Karol Axcrona
- Associated clinical researcher; MD PhD
Publications 2024
GRIN3A: A biomarker associated with a cribriform pattern and poor prognosis in prostate cancer
Neoplasia, 55, 101023
DOI 10.1016/j.neo.2024.101023, PubMed 38944914
Outcomes of 10 years of PSA screening for prostate cancer in Norwegian men with Lynch syndrome
Prostate, 84 (10), 945-953
DOI 10.1002/pros.24711, PubMed 38629217
Prostate cancer: Molecular aspects, consequences, and opportunities of the multifocal nature
Biochim Biophys Acta Rev Cancer, 1879 (2), 189080
DOI 10.1016/j.bbcan.2024.189080, PubMed 38272101
Publications 2023
'High proliferative cribriform prostate cancer' defines a patient subgroup with an inferior prognosis
Histopathology, 83 (6), 853-869
DOI 10.1111/his.15012, PubMed 37501635
Publications 2022
A Norwegian perspective on the Swedish national guidelines on prostate cancer for non-metastatic disease
Scand J Urol, 56 (4), 274-276
DOI 10.1080/21681805.2022.2075923, PubMed 35811479
Re: Spatially Resolved Clonal Copy Number Alterations in Benign and Malignant Tissue
Eur Urol, 83 (2), 183
DOI 10.1016/j.eururo.2022.11.013, PubMed 36464529
Salmon Protein Hydrolysate Potentiates the Growth Inhibitory Effect of Bicalutamide on Human Prostate Cancer Cell Lines LNCaP and PC3 by Modulating Iron Homeostasis
Mar Drugs, 20 (4)
DOI 10.3390/md20040228, PubMed 35447901
Somatic mutations reveal complex metastatic seeding from multifocal primary prostate cancer
Int J Cancer, 152 (5), 945-951
DOI 10.1002/ijc.34226, PubMed 35880692
Collision tumors revealed by prospectively assessing subtype-defining molecular alterations in 904 individual prostate cancer foci
JCI Insight, 7 (4)
DOI 10.1172/jci.insight.155309, PubMed 35050902
In situ expression of ERG protein in the context of tumor heterogeneity identifies prostate cancer patients with inferior prognosis
Mol Oncol, 16 (15), 2810-2822
DOI 10.1002/1878-0261.13225, PubMed 35574900
Re: Fibroblast Growth Factor Receptor 1 Drives the Metastatic Progression of Prostate Cancer
Eur Urol, 81 (4), 431
DOI 10.1016/j.eururo.2021.12.031, PubMed 35031159
Expressed prognostic biomarkers for primary prostate cancer independent of multifocality and transcriptome heterogeneity
Cancer Gene Ther, 29 (8-9), 1276-1284
DOI 10.1038/s41417-022-00444-7, PubMed 35194199
Publications 2021
Prediagnostic Serum-25 Hydroxyvitamin D and Mortality Among Bladder Cancer Patients in the Janus Serum Bank Cohort: Answer to a Short Comment [Response to Letter]
Clin Epidemiol, 13, 1061-1062
DOI 10.2147/CLEP.S345565, PubMed 34803404
A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study
Lancet Oncol, 22 (11), 1618-1631
DOI 10.1016/S1470-2045(21)00522-2, PubMed 34678156
Prediagnostic Serum 25-Hydroxyvitamin D and Mortality Among Bladder Cancer Patients in the Janus Serum Bank Cohort
Clin Epidemiol, 13, 801-811
DOI 10.2147/CLEP.S319620, PubMed 34548821
Vitamin D and Vitamin D-binding protein and risk of bladder cancer: A nested case-control study in the Norwegian Janus Serum Bank Cohort
Cancer Med, 10 (12), 4107-4116
DOI 10.1002/cam4.3960, PubMed 34080787
High expression of SCHLAP1 in primary prostate cancer is an independent predictor of biochemical recurrence, despite substantial heterogeneity
Neoplasia, 23 (6), 634-641
DOI 10.1016/j.neo.2021.05.012, PubMed 34107378
Long-term first-in-man Phase I/II study of an adjuvant dendritic cell vaccine in patients with high-risk prostate cancer after radical prostatectomy
Prostate, 82 (2), 245-253
DOI 10.1002/pros.24267, PubMed 34762317
Publications 2020
A cross-sectional study of current work ability after radical prostatectomy
BMC Urol, 20 (1), 9
DOI 10.1186/s12894-020-0579-9, PubMed 32005115
The EPIC-26 domain scores after radical prostatectomy are associated with the personality trait of neuroticism
