Publications

Publications published since 2000 from OUS - Department of Pharmacology

563 publications found

Publications 2021

Azevedo C, Andersen JT, Traverso G, Sarmento B (2021)
The potential of porcine ex vivo platform for intestinal permeability screening of FcRn-targeted drugs
Eur J Pharm Biopharm, 162, 99-104
DOI 10.1016/j.ejpb.2021.03.009, PubMed 33771621
Barnes NM, Ahern GP, Becamel C, Bockaert J, Camilleri M, Chaumont-Dubel S, Claeysen S, Cunningham KA, Fone KC, Gershon M, Di Giovanni G, Goodfellow NM, Halberstadt AL, Hartley RM, Hassaine G, Herrick-Davis K, Hovius R, Lacivita E, Lambe EK, Leopoldo M, Levy FO, Lummis SCR, Marin P, Maroteaux L, McCreary AC et al. (2021)
International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
Pharmacol Rev, 73 (1), 310-520
DOI 10.1124/pr.118.015552, PubMed 33370241
Baumgartner T, Carreño M, Rocamora R, Bisulli F, Boni A, Brázdil M, Horak O, Craiu D, Pereira C, Guerrini R, San Antonio-Arce V, Schulze-Bonhage A, Zuberi SM, Hallböök T, Kalviainen R, Lagae L, Nguyen S, Quintas S, Franco A, Cross JH, Walker M, Arzimanoglou A, Rheims S, Granata T, Canafoglia L et al. (2021)
A survey of the European Reference Network EpiCARE on clinical practice for selected rare epilepsies
Epilepsia Open, 6 (1), 160-170
DOI 10.1002/epi4.12459, PubMed 33681659
Bergan S, Brunet M, Hesselink DA, Johnson-Davis KL, Kunicki PK, Lemaitre F, Marquet P, Molinaro M, Noceti O, Pattanaik S, Pawinski T, Seger C, Shipkova M, Swen JJ, van Gelder T, Venkataramanan R, Wieland E, Woillard JB, Zwart TC, Barten MJ, Budde K, Dieterlen MT, Elens L, Haufroid V, Masuda S et al. (2021)
Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology
Ther Drug Monit, 43 (2), 150-200
DOI 10.1097/FTD.0000000000000871, PubMed 33711005
Bjørnebekk A, Kaufmann T, Hauger LE, Klonteig S, Hullstein IR, Westlye LT (2021)
Long-term Anabolic-Androgenic Steroid Use Is Associated With Deviant Brain Aging
Biol Psychiatry Cogn Neurosci Neuroimaging (in press)
DOI 10.1016/j.bpsc.2021.01.001, PubMed 33811018
Brede C, Vethe NT, Skadberg Ø (2021)
The Question of Accuracy versus Interlaboratory Agreement for Monitoring the Immunosuppressants Everolimus and Sirolimus
Ther Drug Monit (in press)
DOI 10.1097/FTD.0000000000000892, PubMed 33840796
Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
Exercise Training Stabilizes RyR2-Dependent Ca²⁺ Release in Post-infarction Heart Failure
Front Cardiovasc Med, 7, 623922
DOI 10.3389/fcvm.2020.623922, PubMed 33569394
Høydahl LS, Frigstad T, Rasmussen IB, Øynebråten I, Schjetne KW, Andersen JT, Michaelsen TE, Lunde E, Bogen B, Sandlie I (2021)
Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses
Vaccine, 39 (11), 1583-1592
DOI 10.1016/j.vaccine.2021.02.012, PubMed 33612340
Johannessen Landmark C, Potschka H, Auvin S, Wilmshurst JM, Johannessen SI, Kasteleijn-Nolst Trenité D, Wirrell EC (2021)
The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results
Epilepsia, 62 (4), 857-873
DOI 10.1111/epi.16849, PubMed 33638459
Jorstad OK, Sivertsen MS, Andersen JT, Moe MC (2021)
Can the ampoules of covid-19 vaccine be used better?
Tidsskr. Nor. Laegeforen., 141 (2), 110
Klæstad E, Sawicka JE, Engstrøm MJ, Ytterhus B, Valla M, Bofin AM (2021)
ZNF703 gene copy number and protein expression in breast cancer; associations with proliferation, prognosis and luminal subtypes
Breast Cancer Res Treat, 186 (1), 65-77
DOI 10.1007/s10549-020-06035-0, PubMed 33389351
Midtlyng L, Høiseth G, Luytkis H, Kristoffersen L, Le Nygaard I, Strand MC, Arnestad M, Vevelstad M (2021)
Relationship between betahydroxybutyrate (BHB) and acetone concentrations in postmortem blood and cause of death
Forensic Sci Int, 321, 110726
DOI 10.1016/j.forsciint.2021.110726, PubMed 33631622
Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension
Blood Press, 30 (2), 82-89
DOI 10.1080/08037051.2020.1855968, PubMed 33403886
Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk
Blood Press, 30 (2), 90-97
DOI 10.1080/08037051.2020.1856642, PubMed 33403890
Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
Atherosclerosis (in press)
DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552
Rognstad S, Søraas CL, Bergland OU, Høieggen A, Strømmen M, Helland A, Opdal MS (2021)
Establishing Serum Reference Ranges for Antihypertensive Drugs
Ther Drug Monit, 43 (1), 116-125
DOI 10.1097/FTD.0000000000000806, PubMed 32881780
Solheim SA, Levernaes MCS, Mørkeberg J, Juul A, Upners EN, Nordsborg NB, Dehnes Y (2021)
Stability and detectability of testosterone esters in Dried Blood Spots after intramuscular injections
Drug Test Anal (in press)
DOI 10.1002/dta.3030, PubMed 33733610
Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2021)
Correction to: Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of highgrade pseudomyxoma peritonei
Clin Exp Metastasis, 38 (2), 253
DOI 10.1007/s10585-021-10084-0, PubMed 33649933

Publications 2020

Amrutkar M, Vethe NT, Verbeke CS, Aasrum M, Finstadsveen AV, Sántha P, Gladhaug IP (2020)
Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing
Cancers (Basel), 12 (12)
DOI 10.3390/cancers12123628, PubMed 33287390
