Thibault Leray

  • PhD student; Msc
  • +47 22 78 23 18

HORIZON-MSCA (MELOMANES)

Education

2023 - Present: PhD Student in Department of Cellular Therapy, Oslo University Hospital, Norway - CAR and TCR-based immunotherapy development. Participation in the MELOMANES European Consortium: Universal CAR and T cell receptor-based combination therapy for melanoma treatment

2021 - 2022: Master’s degree in Immunology & Immunopathology, Paris University, Paris, France. Specialties: Immunology, immunotherapies, autoimmunity, tumor microenvironment

2020 - 2021: Master’s degree in Biology & Health, Ecole Normale Supérieure Paris-Saclay, Saclay, France. Specialties: Immunology, microbiology, cancerology, virology, bioinformatics

2019-2020: Bachelor’s degree in Biology & Health, Ecole Normale Supérieure Paris-Saclay, Saclay, France. Specialties: Molecular biology, cellular biology, genetics, physiology, bioinformatics

Professional experience 

October 2023 - Present: PhD Student in Department of Cellular Therapy, Oslo University Hospital, Norway - CAR and TCR immunotherapy development. Participation in the MELOMANES European Consortium: Universal CAR- and T cell receptor-based combination therapy for melanoma treatment

September 2022 - September 2023: Visiting Graduate Student, Tang Lab, Diabetes Center, University of California, San Francisco. Islet antigen specific TCR engineering of human regulatory T cells for the treatment of type 1 diabetes

January 2022 - July 2022: Intern, Innate Immunity Unit, Institut Pasteur, Paris, France. Optimization of human ILC in vitro expansion and genetic editing targeting ILC metabolic pathways for potential use in adoptive cell transfer therapies

August 2021 - October 2021: Laboratory technician, COVID Team, Eurofins Molecular Biology France, Nantes, France. RT-qPCR of nasopharyngeal human samples for SARS-Cov2 detection

June 2021 - August 2021: Intern, Immune Response and danger signals Unit, Institut Necker, Paris, France. Study of the regulation of STING signaling pathway through UNC93B1-STIM1 association

June 2020 - July 2020: Intern, Biology of Phagocytes, Infection and Immunity Unit, Institut Cochin, Paris, France. Characterization of HIV-1 and Chlamydia trachomatis co-infections’ impact in human macrophages

November 2019: Intern, Inflammation, chemokines and Immunopathology Unit, Inserm, Clamart, France. Study on the effect of the inhibition of communication junctions on the replication of a high-risk carcinogen human papillomavirus

Research Interest / Project

Test the combination of CAR-T cells and TCR-engineered T cells specific for melanoma tumor cells to enhance targeting and killing. 

Immunotherapy development - Tumor microenvironment disruption to enhance T cells penetration

 

 
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