Int Urol Nephrol, 53 (4), 691-698
DOI 10.1007/s11255-020-02688-4, PubMed 33118115
Lifestyle associated factors and risk of urinary bladder cancer: A prospective cohort study from Norway
Cancer Med, 9 (12), 4420-4432
DOI 10.1002/cam4.3060, PubMed 32319230
Publications 2019
Interfocal heterogeneity challenges the clinical usefulness of molecular classification of primary prostate cancer
Sci Rep, 9 (1), 13579
DOI 10.1038/s41598-019-49964-7, PubMed 31537872
Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers
Eur Urol, 76 (6), 831-842
DOI 10.1016/j.eururo.2019.08.019, PubMed 31537406
Publications 2018
Vitamin D, obesity and leptin in relation to bladder cancer incidence and survival: prospective protocol study
BMJ Open, 8 (3), e019309
DOI 10.1136/bmjopen-2017-019309, PubMed 29602840
Multifocal Primary Prostate Cancer Exhibits High Degree of Genomic Heterogeneity
Eur Urol, 75 (3), 498-505
DOI 10.1016/j.eururo.2018.08.009, PubMed 30181068
Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition
Br J Cancer, 118 (6), e17
DOI 10.1038/bjc.2018.11, PubMed 29509747
Prostate-specific antigen velocity in a prospective prostate cancer screening study of men with genetic predisposition
Br J Cancer, 118 (2), 266-276
DOI 10.1038/bjc.2017.429, PubMed 29301143
Publications 2017
Psychometric properties of the expanded prostate cancer index composite - 26 instrument in a cohort of radical prostatectomy patients: theoretical and practical examinations
BMC Urol, 17 (1), 111
DOI 10.1186/s12894-017-0302-7, PubMed 29197360
Genetic factors influencing prostate cancer risk in Norwegian men
Prostate, 78 (3), 186-192
DOI 10.1002/pros.23453, PubMed 29181843
Correction: MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
Oncotarget, 8 (4), 7208-7213
DOI 10.18632/oncotarget.14800, PubMed 28179591
Intraductal Carcinoma of the Prostate on Diagnostic Needle Biopsy Predicts Prostate Cancer Mortality: A Population-Based Study
Prostate, 77 (8), 859-865
DOI 10.1002/pros.23326, PubMed 28240424
Ten-year Mortality in Men With Nonmetastatic Prostate Cancer in Norway
Urology, 110, 140-147
DOI 10.1016/j.urology.2017.07.048, PubMed 28823634
Publications 2016
MtDNA depleted PC3 cells exhibit Warburg effect and cancer stem cell features
Oncotarget, 7 (26), 40297-40313
DOI 10.18632/oncotarget.9610, PubMed 27248169
Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA
Clin Nutr, 36 (3), 672-679
DOI 10.1016/j.clnu.2016.06.014, PubMed 27406859
Combining lymphovascular invasion with reactive stromal grade predicts prostate cancer mortality
Prostate, 76 (12), 1088-94
DOI 10.1002/pros.23192, PubMed 27271973
Ability to Reach Orgasm in Patients With Prostate Cancer Treated With Robot-assisted Laparoscopic Prostatectomy
Urology, 92, 38-43
DOI 10.1016/j.urology.2015.11.066, PubMed 26972145
Publications 2015
The relationship between perineural invasion, tumor grade, reactive stroma and prostate cancer-specific mortality: A clinicopathologic study on a population-based cohort
Prostate, 76 (2), 207-14
DOI 10.1002/pros.23112, PubMed 26477789
The prognostic value of reactive stroma on prostate needle biopsy: a population-based study
Prostate, 75 (6), 662-71
DOI 10.1002/pros.22957, PubMed 25620661
A comparative study of erectile function and use of erectile aids in high-risk prostate cancer patients after robot-assisted laparoscopic prostatectomy
Scand J Urol, 49 (6), 433-439
DOI 10.3109/21681805.2015.1042038, PubMed 26116048
Publications 2014
Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT study
Eur Urol, 66 (3), 489-99
DOI 10.1016/j.eururo.2014.01.003, PubMed 24484606
Penile cancer in Scandinavia: Current practice and future perspectives
Scand J Urol, 50 (1), 90-2
DOI 10.3109/21681805.2014.987316, PubMed 25438987
