| Andreas M. Hoff | |
| Position: | Postdoc, PhD |
| Phone: | +47 2278 1710 |
| Email: | |
Research focus:
My research involves both wet lab work and the use of bioinformatics. I use these tools to study qualitative transcript variants and fusion genes that are involved in cancer biology and may ultimately have the potential as cancer biomarkers. More specifically:
1.Fusion transcripts involving the TCF7L2 gene in colorectal cancer and chimeric transcript overexpression in tumour versus normal.
2.Assessment of transcript structures and potential fusion genes in colorectal cancer by using a new custom targeted RNA sequencing approach.
3.Analysis of RNA sequencing data from embryonal carcinoma and embryonic stem cell lines in a testicular germ cell tumour setting.
Academic degrees:
2011: Msc in Molecular biology, University of Oslo, Norway. Transcript variation and protein expression in testicular germ cell tumours
Publications 2017
chimeraviz: a tool for visualizing chimeric RNA
Bioinformatics, 33 (18), 2954-2956
PubMed 28525538
Novel transcription-induced fusion RNAs in prostate cancer
Oncotarget, 8 (30), 49133-49143
PubMed 28467780
Publications 2015
Identification of Novel Fusion Genes in Testicular Germ Cell Tumors
Cancer Res, 76 (1), 108-16
PubMed 26659575
Novel RNA variants in colorectal cancers
Oncotarget, 6 (34), 36587-602
PubMed 26474385
Publications 2014
High frequency of fusion transcripts involving TCF7L2 in colorectal cancer: novel fusion partner and splice variants
PLoS One, 9 (3), e91264
PubMed 24608966
Publications 2013
Transforming pluripotency: an exon-level study of malignancy-specific transcripts in human embryonal carcinoma and embryonic stem cells
Stem Cells Dev, 22 (7), 1136-46
PubMed 23137282
Common fusion transcripts identified in colorectal cancer cell lines by high-throughput RNA sequencing
Transl Oncol, 6 (5), 546-53
PubMed 24151535
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