Publications Experimental Drug Abuse Research

Publications 2024

Bergh MS, Bogen IL, Grafinger KE, Huestis MA, Øiestad ÅML (2024)
Metabolite markers for three synthetic tryptamines N-ethyl-N-propyltryptamine, 4-hydroxy-N-ethyl-N-propyltryptamine, and 5-methoxy-N-ethyl-N-propyltryptamine
Drug Test Anal (in press)
DOI 10.1002/dta.3668, PubMed 38459837

Bojarskaite L, Nafari S, Ravnanger AK, Frey MM, Skauli N, Åbjørsbråten KS, Roth LC, Amiry-Moghaddam M, Nagelhus EA, Ottersen OP, Bogen IL, Thoren AE, Enger R (2024)
Role of aquaporin-4 polarization in extracellular solute clearance
Fluids Barriers CNS, 21 (1), 28
DOI 10.1186/s12987-024-00527-7, PubMed 38532513

Heide G, Jamt REG, Fainberg-Sandbu J, Øiestad ÅML, Høiseth G (2024)
Driving under the influence of cocaine and MDMA: Relationship between blood concentrations and results from clinical test of impairment
J Anal Toxicol, 48 (5), 380-387
DOI 10.1093/jat/bkae024, PubMed 38613441

Mørland J, Innerdal CR, Markussen O, Vindenes V, Aamo TO, Slørdal L (2024)
[Not Available]
Tidsskr Nor Laegeforen, 144 (8)
DOI 10.4045/tidsskr.24.0160, PubMed 38934312

Noreng L, Wilson SR, Øiestad EL, Øiestad ML (2024)
On the Surprising Retention Order of Ketamine Analogs Using a Biphenyl Stationary Phase
LCGC Supplements Recent Developments in HPLC, 1, 26–29
DOI 10.56530/lcgc.int.yk4168j2, PublikaID 509

Nyberg H, Bogen IL, Nygaard E, Achterberg M, Andersen JM (2024)
Maternal exposure to buprenorphine, but not methadone, during pregnancy reduces social play behavior across two generations of offspring
Psychopharmacology (Berl) (in press)
DOI 10.1007/s00213-024-06718-2, PubMed 39633163

Nyberg H, Bogen IL, Nygaard E, Andersen JM (2024)
Effects of prenatal exposure to methadone or buprenorphine and maternal separation on anxiety-like behavior in rats
Drug Alcohol Depend, 262, 111367
DOI 10.1016/j.drugalcdep.2024.111367, PubMed 39003831

Schüller M, Bergh MS, Pedersen-Bjergaard S, Øiestad EL (2024)
Electromembrane extraction of drugs of abuse and prescription drugs from micropulverized hair
J Anal Toxicol, 48 (7), 489-498
DOI 10.1093/jat/bkae051, PubMed 38905017

Publications 2023

Bogen IL, Boix F, Andersen JM, Steinsland S, Nerem E, Mørland J (2023)
Heroin metabolism in human blood and its impact for the design of an immunotherapeutic approach against heroin effects
Basic Clin Pharmacol Toxicol, 133 (4), 418-427
DOI 10.1111/bcpt.13926, PubMed 37452619

Gjerde H, Bogstrand ST, Jamt REG, Vindenes V (2023)
Crash-involved THC-positive drivers in Norway have a high frequency of polysubstance use
Drug Alcohol Depend, 244, 109800
DOI 10.1016/j.drugalcdep.2023.109800, PubMed 36774807

Hansen JS, Boix F, Hasselstrøm JB, Sørensen LK, Kjolby M, Gustavsen S, Hansen RM, Petersen T, Sellebjerg F, Kasch H, Rasmussen PV, Finnerup NB, Saedder EA, Svendsen KB (2023)
Pharmacokinetics and pharmacodynamics of cannabis-based medicine in a patient population included in a randomized, placebo-controlled, clinical trial
Clin Transl Sci, 17 (1), e13685
DOI 10.1111/cts.13685, PubMed 38054364

Harrison SP, Siller R, Tanaka Y, Chollet ME, de la Morena-Barrio ME, Xiang Y, Patterson B, Andersen E, Bravo-Pérez C, Kempf H, Åsrud KS, Lunov O, Dejneka A, Mowinckel MC, Stavik B, Sandset PM, Melum E, Baumgarten S, Bonanini F, Kurek D, Mathapati S, Almaas R, Sharma K, Wilson SR, Skottvoll FS et al. (2023)
Scalable production of tissue-like vascularized liver organoids from human PSCs
Exp Mol Med, 55 (9), 2005-2024
DOI 10.1038/s12276-023-01074-1, PubMed 37653039

Rajalingam D, Boix F, Khoder A, Andersen JM, Paulsen RE (2023)
Distribution of morphine and methadone to the brain in a developmental chicken embryo model
Toxicol Appl Pharmacol, 479, 116731
DOI 10.1016/j.taap.2023.116731, PubMed 37866706

Schüller M, Lucic I, Øiestad ÅML, Pedersen-Bjergaard S, Øiestad EL (2023)
High-throughput quantification of emerging "nitazene" benzimidazole opioid analogs by microextraction and UHPLC-MS-MS
J Anal Toxicol, 47 (9), 787-796
DOI 10.1093/jat/bkad071, PubMed 37700512

Wilson T, Wisborg T, Vindenes V, Jamt REG, Bogstrand ST (2023)
Psychoactive substances and previous hospital admissions, triage and length of stay in rural injuries: a prospective observational study
Scand J Trauma Resusc Emerg Med, 31 (1), 86
DOI 10.1186/s13049-023-01156-z, PubMed 38012704

Øiestad EL, Øiestad ÅML, Middelkoop G, Brochmann GW, Thaulow CH, Vindenes V (2023)
Comparative Study of Postmortem Concentrations of Benzodiazepines and Z-Hypnotics in Several Different Matrices
J Anal Toxicol, 47 (3), 287-298
DOI 10.1093/jat/bkac106, PubMed 36542823

Publications 2022

D'Ottavio G, Reverte I, Ragozzino D, Meringolo M, Milella MS, Boix F, Venniro M, Badiani A, Caprioli D (2022)
Increased heroin intake and relapse vulnerability in intermittent relative to continuous self-administration: Sex differences in rats
Br J Pharmacol, 180 (7), 910-926
DOI 10.1111/bph.15791, PubMed 34986504

Edvardsen HME, Aamodt C, Bogstrand ST, Krajci P, Vindenes V, Rognli EB (2022)
Concentrations of psychoactive substances in blood samples from non-fatal and fatal opioid overdoses
Br J Clin Pharmacol, 88 (10), 4494-4504
DOI 10.1111/bcp.15365, PubMed 35470456

Havig SM, Vindenes V, Øiestad ÅML, Rogde S, Thaulow CH (2022)
Methadone, Buprenorphine, Oxycodone, Fentanyl and Tramadol in Multiple Postmortem Matrices
J Anal Toxicol, 46 (6), 600-610
DOI 10.1093/jat/bkab071, PubMed 34115841

Høiseth G, Vindenes V, Hilberg T, Bogstrand ST (2022)
[High level of ferritin and HDL cholesterol is associated with high alcohol consumption]
Tidsskr Nor Laegeforen, 142 (17)
DOI 10.4045/tidsskr.22.0431, PubMed 36416649

Jamt REG, Edvardsen HME, Middelkoop G, Kallevik AS, Bogstrand ST, Vevelstad MS, Vindenes V (2022)
Deaths associated with MDMA in the period 2000-2019
Tidsskr Nor Laegeforen, 142 (8)
DOI 10.4045/tidsskr.21.0547, PubMed 35635429

Kogler S, Aizenshtadt A, Harrison S, Skottvoll FS, Berg HE, Abadpour S, Scholz H, Sullivan G, Thiede B, Lundanes E, Bogen IL, Krauss S, Røberg-Larsen H, Wilson SR (2022)
"Organ-in-a-Column" Coupled On-line with Liquid Chromatography-Mass Spectrometry
Anal Chem, 94 (50), 17677-17684
DOI 10.1021/acs.analchem.2c04530, PubMed 36484723

Nyman AAT, Vindenes V, Strøm RT, Katadzic S, Gustavsen I, Bogstrand ST (2022)
Systematic screening of substance use upon hospitalisation
Tidsskr Nor Laegeforen, 142 (14)
DOI 10.4045/tidsskr.22.0481, PubMed 36226432

Vevelstad MS, Øiestad ÅML, Johansen U, von Krogh A, Torp HA (2022)
[Yew – a toxic shrub veiled in myth with medical potential]
Tidsskr Nor Laegeforen, 142 (6)
DOI 10.4045/tidsskr.22.0033, PubMed 35383451

von Linstow CU, Waider J, Bergh MS, Anzalone M, Madsen C, Nicolau AB, Wirenfeldt M, Lesch KP, Finsen B (2022)
The Combined Effects of Amyloidosis and Serotonin Deficiency by Tryptophan Hydroxylase-2 Knockout Impacts Viability of the APP/PS1 Mouse Model of Alzheimer's Disease
J Alzheimers Dis, 85 (3), 1283-1300
DOI 10.3233/JAD-210581, PubMed 34924373

