Visting address: Kirkeveien 166 Bygg 49 0450 Oslo
Postal adress: Oslo Universitetssykehus Postboks 4956 Nydalen 0424 Oslo
Publications 2023
A Breast Cancer Polygenic Risk Score Is Feasible for Risk Stratification in the Norwegian Population
Cancers (Basel), 15 (16)
DOI 10.3390/cancers15164124, PubMed 37627152
Longitudinal transcriptomic analysis of human cortical spheroids identifies axonal dysregulation in the prenatal brain as a mediator of genetic risk for schizophrenia
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2023.08.017, PubMed 37661009
New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications
World Psychiatry, 22 (1), 4-24
DOI 10.1002/wps.21034, PubMed 36640404
Association between cannabis use and symptom dimensions in schizophrenia spectrum disorders: an individual participant data meta-analysis on 3053 individuals
EClinicalMedicine, 64, 102199
DOI 10.1016/j.eclinm.2023.102199, PubMed 37731936
Developmental manifestations of polygenic risk for bipolar disorder from infancy to middle childhood
Transl Psychiatry, 13 (1), 222
DOI 10.1038/s41398-023-02522-2, PubMed 37353490
Genome-wide analysis of anorexia nervosa and major psychiatric disorders and related traits reveals genetic overlap and identifies novel risk loci for anorexia nervosa
Transl Psychiatry, 13 (1), 291
DOI 10.1038/s41398-023-02585-1, PubMed 37658054
Altered Sex Differences in Hippocampal Subfield Volumes in Schizophrenia
Schizophr Bull (in press)
DOI 10.1093/schbul/sbad091, PubMed 37354490
Exploratory study of ultraviolet B (UVB) radiation and age of onset of bipolar disorder
Int J Bipolar Disord, 11 (1), 22
DOI 10.1186/s40345-023-00303-w, PubMed 37347392
Puberty differentially predicts brain maturation in male and female youth: A longitudinal ABCD Study
Dev Cogn Neurosci, 61, 101261
DOI 10.1016/j.dcn.2023.101261, PubMed 37295068
Distinct biological signature and modifiable risk factors underly the comorbidity between major depressive disorder and cardiovascular disease
medRxiv
DOI 10.1101/2023.09.01.23294931, PubMed 37693619
Psychometric Properties and Diagnostic Associations of the Short-Form Community Assessment of Psychic Experiences in a Population-Based Sample of 29 021 Adult Men
Schizophr Bull, 49 (5), 1229-1238
DOI 10.1093/schbul/sbad074, PubMed 37262330
No signs of neurodegenerative effects in 15q11.2 BP1-BP2 copy number variant carriers in the UK Biobank
Transl Psychiatry, 13 (1), 61
DOI 10.1038/s41398-023-02358-w, PubMed 36807331
Beyond the Global Brain Differences: Intra-individual Variability Differences in 1q21.1 Distal and 15q11.2 BP1-BP2 Deletion Carriers
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2023.08.018, PubMed 37661008
Distributed Genetic Effects of the Corpus Callosum Subregions Suggest Links to Neuropsychiatric Disorders and Related Traits
Acta Neuropsychiatr, 1-21 (in press)
DOI 10.1017/neu.2023.32, PubMed 37612147
The relationship between cannabis use, schizophrenia, and bipolar disorder: a genetically informed study
Lancet Psychiatry, 10 (6), 441-451
DOI 10.1016/S2215-0366(23)00143-8, PubMed 37208114
Author Correction: Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Nat Commun, 14 (1), 716
DOI 10.1038/s41467-023-36192-x, PubMed 36759603
Bounding the average causal effect in Mendelian randomisation studies with multiple proposed instruments: An application to prenatal alcohol exposure and attention deficit hyperactivity disorder
Paediatr Perinat Epidemiol, 37 (4), 326-337
DOI 10.1111/ppe.12951, PubMed 36722651
Genetic Associations Between Modifiable Risk Factors and Alzheimer Disease
JAMA Netw Open, 6 (5), e2313734
DOI 10.1001/jamanetworkopen.2023.13734, PubMed 37195665
Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system
Neurobiol Dis, 183, 106174
DOI 10.1016/j.nbd.2023.106174, PubMed 37286172
Cross-trait genome-wide association analysis of C-reactive protein level and psychiatric disorders
Psychoneuroendocrinology, 157, 106368 (in press)
DOI 10.1016/j.psyneuen.2023.106368, PubMed 37659117
Multivariate genetic analysis of personality and cognitive traits reveals abundant pleiotropy
Nat Hum Behav, 7 (9), 1584-1600
DOI 10.1038/s41562-023-01630-9, PubMed 37365406
Impulsivity across severe mental disorders: a cross-sectional study of immune markers and psychopharmacotherapy
BMC Psychiatry, 23 (1), 659
DOI 10.1186/s12888-023-05154-4, PubMed 37674162
Genome-wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
Addict Biol, 28 (6), e13282
DOI 10.1111/adb.13282, PubMed 37252880
Systemic immune profile in Prader-Willi syndrome: elevated matrix metalloproteinase and myeloperoxidase and reduced macrophage inhibitory factor
Orphanet J Rare Dis, 18 (1), 185
DOI 10.1186/s13023-023-02730-5, PubMed 37430349
Bidirectional genetic overlap between autism spectrum disorder and cognitive traits
Transl Psychiatry, 13 (1), 295
DOI 10.1038/s41398-023-02563-7, PubMed 37709755
Normative modeling of brain morphometry in Clinical High-Risk for Psychosis
bioRxiv
DOI 10.1101/2023.01.17.523348, PubMed 36711551
Etiologic Studies of Premenstrual Disorders Require Prospective Confirmation of Affective Cyclicity-Reply
JAMA Psychiatry (in press)
DOI 10.1001/jamapsychiatry.2023.3290, PubMed 37703043
Genome-wide Association Analysis of Schizophrenia and Vitamin D Levels Shows Shared Genetic Architecture and Identifies Novel Risk Loci
Schizophr Bull (in press)
DOI 10.1093/schbul/sbad063, PubMed 37163672
Associations Between Symptoms of Premenstrual Disorders and Polygenic Liability for Major Psychiatric Disorders
JAMA Psychiatry, 80 (7), 738-742
DOI 10.1001/jamapsychiatry.2023.1137, PubMed 37163253
Do environmental effects indexed by parental genetic variation influence common psychiatric symptoms in childhood?
Transl Psychiatry, 13 (1), 94
DOI 10.1038/s41398-023-02348-y, PubMed 36934099
Elevated Systemic Levels of Markers Reflecting Intestinal Barrier Dysfunction and Inflammasome Activation Are Correlated in Severe Mental Illness
Schizophr Bull, 49 (3), 635-645
DOI 10.1093/schbul/sbac191, PubMed 36462169
Precision medicine in complex diseases-Molecular subgrouping for improved prediction and treatment stratification
J Intern Med, 294 (4), 378-396
DOI 10.1111/joim.13640, PubMed 37093654
Leveraging genetic overlap between irritability and psychiatric disorders to identify genetic variants of major psychiatric disorders
Exp Mol Med, 55 (6), 1193-1202
DOI 10.1038/s12276-023-01005-0, PubMed 37258574
Identification of novel genomic risk loci shared between common epilepsies and psychiatric disorders
Brain, 146 (8), 3392-3403
DOI 10.1093/brain/awad038, PubMed 36757824
Rare CNVs and phenome-wide profiling highlight brain structural divergence and phenotypical convergence
Nat Hum Behav, 7 (6), 1001-1017
DOI 10.1038/s41562-023-01541-9, PubMed 36864136
Using rare genetic mutations to revisit structural brain asymmetry
bioRxiv
DOI 10.1101/2023.04.17.537199, PubMed 37131672
Brain-wide associations between white matter and age highlight the role of fornix microstructure in brain ageing
Hum Brain Mapp, 44 (10), 4101-4119
DOI 10.1002/hbm.26333, PubMed 37195079
Bio-psycho-social factors' associations with brain age: a large-scale UK Biobank diffusion study of 35,749 participants
Front Psychol, 14, 1117732
DOI 10.3389/fpsyg.2023.1117732, PubMed 37359862
Considerations on brain age predictions from repeatedly sampled data across time
Brain Behav, e3219 (in press)
DOI 10.1002/brb3.3219, PubMed 37587620
Subcortical Brain Alterations in Carriers of Genomic Copy Number Variants
Am J Psychiatry, 180 (9), 685-698
DOI 10.1176/appi.ajp.20220304, PubMed 37434504
Subcortical brain alterations in carriers of genomic copy number variants
medRxiv
DOI 10.1101/2023.02.14.23285913, PubMed 36865328
Combining antidepressants and attention bias modification in primary health care (DEPTREAT): Protocol for a pragmatic randomized controlled trial
Contemp Clin Trials, 133, 107326 (in press)
DOI 10.1016/j.cct.2023.107326, PubMed 37652355
Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by HLA-DRB1*04 subtypes
Proc Natl Acad Sci U S A, 120 (36), e2302720120
DOI 10.1073/pnas.2302720120, PubMed 37643212
Genetic architecture of brain age and its causal relations with brain and mental disorders
Mol Psychiatry (in press)
DOI 10.1038/s41380-023-02087-y, PubMed 37165155
Visual processing deficits in patients with schizophrenia spectrum and bipolar disorders and associations with psychotic symptoms, and intellectual abilities
Heliyon, 9 (2), e13354
DOI 10.1016/j.heliyon.2023.e13354, PubMed 36825178
Mega-analysis of association between obesity and cortical morphology in bipolar disorders: ENIGMA study in 2832 participants
Psychol Med, 1-11 (in press)
DOI 10.1017/S0033291723000223, PubMed 36846964
Cognitive performance at first episode of psychosis and the relationship with future treatment resistance: Evidence from an international prospective cohort study
Schizophr Res, 255, 173-181
DOI 10.1016/j.schres.2023.03.020, PubMed 37001392
Telomere length and verbal learning in bipolar disorders
J Affect Disord, 339, 555-560
DOI 10.1016/j.jad.2023.07.087, PubMed 37459977
The Genetic Architecture of Amygdala Nuclei
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2023.06.022, PubMed 37391117
Brain-based gene expression of putative risk genes for anorexia nervosa
Mol Psychiatry (in press)
DOI 10.1038/s41380-023-02110-2, PubMed 37221367
Genetic mechanisms for impaired synaptic plasticity in schizophrenia revealed by computational modelling
bioRxiv
DOI 10.1101/2023.06.14.544920, PubMed 37398070
Thalamic nuclei volumes in schizophrenia and bipolar spectrum disorders - Associations with diagnosis and clinical characteristics
Schizophr Res, 256, 26-35
DOI 10.1016/j.schres.2023.04.008, PubMed 37126979
Multi-Site Statistical Mapping of Along-Tract Microstructural Abnormalities in Bipolar Disorder with Diffusion MRI Tractometry
bioRxiv
DOI 10.1101/2023.08.17.553762, PubMed 37662230
Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders
medRxiv
DOI 10.1101/2023.08.31.23294915, PubMed 37693460
Erratum to "Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents" [Dev. Cogn. Neurosci. 56C (2022) 101132]
Dev Cogn Neurosci, 61, 101225
DOI 10.1016/j.dcn.2023.101225, PubMed 36870926
Pleiotropy with sex-specific traits reveals genetic aspects of sex differences in Parkinson's disease
Brain (in press)
DOI 10.1093/brain/awad297, PubMed 37671566
Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
Psychiatry Res, 325, 115217
DOI 10.1016/j.psychres.2023.115217, PubMed 37146461
Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3453
DOI 10.1038/s41467-023-38951-2, PubMed 37301908
Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality
Nat Commun, 14 (1), 3923
DOI 10.1038/s41467-023-39492-4, PubMed 37400429
Transcriptional and functional effects of lithium in bipolar disorder iPSC-derived cortical spheroids
Mol Psychiatry (in press)
DOI 10.1038/s41380-023-01944-0, PubMed 36653674
Genetic liability to schizophrenia and cardiac structure and function
Lancet Psychiatry, 10 (2), 72-73
DOI 10.1016/S2215-0366(23)00009-3, PubMed 36632819
Genetic Overlap Between Global Cortical Brain Structure, C-Reactive Protein, and White Blood Cell Counts
Biol Psychiatry (in press)
DOI 10.1016/j.biopsych.2023.06.008, PubMed 37348803
Epidemiological overview of major depressive disorder in Scandinavia using nationwide registers
Lancet Reg Health Eur, 29, 100621
DOI 10.1016/j.lanepe.2023.100621, PubMed 37265784
Mismatch negativity in schizophrenia spectrum and bipolar disorders: Group and sex differences and associations with symptom severity
Schizophr Res, 261, 80-93 (in press)
DOI 10.1016/j.schres.2023.09.012, PubMed 37716205
Improved multimodal prediction of progression from MCI to Alzheimer's disease combining genetics with quantitative brain MRI and cognitive measures
Alzheimers Dement (in press)
DOI 10.1002/alz.13112, PubMed 37132098
Polygenic risk for schizophrenia and bipolar disorder in relation to cardiovascular biomarkers
Eur Arch Psychiatry Clin Neurosci (in press)
DOI 10.1007/s00406-023-01591-0, PubMed 37145175
Shared genetic architecture between mental health and the brain functional connectome in the UK Biobank
BMC Psychiatry, 23 (1), 461
DOI 10.1186/s12888-023-04905-7, PubMed 37353766
Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium
Proc Natl Acad Sci U S A, 120 (14), e2213880120
DOI 10.1073/pnas.2213880120, PubMed 36976765
Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience: A Review
JAMA Psychiatry (in press)
DOI 10.1001/jamapsychiatry.2023.2996, PubMed 37610741
Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders
Nat Neurosci, 26 (9), 1613-1629
DOI 10.1038/s41593-023-01404-6, PubMed 37580620
Psychiatric disorders and subsequent risk of cardiovascular disease: a longitudinal matched cohort study across three countries
EClinicalMedicine, 61, 102063
DOI 10.1016/j.eclinm.2023.102063, PubMed 37425374
Patterns of pharmacotherapy for bipolar disorder: A GBC survey
Bipolar Disord (in press)
DOI 10.1111/bdi.13366, PubMed 37463846
Relationship between function and structure in the visual cortex in healthy individuals and in patients with severe mental disorders
Psychiatry Res Neuroimaging, 332, 111633
DOI 10.1016/j.pscychresns.2023.111633, PubMed 37028226
Genome-wide analyses reveal widespread genetic overlap between neurological and psychiatric disorders and a convergence of biological associations related to the brain
medRxiv
DOI 10.1101/2023.07.21.23292993, PubMed 37503175
Heritability Estimation of Cognitive Phenotypes in the ABCD Study® Using Mixed Models
Behav Genet, 53 (3), 169-188
DOI 10.1007/s10519-023-10141-2, PubMed 37024669
Genetic effects on the timing of parturition and links to fetal birth weight
Nat Genet, 55 (4), 559-567
DOI 10.1038/s41588-023-01343-9, PubMed 37012456
Author Correction: Genetic effects on the timing of parturition and links to fetal birth weight
Nat Genet, 55 (7), 1250
DOI 10.1038/s41588-023-01412-z, PubMed 37165137
Shared Genetic Loci Between Schizophrenia and White Blood Cell Counts Suggest Genetically Determined Systemic Immune Abnormalities
Schizophr Bull, 49 (5), 1345-1354
DOI 10.1093/schbul/sbad082, PubMed 37319439
The effect of maternal BMI, smoking and alcohol on congenital heart diseases: a Mendelian randomisation study
BMC Med, 21 (1), 35
DOI 10.1186/s12916-023-02731-y, PubMed 36721200
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis
