Publications by Tom Eirik Mollnes

469 publications found

Publications 2018

  1. Askarian F, Lapek JD, Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M (2018)
    [No title available]
    Front Microbiol, 9, 262
    PubMed 29515544
  2. Langeland H, Bergum D, Løberg M, Bjørnstad K, Damås JK, Mollnes TE, Skjærvold NK, Klepstad P (2018)
    Transitions Between Circulatory States After Out-of-Hospital Cardiac Arrest: Protocol for an Observational, Prospective Cohort Study
    JMIR Res Protoc, 7 (1), e17
    PubMed 29351897
  3. Orrem HL, Nilsson PH, Pischke SE, Grindheim G, Garred P, Seljeflot I, Husebye T, Aukrust P, Yndestad A, Andersen GØ, Barratt-Due A, Mollnes TE (2018)
    Acute heart failure following myocardial infarction: complement activation correlates with the severity of heart failure in patients developing cardiogenic shock
    ESC Heart Fail (in press)
    PubMed 29424484
  4. Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Skattum L, Bosnes V, Garred P, Frøland SS, Mollnes TE, Aukrust P, Heggelund L (2018)
    Low Levels of Immunoglobulins and Mannose-Binding Lectin Are Not Associated With Etiology, Severity, or Outcome in Community-Acquired Pneumonia
    Open Forum Infect Dis, 5 (2), ofy002
    PubMed 29410975
  5. Skjeflo EW, Christiansen D, Fure H, Ludviksen JK, Woodruff TM, Espevik T, Nielsen EW, Brekke OL, Mollnes TE (2018)
    Staphylococcus aureus-induced Complement Activation Promotes Tissue Factor-mediated Coagulation
    J Thromb Haemost (in press)
    PubMed 29437288
  6. Thomas AM, Schjalm C, Nilsson PH, Lindenskov PHH, Rørtveit R, Solberg R, Saugstad OD, Berglund MM, Strömberg P, Lau C, Espevik T, Jansen JH, Castellheim A, Mollnes TE, Barratt-Due A (2018)
    Combined Inhibition of C5 and CD14 Attenuates Systemic Inflammation in a Piglet Model of Meconium Aspiration Syndrome
    Neonatology, 113 (4), 322-330 (in press)
    PubMed 29486477

Publications 2017

  1. Bakke SS, Aune MH, Niyonzima N, Pilely K, Ryan L, Skjelland M, Garred P, Aukrust P, Halvorsen B, Latz E, Damås JK, Mollnes TE, Espevik T (2017)
    Cyclodextrin Reduces Cholesterol Crystal-Induced Inflammation by Modulating Complement Activation
    J Immunol, 199 (8), 2910-2920
    PubMed 28855312
  2. Fiane KKH, Dahle G, Bendz B, Halvorsen PS, Abdelnoor M, Mollnes TE, Fosse E (2017)
    Reduced inflammatory response by transcatheter, as compared to surgical aortic valve replacement
    Scand Cardiovasc J, 52 (1), 43-50
    PubMed 29233022
  3. Gravastrand C, Hamad S, Fure H, Steinkjer B, Ryan L, Oberholzer J, Lambris JD, Lacík I, Mollnes TE, Espevik T, Brekke OL, Rokstad AM (2017)
    Alginate microbeads are coagulation compatible, while alginate microcapsules activate coagulation secondary to complement or directly through FXII
    Acta Biomater, 58, 158-167
    PubMed 28576714
  4. Gustavsen A, Skattum L, Bergseth G, Lorentzen B, Floisand Y, Bosnes V, Mollnes TE, Barratt-Due A (2017)
    Effect on mother and child of eculizumab given before caesarean section in a patient with severe antiphospholipid syndrome: A case report
    Medicine (Baltimore), 96 (11), e6338
    PubMed 28296762
  5. Harboe M, Johnson C, Nymo S, Ekholt K, Schjalm C, Lindstad JK, Pharo A, Hellerud BC, Nilsson Ekdahl K, Mollnes TE, Nilsson PH (2017)
    Properdin binding to complement activating surfaces depends on initial C3b deposition
    Proc Natl Acad Sci U S A, 114 (4), E534-E539
    PubMed 28069958
  6. Hellerud BC, Orrem HL, Dybwik K, Pischke SE, Baratt-Due A, Castellheim A, Fure H, Bergseth G, Christiansen D, Nunn MA, Espevik T, Lau C, Brandtzæg P, Nielsen EW, Mollnes TE (2017)
    Combined inhibition of C5 and CD14 efficiently attenuated the inflammatory response in a porcine model of meningococcal sepsis
    J Intensive Care, 5, 21
    PubMed 28261486
  7. Hennø LT, Storjord E, Christiansen D, Bergseth G, Ludviksen JK, Fure H, Barene S, Nielsen EW, Mollnes TE, Brekke OL (2017)
    Effect of the anticoagulant, storage time and temperature of blood samples on the concentrations of 27 multiplex assayed cytokines - Consequences for defining reference values in healthy humans
    Cytokine, 97, 86-95
    PubMed 28595117
  8. Keshari RS, Silasi R, Popescu NI, Patel MM, Chaaban H, Lupu C, Coggeshall KM, Mollnes TE, DeMarco SJ, Lupu F (2017)
    Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of<i>Escherichia coli</i>sepsis
    Proc Natl Acad Sci U S A, 114 (31), E6390-E6399
    PubMed 28720697
  9. Nilsson PH, Thomas AM, Bergseth G, Gustavsen A, Volokhina EB, van den Heuvel LP, Barratt-Due A, Mollnes TE (2017)
    Eculizumab-C5 complexes express a C5a neoepitope in vivo: Consequences for interpretation of patient complement analyses
    Mol Immunol, 89, 111-114
    PubMed 28610663
  10. Paunas TIF, Finne K, Leh S, Marti HP, Mollnes TE, Berven F, Vikse BE (2017)
    Glomerular abundance of complement proteins characterized by proteomic analysis of laser-captured microdissected glomeruli associates with progressive disease in IgA nephropathy
    Clin Proteomics, 14, 30
    PubMed 28814945
  11. Pischke SE, Gustavsen A, Orrem HL, Egge KH, Courivaud F, Fontenelle H, Despont A, Bongoni AK, Rieben R, Tønnessen TI, Nunn MA, Scott H, Skulstad H, Barratt-Due A, Mollnes TE (2017)
    Complement factor 5 blockade reduces porcine myocardial infarction size and improves immediate cardiac function
    Basic Res Cardiol, 112 (3), 20
    PubMed 28258298
  12. Ricklin D, Barratt-Due A, Mollnes TE (2017)
    Complement in clinical medicine: Clinical trials, case reports and therapy monitoring
    Mol Immunol, 89, 10-21
    PubMed 28576323
  13. Shahini N, Michelsen AE, Nilsson PH, Ekholt K, Gullestad L, Broch K, Dahl CP, Aukrust P, Ueland T, Mollnes TE, Yndestad A, Louwe MC (2017)
    The alternative complement pathway is dysregulated in patients with chronic heart failure
    Sci Rep, 7, 42532
    PubMed 28195242
  14. Shields KJ, Mollnes TE, Eidet JR, Mikkelsen K, Almdahl SM, Bottazzi B, Lyberg T, Manzi S, Ahearn JM, Hollan I (2017)
    Plasma complement and vascular complement deposition in patients with coronary artery disease with and without inflammatory rheumatic diseases
    PLoS One, 12 (3), e0174577
    PubMed 28362874
  15. Siljan WW, Holter JC, Nymo SH, Husebye E, Ueland T, Aukrust P, Mollnes TE, Heggelund L (2017)
    Cytokine responses, microbial aetiology and short-term outcome in community-acquired pneumonia
    Eur J Clin Invest, 48 (1)
    PubMed 29171871
  16. Wibroe PP, Anselmo AC, Nilsson PH, Sarode A, Gupta V, Urbanics R, Szebeni J, Hunter AC, Mitragotri S, Mollnes TE, Moghimi SM (2017)
    Bypassing adverse injection reactions to nanoparticles through shape modification and attachment to erythrocytes
    Nat Nanotechnol, 12 (6), 589-594
    PubMed 28396605
  17. Wolf-Grosse S, Rokstad AM, Ali S, Lambris JD, Mollnes TE, Nilsen AM, Stenvik J (2017)
    Iron oxide nanoparticles induce cytokine secretion in a complement-dependent manner in a human whole blood model
    Int J Nanomedicine, 12, 3927-3940
    PubMed 28579778
  18. Wyller VB, Nguyen CB, Ludviksen JA, Mollnes TE (2017)
    Transforming growth factor beta (TGF-β) in adolescent chronic fatigue syndrome
    J Transl Med, 15 (1), 245
    PubMed 29202780

Publications 2016

  1. Aresvik DM, Lima K, Øverland T, Mollnes TE, Abrahamsen TG (2016)
    Increased Levels of Interferon-Inducible Protein 10 (IP-10) in 22q11.2 Deletion Syndrome
    Scand J Immunol, 83 (3), 188-94
    PubMed 26708691
  2. Barratt-Due A, Floisand Y, Orrem HL, Kvam AK, Holme PA, Bergseth G, Tjonnfjore GE, Mollnes TE (2016)
    Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome
    RHEUMATOLOGY, 55 (7), 1337-1340
  3. Barratt-Due A, Fløisand Y, Orrem HL, Kvam AK, Holme PA, Bergseth G, Tjønnfjord GE, Mollnes TE (2016)
    Complement activation is a crucial pathogenic factor in catastrophic antiphospholipid syndrome
    Rheumatology (Oxford), 55 (7), 1337-9
    PubMed 27105662
  4. Barratt-Due A, Pischke SE, Nilsson PH, Espevik T, Mollnes TE (2016)
    Dual inhibition of complement and Toll-like receptors as a novel approach to treat inflammatory diseases-C3 or C5 emerge together with CD14 as promising targets
    J Leukoc Biol, 101 (1), 193-204
    PubMed 27581539
  5. Eide IA, Åsberg A, Svensson M, Ueland T, Mollnes TE, Hartmann A, Bjerve KS, Michelsen A, Aukrust P, Christensen JH, Schmidt EB, Jenssen T (2016)
    Plasma Levels of Marine n-3 Fatty Acids Are Inversely Correlated With Proinflammatory Markers sTNFR1 and IL-6 in Renal Transplant Recipients
    J Ren Nutr, 27 (3), 161-168
    PubMed 27838193
  6. Garabet L, Gilboe IM, Mowinckel MC, Jacobsen AF, Mollnes TE, Sandset PM, Jacobsen EM (2016)
    Antiphospholipid Antibodies are Associated with Low Levels of Complement C3 and C4 in Patients with Systemic Lupus Erythematosus
    Scand J Immunol, 84 (2), 95-9
    PubMed 27135178
  7. Gustavsen A, Nymo S, Landsem A, Christiansen D, Ryan L, Husebye H, Lau C, Pischke SE, Lambris JD, Espevik T, Mollnes TE (2016)
    Combined Inhibition of Complement and CD14 Attenuates Bacteria-Induced Inflammation in Human Whole Blood More Efficiently Than Antagonizing the Toll-like Receptor 4-MD2 Complex
    J Infect Dis, 214 (1), 140-50
    PubMed 26977050
  8. Hestad KA, Engedal K, Whist JE, Aukrust P, Farup PG, Mollnes TE, Ueland T (2016)
    Patients with depression display cytokine levels in serum and cerebrospinal fluid similar to patients with diffuse neurological symptoms without a defined diagnosis
    Neuropsychiatr Dis Treat, 12, 817-22
    PubMed 27110115
  9. Jørgensen SF, Trøseid M, Kummen M, Anmarkrud JA, Michelsen AE, Osnes LT, Holm K, Høivik ML, Rashidi A, Dahl CP, Vesterhus M, Halvorsen B, Mollnes TE, Berge RK, Moum B, Lundin KE, Fevang B, Ueland T, Karlsen TH, Aukrust P, Hov JR (2016)
    Altered gut microbiota profile in common variable immunodeficiency associates with levels of lipopolysaccharide and markers of systemic immune activation
    Mucosal Immunol, 9 (6), 1455-1465
    PubMed 26982597
  10. Landsem A, Fure H, Mollnes TE, Nielsen EW, Brekke OL (2016)
    C1-inhibitor efficiently delays clot development in normal human whole blood and inhibits Escherichia coli-induced coagulation measured by thromboelastometry
    Thromb Res, 143, 63-70
    PubMed 27197075
  11. Lappegård KT, Enebakk T, Thunhaug H, Ludviksen JK, Mollnes TE, Hovland A (2016)
    LDL apheresis activates the complement system and the cytokine network, whereas PCSK9 inhibition with evolocumab induces no inflammatory response
    J Clin Lipidol, 10 (6), 1481-1487
    PubMed 27919366
  12. Niyonzima N, Halvorsen B, Sporsheim B, Garred P, Aukrust P, Mollnes TE, Espevik T (2016)
    Complement activation by cholesterol crystals triggers a subsequent cytokine response
    Mol Immunol, 84, 43-50
    PubMed 27692470
  13. Nymo S, Gustavsen A, Nilsson PH, Lau C, Espevik T, Mollnes TE (2016)
    Human Endothelial Cell Activation by Escherichia coli and Staphylococcus aureus Is Mediated by TNF and IL-1β Secondarily to Activation of C5 and CD14 in Whole Blood
    J Immunol, 196 (5), 2293-9
    PubMed 26800874
  14. Otterdal K, Portillo A, Astrup E, Ludviksen J, Davì G, Holm S, Santilli F, Vitale G, Raoult D, Olano JP, Schjalm C, Halvorsen B, Oteo JA, Mollnes TE, Aukrust P, Nilsson PH (2016)
    High serum CXCL10 in Rickettsia conorii infection is endothelial cell mediated subsequent to whole blood activation
    Cytokine, 83, 269-274
    PubMed 27180202
  15. Otterdal K, Portillo A, Astrup E, Ludviksen JK, Schjalm C, Raoult D, Olano JP, Halvorsen B, Oteo JA, Aukrust P, Mollnes TE, Nilsson PH (2016)
    Rickettsia conorii is a potent complement activator in vivo and combined inhibition of complement and CD14 is required for attenuation of the cytokine response ex vivo
    Clin Microbiol Infect, 22 (8), 734.e1-6
    PubMed 27217049
  16. Pilely K, Rosbjerg A, Genster N, Gal P, Pál G, Halvorsen B, Holm S, Aukrust P, Bakke SS, Sporsheim B, Nervik I, Niyonzima N, Bartels ED, Stahl GL, Mollnes TE, Espevik T, Garred P (2016)
    Cholesterol Crystals Activate the Lectin Complement Pathway via Ficolin-2 and Mannose-Binding Lectin: Implications for the Progression of Atherosclerosis
    J Immunol, 196 (12), 5064-74
    PubMed 27183610
  17. Siljan WW, Holter JC, Nymo SH, Schjalm C, Müller F, Jenum PA, Husebye E, Ueland T, Aukrust P, Mollnes TE, Heggelund L (2016)
    Circulating cell-free DNA is elevated in community-acquired bacterial pneumonia and predicts short-term outcome
    J Infect, 73 (4), 383-6
    PubMed 27452197
  18. Smedbråten J, Mjøen G, Hartmann A, Åsberg A, Rollag H, Mollnes TE, Sandvik L, Fagerland MW, Thiel S, Sagedal S (2016)
    Low level of MAp44, an inhibitor of the lectin complement pathway, and long-term graft and patient survival; a cohort study of 382 kidney recipients
    BMC Nephrol, 17 (1), 148
    PubMed 27760523
  19. Smedbråten J, Sagedal S, Åsberg A, Hartmann A, Rollag H, Mjøen G, Fagerland MW, Hansen SW, Mollnes TE, Thiel S (2016)
    Collectin Liver 1 and Collectin Kidney 1 of the Lectin Complement Pathway Are Associated With Mortality After Kidney Transplantation
    Am J Transplant, 17 (1), 265-271
    PubMed 27341702
  20. Stiksrud B, Lorvik KB, Kvale D, Mollnes TE, Ueland PM, Trøseid M, Taskén K, Dyrhol-Riise AM (2016)
    Plasma IP-10 Is Increased in Immunological NonResponders and Associated With Activated Regulatory T Cells and Persisting Low CD4 Counts
    J Acquir Immune Defic Syndr, 73 (2), 138-48
    PubMed 27632144
  21. Storjord E, Dahl JA, Landsem A, Fure H, Ludviksen JK, Goldbeck-Wood S, Karlsen BO, Berg KS, Mollnes TE, W Nielsen E, Brekke OL (2016)
    Systemic inflammation in acute intermittent porphyria: a case-control study
    Clin Exp Immunol, 187 (3), 466-479
    PubMed 27859020
  22. Stylianou E, Ueland T, Borchsenius F, Michelsen AE, Øvstebø R, Mollnes TE, Skjønsberg OH, Aukrust P (2016)
    Specific allergen immunotherapy: effect on IgE, IgG4 and chemokines in patients with allergic rhinitis
    Scand J Clin Lab Invest, 76 (2), 118-27
    PubMed 26878875
  23. Ørning P, Hoem KS, Coron AE, Skjåk-Bræk G, Mollnes TE, Brekke OL, Espevik T, Rokstad AM (2016)
    Alginate microsphere compositions dictate different mechanisms of complement activation with consequences for cytokine release and leukocyte activation
    J Control Release, 229, 58-69
    PubMed 26993426