Publications 2021

Andersen JM, Bogen IL, Karinen R, Brochmann GW, Mørland J, Vindenes V, Boix F (2021)
Does the preparation for intravenous administration affect the composition of heroin injections? A controlled laboratory study
Addiction, 116 (11), 3104-3112
DOI 10.1111/add.15492, PubMed 33739552

Bergh MS, Bogen IL, Garibay N, Baumann MH (2021)
Pharmacokinetics and pharmacodynamics of cyclopropylfentanyl in male rats
Psychopharmacology (Berl), 238 (12), 3629-3641
DOI 10.1007/s00213-021-05981-x, PubMed 34613431

Bergh MSS, Bogen IL, Nerem E, Wohlfarth A, Wilson SR, Oiestad AML (2021)
Discovering the major metabolites of the three novel fentanyl analogues 3-methylcrotonylfentanyl, furanylbenzylfentanyl, and 4-fluorocyclopropylbenzylfentanyl for forensic case work
Forensic Toxicol., 39 (1), 167-178
DOI 10.1007/s11419-020-00560-9

Boix F (2021)
[Is the conclusion reliable?]
Tidsskr Nor Laegeforen, 141 (7)
DOI 10.4045/tidsskr.21.0306, PubMed 33950652

Gjerde H, Bretteville-Jensen AL, Bache-Andreassen L, Hanoa K, Furuhaugen H, Brochmann GW, Vindenes V (2021)
Which illicit drugs are injected in Oslo? A study based on analysis of drug residues in used injection equipment and self-reported information
Scand J Public Health, 51 (1), 21-27
DOI 10.1177/14034948211043984, PubMed 34538164

Høiseth G, Hilberg T, Trydal T, Husa A, Vindenes V, Bogstrand ST (2021)
The alcohol marker phosphatidylethanol is closely related to AST, GGT, ferritin and HDL-C
Basic Clin Pharmacol Toxicol, 130 (1), 182-190
DOI 10.1111/bcpt.13662, PubMed 34591374

Jørgenrud B, Kabashi S, Nadezhdin A, Bryun E, Koshkina E, Tetenova E, Lerdal A, Norby G, Kolgashkin A, Petukhov A, Perekhodov S, Davydova E, Vindenes V, Gamboa D, Bogstrand ST (2021)
The Association between the Alcohol Biomarker Phosphatidylethanol (PEth) and Self-Reported Alcohol Consumption among Russian and Norwegian Medical Patients
Alcohol Alcohol, 56 (6), 726-736
DOI 10.1093/alcalc/agab013, PubMed 33677484

Kabashi S, Gamboa D, Vindenes V, Berg T, Hilberg TA, Jørgenrud B, Lerdal A, Bogstrand ST (2021)
Multimorbidity, psychoactive substance use and psychological distress among acute medically ill patients: a cross-sectional study
BMJ Open, 11 (11), e052428
DOI 10.1136/bmjopen-2021-052428, PubMed 34815283

Mygind L, Bergh MS, Tejsi V, Vaitheeswaran R, Lambertsen KL, Finsen B, Metaxas A (2021)
Tumor Necrosis Factor (TNF) Is Required for Spatial Learning and Memory in Male Mice under Physiological, but Not Immune-Challenged Conditions
Cells, 10 (3)
DOI 10.3390/cells10030608, PubMed 33803476

Pettersen S, Øiestad ÅML, Rogde S, Brochmann GW, Øiestad EL, Vindenes V (2021)
Distribution of tetrahydrocannabinol and cannabidiol in several different postmortem matrices
Forensic Sci Int, 329, 111082
DOI 10.1016/j.forsciint.2021.111082, PubMed 34775328

Skottvoll FS, Hansen FA, Harrison S, Boger IS, Mrsa A, Restan MS, Stein M, Lundanes E, Pedersen-Bjergaard S, Aizenshtadt A, Krauss S, Sullivan G, Bogen IL, Wilson SR (2021)
Electromembrane Extraction and Mass Spectrometry for Liver Organoid Drug Metabolism Studies
Anal Chem, 93 (7), 3576-3585
DOI 10.1021/acs.analchem.0c05082, PubMed 33534551

Tuv SS, Bergh MS, Andersen JM, Steinsland S, Vindenes V, Baumann MH, Huestis MA, Bogen IL (2021)
Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents
Int J Mol Sci, 22 (21)
DOI 10.3390/ijms222112002, PubMed 34769427

Wilson T, Wisborg T, Vindenes V, Jamt RG, Furuhaugen H, Bogstrand ST (2021)
Psychoactive substances have major impact on injuries in rural arctic Norway - A prospective observational study
Acta Anaesthesiol Scand, 65 (6), 824-833
DOI 10.1111/aas.13807, PubMed 33638866

Yadav A, Verhaegen S, Hadera MG, Berntsen HF, Berg V, Lyche JL, Sabaredzovic A, Haug LS, Myhre O, Zimmer KE, Paulsen RE, Ropstad E, Boix F (2021)
Peripherally administered persistent organic pollutants distribute to the brain of developing chicken embryo in concentrations relevant for human exposure
Neurotoxicology, 88, 79-87
DOI 10.1016/j.neuro.2021.10.013, PubMed 34757084

Zosen D, Hadera MG, Lumor JS, Andersen JM, Paulsen RE (2021)
Chicken embryo as animal model to study drug distribution to the developing brain
J Pharmacol Toxicol Methods, 112, 107105
DOI 10.1016/j.vascn.2021.107105, PubMed 34284116

Publications 2020

Andersen JM, Høiseth G, Nygaard E (2020)
Prenatal exposure to methadone or buprenorphine and long-term outcomes: A meta-analysis
Early Hum Dev, 143, 104997
DOI 10.1016/j.earlhumdev.2020.104997, PubMed 32146140

Andersen JM, Opdal SH, Müller CP, Boix F (2020)
CaMKII is activated in opioid induced conditioned place preference, but αCaMKII Thr286 autophosphorylation is not necessary for its establishment
Behav Brain Res, 390, 112676
DOI 10.1016/j.bbr.2020.112676, PubMed 32407818

Bech AB, Clausen T, Waal H, Vindenes V, Edvardsen HE, Frost J, Skeie I (2020)
Post-mortem toxicological analyses of blood samples from 107 patients receiving opioid agonist treatment: substances detected and pooled opioid and benzodiazepine concentrations
Addiction, 116 (4), 845-855
DOI 10.1111/add.15211, PubMed 32738014

Bergh MS, Øiestad ÅML, Baumann MH, Bogen IL (2020)
Selectivity and sensitivity of urine fentanyl test strips to detect fentanyl analogues in illicit drugs
Int J Drug Policy, 90, 103065
DOI 10.1016/j.drugpo.2020.103065, PubMed 33333419

Gamboa D, Jørgenrud B, Bryun EA, Vindenes V, Koshkina EA, Nadezhdin AV, Kabashi S, Tetenova EJ, Berg T, Nyman AAT, Kolgashkin AJ, Petukhov AE, Perekhodov SN, Davydova EN, Lerdal A, Nordby G, Bogstrand ST (2020)
Prevalence of psychoactive substance use among acutely hospitalised patients in Oslo and Moscow: a cross-sectional, observational study
BMJ Open, 10 (9), e032572
DOI 10.1136/bmjopen-2019-032572, PubMed 32948540

Gjerde H, Bretteville-Jensen AL, Furuhaugen H, Bache-Andreassen L, Bergh MS, Vindenes V (2020)
Determination of drug residues in used syringe needles
Drug Test Anal, 12 (3), 410-416
DOI 10.1002/dta.2759, PubMed 31899604

Heide G, Høiseth G, Middelkoop G, Øiestad ÅML (2020)
Blood Concentrations of Designer Benzodiazepines: Relation to Impairment and Findings in Forensic Cases
J Anal Toxicol, 44 (8), 905-914
DOI 10.1093/jat/bkaa043, PubMed 32369173

Jamt REG, Gjerde H, Furuhaugen H, Romeo G, Vindenes V, Ramaekers JG, Bogstrand ST (2020)
Associations between psychoactive substance use and sensation seeking behavior among drivers in Norway
BMC Public Health, 20 (1), 23
DOI 10.1186/s12889-019-8087-0, PubMed 31914964

Kabashi S, Vindenes V, Bryun EA, Koshkina EA, Nadezhdin AV, Tetenova EJ, Kolgashkin AJ, Petukhov AE, Perekhodov SN, Davydova EN, Gamboa D, Hilberg T, Lerdal A, Nordby G, Zhang C, Bogstrand ST (2020)
Corrigendum to "Harmful alcohol use among acutely ill hospitalized medical patients in Oslo and Moscow: A cross-sectional study" [Drug Alcohol Depend. 204 (2019) 107588]
Drug Alcohol Depend, 213, 108073
DOI 10.1016/j.drugalcdep.2020.108073, PubMed 32570137

