Publications by Jan Magnus Aronsen

90 publications found

Publications 2026

  1. Silva GJJ, Stefani S, Parvan R, Frisk M, Shen X, Alunni Cardinali M, Strand ME, Rypdal KB, Stokke MK, Attramadal H, Lunde IG, Aronsen JM, Stensløkken KO, Louch WE, Sassi P, Cataliotti A (2026)
    Effects of proANP31-67 in a preclinical model of uninephrectomy and cardiac ischemia/reperfusion injury: cardiac remodeling and tissue biochemical profiling
    Am J Physiol Cell Physiol, 330 (5), C1246-C1259
    DOI 10.1152/ajpcell.00339.2025, PubMed 41830464
  2. Veras I, Eken OS, Levy FO, Melleby AO, Aronsen JM (2026)
    Protocol for isolation of nuclei from murine cardiac tissue for single-nucleus multiomic sequencing
    STAR Protoc, 7 (2), 104615
    DOI 10.1016/j.xpro.2026.104615, PubMed 42250224

Publications 2025

  1. Mathiesen SB, Støle TP, Romaine A, Lunde M, Martinsen M, Aronsen JM, Sjaastad I, Louch WE, Christensen G, Carlson CR (2025)
    Syndecan-4 interacts directly with β-parvin and regulates the ILK-PINCH-β-parvin complex, the β-parvin-β-PIX-Rac1 axis, and cardiomyocyte geometry in a sex-dependent manner
    Front Cell Dev Biol, 13, 1569185
    DOI 10.3389/fcell.2025.1569185, PubMed 40977892

Publications 2024

  1. Ruud M, Frisk M, Melleby AO, Norseng PA, Mohamed BA, Li J, Aronsen JM, Setterberg IE, Jakubiczka J, van Hout I, Coffey S, Shen X, Nygård S, Lunde IG, Tønnessen T, Jones PP, Sjaastad I, Gullestad L, Toischer K, Dahl CP, Christensen G, Louch WE (2024)
    Regulation of cardiomyocyte t-tubule structure by preload and afterload: Roles in cardiac compensation and decompensation
    J Physiol, 602 (18), 4487-4510
    DOI 10.1113/JP284566, PubMed 38686538

Publications 2023

  1. Aronsen JM, Skogestad J, Albert I, Melleby AO, Carlson CR (2023)
    Response by Aronsen et al to Letter Regarding Article, "Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure"
    Circulation, 148 (10), 857-858
    DOI 10.1161/CIRCULATIONAHA.123.065884, PubMed 37669357
  2. Sánchez-Pérez P, Mata A, Torp MK, López-Bernardo E, Heiestad CM, Aronsen JM, Molina-Iracheta A, Jiménez-Borreguero LJ, García-Roves P, Costa ASH, Frezza C, Murphy MP, Stenslokken KO, Cadenas S (2023)
    Energy substrate metabolism, mitochondrial structure and oxidative stress after cardiac ischemia-reperfusion in mice lacking UCP3
    Free Radic Biol Med, 205, 244-261
    DOI 10.1016/j.freeradbiomed.2023.05.014, PubMed 37295539
  3. Skogestad J, Albert I, Hougen K, Lothe GB, Lunde M, Eken OS, Veras I, Huynh NTT, Børstad M, Marshall S, Shen X, Louch WE, Robinson EL, Cleveland JC, Ambardekar AV, Schwisow JA, Jonas E, Calejo AI, Morth JP, Taskén K, Melleby AO, Lunde PK, Sjaastad I, Carlson CR, Aronsen JM (2023)
    Disruption of Phosphodiesterase 3A Binding to SERCA2 Increases SERCA2 Activity and Reduces Mortality in Mice With Chronic Heart Failure
    Circulation, 147 (16), 1221-1236
    DOI 10.1161/CIRCULATIONAHA.121.054168, PubMed 36876489
  4. Vistnes M, Erusappan PM, Sasi A, Nordén ES, Bergo KK, Romaine A, Lunde IG, Zhang L, Olsen MB, Øgaard J, Carlson CR, Wang CH, Riise J, Dahl CP, Fiane AE, Hauge-Iversen IM, Espe E, Melleby AO, Tønnessen T, Aronsen JM, Sjaastad I, Christensen G (2023)
    Inhibition of the extracellular enzyme A disintegrin and metalloprotease with thrombospondin motif 4 prevents cardiac fibrosis and dysfunction
    Cardiovasc Res, 119 (10), 1915-1927
    DOI 10.1093/cvr/cvad078, PubMed 37216909

