Endosomes of fab1 mutants have an expanded size and accumulate the signalling molecules Notch, Wingless and Dpp. The signalling of these molecules is nevertheless normal. The results suggest that Fab1 controls late stages of endocytic trafficking at a point when signal termination has occurred. The mechanism by which Fab1 regulates growth remains a subject for further research.
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Autophagy, 1-382 (in press)
Should I bend or should I grow: the mechanisms of droplet-mediated autophagosome formation
Autophagy, 1-3 (in press)
Wetting regulates autophagy of phase-separated compartments and the cytosol