Kongstorp M, Bogen IL, Steinsland S, Nerem E, Salih TW, Stiris T, Andersen JM (2020)
Prenatal exposure to methadone or buprenorphine alters µ-opioid receptor binding and downstream signaling in the rat brain
Int J Dev Neurosci, 80 (5), 443-453
DOI 10.1002/jdn.10043, PubMed 32484968

Kongstorp M, Bogen IL, Stiris T, Andersen JM (2020)
Prenatal exposure to methadone or buprenorphine impairs cognitive performance in young adult rats
Drug Alcohol Depend, 212, 108008
DOI 10.1016/j.drugalcdep.2020.108008, PubMed 32402939

Rhein C, Mühle C, Lenz B, Richter-Schmidinger T, Kogias G, Boix F, Lourdusamy A, Dörfler A, Peters O, Ramirez A, Jessen F, Maier W, Hüll M, Frölich L, Teipel S, Wiltfang J, Kornhuber J, Müller CP (2020)
Association of a CAMK2A genetic variant with logical memory performance and hippocampal volume in the elderly
Brain Res Bull, 161, 13-20
DOI 10.1016/j.brainresbull.2020.05.001, PubMed 32418901

Seljetun KO, Sandvik M, Vindenes V, Eliassen E, Øiestad EL, Madslien K, Moe L (2020)
Comparison of anticoagulant rodenticide concentrations in liver and feces from apparently healthy red foxes
J Vet Diagn Invest, 32 (4), 560-564
DOI 10.1177/1040638720927365, PubMed 32476615

Seljetun KO, Vindenes V, Øiestad EL, Brochmann GW, Eliassen E, Moe L (2020)
Determination of anticoagulant rodenticides in faeces of exposed dogs and in a healthy dog population
Acta Vet Scand, 62 (1), 30
DOI 10.1186/s13028-020-00531-5, PubMed 32546243

Årving A, Høiseth G, Hilberg T, Trydal T, Husa A, Djordjevic A, Kabashi S, Vindenes V, Bogstrand ST (2020)
Comparison of the Diagnostic Value of Phosphatidylethanol and Carbohydrate-Deficient Transferrin as Biomarkers of Alcohol Consumption
Alcohol Clin Exp Res, 45 (1), 153-162
DOI 10.1111/acer.14503, PubMed 33164220

Publications 2019

Bergh MS, Bogen IL, Garibay N, Baumann MH (2019)
Evidence for nonlinear accumulation of the ultrapotent fentanyl analog, carfentanil, after systemic administration to male rats
Neuropharmacology, 158, 107596
DOI 10.1016/j.neuropharm.2019.04.002, PubMed 30965021

Bergh MS, Bogen IL, Wohlfarth A, Wilson SR, Øiestad ÅML (2019)
Distinguishing Between Cyclopropylfentanyl and Crotonylfentanyl by Methods Commonly Available in the Forensic Laboratory
Ther Drug Monit, 41 (4), 519-527
DOI 10.1097/FTD.0000000000000617, PubMed 30807539

Bramness JG, Vindenes V (2019)
[Medical cannabis]
Tidsskr Nor Laegeforen, 139 (15)
DOI 10.4045/tidsskr.19.0595, PubMed 31642634

Bramness JG, Vindenes V (2019)
Medical cannabis
Tidsskr. Nor. Laegeforen., 139 (15), 1437

Fjelldal MF, Hadera MG, Kongstorp M, Austdal LPE, Šulović A, Andersen JM, Paulsen RE (2019)
Opioid receptor-mediated changes in the NMDA receptor in developing rat and chicken
Int J Dev Neurosci, 78, 19-27
DOI 10.1016/j.ijdevneu.2019.07.009, PubMed 31351113

Kabashi S, Vindenes V, Bryun EA, Koshkina EA, Nadezhdin AV, Tetenova EJ, Kolgashkin AJ, Petukhov AE, Perekhodov SN, Davydova EN, Gamboa D, Hilberg T, Lerdal A, Nordby G, Zhang C, Bogstrand ST (2019)
Harmful alcohol use among acutely ill hospitalized medical patients in Oslo and Moscow: A cross-sectional study
Drug Alcohol Depend, 204, 107588
DOI 10.1016/j.drugalcdep.2019.107588, PubMed 31590131

Kongstorp M, Bogen IL, Stiris T, Andersen JM (2019)
High Accumulation of Methadone Compared with Buprenorphine in Fetal Rat Brain after Maternal Exposure
J Pharmacol Exp Ther, 371 (1), 130-137
DOI 10.1124/jpet.119.259531, PubMed 31358559

Kvello AMS, Andersen JM, Boix F, Mørland J, Bogen IL (2019)
The role of 6-acetylmorphine in heroin-induced reward and locomotor sensitization in mice
Addict Biol, 25 (2), e12727
DOI 10.1111/adb.12727, PubMed 30788879

Oiestad EL, Krabseth HM, Huestis MA, Skulberg A, Vindenes V (2019)
Interpreting oral fluid drug results in prisoners: monitoring current drug intake and detection times for drugs self-administered prior to detention
Forensic Toxicol., 37 (1), 59-74
DOI 10.1007/s11419-018-0434-9

Seljetun KO, Eliassen E, Madslien K, Viljugrein H, Vindenes V, Øiestad EL, Moe L (2019)
PREVALENCE OF ANTICOAGULANT RODENTICIDES IN FECES OF WILD RED FOXES (VULPES VULPES) IN NORWAY
J Wildl Dis, 55 (4), 834-843
DOI 10.7589/2019-01-027, PubMed 31112468

Strand MC, Ramaekers JG, Gjerde H, Mørland J, Vindenes V (2019)
Pharmacokinetics of Single Doses of Methadone and Buprenorphine in Blood and Oral Fluid in Healthy Volunteers and Correlation With Effects on Psychomotor and Cognitive Functions
J Clin Psychopharmacol, 39 (5), 489-493
DOI 10.1097/JCP.0000000000001077, PubMed 31305338

Valen A, Bogstrand ST, Vindenes V, Frost J, Larsson M, Holtan A, Gjerde H (2019)
Fatally injured drivers in Norway 2005-2015-Trends in substance use and crash characteristics
Traffic Inj Prev, 20 (5), 460-466
DOI 10.1080/15389588.2019.1616700, PubMed 31169405

Valen A, Bogstrand ST, Vindenes V, Frost J, Larsson M, Holtan A, Gjerde H (2019)
Driver-related risk factors of fatal road traffic crashes associated with alcohol or drug impairment
Accid Anal Prev, 131, 191-199
DOI 10.1016/j.aap.2019.06.014, PubMed 31306833

Publications 2018

Avvisati R, Bogen IL, Andersen JM, Vindenes V, Mørland J, Badiani A, Boix F (2018)
The active heroin metabolite 6-acetylmorphine has robust reinforcing effects as assessed by self-administration in the rat
Neuropharmacology, 150, 192-199
DOI 10.1016/j.neuropharm.2018.12.023, PubMed 30578794

Bergh MS, Bogen IL, Wilson SR, Øiestad ÅML (2018)
Addressing the Fentanyl Analogue Epidemic by Multiplex UHPLC-MS/MS Analysis of Whole Blood
Ther Drug Monit, 40 (6), 738-748
DOI 10.1097/FTD.0000000000000564, PubMed 30157097

Furuhaugen H, Jamt REG, Nilsson G, Vindenes V, Gjerde H (2018)
Roadside survey of alcohol and drug use among Norwegian drivers in 2016-2017: A follow-up of the 2008-2009 survey
Traffic Inj Prev, 19 (6), 555-562
DOI 10.1080/15389588.2018.1478087, PubMed 29927625

Høiseth G, Arnestad M, Karinen R, Morini L, Rogde S, Sempio C, Vindenes V, Øiestad ÅML (2018)
Is Hair Analysis Useful in Postmortem Cases?
J Anal Toxicol, 42 (1), 49-54
DOI 10.1093/jat/bkx077, PubMed 28977558

Jørgenrud B, Bogstrand ST, Furuhaugen H, Jamt REG, Vindenes V, Gjerde H (2018)
Association between speeding and use of alcohol and medicinal and illegal drugs and involvement in road traffic crashes among motor vehicle drivers
Traffic Inj Prev, 19 (8), 779-785
DOI 10.1080/15389588.2018.1518577, PubMed 30681887

Kvello AMS, Andersen JM, Øiestad EL, Steinsland S, Aase A, Mørland J, Bogen IL (2018)
A Monoclonal Antibody against 6-Acetylmorphine Protects Female Mice Offspring from Adverse Behavioral Effects Induced by Prenatal Heroin Exposure
J Pharmacol Exp Ther, 368 (1), 106-115
DOI 10.1124/jpet.118.251504, PubMed 30361238