Publications 2015

  1. Asprusten TT, Fagermoen E, Sulheim D, Skovlund E, Sørensen Ø, Mollnes TE, Wyller VB (2015)
    Study findings challenge the content validity of the Canadian Consensus Criteria for adolescent chronic fatigue syndrome
    Acta Paediatr, 104 (5), 498-503
    PubMed 25640602
  2. Berg A, Otterdal K, Patel S, Gonca M, David C, Dalen I, Nymo S, Nilsson M, Nordling S, Magnusson PU, Ueland T, Prato M, Giribaldi G, Mollnes TE, Aukrust P, Langeland N, Nilsson PH (2015)
    Complement Activation Correlates With Disease Severity and Contributes to Cytokine Responses in Plasmodium falciparum Malaria
    J Infect Dis, 212 (11), 1835-40
    PubMed 25980034
  3. Bergstrøm B, Aune MH, Awuh JA, Kojen JF, Blix KJ, Ryan L, Flo TH, Mollnes TE, Espevik T, Stenvik J (2015)
    TLR8 Senses Staphylococcus aureus RNA in Human Primary Monocytes and Macrophages and Induces IFN-β Production via a TAK1-IKKβ-IRF5 Signaling Pathway
    J Immunol, 195 (3), 1100-11
    PubMed 26085680
  4. Blom AM, Österborg A, Mollnes TE, Okroj M (2015)
    Antibodies reactive to cleaved sites in complement proteins enable highly specific measurement of soluble markers of complement activation
    Mol Immunol, 66 (2), 164-70
    PubMed 25795308
  5. Egge KH, Barratt-Due A, Nymo S, Lindstad JK, Pharo A, Lau C, Espevik T, Thorgersen EB, Mollnes TE (2015)
    The anti-inflammatory effect of combined complement and CD14 inhibition is preserved during escalating bacterial load
    Clin Exp Immunol, 181 (3), 457-67
    PubMed 25907631
  6. Egge KH, Thorgersen EB, Pischke SE, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn MA, Barratt-Due A, Mollnes TE (2015)
    Organ inflammation in porcine Escherichia coli sepsis is markedly attenuated by combined inhibition of C5 and CD14
    Immunobiology, 220 (8), 999-1005
    PubMed 25956456
  7. Fretland AA, Sokolov A, Postriganova N, Kazaryan AM, Pischke SE, Nilsson PH, Rognes IN, Bjornbeth BA, Fagerland MW, Mollnes TE, Edwin B (2015)
    Inflammatory Response After Laparoscopic Versus Open Resection of Colorectal Liver Metastases: Data From the Oslo-CoMet Trial
    Medicine (Baltimore), 94 (42), e1786
    PubMed 26496309
  8. Hein E, Munthe-Fog L, Thiara AS, Fiane AE, Mollnes TE, Garred P (2015)
    Heparin-coated cardiopulmonary bypass circuits selectively deplete the pattern recognition molecule ficolin-2 of the lectin complement pathway in vivo
    Clin Exp Immunol, 179 (2), 294-9
    PubMed 25174443
  9. Hellerud BC, Olstad OK, Nielsen EW, Trøseid AM, Skadberg Ø, Thorgersen EB, Vege Å, Mollnes TE, Brandtzæg P (2015)
    Massive Organ Inflammation in Experimental and in Clinical Meningococcal Septic Shock
    Shock, 44 (5), 458-69
    PubMed 26473439
  10. Hovland A, Jonasson L, Garred P, Yndestad A, Aukrust P, Lappegård KT, Espevik T, Mollnes TE (2015)
    The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis
    Atherosclerosis, 241 (2), 480-94
    PubMed 26086357
  11. Huang S, Engberg AE, Jonsson N, Sandholm K, Nicholls IA, Mollnes TE, Fromell K, Nilsson B, Ekdahl KN (2015)
    Reciprocal relationship between contact and complement system activation on artificial polymers exposed to whole human blood
    Biomaterials, 77, 111-9
    PubMed 26584351
  12. Khan F, Pharo A, Lindstad JK, Mollnes TE, Tønnessen TI, Pischke SE (2015)
    Effect of Perfusion Fluids on Recovery of Inflammatory Mediators in Microdialysis
    Scand J Immunol, 82 (5), 467-75
    PubMed 26099791
  13. Landsem A, Fure H, Christiansen D, Nielsen EW, Østerud B, Mollnes TE, Brekke OL (2015)
    The key roles of complement and tissue factor in Escherichia coli-induced coagulation in human whole blood
    Clin Exp Immunol, 182 (1), 81-9
    PubMed 26241501
  14. Lappegård KT, Bjerre A, Tjønnfjord GE, Mollnes TE (2015)
    Therapeutic complement inhibition – from experimental to clinical medicine
    Tidsskr Nor Laegeforen, 135 (19), 1745-9
    PubMed 26486669
  15. Lappegård KT, Bjørnstad H, Mollnes TE, Hovland A (2015)
    Effect of Cardiac Resynchronization Therapy on Inflammation in Congestive Heart Failure: A Review
    Scand J Immunol, 82 (3), 191-8
    PubMed 26099323
  16. Lau C, Nygård S, Fure H, Olstad OK, Holden M, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    CD14 and complement crosstalk and largely mediate the transcriptional response to Escherichia coli in human whole blood as revealed by DNA microarray
    PLoS One, 10 (2), e0117261
    PubMed 25706641
  17. Lau C, Olstad OK, Holden M, Nygård S, Fure H, Lappegård KT, Brekke OL, Espevik T, Hovig E, Mollnes TE (2015)
    Gene expression profiling of Gram-negative bacteria-induced inflammation in human whole blood: The role of complement and CD14-mediated innate immune response
    Genom Data, 5, 176-83
    PubMed 26484252
  18. Lindenskov PH, Castellheim A, Saugstad OD, Mollnes TE (2015)
    Meconium aspiration syndrome: possible pathophysiological mechanisms and future potential therapies
    Neonatology, 107 (3), 225-30
    PubMed 25721501
  19. Meroni PL, Macor P, Durigutto P, De Maso L, Gerosa M, Ferraresso M, Borghi MO, Mollnes TE, Tedesco F (2015)
    Complement activation in antiphospholipid syndrome and its inhibition to prevent rethrombosis after arterial surgery
    Blood, 127 (3), 365-7
    PubMed 26644452
  20. Neupane SP, Lien L, Ueland T, Mollnes TE, Aukrust P, Bramness JG (2015)
    Serum brain-derived neurotrophic factor levels in relation to comorbid depression and cytokine levels in Nepalese men with alcohol-use disorders
    Alcohol, 49 (5), 471-8
    PubMed 25873205
  21. Nilsson B, Ekdahl KN, Kemper C, Mollnes TE (2015)
    Preface. 15th European Meeting on Complement in Human Disease 2015, Uppsala, Sweden
    Mol Immunol, 67 (1), 1-2
    PubMed 25934434
  22. Niyonzima N, Samstad EO, Aune MH, Ryan L, Bakke SS, Rokstad AM, Wright SD, Damås JK, Mollnes TE, Latz E, Espevik T (2015)
    Reconstituted High-Density Lipoprotein Attenuates Cholesterol Crystal-Induced Inflammatory Responses by Reducing Complement Activation
    J Immunol, 195 (1), 257-64
    PubMed 26026058
  23. Prebensen C, Ueland T, Michelsen AE, Lind A, Pettersen FO, Mollnes TE, Aukrust P, Dyrhol-Riise AM, Kvale D (2015)
    High MIP-1β Levels in Plasma Predict Long-Term Immunological Nonresponse to Suppressive Antiretroviral Therapy in HIV Infection
    J Acquir Immune Defic Syndr, 69 (4), 395-402
    PubMed 26115437
  24. Skjeflo EW, Sagatun C, Dybwik K, Aam S, Urving SH, Nunn MA, Fure H, Lau C, Brekke OL, Huber-Lang M, Espevik T, Barratt-Due A, Nielsen EW, Mollnes TE (2015)
    Combined inhibition of complement and CD14 improved outcome in porcine polymicrobial sepsis
    Crit Care, 19, 415
    PubMed 26612199
  25. Smedbråten YV, Sagedal S, Mjøen G, Hartmann A, Fagerland MW, Rollag H, Mollnes TE, Thiel S (2015)
    High ficolin-3 level at the time of transplantation is an independent risk factor for graft loss in kidney transplant recipients
    Transplantation, 99 (4), 791-6
    PubMed 25222012
  26. Volokhina EB, Bergseth G, van de Kar NC, van den Heuvel LP, Mollnes TE (2015)
    Eculizumab treatment efficiently prevents C5 cleavage without C5a generation in vivo
    Blood, 126 (2), 278-9
    PubMed 26160188
  27. Volokhina EB, van de Kar NC, Bergseth G, van der Velden TJ, Westra D, Wetzels JF, van den Heuvel LP, Mollnes TE (2015)
    Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome
    Clin Immunol, 160 (2), 237-43
    PubMed 26111482
  28. Volokhina EB, Westra D, van der Velden TJ, van de Kar NC, Mollnes TE, van den Heuvel LP (2015)
    Complement activation patterns in atypical haemolytic uraemic syndrome during acute phase and in remission
    Clin Exp Immunol, 181 (2), 306-13
    PubMed 25079699
  29. Wergeland I, Pullar N, Assmus J, Ueland T, Tonby K, Feruglio S, Kvale D, Damås JK, Aukrust P, Mollnes TE, Dyrhol-Riise AM (2015)
    IP-10 differentiates between active and latent tuberculosis irrespective of HIV status and declines during therapy
    J Infect, 70 (4), 381-91
    PubMed 25597826
  30. Wyller VB, Reme SE, Mollnes TE (2015)
    Chronic fatigue syndrome/myalgic encephalo-myelitis--pathophysiology, diagnosis and treatment
    Tidsskr Nor Laegeforen, 135 (23-24), 2172-5
    PubMed 26674040
  31. Würzner R, Tedesco F, Garred P, Mollnes TE, Truedsson L, Turner MW, Sommarin Y, Wieslander J, Sim RB (2015)
    European Union funded project on the development of a whole complement deficiency screening ELISA-A story of success and an exceptional manager: Mohamed R. Daha
    Mol Immunol, 68 (1), 63-6
    PubMed 26006049

Publications 2014

  1. Berg A, Patel S, Gonca M, David C, Otterdal K, Ueland T, Dalen I, Kvaløy JT, Mollnes TE, Aukrust P, Langeland N (2014)
    Cytokine network in adults with falciparum Malaria and HIV-1: increased IL-8 and IP-10 levels are associated with disease severity
    PLoS One, 9 (12), e114480
    PubMed 25503583
  2. Bergseth G, Ludviksen JK, Kirschfink M, Giclas PC, Nilsson B, Mollnes TE (2014)
    An international serum standard for application in assays to detect human complement activation products (vol 56, pg 232, 2013)
    Mol. Immunol., 60 (2), 115
  3. Bisschops LL, van der Hoeven JG, Mollnes TE, Hoedemaekers CW (2014)
    Seventy-two hours of mild hypothermia after cardiac arrest is associated with a lowered inflammatory response during rewarming in a prospective observational study
    Crit Care, 18 (5), 546
    PubMed 25304549
  4. Blom AM, Volokhina EB, Fransson V, Strömberg P, Berghard L, Viktorelius M, Mollnes TE, López-Trascasa M, van den Heuvel LP, Goodship TH, Marchbank KJ, Okroj M (2014)
    A novel method for direct measurement of complement convertases activity in human serum
    Clin Exp Immunol, 178 (1), 142-53
    PubMed 24853370
  5. Engberg AE, Nilsson PH, Huang S, Fromell K, Hamad OA, Mollnes TE, Rosengren-Holmberg JP, Sandholm K, Teramura Y, Nicholls IA, Nilsson B, Ekdahl KN (2014)
    Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma
    Biomaterials, 36, 55-65
    PubMed 25292422
  6. Hallstensen RF, Bergseth G, Foss S, Jæger S, Gedde-Dahl T, Holt J, Christiansen D, Lau C, Brekke OL, Armstrong E, Stefanovic V, Andersen JT, Sandlie I, Mollnes TE (2014)
    Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn
    Immunobiology, 220 (4), 452-9
    PubMed 25468724
  7. Huber-Lang M, Barratt-Due A, Pischke SE, Sandanger Ø, Nilsson PH, Nunn MA, Denk S, Gaus W, Espevik T, Mollnes TE (2014)
    Double blockade of CD14 and complement C5 abolishes the cytokine storm and improves morbidity and survival in polymicrobial sepsis in mice
    J Immunol, 192 (11), 5324-31
    PubMed 24790148
  8. Lappegård KT, Garred P, Jonasson L, Espevik T, Aukrust P, Yndestad A, Mollnes TE, Hovland A (2014)
    A vital role for complement in heart disease
    Mol Immunol, 61 (2), 126-34
    PubMed 25037633
  9. Lind A, Brekke K, Pettersen FO, Mollnes TE, Trøseid M, Kvale D (2014)
    A parameter for IL-10 and TGF-ß mediated regulation of HIV-1 specific T cell activation provides novel information and relates to progression markers
    PLoS One, 9 (1), e85604
    PubMed 24416431
  10. Neupane SP, Lien L, Martinez P, Aukrust P, Ueland T, Mollnes TE, Hestad K, Bramness JG (2014)
    High frequency and intensity of drinking may attenuate increased inflammatory cytokine levels of major depression in alcohol-use disorders
    CNS Neurosci Ther, 20 (10), 898-904
    PubMed 24995667
  11. Nymo S, Niyonzima N, Espevik T, Mollnes TE (2014)
    Cholesterol crystal-induced endothelial cell activation is complement-dependent and mediated by TNF
    Immunobiology, 219 (10), 786-92
    PubMed 25053140
  12. Ostvik AE, Granlund Av, Gustafsson BI, Torp SH, Espevik T, Mollnes TE, Damås JK, Sandvik AK (2014)
    Mucosal toll-like receptor 3-dependent synthesis of complement factor B and systemic complement activation in inflammatory bowel disease
    Inflamm Bowel Dis, 20 (6), 995-1003
    PubMed 24739633
  13. Owen EP, Würzner R, Leisegang F, Rizkallah P, Whitelaw A, Simpson J, Thomas AD, Harris CL, Giles JL, Hellerud BC, Mollnes TE, Morgan BP, Potter PC, Orren A (2014)
    A complement C5 gene mutation, c.754G>A:p.A252T, is common in the Western Cape, South Africa and found to be homozygous in seven percent of Black African meningococcal disease cases
    Mol Immunol, 64 (1), 170-6
    PubMed 25534848
  14. Samstad EO, Niyonzima N, Nymo S, Aune MH, Ryan L, Bakke SS, Lappegård KT, Brekke OL, Lambris JD, Damås JK, Latz E, Mollnes TE, Espevik T (2014)
    Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release
    J Immunol, 192 (6), 2837-45
    PubMed 24554772
  15. Skjeflo EW, Christiansen D, Espevik T, Nielsen EW, Mollnes TE (2014)
    Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model
    J Immunol, 192 (6), 2857-64
    PubMed 24516199
  16. Wyller VB, Sørensen Ø, Sulheim D, Fagermoen E, Ueland T, Mollnes TE (2014)
    Plasma cytokine expression in adolescent chronic fatigue syndrome
    Brain Behav Immun, 46, 80-6
    PubMed 25555530