Arzimanoglou A, Brandl U, Cross JH, Gil-Nagel A, Lagae L, Landmark CJ, Specchio N, Nabbout R, Thiele EA, Gubbay O, The Cannabinoids International Experts Panel, Collaborators (2020)
Epilepsy and cannabidiol: a guide to treatment
Epileptic Disord, 22 (1), 1-14
DOI 10.1684/epd.2020.1141, PubMed 32096470
Azevedo C, Nilsen J, Grevys A, Nunes R, Andersen JT, Sarmento B (2020)
Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin
J Control Release, 327, 161-173
DOI 10.1016/j.jconrel.2020.08.005, PubMed 32771477
Bejder J, Breenfeldt Andersen A, Bonne TC, Piil JF, Hagen LCH, Dehnes Y, Eibye KH, Nybo L, Nordsborg NB (2020)
Tramadol Does Not Improve Performance or Impair Motor Function in Trained Cyclists
Med Sci Sports Exerc, 52 (5), 1169-1175
DOI 10.1249/MSS.0000000000002217, PubMed 31809408
Bern M, Nilsen J, Ferrarese M, Sand KMK, Gjølberg TT, Lode HE, Davidson RJ, Camire RM, Bækkevold ES, Foss S, Grevys A, Dalhus B, Wilson J, Høydahl LS, Christianson GJ, Roopenian DC, Schlothauer T, Michaelsen TE, Moe MC, Lombardi S, Pinotti M, Sandlie I, Branchini A, Andersen JT (2020)
An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics
Sci Transl Med, 12 (565)
DOI 10.1126/scitranslmed.abb0580, PubMed 33055243
Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Perucca P, Tomson T, White HS (2020)
Progress report on new antiepileptic drugs: A summary of the Fifteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XV). II. Drugs in more advanced clinical development
Epilepsia, 61 (11), 2365-2385
DOI 10.1111/epi.16726, PubMed 33165915
Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Perucca P, Tomson T, White HS (2020)
Progress report on new antiepileptic drugs: A summary of the Fifteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XV). I. Drugs in preclinical and early clinical development
Epilepsia, 61 (11), 2340-2364
DOI 10.1111/epi.16725, PubMed 33190243
Caddy SL, Vaysburd M, Papa G, Wing M, O'Connell K, Stoycheva D, Foss S, Terje Andersen J, Oxenius A, James LC (2020)
Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
EMBO J, 40 (5), e106228
DOI 10.15252/embj.2020106228, PubMed 33258165
Caddy SL, Vaysburd M, Wing M, Foss S, Andersen JT, O'Connell K, Mayes K, Higginson K, Iturriza-Gómara M, Desselberger U, James LC (2020)
Intracellular neutralisation of rotavirus by VP6-specific IgG
PLoS Pathog, 16 (8), e1008732
DOI 10.1371/journal.ppat.1008732, PubMed 32750093
Crossland RE, Perutelli F, Bogunia-Kubik K, Mooney N, Milutin Gašperov N, Pučić-Baković M, Greinix H, Weber D, Holler E, Pulanić D, Wolff D, Dickinson AM, Inngjerdingen M, Grce M (2020)
Potential Novel Biomarkers in Chronic Graft-Versus-Host Disease
Front Immunol, 11, 602547
DOI 10.3389/fimmu.2020.602547, PubMed 33424849
Edwin TH, Henjum K, Nilsson LNG, Watne LO, Persson K, Eldholm RS, Saltvedt I, Halaas NB, Selbæk G, Engedal K, Strand BH, Knapskog AB (2020)
A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease
Alzheimers Dement (Amst), 12 (1), e12128
DOI 10.1002/dad2.12128, PubMed 33313376
Egeland EJ, Witczak BJ, Zaré HK, Christensen H, Åsberg A, Robertsen I (2020)
Chronic Inhibition of CYP3A is Temporarily Reduced by Each Hemodialysis Session in Patients With End-Stage Renal Disease
Clin Pharmacol Ther, 108 (4), 866-873
DOI 10.1002/cpt.1875, PubMed 32356565
Elens L, Langman LJ, Hesselink DA, Bergan S, Moes DJAR, Molinaro M, Venkataramanan R, Lemaitre F (2020)
Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug-Drug Interactions
Ther Drug Monit, 42 (3), 360-368
DOI 10.1097/FTD.0000000000000761, PubMed 32304488
Farcas M, Inngjerdingen M (2020)
Natural killer cell-derived extracellular vesicles in cancer therapy
Scand J Immunol, 92 (4), e12938
DOI 10.1111/sji.12938, PubMed 32697853
Franco V, Gatti G, Mazzucchelli I, Marchiselli R, Fattore C, Rota P, Galimberti CA, Capovilla G, Beccaria F, De Giorgis V, Johannessen Landmark C, Perucca E (2020)
Relationship between saliva and plasma rufinamide concentrations in patients with epilepsy
Epilepsia, 61 (7), e79-e84
DOI 10.1111/epi.16584, PubMed 32562438
Gustavsen MT, Midtvedt K, Robertsen I, Woillard JB, Debord J, Klaasen RA, Vethe NT, Bergan S, Åsberg A (2020)
Fasting Status and Circadian Variation Must be Considered When Performing AUC-based Therapeutic Drug Monitoring of Tacrolimus in Renal Transplant Recipients
Clin Transl Sci, 13 (6), 1327-1335
DOI 10.1111/cts.12833, PubMed 32652886
Gustavsen MT, Midtvedt K, Vethe NT, Robertsen I, Bergan S, Åsberg A (2020)
Tacrolimus Area Under the Concentration Versus Time Curve Monitoring, Using Home-Based Volumetric Absorptive Capillary Microsampling
Ther Drug Monit, 42 (3), 407-414
DOI 10.1097/FTD.0000000000000697, PubMed 31479042
Halaas NB, Henjum K, Blennow K, Dakhil S, Idland AV, Nilsson LN, Sederevicius D, Vidal-Piñeiro D, Walhovd KB, Wyller TB, Zetterberg H, Watne LO, Fjell AM (2020)
CSF sTREM2 and Tau Work Together in Predicting Increased Temporal Lobe Atrophy in Older Adults
Cereb Cortex, 30 (4), 2295-2306
DOI 10.1093/cercor/bhz240, PubMed 31812991
Heger K, Lund C, Larsen Burns M, Bjørnvold M, Sætre E, Johannessen SI, Johannessen Landmark C (2020)
A retrospective review of changes and challenges in the use of antiseizure medicines in Dravet syndrome in Norway