Genome Med, 15 (1), 60
DOI 10.1186/s13073-023-01212-4, PubMed 37528461
Identification of Novel Genomic Loci for Anxiety and Extensive Genetic Overlap with Psychiatric Disorders
medRxiv
DOI 10.1101/2023.09.01.23294920, PubMed 37693403
Risk of recurrent cardiovascular events in coronary artery disease patients with Type D personality
Front Psychol, 14, 1119146
DOI 10.3389/fpsyg.2023.1119146, PubMed 37057178
Patients with schizophrenia and bipolar disorder display a similar global gene expression signature in whole blood that reflects elevated proportion of immature neutrophil cells with association to lipid changes
Transl Psychiatry, 13 (1), 147
DOI 10.1038/s41398-023-02442-1, PubMed 37147304
Differences in white blood cell proportions between schizophrenia cases and controls are influenced by medication and variations in time of day
Transl Psychiatry, 13 (1), 211
DOI 10.1038/s41398-023-02507-1, PubMed 37330513
Delineating disorder-general and disorder-specific dimensions of psychopathology from functional brain networks in a developmental clinical sample
Dev Cogn Neurosci, 62, 101271
DOI 10.1016/j.dcn.2023.101271, PubMed 37348146
Shared pattern of impaired social communication and cognitive ability in the youth brain across diagnostic boundaries
Dev Cogn Neurosci, 60, 101219
DOI 10.1016/j.dcn.2023.101219, PubMed 36812678
TMEM161B modulates radial glial scaffolding in neocortical development
Proc Natl Acad Sci U S A, 120 (4), e2209983120
DOI 10.1073/pnas.2209983120, PubMed 36669109
Pregnancy-Associated Bleeding and Genetics: Five Sequence Variants in the Myometrium and Progesterone Signaling Pathway are associated with postpartum hemorrhage
medRxiv
DOI 10.1101/2023.08.10.23293932, PubMed 37645979
Reaction Time Variability in Children Is Specifically Associated With Attention Problems and Regional White Matter Microstructure
Biol Psychiatry Cogn Neurosci Neuroimaging, 8 (8), 832-840
DOI 10.1016/j.bpsc.2023.03.010, PubMed 37003411
Genome-wide association study in 404,302 individuals identifies 7 significant loci for reaction time variability
medRxiv
DOI 10.1101/2023.04.03.23288056, PubMed 37066411
Associations between health behaviours, fertility and reproductive outcomes: triangulation of evidence in the Norwegian Mother, Father and Child Cohort Study (MoBa)
BMC Med, 21 (1), 125
DOI 10.1186/s12916-023-02831-9, PubMed 37013617
Baseline long-term potentiation-like cortical plasticity is associated with longitudinal cortical thinning in healthy adults and in adults with bipolar disorder type II
Eur J Neurosci, 58 (3), 2824-2837
DOI 10.1111/ejn.16038, PubMed 37163975
Expression of ANK3 moderates the association between childhood trauma and affective traits in severe mental disorders
Sci Rep, 13 (1), 13845
DOI 10.1038/s41598-023-40310-6, PubMed 37620394
Publications 2022
Derivation and Molecular Characterization of a Morphological Subpopulation of Human iPSC Astrocytes Reveal a Potential Role in Schizophrenia and Clozapine Response
Schizophr Bull, 48 (1), 190-198
DOI 10.1093/schbul/sbab092, PubMed 34357384
Lifetime and point prevalence of psychotic symptoms in adults with bipolar disorders: a systematic review and meta-analysis
Psychol Med, 52 (13), 2413-2425
DOI 10.1017/S003329172200201X, PubMed 36016504
Herpes simplex virus 1 infection on grey matter and general intelligence in severe mental illness
Transl Psychiatry, 12 (1), 276
DOI 10.1038/s41398-022-02044-3, PubMed 35821107
Cytomegalovirus Infection Associated with Smaller Total Cortical Surface Area in Schizophrenia Spectrum Disorders
Schizophr Bull, 48 (5), 1164-1173
DOI 10.1093/schbul/sbac036, PubMed 35388401
Dissecting the shared genetic basis of migraine and mental disorders using novel statistical tools
Brain, 145 (1), 142-153
DOI 10.1093/brain/awab267, PubMed 34273149
Distributed genetic architecture across the hippocampal formation implies common neuropathology across brain disorders
Nat Commun, 13 (1), 3436
DOI 10.1038/s41467-022-31086-w, PubMed 35705537
Childhood temperamental, emotional, and behavioral characteristics associated with mood and anxiety disorders in adolescence: A prospective study
Acta Psychiatr Scand, 147 (2), 217-228
DOI 10.1111/acps.13522, PubMed 36398468
Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis
Transl Psychiatry, 12 (1), 297
DOI 10.1038/s41398-022-02057-y, PubMed 35882855
In vivo white matter microstructure in adolescents with early-onset psychosis: a multi-site mega-analysis
Mol Psychiatry, 28 (3), 1159-1169
DOI 10.1038/s41380-022-01901-3, PubMed 36510004
Association between polarity of first episode and solar insolation in bipolar I disorder
J Psychosom Res, 160, 110982
DOI 10.1016/j.jpsychores.2022.110982, PubMed 35932492
Adipose tissue distribution from body MRI is associated with cross-sectional and longitudinal brain age in adults
Neuroimage Clin, 33, 102949
DOI 10.1016/j.nicl.2022.102949, PubMed 35114636
Psychopathy subdomains in violent offenders with and without a psychotic disorder
Nord J Psychiatry, 77 (4), 393-402
DOI 10.1080/08039488.2022.2128869, PubMed 36260740
New insights into the genetic etiology of Alzheimer's disease and related dementias
Nat Genet, 54 (4), 412-436
DOI 10.1038/s41588-022-01024-z, PubMed 35379992
Developing "MinDag" - an app to capture symptom variation and illness mechanisms in bipolar disorder
Front Med Technol, 4, 910533
DOI 10.3389/fmedt.2022.910533, PubMed 35935144
Alcohol use and alcohol use disorder differ in their genetic relationships with PTSD: A genomic structural equation modelling approach
Drug Alcohol Depend, 234, 109430
DOI 10.1016/j.drugalcdep.2022.109430, PubMed 35367939
Genetic variants associated with longitudinal changes in brain structure across the lifespan
Nat Neurosci, 25 (4), 421-432
DOI 10.1038/s41593-022-01042-4, PubMed 35383335
Predictors of functional impairment in bipolar disorder: Results from 13 cohorts from seven countries by the global bipolar cohort collaborative
Bipolar Disord, 24 (7), 709-719
DOI 10.1111/bdi.13208, PubMed 35322518
Cytomegalovirus infection associated with lower IQ in adolescent patients with schizophrenia spectrum disorders: A preliminary report
J Psychiatr Res, 151, 571-574
DOI 10.1016/j.jpsychires.2022.05.036, PubMed 35636034
A population-wide gene-environment interaction study on how genes, schools, and residential areas shape achievement
NPJ Sci Learn, 7 (1), 29
DOI 10.1038/s41539-022-00145-8, PubMed 36302785
How interactions between ADHD and schools affect educational achievement: a family-based genetically sensitive study
J Child Psychol Psychiatry, 63 (10), 1174-1185
DOI 10.1111/jcpp.13656, PubMed 35789088
Genome-Transcriptome-Functional Connectivity-Cognition Link Differentiates Schizophrenia From Bipolar Disorder
Schizophr Bull, 48 (6), 1306-1317
DOI 10.1093/schbul/sbac088, PubMed 35988022
Shared genetic architecture between schizophrenia and subcortical brain volumes implicates early neurodevelopmental processes and brain development in childhood
Mol Psychiatry, 27 (12), 5167-5176
DOI 10.1038/s41380-022-01751-z, PubMed 36100668
Cross disorder comparisons of brain structure in schizophrenia, bipolar disorder, major depressive disorder, and 22q11.2 deletion syndrome: A review of ENIGMA findings
Psychiatry Clin Neurosci, 76 (5), 140-161
DOI 10.1111/pcn.13337, PubMed 35119167
Associations Between Depression and Cardiometabolic Health: A 27-Year Longitudinal Study - Corrigendum
Psychol Med, 52 (14), 3018
DOI 10.1017/S0033291722003105, PubMed 36177891
On the importance of parenting in externalizing disorders: an evaluation of indirect genetic effects in families
J Child Psychol Psychiatry, 63 (10), 1186-1195
DOI 10.1111/jcpp.13654, PubMed 35778910
Composite immune marker scores associated with severe mental disorders and illness course
Brain Behav Immun Health, 24, 100483
DOI 10.1016/j.bbih.2022.100483, PubMed 35856063
Plasma Levels of the Cytokines B Cell-Activating Factor (BAFF) and A Proliferation-Inducing Ligand (APRIL) in Schizophrenia, Bipolar, and Major Depressive Disorder: A Cross Sectional, Multisite Study
Schizophr Bull, 48 (1), 37-46
DOI 10.1093/schbul/sbab106, PubMed 34499169
Multivariate genome-wide association study on tissue-sensitive diffusion metrics highlights pathways that shape the human brain
Nat Commun, 13 (1), 2423
DOI 10.1038/s41467-022-30110-3, PubMed 35505052
Associations between brain imaging and polygenic scores of mental health and educational attainment in children aged 9-11
Neuroimage, 263, 119611
DOI 10.1016/j.neuroimage.2022.119611, PubMed 36070838
Ethical considerations for precision psychiatry: A roadmap for research and clinical practice
Eur Neuropsychopharmacol, 63, 17-34
DOI 10.1016/j.euroneuro.2022.08.001, PubMed 36041245
Lifetime Cannabis Use Is Not Associated With Negative Beliefs About Medication in Patients With First Treatment Psychosis
Front Psychiatry, 13, 824051
DOI 10.3389/fpsyt.2022.824051, PubMed 35422717
Local molecular and global connectomic contributions to cross-disorder cortical abnormalities
Nat Commun, 13 (1), 4682
DOI 10.1038/s41467-022-32420-y, PubMed 35948562
Associations Between Pregnancy-Related Predisposing Factors for Offspring Neurodevelopmental Conditions and Parental Genetic Liability to Attention-Deficit/Hyperactivity Disorder, Autism, and Schizophrenia: The Norwegian Mother, Father and Child Cohort Study (MoBa)
JAMA Psychiatry, 79 (8), 799-810
DOI 10.1001/jamapsychiatry.2022.1728, PubMed 35793100
Characterization of the genetic architecture of infant and early childhood body mass index
Nat Metab, 4 (3), 344-358
DOI 10.1038/s42255-022-00549-1, PubMed 35315439
Smoking and infertility: multivariable regression and Mendelian randomization analyses in the Norwegian Mother, Father and Child Cohort Study
Fertil Steril, 118 (1), 180-190
DOI 10.1016/j.fertnstert.2022.04.001, PubMed 35562204
Coordinated cortical thickness alterations across six neurodevelopmental and psychiatric disorders
Nat Commun, 13 (1), 6851
DOI 10.1038/s41467-022-34367-6, PubMed 36369423
Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation
Am J Psychiatry, 179 (11), 833-843
DOI 10.1176/appi.ajp.21101051, PubMed 36069018
The shared genetic basis of mood instability and psychiatric disorders: A cross-trait genome-wide association analysis
Am J Med Genet B Neuropsychiatr Genet, 189 (6), 207-218
DOI 10.1002/ajmg.b.32907, PubMed 35841185
Interleukin-18 signaling system links to agitation in severe mental disorders
Psychoneuroendocrinology, 140, 105721
DOI 10.1016/j.psyneuen.2022.105721, PubMed 35301151
Polygenic resilience scores capture protective genetic effects for Alzheimer's disease
Transl Psychiatry, 12 (1), 296
DOI 10.1038/s41398-022-02055-0, PubMed 35879306
Within-sibship genome-wide association analyses decrease bias in estimates of direct genetic effects
Nat Genet, 54 (5), 581-592
DOI 10.1038/s41588-022-01062-7, PubMed 35534559
Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study
Elife, 11
DOI 10.7554/eLife.74320, PubMed 36537070
Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score
Prostate Cancer Prostatic Dis, 25 (4), 755-761
DOI 10.1038/s41391-022-00497-7, PubMed 35152271
Preventive Medication Patterns in Bipolar Disorder and Their Relationship With Comorbid Substance Use Disorders in a Cross-National Observational Study
Front Psychiatry, 13, 813256
DOI 10.3389/fpsyt.2022.813256, PubMed 35592382
Genetic overlap between mood instability and alcohol-related phenotypes suggests shared biological underpinnings
Neuropsychopharmacology, 47 (11), 1883-1891
DOI 10.1038/s41386-022-01401-6, PubMed 35953530
Limited evidence for a moderating effect of HIV status on brain age in heavy episodic drinkers
J Neurovirol, 28 (3), 383-391
DOI 10.1007/s13365-022-01072-5, PubMed 35355213
Birth order differences in education originate in postnatal environments
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Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms
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Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers
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Correction to: Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1198
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Sex differences in antipsychotic-related triglyceride levels are associated with metabolic hormone differences in patients with severe mental disorders
Schizophr Res, 243, 55-63
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Sex-specific associations between metabolic hormones, severe mental disorders and antipsychotic treatment
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Genomic Stratification of Clozapine Prescription Patterns Using Schizophrenia Polygenic Scores
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Closing the life-cycle of normative modeling using federated hierarchical Bayesian regression
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Mapping Normative Trajectories of Cognitive Function and Its Relation to Psychopathology Symptoms and Genetic Risk in Youth
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Study protocol for "MDMA-assisted therapy as a treatment for major depressive disorder: A proof of principle study"
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Metabolite Profiling of Clozapine in Patients Switching Versus Maintaining Treatment: A Retrospective Pilot Study
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Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease
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Impact of NFIB and CYP1A variants on clozapine serum concentration-A retrospective naturalistic cohort study on 526 patients with known smoking habits
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Deep neural networks learn general and clinically relevant representations of the ageing brain
Neuroimage, 256, 119210
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Generalization of cortical MOSTest genome-wide associations within and across samples
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Functional connectivity directionality between large-scale resting-state networks across typical and non-typical trajectories in children and adolescence
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An epigenetic association analysis of childhood trauma in psychosis reveals possible overlap with methylation changes associated with PTSD