Publications 2013

  1. Auråen H, Mollnes TE, Bjørtuft Ø, Bakkan PA, Geiran O, Kongerud J, Fiane A, Holm AM (2013)
    Multiorgan procurement increases systemic inflammation in brain dead donors
    Clin Transplant, 27 (4), 613-8
    PubMed 23803161
  2. Barratt-Due A, Thorgersen EB, Egge K, Pischke S, Sokolov A, Hellerud BC, Lindstad JK, Pharo A, Bongoni AK, Rieben R, Nunn M, Scott H, Mollnes TE (2013)
    Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis
    J Immunol, 191 (2), 819-27
    PubMed 23761634
  3. Bergseth G, Ludviksen JK, Kirschfink M, Giclas PC, Nilsson B, Mollnes TE (2013)
    An international serum standard for application in assays to detect human complement activation products
    Mol Immunol, 56 (3), 232-9
    PubMed 23787367
  4. Brekke OL, Waage C, Christiansen D, Fure H, Qu H, Lambris JD, Østerud B, Nielsen EW, Mollnes TE (2013)
    The effects of selective complement and CD14 inhibition on the E. coli-induced tissue factor mRNA upregulation, monocyte tissue factor expression, and tissue factor functional activity in human whole blood
    Adv Exp Med Biol, 735, 123-36
    PubMed 23402023
  5. Egge KH, Thorgersen EB, Lindstad JK, Pharo A, Lambris JD, Barratt-Due A, Mollnes TE (2013)
    Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood
    Innate Immun, 20 (1), 68-77
    PubMed 23669326
  6. Ehrnthaller C, Huber-Lang M, Nilsson P, Bindl R, Redeker S, Recknagel S, Rapp A, Mollnes T, Amling M, Gebhard F, Ignatius A (2013)
    Complement C3 and C5 deficiency affects fracture healing
    PLoS One, 8 (11), e81341
    PubMed 24260573
  7. Gregersen I, Skjelland M, Holm S, Holven KB, Krogh-Sørensen K, Russell D, Askevold ET, Dahl CP, Ørn S, Gullestad L, Mollnes TE, Ueland T, Aukrust P, Halvorsen B (2013)
    Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis
    PLoS One, 8 (8), e72769
    PubMed 24023645
  8. Hamre H, Zeller B, Kanellopoulos A, Ruud E, Fosså SD, Loge JH, Aukrust P, Halvorsen B, Mollnes TE, Kiserud CE (2013)
    Serum cytokines and chronic fatigue in adults surviving after childhood leukemia and lymphoma
    Brain Behav Immun, 30, 80-7
    PubMed 23333795
  9. Happonen KE, Saxne T, Jacobsson L, Sturfelt G, Rönnelid J, Mollnes TE, Heinegård D, Turesson C, Blom AM (2013)
    COMP-C3b complexes in rheumatoid arthritis with severe extraarticular manifestations
    J Rheumatol, 40 (12), 2001-5
    PubMed 24187101
  10. Haugaa H, Almaas R, Thorgersen EB, Foss A, Line PD, Sanengen T, Bergmann GB, Ohlin P, Waelgaard L, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2013)
    Clinical experience with microdialysis catheters in pediatric liver transplants
    Liver Transpl, 19 (3), 305-14
    PubMed 23193034
  11. Landsem A, Nielsen EW, Fure H, Christiansen D, Ludviksen JK, Lambris JD, Østerud B, Mollnes TE, Brekke OL (2013)
    C1-inhibitor efficiently inhibits Escherichia coli-induced tissue factor mRNA up-regulation, monocyte tissue factor expression and coagulation activation in human whole blood
    Clin Exp Immunol, 173 (2), 217-29
    PubMed 23607270
  12. Lappegård KT, Hovland A, Pop GA, Mollnes TE (2013)
    Atrial fibrillation: inflammation in disguise?
    Scand J Immunol, 78 (2), 112-9
    PubMed 23672430
  13. Lau C, Gunnarsen KS, Høydahl LS, Andersen JT, Berntzen G, Pharo A, Lindstad JK, Ludviksen JK, Brekke OL, Barratt-Due A, Nielsen EW, Stokes CR, Espevik T, Sandlie I, Mollnes TE (2013)
    Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation
    J Immunol, 191 (9), 4769-77
    PubMed 24062486
  14. Mollnes TE, Nilsson PH (2013)
    Letter to editor
    J Clin Biochem Nutr, 52 (3), 253-4
    PubMed 23704816
  15. Prohászka Z, Munthe-Fog L, Ueland T, Gombos T, Yndestad A, Förhécz Z, Skjoedt MO, Pozsonyi Z, Gustavsen A, Jánoskuti L, Karádi I, Gullestad L, Dahl CP, Askevold ET, Füst G, Aukrust P, Mollnes TE, Garred P (2013)
    Association of ficolin-3 with severity and outcome of chronic heart failure
    PLoS One, 8 (4), e60976
    PubMed 23596511
  16. Salvesen B, Curstedt T, Mollnes TE, Saugstad OD (2013)
    Effects of Natural versus Synthetic Surfactant with SP-B and SP-C Analogs in a Porcine Model of Meconium Aspiration Syndrome
    Neonatology, 105 (2), 128-35
    PubMed 24356240
  17. Schejbel L, Fadnes D, Permin H, Lappegård KT, Garred P, Mollnes TE (2013)
    Primary complement C5 deficiencies - molecular characterization and clinical review of two families
    Immunobiology, 218 (10), 1304-10
    PubMed 23743184
  18. Thorgersen EB, Pischke SE, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Hellerud BC, Mollnes TE (2013)
    Systemic CD14 inhibition attenuates organ inflammation in porcine Escherichia coli sepsis
    Infect Immun, 81 (9), 3173-81
    PubMed 23774598
  19. van Vuuren BJ, Bergseth G, Mollnes TE, Shaw AM (2013)
    Electroluminescent TCC, C3dg and fB/Bb epitope assays for profiling complement cascade activation in vitro using an activated complement serum calibration standard
    J Immunol Methods, 402 (1-2), 50-6
    PubMed 24287422
  20. Øvstebø R, Hellum M, Aass HC, Trøseid AM, Brandtzaeg P, Mollnes TE, Henriksson CE (2013)
    Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood
    Innate Immun, 20 (5), 552-60
    PubMed 24051102

Publications 2012

  1. Almaas R, Hankø E, Mollnes TE, Rootwelt T (2012)
    Dexamethasone reduces bilirubin-induced toxicity and IL-8 and MCP-1 release in human NT2-N neurons
    Brain Res, 1458, 12-7
    PubMed 22546346
  2. Barratt-Due A, Pischke SE, Brekke OL, Thorgersen EB, Nielsen EW, Espevik T, Huber-Lang M, Mollnes TE (2012)
    Bride and groom in systemic inflammation--the bells ring for complement and Toll in cooperation
    Immunobiology, 217 (11), 1047-56
    PubMed 22964230
  3. Barratt-Due A, Sokolov A, Gustavsen A, Hellerud BC, Egge K, Pischke SE, Lindstad JK, Pharo A, Castellheim A, Thorgersen EB, Mollnes TE (2012)
    Polyvalent immunoglobulin significantly attenuated the formation of IL-1β in Escherichia coli-induced sepsis in pigs
    Immunobiology, 218 (5), 683-9
    PubMed 22947599
  4. Bisschops LL, Hoedemaekers CW, Mollnes TE, van der Hoeven JG (2012)
    Rewarming after hypothermia after cardiac arrest shifts the inflammatory balance
    Crit Care Med, 40 (4), 1136-42
    PubMed 22020246
  5. Christiansen D, Brekke OL, Stenvik J, Lambris JD, Espevik T, Mollnes TE (2012)
    Differential effect of inhibiting MD-2 and CD14 on LPS- versus whole E. coli bacteria-induced cytokine responses in human blood
    Adv Exp Med Biol, 946, 237-51
    PubMed 21948372
  6. Granslo HN, Klingenberg C, Fredheim EA, Acharya G, Mollnes TE, Flægstad T (2012)
    Staphylococcus epidermidis biofilms induce lower complement activation in neonates as compared with adults
    Pediatr Res, 73 (3), 294-300
    PubMed 23232670
  7. Harboe M, Garred P, Lindstad JK, Pharo A, Müller F, Stahl GL, Lambris JD, Mollnes TE (2012)
    The role of properdin in zymosan- and Escherichia coli-induced complement activation
    J Immunol, 189 (5), 2606-13
    PubMed 22851705
  8. Haugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Waelgaard L, Pischke SE, Mollnes TE, Inge Tønnessen T (2012)
    Inflammatory markers sampled by microdialysis catheters distinguish rejection from ischemia in liver grafts
    Liver Transpl, 18 (12), 1421-9
    PubMed 22767413
  9. Hovland A, Hardersen R, Nielsen EW, Enebakk T, Christiansen D, Ludviksen JK, Mollnes TE, Lappegård KT (2012)
    Complement profile and activation mechanisms by different LDL apheresis systems
    Acta Biomater, 8 (6), 2288-96
    PubMed 22373816
  10. Hovland A, Lappegård KT, Mollnes TE (2012)
    LDL apheresis and inflammation--implications for atherosclerosis
    Scand J Immunol, 76 (3), 229-36
    PubMed 22670805
  11. Håugaa H, Thorgersen EB, Pharo A, Boberg KM, Foss A, Line PD, Sanengen T, Almaas R, Grindheim G, Pischke SE, Mollnes TE, Tønnessen TI (2012)
    Early bedside detection of ischemia and rejection in liver transplants by microdialysis
    Liver Transpl, 18 (7), 839-49
    PubMed 22407878
  12. Kvarnström A, Sokolov A, Swartling T, Kurlberg G, Mollnes TE, Bengtsson A (2012)
    Alternative pathway activation of complement in laparoscopic and open rectal surgery
    Scand J Immunol, 76 (1), 49-53
    PubMed 22486843
  13. Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lambris JD, Lacík I, Mollnes TE, Espevik T (2012)
    The induction of cytokines by polycation containing microspheres by a complement dependent mechanism
    Biomaterials, 34 (3), 621-30
    PubMed 23103159
  14. Rødland EK, Ueland T, Bjørnsen S, Sagen EL, Dahl CP, Naalsund A, Mollnes TE, Brosstad FR, Müller F, Aukrust P, Frøland SS (2012)
    Systemic biomarkers of inflammation and haemostasis in patients with chronic necrotizing pulmonary aspergillosis
    BMC Infect Dis, 12, 144
    PubMed 22731696
  15. Sokolov A, Hellerud BC, Johannessen EA, Mollnes TE (2012)
    Inflammatory response induced by candidate biomaterials of an implantable microfabricated sensor
    J Biomed Mater Res A, 100 (5), 1142-50
    PubMed 22337626
  16. Sokolov A, Hellerud BC, Tønnessen TI, Johannessen EA, Mollnes TE (2012)
    Activation of coagulation and platelets by candidate membranes of implantable devices in a whole blood model without soluble anticoagulant
    J Biomed Mater Res A, 101 (2), 575-81
    PubMed 22949225
  17. Ørn S, Ueland T, Manhenke C, Sandanger Ø, Godang K, Yndestad A, Mollnes TE, Dickstein K, Aukrust P (2012)
    Increased interleukin-1β levels are associated with left ventricular hypertrophy and remodelling following acute ST segment elevation myocardial infarction treated by primary percutaneous coronary intervention
    J Intern Med, 272 (3), 267-76
    PubMed 22243053

Publications 2011

  1. Barratt-Due A, Johansen HT, Sokolov A, Thorgersen EB, Hellerud BC, Reubsaet JL, Seip KF, Tønnessen TI, Lindstad JK, Pharo A, Castellheim A, Mollnes TE, Nielsen EW (2011)
    The role of bradykinin and the effect of the bradykinin receptor antagonist icatibant in porcine sepsis
    Shock, 36 (5), 517-23
    PubMed 21921836
  2. Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Lissina O, Lambris JD, Nunn MA, Mollnes TE (2011)
    Ornithodoros moubata complement inhibitor is an equally effective C5 inhibitor in pigs and humans
    J Immunol, 187 (9), 4913-9
    PubMed 21964028
  3. Berdal JE, Mollnes TE, Wæhre T, Olstad OK, Halvorsen B, Ueland T, Laake JH, Furuseth MT, Maagaard A, Kjekshus H, Aukrust P, Jonassen CM (2011)
    Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza
    J Infect, 63 (4), 308-16
    PubMed 21781987
  4. Bergseth G, Lambris JD, Mollnes TE, Lappegård KT (2011)
    Artificial surface-induced inflammation relies on complement factor 5: proof from a deficient person
    Ann Thorac Surg, 91 (2), 527-33
    PubMed 21256307
  5. Brekke OL, Hellerud BC, Christiansen D, Fure H, Castellheim A, Nielsen EW, Pharo A, Lindstad JK, Bergseth G, Leslie G, Lambris JD, Brandtzaeg P, Mollnes TE (2011)
    Neisseria meningitidis and Escherichia coli are protected from leukocyte phagocytosis by binding to erythrocyte complement receptor 1 in human blood
    Mol Immunol, 48 (15-16), 2159-69
    PubMed 21839519
  6. Chavez SA, Martinko AJ, Lau C, Pham MN, Cheng K, Bevan DE, Mollnes TE, Yin H (2011)
    Development of β-amino alcohol derivatives that inhibit Toll-like receptor 4 mediated inflammatory response as potential antiseptics
    J Med Chem, 54 (13), 4659-69
    PubMed 21591694
  7. Fredheim EG, Granslo HN, Flægstad T, Figenschau Y, Rohde H, Sadovskaya I, Mollnes TE, Klingenberg C (2011)
    Staphylococcus epidermidis polysaccharide intercellular adhesin activates complement
    FEMS Immunol Med Microbiol, 63 (2), 269-80
    PubMed 22077230
  8. Grimnes G, Beckman H, Lappegård KT, Mollnes TE, Skogen V (2011)
    Recurrent meningococcal sepsis in a presumptive immunocompetent host shown to be complement C5 deficient-a case report
    APMIS, 119 (7), 479-84
    PubMed 21635555
  9. Harboe M, Thorgersen EB, Mollnes TE (2011)
    Advances in assay of complement function and activation
    Adv Drug Deliv Rev, 63 (12), 976-87
    PubMed 21664392
  10. Hovland A, Marcovina S, Hardersen R, Enebakk T, Mollnes TE, Lappegård KT (2011)
    Three different LDL apheresis columns efficiently and equally reduce lipoprotein(a) concentrations in patients with familial hypercholesterolemia and small apolipoprotein(a) particles
    Transfus Apher Sci, 46 (1), 73-6
    PubMed 22206792
  11. Rokstad AM, Brekke OL, Steinkjer B, Ryan L, Kolláriková G, Strand BL, Skjåk-Bræk G, Lacík I, Espevik T, Mollnes TE (2011)
    Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model
    Acta Biomater, 7 (6), 2566-78
    PubMed 21402181
  12. Sokolov A, Hellerud BC, Lambris JD, Johannessen EA, Mollnes TE (2011)
    Activation of polymorphonuclear leukocytes by candidate biomaterials for an implantable glucose sensor
    J Diabetes Sci Technol, 5 (6), 1490-8
    PubMed 22226271
  13. Sokolov A, Hellerud BC, Pharo A, Johannessen EA, Mollnes TE (2011)
    Complement activation by candidate biomaterials of an implantable microfabricated medical device
    J Biomed Mater Res B Appl Biomater, 98 (2), 323-9
    PubMed 21648060
  14. Søyland E, Heier I, Rodríguez-Gallego C, Mollnes TE, Johansen FE, Holven KB, Halvorsen B, Aukrust P, Jahnsen FL, de la Rosa Carrillo D, Krogstad AL, Nenseter MS (2011)
    Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis
    Br J Dermatol, 164 (2), 344-55
    PubMed 21271993
  15. Torfoss D, Sandstad B, Mollnes TE, Høiby EA, Holte H, Bjerner J, Bjøro T, Gaudernack G, Kvalheim G, Kvaløy S (2011)
    The mild inflammatory response in febrile neutropenic lymphoma patients with low risk of complications is more pronounced in patients receiving tobramycin once daily compared with three times daily
    Scand J Immunol, 74 (6), 632-9
    PubMed 21883353
  16. van Kuilenburg J, Lappegård KT, Sexton J, Plesiewicz I, Lap P, Bouwels L, Sprong T, Mollnes TE, Verheugt F, van Heerde WL, Pop GA (2011)
    Persisting thrombin activity in elderly patients with atrial fibrillation on oral anticoagulation is decreased by anti-inflammatory therapy with intensive cholesterol-lowering treatment
    J Clin Lipidol, 5 (4), 273-80
    PubMed 21784372

Publications 2010

  1. Barratt-Due A, Thorgersen EB, Lindstad JK, Pharo A, Brekke OL, Christiansen D, Lambris JD, Mollnes TE (2010)
    Selective inhibition of TNF-alpha or IL-1 beta does not affect E. coli-induced inflammation in human whole blood
    Mol Immunol, 47 (9), 1774-82
    PubMed 20334922
  2. Dalen ML, Alme TN, Munkeby BH, Løberg EM, Pripp AH, Mollnes TE, Rootwelt T, Saugstad OD (2010)
    Early protective effect of hypothermia in newborn pigs after hyperoxic, but not after normoxic, reoxygenation
    J Perinat Med, 38 (5), 545-56
    PubMed 20629493
  3. Eagan TM, Aukrust P, Bakke PS, Damås JK, Skorge TD, Hardie JA, Ueland T, Mollnes TE (2010)
    Systemic mannose-binding lectin is not associated with Chronic Obstructive Pulmonary Disease
    Respir Med, 104 (2), 283-90
    PubMed 19836222
  4. Eagan TM, Aukrust P, Ueland T, Hardie JA, Johannessen A, Mollnes TE, Damås JK, Bakke PS, Wagner PD (2010)
    Body composition and plasma levels of inflammatory biomarkers in COPD
    Eur Respir J, 36 (5), 1027-33
    PubMed 20413541
  5. Eagan TM, Damås JK, Ueland T, Voll-Aanerud M, Mollnes TE, Hardie JA, Bakke PS, Aukrust P (2010)
    Neutrophil gelatinase-associated lipocalin: a biomarker in COPD
    Chest, 138 (4), 888-95
    PubMed 20495108
  6. Granslo HN, Klingenberg C, Fredheim EG, Rønnestad A, Mollnes TE, Flaegstad T (2010)
    Arginine catabolic mobile element is associated with low antibiotic resistance and low pathogenicity in Staphylococcus epidermidis from neonates
    Pediatr Res, 68 (3), 237-41
    PubMed 20703143
  7. Hellerud BC, Nielsen EW, Thorgersen EB, Lindstad JK, Pharo A, Tønnessen TI, Castellheim A, Mollnes TE, Brandtzaeg P (2010)
    Dissecting the effects of lipopolysaccharides from nonlipopolysaccharide molecules in experimental porcine meningococcal sepsis
    Crit Care Med, 38 (6), 1467-74
    PubMed 20400898
  8. Hoedemaekers C, van Deuren M, Sprong T, Pickkers P, Mollnes TE, Klasen I, van der Hoeven J (2010)
    The complement system is activated in a biphasic pattern after coronary artery bypass grafting
    Ann Thorac Surg, 89 (3), 710-6
    PubMed 20172115
  9. Hovland A, Hardersen R, Enebakk T, Mollnes TE, Lappegård KT (2010)
    Patient tolerance regarding different low-density lipoprotein apheresis columns: frequent minor side effects and high patient satisfaction
    J Clin Lipidol, 5 (1), 45-9
    PubMed 21262506
  10. Hovland A, Hardersen R, Mollnes TE, Lappegård KT (2010)
    Selective whole blood lipoprotein apheresis to prevent pancreatitis in drug refractory hypertriglyceridemia
    JOP, 11 (5), 467-9
    PubMed 20818118
  11. Hovland A, Hardersen R, Nielsen EW, Mollnes TE, Lappegård KT (2010)
    Hematologic and hemostatic changes induced by different columns during LDL apheresis
    J Clin Apher, 25 (5), 294-300
    PubMed 20806414
  12. Husebye H, Aune MH, Stenvik J, Samstad E, Skjeldal F, Halaas O, Nilsen NJ, Stenmark H, Latz E, Lien E, Mollnes TE, Bakke O, Espevik T (2010)
    The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes
    Immunity, 33 (4), 583-96
    PubMed 20933442
  13. Johannessen E, Krushinitskaya O, Sokolov A, Philipp H, Hoogerwerf A, Hinderling C, Kautio K, Lenkkeri J, Strömmer E, Kondratyev V, Tønnessen TI, Mollnes TE, Jakobsen H, Zimmer E, Akselsen B (2010)
    Toward an injectable continuous osmotic glucose sensor
    J Diabetes Sci Technol, 4 (4), 882-92
    PubMed 20663452
  14. Kourtzelis I, Markiewski MM, Doumas M, Rafail S, Kambas K, Mitroulis I, Panagoutsos S, Passadakis P, Vargemezis V, Magotti P, Qu H, Mollnes TE, Ritis K, Lambris JD (2010)
    Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis
    Blood, 116 (4), 631-9
    PubMed 20424189
  15. Salvesen B, Stenvik J, Rossetti C, Saugstad OD, Espevik T, Mollnes TE (2010)
    Meconium-induced release of cytokines is mediated by the TRL4/MD-2 complex in a CD14-dependent manner
    Mol Immunol, 47 (6), 1226-34
    PubMed 20092898
  16. Silasi-Mansat R, Zhu H, Popescu NI, Peer G, Sfyroera G, Magotti P, Ivanciu L, Lupu C, Mollnes TE, Taylor FB, Kinasewitz G, Lambris JD, Lupu F (2010)
    Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis
    Blood, 116 (6), 1002-10
    PubMed 20466856
  17. Thiara AS, Andersen VY, Videm V, Mollnes TE, Svennevig K, Hoel TN, Fiane AE (2010)
    Comparable biocompatibility of Phisio- and Bioline-coated cardiopulmonary bypass circuits indicated by the inflammatory response
    Perfusion, 25 (1), 9-16
    PubMed 20172900
  18. Thiara AS, Mollnes TE, Videm V, Andersen VY, Svennevig K, Kolset SO, Fiane AE (2010)
    Biocompatibility and pathways of initial complement pathway activation with Phisio- and PMEA-coated cardiopulmonary bypass circuits during open-heart surgery
    Perfusion, 26 (2), 107-14
    PubMed 21177724
  19. Wester T, Häggblad E, Awan ZA, Barratt-Due A, Kvernebo M, Halvorsen PS, Mollnes TE, Kvernebo K (2010)
    Assessments of skin and tongue microcirculation reveals major changes in porcine sepsis
    Clin Physiol Funct Imaging, 31 (2), 151-8
    PubMed 21087397