Løseth GE, Eikemo M, Isager P, Holmgren J, Laeng B, Vindenes V, Hjørnevik T, Leknes S (2018)
Morphine reduced perceived anger from neutral and implicit emotional expressions
Psychoneuroendocrinology, 91, 123-131
DOI 10.1016/j.psyneuen.2018.02.035, PubMed 29550675

Mardal M, Johansen SS, Davidsen AB, Telving R, Jornil JR, Dalsgaard PW, Hasselstrøm JB, Øiestad ÅM, Linnet K, Andreasen MF (2018)
Postmortem analysis of three methoxyacetylfentanyl-related deaths in Denmark and in vitro metabolite profiling in pooled human hepatocytes
Forensic Sci Int, 290, 310-317
DOI 10.1016/j.forsciint.2018.07.020, PubMed 30107329

Oiestad AML, Berg T, Eliassen E, Wiklund T, Sand K, Oiestad EL (2018)
Separation of isomers of new psychoactive substances and isotope-labeled amphetamines using UHPSFC-MS/MS and UHPLC-MS/MS
J. Liq. Chromatogr. Relat. Technol., 41 (7), 391-400
DOI 10.1080/10826076.2017.1388818

Seljetun KO, Eliassen E, Karinen R, Moe L, Vindenes V (2018)
Quantitative method for analysis of six anticoagulant rodenticides in faeces, applied in a case with repeated samples from a dog
Acta Vet Scand, 60 (1), 3
DOI 10.1186/s13028-018-0357-9, PubMed 29343296

Strand MC, Vindenes V, Gjerde H, Mørland JG, Ramaekers JG (2018)
A clinical trial on the acute effects of methadone and buprenorphine on actual driving and cognitive function of healthy volunteers
Br J Clin Pharmacol, 85 (2), 442-453
DOI 10.1111/bcp.13818, PubMed 30515857

Takitane J, Leyton V, Andreuccetti G, Gjerde H, Vindenes V, Berg T (2018)
Determination of cocaine, metabolites and a crack cocaine biomarker in whole blood by liquid-liquid extraction and UHPLC-MS/MS
Forensic Sci Int, 289, 165-174
DOI 10.1016/j.forsciint.2018.05.030, PubMed 29885489

Thaulow CH, Øiestad ÅML, Rogde S, Andersen JM, Høiseth G, Handal M, Mørland J, Vindenes V (2018)
Can measurements of heroin metabolites in post-mortem matrices other than peripheral blood indicate if death was rapid or delayed?
Forensic Sci Int, 290, 121-128
DOI 10.1016/j.forsciint.2018.06.041, PubMed 30015276

Thaulow CH, Øiestad ÅML, Rogde S, Karinen R, Brochmann GW, Andersen JM, Høiseth G, Handal M, Mørland J, Arnestad M, Øiestad EL, Strand DH, Vindenes V (2018)
Metabolites of Heroin in Several Different Post-mortem Matrices
J Anal Toxicol, 42 (5), 311-320
DOI 10.1093/jat/bky002, PubMed 29409037

Vårdal L, Wong G, Øiestad ÅML, Pedersen-Bjergaard S, Gjelstad A, Øiestad EL (2018)
Rapid determination of designer benzodiazepines, benzodiazepines, and Z-hypnotics in whole blood using parallel artificial liquid membrane extraction and UHPLC-MS/MS
Anal Bioanal Chem, 410 (20), 4967-4978
DOI 10.1007/s00216-018-1147-y, PubMed 29947895

Øiestad ÅML, Karinen R, Rogde S, Nilsen S, Boye Eldor KB, Brochmann GW, Arnestad M, Øiestad EL, Peres MD, Kristoffersen L, Vindenes V (2018)
Comparative Study of Postmortem Concentrations of Antidepressants in Several Different Matrices
J Anal Toxicol, 42 (7), 446-458
DOI 10.1093/jat/bky030, PubMed 29762694

Publications 2017

Bergh MS, Bogen IL, Andersen JM, Øiestad ÅML, Berg T (2017)
Determination of adrenaline, noradrenaline and corticosterone in rodent blood by ion pair reversed phase UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1072, 161-172
DOI 10.1016/j.jchromb.2017.11.016, PubMed 29175696

Berntsen HF, Bogen IL, Wigestrand MB, Fonnum F, Walaas SI, Moldes-Anaya A (2017)
The fungal neurotoxin penitrem A induces the production of reactive oxygen species in human neutrophils at submicromolar concentrations
Toxicology, 392, 64-70
DOI 10.1016/j.tox.2017.10.008, PubMed 29037868

Edvardsen HE, Tverborgvik T, Frost J, Rogde S, Morild I, Waal H, Clausen T, Slørdal L, Vindenes V (2017)
Differences in combinations and concentrations of drugs of abuse in fatal intoxication and driving under the influence cases
Forensic Sci Int, 281, 127-133
DOI 10.1016/j.forsciint.2017.10.045, PubMed 29128652

Edvardsen HE, Tverborgvik T, Frost J, Rogde S, Morild I, Waal H, Clausen T, Slørdal L, Vindenes V (2017)
Corrigendum to "Differences in combinations and concentrations of drugs of abuse in fatal intoxication and driving under the influence cases" [Forensic Sci. Int. 281 (2017) 127-133]
Forensic Sci Int, 283, 219
DOI 10.1016/j.forsciint.2017.12.040, PubMed 29324351

Havig SM, Høiseth G, Strand MC, Karinen RA, Brochmann GW, Strand DH, Bachs L, Vindenes V (2017)
THC and CBD in blood samples and seizures in Norway: Does CBD affect THC-induced impairment in apprehended subjects?
Forensic Sci Int, 276, 12-17
DOI 10.1016/j.forsciint.2017.04.006, PubMed 28463706

Hjelmeland K, Gustavsen I, Øiestad EL, Øiestad ÅML, Høiseth G, Mørland J (2017)
Zopiclone concentrations in oral fluid and blood after, administration of therapeutic doses of zopiclone
Forensic Sci Int, 278, 177-183
DOI 10.1016/j.forsciint.2017.07.004, PubMed 28735217

Hofer T, Duale N, Muusse M, Eide DM, Dahl H, Boix F, Andersen JM, Olsen AK, Myhre O (2017)
Restoration of Cognitive Performance in Mice Carrying a Deficient Allele of 8-Oxoguanine DNA Glycosylase by X-ray Irradiation
Neurotox Res, 33 (4), 824-836
DOI 10.1007/s12640-017-9833-7, PubMed 29101721

Strand MC, Mørland J, Slørdal L, Riedel B, Innerdal C, Aamo T, Mathisrud G, Vindenes V (2017)
Conversion factors for assessment of driving impairment after exposure to multiple benzodiazepines/z-hypnotics or opioids
Forensic Sci Int, 281, 29-36
DOI 10.1016/j.forsciint.2017.10.022, PubMed 29101905

Valen A, Bogstrand ST, Vindenes V, Gjerde H (2017)
Increasing use of cannabis among arrested drivers in Norway
Traffic Inj Prev, 18 (8), 801-806
DOI 10.1080/15389588.2017.1321114, PubMed 28448164

Valen A, Bogstrand ST, Vindenes V, Gjerde H (2017)
Toxicological findings in suspected drug-impaired drivers in Norway - Trends during 1990-2015
Forensic Sci Int, 280, 15-24
DOI 10.1016/j.forsciint.2017.09.010, PubMed 28942374

Vevelstad M, Øiestad EL, Nerem E, Arnestad M, Bogen IL (2017)
Studies on Para-Methoxymethamphetamine (PMMA) Metabolite Pattern and Influence of CYP2D6 Genetics in Human Liver Microsomes and Authentic Samples from Fatal PMMA Intoxications
Drug Metab Dispos, 45 (12), 1326-1335
DOI 10.1124/dmd.117.077263, PubMed 28978661

Publications 2016

Andås HT, Enger A, Øiestad ÅM, Vindenes V, Christophersen AS, Huestis MA, Øiestad EL (2016)
Extended Detection of Amphetamine and Methamphetamine in Oral Fluid
Ther Drug Monit, 38 (1), 114-9
DOI 10.1097/FTD.0000000000000248, PubMed 26402425

Bergh MS, Bogen IL, Lundanes E, Øiestad ÅML (2016)
Validated methods for determination of neurotransmitters and metabolites in rodent brain tissue and extracellular fluid by reversed phase UHPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 1028, 120-129
DOI 10.1016/j.jchromb.2016.06.011, PubMed 27336704

Berntsen HF, Fonnum F, Walaas SI, Bogen IL (2016)
Low-Chlorinated Non-Dioxin-like Polychlorinated Biphenyls Present in Blood and Breast Milk Induce Higher Levels of Reactive Oxygen Species in Neutrophil Granulocytes than High-Chlorinated Congeners
Basic Clin Pharmacol Toxicol, 119 (6), 588-597
DOI 10.1111/bcpt.12620, PubMed 27194217