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Acute COVID-19 severity and mental health morbidity trajectories in patient populations of six nations: an observational study
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Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases
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Strategies and foundations for scientific discovery in longitudinal studies of bipolar disorder
Bipolar Disord, 24 (5), 499-508
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Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations
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Negative Symptom Domains Are Associated With Verbal Learning in Adolescents With Early Onset Psychosis
Front Psychiatry, 12, 825681
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A comparison of intracranial volume estimation methods and their cross-sectional and longitudinal associations with age
Hum Brain Mapp, 43 (15), 4620-4639
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Parental socioeconomic status is linked to cortical microstructure and language abilities in children and adolescents
Dev Cogn Neurosci, 56, 101132
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Phenotype-informed polygenic risk scores are associated with worse outcome in individuals at risk of Alzheimer's disease
Alzheimers Dement (Amst), 14 (1), e12350
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Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia
JAMA Psychiatry, 79 (3), 260-269
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Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology
Commun Biol, 5 (1), 1024
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Virtual Ontogeny of Cortical Growth Preceding Mental Illness
Biol Psychiatry, 92 (4), 299-313
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Computational Modeling of the n-Back Task in the ABCD Study: Associations of Drift Diffusion Model Parameters to Polygenic Scores of Mental Disorders and Cardiometabolic Diseases
Biol Psychiatry Cogn Neurosci Neuroimaging, 8 (3), 290-299
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Genetic nurture versus genetic transmission of risk for ADHD traits in the Norwegian Mother, Father and Child Cohort Study
Mol Psychiatry, 28 (4), 1731-1738
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The co-occurrence of motor and language impairments in children evaluated for autism spectrum disorder. An explorative study from Norway
Res Dev Disabil, 127, 104256
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Quality of clinical management of cardiometabolic risk factors in patients with severe mental illness in a specialist mental health care setting
Nord J Psychiatry, 76 (8), 602-609
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Oxytocin receptor expression patterns in the human brain across development
Neuropsychopharmacology, 47 (8), 1550-1560
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Clinical and cortical similarities identified between bipolar disorder I and schizophrenia: A multivariate approach
Front Hum Neurosci, 16, 1001692
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Cardiovascular disease risk in people with severe mental disorders: an update and call for action
Curr Opin Psychiatry, 35 (4), 277-284
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Multiomics analysis of rheumatoid arthritis yields sequence variants that have large effects on risk of the seropositive subset
Ann Rheum Dis, 81 (8), 1085-1095
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Theory of mind in schizophrenia: a comparison of subgroups with low and high IQ
Nord J Psychiatry, 77 (4), 329-335
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Associations between abdominal adipose tissue, reproductive span, and brain characteristics in post-menopausal women
Neuroimage Clin, 36, 103239
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Systemic Cell Adhesion Molecules in Severe Mental Illness: Potential Role of Intercellular CAM-1 in Linking Peripheral and Neuroinflammation
Biol Psychiatry, 93 (2), 187-196
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Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium
Schizophr Res, 250, 1-9
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Schizophrenia: genetic insights with clinical potential
Nat Rev Neurol, 18 (3), 129-130
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Borderline personality disorder and the big five: molecular genetic analyses indicate shared genetic architecture with neuroticism and openness
Transl Psychiatry, 12 (1), 153
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Sex- and age-specific associations between cardiometabolic risk and white matter brain age in the UK Biobank cohort
Hum Brain Mapp, 43 (12), 3759-3774
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Inflammation and cognition in severe mental illness: patterns of covariation and subgroups
Mol Psychiatry, 28 (3), 1284-1292
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The Relationship of Maternal Gestational Mass Spectrometry-Derived Metabolites with Offspring Congenital Heart Disease: Results from Multivariable and Mendelian Randomization Analyses
J Cardiovasc Dev Dis, 9 (8)
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The age of violence: Mapping brain age in psychosis and psychopathy
Neuroimage Clin, 36, 103181
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Shared genetic loci between depression and cardiometabolic traits
PLoS Genet, 18 (5), e1010161
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Sex as a Moderator Between Parent Ratings of Executive Dysfunction and Social Difficulties in Children and Adolescents with Autism Spectrum Disorder
J Autism Dev Disord, 53 (10), 3847-3859
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Modeling assortative mating and genetic similarities between partners, siblings, and in-laws
Nat Commun, 13 (1), 1108
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Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Nature, 604 (7906), 502-508
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Cohort Profile: COVIDMENT: COVID-19 cohorts on mental health across six nations
Int J Epidemiol, 51 (3), e108-e122
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Editorial: Cross-disorder Genetics in Neuropsychiatry
Front Neurosci, 16, 826300
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The link between liver fat and cardiometabolic diseases is highlighted by genome-wide association study of MRI-derived measures of body composition
Commun Biol, 5 (1), 1271
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Boosting Schizophrenia Genetics by Utilizing Genetic Overlap With Brain Morphology
Biol Psychiatry, 92 (4), 291-298
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Immune marker levels in severe mental disorders: associations with polygenic risk scores of related mental phenotypes and psoriasis
Transl Psychiatry, 12 (1), 38
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Limited association between infections, autoimmune disease and genetic risk and immune activation in severe mental disorders
Prog Neuropsychopharmacol Biol Psychiatry, 116, 110511
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Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 54 (7), 1062
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Multimodal monitoring of human cortical organoids implanted in mice reveal functional connection with visual cortex
Nat Commun, 13 (1), 7945
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The oxytocin signalling gene pathway contributes to the association between loneliness and cardiometabolic health
Psychoneuroendocrinology, 144, 105875
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Retrospectively assessed childhood trauma experiences are associated with illness severity in mental disorders adjusted for symptom state
Psychiatry Res, 320, 115045
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Publications 2021
Longitudinal Structural Brain Changes in Bipolar Disorder: A Multicenter Neuroimaging Study of 1232 Individuals by the ENIGMA Bipolar Disorder Working Group
Biol Psychiatry, 91 (6), 582-592
DOI 10.1016/j.biopsych.2021.09.008, PubMed 34809987
Transcriptome analysis reveals disparate expression of inflammation-related miRNAs and their gene targets in iPSC-astrocytes from people with schizophrenia
Brain Behav Immun, 94, 235-244
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Cytomegalovirus infection associated with smaller dentate gyrus in men with severe mental illness
Brain Behav Immun, 96, 54-62
DOI 10.1016/j.bbi.2021.05.009, PubMed 34010712
Lower plasma total tau in adolescent psychosis: Involvement of the orbitofrontal cortex
J Psychiatr Res, 144, 255-261
DOI 10.1016/j.jpsychires.2021.10.031, PubMed 34700214
Cytomegalovirus infection and IQ in patients with severe mental illness and healthy individuals
Psychiatry Res, 300, 113929
DOI 10.1016/j.psychres.2021.113929, PubMed 33866186
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
Psychol Med, 53 (4), 1479-1488
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Risk and protective factors for mental disorders beyond genetics: an evidence-based atlas
World Psychiatry, 20 (3), 417-436
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Early manifestations of genetic risk for neurodevelopmental disorders
J Child Psychol Psychiatry, 63 (7), 810-819
DOI 10.1111/jcpp.13528, PubMed 34605010
Genetic loci shared between major depression and intelligence with mixed directions of effect
Nat Hum Behav, 5 (6), 795-801
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In Vivo Amygdala Nuclei Volumes in Schizophrenia and Bipolar Disorders
Schizophr Bull, 47 (5), 1431-1441
DOI 10.1093/schbul/sbaa192, PubMed 33479754
Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder
Int J Bipolar Disord, 9 (1), 26
DOI 10.1186/s40345-021-00231-7, PubMed 34467430
Cardiometabolic risk factors associated with brain age and accelerate brain ageing
Hum Brain Mapp, 43 (2), 700-720
DOI 10.1002/hbm.25680, PubMed 34626047
Associations between amygdala nuclei volumes, psychosis, psychopathy, and violent offending
Psychiatry Res Neuroimaging, 319, 111416
DOI 10.1016/j.pscychresns.2021.111416, PubMed 34847406
Exploring low grade inflammation by soluble urokinase plasminogen activator receptor levels in schizophrenia: a sex-dependent association with depressive symptoms
BMC Psychiatry, 21 (1), 527
DOI 10.1186/s12888-021-03522-6, PubMed 34702245
Elevated levels of soluble urokinase plasminogen activator receptor as a low-grade inflammation marker in schizophrenia: A case-control study
Schizophr Res, 228, 190-192
DOI 10.1016/j.schres.2020.11.051, PubMed 33450603
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J. Affect. Disord., 295, 1032-1039
DOI 10.1016/j.jad.2021.08.135
Telomeres are shorter and associated with number of suicide attempts in affective disorders
J Affect Disord, 295, 1032-1039
DOI 10.1016/j.jad.2021.08.135, PubMed 34706411
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders
Biol Psychiatry, 91 (1), 102-117
DOI 10.1016/j.biopsych.2021.02.972, PubMed 34099189
Sparse deep neural networks on imaging genetics for schizophrenia case-control classification
Hum Brain Mapp, 42 (8), 2556-2568
DOI 10.1002/hbm.25387, PubMed 33724588
Genetic Association Between Schizophrenia and Cortical Brain Surface Area and Thickness
JAMA Psychiatry, 78 (9), 1020-1030
DOI 10.1001/jamapsychiatry.2021.1435, PubMed 34160554
Prominent health problems, socioeconomic deprivation, and higher brain age in lonely and isolated individuals: A population-based study
Behav Brain Res, 414, 113510
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Common variants in Alzheimer's disease and risk stratification by polygenic risk scores
Nat Commun, 12 (1), 3417
DOI 10.1038/s41467-021-22491-8, PubMed 34099642
Genome-wide association identifies the first risk loci for psychosis in Alzheimer disease
Mol Psychiatry, 26 (10), 5797-5811
DOI 10.1038/s41380-021-01152-8, PubMed 34112972
Subcortical volumes across the lifespan: Data from 18,605 healthy individuals aged 3-90 years
Hum Brain Mapp, 43 (1), 452-469
DOI 10.1002/hbm.25320, PubMed 33570244
Associations between depression and cardiometabolic health: A 27-year longitudinal study
Psychol Med, 52 (14), 3007-3017
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The genetic architecture of the human thalamus and its overlap with ten common brain disorders
Nat Commun, 12 (1), 2909
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Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis
JAMA Psychiatry, 78 (7), 753-766
DOI 10.1001/jamapsychiatry.2021.0638, PubMed 33950164
Genetic variants associated with cardiometabolic abnormalities during treatment with selective serotonin reuptake inhibitors: a genome-wide association study
Pharmacogenomics J, 21 (5), 574-585
DOI 10.1038/s41397-021-00234-8, PubMed 33824429
Cortical thickness across the lifespan: Data from 17,075 healthy individuals aged 3-90 years
Hum Brain Mapp, 43 (1), 431-451
DOI 10.1002/hbm.25364, PubMed 33595143
Sex-Specific Effect of Serum Lipids and Body Mass Index on Psychotic Symptoms, a Cross-Sectional Study of First-Episode Psychosis Patients
Front Psychiatry, 12, 723158
DOI 10.3389/fpsyt.2021.723158, PubMed 34744818
Population-based body-brain mapping links brain morphology with anthropometrics and body composition
Transl Psychiatry, 11 (1), 295
DOI 10.1038/s41398-021-01414-7, PubMed 34006848
A meta-analysis of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the ENIGMA Consortium
Hum Brain Mapp, 43 (1), 352-372
DOI 10.1002/hbm.25625, PubMed 34498337
Genetic Liability for Schizophrenia and Childhood Psychopathology in the General Population
Schizophr Bull, 47 (4), 1179-1189
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Developmental milestones in early childhood and genetic liability to neurodevelopmental disorders
Psychol Med, 53 (5), 1750-1758
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Interplay between the Genetics of Personality Traits, severe Psychiatric Disorders, and COVID-19 Host Genetics in the Susceptibility to SARS-CoV-2 Infection - ADDENDUM
BJPsych Open, 7 (6), e206