Publications 2009

  1. Bexborn F, Engberg AE, Sandholm K, Mollnes TE, Hong J, Nilsson Ekdahl K (2009)
    Hirudin versus heparin for use in whole blood in vitro biocompatibility models
    J Biomed Mater Res A, 89 (4), 951-9
    PubMed 18470919
  2. Castellheim A, Brekke OL, Espevik T, Harboe M, Mollnes TE (2009)
    Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis
    Scand J Immunol, 69 (6), 479-91
    PubMed 19439008
  3. Corallini F, Bossi F, Gonelli A, Tripodo C, Castellino G, Mollnes TE, Tedesco F, Rizzi L, Trotta F, Zauli G, Secchiero P (2009)
    The soluble terminal complement complex (SC5b-9) up-regulates osteoprotegerin expression and release by endothelial cells: implications in rheumatoid arthritis
    Rheumatology (Oxford), 48 (3), 293-8
    PubMed 19168833
  4. Eagan TM, Ueland T, Wagner PD, Hardie JA, Mollnes TE, Damås JK, Aukrust P, Bakke PS (2009)
    Systemic inflammatory markers in COPD: results from the Bergen COPD Cohort Study
    Eur Respir J, 35 (3), 540-8
    PubMed 19643942
  5. Eggum R, Ueland T, Mollnes TE, Videm V, Fiane AE, Aukrust P, Lindberg HL (2009)
    Perfusion temperature, thyroid hormones and inflammation during pediatric cardiac surgery
    Interact Cardiovasc Thorac Surg, 10 (1), 76-80
    PubMed 19822605
  6. Harboe M, Garred P, Karlstrøm E, Lindstad JK, Stahl GL, Mollnes TE (2009)
    The down-stream effects of mannan-induced lectin complement pathway activation depend quantitatively on alternative pathway amplification
    Mol Immunol, 47 (2-3), 373-80
    PubMed 19800125
  7. Hellerud BC, Aase A, Herstad TK, Naess LM, Kristiansen LH, Trøseid AM, Harboe M, Lappegård KT, Brandtzaeg P, Høiby EA, Mollnes TE (2009)
    Critical roles of complement and antibodies in host defense mechanisms against Neisseria meningitidis as revealed by human complement genetic deficiencies
    Infect Immun, 78 (2), 802-9
    PubMed 19933829
  8. Hoel TN, Thiara AS, Videm V, Fiane AE, Mollnes TE, Castellheim A, Svennevig JL (2009)
    In vitro evaluation of PHISIO-coated sets for pediatric cardiac surgery
    Scand Cardiovasc J, 43 (2), 129-35
    PubMed 19294579
  9. Hovland A, Hardersen R, Sexton J, Mollnes TE, Lappegård KT (2009)
    Different inflammatory responses induced by three LDL-lowering apheresis columns
    J Clin Apher, 24 (6), 247-53
    PubMed 19927364
  10. Kåsin JI, Kjekshus J, Aukrust P, Mollnes TE, Wagstaff A (2009)
    A helicopter flight does not induce significant changes in systemic biomarker profiles
    Scand J Clin Lab Invest, 69 (4), 462-74
    PubMed 19333819
  11. Lappegård KT, Christiansen D, Pharo A, Thorgersen EB, Hellerud BC, Lindstad J, Nielsen EW, Bergseth G, Fadnes D, Abrahamsen TG, Høiby EA, Schejbel L, Garred P, Lambris JD, Harboe M, Mollnes TE (2009)
    Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature
    Proc Natl Acad Sci U S A, 106 (37), 15861-6
    PubMed 19717455
  12. Manderson GA, Martin M, Onnerfjord P, Saxne T, Schmidtchen A, Mollnes TE, Heinegård D, Blom AM (2009)
    Interactions of histidine-rich glycoprotein with immunoglobulins and proteins of the complement system
    Mol Immunol, 46 (16), 3388-98
    PubMed 19674792
  13. Martin M, Gottsäter A, Nilsson PM, Mollnes TE, Lindblad B, Blom AM (2009)
    Complement activation and plasma levels of C4b-binding protein in critical limb ischemia patients
    J Vasc Surg, 50 (1), 100-6
    PubMed 19563958
  14. Natvig JB, Mollnes TE (2009)
    Professor emeritus Morten Harboe, one of the founders of Scandinavian Journal of Immunology, turns 80
    Scand. J. Immunol., 69 (6), 469-470
  15. Nielsen EW, Hellerud BC, Thorgersen EB, Castellheim A, Pharo A, Lindstad J, Tønnessen TI, Brandtzaeg P, Mollnes TE (2009)
    A new dynamic porcine model of meningococcal shock
    Shock, 32 (3), 302-9
    PubMed 19174740
  16. Orn S, Breland UM, Mollnes TE, Manhenke C, Dickstein K, Aukrust P, Ueland T (2009)
    The chemokine network in relation to infarct size and left ventricular remodeling following acute myocardial infarction
    Am J Cardiol, 104 (9), 1179-83
    PubMed 19840558
  17. Pedersen ED, Løberg EM, Vege E, Daha MR, Maehlen J, Mollnes TE (2009)
    In situ deposition of complement in human acute brain ischaemia
    Scand J Immunol, 69 (6), 555-62
    PubMed 19439017
  18. Salvesen B, Mollnes TE (2009)
    Pathway-specific complement activity in pigs evaluated with a human functional complement assay
    Mol Immunol, 46 (8-9), 1620-5
    PubMed 19328551
  19. Siezenga MA, Chandie Shaw PK, van der Geest RN, Mollnes TE, Daha MR, Rabelink TJ, Berger SP (2009)
    Enhanced complement activation is part of the unfavourable cardiovascular risk profile in South Asians
    Clin Exp Immunol, 157 (1), 98-103
    PubMed 19659775
  20. Sikkeland LI, Eduard W, Stangeland AM, Thorgersen EB, Haug T, Aukrust P, Halvorsen B, Mollnes TE, Kongerud J (2009)
    Occupational exposure to bacterial single cell protein induces inflammation in lung and blood
    Inhal Toxicol, 21 (8), 674-81
    PubMed 19558225
  21. Sprong T, Mollnes TE, Neeleman C, Swinkels D, Netea MG, van der Meer JW, van Deuren M (2009)
    Mannose-binding lectin is a critical factor in systemic complement activation during meningococcal septic shock
    Clin Infect Dis, 49 (9), 1380-6
    PubMed 19793001
  22. Thorgersen EB, Hellerud BC, Nielsen EW, Barratt-Due A, Fure H, Lindstad JK, Pharo A, Fosse E, Tønnessen TI, Johansen HT, Castellheim A, Mollnes TE (2009)
    CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs
    FASEB J, 24 (3), 712-22
    PubMed 19841036
  23. Thorgersen EB, Ludviksen JK, Lambris JD, Sfyroera G, Nielsen EW, Mollnes TE (2009)
    Anti-inflammatory effects of C1-Inhibitor in porcine and human whole blood are independent of its protease inhibition activity
    Innate Immun, 16 (4), 254-64
    PubMed 19710096
  24. Trøseid M, Lappegård KT, Mollnes TE, Arnesen H, Seljeflot I (2009)
    The effect of exercise on serum levels of interleukin-18 and components of the metabolic syndrome
    Metab Syndr Relat Disord, 7 (6), 579-84
    PubMed 19900154
  25. Ørn S, Manhenke C, Ueland T, Damås JK, Mollnes TE, Edvardsen T, Aukrust P, Dickstein K (2009)
    C-reactive protein, infarct size, microvascular obstruction, and left-ventricular remodelling following acute myocardial infarction
    Eur Heart J, 30 (10), 1180-6
    PubMed 19299430

Publications 2008

  1. Asberg AE, Mollnes TE, Videm V (2008)
    Complement activation by neutrophil granulocytes
    Scand J Immunol, 67 (4), 354-61
    PubMed 18248527
  2. Brekke OL, Christiansen D, Fure H, Pharo A, Fung M, Riesenfeld J, Mollnes TE (2008)
    Combined inhibition of complement and CD14 abolish E. coli-induced cytokine-, chemokine- and growth factor-synthesis in human whole blood
    Mol Immunol, 45 (14), 3804-13
    PubMed 18606453
  3. Castellheim A, Hoel TN, Videm V, Fosse E, Pharo A, Svennevig JL, Fiane AE, Mollnes TE (2008)
    Biomarker profile in off-pump and on-pump coronary artery bypass grafting surgery in low-risk patients
    Ann Thorac Surg, 85 (6), 1994-2002
    PubMed 18498809
  4. Castellheim A, Thorgersen EB, Hellerud BC, Pharo A, Johansen HT, Brosstad F, Gaustad P, Brun H, Fosse E, Tønnessen TI, Nielsen EW, Mollnes TE (2008)
    New biomarkers in an acute model of live Escherichia coli-induced sepsis in pigs
    Scand J Immunol, 68 (1), 75-84
    PubMed 18466195
  5. Dalen ML, Frøyland E, Saugstad OD, Mollnes TE, Rootwelt T (2008)
    Post-hypoxic hypothermia is protective in human NT2-N neurons regardless of oxygen concentration during reoxygenation
    Brain Res, 1259, 80-9
    PubMed 19146835
  6. Eggum R, Ueland T, Mollnes TE, Videm V, Aukrust P, Fiane AE, Lindberg HL (2008)
    Effect of perfusion temperature on the inflammatory response during pediatric cardiac surgery
    Ann Thorac Surg, 85 (2), 611-7
    PubMed 18222275
  7. Harboe M, Mollnes TE (2008)
    The alternative complement pathway revisited
    J Cell Mol Med, 12 (4), 1074-84
    PubMed 18419792
  8. Hellerud BC, Stenvik J, Espevik T, Lambris JD, Mollnes TE, Brandtzaeg P (2008)
    Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation
    Infect Immun, 76 (9), 4183-9
    PubMed 18591229
  9. Lappegård KT, Bergseth G, Riesenfeld J, Pharo A, Magotti P, Lambris JD, Mollnes TE (2008)
    The artificial surface-induced whole blood inflammatory reaction revealed by increases in a series of chemokines and growth factors is largely complement dependent
    J Biomed Mater Res A, 87 (1), 129-35
    PubMed 18085644
  10. Mollnes TE (2008)
    High mobility group box-1 protein--one step closer to the clinic?
    Crit Care, 12 (4), 168
    PubMed 18671827
  11. Mollnes TE, Castellheim A, Lindenskov PH, Salvesen B, Saugstad OD (2008)
    The role of complement in meconium aspiration syndrome
    J Perinatol, 28 Suppl 3, S116-9
    PubMed 19057601
  12. Mollnes TE, Christiansen D, Brekke OL, Espevik T (2008)
    Hypothesis: combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response
    Adv Exp Med Biol, 632, 253-63
    PubMed 19025127
  13. Saethre M, Schneider MK, Lambris JD, Magotti P, Haraldsen G, Seebach JD, Mollnes TE (2008)
    Cytokine secretion depends on Galalpha(1,3)Gal expression in a pig-to-human whole blood model
    J Immunol, 180 (9), 6346-53
    PubMed 18424758
  14. Sagedal S, Thiel S, Hansen TK, Mollnes TE, Rollag H, Hartmann A (2008)
    Impact of the complement lectin pathway on cytomegalovirus disease early after kidney transplantation
    Nephrol Dial Transplant, 23 (12), 4054-60
    PubMed 18577532
  15. Salvesen B, Fung M, Saugstad OD, Mollnes TE (2008)
    Role of complement and CD14 in meconium-induced cytokine formation
    Pediatrics, 121 (3), e496-505
    PubMed 18299306
  16. Salvesen B, Mollnes TE, Saugstad OD (2008)
    Albumin lavage does not improve the outcome of meconium aspiration syndrome
    J Matern Fetal Neonatal Med, 21 (10), 719-25
    PubMed 19012188
  17. Salvesen B, Nielsen EW, Harboe M, Saugstad OD, Mollnes TE (2008)
    Mechanisms of complement activation and effects of C1-inhibitor on the meconium-induced inflammatory reaction in human cord blood
    Mol Immunol, 46 (4), 688-94
    PubMed 18950866
  18. Thorgersen EB, Macagno A, Rossetti C, Mollnes TE (2008)
    Cyanobacterial LPS antagonist (CyP)-a novel and efficient inhibitor of Escherichia coli LPS-induced cytokine response in the pig
    Mol Immunol, 45 (13), 3553-7
    PubMed 18571239
  19. Thorgersen EB, Pharo A, Haverson K, Axelsen AK, Gaustad P, Kotwal GJ, Sfyroera G, Mollnes TE (2008)
    Inhibition of complement and CD14 attenuates the Escherichia coli-induced inflammatory response in porcine whole blood
    Infect Immun, 77 (2), 725-32
    PubMed 19047409
  20. Waelgaard L, Thorgersen EB, Line PD, Foss A, Mollnes TE, Tønnessen TI (2008)
    Microdialysis monitoring of liver grafts by metabolic parameters, cytokine production, and complement activation
    Transplantation, 86 (8), 1096-103
    PubMed 18946348

Publications 2007

  1. Brekke OL, Christiansen D, Fure H, Fung M, Mollnes TE (2007)
    The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human whole blood
    J Leukoc Biol, 81 (6), 1404-13
    PubMed 17389579
  2. Hoel TN, Videm V, Mollnes TE, Saatvedt K, Brosstad F, Fiane AE, Fosse E, Svennevig JL (2007)
    Off-pump cardiac surgery abolishes complement activation
    Perfusion, 22 (4), 251-6
    PubMed 18181513
  3. Markiewski MM, Nilsson B, Ekdahl KN, Mollnes TE, Lambris JD (2007)
    Complement and coagulation: strangers or partners in crime?
    Trends Immunol, 28 (4), 184-92
    PubMed 17336159
  4. Mollnes TE, Jokiranta TS, Truedsson L, Nilsson B, Rodriguez de Cordoba S, Kirschfink M (2007)
    Complement analysis in the 21st century
    Mol Immunol, 44 (16), 3838-49
    PubMed 17768101
  5. Pedersen ED, Aass HC, Rootwelt T, Fung M, Lambris JD, Mollnes TE (2007)
    CD59 efficiently protects human NT2-N neurons against complement-mediated damage
    Scand J Immunol, 66 (2-3), 345-51
    PubMed 17635812
  6. Roestenberg M, McCall M, Mollnes TE, van Deuren M, Sprong T, Klasen I, Hermsen CC, Sauerwein RW, van der Ven A (2007)
    Complement activation in experimental human malaria infection
    Trans R Soc Trop Med Hyg, 101 (7), 643-9
    PubMed 17481680
  7. Saethre M, Baumann BC, Fung M, Seebach JD, Mollnes TE (2007)
    Characterization of natural human anti-non-gal antibodies and their effect on activation of porcine gal-deficient endothelial cells
    Transplantation, 84 (2), 244-50
    PubMed 17667817
  8. Sikkeland LI, Thorgersen EB, Haug T, Mollnes TE (2007)
    Complement activation and cytokine response by BioProtein, a bacterial single cell protein
    Clin Exp Immunol, 148 (1), 146-52
    PubMed 17302729
  9. Ødegård A, Aasland J, Myhre HO, Mollnes TE, Videm V (2007)
    The inflammatory response to stent grafting of the thoracic aorta
    Int Angiol, 26 (3), 219-27
    PubMed 17622202