Eriksen GS, Andersen JM, Boix F, Bergh MS, Vindenes V, Rice KC, Huestis MA, Mørland J (2016)
Comparison of (+)- and (-)-Naloxone on the Acute Psychomotor-Stimulating Effects of Heroin, 6-Acetylmorphine, and Morphine in Mice
J Pharmacol Exp Ther, 358 (2), 209-15
DOI 10.1124/jpet.116.233544, PubMed 27278234

Høiseth G, Berg-Hansen GO, Øiestad ÅM, Bachs L, Mørland J (2016)
Impairment due to alcohol, tetrahydrocannabinol, and benzodiazepines in impaired drivers compared to experimental studies
Traffic Inj Prev, 18 (3), 244-250
DOI 10.1080/15389588.2016.1201205, PubMed 27327554

Krabseth HM, Tuv SS, Strand MC, Karinen RA, Wiik E, Vevelstad MS, Westin AA, Oiestad EL, Vindenes V (2016)
New psychoactive substances
Tidsskr. Nor. Laegeforen., 136 (8), 714-717

Krabseth HM, Tuv SS, Strand MC, Karinen RA, Wiik E, Vevelstad MS, Westin AA, Øiestad EL, Vindenes V (2016)
Novel psychoactive substances
Tidsskr Nor Laegeforen, 136 (8), 714-7
DOI 10.4045/tidsskr.15.1278, PubMed 27143461

Kvello AM, Andersen JM, Øiestad EL, Mørland J, Bogen IL (2016)
Pharmacological Effects of a Monoclonal Antibody against 6-Monoacetylmorphine upon Heroin-Induced Locomotor Activity and Pharmacokinetics in Mice
J Pharmacol Exp Ther, 358 (2), 181-9
DOI 10.1124/jpet.116.233510, PubMed 27217591

Strand MC, Innerdal C, Mathisrud G, Mørland J, Riedel B, Slørdal L, Aamo TO, Vindenes V (2016)
[Revision of fixed limits for drugs in the traffic]
Tidsskr Nor Laegeforen, 136 (19), 1619-1620
DOI 10.4045/tidsskr.16.0730, PubMed 27790887

Tuv SS, Krabseth HM, Strand MC, Karinen RA, Wiik E, Vevelstad MS, Westin AA, Oiestad EL, Vindenes V (2016)
New drugs right from the online
Tidsskr. Nor. Laegeforen., 136 (8), 721-723

Tuv SS, Krabseth HM, Strand MC, Karinen RA, Wiik E, Vevelstad MS, Westin AA, Øiestad EL, Vindenes V (2016)
New designer drugs from the web
Tidsskr Nor Laegeforen, 136 (8), 721-3
DOI 10.4045/tidsskr.15.1276, PubMed 27143463

Valen A, Leere Øiestad ÅM, Strand DH, Skari R, Berg T (2016)
Determination of 21 drugs in oral fluid using fully automated supported liquid extraction and UHPLC-MS/MS
Drug Test Anal, 9 (5), 808-823
DOI 10.1002/dta.2045, PubMed 27464485

Vevelstad M, Øiestad EL, Bremer S, Bogen IL, Zackrisson AL, Arnestad M (2016)
Is toxicity of PMMA (paramethoxymethamphetamine) associated with cytochrome P450 pharmacogenetics?
Forensic Sci Int, 261, 137-47
DOI 10.1016/j.forsciint.2016.02.027, PubMed 26930544

Vindenes V, Bramness JG, Bretteville-Jensen AL, Mørland J, Bachs L (2016)
[Does stronger cannabis cause more health problems?]
Tidsskr Nor Laegeforen, 136 (20), 1736-1738
DOI 10.4045/tidsskr.15.1297, PubMed 27830910

Vindenes V, Strand DH, Koksæter P, Gjerde H (2016)
Detection of Nitrobenzodiazepines and Their 7-Amino Metabolites in Oral Fluid
J Anal Toxicol, 40 (4), 310-2
DOI 10.1093/jat/bkw020, PubMed 27013620

Øiestad EL, Øiestad ÅM, Gjelstad A, Karinen R (2016)
Oral fluid drug analysis in the age of new psychoactive substances
Bioanalysis, 8 (7), 691-710
DOI 10.4155/bio-2015-0027, PubMed 26964619

Publications 2015

Austdal LE, Strand MC, Vindenes V, Bogstrand ST (2015)
[Prevalence of injuries associated with the «russ» celebration in Norway]
Tidsskr Nor Laegeforen, 135 (7), 648-52
DOI 10.4045/tidsskr.14.0238, PubMed 25899369

Bogstrand ST, Larsson M, Holtan A, Staff T, Vindenes V, Gjerde H (2015)
Associations between driving under the influence of alcohol or drugs, speeding and seatbelt use among fatally injured car drivers in Norway
Accid Anal Prev, 78, 14-19
DOI 10.1016/j.aap.2014.12.025, PubMed 25725424

Gottås A, Ripel Å, Boix F, Vindenes V, Mørland J, Øiestad EL (2015)
Determination of dopamine concentrations in brain extracellular fluid using microdialysis with short sampling intervals, analyzed by ultra high performance liquid chromatography tandem mass spectrometry
J Pharmacol Toxicol Methods, 74, 75-9
DOI 10.1016/j.vascn.2015.06.002, PubMed 26123500

Karinen R, Høiseth G, Svendsen KO, Rogde S, Vindenes V (2015)
A fatal intoxication with phenazone (antipyrine)
Forensic Sci Int, 248, e13-5
DOI 10.1016/j.forsciint.2015.01.001, PubMed 25631541

Kristoffersen L, Strand DH, Liane VH, Vindenes V, Tvete IF, Aldrin M (2015)
Determination of safety margins for whole blood concentrations of alcohol and nineteen drugs in driving under the influence cases
Forensic Sci Int, 259, 119-26
DOI 10.1016/j.forsciint.2015.12.009, PubMed 26773222

Nordal K, Øiestad EL, Enger A, Christophersen AS, Vindenes V (2015)
Detection Times of Diazepam, Clonazepam, and Alprazolam in Oral Fluid Collected From Patients Admitted to Detoxification, After High and Repeated Drug Intake
Ther Drug Monit, 37 (4), 451-60
DOI 10.1097/FTD.0000000000000174, PubMed 25549207

Simonsen KW, Edvardsen HM, Thelander G, Ojanperä I, Thordardottir S, Andersen LV, Kriikku P, Vindenes V, Christoffersen D, Delaveris GJ, Frost J (2015)
Fatal poisoning in drug addicts in the Nordic countries in 2012
Forensic Sci Int, 248, 172-80
DOI 10.1016/j.forsciint.2015.01.003, PubMed 25645132

Tuv SS, Bergh MS, Vindenes V, Karinen R (2015)
Methiopropamine in blood samples from drivers suspected of being under the influence of drugs
Traffic Inj Prev, 17 (1), 1-4
DOI 10.1080/15389588.2015.1036157, PubMed 25874580

Publications 2014

Andås HT, Krabseth HM, Enger A, Marcussen BN, Haneborg AM, Christophersen AS, Vindenes V, Øiestad EL (2014)
Detection time for THC in oral fluid after frequent cannabis smoking
Ther Drug Monit, 36 (6), 808-14
DOI 10.1097/FTD.0000000000000092, PubMed 24819969

Berg T, Karlsen M, Oiestad AM, Johansen JE, Liu H, Strand DH (2014)
Evaluation of ¹³C- and ²H-labeled internal standards for the determination of amphetamines in biological samples, by reversed-phase ultra-high performance liquid chromatography-tandem mass spectrometry
J Chromatogr A, 1344, 83-90
DOI 10.1016/j.chroma.2014.04.020, PubMed 24780257

Bogen IL, Boix F, Nerem E, Mørland J, Andersen JM (2014)
A monoclonal antibody specific for 6-monoacetylmorphine reduces acute heroin effects in mice
J Pharmacol Exp Ther, 349 (3), 568-76
DOI 10.1124/jpet.113.212035, PubMed 24700886

Bramness JG, Reid MJ, Solvik KF, Vindenes V (2014)
Recent trends in the availability and use of amphetamine and methamphetamine in Norway
Forensic Sci Int, 246, 92-7
DOI 10.1016/j.forsciint.2014.11.010, PubMed 25485948

Breivik T, Bogen IL, Haug KH, Fonnum F, Opstad PK, Eide DM, Myhre O (2014)
Effects of long-term exposure of 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy") on neuronal transmitter transport, brain immuno-regulatory systems and progression of experimental periodontitis in rats
Neurochem Int, 72, 30-6
DOI 10.1016/j.neuint.2014.04.002, PubMed 24726767

Eriksen GS, Andersen JM, Boix F, Mørland J (2014)
3-Methoxynaltrexone is not a selective antagonist for the acute psychomotor stimulating effects of heroin and 6-monoacetylmorphine in mice
Pharmacol Biochem Behav, 122, 82-8
DOI 10.1016/j.pbb.2014.03.018, PubMed 24699386