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Interplay between the genetics of personality traits, severe psychiatric disorders and COVID-19 host genetics in the susceptibility to SARS-CoV-2 infection
BJPsych Open, 7 (6), e188
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Aberrant default mode connectivity in adolescents with early-onset psychosis: A resting state fMRI study
Neuroimage Clin, 33, 102881
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Characterising the shared genetic determinants of bipolar disorder, schizophrenia and risk-taking
Transl Psychiatry, 11 (1), 466
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The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity
Genetics, 217 (3)
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Erratum to: The genetic architecture of human complex phenotypes is modulated by linkage disequilibrium and heterozygosity
Genetics, 218 (2)
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Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
Nat Commun, 12 (1), 1236
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Common genetic and clinical risk factors: association with fatal prostate cancer in the Cohort of Swedish Men
Prostate Cancer Prostatic Dis, 24 (3), 845-851
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Maternal and offspring genetic risk score analyses of fetal alcohol exposure and attention-deficit hyperactivity disorder risk in offspring
Alcohol Clin Exp Res, 45 (10), 2090-2102
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Multivariate alterations in insula - Medial prefrontal cortex linked to genetics in 12q24 in schizophrenia
Psychiatry Res, 306, 114237
DOI 10.1016/j.psychres.2021.114237, PubMed 34655926
Attitudes among parents of persons with autism spectrum disorder towards information about genetic risk and future health
Eur J Hum Genet, 30 (10), 1138-1146
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Characterisation of age and polarity at onset in bipolar disorder
Br J Psychiatry, 219 (6), 659-669
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Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
Prostate Cancer Prostatic Dis, 24 (2), 532-541
DOI 10.1038/s41391-020-00311-2, PubMed 33420416
Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24
Prostate Cancer Prostatic Dis, 25 (2), 229-237
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DSM-5 and ICD-11 criteria for bipolar disorder: Implications for the prevalence of bipolar disorder and validity of the diagnosis - A narrative review from the ECNP bipolar disorders network
Eur Neuropsychopharmacol, 47, 54-61
DOI 10.1016/j.euroneuro.2021.01.097, PubMed 33541809
Dose-dependent transcriptional effects of lithium and adverse effect burden in a psychiatric cohort
Prog Neuropsychopharmacol Biol Psychiatry, 112, 110408
DOI 10.1016/j.pnpbp.2021.110408, PubMed 34320404
Ketamine for depression - evidence and proposals for practice
Tidsskr Nor Laegeforen, 141
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[Not Available]
Tidsskr Nor Laegeforen, 141
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Absolute and Dose-Adjusted Serum Concentrations of Clozapine in Patients Switching vs. Maintaining Treatment: An Observational Study of 1979 Patients
CNS Drugs, 35 (9), 999-1008
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Identifying nootropic drug targets via large-scale cognitive GWAS and transcriptomics
Neuropsychopharmacology, 46 (10), 1788-1801
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The association between bullying and eating disorders: A case-control study
Int J Eat Disord, 54 (8), 1405-1414
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Stressful life events among individuals with a history of eating disorders: a case-control comparison
BMC Psychiatry, 21 (1), 501
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Clinical predictors of non-response to lithium treatment in the Pharmacogenomics of Bipolar Disorder (PGBD) study
Bipolar Disord, 23 (8), 821-831
DOI 10.1111/bdi.13078, PubMed 33797828
Brain age prediction using fMRI network coupling in youths and associations with psychiatric symptoms
Neuroimage Clin, 33, 102921
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Childhood trauma and cardiometabolic risk in severe mental disorders: The mediating role of cognitive control
Eur Psychiatry, 64 (1), e24
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Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information
Biol Psychiatry, 91 (7), 626-636
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Corrigendum to "Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action [European Neuropsychopharmacology (2020) 36, 121-136]"
Eur Neuropsychopharmacol, 44, 121-122
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The genetic structure of Norway
Eur J Hum Genet, 29 (11), 1710-1718
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Diagnosis of bipolar disorders and body mass index predict clustering based on similarities in cortical thickness-ENIGMA study in 2436 individuals
Bipolar Disord, 24 (5), 509-520
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Diphtheria And Tetanus Vaccination History Is Associated With Lower Odds of COVID-19 Hospitalization
Front Immunol, 12, 749264
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Genetic Overlap Between Alzheimer's Disease and Depression Mapped Onto the Brain
Front Neurosci, 15, 653130
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A review of systems biology research of anxiety disorders
Braz J Psychiatry, 43 (4), 414-423
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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Nat Genet, 53 (6), 817-829
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Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
Biol Psychiatry, 91 (3), 313-327
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Multisite reproducibility and test-retest reliability of the T1w/T2w-ratio: A comparison of processing methods
Neuroimage, 245, 118709
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New insights into the dynamic development of the cerebral cortex in childhood and adolescence: Integrating macro- and microstructural MRI findings
Prog Neurobiol, 204, 102109
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Characterizing the Genetic Overlap Between Psychiatric Disorders and Sleep-Related Phenotypes
Biol Psychiatry, 90 (9), 621-631
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Association between complement component 4A expression, cognitive performance and brain imaging measures in UK Biobank
Psychol Med, 52 (15), 1-11 (in press)
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Lithium increases mitochondrial respiration in iPSC-derived neural precursor cells from lithium responders
Mol Psychiatry, 26 (11), 6789-6805
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Genome-wide analyses of smoking behaviors in schizophrenia: Findings from the Psychiatric Genomics Consortium
J Psychiatr Res, 137, 215-224
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Genetic Stratification of Age-Dependent Parkinson's Disease Risk by Polygenic Hazard Score
Mov Disord, 37 (1), 62-69
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Identification of pleiotropy at the gene level between psychiatric disorders and related traits
Transl Psychiatry, 11 (1), 410
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All-Optical Electrophysiology in hiPSC-Derived Neurons With Synthetic Voltage Sensors
Front Cell Neurosci, 15, 671549
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Structural and Pragmatic Language Impairments in Children Evaluated for Autism Spectrum Disorder (ASD)
J Autism Dev Disord, 53 (2), 701-719
DOI 10.1007/s10803-020-04853-1, PubMed 33515169
Outcomes associated with different vaccines in individuals with bipolar disorder and impact on the current COVID-19 pandemic- a systematic review
Eur Neuropsychopharmacol, 54, 90-99
DOI 10.1016/j.euroneuro.2021.09.001, PubMed 34607722
Adiponectin Is Related to Cardiovascular Risk in Severe Mental Illness Independent of Antipsychotic Treatment
Front Psychiatry, 12, 623192
DOI 10.3389/fpsyt.2021.623192, PubMed 34122163
Phenotypically independent profiles relevant to mental health are genetically correlated
Transl Psychiatry, 11 (1), 202
DOI 10.1038/s41398-021-01313-x, PubMed 33795632
Extensive bidirectional genetic overlap between bipolar disorder and cardiovascular disease phenotypes
Transl Psychiatry, 11 (1), 407
DOI 10.1038/s41398-021-01527-z, PubMed 34301917
Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
Transl Psychiatry, 11 (1), 3
DOI 10.1038/s41398-020-01142-4, PubMed 33414458
Vertex-wise multivariate genome-wide association study identifies 780 unique genetic loci associated with cortical morphology
Neuroimage, 244, 118603
DOI 10.1016/j.neuroimage.2021.118603, PubMed 34560273
Neuropsychiatric symptoms and brain morphology in patients with mild cognitive impairment and Alzheimer's disease with dementia
Int Psychogeriatr, 33 (11), 1217-1228
DOI 10.1017/S1041610221000934, PubMed 34399870
Polygenic risk scores in psychiatry - Large potential but still limited clinical utility
Eur Neuropsychopharmacol, 51, 68-70
DOI 10.1016/j.euroneuro.2021.05.007, PubMed 34091254
Cognitive impairment profile in adolescent early-onset psychosis using the MATRICS Battery: Age and sex effects
Neuropsychology, 35 (3), 300-309
DOI 10.1037/neu0000723, PubMed 33970663
Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity
Brain Behav, 11 (8), e02188
DOI 10.1002/brb3.2188, PubMed 34291596
Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis
Front Neurosci, 15, 678503
DOI 10.3389/fnins.2021.678503, PubMed 34248484
A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
Transl Psychiatry, 11 (1), 554
DOI 10.1038/s41398-021-01681-4, PubMed 34716291
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA working groups on CNVs
Hum Brain Mapp, 43 (1), 300-328
DOI 10.1002/hbm.25354, PubMed 33615640
1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans
Transl Psychiatry, 11 (1), 182
DOI 10.1038/s41398-021-01213-0, PubMed 33753722
ENIGMA-Sleep: Challenges, opportunities, and the road map
J Sleep Res, 30 (6), e13347
DOI 10.1111/jsr.13347, PubMed 33913199
Shared genetic architecture between neuroticism, coronary artery disease and cardiovascular risk factors
Transl Psychiatry, 11 (1), 368
DOI 10.1038/s41398-021-01466-9, PubMed 34226488
Evidence for Reduced Long-Term Potentiation-Like Visual Cortical Plasticity in Schizophrenia and Bipolar Disorder
Schizophr Bull, 47 (6), 1751-1760
DOI 10.1093/schbul/sbab049, PubMed 33963856
The genetic architecture of human cortical folding
Sci Adv, 7 (51), eabj9446
DOI 10.1126/sciadv.abj9446, PubMed 34910505
The factor structure of social cognition in schizophrenia: Weak evidence for separable domains
Schizophr Res Cogn, 26, 100208
DOI 10.1016/j.scog.2021.100208, PubMed 34430229
Similar Genetic Architecture of Alzheimer's Disease and Differential APOE Effect Between Sexes
Front Aging Neurosci, 13, 674318
DOI 10.3389/fnagi.2021.674318, PubMed 34122051
Causal association of cognitive reserve on Alzheimer's disease with putative sex difference
Alzheimers Dement (Amst), 13 (1), e12270
DOI 10.1002/dad2.12270, PubMed 35005200
Common Genetic Variation and Age of Onset of Anorexia Nervosa
Biol Psychiatry Glob Open Sci, 2 (4), 368-378
DOI 10.1016/j.bpsgos.2021.09.001, PubMed 36324647
A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (9), 1276-1282
DOI 10.1038/s41588-021-00921-z, PubMed 34493870
Author Correction: A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease
Nat Genet, 53 (12), 1722
DOI 10.1038/s41588-021-00977-x, PubMed 34773122
12-year prediction of mild cognitive impairment aided by Alzheimer's brain signatures at mean age 56
Brain Commun, 3 (3), fcab167
DOI 10.1093/braincomms/fcab167, PubMed 34396116
Oxytocin-pathway polygenic scores for severe mental disorders and metabolic phenotypes in the UK Biobank
Transl Psychiatry, 11 (1), 599
DOI 10.1038/s41398-021-01725-9, PubMed 34824196
Psychometric properties of the Norwegian version of the Patient Health Questionnaire-9 (PHQ-9) in a large female sample of adults with and without eating disorders
BMC Psychiatry, 21 (1), 6
DOI 10.1186/s12888-020-03013-0, PubMed 33402149
Genome-wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci
Addiction, 117 (3), 600-610
DOI 10.1111/add.15680, PubMed 34472679
Replicating extensive brain structural heterogeneity in individuals with schizophrenia and bipolar disorder
Hum Brain Mapp, 42 (8), 2546-2555
DOI 10.1002/hbm.25386, PubMed 33638594
Association of Birth Asphyxia With Regional White Matter Abnormalities Among Patients With Schizophrenia and Bipolar Disorders
JAMA Netw Open, 4 (12), e2139759
DOI 10.1001/jamanetworkopen.2021.39759, PubMed 34928356
Significant association between intracranial volume and verbal intellectual abilities in patients with schizophrenia and a history of birth asphyxia
Psychol Med, 52 (15), 1-10 (in press)
DOI 10.1017/S0033291721000489, PubMed 33750510
Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders
JAMA Psychiatry, 78 (1), 47-63
DOI 10.1001/jamapsychiatry.2020.2694, PubMed 32857118
Gut microbial biomarkers for the treatment response in first-episode, drug-naïve schizophrenia: a 24-week follow-up study
Transl Psychiatry, 11 (1), 422
DOI 10.1038/s41398-021-01531-3, PubMed 34376634
Physical activity and childhood trauma experiences in patients with schizophrenia or bipolar disorders
World J Biol Psychiatry, 22 (8), 637-645
DOI 10.1080/15622975.2021.1907707, PubMed 33779484
Publications 2020
Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells
Brain Behav Immun, 87, 634-644
DOI 10.1016/j.bbi.2020.02.008, PubMed 32109548
The effects of cognitive abilities and task demands on tonic and phasic pupil sizes
Biol Psychol, 156, 107945
DOI 10.1016/j.biopsycho.2020.107945, PubMed 32889001
Shared Genetic Loci Between Body Mass Index and Major Psychiatric Disorders: A Genome-wide Association Study
JAMA Psychiatry, 77 (5), 503-512
DOI 10.1001/jamapsychiatry.2019.4188, PubMed 31913414
Exploring white matter microstructure and the impact of antipsychotics in adolescent-onset psychosis
PLoS One, 15 (5), e0233684
DOI 10.1371/journal.pone.0233684, PubMed 32470000
White matter microstructure across the adult lifespan: A mixed longitudinal and cross-sectional study using advanced diffusion models and brain-age prediction