Epilepsia Open, 5 (3), 432-441
DOI 10.1002/epi4.12413, PubMed 32913951
Hemmersbach P (2020)
Mats Garle
Drug Test Anal, 12 (11-12), 1543
DOI 10.1002/dta.2922, PubMed 33006237
Henjum K, Årskog V, Jendresen CB, Fladby T, Torp R, Nilsson LNG (2020)
Analyzing microglial-associated Aβ in Alzheimer's disease transgenic mice with a novel mid-domain Aβ-antibody
Sci Rep, 10 (1), 10590
DOI 10.1038/s41598-020-67419-2, PubMed 32601313
Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P et al. (2020)
Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
Proc Natl Acad Sci U S A, 117 (40), 25018-25025
DOI 10.1073/pnas.2010540117, PubMed 32943538
Hubbard JJ, Pyzik M, Rath T, Kozicky LK, Sand KMK, Gandhi AK, Grevys A, Foss S, Menzies SC, Glickman JN, Fiebiger E, Roopenian DC, Sandlie I, Andersen JT, Sly LM, Baker K, Blumberg RS (2020)
FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity
J Exp Med, 217 (10)
DOI 10.1084/jem.20200359, PubMed 32658257
Jang W, Adams CE, Liu H, Zhang C, Levy FO, Andressen KW, Lambert NA (2020)
An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling
Proc Natl Acad Sci U S A, 117 (48), 30755-30762
DOI 10.1073/pnas.2010801117, PubMed 33199589
Jessen S, Becker V, Rzeppa S, Backer V, Bengtsen KH, Hullstein I, Dehnes Y, Hostrup M (2020)
Pharmacokinetics of salmeterol and its main metabolite α-hydroxysalmeterol after acute and chronic dry powder inhalation in exercising endurance-trained men: Implications for doping control
Drug Test Anal, 13 (4), 747-761
DOI 10.1002/dta.2978, PubMed 33210444
Johannessen Landmark C, Heger K, Lund C, Burns ML, Bjørnvold M, Sætre E, Johannessen SI (2020)
Pharmacokinetic Variability During Long-Term Therapeutic Drug Monitoring of Valproate, Clobazam, and Levetiracetam in Patients With Dravet Syndrome
Ther Drug Monit, 42 (5), 744-753
DOI 10.1097/FTD.0000000000000781, PubMed 32558674
Johannessen Landmark C, Johannessen SI, Patsalos PN (2020)
Therapeutic drug monitoring of antiepileptic drugs: current status and future prospects
Expert Opin Drug Metab Toxicol, 16 (3), 227-238
DOI 10.1080/17425255.2020.1724956, PubMed 32054370
Klaasen RA, Bergan S, Bremer S, Hole K, Nordahl CB, Andersen AM, Midtvedt K, Skauby MH, Vethe NT (2020)
Pharmacodynamic assessment of mycophenolic acid in resting and activated target cell population during the first year after renal transplantation
Br J Clin Pharmacol, 86 (6), 1100-1112
DOI 10.1111/bcp.14218, PubMed 31925806
Knapskog AB, Henjum K, Idland AV, Eldholm RS, Persson K, Saltvedt I, Watne LO, Engedal K, Nilsson LNG (2020)
Cerebrospinal fluid sTREM2 in Alzheimer's disease: comparisons between clinical presentation and AT classification
Sci Rep, 10 (1), 15886
DOI 10.1038/s41598-020-72878-8, PubMed 32985583
Kristiansen O, Vethe NT, Peersen K, Fagerland MW, Sverre E, Jensen EP, Lindberg M, Gjertsen E, Gullestad L, Perk J, Dammen T, Bergan S, Husebye E, Otterstad JE, Munkhaugen J (2020)
Effect of atorvastatin on muscle symptoms in coronary heart disease patients with self-perceived statin muscle side-effects: a randomized, double blinded crossover trial
Eur Heart J Cardiovasc Pharmacother (in press)
DOI 10.1093/ehjcvp/pvaa076, PubMed 32609361
Kvamsøe MM, Hansen KR, Skadberg Ø, Vethe NT, Brede C (2020)
Salting Out-Assisted Liquid-Liquid Extraction for Liquid Chromatography-Tandem Mass Spectrometry Measurement of Tacrolimus, Sirolimus, Everolimus, and Cyclosporine a in Whole Blood
Ther Drug Monit, 42 (5), 695-701
DOI 10.1097/FTD.0000000000000794, PubMed 32701594
Lang GP, Ndongson-Dongmo B, Lajqi T, Brodhun M, Han Y, Wetzker R, Frasch MG, Bauer R (2020)
Impact of ambient temperature on inflammation-induced encephalopathy in endotoxemic mice-role of phosphoinositide 3-kinase gamma
J Neuroinflammation, 17 (1), 292
DOI 10.1186/s12974-020-01954-7, PubMed 33028343
Lau C, McAdam MB, Bergseth G, Grevys A, Bruun JA, Ludviksen JK, Fure H, Espevik T, Moen A, Andersen JT, Mollnes TE (2020)
NHDL, a recombinant V_L/V_H hybrid antibody control for IgG2/4 antibodies
MAbs, 12 (1), 1686319
DOI 10.1080/19420862.2019.1686319, PubMed 31671278
Lemaitre F, Vethe NT, D'Avolio A, Tron C, Robertsen I, De Winter B, Denicolo A, Koch BCP, Venkataramanan R, Van Gelder T, Brunet M, Bergan S, Hesselink DA, Wallemacq P (2020)
Measuring Intracellular Concentrations of Calcineurin Inhibitors: Expert Consensus from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Expert Panel
Ther Drug Monit, 42 (5), 665-670
DOI 10.1097/FTD.0000000000000780, PubMed 32520841
Mullen J, Baekken LV, Törmäkangas T, Ekström L, Ericsson M, Hullstein IR, Schulze JJ (2020)
Inter-individual variation of the urinary steroid profiles in Swedish and Norwegian athletes
Drug Test Anal, 12 (6), 720-730
DOI 10.1002/dta.2778, PubMed 32052600
Neerland BE, Halaas NB, Idland AV, Henjum K, Blennow K, Zetterberg H, Watne LO (2020)
Fatty Acid-Binding Protein 3 in Cerebrospinal Fluid of Hip Fracture Patients with Delirium
J Alzheimers Dis, 77 (1), 183-190
DOI 10.3233/JAD-200364, PubMed 32804136
Saidu NEB, Bonini C, Dickinson A, Grce M, Inngjerdingen M, Koehl U, Toubert A, Zeiser R, Galimberti S (2020)
New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions
Front Immunol, 11, 578314
DOI 10.3389/fimmu.2020.578314, PubMed 33162993
Schrottmaier WC, Salzmann M, Badrnya S, Mussbacher M, Kral-Pointner JB, Morava S, Pirabe A, Brunnthaler L, Yaiw KC, Heber UM, Pereyra D, Andersen JT, Bergthaler A, Söderberg-Nauclér C, Karlsson MCI, Assinger A, Forsell MNE (2020)
Platelets mediate serological memory to neutralize viruses in vitro and in vivo
Blood Adv, 4 (16), 3971-3976
DOI 10.1182/bloodadvances.2020001786, PubMed 32841338
Solheim SA, Jessen S, Mørkeberg J, Thevis M, Dehnes Y, Eibye K, Hostrup M, Nordsborg NB (2020)
Single-dose administration of clenbuterol is detectable in dried blood spots
Drug Test Anal, 12 (9), 1366-1372
DOI 10.1002/dta.2872, PubMed 32495983
Solheim SA, Mørkeberg J, Dehnes Y, Hullstein I, Juul A, Upners EN, Nordsborg NB (2020)
Changes in blood parameters after intramuscular testosterone ester injections - Implications for anti-doping
Drug Test Anal, 12 (8), 1019-1030
DOI 10.1002/dta.2803, PubMed 32307878
Solheim SA, Mørkeberg J, Juul A, Freiesleben SY, Upners EN, Dehnes Y, Nordsborg NB (2020)
An Intramuscular Injection of Mixed Testosterone Esters Does Not Acutely Enhance Strength and Power in Recreationally Active Young Men
Front Physiol, 11, 563620
DOI 10.3389/fphys.2020.563620, PubMed 33071818
Svendsen T, Brodtkorb E, Baftiu A, Lossius MI, Nakken KO, Johannessen SI, Johannessen Landmark C (2020)
Clinical experience combined with therapeutic drug monitoring of lacosamide
Acta Neurol Scand, 141 (4), 279-286
DOI 10.1111/ane.13206, PubMed 31853958
Torp HA, Nystoyl B (2020)
Neutropenia in treatment with antipsychotics
Tidsskr. Nor. Laegeforen., 140 (8), 793-795
Tuv SS, Bjanes TK, Nordal K (2020)
Genotyping may cause fewer side effects with cancer treatment
Tidsskr. Nor. Laegeforen., 140 (15), 1530
Westergren T, Narum S, Klemp M (2020)
Adverse effects information in clinical guidelines on pharmacological treatment of depression in children and adolescents: a systematic review
BMJ Open, 10 (7), e036412
DOI 10.1136/bmjopen-2019-036412, PubMed 32690742

Publications 2019

Alvestad S, Bjørnvold M, Molteberg E, Lossius M, Landmark CJ (2019)
Continued importance of valproate for women with generalised epilepsy
Tidsskr Nor Laegeforen, 139 (7)
DOI 10.4045/tidsskr.19.0220, PubMed 30969058
Andreassen BK, Støer NC, Martinsen JI, Ursin G, Weiderpass E, Thoresen GH, Debernard KB, Karlstad Ø, Pottegard A, Friis S (2019)
Identification of potential carcinogenic and chemopreventive effects of prescription drugs: a protocol for a Norwegian registry-based study
BMJ Open, 9 (4), e028504
DOI 10.1136/bmjopen-2018-028504, PubMed 30962244
Baftiu A, Lima MH, Svendsen K, Larsson PG, Johannessen SI, Landmark CJ (2019)
Safety aspects of antiepileptic drugs-a population-based study of adverse effects relative to changes in utilisation
Eur J Clin Pharmacol, 75 (8), 1153-1160
DOI 10.1007/s00228-019-02678-1, PubMed 31001654
Bergström M, Müller M, Karlsson M, Scholz H, Vethe NT, Korsgren O (2019)
Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells
Cell Transplant, 28 (12), 1603-1613
DOI 10.1177/0963689719872488, PubMed 31512504
Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS (2019)
A summary of data presented at the XIV conference on new antiepileptic drug and devices (EILAT XIV)
Epilepsy Res, 153, 66-67
DOI 10.1016/j.eplepsyres.2019.03.002, PubMed 30910314
Blom KB, Bergo KK, Espe EKS, Rosseland V, Grøtta OJ, Mjøen G, Åsberg A, Bergan S, Sanner H, Bergersen TK, Bjørnerheim R, Skauby M, Seljeflot I, Waldum-Grevbo B, Dahle DO, Sjaastad I, Birkeland JA (2019)
Cardiovascular rEmodelling in living kidNey donorS with reduced glomerular filtration rate: rationale and design of the CENS study
Blood Press, 29 (2), 123-134
DOI 10.1080/08037051.2019.1684817, PubMed 31718316
Bottermann M, Foss S, Caddy SL, Clift D, van Tienen LM, Vaysburd M, Cruickshank J, O'Connell K, Clark J, Mayes K, Higginson K, Lode HE, McAdam MB, Sandlie I, Andersen JT, James LC (2019)
Complement C4 Prevents Viral Infection through Capsid Inactivation
Cell Host Microbe, 25 (4), 617-629.e7
DOI 10.1016/j.chom.2019.02.016, PubMed 30926239
Brunet M, van Gelder T, Åsberg A, Haufroid V, Hesselink DA, Langman L, Lemaitre F, Marquet P, Seger C, Shipkova M, Vinks A, Wallemacq P, Wieland E, Woillard JB, Barten MJ, Budde K, Colom H, Dieterlen MT, Elens L, Johnson-Davis KL, Kunicki PK, MacPhee I, Masuda S, Mathew BS, Millán O et al. (2019)
Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report
Ther Drug Monit, 41 (3), 261-307
DOI 10.1097/FTD.0000000000000640, PubMed 31045868
Bruun LD, Kjeldstadli K, Temte V, Birdal M, Bachs L, Langødegård M, Strand DH, Gaare KI, Øiestad E, Høiseth G (2019)
Detection Time of Oxazepam and Zopiclone in Urine and Oral Fluid after Experimental Oral Dosing
J Anal Toxicol, 43 (5), 369-377
DOI 10.1093/jat/bky083, PubMed 30615130
Bull Melsom C, Cosson MV, Ørstavik Ø, Lai NC, Hammond HK, Osnes JB, Skomedal T, Nikolaev V, Levy FO, Krobert KA (2019)
Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6
PLoS One, 14 (6), e0218110
DOI 10.1371/journal.pone.0218110, PubMed 31173603