Publications 2006

  1. Drogset JO, Grøntvedt T, Jessen V, Tegnander A, Mollnes TE, Bergh K (2006)
    Comparison of in vitro and in vivo complement activation by metal and bioabsorbable screws used in anterior cruciate ligament reconstruction
    Arthroscopy, 22 (5), 489-96
    PubMed 16651157
  2. Frøyland E, Pedersen ED, Kvissel AK, Almaas R, Pharo A, Skålhegg BS, Mollnes TE, Rootwelt T (2006)
    Effect of acidosis on IL-8 and MCP-1 during hypoxia and reoxygenation in human NT2-N neurons
    Brain Res, 1113 (1), 64-73
    PubMed 16919250
  3. Harboe M, Garred P, Borgen MS, Stahl GL, Roos A, Mollnes TE (2006)
    Design of a complement mannose-binding lectin pathway-specific activation system applicable at low serum dilutions
    Clin Exp Immunol, 144 (3), 512-20
    PubMed 16734621
  4. Mollnes TE, Kirschfink M (2006)
    Complement analysis in clinic and research
    Adv Exp Med Biol, 586, 361-80
    PubMed 16893084
  5. Mollnes TE, Kirschfink M (2006)
    Strategies of therapeutic complement inhibition
    Mol Immunol, 43 (1-2), 107-21
    PubMed 16011851
  6. Nielsen EW, Waage C, Fure H, Brekke OL, Sfyroera G, Lambris JD, Mollnes TE (2006)
    Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement
    Mol Immunol, 44 (8), 1819-26
    PubMed 17101176
  7. Nilsson B, Ekdahl KN, Mollnes TE, Lambris JD (2006)
    The role of complement in biomaterial-induced inflammation
    Mol Immunol, 44 (1-3), 82-94
    PubMed 16905192
  8. Pedersen ED, Frøyland E, Kvissel AK, Pharo AM, Skålhegg BS, Rootwelt T, Mollnes TE (2006)
    Expression of complement regulators and receptors on human NT2-N neurons--effect of hypoxia and reoxygenation
    Mol Immunol, 44 (9), 2459-68
    PubMed 17116331
  9. Saethre M, Lea T, Borgen MS, Fiane AE, Michaelsen TE, Thorsby E, Haraldsen G, Mollnes TE (2006)
    Human complement-activating immunoglobulin (Ig)G3 antibodies are essential for porcine endothelial cell activation
    Xenotransplantation, 13 (3), 215-23
    PubMed 16756564
  10. Sprong T, Roos D, Weemaes C, Neeleman C, Geesing CL, Mollnes TE, van Deuren M (2006)
    Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections
    Blood, 107 (12), 4865-70
    PubMed 16527897
  11. Thorgersen EB, Ghebremariam YT, Thurman JM, Fung M, Nielsen EW, Holers VM, Kotwal GJ, Mollnes TE (2006)
    Candidate inhibitors of porcine complement
    Mol Immunol, 44 (8), 1827-34
    PubMed 17109963
  12. Ueland T, Espevik T, Kjekshus J, Gullestad L, Omland T, Squire IB, Frøland SS, Mollnes TE, Dickstein K, Aukrust P (2006)
    Mannose binding lectin and soluble Toll-like receptor 2 in heart failure following acute myocardial infarction
    J Card Fail, 12 (8), 659-63
    PubMed 17045187
  13. Waelgaard L, Pharo A, Tønnessen TI, Mollnes TE (2006)
    Microdialysis for monitoring inflammation: efficient recovery of cytokines and anaphylotoxins provided optimal catheter pore size and fluid velocity conditions
    Scand J Immunol, 64 (3), 345-52
    PubMed 16918704

Publications 2005

  1. Castellheim A, Lindenskov PH, Pharo A, Aamodt G, Saugstad OD, Mollnes TE (2005)
    Meconium aspiration syndrome induces complement-associated systemic inflammatory response in newborn piglets
    Scand J Immunol, 61 (3), 217-25
    PubMed 15787738
  2. Fevang B, Mollnes TE, Holm AM, Ueland T, Heggelund L, Damås JK, Aukrust P, Frøland SS (2005)
    Common variable immunodeficiency and the complement system; low mannose-binding lectin levels are associated with bronchiectasis
    Clin Exp Immunol, 142 (3), 576-84
    PubMed 16297171
  3. Fiane AE, Ueland T, Simonsen S, Scott H, Endresen K, Gullestad L, Geiran OR, Haraldsen G, Heggelund L, Andreassen AK, Wergeland R, Frøland S, Aukrust P, Mollnes TE (2005)
    Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischaemia, and rejection after human heart transplantation
    Eur Heart J, 26 (16), 1660-5
    PubMed 15821010
  4. Heggelund L, Mollnes TE, Espevik T, Müller F, Kristiansen KI, Aukrust P, Frøland SS (2005)
    Modulatory effect of mannose-binding lectin on cytokine responses: possible roles in HIV infection
    Eur J Clin Invest, 35 (12), 765-70
    PubMed 16313253
  5. Hognestad A, Endresen K, Wergeland R, Mellembakken JR, Mollnes TE, Omland T, Kjekshus JK, Aukrust P, Andreassen AK (2005)
    Inflammatory response and re-stenosis after percutaneous coronary intervention in heart transplant recipients and patients with native atherosclerosis
    J Heart Lung Transplant, 24 (8), 1026-32
    PubMed 16102437
  6. Lappegård KT, Bergseth G, Riesenfeld J, Sexton J, Mollnes TE (2005)
    Role of granulocytes and monocytes in the polyvinyl chloride-induced synthesis of interleukin 8, monocyte chemoattractant protein 1, and leukotriene B4
    J Biomed Mater Res A, 74 (2), 230-6
    PubMed 15962266
  7. Lappegård KT, Riesenfeld J, Brekke OL, Bergseth G, Lambris JD, Mollnes TE (2005)
    Differential effect of heparin coating and complement inhibition on artificial surface-induced eicosanoid production
    Ann Thorac Surg, 79 (3), 917-23
    PubMed 15734405
  8. Sørlie D, Wisborg T, Wählby L, Wilskow A, Mollnes TE, Gamnes J, Arnesen E (2005)
    [A programme for boosting medical research in North Norway, 1992-2001]
    Tidsskr Nor Laegeforen, 125 (4), 449-50
    PubMed 15742020
  9. Trøseid M, Lappegård KT, Mollnes TE, Arnesen H, Seljeflot I (2005)
    Changes in serum levels of E-selectin correlate to improved glycaemic control and reduced obesity in subjects with the metabolic syndrome
    Scand J Clin Lab Invest, 65 (4), 283-90
    PubMed 16076683

Publications 2004

  1. Bossi F, Fischetti F, Pellis V, Bulla R, Ferrero E, Mollnes TE, Regoli D, Tedesco F (2004)
    Platelet-activating factor and kinin-dependent vascular leakage as a novel functional activity of the soluble terminal complement complex
    J Immunol, 173 (11), 6921-7
    PubMed 15557188
  2. Castellheim A, Pharo A, Fung M, Saugstad OD, Mollnes TE (2004)
    Complement C5a is a key mediator of meconium-induced neutrophil activation
    Pediatr Res, 57 (2), 242-7
    PubMed 15585680
  3. Harboe M, Ulvund G, Vien L, Fung M, Mollnes TE (2004)
    The quantitative role of alternative pathway amplification in classical pathway induced terminal complement activation
    Clin Exp Immunol, 138 (3), 439-46
    PubMed 15544620
  4. Heggelund L, Flo T, Berg K, Lien E, Mollnes TE, Ueland T, Aukrust P, Espevik T, Frøland SS (2004)
    Soluble toll-like receptor 2 in HIV infection: association with disease progression
    AIDS, 18 (18), 2437-9
    PubMed 15622324
  5. Hoel TN, Videm V, Baksaas ST, Mollnes TE, Brosstad F, Svennevig JL (2004)
    Comparison of a Duraflo II-coated cardiopulmonary bypass circuit and a trillium-coated oxygenator during open-heart surgery
    Perfusion, 19 (3), 177-84
    PubMed 15298426
  6. Lappegård KT, Fung M, Bergseth G, Riesenfeld J, Lambris JD, Videm V, Mollnes TE (2004)
    Effect of complement inhibition and heparin coating on artificial surface-induced leukocyte and platelet activation
    Ann Thorac Surg, 77 (3), 932-41
    PubMed 14992902
  7. Lappegård KT, Fung M, Bergseth G, Riesenfeld J, Mollnes TE (2004)
    Artificial surface-induced cytokine synthesis: effect of heparin coating and complement inhibition
    Ann Thorac Surg, 78 (1), 38-44; discussion 44-5
    PubMed 15223398
  8. Lappegård KT, Hvassing T, Mollnes TE (2004)
    Statin drugs do not affect serum complement activation in vitro
    Scand J Immunol, 60 (1-2), 178-83
    PubMed 15238087
  9. Lindenskov PH, Castellheim A, Aamodt G, Saugstad OD, Mollnes TE (2004)
    Complement activation reflects severity of meconium aspiration syndrome in newborn pigs
    Pediatr Res, 56 (5), 810-7
    PubMed 15347770
  10. Pedersen ED, Waje-Andreassen U, Vedeler CA, Aamodt G, Mollnes TE (2004)
    Systemic complement activation following human acute ischaemic stroke
    Clin Exp Immunol, 137 (1), 117-22
    PubMed 15196251
  11. Seelen MA, Roos A, Wieslander J, Mollnes TE, Sjöholm AG, Wurzner R, Loos M, Tedesco F, Sim RB, Garred P, Alexopoulos E, Turner MW, Daha MR (2004)
    Functional analysis of the classical, alternative, and MBL pathways of the complement system: standardization and validation of a simple ELISA
    J Immunol Methods, 296 (1-2), 187-98
    PubMed 15680163
  12. Sprong T, Møller AS, Bjerre A, Wedege E, Kierulf P, van der Meer JW, Brandtzaeg P, van Deuren M, Mollnes TE (2004)
    Complement activation and complement-dependent inflammation by Neisseria meningitidis are independent of lipopolysaccharide
    Infect Immun, 72 (6), 3344-9
    PubMed 15155639
  13. Sund S, Reisaeter AV, Scott H, Mollnes TE, Hovig T (2004)
    Glomerular monocyte/macrophage influx correlates strongly with complement activation in 1-week protocol kidney allograft biopsies
    Clin Nephrol, 62 (2), 121-30
    PubMed 15356969
  14. Trøseid M, Lappegård KT, Claudi T, Damås JK, Mørkrid L, Brendberg R, Mollnes TE (2004)
    Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome
    Eur Heart J, 25 (4), 349-55
    PubMed 14984925

Publications 2003

  1. Castellheim A, Lindenskov PH, Pharo A, Fung M, Saugstad OD, Mollnes TE (2003)
    Meconium is a potent activator of complement in human serum and in piglets
    Pediatr Res, 55 (2), 310-8
    PubMed 14605246
  2. Fiane AE, Videm V, Lingaas PS, Heggelund L, Nielsen EW, Geiran OR, Fung M, Mollnes TE (2003)
    Mechanism of complement activation and its role in the inflammatory response after thoracoabdominal aortic aneurysm repair
    Circulation, 108 (7), 849-56
    PubMed 12900342
  3. Fung M, Lu M, Fure H, Sun W, Sun C, Shi NY, Dou Y, Su J, Swanson X, Mollnes TE (2003)
    Pre-neutralization of C5a-mediated effects by the monoclonal antibody 137-26 reacting with the C5a moiety of native C5 without preventing C5 cleavage
    Clin Exp Immunol, 133 (2), 160-9
    PubMed 12869020
  4. Heggelund L, Mollnes TE, Ueland T, Christophersen B, Aukrust P, Frøland SS (2003)
    Mannose-binding lectin in HIV infection: relation to disease progression and highly active antiretroviral therapy
    J Acquir Immune Defic Syndr, 32 (4), 354-61
    PubMed 12640191
  5. Kirschfink M, Mollnes TE (2003)
    Modern complement analysis
    Clin Diagn Lab Immunol, 10 (6), 982-9
    PubMed 14607856
  6. Mollnes TE (2003)
    Measurement of complement activation
    Methods Mol Biol, 225, 69-75
    PubMed 12769475
  7. Mollnes TE, Fiane AE (2003)
    Perspectives on complement in xenotransplantation
    Mol Immunol, 40 (2-4), 135-43
    PubMed 12914819
  8. Risnes I, Ueland T, Aukrust P, Lundblad R, Baksaas ST, Mollnes TE, Svennevig JL (2003)
    Complement activation and cytokine and chemokines release during mediastinitis
    Ann Thorac Surg, 75 (3), 981-5
    PubMed 12645727
  9. Risnes I, Ueland T, Lundblad R, Mollnes TE, Baksaas ST, Aukrust P, Svennevig JL (2003)
    Changes in the cytokine network and complement parameters during open heart surgery
    Interact Cardiovasc Thorac Surg, 2 (1), 19-24
    PubMed 17669979
  10. Solheim BG, Flesland O, Brosstad F, Mollnes TE, Seghatchian J (2003)
    Improved preservation of coagulation factors after pre-storage leukocyte depletion of whole blood
    Transfus Apher Sci, 29 (2), 133-9
    PubMed 12941351
  11. Sprong T, Brandtzaeg P, Fung M, Pharo AM, Høiby EA, Michaelsen TE, Aase A, van der Meer JW, van Deuren M, Mollnes TE (2003)
    Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis
    Blood, 102 (10), 3702-10
    PubMed 12881318
  12. Sund S, Hovig T, Reisaeter AV, Scott H, Bentdal Ø, Mollnes TE (2003)
    Complement activation in early protocol kidney graft biopsies after living-donor transplantation
    Transplantation, 75 (8), 1204-13
    PubMed 12717204
  13. Tølløfsrud S, Noddeland H, Svennevig JL, Bentsen G, Mollnes TE, Solheim BG (2003)
    Universal fresh frozen plasma (Uniplas): a safe product in open-heart surgery
    Intensive Care Med, 29 (10), 1736-43
    PubMed 12955185

Publications 2002

  1. Bjerre A, Brusletto B, Mollnes TE, Fritzsønn E, Rosenqvist E, Wedege E, Namork E, Kierulf P, Brandtzaeg P (2002)
    Complement activation induced by purified Neisseria meningitidis lipopolysaccharide (LPS), outer membrane vesicles, whole bacteria, and an LPS-free mutant
    J Infect Dis, 185 (2), 220-8
    PubMed 11807696
  2. Evgenov OV, Evgenov NV, Mollnes TE, Bjertnaes LJ (2002)
    Methylene blue reduces pulmonary oedema and cyclo-oxygenase products in endotoxaemic sheep
    Eur Respir J, 20 (4), 957-64
    PubMed 12412689
  3. Fiane AE, Geiran OR, Mollnes TE (2002)
    [Ethical aspects of xenotransplantation]
    Tidsskr Nor Laegeforen, 122 (4), 397-400
    PubMed 11915670
  4. Mollnes TE, Brekke OL, Fung M, Fure H, Christiansen D, Bergseth G, Videm V, Lappegård KT, Köhl J, Lambris JD (2002)
    Essential role of the C5a receptor in E coli-induced oxidative burst and phagocytosis revealed by a novel lepirudin-based human whole blood model of inflammation
    Blood, 100 (5), 1869-77
    PubMed 12176911
  5. Mollnes TE, Fiane AE (2002)
    Role of complement in xenotransplantation
    Allergy, 57 Suppl 72, 75-8
    PubMed 12144560
  6. Mollnes TE, Song WC, Lambris JD (2002)
    Complement in inflammatory tissue damage and disease
    Trends Immunol, 23 (2), 61-4
    PubMed 11929126
  7. Nielsen EW, Mollnes TE, Harlan JM, Winn RK (2002)
    C1-inhibitor reduces the ischaemia-reperfusion injury of skeletal muscles in mice after aortic cross-clamping
    Scand J Immunol, 56 (6), 588-92
    PubMed 12472670
  8. Saethre M, Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Platt JL, Mollnes TE (2002)
    Human serum-induced porcine endothelial cell E-selectin expression is associated with IgG3 and IgM anti-Gal antibodies
    Xenotransplantation, 9 (5), 350-8
    PubMed 12199866
  9. Scholz T, Solberg R, Okkenhaug C, Videm V, Gallimore MJ, Mathisen O, Mollnes TE, Bergan A, Søreide O, Klintmalm GB, Aasen AO (2002)
    The significance of heparin-coated veno-venous bypass circuits in liver transplantation
    Perfusion, 17 (1), 45-50
    PubMed 11817529