Neuroimage, 224, 117441
DOI 10.1016/j.neuroimage.2020.117441, PubMed 33039618
Heart rate variability is associated with disease severity in psychosis spectrum disorders
Prog Neuropsychopharmacol Biol Psychiatry, 111, 110108
DOI 10.1016/j.pnpbp.2020.110108, PubMed 32946948
How important are parents in the development of child anxiety and depression? A genomic analysis of parent-offspring trios in the Norwegian Mother Father and Child Cohort Study (MoBa)
BMC Med, 18 (1), 284
DOI 10.1186/s12916-020-01760-1, PubMed 33106172
What we learn about bipolar disorder from large-scale neuroimaging: Findings and future directions from the ENIGMA Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 56-82
DOI 10.1002/hbm.25098, PubMed 32725849
Genetic control of variability in subcortical and intracranial volumes
Mol Psychiatry, 26 (8), 3876-3883
DOI 10.1038/s41380-020-0664-1, PubMed 32047264
Genome-wide association study identifies 48 common genetic variants associated with handedness
Nat Hum Behav, 5 (1), 59-70
DOI 10.1038/s41562-020-00956-y, PubMed 32989287
Intelligence, educational attainment, and brain structure in those at familial high-risk for schizophrenia or bipolar disorder
Hum Brain Mapp, 43 (1), 414-430
DOI 10.1002/hbm.25206, PubMed 33027543
Exploring the Effects of an Acute Dose of Antipsychotic Medication on Motivation-mediated BOLD Activity Using fMRI and a Perceptual Decision-making Task
Neuroscience, 440, 146-159
DOI 10.1016/j.neuroscience.2020.05.035, PubMed 32473275
Differences in course of illness between patients with bipolar II disorder with and without epileptiform discharges or other sharp activity on electroencephalograms: a cross-sectional study
BMC Psychiatry, 20 (1), 582
DOI 10.1186/s12888-020-02968-4, PubMed 33287748
The genetic architecture of human brainstem structures and their involvement in common brain disorders
Nat Commun, 11 (1), 4016
DOI 10.1038/s41467-020-17376-1, PubMed 32782260
Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls
Transl Psychiatry, 10 (1), 416
DOI 10.1038/s41398-020-01094-9, PubMed 33257657
Sex-dependent autosomal effects on clinical progression of Alzheimer's disease
Brain, 143 (7), 2272-2280
DOI 10.1093/brain/awaa164, PubMed 32591829
Social Perception Predicts Awareness of Illness in Persons With Schizophrenia
J Nerv Ment Dis, 208 (9), 701-705
DOI 10.1097/NMD.0000000000001185, PubMed 32433201
The genetic architecture of the human cerebral cortex
Science, 367 (6484)
DOI 10.1126/science.aay6690, PubMed 32193296
Intracranial and subcortical volumes in adolescents with early-onset psychosis: A multisite mega-analysis from the ENIGMA consortium
Hum Brain Mapp, 43 (1), 373-384
DOI 10.1002/hbm.25212, PubMed 33017498
Computationally efficient familywise error rate control in genome-wide association studies using score tests for generalized linear models
Scand. J. Stat., 47 (4), 1090-1113
DOI 10.1111/sjos.12451
Brain aging in major depressive disorder: results from the ENIGMA major depressive disorder working group
Mol Psychiatry, 26 (9), 5124-5139
DOI 10.1038/s41380-020-0754-0, PubMed 32424236
In vivo hippocampal subfield volumes in bipolar disorder-A mega-analysis from The Enhancing Neuro Imaging Genetics through Meta-Analysis Bipolar Disorder Working Group
Hum Brain Mapp, 43 (1), 385-398
DOI 10.1002/hbm.25249, PubMed 33073925
Disentangling the relationship between cholesterol, aggression, and impulsivity in severe mental disorders
Brain Behav, 10 (9), e01751
DOI 10.1002/brb3.1751, PubMed 32681586
Childhood trauma is associated with poorer social functioning in severe mental disorders both during an active illness phase and in remission
Schizophr Res, 243, 241-246
DOI 10.1016/j.schres.2020.03.015, PubMed 32222348
Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults
Nat Commun, 11 (1), 4796
DOI 10.1038/s41467-020-18367-y, PubMed 32963231
Beyond SNP heritability: Polygenicity and discoverability of phenotypes estimated with a univariate Gaussian mixture model
PLoS Genet, 16 (5), e1008612
DOI 10.1371/journal.pgen.1008612, PubMed 32427991
The Relationship Between White Matter Microstructure and General Cognitive Ability in Patients With Schizophrenia and Healthy Participants in the ENIGMA Consortium
Am J Psychiatry, 177 (6), 537-547
DOI 10.1176/appi.ajp.2019.19030225, PubMed 32212855
Higher vitamin B12 levels in neurodevelopmental disorders than in healthy controls and schizophrenia: A comparison among participants between 2 and 53 years
FASEB J, 34 (6), 8114-8124
DOI 10.1096/fj.201900855RRR, PubMed 32323402
A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data
Cancer Epidemiol Biomarkers Prev, 29 (9), 1731-1738
DOI 10.1158/1055-9965.EPI-19-1527, PubMed 32581112
Age dependence of modern clinical risk groups for localized prostate cancer-A population-based study
Cancer, 126 (8), 1691-1699
DOI 10.1002/cncr.32702, PubMed 31899813
Differences in the Presentation and Progression of Parkinson's Disease by Sex
Mov Disord, 36 (1), 106-117
DOI 10.1002/mds.28312, PubMed 33002231
Author Correction: Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
Nat Genet, 52 (3), 354
DOI 10.1038/s41588-019-0573-x, PubMed 32029921
The effect of sample size on polygenic hazard models for prostate cancer
Eur J Hum Genet, 28 (10), 1467-1475
DOI 10.1038/s41431-020-0664-2, PubMed 32514134
African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer
Int J Cancer, 148 (1), 99-105
DOI 10.1002/ijc.33282, PubMed 32930425
Publisher Correction: Common brain disorders are associated with heritable patterns of apparent aging of the brain
Nat Neurosci, 23 (2), 295
DOI 10.1038/s41593-019-0553-6, PubMed 31848485
ENIGMA-DTI: Translating reproducible white matter deficits into personalized vulnerability metrics in cross-diagnostic psychiatric research
Hum Brain Mapp, 43 (1), 194-206
DOI 10.1002/hbm.24998, PubMed 32301246
Cortical thickness and resting-state cardiac function across the lifespan: A cross-sectional pooled mega-analysis
Psychophysiology, 58 (7), e13688
DOI 10.1111/psyp.13688, PubMed 33037836
Undetectable or subtherapeutic serum levels of antipsychotic drugs preceding switch to clozapine
NPJ Schizophr, 6 (1), 17
DOI 10.1038/s41537-020-0107-7, PubMed 32681055
Brain structural correlates of insomnia severity in 1053 individuals with major depressive disorder: results from the ENIGMA MDD Working Group
Transl Psychiatry, 10 (1), 425
DOI 10.1038/s41398-020-01109-5, PubMed 33293520
Pleiotropy of polygenic factors associated with focal and generalized epilepsy in the general population
PLoS One, 15 (4), e0232292
DOI 10.1371/journal.pone.0232292, PubMed 32343744
Differences in directed functional brain connectivity related to age, sex and mental health
Hum Brain Mapp, 41 (15), 4173-4186
DOI 10.1002/hbm.25116, PubMed 32613721
Associations between schizophrenia polygenic risk and apathy in schizophrenia spectrum disorders and healthy controls
Acta Psychiatr Scand, 141 (5), 452-464
DOI 10.1111/acps.13167, PubMed 32091622
Translating big data to better treatment in bipolar disorder - a manifesto for coordinated action
Eur Neuropsychopharmacol, 36, 121-136
DOI 10.1016/j.euroneuro.2020.05.006, PubMed 32536571
Interleukin 18 (IL-18) and its binding protein (IL-18BP) are increased in patients with epilepsy suggesting low-grade systemic inflammation
Seizure, 80, 221-225
DOI 10.1016/j.seizure.2020.05.018, PubMed 32659652
Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies
Addict Biol, 26 (1), e12880
DOI 10.1111/adb.12880, PubMed 32064741
The role of norepinephrine in the pathophysiology of schizophrenia
Neurosci Biobehav Rev, 118, 298-314
DOI 10.1016/j.neubiorev.2020.07.038, PubMed 32768486
Maturation of cortical microstructure and cognitive development in childhood and adolescence: A T1w/T2w ratio MRI study
Hum Brain Mapp, 41 (16), 4676-4690
DOI 10.1002/hbm.25149, PubMed 32744409
Testing relationships between multimodal modes of brain structural variation and age, sex and polygenic scores for neuroticism in children and adolescents
Transl Psychiatry, 10 (1), 251
DOI 10.1038/s41398-020-00931-1, PubMed 32710012
Age of First Walking and Associations with Symptom Severity in Children with Suspected or Diagnosed Autism Spectrum Disorder
J Autism Dev Disord, 50 (9), 3216-3232
DOI 10.1007/s10803-019-04112-y, PubMed 31278523
Atherogenic Lipid Ratios Related to Myeloperoxidase and C-Reactive Protein Levels in Psychotic Disorders
Front Psychiatry, 11, 672
DOI 10.3389/fpsyt.2020.00672, PubMed 32754070
The Relationship Between Polygenic Risk Scores and Cognition in Schizophrenia
Schizophr Bull, 46 (2), 336-344
DOI 10.1093/schbul/sbz061, PubMed 31206164
Multimodal imaging improves brain age prediction and reveals distinct abnormalities in patients with psychiatric and neurological disorders
Hum Brain Mapp, 42 (6), 1714-1726
DOI 10.1002/hbm.25323, PubMed 33340180
Identifying multimodal signatures underlying the somatic comorbidity of psychosis: the COMMITMENT roadmap
Mol Psychiatry, 26 (3), 722-724
DOI 10.1038/s41380-020-00915-z, PubMed 33060817
Phenotype-specific differences in polygenicity and effect size distribution across functional annotation categories revealed by AI-MiXeR
Bioinformatics, 36 (18), 4749-4756
DOI 10.1093/bioinformatics/btaa568, PubMed 32539089
Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease
Mov Disord, 36 (2), 449-459
DOI 10.1002/mds.28338, PubMed 33107653
Nonsocial cognitive underpinnings of theory of mind in schizophrenia
Psychiatry Res, 289, 113055
DOI 10.1016/j.psychres.2020.113055, PubMed 32446008
Correction: Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 914
DOI 10.1038/s41380-019-0456-7, PubMed 31308466
The polygenic architecture of schizophrenia - rethinking pathogenesis and nosology
Nat Rev Neurol, 16 (7), 366-379
DOI 10.1038/s41582-020-0364-0, PubMed 32528109
Genome-wide Association Analysis of Parkinson's Disease and Schizophrenia Reveals Shared Genetic Architecture and Identifies Novel Risk Loci
Biol Psychiatry, 89 (3), 227-235
DOI 10.1016/j.biopsych.2020.01.026, PubMed 32201043
Negative and disorganized symptoms mediate the relationship between verbal learning and global functioning in adolescents with early-onset psychosis
Eur Child Adolesc Psychiatry, 29 (12), 1693-1703
DOI 10.1007/s00787-020-01479-7, PubMed 32036438
Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 198
DOI 10.1038/s41398-020-00888-1, PubMed 32555152
Correction: Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits
Transl Psychiatry, 10 (1), 366
DOI 10.1038/s41398-020-01061-4, PubMed 33139722
Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs - A study based on blood sample analyses from 24,239 patients
Eur Neuropsychopharmacol, 37, 64-69
DOI 10.1016/j.euroneuro.2020.06.007, PubMed 32595082
Rates of complete nonadherence among atypical antipsychotic drugs: A study using blood samples from 13,217 outpatients with psychotic disorders
Schizophr Res, 228, 590-596
DOI 10.1016/j.schres.2020.11.025, PubMed 33221147
Childhood Trauma in Persons With Schizophrenia and a History of Interpersonal Violence
Front Psychiatry, 11, 383
DOI 10.3389/fpsyt.2020.00383, PubMed 32431632
Cannabis Use Is Associated With Increased Levels of Soluble gp130 in Schizophrenia but Not in Bipolar Disorder
Front Psychiatry, 11, 642
DOI 10.3389/fpsyt.2020.00642, PubMed 32714224
Exploring neurophysiological markers of visual perspective taking: Methodological considerations
Int J Psychophysiol, 161, 1-12
DOI 10.1016/j.ijpsycho.2020.12.006, PubMed 33388368
Correction: Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
Mol Psychiatry, 25 (3), 692-695
DOI 10.1038/s41380-019-0358-8, PubMed 30705424
Insulin Resistance and Oxidative Stress: In Relation to Cognitive Function and Psychopathology in Drug-Naïve, First-Episode Drug-Free Schizophrenia
Front Psychiatry, 11, 537280
DOI 10.3389/fpsyt.2020.537280, PubMed 33329081
Hippocampal subfield and amygdala nuclei volumes in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 270 (6), 771-782
DOI 10.1007/s00406-020-01098-y, PubMed 31980898
ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
Transl Psychiatry, 10 (1), 100
DOI 10.1038/s41398-020-0705-1, PubMed 32198361
Brain Age Prediction Reveals Aberrant Brain White Matter in Schizophrenia and Bipolar Disorder: A Multisample Diffusion Tensor Imaging Study
Biol Psychiatry Cogn Neurosci Neuroimaging, 5 (12), 1095-1103
DOI 10.1016/j.bpsc.2020.06.014, PubMed 32859549
Experience-dependent modulation of the visual evoked potential: Testing effect sizes, retention over time, and associations with age in 415 healthy individuals
Neuroimage, 223, 117302
DOI 10.1016/j.neuroimage.2020.117302, PubMed 32828930
Quantifying the Polygenic Architecture of the Human Cerebral Cortex: Extensive Genetic Overlap between Cortical Thickness and Surface Area
Cereb Cortex, 30 (10), 5597-5603
DOI 10.1093/cercor/bhaa146, PubMed 32483632
Understanding the genetic determinants of the brain with MOSTest
Nat Commun, 11 (1), 3512
DOI 10.1038/s41467-020-17368-1, PubMed 32665545
Author Correction: Understanding the genetic determinants of the brain with MOSTest
Nat Commun, 11 (1), 4700
DOI 10.1038/s41467-020-18628-w, PubMed 32929091
Cognitive Heterogeneity across Schizophrenia and Bipolar Disorder: A Cluster Analysis of Intellectual Trajectories
J Int Neuropsychol Soc, 26 (9), 860-872
DOI 10.1017/S1355617720000442, PubMed 32423506
Genome-wide association study identifies 16 genomic regions associated with circulating cytokines at birth
PLoS Genet, 16 (11), e1009163
DOI 10.1371/journal.pgen.1009163, PubMed 33227023
Author Correction: A global overview of pleiotropy and genetic architecture in complex traits
Nat Genet, 52 (3), 353
DOI 10.1038/s41588-019-0571-z, PubMed 32029922
Reduced levels of circulating adhesion molecules in adolescents with early-onset psychosis
NPJ Schizophr, 6 (1), 20
DOI 10.1038/s41537-020-00112-5, PubMed 32811840
Indicated association between polygenic risk score and treatment-resistance in a naturalistic sample of patients with schizophrenia spectrum disorders
Schizophr Res, 218, 55-62
DOI 10.1016/j.schres.2020.03.006, PubMed 32171635
Greater male than female variability in regional brain structure across the lifespan
Hum Brain Mapp, 43 (1), 470-499
DOI 10.1002/hbm.25204, PubMed 33044802
Associations of loneliness and social isolation with cardiovascular and metabolic health: a systematic review and meta-analysis protocol