Gottås A, Boix F, Øiestad EL, Vindenes V, Mørland J (2014)
Role of 6-monoacetylmorphine in the acute release of striatal dopamine induced by intravenous heroin
Int J Neuropsychopharmacol, 17 (9), 1357-65
DOI 10.1017/S1461145714000169, PubMed 24576415

Høiseth G, Fjeld B, Burns ML, Strand DH, Vindenes V (2014)
Long-term stability of morphine, codeine, and 6-acetylmorphine in real-life whole blood samples, stored at -20°C
Forensic Sci Int, 239, 6-10
DOI 10.1016/j.forsciint.2014.03.008, PubMed 24709028

Karinen R, Fosen JT, Rogde S, Vindenes V (2014)
An accidental poisoning with mitragynine
Forensic Sci Int, 245, e29-32
DOI 10.1016/j.forsciint.2014.10.025, PubMed 25453780

Karinen R, Tuv SS, Rogde S, Peres MD, Johansen U, Frost J, Vindenes V, Øiestad ÅM (2014)
Lethal poisonings with AH-7921 in combination with other substances
Forensic Sci Int, 244, e21-4
DOI 10.1016/j.forsciint.2014.08.013, PubMed 25216892

Karinen R, Tuv SS, Øiestad EL, Vindenes V (2014)
Concentrations of APINACA, 5F-APINACA, UR-144 and its degradant product in blood samples from six impaired drivers compared to previous reported concentrations of other synthetic cannabinoids
Forensic Sci Int, 246, 98-103
DOI 10.1016/j.forsciint.2014.11.012, PubMed 25485949

Karinen R, Vindenes V, Hasvold I, Olsen KM, Christophersen AS, Øiestad E (2014)
Determination of a selection of anti-epileptic drugs and two active metabolites in whole blood by reversed phase UPLC-MS/MS and some examples of application of the method in forensic toxicology cases
Drug Test Anal, 7 (7), 634-44
DOI 10.1002/dta.1733, PubMed 25331692

Thaulow CH, Høiseth G, Andersen JM, Handal M, Mørland J (2014)
Pharmacokinetic interactions between ethanol and heroin: a study on post-mortem cases
Forensic Sci Int, 242, 127-134
DOI 10.1016/j.forsciint.2014.06.032, PubMed 25050840

Viluksela M, Heikkinen P, van der Ven LT, Rendel F, Roos R, Esteban J, Korkalainen M, Lensu S, Miettinen HM, Savolainen K, Sankari S, Lilienthal H, Adamsson A, Toppari J, Herlin M, Finnilä M, Tuukkanen J, Leslie HA, Hamers T, Hamscher G, Al-Anati L, Stenius U, Dervola KS, Bogen IL, Fonnum F et al. (2014)
Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats
PLoS One, 9 (8), e104639
DOI 10.1371/journal.pone.0104639, PubMed 25137063

Vindenes V, Boix F, Koksæter P, Strand MC, Bachs L, Mørland J, Gjerde H (2014)
Drugged driving arrests in Norway before and after the implementation of per se law
Forensic Sci Int, 245, 171-7
DOI 10.1016/j.forsciint.2014.10.038, PubMed 25447190

Vindenes V, Enger A, Nordal K, Johansen U, Christophersen AS, Oiestad EL (2014)
Very long Detection Times after High and repeated intake of Heroin and Methadone, measured in Oral Fluid
Scand. J. Forensic Sci., 20 (2), 34-41
DOI 10.2478/sjfs-2014-0004

Vindenes V, Enger A, Nordal K, Johansen U, Cristophersen AS, Øiestad EL (2014)
Very long Detection Times after High and repeated intake of Heroin and Methadone, measured in Oral Fluid
Scandinavian Journal of Forensic Science, 20 (2), 34-41
DOI 10.2478/sjfs-2014-0004, PublikaID 292

Publications 2013

Amundsen I, Oiestad ÅM, Ekeberg D, Kristoffersen L (2013)
Quantitative determination of fifteen basic pharmaceuticals in ante- and post-mortem whole blood by high pH mobile phase reversed phase ultra high performance liquid chromatography-tandem mass spectrometry
J Chromatogr B Analyt Technol Biomed Life Sci, 927, 112-23
DOI 10.1016/j.jchromb.2012.12.039, PubMed 23380540

Andersen JM, Haugen KS, Ripel A, Mørland J (2013)
The interference of ethanol with heroin-stimulated psychomotor activation in mice is not related to changed brain concentrations of the active metabolites 6MAM or morphine
Basic Clin Pharmacol Toxicol, 114 (2), 197-201
DOI 10.1111/bcpt.12133, PubMed 24102968

Berg-Pedersen RM, Ripel A, Karinen R, Vevelstad M, Bachs L, Vindenes V (2013)
Codeine to morphine concentration ratios in samples from living subjects and autopsy cases after incubation
J Anal Toxicol, 38 (2), 99-105
DOI 10.1093/jat/bkt099, PubMed 24324229

Berntsen HF, Wigestrand MB, Bogen IL, Fonnum F, Walaas SI, Moldes-Anaya A (2013)
Mechanisms of penitrem-induced cerebellar granule neuron death in vitro: possible involvement of GABAA receptors and oxidative processes
Neurotoxicology, 35, 129-36
DOI 10.1016/j.neuro.2013.01.004, PubMed 23313729

Gottås A, Øiestad EL, Boix F, Vindenes V, Ripel Å, Thaulow CH, Mørland J (2013)
Levels of heroin and its metabolites in blood and brain extracellular fluid after i.v. heroin administration to freely moving rats
Br J Pharmacol, 170 (3), 546-56
DOI 10.1111/bph.12305, PubMed 23865556

Høiseth G, Andersen JM, Mørland J (2013)
Less glucuronidation of morphine in the presence of ethanol in vivo
Eur J Clin Pharmacol, 69 (9), 1683-7
DOI 10.1007/s00228-013-1533-5, PubMed 23739999

Karinen R, Vindenes V, Morild I, Johnsen L, Le Nygaard I, Christophersen AS (2013)
Methyl tert-butyl ether (MTBE) detected in abnormally high concentrations in postmortem blood and urine from two persons found dead inside a car containing a gasoline spill
J Forensic Sci, 58 (5), 1393-1396
DOI 10.1111/1556-4029.12208, PubMed 23879346

Tuv SS, Krabseth H, Karinen R, Olsen KM, Øiestad EL, Vindenes V (2013)
Prevalence of synthetic cannabinoids in blood samples from Norwegian drivers suspected of impaired driving during a seven weeks period
Accid Anal Prev, 62, 26-31
DOI 10.1016/j.aap.2013.09.009, PubMed 24129318

Vindenes V, Strand DH, Kristoffersen L, Boix F, Mørland J (2013)
Has the intake of THC by cannabis users changed over the last decade? Evidence of increased exposure by analysis of blood THC concentrations in impaired drivers
Forensic Sci Int, 226 (1-3), 197-201
DOI 10.1016/j.forsciint.2013.01.017, PubMed 23415163

Øiestad EL, Karinen R, Christophersen AS, Vindenes V, Bachs L (2013)
Analyses of beverage remains in drug rape cases revealing drug residues--the possibility of contamination from drug concentrated oral fluid or oral cavity contained tablets
J Forensic Sci, 59 (1), 208-10
DOI 10.1111/1556-4029.12270, PubMed 24117495

Publications 2012

Andersen JM, Klykken C, Mørland J (2012)
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain
J Pharm Pharmacol, 64 (6), 843-7
DOI 10.1111/j.2042-7158.2012.01469.x, PubMed 22571262

Andersen JM, Klykken C, Mørland J (2012)
Long-term methadone treatment reduces phosphorylation of CaMKII in rat brain
J Pharm Pharmacol, Jun;64(6), 843-7
DOI 10.1111/j.2042-7158.2012.01469.x, PublikaID 276

Dervola KS, Roberg BA, Wøien G, Bogen IL, Sandvik TH, Sagvolden T, Drevon CA, Johansen EB, Walaas SI (2012)
Marine Ο-3 polyunsaturated fatty acids induce sex-specific changes in reinforcer-controlled behaviour and neurotransmitter metabolism in a spontaneously hypertensive rat model of ADHD
Behav Brain Funct, 8, 56
DOI 10.1186/1744-9081-8-56, PubMed 23228189

Fjeld B, Burns ML, Karinen R, Larssen B, Smith-Kielland A, Vindenes V (2012)
Long-term stability of GHB in post-mortem samples and samples from living persons, stored at -20°C, using fluoride preservatives
Forensic Sci Int, 222 (1-3), 47-51
DOI 10.1016/j.forsciint.2012.04.033, PubMed 22648054

Gottas A, Oiestad EL, Boix F, Ripel A, Thaulow CH, Pettersen BS, Vindenes V, Morland J (2012)
Simultaneous measurement of heroin and its metabolites in brain extracellular fluid by microdialysis and ultra performance liquid chromatography tandem mass spectrometry
J Pharmacol Toxicol Methods, 66 (1), 14-21
DOI 10.1016/j.vascn.2012.04.009, PubMed 22561414