Publications 2022

  1. Lunde IG, Aronsen JM, Melleby AO, Strand ME, Skogestad J, Bendiksen BA, Ahmed MS, Sjaastad I, Attramadal H, Carlson CR, Christensen G (2022)
    Cardiomyocyte-specific overexpression of syndecan-4 in mice results in activation of calcineurin-NFAT signalling and exacerbated cardiac hypertrophy
    Mol Biol Rep, 49 (12), 11795-11809
    DOI 10.1007/s11033-022-07985-y, PubMed 36205855
  2. Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW (2022)
    CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors
    Cardiovasc Res, 118 (6), 1506-1519
    DOI 10.1093/cvr/cvab167, PubMed 33970224
  3. Robinson EL, Drawnel FM, Mehdi S, Archer CR, Liu W, Okkenhaug H, Alkass K, Aronsen JM, Nagaraju CK, Sjaastad I, Sipido KR, Bergmann O, Arthur JSC, Wang X, Roderick HL (2022)
    MSK-Mediated Phosphorylation of Histone H3 Ser28 Couples MAPK Signalling with Early Gene Induction and Cardiac Hypertrophy
    Cells, 11 (4)
    DOI 10.3390/cells11040604, PubMed 35203255
  4. Skogestad J, Aronsen JM (2022)
    Regulation of Cardiac Contractility by the Alpha 2 Subunit of the Na+/K+-ATPase
    Front Physiol, 13, 827334
    DOI 10.3389/fphys.2022.827334, PubMed 35812308
  5. Støle TP, Lunde M, Shen X, Martinsen M, Lunde PK, Li J, Lockwood F, Sjaastad I, Louch WE, Aronsen JM, Christensen G, Carlson CR (2022)
    The female syndecan-4-/- heart has smaller cardiomyocytes, augmented insulin/pSer473-Akt/pSer9-GSK-3β signaling, and lowered SCOP, pThr308-Akt/Akt and GLUT4 levels
    Front Cell Dev Biol, 10, 908126
    DOI 10.3389/fcell.2022.908126, PubMed 36092718

Publications 2021

  1. Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TRS, Dalhus B, Subramanian H, Hille S, Christensen G, Müller OJ, Nikolaev V, Bers DM, Sjaastad I, Shen X, Louch WE, Klussmann E, Sejersted OM (2021)
    AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
    Circ Res, 130 (1), 27-44
    DOI 10.1161/CIRCRESAHA.120.317976, PubMed 34814703
  2. Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
    Exercise Training Stabilizes RyR2-Dependent Ca2+ Release in Post-infarction Heart Failure
    Front Cardiovasc Med, 7, 623922
    DOI 10.3389/fcvm.2020.623922, PubMed 33569394
  3. Frisk M, Le C, Shen X, Røe ÅT, Hou Y, Manfra O, Silva GJJ, van Hout I, Norden ES, Aronsen JM, Laasmaa M, Espe EKS, Zouein FA, Lambert RR, Dahl CP, Sjaastad I, Lunde IG, Coffey S, Cataliotti A, Gullestad L, Tønnessen T, Jones PP, Altara R, Louch WE (2021)
    Etiology-Dependent Impairment of Diastolic Cardiomyocyte Calcium Homeostasis in Heart Failure With Preserved Ejection Fraction
    J Am Coll Cardiol, 77 (4), 405-419
    DOI 10.1016/j.jacc.2020.11.044, PubMed 33509397
  4. Wanichawan P, Skogestad J, Lunde M, Støle TP, Stensland M, Nyman TA, Sjaastad I, Sejersted OM, Aronsen JM, Carlson CR (2021)
    Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies
    Front Pharmacol, 12, 638646
    DOI 10.3389/fphar.2021.638646, PubMed 34163352

Publications 2020

  1. Louwe MC, Olsen MB, Kaasbøll OJ, Yang K, Fosshaug LE, Alfsnes K, Øgaard JDS, Rashidi A, Skulberg VM, Yang M, de Miranda Fonseca D, Sharma A, Aronsen JM, Schrumpf E, Ahmed MS, Dahl CP, Nyman TA, Ueland T, Melum E, Halvorsen BE, Bjørås M, Attramadal H, Sjaastad I, Aukrust P, Yndestad A (2020)
    Absence of NLRP3 Inflammasome in Hematopoietic Cells Reduces Adverse Remodeling After Experimental Myocardial Infarction
    JACC Basic Transl Sci, 5 (12), 1210-1224
    DOI 10.1016/j.jacbts.2020.09.013, PubMed 33426377
  2. Rønning SB, Carlson CR, Aronsen JM, Pisconti A, Høst V, Lunde M, Liland KH, Sjaastad I, Kolset SO, Christensen G, Pedersen ME (2020)
    Syndecan-4-/- Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components
    Front Cell Dev Biol, 8, 730
    DOI 10.3389/fcell.2020.00730, PubMed 32850844
  3. Skogestad J, Aronsen JM, Tovsrud N, Wanichawan P, Hougen K, Stokke MK, Carlson CR, Sjaastad I, Sejersted OM, Swift F (2020)
    Coupling of the Na+/K+-ATPase to Ankyrin B controls Na+/Ca2+ exchanger activity in cardiomyocytes
    Cardiovasc Res, 116 (1), 78-90
    DOI 10.1093/cvr/cvz087, PubMed 30949686
  4. Tazmini K, Frisk M, Lewalle A, Laasmaa M, Morotti S, Lipsett DB, Manfra O, Skogestad J, Aronsen JM, Sejersted OM, Sjaastad I, Edwards AG, Grandi E, Niederer SA, Øie E, Louch WE (2020)
    Hypokalemia Promotes Arrhythmia by Distinct Mechanisms in Atrial and Ventricular Myocytes
    Circ Res, 126 (7), 889-906
    DOI 10.1161/CIRCRESAHA.119.315641, PubMed 32070187