Syst Rev, 9 (1), 102
DOI 10.1186/s13643-020-01369-8, PubMed 32366295
Improving the precision of intranasal oxytocin research
Nat Hum Behav, 5 (1), 9-18
DOI 10.1038/s41562-020-00996-4, PubMed 33257880
Asphyxia at birth affects brain structure in patients on the schizophrenia-bipolar disorder spectrum and healthy participants
Psychol Med, 52 (6), 1050-1059
DOI 10.1017/S0033291720002779, PubMed 32772969
Association of Copy Number Variation of the 15q11.2 BP1-BP2 Region With Cortical and Subcortical Morphology and Cognition
JAMA Psychiatry, 77 (4), 420-430
DOI 10.1001/jamapsychiatry.2019.3779, PubMed 31665216
Childhood Trauma Is Nominally Associated With Elevated Cortisol Metabolism in Severe Mental Disorder
Front Psychiatry, 11, 391
DOI 10.3389/fpsyt.2020.00391, PubMed 32528319
Publications 2019
Exploring lithium's transcriptional mechanisms of action in bipolar disorder: a multi-step study
Neuropsychopharmacology, 45 (6), 947-955
DOI 10.1038/s41386-019-0556-8, PubMed 31652432
Brain Heterogeneity in Schizophrenia and Its Association With Polygenic Risk
JAMA Psychiatry, 76 (7), 739-748
DOI 10.1001/jamapsychiatry.2019.0257, PubMed 30969333
Association between solar insolation and a history of suicide attempts in bipolar I disorder
J Psychiatr Res, 113, 1-9
DOI 10.1016/j.jpsychires.2019.03.001, PubMed 30878786
Shared Genetic Risk of Schizophrenia and Gray Matter Reduction in 6p22.1
Schizophr Bull, 45 (1), 222-232
DOI 10.1093/schbul/sby010, PubMed 29474680
Examining the association between genetic liability for schizophrenia and psychotic symptoms in Alzheimer's disease
Transl Psychiatry, 9 (1), 273
DOI 10.1038/s41398-019-0592-5, PubMed 31641104
Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 10 (1), 2068
DOI 10.1038/s41467-019-10160-w, PubMed 31043617
Population-based neuroimaging reveals traces of childbirth in the maternal brain
Proc Natl Acad Sci U S A, 116 (44), 22341-22346
DOI 10.1073/pnas.1910666116, PubMed 31615888
The Association Between Familial Risk and Brain Abnormalities Is Disease Specific: An ENIGMA-Relatives Study of Schizophrenia and Bipolar Disorder
Biol Psychiatry, 86 (7), 545-556
DOI 10.1016/j.biopsych.2019.03.985, PubMed 31443932
Antipsychotic treatment and basal ganglia volumes: Exploring the role of receptor occupancy, dosage and remission status
Schizophr Res, 208, 114-123
DOI 10.1016/j.schres.2019.04.002, PubMed 31006616
Genetic Overlap Between Alzheimer's Disease and Bipolar Disorder Implicates the MARK2 and VAC14 Genes
Front Neurosci, 13, 220
DOI 10.3389/fnins.2019.00220, PubMed 30930738
Genetic risk for coronary heart disease alters the influence of Alzheimer's genetic risk on mild cognitive impairment
Neurobiol Aging, 84, 237.e5-237.e12
DOI 10.1016/j.neurobiolaging.2019.06.001, PubMed 31272697
Objectively Assessed Daily Steps-Not Light Intensity Physical Activity, Moderate-to-Vigorous Physical Activity and Sedentary Time-Is Associated With Cardiorespiratory Fitness in Patients With Schizophrenia
Front Psychiatry, 10, 82
DOI 10.3389/fpsyt.2019.00082, PubMed 30863327
Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals
Neuropsychopharmacology, 44 (13), 2285-2293
DOI 10.1038/s41386-019-0485-6, PubMed 31434102
Correction: Widespread white matter microstructural abnormalities in bipolar disorder: evidence from mega- and meta-analyses across 3033 individuals
Neuropsychopharmacology, 44 (13), 2298
DOI 10.1038/s41386-019-0521-6, PubMed 31527792
Bivariate causal mixture model quantifies polygenic overlap between complex traits beyond genetic correlation
Nat Commun, 10 (1), 2417
DOI 10.1038/s41467-019-10310-0, PubMed 31160569
Theory of mind in schizophrenia and bipolar disorder: psychometric properties of the Norwegian version of the Hinting Task
Cogn Neuropsychiatry, 24 (6), 454-469
DOI 10.1080/13546805.2019.1674645, PubMed 31578118
Improvement in verbal learning over the first year of antipsychotic treatment is associated with serum HDL levels in a cohort of first episode psychosis patients
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Association between leptin levels and severity of suicidal behaviour in schizophrenia spectrum disorders
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Identification of common genetic risk variants for autism spectrum disorder
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Attention-deficit hyperactivity disorder shares copy number variant risk with schizophrenia and autism spectrum disorder
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The Association Between Cardiorespiratory Fitness and Cognition Appears Neither Related to Current Physical Activity Nor Mediated by Brain-Derived Neurotrophic Factor in a Sample of Outpatients With Schizophrenia
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Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder
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The association between hippocampal subfield volumes in mild cognitive impairment and conversion to Alzheimer's disease
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Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk
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Distinct structural brain circuits indicate mood and apathy profiles in bipolar disorder
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Common brain disorders are associated with heritable patterns of apparent aging of the brain
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Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways
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Sleep disturbances in schizophrenia spectrum and bipolar disorders - a transdiagnostic perspective
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Brain Connectome Mapping of Complex Human Traits and Their Polygenic Architecture Using Machine Learning
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Cerebellar Gray Matter Volume Is Associated With Cognitive Function and Psychopathology in Adolescence
Biol Psychiatry, 86 (1), 65-75
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GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores
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Computational Modeling of Genetic Contributions to Excitability and Neural Coding in Layer V Pyramidal Cells: Applications to Schizophrenia Pathology
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Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders
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Alterations in Schizophrenia-Associated Genes Can Lead to Increased Power in Delta Oscillations
Cereb Cortex, 29 (2), 875-891
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Inflammatory markers are altered in severe mental disorders independent of comorbid cardiometabolic disease risk factors
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Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci
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Roadmap for a precision-medicine initiative in the Nordic region
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Identification of genetic overlap and novel risk loci for attention-deficit/hyperactivity disorder and bipolar disorder
Mol Psychiatry, 26 (8), 4055-4065
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Identification of Genetic Loci Shared Between Attention-Deficit/Hyperactivity Disorder, Intelligence, and Educational Attainment
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Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nat Genet, 51 (7), 1193
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Association of Economic Status and Educational Attainment With Posttraumatic Stress Disorder A Mendelian Randomization Study
JAMA Netw. Open, 2 (5), e193447
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Oxytocin pathway gene networks in the human brain
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GBA and APOE ε4 associate with sporadic dementia with Lewy bodies in European genome wide association study
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Sci Rep, 9 (1), 15168
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Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade
Acta Psychiatr Scand, 139 (4), 348-360
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GWASinlps: non-local prior based iterative SNP selection tool for genome-wide association studies
Bioinformatics, 35 (1), 1-11
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Genetic architecture of subcortical brain structures in 38,851 individuals
Nat Genet, 51 (11), 1624-1636
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Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder
Transl Psychiatry, 9 (1), 12
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Prospective cohort study of early biosignatures of response to lithium in bipolar-I-disorders: overview of the H2020-funded R-LiNK initiative
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Perceived and experienced stigma in first-episode psychosis: A 1-year follow-up study
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Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence
Mol Psychiatry, 25 (4), 844-853
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The emerging pattern of shared polygenic architecture of psychiatric disorders, conceptual and methodological challenges
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Discovery of shared genomic loci using the conditional false discovery rate approach
Hum Genet, 139 (1), 85-94
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Healthy Adolescent Performance With Standardized Scoring Tables for the MATRICS Consensus Cognitive Battery: A Multisite Study
Schizophr Bull, 45 (4), 773-783
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Reduction in N-Desmethylclozapine Level Is Determined by Daily Dose But Not Serum Concentration of Valproic Acid-Indications of a Presystemic Interaction Mechanism
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Correction to: Psychiatric genetics and the structure of psychopathology
Mol Psychiatry, 24 (3), 471
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A five-year follow-up study of antioxidants, oxidative stress and polyunsaturated fatty acids in schizophrenia
Acta Neuropsychiatr, 31 (4), 202-212
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Genome-wide association study identifies 30 loci associated with bipolar disorder
Nat Genet, 51 (5), 793-803
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Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders
Psychol Med, 50 (4), 595-606
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A preliminary study of cortical morphology in schizophrenia patients with a history of violence
Psychiatry Res Neuroimaging, 288, 29-36
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Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration
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White matter microstructure in schizophrenia patients with a history of violence
Eur Arch Psychiatry Clin Neurosci, 271 (4), 623-634
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Autism spectrum disorder polygenic scores are associated with every day executive function in children admitted for clinical assessment
Autism Res, 13 (2), 207-220
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A randomized controlled trial of training of affect recognition (TAR) in schizophrenia shows lasting effects for theory of mind
Eur Arch Psychiatry Clin Neurosci, 269 (5), 611-620
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Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI
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Post-traumatic stress following military deployment: Genetic associations and cross-disorder genetic correlations
J Affect Disord, 252, 350-357
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A global overview of pleiotropy and genetic architecture in complex traits
Nat Genet, 51 (9), 1339-1348
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Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Nat Genet, 51 (8), 1207-1214
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Lipid alterations in adolescents with early-onset psychosis may be independent of antipsychotic medication
Schizophr Res, 216, 295-301
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Increased interleukin 18 activity in adolescents with early-onset psychosis is associated with cortisol and depressive symptoms
Psychoneuroendocrinology, 112, 104513
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Population-Based Mapping of Polygenic Risk for Schizophrenia on the Human Brain: New Opportunities to Capture the Dimensional Aspects of Severe Mental Disorders
Biol Psychiatry, 86 (7), 499-501
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Obstetric complications and intelligence in patients on the schizophrenia-bipolar spectrum and healthy participants
Psychol Med, 50 (11), 1914-1922
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Mood episodes are associated with increased cortical thinning: A longitudinal study of bipolar disorder type II
Bipolar Disord, 21 (6), 525-538
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Childhood maltreatment and polygenic risk in bipolar disorders
Bipolar Disord, 22 (2), 174-181
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The relationship between physical activity, clinical and cognitive characteristics and BDNF mRNA levels in patients with severe mental disorders
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Telomere length is associated with childhood trauma in patients with severe mental disorders
Transl Psychiatry, 9 (1), 97
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Elevated hair cortisol is associated with childhood maltreatment and cognitive impairment in schizophrenia and in bipolar disorders
Schizophr Res, 213, 65-71
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Publications 2018
Expression of TCN1 in Blood is Negatively Associated with Verbal Declarative Memory Performance
Sci Rep, 8 (1), 12654
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Association of Heritable Cognitive Ability and Psychopathology With White Matter Properties in Children and Adolescents
JAMA Psychiatry, 75 (3), 287-295
