Research Interests:

Adoptive T-cell therapy, genome engineering, CRISPR, Mass-spectrometry

Education:

2019-2023        Ph.D. in Systems Immunology 

Microbiology & Immunology (MIM) Program, ETH Zurich

2012-2013         M.Sc. in Bioresource Engineering

Bioresource Engineering, McGill University

2008-2012         B.Sc. in International Agriculture & Food Systems

Agriculture and Environmental Sciences, McGill University

Work Experience:

2025-Current    Postdoctoral Researcher – Dr. Sébastien Wälchli Lab

                          Oslo University Hospital (OUH)

2024-2025         Postdoctoral Researcher – Dr. Roger Geiger Lab

                          Institute for Research in Biomedicine (IRB)

2018-2019         Research Associate II – Dr. Alexander Marson Lab

                          Department of Microbiology & Immunology

University of California, San Francisco (UCSF)

2017-2018         Research Associate II – Dr. Judy Sakanari Lab

Department of Pharmaceutical Chemistry

University of California, San Francisco (UCSF)

Publications 2025

Vogel, I., Casagranda, A., Cattaneo, M., Morosi, L., Basso, C., Pecoraro, M., Sulheim, E., and Geiger, R. (2025). RNF19B confers tumor resistance to CAR T cells. Preprint at Research Square, https://doi.org/10.21203/rs.3.rs-7847831/v1 https://doi.org/10.21203/rs.3.rs-7847831/v1.

Vogel, I., and Bapat, S.P. (2025). TAMing immunity through an unexpected source. Cancer Cell 43, 1002–1004. https://doi.org/10.1016/j.ccell.2025.04.004.

Publications 2024

Hegde, S., Marriott, A.E., Pionnier, N., Steven, A., Bulman, C., Gunderson, E., Vogel, I., Koschel, M., Ehrens, A., Lustigman, S., et al. (2024). Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis. Front. Microbiol. 15. https://doi.org/10.3389/fmicb.2024.1346068.

Publications 2023

Canale, F. P., Neumann, J., von Renesse, J., Loggi, E., Pecoraro, M., Vogel, I., . . . Geiger, R. (2023). Proteomics of immune cells from liver tumors reveals immunotherapy targets. Cell Genomics, 3(6), 100331. doi:https://doi.org/10.1016/j.xgen.2023.100331

Publications 2022

Bapat, S. P., Whitty, C., Mowery, C. T., Liang, Y., Yoo, A., Jiang, Z., Peters, M. C., Zhang, L. J., Vogel, I., Zhou, C., Nguyen, V. Q., Li, Z., Chang, C., Zhu, W. S., Hastie, A. T., He, H., Ren, X., Qiu, W., Gayer, S. G., Liu, C., … Marson, A. (2022). Obesity alters pathology and treatment response in inflammatory disease. Nature, 604(7905), 337–342. https://doi.org/10.1038/s41586-022-04536-0

Gunderson, E. L., Bryant, C., Bulman, C. A., Fischer, C., Luo, M., Vogel, I., Lim, K. C., Jawahar, S., Tricoche, N., Voronin, D., Corbo, C., Ayiseh, R. B., Manfo, F., Mbah, G. E., Cho-Ngwa, F., Beerntsen, B., Renslo, A. R., Lustigman, S., & Sakanari, J. A. (2022). Pyrvinium Pamoate and Structural Analogs Are Early Macrofilaricide Leads. Pharmaceuticals (Basel, Switzerland), 15(2), 189. https://doi.org/10.3390/ph15020189

Publications 2021

Bulman, C. A., Chappell, L., Gunderson, E., Vogel, I., Beerntsen, B., Slatko, B. E., Sullivan, W., & Sakanari, J. A. (2021). The Eagle effect in the Wolbachia-worm symbiosis. Parasites & vectors, 14(1), 118. https://doi.org/10.1186/s13071-020-04545-w

Publications 2020

Wolf, T., Jin, W., Zoppi, G., Vogel, I. A., Akhmedov, M., Bleck, C., Beltraminelli, T., Rieckmann, J. C., Ramirez, N. J., Benevento, M., Notarbartolo, S., Bumann, D., Meissner, F., Grimbacher, B., Mann, M., Lanzavecchia, A., Sallusto, F., Kwee, I., & Geiger, R. (2020). Dynamics in protein translation sustaining T cell preparedness. Nature immunology, 21(8), 927–937. https://doi.org/10.1038/s41590-020-0714-5

Gunderson, E. L., Vogel, I., Chappell, L., Bulman, C. A., Lim, K. C., Luo, M., Whitman, J. D., Franklin, C., Choi, Y. J., Lefoulon, E., Clark, T., Beerntsen, B., Slatko, B., Mitreva, M., Sullivan, W., & Sakanari, J. A. (2020). The endosymbiont Wolbachia rebounds following antibiotic treatment. PLoS pathogens, 16(7), e1008623. https://doi.org/10.1371/journal.ppat.1008623

Cortez, J. T., Montauti, E., Shifrut, E., Gatchalian, J., Zhang, Y., Shaked, O., Xu, Y., Roth, T. L., Simeonov, D. R., Zhang, Y., Chen, S., Li, Z., Woo, J. M., Ho, J., Vogel, I. A., Prator, G. Y., Zhang, B., Lee, Y., Sun, Z., Ifergan, I., … Fang, D. (2020). CRISPR screen in regulatory T cells reveals modulators of Foxp3. Nature, 582(7812), 416–420. https://doi.org/10.1038/s41586-020-2246-4

Publications 2019

Hübner MP, Gunderson E, Vogel I, et al. Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models [published online ahead of print, 2019 Dec 10]. Int J Parasitol Drugs Drug Resist. 2019;12:18–27. doi:10.1016/j.ijpddr.2019.12.001

Publications 2014

Aldridge J.R., Vogel I.A. Macrophage biology and their activation by protozoan-derived glycosylphosphatidylinositol anchors and hemozoin. The Journal of Parasitology. 2014. 100(6):737-42.