An international research team, led by Danielle Posthuma from Vrije Universiteit Amsterdam and Ole Andreassen from from The Norwegian Centre for Mental Disorders Research (NORMENT) at the Division for Mental Health and Addiction Oslo University Hospital and the University of Oslo, has conducted large-scale genetic research into the different backgrounds of the risk of Alzheimer's disease.
The results, which have been published in Nature Genetics, pointed towards the involvement of genes specifically expressed in microglia, indicating that these types of cells, which are known to be involved in immune system, are important in the pathogenesis of AD.
Complete article from the news section of Vrije Universiteit Amsterdam:
New causes for Alzheimer's discovered
The Nature Genetics publication:
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.
Wightman DP, Jansen IE [...] Andreassen OA, Posthuma D.
Nat Genet. 2021 Sep;53(9):1276-1282. doi: 10.1038/s41588-021-00921-z. Epub 2021 Sep 7.