Calamera G, Li D, Ulsund AH, Kim JJ, Neely OC, Moltzau LR, Bjørnerem M, Paterson D, Kim C, Levy FO, Andressen KW (2019)
FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons
Commun Biol, 2, 394
DOI 10.1038/s42003-019-0641-x, PubMed 31701023
Cosson MV, Hiis HG, Moltzau LR, Levy FO, Krobert KA (2019)
Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the β₁-adrenoceptor-mediated inotropic response
J Mol Cell Cardiol, 131, 132-145
DOI 10.1016/j.yjmcc.2019.04.017, PubMed 31009605
Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Carcas AJ, Borobia AM, Tong HY, Dávila-Fajardo C, Rodrigues Botton M, Bourgeois S, Deloukas P, Caldwell MD, Burmester JK, Berg RL, Cavallari LH, Drozda K, Huang M, Zhao LZ, Cen HJ, Gonzalez-Conejero R, Roldan V, Nakamura Y et al. (2019)
Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals
Clin Pharmacol Ther, 105 (6), 1477-1491
DOI 10.1002/cpt.1323, PubMed 30506689
Foss S, Bottermann M, Jonsson A, Sandlie I, James LC, Andersen JT (2019)
TRIM21-From Intracellular Immunity to Therapy
Front Immunol, 10, 2049
DOI 10.3389/fimmu.2019.02049, PubMed 31555278
Frost J, Bernard JP, Dietrichs ES, Kjeldstadli K, Riedel B, Skrastad RB, Vevelstad M, Helland A (2019)
New recommendations for serum concentration measurements of central stimulant drugs
Tidsskr. Nor. Laegeforen., 139 (13), 1230-1231
Granas AG, Halvorsen KH, Wendelbo J, Johannessen Landmark C (2019)
Interdisciplinary medication review to improve pharmacotherapy for patients with intellectual disabilities
Int J Clin Pharm, 41 (6), 1516-1525
DOI 10.1007/s11096-019-00914-3, PubMed 31729635
Havnen GC, Truong MB, Do MH, Heitmann K, Holst L, Nordeng H (2019)
Women's perspectives on the management and consequences of hyperemesis gravidarum - a descriptive interview study
Scand J Prim Health Care, 37 (1), 30-40
DOI 10.1080/02813432.2019.1569424, PubMed 30822254
Henning O, Johannessen Landmark C, Nakken KO, Lossius MI (2019)
Nonadherence to treatment regimens in epilepsy from the patient's perspective and predisposing factors: Differences between intentional and unintentional lack of adherence
Epilepsia, 60 (5), e58-e62
DOI 10.1111/epi.14734, PubMed 30980675
Henning O, Johannessen Landmark C, Traeen B, Svendsen T, Farmen A, Nakken KO, Lossius M (2019)
Sexual function in people with epilepsy: Similarities and differences with the general population
Epilepsia, 60 (9), 1984-1992
DOI 10.1111/epi.16311, PubMed 31407332
Henning O, Landmark CJ, Henning D, Nakken KO, Lossius MI (2019)
Challenges in epilepsy-The perspective of Norwegian epilepsy patients
Acta Neurol Scand, 140 (1), 40-47
DOI 10.1111/ane.13098, PubMed 30963535
Henning O, Lossius MI, Lima M, Mevåg M, Villagran A, Nakken KO, Johannessen Landmark C (2019)
Refractory epilepsy and nonadherence to drug treatment
Epilepsia Open, 4 (4), 618-623
DOI 10.1002/epi4.12367, PubMed 31819918
Jendresen C, Digre A, Cui H, Zhang X, Vlodavsky I, Li JP, Nilsson LNG (2019)
Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression
Sci Rep, 9 (1), 4600
DOI 10.1038/s41598-019-40999-4, PubMed 30872722
Johannessen Landmark C, Fløgstad I, Baftiu A, Syvertsen M, Enger U, Koht J, Johannessen SI (2019)
Long-term follow-up with therapeutic drug monitoring of antiepileptic drugs in patients with juvenile myoclonic epilepsy
Epilepsy Res, 155, 106148
DOI 10.1016/j.eplepsyres.2019.05.016, PubMed 31195184
Johannessen Landmark C, Fløgstad I, Syvertsen M, Baftiu A, Enger U, Koht J, Johannessen SI (2019)
Treatment and challenges with antiepileptic drugs in patients with juvenile myoclonic epilepsy
Epilepsy Behav, 98 (Pt A), 110-116
DOI 10.1016/j.yebeh.2019.05.021, PubMed 31330379
Klaasen RA, Egeland EJ, Chan J, Midtvedt K, Svensson M, Bolstad N, Fellström B, Holdaas H, Åsberg A, Bergan S, Vethe NT, Warren DJ (2019)
A Fully Automated Method for the Determination of Serum Belatacept and Its Application in a Pharmacokinetic Investigation in Renal Transplant Recipients
Ther Drug Monit, 41 (1), 11-18
DOI 10.1097/FTD.0000000000000580, PubMed 30633722
Kristiansen O, Vethe NT, Fagerland MW, Bergan S, Munkhaugen J, Husebye E (2019)
A novel direct method to determine adherence to atorvastatin therapy in patients with coronary heart disease
Br J Clin Pharmacol, 85 (12), 2878-2885
DOI 10.1111/bcp.14122, PubMed 31495943
Labzin LI, Bottermann M, Rodriguez-Silvestre P, Foss S, Andersen JT, Vaysburd M, Clift D, James LC (2019)
Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection
EMBO J, 38 (21), e101365
DOI 10.15252/embj.2018101365, PubMed 31468569
Larsen Burns M, Kinge E, Stokke Opdal M, Johannessen SI, Johannessen Landmark C (2019)
Therapeutic drug monitoring of gabapentin in various indications
Acta Neurol Scand, 139 (5), 446-454
DOI 10.1111/ane.13075, PubMed 30710348
Larsen Burns M, Nikanorova M, Baftiu A, Borg Rasmussen J, Johannessen SI, Johannessen Landmark C (2019)
Pharmacokinetic Variability and Clinical Use of Lacosamide in Children and Adolescents in Denmark and Norway
Ther Drug Monit, 41 (3), 340-347
DOI 10.1097/FTD.0000000000000599, PubMed 30688870
Lode HE, Gjølberg TT, Foss S, Sivertsen MS, Brustugun J, Andersson Y, Jørstad ØK, Moe MC, Andersen JT (2019)
A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes
Sci Rep, 9 (1), 18021
DOI 10.1038/s41598-019-54226-7, PubMed 31792234
Maaland AF, Heyerdahl H, O'Shea A, Eiriksdottir B, Pascal V, Andersen JT, Kolstad A, Dahle J (2019)
Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate ¹⁷⁷Lu-NNV003
Eur J Nucl Med Mol Imaging, 46 (11), 2311-2321
DOI 10.1007/s00259-019-04417-1, PubMed 31309259
Munkhaugen J, Vethe NT, Fagerland MW, Dammen T, Perk J, Gjertsen E, Otterstad JE, Gullestad L, Bergan S, Husebye E (2019)
Statin-associated muscle symptoms in coronary patients: design of a randomized study
Scand Cardiovasc J, 53 (3), 162-168
DOI 10.1080/14017431.2019.1612085, PubMed 31030568
Ndongson-Dongmo B, Lang GP, Mece O, Hechaichi N, Lajqi T, Hoyer D, Brodhun M, Heller R, Wetzker R, Franz M, Levy FO, Bauer R (2019)
Reduced ambient temperature exacerbates SIRS-induced cardiac autonomic dysregulation and myocardial dysfunction in mice
Basic Res Cardiol, 114 (3), 26
DOI 10.1007/s00395-019-0734-1, PubMed 31016449
Nordengen K, Kirsebom BE, Henjum K, Selnes P, Gísladóttir B, Wettergreen M, Torsetnes SB, Grøntvedt GR, Waterloo KK, Aarsland D, Nilsson LNG, Fladby T (2019)
Glial activation and inflammation along the Alzheimer's disease continuum
J Neuroinflammation, 16 (1), 46
DOI 10.1186/s12974-019-1399-2, PubMed 30791945
Pyzik M, Sand KMK, Hubbard JJ, Andersen JT, Sandlie I, Blumberg RS (2019)
The Neonatal Fc Receptor (FcRn): A Misnomer?
Front Immunol, 10, 1540
DOI 10.3389/fimmu.2019.01540, PubMed 31354709
Skulberg AK, Åsberg A, Khiabani HZ, Røstad H, Tylleskar I, Dale O (2019)
Pharmacokinetics of a novel, approved, 1.4-mg intranasal naloxone formulation for reversal of opioid overdose-a randomized controlled trial
Addiction, 114 (5), 859-867
DOI 10.1111/add.14552, PubMed 30644628
Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S (2019)
Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
Aging Cell, 18 (2), e12897
DOI 10.1111/acel.12897, PubMed 30712319
Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2019)
Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of high-grade pseudomyxoma peritonei
Clin Exp Metastasis, 36 (6), 511-518
DOI 10.1007/s10585-019-09991-0, PubMed 31541325
Temte V, Kjeldstadli K, Bruun LD, Birdal M, Bachs L, Karinen R, Middelkoop G, Øiestad E, Høiseth G (2019)
An Experimental Study of Diazepam and Alprazolam Kinetics in Urine and Oral Fluid Following Single Oral Doses
J Anal Toxicol, 43 (2), 104-111
DOI 10.1093/jat/bky062, PubMed 30517712
Traaen GM, Øverland B, Aakerøy L, Hunt TE, Bendz C, Sande L, Aakhus S, Zaré H, Steinshamn S, Anfinsen OG, Loennechen JP, Gullestad L, Akre H (2019)
Prevalence, risk factors, and type of sleep apnea in patients with paroxysmal atrial fibrillation
Int J Cardiol Heart Vasc, 26, 100447
DOI 10.1016/j.ijcha.2019.100447, PubMed 32140547
Tuv SS, Vethe NT, Bergan S, Nordal K (2019)
Pharmacogenetics in personalised drug therapy
Tidsskr. Nor. Laegeforen., 139 (8), 700-702
Vethe NT, Gustavsen MT, Midtvedt K, Lauritsen ME, Andersen AM, Åsberg A, Bergan S (2019)
Tacrolimus Can Be Reliably Measured With Volumetric Absorptive Capillary Microsampling Throughout the Dose Interval in Renal Transplant Recipients
Ther Drug Monit, 41 (5), 607-614
DOI 10.1097/FTD.0000000000000655, PubMed 31584926
Vethe NT, Munkhaugen J, Andersen AM, Husebye E, Bergan S (2019)
A Method for Direct Monitoring of Atorvastatin Adherence in Cardiovascular Disease Prevention: Quantification of the Total Exposure to Parent Drug and Major Metabolites Using 2-Channel Chromatography and Tandem Mass Spectrometry
Ther Drug Monit, 41 (1), 19-28
DOI 10.1097/FTD.0000000000000578, PubMed 30633723
Westergren T, Narum S, Klemp M (2019)
Critical appraisal of adverse effects reporting in the 'Treatment for Adolescents With Depression Study (TADS)'
BMJ Open, 9 (3), e026089
DOI 10.1136/bmjopen-2018-026089, PubMed 30878988

Publications 2018

Andressen KW, Ulsund AH, Krobert KA, Lohse MJ, Bünemann M, Levy FO (2018)
Related GPCRs couple differently to G_s: preassociation between G protein and 5-HT₇ serotonin receptor reveals movement of Gα_s upon receptor activation
FASEB J, 32 (2), 1059-1069
DOI 10.1096/fj.201700486R, PubMed 29079700
Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS (2018)
Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). II. Drugs in more advanced clinical development
Epilepsia, 59 (10), 1842-1866
DOI 10.1111/epi.14555, PubMed 30368788
Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS (2018)
Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development
Epilepsia, 59 (10), 1811-1841
DOI 10.1111/epi.14557, PubMed 30368792
Eek AK, Strøm BO, Bakkehøi G, Stenberg-Nilsen H (2018)
Anticoagulant-associated adverse drug reactions in 2013-15
Tidsskr Nor Laegeforen, 138 (12)
DOI 10.4045/tidsskr.17.0706, PubMed 30132616
Eide IA, Reinholt FP, Jenssen T, Hartmann A, Schmidt EB, Åsberg A, Bergan S, Brabrand K, Svensson M (2018)
Effects of marine n-3 fatty acid supplementation in renal transplantation: A randomized controlled trial
Am J Transplant, 19 (3), 790-800
DOI 10.1111/ajt.15080, PubMed 30125457
Fjeld H, Stylianou E (2018)
Hypersensitivity reactions with prolonged infusions of β-lactams?