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Recently evolved human-specific methylated regions are enriched in schizophrenia signals
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Analysis of differentially methylated regions in great apes and extinct hominids provides support for the evolutionary hypothesis of schizophrenia
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Areas of uncertainties and unmet needs in bipolar disorders: clinical and research perspectives
Lancet Psychiatry, 5 (11), 930-939
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Vitamin D levels, brain volume, and genetic architecture in patients with psychosis
PLoS One, 13 (8), e0200250
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Cross-tissue eQTL enrichment of associations in schizophrenia
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CXCR4 involvement in neurodegenerative diseases
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Analysis of shared heritability in common disorders of the brain
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Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
PLoS Med, 15 (1), e1002487
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Correction: Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies
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Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease
Acta Neuropathol, 137 (2), 209-226
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Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories
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Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
Nat Commun, 9 (1), 2098
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Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
Nat Genet, 51 (1), 63-75
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An association between YKL-40 and type 2 diabetes in psychotic disorders
Acta Psychiatr Scand, 139 (1), 37-45
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Clinical characteristics of patients with bipolar disorder and premorbid traumatic brain injury: a cross-sectional study
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Reliability and validity of the self-report version of the apathy evaluation scale in first-episode Psychosis: Concordance with the clinical version at baseline and 12 months follow-up
Psychiatry Res, 267, 140-147
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Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes
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Beyond heritability: improving discoverability in imaging genetics
Hum Mol Genet, 27 (R1), R22-R28
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Association between olanzapine treatment and brain cortical thickness and gray/white matter contrast is moderated by cholesterol in psychotic disorders
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Gjestad et al. reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker
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Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders
Eur Arch Psychiatry Clin Neurosci, 269 (7), 795-802
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Hippocampus volume reduction in psychosis spectrum could be ameliorated by vitamin D
Schizophr Res, 199, 433-435
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Vitamin D, Folate and the Intracranial Volume in Schizophrenia and Bipolar Disorder and Healthy Controls
Sci Rep, 8 (1), 10817
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Cardio-respiratory fitness is associated with a verbal factor across cognitive domains in schizophrenia
Schizophr Res, 206, 157-162
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Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder
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Attenuated Notch signaling in schizophrenia and bipolar disorder
Sci Rep, 8 (1), 5349
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Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder
Transl Psychiatry, 8 (1), 210
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Widespread white matter changes in post-H1N1 patients with narcolepsy type 1 and first-degree relatives
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Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum
JAMA Neurol, 75 (7), 860-875
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Stability of the Brain Functional Connectome Fingerprint in Individuals With Schizophrenia
JAMA Psychiatry, 75 (7), 749-751
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Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease
Front Neurosci, 12, 260
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Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia
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Key Brain Network Nodes Show Differential Cognitive Relevance and Developmental Trajectories during Childhood and Adolescence
eNeuro, 5 (4)
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In Vivo Two-Photon Voltage Imaging with Sulfonated Rhodamine Dyes
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Psychedelic drugs in the treatment of anxiety, depression and addiction
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Psychedelic drugs in the treatment of anxiety, depression and addiction
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Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)
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A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework
BMC Genomics, 19 (1), 494
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A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia
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Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex
Sci Rep, 8 (1), 13373
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Use of an Alzheimer's disease polygenic risk score to identify mild cognitive impairment in adults in their 50s
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Cortical thickness abnormalities in bipolar disorder patients with a lifetime history of auditory hallucinations
Bipolar Disord, 20 (7), 647-657
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Probing Brain Developmental Patterns of Myelination and Associations With Psychopathology in Youths Using Gray/White Matter Contrast
Biol Psychiatry, 85 (5), 389-398
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Using structural MRI to identify bipolar disorders - 13 site machine learning study in 3020 individuals from the ENIGMA Bipolar Disorders Working Group
Mol Psychiatry, 25 (9), 2130-2143
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Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
Nat Genet, 50 (3), 381-389
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Evidence for intranasal oxytocin delivery to the brain: recent advances and future perspectives
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The Promise of Intranasal Esketamine as a Novel and Effective Antidepressant
JAMA Psychiatry, 75 (2), 123-124
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Low-dose intranasal oxytocin delivered with Breath Powered device modulates pupil diameter and amygdala activity: a randomized controlled pupillometry and fMRI study
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Saliva oxytocin measures do not reflect peripheral plasma concentrations after intranasal oxytocin administration in men
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Assessing distinct patterns of cognitive aging using tissue-specific brain age prediction based on diffusion tensor imaging and brain morphometry
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Cardiometabolic risk factors, physical activity and psychiatric status in patients in long-term psychiatric inpatient departments
Nord J Psychiatry, 72 (4), 296-302
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Using motivational techniques to reduce cardiometabolic risk factors in long term psychiatric inpatients: a naturalistic interventional study
BMC Psychiatry, 18 (1), 255
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Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Nat Genet, 50 (7), 912-919
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Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts
BMJ, 360, j5757
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Thalamo-cortical functional connectivity in schizophrenia and bipolar disorder
Brain Imaging Behav, 12 (3), 640-652
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How can genetics help understand the relationship between cognitive dysfunction and schizophrenia?
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Genetic Overlap Between Schizophrenia and Volumes of Hippocampus, Putamen, and Intracranial Volume Indicates Shared Molecular Genetic Mechanisms
Schizophr Bull, 44 (4), 854-864
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Psychiatric genetics and the structure of psychopathology
Mol Psychiatry, 24 (3), 409-420
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Restriction spectrum imaging of white matter and its relation to neurological disability in multiple sclerosis
Mult Scler, 25 (5), 687-698
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Enrichment of genetic markers of recent human evolution in educational and cognitive traits
Sci Rep, 8 (1), 12585
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Genetic variation in 117 myelination-related genes in schizophrenia: Replication of association to lipid biosynthesis genes
Sci Rep, 8 (1), 6915
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Dose response of the 16p11.2 distal copy number variant on intracranial volume and basal ganglia
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Deep 2-photon imaging and artifact-free optogenetics through transparent graphene microelectrode arrays
Nat Commun, 9 (1), 2035
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Metacognitive Aspects of Executive Function Are Highly Associated with Social Functioning on Parent-Rated Measures in Children with Autism Spectrum Disorder
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White matter aberrations and age-related trajectories in patients with schizophrenia and bipolar disorder revealed by diffusion tensor imaging
Sci Rep, 8 (1), 14129
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Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes
Mol Psychiatry, 25 (11), 3053-3065
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Cortical Brain Abnormalities in 4474 Individuals With Schizophrenia and 5098 Control Subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) Consortium
Biol Psychiatry, 84 (9), 644-654
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Reply to: New Meta- and Mega-analyses of Magnetic Resonance Imaging Findings in Schizophrenia: Do They Really Increase Our Knowledge About the Nature of the Disease Process?
Biol Psychiatry, 85 (7), e35-e39
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Emotion perception, non-social cognition and symptoms as predictors of theory of mind in schizophrenia
Compr Psychiatry, 85, 1-7
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Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication
J Psychiatr Res, 106, 74-81
DOI 10.1016/j.jpsychires.2018.09.014, PubMed 30292780
Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?
J Psychiatr Res, 117, 150
DOI 10.1016/j.jpsychires.2018.11.012, PubMed 30454945
Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume
Nat Commun, 9 (1), 3945
DOI 10.1038/s41467-018-06234-w, PubMed 30258056
Meta-analysis of Alzheimer's disease on 9,751 samples from Norway and IGAP study identifies four risk loci
Sci Rep, 8 (1), 18088
DOI 10.1038/s41598-018-36429-6, PubMed 30591712
Mapping the Heterogeneous Phenotype of Schizophrenia and Bipolar Disorder Using Normative Models
JAMA Psychiatry, 75 (11), 1146-1155
DOI 10.1001/jamapsychiatry.2018.2467, PubMed 30304337
Longitudinal and cross-sectional investigations of long-term potentiation-like cortical plasticity in bipolar disorder type II and healthy individuals
Transl Psychiatry, 8 (1), 103
DOI 10.1038/s41398-018-0151-5, PubMed 29795193
Identification of shared genetic variants between schizophrenia and lung cancer
Sci Rep, 8 (1), 674
DOI 10.1038/s41598-017-16481-4, PubMed 29330379
Reduced brain-derived neurotrophic factor is associated with childhood trauma experiences and number of depressive episodes in severe mental disorders
Schizophr Res, 205, 45-50
DOI 10.1016/j.schres.2018.08.007, PubMed 30126813
Publications 2017
Diabetes and Schizophrenia-New Findings for an Old Puzzle
Am J Psychiatry, 174 (7), 616-617
DOI 10.1176/appi.ajp.2017.17040409, PubMed 28669214
eHealth provides a novel opportunity to exploit the advantages of the Nordic countries in psychiatric genetic research, building on the public health care system, biobanks, and registries
Am J Med Genet B Neuropsychiatr Genet, 177 (7), 625-629
DOI 10.1002/ajmg.b.32561, PubMed 28686333
Solar insolation in springtime influences age of onset of bipolar I disorder
Acta Psychiatr Scand, 136 (6), 571-582
DOI 10.1111/acps.12772, PubMed 28722128
Right unilateral electroconvulsive therapy does not cause more cognitive impairment than pharmacologic treatment in treatment-resistant bipolar depression: A 6-month randomized controlled trial follow-up study
Bipolar Disord, 20 (6), 531-538
DOI 10.1111/bdi.12594, PubMed 29267990
Leveraging genome characteristics to improve gene discovery for putamen subcortical brain structure
Sci Rep, 7 (1), 15736
DOI 10.1038/s41598-017-15705-x, PubMed 29147026
Genetic factors influencing prostate cancer risk in Norwegian men
Prostate, 78 (3), 186-192
DOI 10.1002/pros.23453, PubMed 29181843
Childhood Trauma and Minimization/Denial in People with and without a Severe Mental Disorder
Front Psychol, 8, 1276
DOI 10.3389/fpsyg.2017.01276, PubMed 28883800
Disrupted global metastability and static and dynamic brain connectivity across individuals in the Alzheimer's disease continuum
Sci Rep, 7, 40268
DOI 10.1038/srep40268, PubMed 28074926
Neurocognitive functioning, clinical course and functional outcome in first-treatment bipolar I disorder patients with and without clinical relapse: A 1-year follow-up study
Bipolar Disord, 20 (3), 228-237
DOI 10.1111/bdi.12569, PubMed 29121444