Publications 2001

  1. Aukrust P, Gullestad L, Lappegård KT, Ueland T, Aass H, Wikeby L, Simonsen S, Frøland SS, Mollnes TE (2001)
    Complement activation in patients with congestive heart failure: effect of high-dose intravenous immunoglobulin treatment
    Circulation, 104 (13), 1494-500
    PubMed 11571242
  2. Kirschfink M, Mollnes TE (2001)
    C1-inhibitor: an anti-inflammatory reagent with therapeutic potential
    Expert Opin Pharmacother, 2 (7), 1073-83
    PubMed 11583058
  3. Lamark T, Ingebrigtsen M, Bjørnstad C, Melkko T, Mollnes TE, Nielsen EW (2001)
    Expression of active human C1 inhibitor serpin domain in Escherichia coli
    Protein Expr Purif, 22 (2), 349-58
    PubMed 11437612
  4. Mellembakken JR, Høgåsen K, Mollnes TE, Hack CE, Abyholm T, Videm V (2001)
    Increased systemic activation of neutrophils but not complement in preeclampsia
    Obstet Gynecol, 97 (3), 371-4
    PubMed 11239639
  5. Scholz T, Solberg R, Okkenhaug C, Videm V, Gallimore MJ, Mathisen O, Pedersen T, Mollnes TE, Bergan A, Søreide O, Klintmalm GB, Aasen AO (2001)
    Veno-venous bypass in liver transplantation: heparin-coated perfusion circuits reduce the activation of humoral defense systems in an in vitro model
    Perfusion, 16 (4), 285-92
    PubMed 11486847
  6. Sølvik UO, Haraldsen G, Fiane AE, Boretti E, Thorsby E, Mollnes TE (2001)
    C1-inhibitor attenuates human serum induced E-selectin expression of pig aortic endothelial cells
    Transplant Proc, 33 (1-2), 789-90
    PubMed 11267073
  7. Sølvik UØ, Haraldsen G, Fiane AE, Boretti E, Lambris JD, Fung M, Thorsby E, Mollnes TE (2001)
    Human serum-induced expression of E-selectin on porcine aortic endothelial cells in vitro is totally complement mediated
    Transplantation, 72 (12), 1967-73
    PubMed 11773897
  8. Ulvestad E, Berentsen S, Mollnes TE (2001)
    Acute phase haemolysis in chronic cold agglutinin disease
    Scand J Immunol, 54 (1-2), 239-42
    PubMed 11439172

Publications 2000

  1. Bergseth G, Lappegård KT, Videm V, Mollnes TE (2000)
    A novel enzyme immunoassay for plasma thrombospondin. Comparison with beta-thromboglobulin as platelet activation marker in vitro and in vivo
    Thromb Res, 99 (1), 41-50
    PubMed 10904102
  2. Fiane AE, Mollnes TE, Degré M (2000)
    Pig endogenous retrovirus--a threat to clinical xenotransplantation?
    APMIS, 108 (4), 241-50
    PubMed 10843410
  3. Fiane AE, Videm V, Lambris JD, Geiran OR, Svennevig JL, Mollnes TE (2000)
    Modulation of fluid-phase complement activation inhibits hyperacute rejection in a porcine-to-human xenograft model
    Transplant Proc, 32 (5), 899-900
    PubMed 10936264
  4. Myhr KM, Sadallah S, Mollnes TE, Meri S, Nyland HI, Schifferli J, Vedeler CA (2000)
    Interferon-alpha2a effects on complement activation and regulation in MS patients
    Acta Neurol Scand, 101 (1), 30-5
    PubMed 10660149
  5. Odegård A, Lundbom J, Myhre HO, Hatlinghus S, Bergh K, Waage A, Bjerve KS, Mollnes TE, Aadahl P, Lie TA, Videm V (2000)
    The inflammatory response following treatment of abdominal aortic aneurysms: a comparison between open surgery and endovascular repair
    Eur J Vasc Endovasc Surg, 19 (5), 536-44
    PubMed 10828237
  6. Olsson P, Sanchez J, Mollnes TE, Riesenfeld J (2000)
    On the blood compatibility of end-point immobilized heparin
    J Biomater Sci Polym Ed, 11 (11), 1261-73
    PubMed 11263812

Publications 1999

  1. Baksaas ST, Flom-Halvorsen HI, Ovrum E, Videm V, Mollnes TE, Brosstad F, Svennevig JL (1999)
    Leucocyte filtration during cardiopulmonary reperfusion in coronary artery bypass surgery
    Perfusion, 14 (2), 107-17
    PubMed 10338322
  2. Baksaas ST, Videm V, Fosse E, Karlsen H, Pedersen T, Mollnes TE, Hagve TA, Svennevig JL (1999)
    In vitro evaluation of new surface coatings for extracorporeal circulation
    Perfusion, 14 (1), 11-9
    PubMed 10074642
  3. Baksaas ST, Videm V, Pedersen T, Karlsen H, Mollnes TE, Brosstad F, Svennevig JL (1999)
    Comparison of three oxygenator-coated and one total-circuit-coated extracorporeal devices
    Perfusion, 14 (2), 119-27
    PubMed 10338323
  4. Fiane AE, Mollnes TE (1999)
    [Transplantation from animal to man]
    Tidsskr Nor Laegeforen, 119 (28), 4213-8
    PubMed 10668386
  5. Fiane AE, Mollnes TE, Videm V, Hovig T, Høgåsen K, Mellbye OJ, Spruce L, Moore WT, Sahu A, Lambris JD (1999)
    Prolongation of ex vivo-perfused pig xenograft survival by the complement inhibitor Compstatin
    Transplant Proc, 31 (1-2), 934-5
    PubMed 10083413
  6. Fiane AE, Mollnes TE, Videm V, Hovig T, Høgåsen K, Mellbye OJ, Spruce L, Moore WT, Sahu A, Lambris JD (1999)
    Compstatin, a peptide inhibitor of C3, prolongs survival of ex vivo perfused pig xenografts
    Xenotransplantation, 6 (1), 52-65
    PubMed 10355733
  7. Fiane AE, Videm V, Johansen HT, Mellbye OJ, Nielsen EW, Mollnes TE (1999)
    C1-inhibitor attenuates hyperacute rejection and inhibits complement, leukocyte and platelet activation in an ex vivo pig-to-human perfusion model
    Immunopharmacology, 42 (1-3), 231-43
    PubMed 10408384
  8. Fiane AE, Videm V, Mollnes TE, Høgâsen K, Hovig T (1999)
    Inhibition of platelet aggregation by the GPIIb/IIIa antagonist reopro does not significantly prolong xenograft survival in an ex vivo model
    Transpl Int, 12 (5), 323-33
    PubMed 10551997
  9. Krohn CD, Reikerås O, Mollnes TE (1999)
    Complement activation and increased systemic and pulmonary vascular resistance indices during infusion of postoperatively drained untreated blood
    Br J Anaesth, 82 (1), 47-51
    PubMed 10325835
  10. Mollnes TE, Fiane AE (1999)
    Xenotransplantation: how to overcome the complement obstacle?
    Mol Immunol, 36 (4-5), 269-76
    PubMed 10403480
  11. Mollnes TE, Haga HJ, Brun JG, Nielsen EW, Sjöholm A, Sturfeldt G, Mårtensson U, Bergh K, Rekvig OP (1999)
    Complement activation in patients with systemic lupus erythematosus without nephritis
    Rheumatology (Oxford), 38 (10), 933-40
    PubMed 10534542
  12. Mollnes TE, Videm V, Christiansen D, Bergseth G, Riesenfeld J, Hovig T (1999)
    Platelet compatibility of an artificial surface modified with functionally active heparin
    Thromb Haemost, 82 (3), 1132-6
    PubMed 10494777
  13. Neeleman C, Geelen SP, Aerts PC, Daha MR, Mollnes TE, Roord JJ, Posthuma G, van Dijk H, Fleer A (1999)
    Resistance to both complement activation and phagocytosis in type 3 pneumococci is mediated by the binding of complement regulatory protein factor H
    Infect Immun, 67 (9), 4517-24
    PubMed 10456894
  14. Videm V, Mollnes TE, Bergh K, Fosse E, Mohr B, Hagve TA, Aasen AO, Svennevig JL (1999)
    Heparin-coated cardiopulmonary bypass equipment. II. Mechanisms for reduced complement activation in vivo
    J Thorac Cardiovasc Surg, 117 (4), 803-9
    PubMed 10096977
  15. Videm V, Mollnes TE, Fosse E, Mohr B, Bergh K, Hagve TA, Aasen AO, Svennevig JL (1999)
    Heparin-coated cardiopulmonary bypass equipment. I. Biocompatibility markers and development of complications in a high-risk population
    J Thorac Cardiovasc Surg, 117 (4), 794-802
    PubMed 10096976

Publications 1998

  1. Arnestad JP, Hyllner M, Bengtson JP, Tylman M, Mollnes TE, Bengtsson A (1998)
    Removal of activated complement from shed blood: comparison of high- and low-dilutional haemofiltration
    Acta Anaesthesiol Scand, 42 (7), 811-5
    PubMed 9698958
  2. Baksaas ST, Videm V, Mollnes TE, Tølløfsrud S, Hetland G, Pedersen T, Svennevig JL (1998)
    Leucocyte filtration during cardiopulmonary bypass hardly changed leucocyte counts and did not influence myeloperoxidase, complement, cytokines or platelets
    Perfusion, 13 (6), 429-36
    PubMed 9881390
  3. Bengtsson A, Redl H, Schlag G, Högåsen K, Götze O, Mollnes TE (1998)
    Anti-TNF treatment of baboons with sepsis reduces TNF-alpha, IL-6 and IL-8, but not the degree of complement activation
    Scand J Immunol, 48 (5), 509-14
    PubMed 9822260
  4. Fiane AE, Videm V, Foerster A, Scholz T, Perdersen TH, Karlsen H, Svennevig JL, Geiran OR, Aasen AO, Mollnes TE (1998)
    An ex vivo perfusion model to evaluate hyperacute rejection in a discordant pig-to-human combination
    Eur Surg Res, 30 (5), 341-51
    PubMed 9731103
  5. Fiane AE, Videm V, Mellbye OJ, Foerster A, Geiran OR, Gladhaug IP, Svennevig JL, Mollnes TE (1998)
    Immunoglobulin prolongs survival of pig kidneys perfused ex vivo with human blood
    Scand J Immunol, 47 (6), 568-74
    PubMed 9652825
  6. Fosse E, Pillgram-Larsen J, Svennevig JL, Nordby C, Skulberg A, Mollnes TE, Abdelnoor M (1998)
    Complement activation in injured patients occurs immediately and is dependent on the severity of the trauma
    Injury, 29 (7), 509-14
    PubMed 10193492
  7. Hetland G, Mollnes TE, Bergh K, Høgåsen K, Bergerud UE, Solheim BG (1998)
    Effect of filtration and storage of platelet concentrates on the production of the chemotaxins C5a, interleukin 8, tumor necrosis factor alpha, and leukotriene B4
    Transfusion, 38 (1), 16-23
    PubMed 9482389
  8. Høgåsen K, Mollnes TE, Nürnberger W, Pausa M, Fukumori Y, Tedesco F (1998)
    Characterization of soluble terminal complement complex assembled in C8beta-deficient plasma and serum
    Scand J Immunol, 48 (3), 261-8
    PubMed 9743210
  9. Krohn CD, Reikerås O, Mollnes TE, Aasen AO (1998)
    Complement activation and release of interleukin-6 and tumour necrosis factor-alpha in drained and systemic blood after major orthopaedic surgery
    Eur J Surg, 164 (2), 103-8
    PubMed 9537716
  10. Mollnes TE (1998)
    Complement and biocompatibility
    Vox Sang, 74 Suppl 2, 303-7
    PubMed 9704460
  11. Mollnes TE, Høgåsen K, De Carolis C, Vaquero E, Nielsen EW, Fontana L, Perricone R (1998)
    High-dose intravenous immunoglobulin treatment activates complement in vivo
    Scand J Immunol, 48 (3), 312-7
    PubMed 9743219
  12. Nielsen EW, Fure H, Winge P, Mollnes TE (1998)
    Identification of a C-->T mutation in the reactive-site coding region of the C1-inhibitor gene and its detection by an improved mutation-specific polymerase chain reaction method
    Scand J Immunol, 47 (3), 273-6
    PubMed 9519866
  13. Nordang L, Laurent C, Mollnes TE (1998)
    Complement activation in sudden deafness
    Arch Otolaryngol Head Neck Surg, 124 (6), 633-6
    PubMed 9639471
  14. Solheim BG, Bergerud UE, Kjeldsen-Kragh J, Brosstad F, Mollnes TE, Högman CF, Eriksson L, Schutz R (1998)
    Improved blood preservation with 0.5CPD erythro-sol. Coagulation factor VIII activity and erythrocyte quality after delayed separation of blood
    Vox Sang, 74 (3), 168-75
    PubMed 9595644

Publications 1997

  1. Baksaas ST, Videm V, Mollnes TE, Pedersen T, Karlsen H, Svennevig JL (1997)
    Effects on complement, granulocytes and platelets of a leukocyte-depletion filter during in vitro extracorporeal circulation
    Scand Cardiovasc J, 31 (2), 73-7
    PubMed 9211593
  2. Fosse E, Thelin S, Svennevig JL, Jansen P, Mollnes TE, Hack E, Venge P, Moen O, Brockmeier V, Dregelid E, Haldén E, Hagman L, Videm V, Pedersen T, Mohr B (1997)
    Duraflo II coating of cardiopulmonary bypass circuits reduces complement activation, but does not affect the release of granulocyte enzymes : a European multicentre study
    Eur J Cardiothorac Surg, 11 (2), 320-7
    PubMed 9080162
  3. Fure H, Nielsen EW, Hack CE, Mollnes TE (1997)
    A neoepitope-based enzyme immunoassay for quantification of C1-inhibitor in complex with C1r and C1s
    Scand J Immunol, 46 (6), 553-7
    PubMed 9420617
  4. Garred P, Mollnes TE (1997)
    Immobilized heparin inhibits the increase in leukocyte surface expression of adhesion molecules
    Artif Organs, 21 (4), 293-9
    PubMed 9096801
  5. Hetland G, Moen O, Bergh K, Högäsen K, Hack CE, Mollnes TE, Fosse E (1997)
    Both plasma- and leukocyte-associated C5a are essential for assessment of C5a generation in vivo
    Ann Thorac Surg, 63 (4), 1076-80
    PubMed 9124908
  6. Homann C, Varming K, Høgåsen K, Mollnes TE, Graudal N, Thomsen AC, Garred P (1997)
    Acquired C3 deficiency in patients with alcoholic cirrhosis predisposes to infection and increased mortality
    Gut, 40 (4), 544-9
    PubMed 9176087
  7. Moen O, Høgåsen K, Fosse E, Dregelid E, Brockmeier V, Venge P, Harboe M, Mollnes TE (1997)
    Attenuation of changes in leukocyte surface markers and complement activation with heparin-coated cardiopulmonary bypass
    Ann Thorac Surg, 63 (1), 105-11
    PubMed 8993250
  8. Mollnes TE (1997)
    Biocompatibility: complement as mediator of tissue damage and as indicator of incompatibility
    Exp Clin Immunogenet, 14 (1), 24-9
    PubMed 9187920
  9. Mollnes TE, Andreassen IH, Høgåsen K, Hack CE, Harboe M (1997)
    Effect of whole and fractionated intravenous immunoglobulin on complement in vitro
    Mol Immunol, 34 (10), 719-29
    PubMed 9430199
  10. Pedersen TH, Videm V, Svennevig JL, Karlsen H, Ostbakk RW, Jensen O, Mollnes TE (1997)
    Extracorporeal membrane oxygenation using a centrifugal pump and a servo regulator to prevent negative inlet pressure
    Ann Thorac Surg, 63 (5), 1333-9
    PubMed 9146324
  11. Samdal F, Mollnes TE, Amland PF, Truedsson L (1997)
    Modest release of adipsin/factor D by liposuction when using the superwet or tumescent technique
    Plast Reconstr Surg, 99 (6), 1591-4; discussion 1595-6
    PubMed 9145127