Publications 2019

  1. Espe EKS, Aronsen JM, Nordén ES, Zhang L, Sjaastad I (2019)
    Regional right ventricular function in rats: a novel magnetic resonance imaging method for measurement of right ventricular strain
    Am J Physiol Heart Circ Physiol, 318 (1), H143-H153
    DOI 10.1152/ajpheart.00357.2019, PubMed 31774693
  2. Lipsett DB, Frisk M, Aronsen JM, Nordén ES, Buonarati OR, Cataliotti A, Hell JW, Sjaastad I, Christensen G, Louch WE (2019)
    Cardiomyocyte substructure reverts to an immature phenotype during heart failure
    J Physiol, 597 (7), 1833-1853
    DOI 10.1113/JP277273, PubMed 30707448
  3. Mathiesen SB, Lunde M, Aronsen JM, Romaine A, Kaupang A, Martinsen M, de Souza GA, Nyman TA, Sjaastad I, Christensen G, Carlson CR (2019)
    The cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP)
    J Biol Chem, 294 (22), 8717-8731
    DOI 10.1074/jbc.RA118.006423, PubMed 30967474
  4. McGinley G, Bendiksen BA, Zhang L, Aronsen JM, Nordén ES, Sjaastad I, Espe EKS (2019)
    Accelerated magnetic resonance imaging tissue phase mapping of the rat myocardium using compressed sensing with iterative soft-thresholding
    PLoS One, 14 (7), e0218874
    DOI 10.1371/journal.pone.0218874, PubMed 31276508
  5. Mohammadzadeh N, Lunde IG, Andenæs K, Strand ME, Aronsen JM, Skrbic B, Marstein HS, Bandlien C, Nygård S, Gorham J, Sjaastad I, Chakravarti S, Christensen G, Engebretsen KVT, Tønnessen T (2019)
    The extracellular matrix proteoglycan lumican improves survival and counteracts cardiac dilatation and failure in mice subjected to pressure overload
    Sci Rep, 9 (1), 9206
    DOI 10.1038/s41598-019-45651-9, PubMed 31235849
  6. Røe ÅT, Ruud M, Espe EK, Manfra O, Longobardi S, Aronsen JM, Nordén ES, Husebye T, Kolstad TRS, Cataliotti A, Christensen G, Sejersted OM, Niederer SA, Andersen GØ, Sjaastad I, Louch WE (2019)
    Regional diastolic dysfunction in post-infarction heart failure: role of local mechanical load and SERCA expression
    Cardiovasc Res, 115 (4), 752-764
    DOI 10.1093/cvr/cvy257, PubMed 30351410
  7. Skogestad J, Lines GT, Louch WE, Sejersted OM, Sjaastad I, Aronsen JM (2019)
    Evidence for heterogeneous subsarcolemmal Na+ levels in rat ventricular myocytes
    Am J Physiol Heart Circ Physiol, 316 (5), H941-H957
    DOI 10.1152/ajpheart.00637.2018, PubMed 30657726
  8. Sokolova M, Sjaastad I, Louwe MC, Alfsnes K, Aronsen JM, Zhang L, Haugstad SB, Bendiksen BA, Øgaard J, Bliksøen M, Lien E, Berge RK, Aukrust P, Ranheim T, Yndestad A (2019)
    NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity
    Front Immunol, 10, 1621
    DOI 10.3389/fimmu.2019.01621, PubMed 31379826