The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer
Br J Cancer, 112 (2), 382-90
DOI 10.1038/bjc.2014.604, PubMed 25461803
Prostate-specific antigen doubling time subsequent to radical prostatectomy is a predictor of outcome following salvage external beam radiation therapy: a single-centre experience
Scand J Urol, 49 (3), 218-23
DOI 10.3109/21681805.2014.982168, PubMed 25428750
The length of a positive surgical margin is of prognostic significance in patients with clinically localized prostate cancer treated with radical prostatectomy
Urol Int, 93 (3), 289-95
DOI 10.1159/000362342, PubMed 25170745
Publications 2013
Robot-assisted radical prostatectomy of clinical high-risk patients with prostate cancer: a controlled study of operative and short-term postoperative events
Scand J Urol, 47 (6), 449-55
DOI 10.3109/21681805.2013.780257, PubMed 24328733
Dendritic and lymphocytic cell infiltration in prostate carcinoma
Histol Histopathol, 28 (12), 1621-8
DOI 10.14670/HH-28.1621, PubMed 23729368
Blocking mtDNA replication upregulates the expression of stemness-related genes in prostate cancer cell lines
Ultrastruct Pathol, 37 (4), 258-66
DOI 10.3109/01913123.2013.770112, PubMed 23634795
SHBG is an important factor in stemness induction of cells by DHT in vitro and associated with poor clinical features of prostate carcinomas
PLoS One, 8 (7), e70558 (Retracted)
DOI 10.1371/journal.pone.0070558, PubMed 23936228
Publications 2012
Androgen deprivation therapy for volume reduction, lower urinary tract symptom relief and quality of life improvement in patients with prostate cancer: degarelix vs goserelin plus bicalutamide
BJU Int, 110 (11), 1721-8
DOI 10.1111/j.1464-410X.2012.11107.x, PubMed 22500884
Routine pelvic MRI using phased-array coil for detection of extraprostatic tumour extension: accuracy and clinical significance
Eur Radiol, 23 (4), 1158-66
DOI 10.1007/s00330-012-2669-x, PubMed 23114883
Is the clinical malignant phenotype of prostate cancer a result of a highly proliferative immune-evasive B7-H3-expressing cell population?
Int J Urol, 19 (8), 749-56
DOI 10.1111/j.1442-2042.2012.03017.x, PubMed 22487487
Synergistic effect of SCF and G-CSF on stem-like properties in prostate cancer cell lines
Tumour Biol, 33 (4), 967-78
DOI 10.1007/s13277-012-0325-3, PubMed 22252524
Androgen deprivation therapy: past, present and future
BJU Int, 109 Suppl 6, 1-12
DOI 10.1111/j.1464-410X.2012.11215.x, PubMed 22672120
Does a surgeon's annual radical prostatectomy volume predict the risk of positive surgical margins and urinary incontinence at one-year follow-up? Findings from a prospective national study
Scand J Urol, 47 (2), 92-100
DOI 10.3109/00365599.2012.707684, PubMed 22860630
Bother problems in prostate cancer patients after curative treatment
Urol Oncol, 31 (7), 1067-78
DOI 10.1016/j.urolonc.2011.12.020, PubMed 22341412
Publications 2011
Robot-assisted laparoscopic prostatectomy in a 68-year-old patient with previous heart transplantation and pelvic irradiation
J Robot Surg, 6 (1), 81-3
DOI 10.1007/s11701-011-0270-y, PubMed 22408687
Transperineal prostate biopsy detects significant cancer in patients with elevated prostate-specific antigen (PSA) levels and previous negative transrectal biopsies
BJU Int, 110 (2 Pt 2), E69-75
DOI 10.1111/j.1464-410X.2011.10759.x, PubMed 22093091
Prostate cancer cell lines under hypoxia exhibit greater stem-like properties
PLoS One, 6 (12), e29170 (Retracted)
DOI 10.1371/journal.pone.0029170, PubMed 22216200
Impact of a tertiary Gleason pattern 4 or 5 on clinical failure and mortality after radical prostatectomy for clinically localised prostate cancer
BJU Int, 109 (10), 1489-94
DOI 10.1111/j.1464-410X.2011.10583.x, PubMed 21933333