Publications 1996

  1. Bengtsson A, Redl H, Schlag G, Mollnes TE, Högåsen K (1996)
    Effects on complement activation and cytokine (TNF-alpha and IL-8) release of infusion of anti-TNF-antibodies or a xanthine derivative (HWA 138) in septic baboons
    Acta Anaesthesiol Scand, 40 (2), 244-9
    PubMed 8848926
  2. Brandtzaeg P, Høgåsen K, Kierulf P, Mollnes TE (1996)
    The excessive complement activation in fulminant meningococcal septicemia is predominantly caused by alternative pathway activation
    J Infect Dis, 173 (3), 647-55
    PubMed 8627028
  3. Bringeland EA, Ramstad K, Nielsen EW, Andersen L, Amundsen W, Mollnes TE (1996)
    [Reduced blood utilization in hip arthroplasty. Introduction of a blood preservation program]
    Tidsskr Nor Laegeforen, 116 (1), 30-3
    PubMed 8553331
  4. Gong J, Larsson R, Ekdahl KN, Mollnes TE, Nilsson U, Nilsson B (1996)
    Tubing loops as a model for cardiopulmonary bypass circuits: both the biomaterial and the blood-gas phase interfaces induce complement activation in an in vitro model
    J Clin Immunol, 16 (4), 222-9
    PubMed 8840224
  5. Høgåsen K, Homann C, Mollnes TE, Graudal N, Høgåsen AK, Hasselqvist P, Thomsen AC, Garred P (1996)
    Serum clusterin and vitronectin in alcoholic cirrhosis
    Liver, 16 (2), 140-6
    PubMed 8740849
  6. Mellbye OJ, Shen Y, Høgåsen K, Mollnes TE, Førre O (1996)
    Adhesion molecule expression and complement activation in vessel walls in synovial tissue from patients with chronic inflammatory joint disease
    Clin Rheumatol, 15 (5), 441-7
    PubMed 8894356
  7. Moen O, Fosse E, Bråten J, Andersson C, Høgåsen K, Mollnes TE, Venge P, Kierulf P (1996)
    Differences in blood activation related to roller/centrifugal pumps and heparin-coated/uncoated surfaces in a cardiopulmonary bypass model circuit
    Perfusion, 11 (2), 113-23
    PubMed 8740352
  8. Moen O, Fosse E, Dregelid E, Brockmeier V, Andersson C, Høgåsen K, Venge P, Mollnes TE, Kierulf P (1996)
    Centrifugal pump and heparin coating improves cardiopulmonary bypass biocompatibility
    Ann Thorac Surg, 62 (4), 1134-40
    PubMed 8823102
  9. Mollnes TE, Harboe M (1996)
    Clinical immunology
    BMJ, 312 (7044), 1465-9
    PubMed 8664630
  10. Nielsen EW, Gran JT, Straume B, Mellbye OJ, Johansen HT, Mollnes TE (1996)
    Hereditary angio-oedema: new clinical observations and autoimmune screening, complement and kallikrein-kinin analyses
    J Intern Med, 239 (2), 119-30
    PubMed 8568479
  11. Nielsen EW, Johansen HT, Høgåsen K, Wuillemin W, Hack CE, Mollnes TE (1996)
    Activation of the complement, coagulation, fibrinolytic and kallikrein-kinin systems during attacks of hereditary angioedema
    Scand J Immunol, 44 (2), 185-92
    PubMed 8711433
  12. Nielsen EW, Johansen HT, Høgåsen K, Wuillemin W, Hack CE, Mollnes TE (1996)
    Activation of the complement, coagulation, fibrinolytic and kallikrein-kinin systems during attacks of hereditary angioedema
    Immunopharmacology, 33 (1-3), 359-60
    PubMed 8856186
  13. Ovrum E, Fosse E, Mollnes TE, Am Holen E, Tangen G, Abdelnoor M, Ringdal MA, Oystese R, Venge P (1996)
    Complete heparin-coated cardiopulmonary bypass and low heparin dose reduce complement and granulocyte activation
    Eur J Cardiothorac Surg, 10 (1), 54-60
    PubMed 8776186
  14. Radillo O, Nocera A, Leprini A, Barocci S, Mollnes TE, Pocecco M, Pausa M, Valente U, Betterle C, Tedesco F (1996)
    Complement-fixing islet cell antibodies in type-1 diabetes can trigger the assembly of the terminal complement complex on human islet cells and are potentially cytotoxic
    Clin Immunol Immunopathol, 79 (3), 217-23
    PubMed 8635278
  15. Svennevig JL, Tølløfsrud S, Kongsgaard U, Noddeland H, Mohr B, Ozer M, Mollnes TE (1996)
    Complement activation during and after open-heart surgery is only marginally affected by the choice of fluid for volume replacement
    Perfusion, 11 (4), 326-32
    PubMed 8884861
  16. Saatvedt K, Lindberg H, Geiran OR, Michelsen S, Pedersen T, Seem E, Mollnes TE (1996)
    Ultrafiltration after cardiopulmonary bypass in children: effects on hemodynamics, cytokines and complement
    Cardiovasc Res, 31 (4), 596-602
    PubMed 8689651
  17. Saatvedt K, Lindberg H, Michelsen S, Mollnes TE (1996)
    Release of interleukin 6 and activation of complement during and after paediatric cardiopulmonary bypass. Effect of autotransfusion of shed mediastinal blood and ultrafiltration
    Cytokine, 8 (5), 417-20
    PubMed 8726671

Publications 1995

  1. Abrahamsen TG, Mollnes TE, Vandvik B (1995)
    Intrathecal immune response in neonatal Flavobacterium meningosepticum meningitis
    Biol Neonate, 68 (2), 153-6
    PubMed 8534775
  2. Fiane AE, Videm V, Scholz T, Pedersen T, Karlsen H, Geiran O, Foerster A, Mollnes T, Aasen AO, Svennevig J (1995)
    Ex vivo model for xenotransplantation
    Transplant Proc, 27 (6), 3560-1
    PubMed 8540102
  3. Høgåsen K, Jansen JH, Mollnes TE, Hovdenes J, Harboe M (1995)
    Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiency
    J Clin Invest, 95 (3), 1054-61
    PubMed 7883953
  4. Høgåsen K, Mollnes TE, Harboe M, Götze O, Hammer HB, Oppermann M (1995)
    Terminal complement pathway activation and low lysis inhibitors in rheumatoid arthritis synovial fluid
    J Rheumatol, 22 (1), 24-8
    PubMed 7535360
  5. Kjeldsen-Kragh J, Mellbye OJ, Haugen M, Mollnes TE, Hammer HB, Sioud M, Førre O (1995)
    Changes in laboratory variables in rheumatoid arthritis patients during a trial of fasting and one-year vegetarian diet
    Scand J Rheumatol, 24 (2), 85-93
    PubMed 7747149
  6. Kuroki K, Roy S, Laerum F, Mollnes TE, Solheim BG, Videm V (1995)
    Complement activation by angiographic catheters in vitro
    J Vasc Interv Radiol, 6 (5), 819-26
    PubMed 8541691
  7. Moen O, Fosse E, Brockmeier V, Andersson C, Mollnes TE, Høgåsen K, Venge P (1995)
    Disparity in blood activation by two different heparin-coated cardiopulmonary bypass systems
    Ann Thorac Surg, 60 (5), 1317-23
    PubMed 8526620
  8. Mollnes TE, Høgåsen K, Hoaas BF, Michaelsen TE, Garred P, Harboe M (1995)
    Inhibition of complement-mediated red cell lysis by immunoglobulins is dependent on the IG isotype and its C1 binding properties
    Scand J Immunol, 41 (5), 449-56
    PubMed 7725063
  9. Mollnes TE, Riesenfeld J, Garred P, Nordström E, Høgåsen K, Fosse E, Götze O, Harboe M (1995)
    A new model for evaluation of biocompatibility: combined determination of neoepitopes in blood and on artificial surfaces demonstrates reduced complement activation by immobilization of heparin
    Artif Organs, 19 (9), 909-17
    PubMed 8687297
  10. Nielsen EW, Johansen HT, Gaudesen O, Osterud B, Olsen JO, Høgåsen K, Hack CE, Mollnes TE (1995)
    C3 is activated in hereditary angioedema, and C1/C1-inhibitor complexes rise during physical stress in untreated patients
    Scand J Immunol, 42 (6), 679-85
    PubMed 8552992
  11. Ovrum E, Mollnes TE, Fosse E, Holen EA, Tangen G, Abdelnoor M, Ringdal MA, Oystese R, Venge P (1995)
    Complement and granulocyte activation in two different types of heparinized extracorporeal circuits
    J Thorac Cardiovasc Surg, 110 (6), 1623-32
    PubMed 8523872
  12. Ovrum E, Mollnes TE, Fosse E, Holen EA, Tangen G, Ringdal MA, Videm V (1995)
    High and low heparin dose with heparin-coated cardiopulmonary bypass: activation of complement and granulocytes
    Ann Thorac Surg, 60 (6), 1755-61
    PubMed 8787476
  13. Riesenfeld J, Olsson P, Sanchez J, Mollnes TE (1995)
    Surface modification with functionally active heparin
    Med Device Technol, 6 (2), 24-31
    PubMed 10155375
  14. Røger M, Høgåsen K, Holme PA, Halstensen TS, Mollnes TE, Hovig T (1995)
    The Fluid-phase SC5b-9 Terminal Complement Complex Binds to the GPIIb/IIIa Complex of Thrombin-stimulated Human Blood Platelets Inhibiting Platelet Aggregation
    Platelets, 6 (3), 160-8
    PubMed 21043620
  15. Samdal F, Aasen AO, Mollnes TE, Høgåsen K, Amland PF (1995)
    Effect of syringe-assisted liposuction on activation of cascade systems and circulating cells when using the superwet or tumescent technique
    Ann Plast Surg, 35 (3), 242-8
    PubMed 7503516
  16. Saatvedt K, Lindberg H, Geiran OR, Michelsen S, Aasen AO, Pedersen T, Mollnes TE (1995)
    Complement activation and release of tumour necrosis factor alpha, interleukin-2, interleukin-6 and soluble tumour necrosis factor and interleukin-2 receptors during and after cardiopulmonary bypass in children
    Scand J Clin Lab Invest, 55 (1), 79-86
    PubMed 7624740

Publications 1994

  1. Busund R, Rønning G, Lindsetmo RO, Busund LT, Mollnes TE, Konopski Z, Revhaug A (1994)
    The effects of plasma and albumin infusion on organ function and sepsis markers in experimental gram-negative sepsis
    Shock, 2 (6), 402-7
    PubMed 7743369
  2. Fosse E, Moen O, Johnson E, Semb G, Brockmeier V, Mollnes TE, Fagerhol MK, Venge P (1994)
    Reduced complement and granulocyte activation with heparin-coated cardiopulmonary bypass
    Ann Thorac Surg, 58 (2), 472-7
    PubMed 8067851
  3. Høgåsen K, Mollnes TE, Brandtzaeg P (1994)
    Low levels of vitronectin and clusterin in acute meningococcal disease are closely associated with formation of the terminal-complement complex and the vitronectin-thrombin-antithrombin complex
    Infect Immun, 62 (11), 4874-80
    PubMed 7523299
  4. Mellbye OJ, Mollnes TE, Steen LS (1994)
    IgG subclass distribution and complement activation ability of autoantibodies to neutrophil cytoplasmic antigens (ANCA)
    Clin Immunol Immunopathol, 70 (1), 32-9
    PubMed 8261667
  5. Moen O, Fosse E, Bråten J, Andersson C, Fagerhol MK, Venge P, Høgåsen K, Mollnes TE (1994)
    Roller and centrifugal pumps compared in vitro with regard to haemolysis, granulocyte and complement activation
    Perfusion, 9 (2), 109-17
    PubMed 7919596
  6. Mollnes TE, Fosse E (1994)
    The complement system in trauma-related and ischemic tissue damage: a brief review
    Shock, 2 (4), 301-10
    PubMed 7757525
  7. Nielsen EW, Johansen HT, Holt J, Mollnes TE (1994)
    C1 inhibitor and diagnosis of hereditary angioedema in newborns
    Pediatr Res, 35 (2), 184-7
    PubMed 8165053
  8. Nielsen EW, Johansen HT, Straume B, Mollnes TE (1994)
    Effect of time, temperature and additives on a functional assay of C1 inhibitor
    J Immunol Methods, 173 (2), 245-51
    PubMed 8046257
  9. Nielsen EW, Stenberg PA, Einarsen E, Johansen HT, Mollnes TE (1994)
    [Angioedema associated with ACE inhibitors]
    Tidsskr Nor Laegeforen, 114 (7), 804-6
    PubMed 8009499
  10. Røger M, Høgåsen K, Mollnes TE, Hovig T (1994)
    The Membrane Glycoprotein IIb/IIIa Complex Mediates Deposition of Thrombin-stimulated Blood Platelets on Polystyrene Plastic Under Static Conditions
    Platelets, 5 (2), 96-104
    PubMed 21043610
  11. Verduin CM, Jansze M, Hol C, Mollnes TE, Verhoef J, van Dijk H (1994)
    Differences in complement activation between complement-resistant and complement-sensitive Moraxella (Branhamella) catarrhalis strains occur at the level of membrane attack complex formation
    Infect Immun, 62 (2), 589-95
    PubMed 8300216
  12. Videm V, Mollnes TE (1994)
    Human complement activation by polygeline and dextran 70
    Scand J Immunol, 39 (3), 314-20
    PubMed 7510416

Publications 1993

  1. Bengtsson A, Redl H, Paul E, Schlag G, Mollnes TE, Davies J (1993)
    Complement and leukocyte activation in septic baboons
    Circ Shock, 39 (2), 83-8
    PubMed 8490996
  2. Garred P, Fosse E, Fagerhol MK, Videm V, Mollnes TE (1993)
    Calprotectin and complement activation during major operations with or without cardiopulmonary bypass
    Ann Thorac Surg, 55 (3), 694-9
    PubMed 8452432
  3. Garred P, Lyon H, Christoffersen P, Mollnes TE, Tranum-Jensen J (1993)
    Deposition of C3, the terminal complement complex and vitronectin in primary biliary cirrhosis and primary sclerosing cholangitis
    Liver, 13 (6), 305-10
    PubMed 7507546
  4. Hetland G, Mollnes TE, Garred P (1993)
    The B chain, but not the A chain, of Ricinus communis activates human complement
    Cancer Lett, 75 (1), 59-63
    PubMed 8287382
  5. Høgåsen K, Mollnes TE, Tschopp J, Harboe M (1993)
    Quantitation of vitronectin and clusterin. Pitfalls and solutions in enzyme immunoassays for adhesive proteins
    J Immunol Methods, 160 (1), 107-15
    PubMed 7680696
  6. Jansen JH, Høgåsen K, Mollnes TE (1993)
    Extensive complement activation in hereditary porcine membranoproliferative glomerulonephritis type II (porcine dense deposit disease)
    Am J Pathol, 143 (5), 1356-65
    PubMed 8238252
  7. Jensen ET, Kharazmi A, Garred P, Kronborg G, Fomsgaard A, Mollnes TE, Høiby N (1993)
    Complement activation by Pseudomonas aeruginosa biofilms
    Microb Pathog, 15 (5), 377-88
    PubMed 8015418
  8. Mollnes TE, Nielsen EW, Høgåsen K, Mellbye OJ (1993)
    [Complement analysis tests]
    Tidsskr Nor Laegeforen, 113 (2), 211-3
    PubMed 8430403
  9. Mollnes TE, Redl H, Høgåsen K, Bengtsson A, Garred P, Speilberg L, Lea T, Oppermann M, Götze O, Schlag G (1993)
    Complement activation in septic baboons detected by neoepitope-specific assays for C3b/iC3b/C3c, C5a and the terminal C5b-9 complement complex (TCC)
    Clin Exp Immunol, 91 (2), 295-300
    PubMed 7679061
  10. Opdahl H, Mollnes TE, Naess O (1993)
    Effects of high dose E. coli lipopolysaccharide on rabbit lung function, and of subsequent addition of chemotactic granulocyte activators to their isolated, blood-perfused lungs
    Acta Anaesthesiol Scand, 37 (4), 334-42
    PubMed 8322560
  11. Røger M, Høgåsen K, Solum NO, Mollnes TE, Hovig T (1993)
    Vitronectin inhibits blood platelet aggregation
    Platelets, 4 (4), 225-9
    PubMed 21043846
  12. Svennevig JL, Geiran OR, Karlsen H, Pedersen T, Mollnes TE, Kongsgard U, Frøysaker T (1993)
    Complement activation during extracorporeal circulation. In vitro comparison of Duraflo II heparin-coated and uncoated oxygenator circuits
    J Thorac Cardiovasc Surg, 106 (3), 466-72
    PubMed 8361189

Publications 1992

  1. Halstensen TS, Mollnes TE, Garred P, Fausa O, Brandtzaeg P (1992)
    Surface epithelium related activation of complement differs in Crohn's disease and ulcerative colitis
    Gut, 33 (7), 902-8
    PubMed 1379568
  2. Hetland G, Mollnes TE, Larsen J, Garred P (1992)
    Biocompatibility of white cell filters as evaluated by complement activation
    Transfusion, 32 (6), 557-61
    PubMed 1502709
  3. Høgåsen K, Mollnes TE, Harboe M (1992)
    Heparin-binding properties of vitronectin are linked to complex formation as illustrated by in vitro polymerization and binding to the terminal complement complex
    J Biol Chem, 267 (32), 23076-82
    PubMed 1385412
  4. Røger M, Halstensen TS, Høgåsen K, Mollnes TE, Solum NO, Hovig T (1992)
    Platelets and vitronectin: immunocytochemical localization and platelet interaction with exogenously added vitronectin
    Nouv Rev Fr Hematol, 34 (1), 47-54
    PubMed 1381819
  5. Videm V, Fosse E, Mollnes TE, Garred P, Svennevig JL (1992)
    Time for new concepts about measurement of complement activation by cardiopulmonary bypass?
    Ann Thorac Surg, 54 (4), 725-31
    PubMed 1417231
  6. Videm V, Svennevig JL, Fosse E, Semb G, Osterud A, Mollnes TE (1992)
    Reduced complement activation with heparin-coated oxygenator and tubings in coronary bypass operations
    J Thorac Cardiovasc Surg, 103 (4), 806-13
    PubMed 1548925

Publications 1991

  1. Brandtzaeg P, Waage A, Mollnes TE, Oktedalen O, Kierulf P (1991)
    Severe human septic shock involves more than tumor necrosis factor
    Prog Clin Biol Res, 367, 25-42
    PubMed 1924430
  2. Hetland G, Garred P, Mollnes TE, Størvold G (1991)
    The use of flow cytometry to detect the biosynthesis of complement components
    J Immunol Methods, 140 (2), 167-71
    PubMed 2066563
  3. Hetland G, Mollnes TE, Garred P (1991)
    Activation of complement during apheresis
    Clin Exp Immunol, 84 (3), 535-8
    PubMed 1904328
  4. Mellbye OJ, Førre O, Mollnes TE, Kvarnes L (1991)
    Immunopathology of subcutaneous rheumatoid nodules
    Ann Rheum Dis, 50 (12), 909-12
    PubMed 1768157
  5. Mollnes TE, Videm V, Götze O, Harboe M, Oppermann M (1991)
    Formation of C5a during cardiopulmonary bypass: inhibition by precoating with heparin
    Ann Thorac Surg, 52 (1), 92-7
    PubMed 2069469
  6. Mollnes TE, Videm V, Riesenfeld J, Garred P, Svennevig JL, Fosse E, Hogasen K, Harboe M (1991)
    Complement activation and bioincompatibility. The terminal complement complex for evaluation and surface modification with heparin for improvement of biomaterials
    Clin Exp Immunol, 86 Suppl 1, 21-6
    PubMed 1934602
  7. Olmez U, Garred P, Mollnes TE, Harboe M, Berntzen HB, Munthe E (1991)
    C3 activation products, C3 containing immune complexes, the terminal complement complex and native C9 in patients with rheumatoid arthritis
    Scand J Rheumatol, 20 (3), 183-9
    PubMed 2068540
  8. Siemssen PA, Garred P, Olsen J, Aasen AO, Mollnes TE (1991)
    Activation of complement, kallikrein-kinin, fibrinolysis and coagulation systems by urinary catheters. Effect of time and temperature in biocompatibility studies
    Br J Urol, 67 (1), 83-7
    PubMed 1993281
  9. Videm V, Mollnes TE, Garred P, Svennevig JL (1991)
    Biocompatibility of extracorporeal circulation. In vitro comparison of heparin-coated and uncoated oxygenator circuits
    J Thorac Cardiovasc Surg, 101 (4), 654-60
    PubMed 2008104