Publications 2018

  1. Andenæs K, Lunde IG, Mohammadzadeh N, Dahl CP, Aronsen JM, Strand ME, Palmero S, Sjaastad I, Christensen G, Engebretsen KVT, Tønnessen T (2018)
    The extracellular matrix proteoglycan fibromodulin is upregulated in clinical and experimental heart failure and affects cardiac remodeling
    PLoS One, 13 (7), e0201422
    DOI 10.1371/journal.pone.0201422, PubMed 30052659
  2. Kolstad TR, van den Brink J, MacQuaide N, Lunde PK, Frisk M, Aronsen JM, Norden ES, Cataliotti A, Sjaastad I, Sejersted OM, Edwards AG, Lines GT, Louch WE (2018)
    Ryanodine receptor dispersion disrupts Ca2+ release in failing cardiac myocytes
    Elife, 7
    DOI 10.7554/eLife.39427, PubMed 30375974
  3. Melleby AO, Romaine A, Aronsen JM, Veras I, Zhang L, Sjaastad I, Lunde IG, Christensen G (2018)
    A novel method for high precision aortic constriction that allows for generation of specific cardiac phenotypes in mice
    Cardiovasc Res, 114 (12), 1680-1690
    DOI 10.1093/cvr/cvy141, PubMed 29878127
  4. Skogestad J, Aronsen JM (2018)
    Hypokalemia-Induced Arrhythmias and Heart Failure: New Insights and Implications for Therapy
    Front Physiol, 9, 1500
    DOI 10.3389/fphys.2018.01500, PubMed 30464746
  5. Smyrnias I, Goodwin N, Wachten D, Skogestad J, Aronsen JM, Robinson EL, Demydenko K, Segonds-Pichon A, Oxley D, Sadayappan S, Sipido K, Bootman MD, Roderick HL (2018)
    Contractile responses to endothelin-1 are regulated by PKC phosphorylation of cardiac myosin binding protein-C in rat ventricular myocytes
    J Mol Cell Cardiol, 117, 1-18
    DOI 10.1016/j.yjmcc.2018.02.012, PubMed 29470978

Publications 2017

  1. Aronsen JM, Espe EKS, Skårdal K, Hasic A, Zhang L, Sjaastad I (2017)
    Noninvasive stratification of postinfarction rats based on the degree of cardiac dysfunction using magnetic resonance imaging and echocardiography
    Am J Physiol Heart Circ Physiol, 312 (5), H932-H942
    DOI 10.1152/ajpheart.00668.2016, PubMed 28188213
  2. Dhondup Y, Sjaastad I, Sandanger Ø, Aronsen JM, Ahmed MS, Attramadal H, Finsen AV, Zhang L, Ranheim T, Alfsnes K, Aukrust P, Christensen G, Yndestad A, Vinge LE (2017)
    Toll-Like Receptor 9 Promotes Survival in SERCA2a KO Heart Failure Mice
    Mediators Inflamm, 2017, 9450439
    DOI 10.1155/2017/9450439, PubMed 28490840
  3. Espe EKS, Aronsen JM, Eriksen M, Sejersted OM, Zhang L, Sjaastad I (2017)
    Regional Dysfunction After Myocardial Infarction in Rats
    Circ Cardiovasc Imaging, 10 (9)
    DOI 10.1161/CIRCIMAGING.116.005997, PubMed 28838960
  4. Gattoni S, Røe ÅT, Aronsen JM, Sjaastad I, Louch WE, Smith NP, Niederer SA (2017)
    Compensatory and decompensatory alterations in cardiomyocyte Ca2+ dynamics in hearts with diastolic dysfunction following aortic banding
    J Physiol, 595 (12), 3867-3889
    DOI 10.1113/JP273879, PubMed 28542952
  5. Landfors M, Johansen J, Aronsen JM, Vågbø CB, Doré LC, He C, Sjaastad I, Sætrom P, Fedorcsák P, Dahl JA, Aanes H, Fußer M, Klungland A (2017)
    Genome-wide profiling of DNA 5-hydroxymethylcytosine during rat Sertoli cell maturation
    Cell Discov, 3, 17013
    DOI 10.1038/celldisc.2017.13, PubMed 28529766
  6. Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
    PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
    Eur J Pharmacol, 812, 174-183
    DOI 10.1016/j.ejphar.2017.07.014, PubMed 28697992
  7. Romaine A, Sørensen IW, Zeltz C, Lu N, Erusappan PM, Melleby AO, Zhang L, Bendiksen B, Robinson EL, Aronsen JM, Herum KM, Danielsen HE, Sjaastad I, Christensen G, Gullberg D (2017)
    Overexpression of integrin α11 induces cardiac fibrosis in mice
    Acta Physiol (Oxf), 222 (2)
    DOI 10.1111/apha.12932, PubMed 28771943
  8. Røe ÅT, Aronsen JM, Skårdal K, Hamdani N, Linke WA, Danielsen HE, Sejersted OM, Sjaastad I, Louch WE (2017)
    Increased passive stiffness promotes diastolic dysfunction despite improved Ca2+ handling during left ventricular concentric hypertrophy
    Cardiovasc Res, 113 (10), 1161-1172
    DOI 10.1093/cvr/cvx087, PubMed 28472418