Clin Microbiol Infect, 25 (1), 121-122
DOI 10.1016/j.cmi.2018.08.021, PubMed 30195470
Grevys A, Nilsen J, Sand KMK, Daba MB, Øynebråten I, Bern M, McAdam MB, Foss S, Schlothauer T, Michaelsen TE, Christianson GJ, Roopenian DC, Blumberg RS, Sandlie I, Andersen JT (2018)
A human endothelial cell-based recycling assay for screening of FcRn targeted molecules
Nat Commun, 9 (1), 621
DOI 10.1038/s41467-018-03061-x, PubMed 29434196
Havig SM, Lea D, Krpo M, Skari RM, Gustavsen I, Høiseth G (2018)
Fatal Adverse Event with Dabigatran in Elderly Patient with Reduced Kidney Function
Basic Clin Pharmacol Toxicol, 123 (2), 221-226
DOI 10.1111/bcpt.12985, PubMed 29438599
Heldal K, Midtvedt K, Hartmann A, Reisaeter AV, Heldal TF, Bergan S, Salvador CL, Åsberg A (2018)
Estimated glomerular filtration rate in stable older kidney transplant recipients-are present algorithms valid? A national cross-sectional cohort study
Transpl Int, 31 (6), 629-638
DOI 10.1111/tri.13137, PubMed 29453878
Henjum K, Quist-Paulsen E, Zetterberg H, Blennow K, Nilsson LNG, Watne LO (2018)
CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau
J Neuroinflammation, 15 (1), 304
DOI 10.1186/s12974-018-1331-1, PubMed 30390679
Hiis HG, Cosson MV, Dahl CP, Fiane AE, Levy FO, Andersen GØ, Krobert KA (2018)
Hypothermia elongates the contraction-relaxation cycle in explanted human failing heart decreasing the time for ventricular filling during diastole
Am J Physiol Heart Circ Physiol, 315 (5), H1137-H1147
DOI 10.1152/ajpheart.00208.2018, PubMed 30004809
Hov KR, Neerland BE, Andersen AM, Undseth Ø, Wyller VB, MacLullich AMJ, Skovlund E, Qvigstad E, Wyller TB (2018)
The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses
BMC Pharmacol Toxicol, 19 (1), 29
DOI 10.1186/s40360-018-0218-1, PubMed 29884231
Johannessen Landmark C, Farmen AH, Burns ML, Baftiu A, Lossius MI, Johannessen SI, Tomson T (2018)
Pharmacokinetic variability of valproate during pregnancy - Implications for the use of therapeutic drug monitoring
Epilepsy Res, 141, 31-37
DOI 10.1016/j.eplepsyres.2018.02.004, PubMed 29453075
Klaasen RA, Bergan S, Bremer S, Daleq L, Andersen AM, Midtvedt K, Skauby MH, Vethe NT (2018)
Longitudinal Study of Tacrolimus in Lymphocytes During the First Year After Kidney Transplantation
Ther Drug Monit, 40 (5), 558-566
DOI 10.1097/FTD.0000000000000539, PubMed 30086087
Krogstad V, Vethe NT, Robertsen I, Hasvold G, Ose AD, Hermann M, Andersen AM, Chan J, Skauby M, Svensson MHS, Åsberg A, Christensen H (2018)
Determination of Tacrolimus Concentration and Protein Expression of P-Glycoprotein in Single Human Renal Core Biopsies
Ther Drug Monit, 40 (3), 292-300
DOI 10.1097/FTD.0000000000000510, PubMed 29578937
Krug O, Thomas A, Malerød-Fjeld H, Dehnes Y, Laussmann T, Feldmann I, Sickmann A, Thevis M (2018)
Analysis of new growth promoting black market products
Growth Horm IGF Res, 41, 1-6
DOI 10.1016/j.ghir.2018.05.001, PubMed 29864719
Müller LD, Opdal MS (2018)
Developing a rapid semi-automated sample preparation with alkaline hydrolysis in a 96-well plate for quantification of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in urine samples by UHPLC-MS/MS
J Pharm Biomed Anal, 161, 296-304
DOI 10.1016/j.jpba.2018.08.045, PubMed 30189411
Munkhaugen J, Ruddox V, Halvorsen S, Dammen T, Fagerland MW, Hernæs KH, Vethe NT, Prescott E, Jensen SE, Rødevand O, Jortveit J, Bendz B, Schirmer H, Køber L, Bøtker HE, Larsen AI, Vikenes K, Steigen T, Wiseth R, Pedersen T, Edvardsen T, Otterstad JE, Atar D (2018)
BEtablocker Treatment After acute Myocardial Infarction in revascularized patients without reduced left ventricular ejection fraction (BETAMI): Rationale and design of a prospective, randomized, open, blinded end point study
Am Heart J, 208, 37-46
DOI 10.1016/j.ahj.2018.10.005, PubMed 30530121
Nilsen J, Sandlie I, Roopenian DC, Andersen JT (2018)
Animal models for evaluation of albumin-based therapeutics
Curr. Opin. Chem. Eng., 19, 68-76
Reimers A, Berg JA, Burns ML, Brodtkorb E, Johannessen SI, Johannessen Landmark C (2018)
Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines
Drug Des Devel Ther, 12, 271-280
DOI 10.2147/DDDT.S154388, PubMed 29467570
Reiter L, Stenberg-Nilsen H (2018)
Too high vitamin D content in dietary supplements?