Sankararaman A, Masiulis I, Richardson DR, Andersen JM, Mørland J, Eisch AJ (2012)
Methadone does not alter key parameters of adult hippocampal neurogenesis in the heroin-naïve rat
Neurosci Lett, 516 (1), 99-104
DOI 10.1016/j.neulet.2012.03.066, PubMed 22487733

Storhaug LW, Enger A, Hjelmeland K, Øiestad EL, Vindenes V (2012)
Prolonged excretion of 7-aminoclonazepam in urine after repeated ingestion of clonazepam: a case report
Forensic Sci Int, 222 (1-3), e33-5
DOI 10.1016/j.forsciint.2012.06.018, PubMed 22819278

Tuv SS, Strand MC, Karinen R, Øiestad EL, Christophersen AS, Vindenes V (2012)
[Effect and occurrence of synthetic cannabinoids]
Tidsskr Nor Laegeforen, 132 (20), 2285-8
DOI 10.4045/tidsskr.12.0471, PubMed 23736196

Vindenes V, Lund HM, Andresen W, Gjerde H, Ikdahl SE, Christophersen AS, Øiestad EL (2012)
Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers
Forensic Sci Int, 219 (1-3), 165-71
DOI 10.1016/j.forsciint.2012.01.001, PubMed 22284072

Vindenes V, Lund HME, Andresen W, Gjerde H, Ikdahl SE, Christophersen AS, Øiestad EL (2012)
Detection of drugs of abuse in simultaneously collected oral fluid, urine and blood from Norwegian drug drivers
Forensic Sci Int, 219 (1-3), 165
PublikaID 265

Vindenes V, Slørdal L, Mørland J (2012)
[Fixed limits for central stimulants in traffic]
Tidsskr Nor Laegeforen, 132 (3), 275-6
DOI 10.4045/tidsskr.11.1284, PubMed 22314734

Wendt A, Speidel D, Danielsson A, Esguerra JL, Bogen IL, Walaas SI, Salehi A, Eliasson L (2012)
Synapsins I and II are not required for insulin secretion from mouse pancreatic β-cells
Endocrinology, 153 (5), 2112-9
DOI 10.1210/en.2011-1702, PubMed 22334712

Publications 2011

Andersen JM, Olaussen CF, Ripel A, Mørland J (2011)
Long-term methadone treatment impairs novelty preference in rats both when present and absent in brain tissue
Pharmacol Biochem Behav, 98 (3), 412-6
DOI 10.1016/j.pbb.2011.02.017, PubMed 21352846

Bogen IL, Jensen V, Hvalby Ø, Walaas SI (2011)
Glutamatergic neurotransmission in the synapsin I and II double knock-out mouse
Semin Cell Dev Biol, 22 (4), 400-7
DOI 10.1016/j.semcdb.2011.07.004, PubMed 21827868

Boix F, Andersen JM, Mørland J (2011)
Pharmacokinetic modeling of subcutaneous heroin and its metabolites in blood and brain of mice
Addict Biol, 18 (1), 1-7
DOI 10.1111/j.1369-1600.2010.00298.x, PubMed 21481103

Oiestad EL, Johansen U, Oiestad AM, Christophersen AS (2011)
Drug screening of whole blood by ultra-performance liquid chromatography-tandem mass spectrometry
J Anal Toxicol, 35 (5), 280-93
DOI 10.1093/anatox/35.5.280, PubMed 21619723

Sauve EN, Langødegård M, Ekeberg D, Øiestad AM (2011)
Determination of benzodiazepines in ante-mortem and post-mortem whole blood by solid-supported liquid-liquid extraction and UPLC-MS/MS
J Chromatogr B Analyt Technol Biomed Life Sci, 883-884, 177-88
DOI 10.1016/j.jchromb.2011.10.033, PubMed 22119506

Vindenes V, Jordbru D, Knapskog AB, Kvan E, Mathisrud G, Slørdal L, Mørland J (2011)
Impairment based legislative limits for driving under the influence of non-alcohol drugs in Norway
Forensic Sci Int, 219 (1-3), 1-11
DOI 10.1016/j.forsciint.2011.11.004, PubMed 22118917

Vindenes V, Yttredal B, Oiestad EL, Waal H, Bernard JP, Mørland JG, Christophersen AS (2011)
Oral fluid is a viable alternative for monitoring drug abuse: detection of drugs in oral fluid by liquid chromatography-tandem mass spectrometry and comparison to the results from urine samples from patients treated with Methadone or Buprenorphine
J Anal Toxicol, 35 (1), 32-9
DOI 10.1093/anatox/35.1.32, PubMed 21219701

Publications 2010

Gjerde H, Øiestad EL, Øiestad ÅM, Langødegård M, Gustavsen I, Hjelmeland K, Bernard JP, Christophersen AS (2010)
Comparison of zopiclone concentrations in oral fluid sampled with Intercept(®) oral specimen collection device and Statsure Saliva Sampler™ and concentrations in blood
J Anal Toxicol, 34 (9), 590-3
DOI 10.1093/jat/34.9.590, PubMed 21073813

Publications 2009

Andersen JM, Ripel A, Boix F, Normann PT, Mørland J (2009)
Increased locomotor activity induced by heroin in mice: pharmacokinetic demonstration of heroin acting as a prodrug for the mediator 6-monoacetylmorphine in vivo
J Pharmacol Exp Ther, 331 (1), 153-61
DOI 10.1124/jpet.109.152462, PubMed 19541908

Bogen IL, Haug KH, Roberg B, Fonnum F, Walaas SI (2009)
The importance of synapsin I and II for neurotransmitter levels and vesicular storage in cholinergic, glutamatergic and GABAergic nerve terminals
Neurochem Int, 55 (1-3), 13-21
DOI 10.1016/j.neuint.2009.02.006, PubMed 19428802

Karinen R, Andersen JM, Ripel A, Hasvold I, Hopen AB, Mørland J, Christophersen AS (2009)
Determination of heroin and its main metabolites in small sample volumes of whole blood and brain tissue by reversed-phase liquid chromatography-tandem mass spectrometry
J Anal Toxicol, 33 (7), 345-50
DOI 10.1093/jat/33.7.345, PubMed 19796503

Vindenes V, Pettersen BS, Gottås A, Christiansen NL, Boix F, Mørland J (2009)
Different effects on dopamine release in nucleus accumbens in mice by the morphine metabolites morphine-6-glucuronide and morphine-3-glucuronide
Basic Clin Pharmacol Toxicol, 105 (5), 357-60
DOI 10.1111/j.1742-7843.2009.00451.x, PubMed 19663818

Vindenes V, Ripel A, Handal M, Boix F, Mørland J (2009)
Interactions between morphine and the morphine-glucuronides measured by conditioned place preference and locomotor activity
Pharmacol Biochem Behav, 93 (1), 1-9
DOI 10.1016/j.pbb.2009.03.013, PubMed 19351545

Publications 2008

Bogen IL, Jensen V, Hvalby O, Walaas SI (2008)
Synapsin-dependent development of glutamatergic synaptic vesicles and presynaptic plasticity in postnatal mouse brain
Neuroscience, 158 (1), 231-41
DOI 10.1016/j.neuroscience.2008.05.055, PubMed 18606212

Bogen IL, Risa Ø, Haug KH, Sonnewald U, Fonnum F, Walaas SI (2008)
Distinct changes in neuronal and astrocytic amino acid neurotransmitter metabolism in mice with reduced numbers of synaptic vesicles
J Neurochem, 105 (6), 2524-34
DOI 10.1111/j.1471-4159.2008.05344.x, PubMed 18346203

Vindenes V, Handal M, Ripel A, Thaulow CH, Vindenes HB, Boix F, Mørland J (2008)
Different time schedules affect conditioned place preference after morphine and morphine-6-glucuronide administration
Pharmacol Biochem Behav, 89 (3), 374-83
DOI 10.1016/j.pbb.2008.01.012, PubMed 18308383

Vindenes V, Karinen R, Hasvold I, Bernard JP, Mørland JG, Christophersen AS (2008)
Bromadiolone poisoning: LC-MS method and pharmacokinetic data
J Forensic Sci, 53 (4), 993-6
DOI 10.1111/j.1556-4029.2008.00737.x, PubMed 18482378

Publications 2007

Wilson SR, Jankowski M, Pepaj M, Mihailova A, Boix F, Truyols GV, Lundanes E, Greibrokk T (2007)
2D LC separation and determination of bradykinin in rat muscle tissue dialysate with on-line SPE-HILIC-SPE-RP-MS
Chromatographia, 66 (7-8), 469-474
DOI 10.1365/s10337-007-0341-4

Publications 2006

Bogen IL, Boulland JL, Mariussen E, Wright MS, Fonnum F, Kao HT, Walaas SI (2006)
Absence of synapsin I and II is accompanied by decreases in vesicular transport of specific neurotransmitters
J Neurochem, 96 (5), 1458-66
DOI 10.1111/j.1471-4159.2005.03636.x, PubMed 16478532