Publications 2016

  1. Aronsen JM, Louch WE, Sjaastad I (2016)
    Cardiomyocyte Ca2+ dynamics: clinical perspectives
    Scand Cardiovasc J, 50 (2), 65-77
    DOI 10.3109/14017431.2015.1136079, PubMed 26729487
  2. Espe EKS, Skårdal K, Aronsen JM, Zhang L, Sjaastad I (2016)
    A semiautomatic method for rapid segmentation of velocity-encoded myocardial magnetic resonance imaging data
    Magn Reson Med, 78 (3), 1199-1207
    DOI 10.1002/mrm.26486, PubMed 27699840
  3. Frisk M, Ruud M, Espe EK, Aronsen JM, Røe ÅT, Zhang L, Norseng PA, Sejersted OM, Christensen GA, Sjaastad I, Louch WE (2016)
    Elevated ventricular wall stress disrupts cardiomyocyte t-tubule structure and calcium homeostasis
    Cardiovasc Res, 112 (1), 443-51
    DOI 10.1093/cvr/cvw111, PubMed 27226008
  4. Hortemo KH, Lunde PK, Anonsen JH, Kvaløy H, Munkvik M, Rehn TA, Sjaastad I, Lunde IG, Aronsen JM, Sejersted OM (2016)
    Exercise training increases protein O-GlcNAcylation in rat skeletal muscle
    Physiol Rep, 4 (18)
    DOI 10.14814/phy2.12896, PubMed 27664189
  5. Sadredini M, Danielsen TK, Aronsen JM, Manotheepan R, Hougen K, Sjaastad I, Stokke MK (2016)
    Beta-Adrenoceptor Stimulation Reveals Ca2+ Waves and Sarcoplasmic Reticulum Ca2+ Depletion in Left Ventricular Cardiomyocytes from Post-Infarction Rats with and without Heart Failure
    PLoS One, 11 (4), e0153887
    DOI 10.1371/journal.pone.0153887, PubMed 27096943
  6. Skårdal K, Espe EK, Zhang L, Aronsen JM, Sjaastad I (2016)
    Three-Directional Evaluation of Mitral Flow in the Rat Heart by Phase-Contrast Cardiovascular Magnetic Resonance
    PLoS One, 11 (3), e0150536
    DOI 10.1371/journal.pone.0150536, PubMed 26930073
  7. Thienpont B, Aronsen JM, Robinson EL, Okkenhaug H, Loche E, Ferrini A, Brien P, Alkass K, Tomasso A, Agrawal A, Bergmann O, Sjaastad I, Reik W, Roderick HL (2016)
    The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy
    J Clin Invest, 127 (1), 335-348
    DOI 10.1172/JCI88353, PubMed 27893464

Publications 2015

  1. Dhondup Y, Sjaastad I, Scott H, Sandanger Ø, Zhang L, Haugstad SB, Aronsen JM, Ranheim T, Holmen SD, Alfsnes K, Ahmed MS, Attramadal H, Gullestad L, Aukrust P, Christensen G, Yndestad A, Vinge LE (2015)
    Sustained Toll-Like Receptor 9 Activation Promotes Systemic and Cardiac Inflammation, and Aggravates Diastolic Heart Failure in SERCA2a KO Mice
    PLoS One, 10 (10), e0139715
    DOI 10.1371/journal.pone.0139715, PubMed 26461521
  2. Espe EK, Aronsen JM, Eriksen GS, Zhang L, Smiseth OA, Edvardsen T, Sjaastad I, Eriksen M (2015)
    Assessment of regional myocardial work in rats
    Circ Cardiovasc Imaging, 8 (2), e002695
    DOI 10.1161/CIRCIMAGING.114.002695, PubMed 25673647
  3. Hafver TL, Hodne K, Wanichawan P, Aronsen JM, Dalhus B, Lunde PK, Lunde M, Martinsen M, Enger UH, Fuller W, Sjaastad I, Louch WE, Sejersted OM, Carlson CR (2015)
    Protein Phosphatase 1c Associated with the Cardiac Sodium Calcium Exchanger 1 Regulates Its Activity by Dephosphorylating Serine 68-phosphorylated Phospholemman
    J Biol Chem, 291 (9), 4561-79
    DOI 10.1074/jbc.M115.677898, PubMed 26668322
  4. Hortemo KH, Aronsen JM, Lunde IG, Sjaastad I, Lunde PK, Sejersted OM (2015)
    Exhausting treadmill running causes dephosphorylation of sMLC2 and reduced level of myofilament MLCK2 in slow twitch rat soleus muscle
    Physiol Rep, 3 (2)
    DOI 10.14814/phy2.12285, PubMed 25713325
  5. Lauritzen KH, Kleppa L, Aronsen JM, Eide L, Carlsen H, Haugen ØP, Sjaastad I, Klungland A, Rasmussen LJ, Attramadal H, Storm-Mathisen J, Bergersen LH (2015)
    Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
    Am J Physiol Heart Circ Physiol, 309 (3), H434-49
    DOI 10.1152/ajpheart.00253.2014, PubMed 26055793
  6. Ottesen AH, Louch WE, Carlson CR, Landsverk OJB, Kurola J, Johansen RF, Moe MK, Aronsen JM, Høiseth AD, Jarstadmarken H, Nygård S, Bjørås M, Sjaastad I, Pettilä V, Stridsberg M, Omland T, Christensen G, Røsjø H (2015)
    Secretoneurin is a novel prognostic cardiovascular biomarker associated with cardiomyocyte calcium handling
    J Am Coll Cardiol, 65 (4), 339-351
    DOI 10.1016/j.jacc.2014.10.065, PubMed 25634832
  7. Strand ME, Aronsen JM, Braathen B, Sjaastad I, Kvaløy H, Tønnessen T, Christensen G, Lunde IG (2015)
    Shedding of syndecan-4 promotes immune cell recruitment and mitigates cardiac dysfunction after lipopolysaccharide challenge in mice
    J Mol Cell Cardiol, 88, 133-44
    DOI 10.1016/j.yjmcc.2015.10.003, PubMed 26449522
  8. Zoccarato A, Surdo NC, Aronsen JM, Fields LA, Mancuso L, Dodoni G, Stangherlin A, Livie C, Jiang H, Sin YY, Gesellchen F, Terrin A, Baillie GS, Nicklin SA, Graham D, Szabo-Fresnais N, Krall J, Vandeput F, Movsesian M, Furlan L, Corsetti V, Hamilton G, Lefkimmiatis K, Sjaastad I, Zaccolo M (2015)
    Cardiac Hypertrophy Is Inhibited by a Local Pool of cAMP Regulated by Phosphodiesterase 2
    Circ Res, 117 (8), 707-19
    DOI 10.1161/CIRCRESAHA.114.305892, PubMed 26243800