Publications 1990

  1. Garred P, Hetland G, Mollnes TE, Stoervold G (1990)
    Synthesis of C3, C5, C6, C7, C8, and C9 by human fibroblasts
    Scand J Immunol, 32 (5), 555-60
    PubMed 2270435
  2. Garred P, Michaelsen TE, Aase A, Mollnes TE (1990)
    C3, C4, and the terminal complement complex differ from C1q by binding predominantly to the antigenic part of solid phase immune complexes
    J Immunol, 144 (1), 198-203
    PubMed 2295791
  3. Garred P, Mollnes TE, Thorsteinsson L, Erlendsson K, Steinsson K (1990)
    Increased amounts of C4-containing immune complexes and inefficient activation of C3 and the terminal complement pathway in a patient with homozygous C2 deficiency and systemic lupus erythematosus
    Scand J Immunol, 31 (1), 59-64
    PubMed 2300790
  4. Garred P, Våge DI, Mollnes TE, Harboe M (1990)
    Latex gloves as a cause of inflammation and eczema
    Lancet, 335 (8703), 1469
    PubMed 1972244
  5. Halstensen TS, Mollnes TE, Garred P, Fausa O, Brandtzaeg P (1990)
    Epithelial deposition of immunoglobulin G1 and activated complement (C3b and terminal complement complex) in ulcerative colitis
    Gastroenterology, 98 (5 Pt 1), 1264-71
    PubMed 1691118
  6. Hetland G, Garred P, Pettersen HB, Mollnes TE, Johnson E (1990)
    S protein binds to serum-treated agarose beads independently of complement activation and the formation of the terminal complement complex on the beads
    Clin Exp Immunol, 79 (3), 459-62
    PubMed 1690618
  7. Mellbye OJ, Vartdal F, Pahle J, Mollnes TE (1990)
    IgG and IgA subclass distribution of total immunoglobulin and rheumatoid factors in rheumatoid tissue plasma cells
    Scand J Rheumatol, 19 (5), 333-40
    PubMed 2218430
  8. Monaco S, Bonetti B, Ferrari S, Moretto G, Nardelli E, Tedesco F, Mollnes TE, Nobile-Orazio E, Manfredini E, Bonazzi L (1990)
    Complement-mediated demyelination in patients with IgM monoclonal gammopathy and polyneuropathy
    N Engl J Med, 322 (10), 649-52
    PubMed 1689461
  9. Pettersen HB, Johnson E, Garred P, Hetland G, Osen SS, Mollnes TE (1990)
    Quantification of non-activated (native) complement component C9 synthesized by alveolar macrophages from patients with sarcoidosis
    Scand J Immunol, 31 (5), 657-63
    PubMed 2189215
  10. Pettersen HB, Johnson E, Mollnes TE, Garred P, Hetland G, Osen SS (1990)
    Synthesis of complement by alveolar macrophages from patients with sarcoidosis
    Scand J Immunol, 31 (1), 15-23
    PubMed 1689072
  11. Roeise O, Garred P, Mollnes TE, Stadaas JO, Aasen AO (1990)
    Methylprednisolone in high doses gives different effects on the early and the late part of complement
    Eur Surg Res, 22 (1), 41-9
    PubMed 2199200
  12. Tedesco F, Radillo O, Candussi G, Nazzaro A, Mollnes TE, Pecorari D (1990)
    Immunohistochemical detection of terminal complement complex and S protein in normal and pre-eclamptic placentae
    Clin Exp Immunol, 80 (2), 236-40
    PubMed 2357851
  13. Videm V, Fosse E, Mollnes TE, Garred P, Svennevig JL (1990)
    Complement activation with bubble and membrane oxygenators in aortocoronary bypass grafting
    Ann Thorac Surg, 50 (3), 387-91
    PubMed 2205161
  14. Våge DI, Garred P, Lea T, Mollnes TE (1990)
    Elutable factors from latex-containing materials activate complement and inhibit cell proliferation. An in vitro biocompatibility study of medical devices
    Complement Inflamm, 7 (2), 63-70
    PubMed 2225794

Publications 1989

  1. Brandtzaeg P, Mollnes TE, Kierulf P (1989)
    Complement activation and endotoxin levels in systemic meningococcal disease
    J Infect Dis, 160 (1), 58-65
    PubMed 2471750
  2. Garred P, Mollnes TE, Kazatchkine MD (1989)
    Activation-dependent antigenic changes of human C3
    Complement Inflamm, 6 (3), 205-18
    PubMed 2472922
  3. Garred P, Mollnes TE, Lea T, Lachmann PJ (1989)
    Enzyme immunoassay detection of circulating immune complexes by monoclonal antibodies to C3 neoepitopes with special reference to IgG concentration and to interfering anti-immunoglobulin antibodies
    J Immunol Methods, 117 (1), 59-66
    PubMed 2464039
  4. Garred P, Olsen J, Mollnes TE, Bilde T, Glahn BE (1989)
    Biocompatibility of urinary catheters. Effect on complement activation
    Br J Urol, 63 (4), 367-71
    PubMed 2713618
  5. Halstensen TS, Mollnes TE, Brandtzaeg P (1989)
    Persistent complement activation in submucosal blood vessels of active inflammatory bowel disease: immunohistochemical evidence
    Gastroenterology, 97 (1), 10-9
    PubMed 2498144
  6. Halstensen TS, Mollnes TE, Fausa O, Brandtzaeg P (1989)
    Deposits of terminal complement complex (TCC) in muscularis mucosae and submucosal vessels in ulcerative colitis and Crohn's disease of the colon
    Gut, 30 (3), 361-6
    PubMed 2707635
  7. Hetland G, Pettersen HB, Mollnes TE, Johnson E (1989)
    S-protein is synthesized by human monocytes and macrophages in vitro
    Scand J Immunol, 29 (1), 15-21
    PubMed 2466326
  8. Høgevold HE, Aasen AO, Kierulf P, Garred P, Mollnes TE, Reikerås O (1989)
    High doses of corticosteroids in total hip replacement. Effects on components of coagulation, fibrinolytic, plasma kallikrein-kinin and complement systems
    Acta Chir Scand, 155 (4-5), 247-50
    PubMed 2678856
  9. Kongsgaard UE, Smith-Erichsen N, Geiran O, Amundsen E, Mollnes TE, Garred P (1989)
    Different activation patterns in the plasma kallikrein-kinin and complement systems during coronary bypass surgery
    Acta Anaesthesiol Scand, 33 (5), 343-7
    PubMed 2800971
  10. Mollnes TE (1989)
    [The complement system--a fascinating biological cascade. 1--physiologic aspects]
    Tidsskr Nor Laegeforen, 109 (27), 2782-8
    PubMed 2815011
  11. Mollnes TE (1989)
    Antigenic changes of complement components: relevance for the analysis of complement activation
    Complement Inflamm, 6 (3), 134-41
    PubMed 2472919
  12. Mollnes TE (1989)
    [The complement system--a fascinating biological cascade. 2--clinical aspects]
    Tidsskr Nor Laegeforen, 109 (28), 2891-6
    PubMed 2815029
  13. Mollnes TE, Abrahamsen TG, Garred P (1989)
    Alterations in the terminal complement pathway in leukopenic children with malignant diseases during episodes with evidence of infection
    Complement Inflamm, 6 (6), 460-9
    PubMed 2598645
  14. Mollnes TE, Lea T, Tschopp J (1989)
    Activation-dependent epitopes in the terminal complement pathway
    Complement Inflamm, 6 (3), 223-35
    PubMed 2472924
  15. Roeise O, Garred P, Mollnes TE, Aasen AO (1989)
    Studies on the dose dependence of endotoxin-induced in vitro activation of the complement system
    Eur Surg Res, 21 (1), 34-41
    PubMed 2714308
  16. Videm V, Fosse E, Mollnes TE, Ellingsen O, Pedersen T, Karlsen H (1989)
    Different oxygenators for cardiopulmonary bypass lead to varying degrees of human complement activation in vitro
    J Thorac Cardiovasc Surg, 97 (5), 764-70
    PubMed 2709867

Publications 1988

  1. Bhakdi S, Käflein R, Halstensen TS, Hugo F, Preissner KT, Mollnes TE (1988)
    Complement S-protein (vitronectin) is associated with cytolytic membrane-bound C5b-9 complexes
    Clin Exp Immunol, 74 (3), 459-64
    PubMed 2466593
  2. Brandtzaeg P, Kierulf P, Gaustad P, Dobloug J, Mollnes TE, Sirnes K (1988)
    Systemic meningococcal disease: a model infection to study acute endotoxinemia in man
    Prog Clin Biol Res, 272, 263-71
    PubMed 3393567
  3. Garred P, Mollnes TE, Lea T (1988)
    Quantification in enzyme-linked immunosorbent assay of a C3 neoepitope expressed on activated human complement factor C3
    Scand J Immunol, 27 (3), 329-35
    PubMed 2451274
  4. Garred P, Mollnes TE, Lea T, Fischer E (1988)
    Characterization of a monoclonal antibody MoAb bH6 reacting with a neoepitope of human C3 expressed on C3b, iC3b, and C3c
    Scand J Immunol, 27 (3), 319-27
    PubMed 2451273
  5. Halstensen TS, Mollnes TE, Brandtzaeg P (1988)
    Terminal complement complex (TCC) and S-protein (vitronectin) on follicular dendritic cells in human lymphoid tissues
    Immunology, 65 (2), 193-7
    PubMed 2461343
  6. Halstensen TS, Mollnes TE, Garred P, Brandtzaeg P (1988)
    Deposits of terminal complement complex and S-protein on follicular dendritic cells in human lymphoid tissue
    Adv Exp Med Biol, 237, 185-9
    PubMed 2978199
  7. Heideman M, Norder-Hansson B, Bengtson A, Mollnes TE (1988)
    Terminal complement complexes and anaphylatoxins in septic and ischemic patients
    Arch Surg, 123 (2), 188-92
    PubMed 3277584
  8. Hunziker T, Mollnes TE, Misiano G, Späth PJ (1988)
    Complement in chronic cutaneous lupus erythematosus
    Br J Dermatol, 118 (1), 131-3
    PubMed 3257702
  9. Mellbye OJ, Frøland SS, Lilleaasen P, Svennevig JL, Mollnes TE (1988)
    Complement activation during cardiopulmonary bypass: comparison between the use of large volumes of plasma and dextran 70
    Eur Surg Res, 20 (2), 101-9
    PubMed 2455645
  10. Mollnes TE, Garred P, Bergseth G (1988)
    Effect of time, temperature and anticoagulants on in vitro complement activation: consequences for collection and preservation of samples to be examined for complement activation
    Clin Exp Immunol, 73 (3), 484-8
    PubMed 2463123
  11. Mollnes TE, Klos A, Tschopp J (1988)
    Identification of a human C5 beta-chain epitope exposed in the native complement component but concealed in the SC5b-9 complex
    Scand J Immunol, 28 (3), 307-12
    PubMed 2461581
  12. Mollnes TE, Lachmann PJ (1988)
    Regulation of complement
    Scand J Immunol, 27 (2), 127-42
    PubMed 3277261
  13. Mollnes TE, Tambs KE, Myreng Y, Engebretsen LF (1988)
    Acute phase reactants and complement activation in patients with acute myocardial infarction
    Complement, 5 (1), 33-9
    PubMed 2448082
  14. Pettersen HB, Johnson E, Mollnes TE, Garred P (1988)
    Synthesis of soluble C3 and C9 neoepitopes by human alveolar macrophages in vitro
    Scand J Immunol, 28 (4), 431-4
    PubMed 2461585
  15. Sandberg G, Stenvinkel C, Mollnes TE (1988)
    Demonstration of C3d and the terminal complement complex on thymic large granular lymphocytes and common thymocytes after incubation with naturally thymocytotoxic serum
    Int Arch Allergy Appl Immunol, 87 (3), 239-46
    PubMed 3264545
  16. Thorlacius S, Mollnes TE, Garred P, Aarli JA, Matre R, Tönder O, Halvorsen K (1988)
    Plasma exchange in myasthenia gravis: changes in serum complement and immunoglobulins
    Acta Neurol Scand, 78 (3), 221-7
    PubMed 3227807
  17. Videm V, Fosse E, Mollnes TE, Garred P (1988)
    Complement activation by extracorporeal circulation: effects of precoating a membrane oxygenator circuit with human whole blood
    Scand J Thorac Cardiovasc Surg, 22 (3), 251-6
    PubMed 3227328

Publications 1987

  1. Fosse E, Mollnes TE, Ingvaldsen B (1987)
    Complement activation during major operations with or without cardiopulmonary bypass
    J Thorac Cardiovasc Surg, 93 (6), 860-6
    PubMed 3494886
  2. Fosse E, Mollnes TE, Osterud A, Aasen AO (1987)
    Effects of methylprednisolone on complement activation and leukocyte counts during cardiopulmonary bypass
    Scand J Thorac Cardiovasc Surg, 21 (3), 255-61
    PubMed 2964081
  3. Fosse E, Mollnes TE, Aasen AO, Trumpy JH, Stokke T (1987)
    Complement activation following multiple injuries
    Acta Chir Scand, 153 (5-6), 325-30
    PubMed 3499041
  4. Mollnes TE, Harboe M (1987)
    Immunohistochemical detection of the membrane and fluid-phase terminal complement complexes C5b-9(m) and SC5b-9. Consequences for interpretation and terminology
    Scand J Immunol, 26 (4), 381-6
    PubMed 3685888
  5. Mollnes TE, Lachmann PJ (1987)
    Activation of the third component of complement (C3) detected by a monoclonal anti-C3'g' neoantigen antibody in a one-step enzyme immunoassay
    J Immunol Methods, 101 (2), 201-7
    PubMed 2440954
  6. Mollnes TE, Tschopp J (1987)
    A unique epitope exposed in native complement component C9 and hidden in the terminal SC5b-9 complex enables selective detection and quantification of non-activated C9
    J Immunol Methods, 100 (1-2), 215-21
    PubMed 2439601
  7. Mollnes TE, Vandvik B, Lea T, Vartdal F (1987)
    Intrathecal complement activation in neurological diseases evaluated by analysis of the terminal complement complex
    J Neurol Sci, 78 (1), 17-28
    PubMed 3572448

Publications 1986

  1. Mollnes TE, Lea T, Mellbye OJ, Pahle J, Grand O, Harboe M (1986)
    Complement activation in rheumatoid arthritis evaluated by C3dg and the terminal complement complex
    Arthritis Rheum, 29 (6), 715-21
    PubMed 3718564
  2. Mollnes TE, Lea T, Rogde S, Tedesco F (1986)
    The terminal complement complex in sera deficient in the eighth component of complement (C8)
    Scand J Immunol, 24 (3), 307-12
    PubMed 3749815
  3. Mollnes TE, Ng YC, Peters DK, Lea T, Tschopp J, Harboe M (1986)
    Effect of nephritic factor on C3 and on the terminal pathway of complement in vivo and in vitro
    Clin Exp Immunol, 65 (1), 73-9
    PubMed 3641694
  4. Mollnes TE, Paus A (1986)
    Complement activation in synovial fluid and tissue from patients with juvenile rheumatoid arthritis
    Arthritis Rheum, 29 (11), 1359-64
    PubMed 3778542
  5. Tschopp J, Mollnes TE (1986)
    Antigenic crossreactivity of the alpha subunit of complement component C8 with the cysteine-rich domain shared by complement component C9 and low density lipoprotein receptor
    Proc Natl Acad Sci U S A, 83 (12), 4223-7
    PubMed 2424021

Publications 1985

  1. Mollnes TE (1985)
    Early- and late-phase activation of complement evaluated by plasma levels of C3d,g and the terminal complement complex
    Complement, 2 (2-3), 156-64
    PubMed 3878764
  2. Mollnes TE (1985)
    Quantification of the C3d split products of human complement by a sensitive enzyme-linked immunosorbent assay
    Scand J Immunol, 21 (6), 607-13
    PubMed 3895396
  3. Mollnes TE, Frøland SS, Harboe M (1985)
    Increased plasma levels of the terminal complement complex in patients with evidence of complement activation
    Complement, 2 (2-3), 175-84
    PubMed 3878765
  4. Mollnes TE, Lea T, Frøland SS, Harboe M (1985)
    Quantification of the terminal complement complex in human plasma by an enzyme-linked immunosorbent assay based on monoclonal antibodies against a neoantigen of the complex
    Scand J Immunol, 22 (2), 197-202
    PubMed 2412280
  5. Mollnes TE, Lea T, Harboe M, Tschopp J (1985)
    Monoclonal antibodies recognizing a neoantigen of poly(C9) detect the human terminal complement complex in tissue and plasma
    Scand J Immunol, 22 (2), 183-95
    PubMed 4035298

Publications 1984

  1. Mollnes TE, Lea T, Harboe M (1984)
    Detection and quantification of the terminal C5b-9 complex of human complement by a sensitive enzyme-linked immunosorbent assay
    Scand J Immunol, 20 (2), 157-66
    PubMed 6474098
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