Can sexual bother after radical prostatectomy be predicted preoperatively? Findings from a prospective national study of the relation between sexual function, activity and bother
BJU Int, 109 (9), 1366-74
DOI 10.1111/j.1464-410X.2011.10598.x, PubMed 21999333
Methods for prospective studies of adverse effects as applied to prostate cancer patients treated with surgery or radiotherapy without hormones
Prostate, 72 (6), 668-76
DOI 10.1002/pros.21470, PubMed 21809351
Publications 2010
Sarcomatoid squamous cell carcinoma of the penis
Acta Oncol, 49 (1), 128-30
DOI 10.3109/02841860903246565, PubMed 20100148
Targeted prostate cancer screening in men with mutations in BRCA1 and BRCA2 detects aggressive prostate cancer: preliminary analysis of the results of the IMPACT study
BJU Int, 107 (1), 28-39
DOI 10.1111/j.1464-410X.2010.09648.x, PubMed 20840664
Do perceptions of adverse events differ between patients and physicians? Findings from a randomized, controlled trial of radical treatment for prostate cancer
J Urol, 184 (2), 525-31
DOI 10.1016/j.juro.2010.04.009, PubMed 20620412
Clinicians' use of guidelines as illustrated by curative treatment of prostate cancer at a comprehensive cancer center
Acta Oncol, 50 (3), 408-14
DOI 10.3109/0284186X.2010.492236, PubMed 20586661
Publications 2009
[Incorrect about hormone treatment in prostatic cancer]
Tidsskr Nor Laegeforen, 129 (5), 429
DOI 10.4045/tidsskr.08.0649, PubMed 19247406
Initial management of prostate cancer: first year experience with the Norwegian National Prostate Cancer Registry
BJU Int, 105 (6), 805-11; discussion 811
DOI 10.1111/j.1464-410X.2009.08834.x, PubMed 19735258
Publications 2007
Photodynamic therapy with methyl aminolevulinate for atypial carcinoma in situ of the penis
Scand J Urol Nephrol, 41 (6), 507-10
DOI 10.1080/00365590701428590, PubMed 17853049
Diagnosis and treatment of primary signet-ring cell carcinoma of the prostate
Acta Oncol, 46 (8), 1195-7
DOI 10.1080/02841860701367886, PubMed 17851841
Publications 2006
Sentinel node procedure in low-stage/low-grade penile carcinomas
Scand J Urol Nephrol, 40 (3), 204-7
DOI 10.1080/00365590600589971, PubMed 16809260
Publications 2002
Uptake and intracellular transportation of a bacterial surface protein in lymphoid cells
Mol Microbiol, 44 (4), 917-34
DOI 10.1046/j.1365-2958.2002.02931.x, PubMed 12010489
Uptake and intracellular transportation of a bacterial surface protein in lymphoid cells
In Molecular microbiology, Blackwell Scientific Publications, Oxford, 44(2002)nr 4, s. 917-934
BIBSYS 031261442
Publications 2001
Et uvanlig "fall": infarkt i conus spinalis
In Vitenskapelige forhandlinger, Norsk kirurgisk forening., [Oslo], 2001, Abstrakt nr.153
BIBSYS 022015531
Regulation of transcriptional activity of the murine CD40 ligand promoter in response to signals through TCR and the costimulatory molecules CD28 and CD2
J Immunol, 166 (7), 4578-85
DOI 10.4049/jimmunol.166.7.4578, PubMed 11254715
Regulation of transcriptional activity of the murine CD40ligand promoter in response to signals through TCR and the costimulatory molecules CD28 and CD2
In Journal of immunology, The Society, Baltimore, 166(2001)7, s. 4578-85
BIBSYS 022073752
Publications 1998
Phenotypic convergence and divergence of surface immunoglobulin and CD40 signals
Scand J Immunol, 47 (3), 210-7
DOI 10.1046/j.1365-3083.1998.00295.x, PubMed 9519858
Publications 1996
Regulation of B cell growth and differentiation via CD21 and CD40
Eur J Immunol, 26 (9), 2203-7
DOI 10.1002/eji.1830260936, PubMed 8814268
Publications 1995
Multiple ligand interactions for bacterial immunoglobulin-binding proteins on human and murine cells of the hematopoetic lineage
Scand J Immunol, 42 (3), 359-67
DOI 10.1111/j.1365-3083.1995.tb03668.x, PubMed 7660068