Publications 2014

  1. Aronsen JM, Skogestad J, Lewalle A, Louch WE, Hougen K, Stokke MK, Swift F, Niederer S, Smith NP, Sejersted OM, Sjaastad I (2014)
    Hypokalaemia induces Ca²⁺ overload and Ca²⁺ waves in ventricular myocytes by reducing Na⁺,K⁺-ATPase α₂ activity
    J Physiol, 593 (6), 1509-21
    DOI 10.1113/jphysiol.2014.279893, PubMed 25772299
  2. Boardman NT, Aronsen JM, Louch WE, Sjaastad I, Willoch F, Christensen G, Sejersted O, Aasum E (2014)
    Impaired left ventricular mechanical and energetic function in mice after cardiomyocyte-specific excision of Serca2
    Am J Physiol Heart Circ Physiol, 306 (7), H1018-24
    DOI 10.1152/ajpheart.00741.2013, PubMed 24486508
  3. Land S, Niederer SA, Louch WE, Røe ÅT, Aronsen JM, Stuckey DJ, Sikkel MB, Tranter MH, Lyon AR, Harding SE, Smith NP (2014)
    Computational modeling of Takotsubo cardiomyopathy: effect of spatially varying β-adrenergic stimulation in the rat left ventricle
    Am J Physiol Heart Circ Physiol, 307 (10), H1487-96
    DOI 10.1152/ajpheart.00443.2014, PubMed 25239804
  4. Melsom CB, Hussain RI, Ørstavik Ø, Aronsen JM, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Krobert KA (2014)
    Non-classical regulation of β1- and β 2-adrenoceptor-mediated inotropic responses in rat heart ventricle by the G protein Gi
    Naunyn Schmiedebergs Arch Pharmacol, 387 (12), 1177-86
    DOI 10.1007/s00210-014-1036-7, PubMed 25216690
  5. Moltzau LR, Aronsen JM, Meier S, Skogestad J, Ørstavik Ø, Lothe GB, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
    Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle
    J Pharmacol Exp Ther, 350 (3), 681-90
    DOI 10.1124/jpet.114.214882, PubMed 25022512
  6. Moltzau LR, Meier S, Aronsen JM, Afzal F, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
    Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium
    Naunyn Schmiedebergs Arch Pharmacol, 387 (5), 407-17
    DOI 10.1007/s00210-013-0953-1, PubMed 24424715
  7. Nordbø O, Lamata P, Land S, Niederer S, Aronsen JM, Louch WE, Sjaastad I, Martens H, Gjuvsland AB, Tøndel K, Torp H, Lohezic M, Schneider JE, Remme EW, Smith N, Omholt SW, Vik JO (2014)
    A computational pipeline for quantification of mouse myocardial stiffness parameters
    Comput Biol Med, 53, 65-75
    DOI 10.1016/j.compbiomed.2014.07.013, PubMed 25129018
  8. Vistnes M, Aronsen JM, Lunde IG, Sjaastad I, Carlson CR, Christensen G (2014)
    Pentosan polysulfate decreases myocardial expression of the extracellular matrix enzyme ADAMTS4 and improves cardiac function in vivo in rats subjected to pressure overload by aortic banding
    PLoS One, 9 (3), e89621
    DOI 10.1371/journal.pone.0089621, PubMed 24595230
  9. Wanichawan P, Hafver TL, Hodne K, Aronsen JM, Lunde IG, Dalhus B, Lunde M, Kvaløy H, Louch WE, Tønnessen T, Sjaastad I, Sejersted OM, Carlson CR (2014)
    Molecular basis of calpain cleavage and inactivation of the sodium-calcium exchanger 1 in heart failure
    J Biol Chem, 289 (49), 33984-98
    DOI 10.1074/jbc.M114.602581, PubMed 25336645

