboe M (1984)
    Detection and quantification of the terminal C5b-9 complex of human complement by a sensitive enzyme-linked immunosorbent assay
    Scand J Immunol, 20 (2), 157-66
    DOI 10.1111/j.1365-3083.1984.tb00989.x, PubMed 6474098