Hallberg OE, Bogen IL, Reistad T, Haug KH, Wright MS, Fonnum F, Walaas SI (2006)
Differential development of vesicular glutamate transporters in brain: an in vitro study of cerebellar granule cells
Neurochem Int, 48 (6-7), 579-85
DOI 10.1016/j.neuint.2005.12.027, PubMed 16517018

Vindenes V, Handal M, Ripel A, Boix F, Mørland J (2006)
Conditioned place preference induced by morphine and morphine-6-glucuronide in mice
Pharmacol Biochem Behav, 85 (2), 292-7
DOI 10.1016/j.pbb.2006.08.010, PubMed 17011617

Zahl PH, Gøtzsche PC, Andersen JM, Maehlen J (2006)
Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Dan Med Bull, 53 (4), 438-40
PubMed 17150148

Zahl PH, Gøtzsche PC, Andersen JM, Mæhlen J (2006)
WITHDRAWN: Results of the Two-County trial of mammography screening are not compatible with contemporaneous official Swedish breast cancer statistics
Eur J Cancer (in press)
DOI 10.1016/j.ejca.2005.12.016, PubMed 16530407

Publications 2005

Gundersen Y, Vaagenes P, Thrane I, Bogen IL, Haug KH, Reistad T, Opstad PK (2005)
Response of circulating immune cells to major gunshot injury, haemorrhage, and acute surgery
Injury, 36 (8), 949-55
DOI 10.1016/j.injury.2004.09.021, PubMed 15982652

Gylterud Owe S, Bogen IL, Walaas SI, Storm-Mathisen J, Bergersen LH (2005)
Ultrastructural quantification of glutamate receptors at excitatory synapses in hippocampus of synapsin I+II double knock-out mice
Neuroscience, 136 (3), 769-77
DOI 10.1016/j.neuroscience.2005.08.056, PubMed 16344150

Haug KH, Bogen IL, Osmundsen H, Walaas I, Fonnum F (2005)
Effects on cholinergic markers in rat brain and blood after short and prolonged administration of donepezil
Neurochem Res, 30 (12), 1511-20
DOI 10.1007/s11064-005-8828-6, PubMed 16362770

Myhrer T, Andersen JM, Nguyen NH, Aas P (2005)
Soman-induced convulsions in rats terminated with pharmacological agents after 45 min: neuropathology and cognitive performance
Neurotoxicology, 26 (1), 39-48
DOI 10.1016/j.neuro.2004.07.011, PubMed 15527872

Nielsen SB, Øiestad ML, Bojesen G, Uggerud E (2005)
Binding of molecular oxygen and alkenes to coordinatively unsaturated bipyridinium metal complexes int the gas phase
International Journal of Mass Spectrometry , 243, p 231-239
PublikaID 452

Wilson SR, Boix F, Holm A, Molander P, Lundanes E, Greibrokk T (2005)
Determination of bradykinin and arg-bradykinin in rat muscle tissue by microdialysis and capillary column-switching liquid chromatography with mass spectrometric detection
J Sep Sci, 28 (14), 1751-8
DOI 10.1002/jssc.200500062, PubMed 16224970

Publications 2004

Boix F, Røe C, Rosenborg L, Knardahl S (2004)
Kinin peptides in human trapezius muscle during sustained isometric contraction and their relation to pain
J Appl Physiol (1985), 98 (2), 534-40
DOI 10.1152/japplphysiol.01340.2003, PubMed 15475593

Myhre O, Sterri SH, Bogen IL, Fonnum F (2004)
Erk1/2 phosphorylation and reactive oxygen species formation via nitric oxide and Akt-1/Raf-1 crosstalk in cultured rat cerebellar granule cells exposed to the organic solvent 1,2,4-trimethylcyclohexane
Toxicol Sci, 80 (2), 296-303
DOI 10.1093/toxsci/kfh166, PubMed 15141098

Myhrer T, Nguyen NH, Andersen JM, Aas P (2004)
Protection against soman-induced seizures in rats: relationship among doses of prophylactics, soman, and adjuncts
Toxicol Appl Pharmacol, 196 (3), 327-36
DOI 10.1016/j.taap.2004.01.007, PubMed 15094303

Zahl PH, Andersen JM, Maehlen J (2004)
Spontaneous regression of cancerous tumors detected by mammography screening
JAMA, 292 (21), 2579-80; author reply 2580
DOI 10.1001/jama.292.21.2579, PubMed 15572712

Publications 2003

Andersen JM, Fonnum F, Myhrer T (2003)
D-Serine alleviates retrograde amnesia of a visual discrimination task in rats with a lesion of the perirhinal cortex
Brain Res, 979 (1-2), 240-4
DOI 10.1016/s0006-8993(03)02894-4, PubMed 12850593

Andersen JM, Myhre O, Fonnum F (2003)
Discussion of the role of the extracellular signal-regulated kinase-phospholipase A2 pathway in production of reactive oxygen species in Alzheimer's disease
Neurochem Res, 28 (2), 319-26
DOI 10.1023/a:1022389503105, PubMed 12608704

Andersen JM, Myhre O, Aarnes H, Vestad TA, Fonnum F (2003)
Identification of the hydroxyl radical and other reactive oxygen species in human neutrophil granulocytes exposed to a fragment of the amyloid beta peptide
Free Radic Res, 37 (3), 269-79
DOI 10.1080/1071576021000046631, PubMed 12688422

Bogen IL, Haug KH, Myhre O, Fonnum F (2003)
Short- and long-term effects of MDMA ("ecstasy") on synaptosomal and vesicular uptake of neurotransmitters in vitro and ex vivo
Neurochem Int, 43 (4-5), 393-400
DOI 10.1016/s0197-0186(03)00027-5, PubMed 12742084

Gundersen Y, Vaagenes P, Myhre O, Andersen JM (2003)
[Pharmacological modulation of the inflammatory response after gunshot injuries in the pig]
Tidsskr Nor Laegeforen, 123 (8), 1054-7
PubMed 12760219

Gundersen Y, Vaagenes P, Myhre O, Andersen JM, Pharo A, Haugen AH, Valoe E, Opstad PK (2003)
Hydrocortisone and the mitogen-activated protein kinase inhibitor U0126 acutely suppress reactive oxygen species generation from circulating granulocytes after gunshot injuries in the pig
Crit Care Med, 31 (1), 166-70
DOI 10.1097/00003246-200301000-00026, PubMed 12545011

Myhre O, Andersen JM, Aarnes H, Fonnum F (2003)
Evaluation of the probes 2',7'-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation
Biochem Pharmacol, 65 (10), 1575-82
DOI 10.1016/s0006-2952(03)00083-2, PubMed 12754093

Publications 2002

Andersen JM, Lindberg V, Myhrer T (2002)
Effects of scopolamine and D-cycloserine on non-spatial reference memory in rats
Behav Brain Res, 129 (1-2), 211-6
DOI 10.1016/s0166-4328(01)00318-7, PubMed 11809513

Boix F (2002)
Vasopeptidase inhibitors: a bradykinin link
Lancet, 359 (9312), 1157-8
DOI 10.1016/S0140-6736(02)08142-4, PubMed 11943297

Boix F, Rosenborg L, Hilgenfeldt U, Knardahl S (2002)
Contraction-related factors affect the concentration of a kallidin-like peptide in rat muscle tissue
J Physiol, 544 (Pt 1), 127-36
DOI 10.1113/jphysiol.2002.025106, PubMed 12356886

Publications 2001

Øiestad ML, Petersen AC, Bakken V, Vedde J, Uggerud E (2001)
The oxidative power of protonated hydrogen peroxide
Angewandte Chemie, 113, p. 1345-1349
PublikaID 450

Publications 2000

Øiestad ML, Uggerud E (2000)
Mediatiors for hydrogenation of carbon monoxide: theoretical study of addition of H2 to HCO+ in the presence of CO or H2O
International Journal of Mass Spectrometry , 201, p. 179-185
PublikaID 448

Øiestad ML, Uggerud E (2000)
Gas phase reactivity of small cationic cobalt clusters towards methanol
Chemical Physics , 262, p. 169-177
PublikaID 449

Publications 1997

Øiestad ML, Uggerud E (1997)
Loss of H2 from CH2NH2+ and NHNH2+. Reaction mechanisms and dynamics from observation of metastable ion fragmentations and ab initio calculations
International Journal of Mass Spectrometry and Ion Processes, 167/168, p 117-126
PublikaID 447

Publications 1995

Øiestad EL, Øiestad ML, Skaane H, Ruud K, Helgaker T, Uggerud E (1995)
Loss of H-2 from CH3NH3+, CH3OH2+ and CH3FH+ - Reaction-Mechanisms and Dynamics from Observation of Metastable Ion Fragmentations and Ab-Initio Calculations Reaction-Mechanisms
Europeamn Mass Spectrometry, 1 (2), 121-129
PublikaID 366