Publications 2013

  1. Aronsen JM, Swift F, Sejersted OM (2013)
    Cardiac sodium transport and excitation-contraction coupling
    J Mol Cell Cardiol, 61, 11-9
    DOI 10.1016/j.yjmcc.2013.06.003, PubMed 23774049
  2. Espe EK, Aronsen JM, Skårdal K, Schneider JE, Zhang L, Sjaastad I (2013)
    Novel insight into the detailed myocardial motion and deformation of the rodent heart using high-resolution phase contrast cardiovascular magnetic resonance
    J Cardiovasc Magn Reson, 15 (1), 82
    DOI 10.1186/1532-429X-15-82, PubMed 24034168
  3. Land S, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sjaastad I, Sejersted OM, Smith NP (2013)
    Beta-adrenergic stimulation maintains cardiac function in Serca2 knockout mice
    Biophys J, 104 (6), 1349-56
    DOI 10.1016/j.bpj.2013.01.042, PubMed 23528094
  4. Moltzau LR, Aronsen JM, Meier S, Nguyen CH, Hougen K, Ørstavik Ø, Sjaastad I, Christensen G, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2013)
    SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
    Br J Pharmacol, 170 (2), 366-79
    DOI 10.1111/bph.12282, PubMed 23808942
  5. Solberg A, Robertson AB, Aronsen JM, Rognmo Ø, Sjaastad I, Wisløff U, Klungland A (2013)
    Deletion of mouse Alkbh7 leads to obesity
    J Mol Cell Biol, 5 (3), 194-203
    DOI 10.1093/jmcb/mjt012, PubMed 23572141

Publications 2012

  1. Drawnel FM, Wachten D, Molkentin JD, Maillet M, Aronsen JM, Swift F, Sjaastad I, Liu N, Catalucci D, Mikoshiba K, Hisatsune C, Okkenhaug H, Andrews SR, Bootman MD, Roderick HL (2012)
    Mutual antagonism between IP(3)RII and miRNA-133a regulates calcium signals and cardiac hypertrophy
    J Cell Biol, 199 (5), 783-98
    DOI 10.1083/jcb.201111095, PubMed 23166348
  2. Espe EK, Aronsen JM, Skrbic B, Skulberg VM, Schneider JE, Sejersted OM, Zhang L, Sjaastad I (2012)
    Improved MR phase-contrast velocimetry using a novel nine-point balanced motion-encoding scheme with increased robustness to eddy current effects
    Magn Reson Med, 69 (1), 48-61
    DOI 10.1002/mrm.24226, PubMed 22392844
  3. Hussain RI, Aronsen JM, Afzal F, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2012)
    The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle
    J Mol Cell Cardiol, 56, 129-38
    DOI 10.1016/j.yjmcc.2012.11.015, PubMed 23220156
  4. Land S, Niederer SA, Aronsen JM, Espe EK, Zhang L, Louch WE, Sjaastad I, Sejersted OM, Smith NP (2012)
    An analysis of deformation-dependent electromechanical coupling in the mouse heart
    J Physiol, 590 (18), 4553-69
    DOI 10.1113/jphysiol.2012.231928, PubMed 22615436
  5. Li L, Louch WE, Niederer SA, Aronsen JM, Christensen G, Sejersted OM, Smith NP (2012)
    Sodium accumulation in SERCA knockout-induced heart failure
    Biophys J, 102 (9), 2039-48
    DOI 10.1016/j.bpj.2012.03.045, PubMed 22824267