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score
PLoS Med, 14 (3), e1002258
DOI 10.1371/journal.pmed.1002258, PubMed 28323831
Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia
Mol Psychiatry, 22 (6), 792-801
DOI 10.1038/mp.2017.33, PubMed 28348379
Dissociable diffusion MRI patterns of white matter microstructure and connectivity in Alzheimer's disease spectrum
Sci Rep, 7, 45131
DOI 10.1038/srep45131, PubMed 28338052
Distinguishing early and late brain aging from the Alzheimer's disease spectrum: consistent morphological patterns across independent samples
Neuroimage, 158, 282-295
DOI 10.1016/j.neuroimage.2017.06.070, PubMed 28666881
Distinct multivariate brain morphological patterns and their added predictive value with cognitive and polygenic risk scores in mental disorders
Neuroimage Clin, 15, 719-731
DOI 10.1016/j.nicl.2017.06.014, PubMed 28702349
Increased sensitivity to age-related differences in brain functional connectivity during continuous multiple object tracking compared to resting-state
Neuroimage, 148, 364-372
DOI 10.1016/j.neuroimage.2017.01.048, PubMed 28111190
Body language reading of emotion in schizophrenia: Associations with symptoms and functional outcome
Scand J Psychol, 58 (5), 359-366
DOI 10.1111/sjop.12381, PubMed 28833180
Metabolic risk factors in schizophrenia and bipolar disorder: The effect of comedication with selective serotonin reuptake inhibitors and antipsychotics
Eur Psychiatry, 48, 71-78
DOI 10.1016/j.eurpsy.2017.04.001, PubMed 29331603
Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis
Schizophr Res, 197, 253-260
DOI 10.1016/j.schres.2017.10.042, PubMed 29129510
4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients
Br J Clin Pharmacol, 83 (11), 2398-2405
DOI 10.1111/bcp.13341, PubMed 28585378
Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex
Brain Imaging Behav, 11 (5), 1497-1514
DOI 10.1007/s11682-016-9629-z, PubMed 27738994
Biclustered Independent Component Analysis for Complex Biomarker and Subtype Identification from Structural Magnetic Resonance Images in Schizophrenia
Front Psychiatry, 8, 179
DOI 10.3389/fpsyt.2017.00179, PubMed 29018368
Ion diffusion may introduce spurious current sources in current-source density (CSD) analysis
J Neurophysiol, 118 (1), 114-120
DOI 10.1152/jn.00976.2016, PubMed 28298307
Cortical thickness, cortical surface area and subcortical volumes in schizophrenia and bipolar disorder patients with cannabis use
Eur Neuropsychopharmacol, 28 (1), 37-47
DOI 10.1016/j.euroneuro.2017.11.019, PubMed 29254657
Predicting Outcome 12 Months after Mild Traumatic Brain Injury in Patients Admitted to a Neurosurgery Service
Front Neurol, 8, 125
DOI 10.3389/fneur.2017.00125, PubMed 28443058
White matter microstructure is associated with functional, cognitive and emotional symptoms 12 months after mild traumatic brain injury
Sci Rep, 7 (1), 13795
DOI 10.1038/s41598-017-13628-1, PubMed 29061970
Longitudinal changes in brain morphology from 4 weeks to 12 months after mild traumatic brain injury: Associations with cognitive functions and clinical variables
Brain Inj, 31 (5), 674-685
DOI 10.1080/02699052.2017.1283537, PubMed 28414250
Novel genetic loci associated with hippocampal volume
Nat Commun, 8, 13624
DOI 10.1038/ncomms13624, PubMed 28098162
Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group
Mol Psychiatry, 23 (4), 932-942
DOI 10.1038/mp.2017.73, PubMed 28461699
A Study of TNF Pathway Activation in Schizophrenia and Bipolar Disorder in Plasma and Brain Tissue
Schizophr Bull, 43 (4), 881-890
DOI 10.1093/schbul/sbw183, PubMed 28049760
The relation between face-emotion recognition and social function in adolescents with autism spectrum disorders: A case control study
PLoS One, 12 (10), e0186124
DOI 10.1371/journal.pone.0186124, PubMed 29020059
Event-Related Potentials in a Cued Go-NoGo Task Associated with Executive Functions in Adolescents with Autism Spectrum Disorder; A Case-Control Study
Front Neurosci, 11, 393
DOI 10.3389/fnins.2017.00393, PubMed 28744191
Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy
Prog Neuropsychopharmacol Biol Psychiatry, 82, 263-271
DOI 10.1016/j.pnpbp.2017.11.004, PubMed 29122637
Parents' Attitudes toward Clinical Genetic Testing for Autism Spectrum Disorder-Data from a Norwegian Sample
Int J Mol Sci, 18 (5)
DOI 10.3390/ijms18051078, PubMed 28524073
Delayed stabilization and individualization in connectome development are related to psychiatric disorders
Nat Neurosci, 20 (4), 513-515
DOI 10.1038/nn.4511, PubMed 28218917
Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group
Mol Psychiatry, 23 (5), 1261-1269
DOI 10.1038/mp.2017.170, PubMed 29038599
Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets
Cell Rep, 21 (9), 2597-2613
DOI 10.1016/j.celrep.2017.11.028, PubMed 29186694
Identification of Gene Loci That Overlap Between Schizophrenia and Educational Attainment
Schizophr Bull, 43 (3), 654-664
DOI 10.1093/schbul/sbw085, PubMed 27338279
Modeling prior information of common genetic variants improves gene discovery for neuroticism
Hum Mol Genet, 26 (22), 4530-4539
DOI 10.1093/hmg/ddx340, PubMed 28973307
Genetic risk scores and family history as predictors of schizophrenia in Nordic registers
Psychol Med, 48 (7), 1201-1208
DOI 10.1017/S0033291717002665, PubMed 28942743
Combinations of genetic variants associated with bipolar disorder
PLoS One, 12 (12), e0189739
DOI 10.1371/journal.pone.0189739, PubMed 29267373
Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls
Mol Psychiatry, 23 (6), 1512-1520
DOI 10.1038/mp.2017.106, PubMed 28507318
A stepwise neuron model fitting procedure designed for recordings with high spatial resolution: Application to layer 5 pyramidal cells
J Neurosci Methods, 293, 264-283
DOI 10.1016/j.jneumeth.2017.10.007, PubMed 28993204
Pleiotropic effects of schizophrenia-associated genetic variants in neuron firing and cardiac pacemaking revealed by computational modeling
Transl Psychiatry, 7 (11), 5
DOI 10.1038/s41398-017-0007-4, PubMed 30446648
Persistent increase in TNF and IL-1 markers in severe mental disorders suggests trait-related inflammation: a one year follow-up study
Acta Psychiatr Scand, 136 (4), 400-408
DOI 10.1111/acps.12783, PubMed 28815548
Vitamin D Deficiency Associated With Cognitive Functioning in Psychotic Disorders
J Clin Psychiatry, 78 (7), e750-e757
DOI 10.4088/JCP.16m10880, PubMed 28493652
The quality of severe mental disorder diagnoses in a national health registry as compared to research diagnoses based on structured interview
BMC Psychiatry, 17 (1), 93
DOI 10.1186/s12888-017-1256-8, PubMed 28292279
Fourteen sequence variants that associate with multiple sclerosis discovered by meta-analysis informed by genetic correlations
NPJ Genom Med, 2, 24
DOI 10.1038/s41525-017-0027-2, PubMed 29263835
Analysis of the joint effect of SNPs to identify independent loci and allelic heterogeneity in schizophrenia GWAS data
Transl Psychiatry, 7 (12), 1289
DOI 10.1038/s41398-017-0033-2, PubMed 29249828
Oxytocin system dysfunction as a common mechanism underlying metabolic syndrome and psychiatric symptoms in schizophrenia and bipolar disorders
Front Neuroendocrinol, 45, 1-10
DOI 10.1016/j.yfrne.2016.12.004, PubMed 28049009
Diurnal Variation and Twenty-Four Hour Sleep Deprivation Do Not Alter Supine Heart Rate Variability in Healthy Male Young Adults
PLoS One, 12 (2), e0170921
DOI 10.1371/journal.pone.0170921, PubMed 28151944
Dose-dependent social-cognitive effects of intranasal oxytocin delivered with novel Breath Powered device in adults with autism spectrum disorder: a randomized placebo-controlled double-blind crossover trial
Transl Psychiatry, 7 (5), e1136
DOI 10.1038/tp.2017.103, PubMed 28534875
[Medication-free hospital records - a measure not based on knowledge]
Tidsskr Nor Laegeforen, 137 (6), 426-427
DOI 10.4045/tidsskr.17.0091, PubMed 28332789
[Not Available]
Tidsskr Nor Laegeforen, 137 (9), 594-595
DOI 10.4045/tidsskr.17.0288, PubMed 28468447
Novel Loci Associated With Attention-Deficit/Hyperactivity Disorder Are Revealed by Leveraging Polygenic Overlap With Educational Attainment
J Am Acad Child Adolesc Psychiatry, 57 (2), 86-95
DOI 10.1016/j.jaac.2017.11.013, PubMed 29413154
Consistent Functional Connectivity Alterations in Schizophrenia Spectrum Disorder: A Multisite Study
Schizophr Bull, 43 (4), 914-924
DOI 10.1093/schbul/sbw145, PubMed 27872268
Identification of Genetic Loci Jointly Influencing Schizophrenia Risk and the Cognitive Traits of Verbal-Numerical Reasoning, Reaction Time, and General Cognitive Function
JAMA Psychiatry, 74 (10), 1065-1075
DOI 10.1001/jamapsychiatry.2017.1986, PubMed 28746715
Identification of genetic loci shared between schizophrenia and the Big Five personality traits
Sci Rep, 7 (1), 2222
DOI 10.1038/s41598-017-02346-3, PubMed 28533504
Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study
CNS Drugs, 31 (11), 991-997
DOI 10.1007/s40263-017-0469-1, PubMed 28948574
Probing the Association between Early Evolutionary Markers and Schizophrenia
PLoS One, 12 (1), e0169227
DOI 10.1371/journal.pone.0169227, PubMed 28081145
Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis
Nat Genet, 49 (5), 801-805
DOI 10.1038/ng.3816, PubMed 28319091
Corrigendum: Whole-genome sequencing identifies rare genotypes in COMP and CHADL associated with high risk of hip osteoarthritis
Nat Genet, 49 (8), 1286
DOI 10.1038/ng0817-1286b, PubMed 28747754
Psychiatric Genomics: An Update and an Agenda
Am J Psychiatry, 175 (1), 15-27
DOI 10.1176/appi.ajp.2017.17030283, PubMed 28969442
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition
Acta Neuropathol, 135 (1), 85-93
DOI 10.1007/s00401-017-1789-4, PubMed 29177679
Polygenic hazard scores in preclinical Alzheimer disease
Ann Neurol, 82 (3), 484-488
DOI 10.1002/ana.25029, PubMed 28940650
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (3), 336-345
DOI 10.1038/mp.2016.244, PubMed 28093568
GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium
Mol Psychiatry, 22 (11), 1651-1652
DOI 10.1038/mp.2017.197, PubMed 29068436
The correlation between central and peripheral oxytocin concentrations: A systematic review and meta-analysis
Neurosci Biobehav Rev, 78, 117-124
DOI 10.1016/j.neubiorev.2017.04.017, PubMed 28442403
Impairment in emotion perception from body movements in individuals with bipolar I and bipolar II disorder is associated with functional capacity
Int J Bipolar Disord, 5 (1), 13
DOI 10.1186/s40345-017-0083-7, PubMed 28332121
Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium
Acta Psychiatr Scand, 135 (5), 439-447
DOI 10.1111/acps.12718, PubMed 28369804
Prefrontal cortical thinning links to negative symptoms in schizophrenia via the ENIGMA consortium
Psychol Med, 48 (1), 82-94
DOI 10.1017/S0033291717001283, PubMed 28545597
Shared genetic risk between migraine and coronary artery disease: A genome-wide analysis of common variants
PLoS One, 12 (9), e0185663
DOI 10.1371/journal.pone.0185663, PubMed 28957430
Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases
JAMA Neurol, 74 (7), 780-792
DOI 10.1001/jamaneurol.2017.0469, PubMed 28586827
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
Transl Psychiatry, 7 (6), e1155
DOI 10.1038/tp.2017.115, PubMed 28632202
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia
Acta Neuropathol, 133 (5), 825-837
DOI 10.1007/s00401-017-1693-y, PubMed 28271184
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer
BMC Genomics, 18 (1), 270
DOI 10.1186/s12864-017-3620-y, PubMed 28359301
Childhood maltreatment severity is associated with elevated C-reactive protein and body mass index in adults with schizophrenia and bipolar diagnoses
Brain Behav Immun, 65, 342-349
DOI 10.1016/j.bbi.2017.06.005, PubMed 28619247
Psychotic patients who used cannabis frequently before illness onset have higher genetic predisposition to schizophrenia than those who did not
Psychol Med, 48 (1), 43-49
DOI 10.1017/S0033291717001209, PubMed 28967348
Publications 2016
Novel genetic loci underlying human intracranial volume identified through genome-wide association
Nat Neurosci, 19 (12), 1569-1582
DOI 10.1038/nn.4398, PubMed 27694991
A genetic association study of CSMD1 and CSMD2 with cognitive function
Brain Behav Immun, 61, 209-216
DOI 10.1016/j.bbi.2016.11.026, PubMed 27890662
Modelling difficulties in abstract thinking in psychosis: the importance of socio-developmental background
Cogn Neuropsychiatry, 22 (1), 39-52
DOI 10.1080/13546805.2016.1259998, PubMed 28005457
Age-dependent effects of APOE ε4 in preclinical Alzheimer's disease
Ann Clin Transl Neurol, 3 (9), 668-77
DOI 10.1002/acn3.333, PubMed 27648456
Recovery from major depressive disorder episode after non-pharmacological treatment is associated with normalized cytokine levels
Acta Psychiatr Scand, 134 (1), 40-7
DOI 10.1111/acps.12576, PubMed 27028967
History of psychosis and previous episodes as potential explanatory factors for neurocognitive impairment in first-treatment bipolar I disorder
Bipolar Disord, 18 (2), 136-47
DOI 10.1111/bdi.12377, PubMed 26990158
Course of neurocognitive function in first treatment bipolar I disorder: One-year follow-up study
Psychiatry Res, 249, 286-292
DOI 10.1016/j.psychres.2016.12.048, PubMed 28142102
Somatic Comorbidity in Schizophrenia: Some Possible Biological Mechanisms Across the Life Span
Schizophr Bull, 42 (6), 1316-1319
DOI 10.1093/schbul/sbw028, PubMed 27033328
Age-related differences in brain network activation and co-activation during multiple object tracking
Brain Behav, 6 (11), e00533
DOI 10.1002/brb3.533, PubMed 27843692
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci
Nat Genet, 48 (5), 510-8
DOI 10.1038/ng.3528, PubMed 26974007
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases
J Neurol Neurosurg Psychiatry, 88 (2), 152-164
DOI 10.1136/jnnp-2016-314411, PubMed 27899424
Metabolic Abnormalities Related to Treatment With Selective Serotonin Reuptake Inhibitors in Patients With Schizophrenia or Bipolar Disorder
J Clin Psychopharmacol, 36 (6), 615-620
DOI 10.1097/JCP.0000000000000582, PubMed 27749681
Relationship of suicide rates with climate and economic variables in Europe during 2000-2012
Ann Gen Psychiatry, 15, 19
DOI 10.1186/s12991-016-0106-2, PubMed 27508001
Genetic influences on schizophrenia and subcortical brain volumes: large-scale proof of concept
Nat Neurosci, 19 (3), 420-431
DOI 10.1038/nn.4228, PubMed 26854805