Publications 2011

  1. Afzal F, Aronsen JM, Moltzau LR, Sjaastad I, Levy FO, Skomedal T, Osnes JB, Qvigstad E (2011)
    Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle
    Br J Pharmacol, 162 (1), 54-71
    DOI 10.1111/j.1476-5381.2010.00890.x, PubMed 21133887
  2. Afzal F, Qvigstad E, Aronsen JM, Moltzau LR, Sjaastad I, Skomedal T, Osnes JB, Levy FO (2011)
    Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle
    Naunyn Schmiedebergs Arch Pharmacol, 384 (6), 543-53
    DOI 10.1007/s00210-011-0670-6, PubMed 21901315
  3. Hussain RI, Afzal F, Mørk HK, Aronsen JM, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2011)
    Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle
    Br J Pharmacol, 162 (4), 908-16
    DOI 10.1111/j.1476-5381.2010.01097.x, PubMed 21039419
  4. Lunde IG, Aronsen JM, Kvaløy H, Qvigstad E, Sjaastad I, Tønnessen T, Christensen G, Grønning-Wang LM, Carlson CR (2011)
    Cardiac O-GlcNAc signaling is increased in hypertrophy and heart failure
    Physiol Genomics, 44 (2), 162-72
    DOI 10.1152/physiolgenomics.00016.2011, PubMed 22128088
  5. Munkvik M, Lunde PK, Aronsen JM, Birkeland JA, Sjaastad I, Sejersted OM (2011)
    Attenuated fatigue in slow twitch skeletal muscle during isotonic exercise in rats with chronic heart failure
    PLoS One, 6 (7), e22695
    DOI 10.1371/journal.pone.0022695, PubMed 21799933

Publications 2010

  1. Hougen K, Aronsen JM, Stokke MK, Enger U, Nygard S, Andersson KB, Christensen G, Sejersted OM, Sjaastad I (2010)
    Cre-loxP DNA recombination is possible with only minimal unspecific transcriptional changes and without cardiomyopathy in Tg(alphaMHC-MerCreMer) mice
    Am J Physiol Heart Circ Physiol, 299 (5), H1671-8
    DOI 10.1152/ajpheart.01155.2009, PubMed 20802136

Publications 2009

  1. Louch WE, Hougen K, Mørk HK, Swift F, Aronsen JM, Sjaastad I, Reims HM, Roald B, Andersson KB, Christensen G, Sejersted OM (2009)
    Sodium accumulation promotes diastolic dysfunction in end-stage heart failure following Serca2 knockout
    J Physiol, 588 (Pt 3), 465-78
    DOI 10.1113/jphysiol.2009.183517, PubMed 20008467
  2. Qvigstad E, Moltzau LR, Aronsen JM, Nguyen CH, Hougen K, Sjaastad I, Levy FO, Skomedal T, Osnes JB (2009)
    Natriuretic peptides increase beta1-adrenoceptor signalling in failing hearts through phosphodiesterase 3 inhibition
    Cardiovasc Res, 85 (4), 763-72
    DOI 10.1093/cvr/cvp364, PubMed 19900965
  3. Rehn TA, Borge BA, Lunde PK, Munkvik M, Sneve ML, Grøndahl F, Aronsen JM, Sjaastad I, Prydz K, Kolset SO, Wiig H, Sejersted OM, Iversen PO (2009)
    Temporary fatigue and altered extracellular matrix in skeletal muscle during progression of heart failure in rats
    Am J Physiol Regul Integr Comp Physiol, 297 (1), R26-33
    DOI 10.1152/ajpregu.90617.2008, PubMed 19339678
  4. Sharikabad MN, Aronsen JM, Haugen E, Pedersen J, Møller AS, Mørk HK, Aass HC, Sejersted OM, Sjaastad I, Brørs O (2009)
    Cardiomyocytes from postinfarction failing rat hearts have improved ischemia tolerance
    Am J Physiol Heart Circ Physiol, 296 (3), H787-95
    DOI 10.1152/ajpheart.00796.2008, PubMed 19136604

Publications 2008

  1. Afzal F, Andressen KW, Mørk HK, Aronsen JM, Sjaastad I, Dahl CP, Skomedal T, Levy FO, Osnes JB, Qvigstad E (2008)
    5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles
    Br J Pharmacol, 155 (7), 1005-14
    DOI 10.1038/bjp.2008.339, PubMed 18846035
  2. Bøkenes J, Aronsen JM, Birkeland JA, Henriksen UL, Louch WE, Sjaastad I, Sejersted OM (2008)
    Slow contractions characterize failing rat hearts
    Basic Res Cardiol, 103 (4), 328-44
    DOI 10.1007/s00395-008-0719-y, PubMed 18347833
  3. Swift F, Birkeland JA, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM (2008)
    Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure
    Cardiovasc Res, 78 (1), 71-8
    DOI 10.1093/cvr/cvn013, PubMed 18203708
  4. Swift F, Birkeland JAK, Tovsrud N, Enger UH, Aronsen JM, Louch WE, Sjaastad I, Sejersted OM (2008)
    Altered Na(+)/Ca(2+)-exchanger activity due to downregulation of Na(+)/K(+)-ATPase alpha(2)-isoform in heart failure (vol 78, pg 71, 2008)
    Cardiovasc. Res., 79 (2), 352
    DOI 10.1093/cvr/cvn147

 
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