Tidsskr. Nor. Laegeforen., 138 (1), 20-21
Serk TT, Le Nygaard I, Kvan E, Frost J, Aronsen L, Narum S, Bjanes T (2018)
Immediate telephonic alerting of deviating pharmacological test results
Tidsskr. Nor. Laegeforen., 138 (18), 1694-1695
Skogestad J, Aronsen JM (2018)
Hypokalemia-Induced Arrhythmias and Heart Failure: New Insights and Implications for Therapy
Front Physiol, 9, 1500
DOI 10.3389/fphys.2018.01500, PubMed 30464746
Stapleton NM, Armstrong-Fisher SS, Andersen JT, van der Schoot CE, Porter C, Page KR, Falconer D, de Haas M, Williamson LM, Clark MR, Vidarsson G, Armour KL (2018)
Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport
Mol Immunol, 95, 1-9
DOI 10.1016/j.molimm.2018.01.006, PubMed 29367080
Syvertsen M, Fløgstad I, Enger U, Landmark CJ, Koht J (2018)
Antiepileptic drug withdrawal in juvenile myoclonic epilepsy
Acta Neurol Scand, 139 (2), 192-198
DOI 10.1111/ane.13042, PubMed 30378684
Traaen GM, Aakerøy L, Hunt TE, Øverland B, Lyseggen E, Aukrust P, Ueland T, Helle-Valle T, Steinshamn S, Edvardsen T, Khiabani Zaré H, Aakhus S, Akre H, Anfinsen OG, Loennechen JP, Gullestad L (2018)
Treatment of sleep apnea in patients with paroxysmal atrial fibrillation: design and rationale of a randomized controlled trial
Scand Cardiovasc J, 52 (6), 372-377
DOI 10.1080/14017431.2019.1567933, PubMed 30638392
Tvete IF, Bjørner T, Skomedal T (2018)
Mental Health and Disability Pension Onset: Changes in Consumption of Antianxiety and Hypnotic Drugs
Health Serv Res Manag Epidemiol, 5, 2333392818792683
DOI 10.1177/2333392818792683, PubMed 30182036

Publications 2017

Ahamed M, Vermeulen K, Schnekenburger M, Moltzau LR, Levy FO, Marton J, Froeyen M, Olberg DE, Diederich M, Bormans G (2017)
Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorinated Bioisosteres of Santacruzamate A as Potential HDAC Tracers
Lett. Drug Des. Discov., 14 (7), 787-797
Ask IS, Føreid S, Knatten CK, Wallace SC, Gadeholt G (2017)
[Detection of nitromethane in blood]
Tidsskr Nor Laegeforen, 137 (2), 112
DOI 10.4045/tidsskr.16.0100, PubMed 28127074
Baftiu A, Feet SA, Larsson PG, Burns ML, Henning O, Sætre E, Molden E, Granas AG, Johannessen SI, Landmark CJ (2017)
Utilisation and polypharmacy aspects of antiepileptic drugs in elderly versus younger patients with epilepsy: A pharmacoepidemiological study of CNS-active drugs in Norway, 2004-2015
Epilepsy Res, 139, 35-42
DOI 10.1016/j.eplepsyres.2017.11.001, PubMed 29175562
Baftiu A, Landmark CJ, Rusten IR, Feet SA, Johannessen SI, Larsson PG (2017)
Erratum to: Changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders-A pharmacoepidemiological study and clinical implications
Eur J Clin Pharmacol, 73 (6), 791-792
DOI 10.1007/s00228-017-2252-0, PubMed 28389679
Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS (2017)
Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII)
Epilepsia, 58 (2), 181-221
DOI 10.1111/epi.13634, PubMed 28111749
Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS, Koepp MJ (2017)
Seizure detection and neuromodulation: A summary of data presented at the XIII conference on new antiepileptic drug and devices (EILAT XIII)
Epilepsy Res, 130, 27-36
DOI 10.1016/j.eplepsyres.2017.01.004, PubMed 28113141
Bremer S, Vethe NT, Skauby M, Kasbo M, Johansson ED, Midtvedt K, Bergan S (2017)
NFAT-regulated cytokine gene expression during tacrolimus therapy early after renal transplantation
Br J Clin Pharmacol, 83 (11), 2494-2502
DOI 10.1111/bcp.13367, PubMed 28686294
Burns ML, Lang AM (2017)
The authors reply
Pediatr Crit Care Med, 18 (1), 98
DOI 10.1097/PCC.0000000000001023, PubMed 28060165
Eek AK, Øie E, Granas AG (2017)
Prescribing of NOACs has outnumbered warfarin: exploring how physicians choose anticoagulant treatments
Eur J Clin Pharmacol, 74 (3), 323-330
DOI 10.1007/s00228-017-2374-4, PubMed 29149366
Egeland EJ, Robertsen I, Hermann M, Midtvedt K, Størset E, Gustavsen MT, Reisæter AV, Klaasen R, Bergan S, Holdaas H, Hartmann A, Åsberg A (2017)
High Tacrolimus Clearance Is a Risk Factor for Acute Rejection in the Early Phase After Renal Transplantation
Transplantation, 101 (8), e273-e279
DOI 10.1097/TP.0000000000001796, PubMed 28452920
Føreid S, Gadeholt G (2017)
Beta-hydroxybutyrate and pyroglutamate can be included in a rapid GC-MS screening method for differential diagnosis of metabolic acidosis
Scand J Clin Lab Invest, 77 (2), 149-152
DOI 10.1080/00365513.2016.1278261, PubMed 28150506
Havig SM, Høiseth G, Strand MC, Karinen RA, Brochmann GW, Strand DH, Bachs L, Vindenes V (2017)
THC and CBD in blood samples and seizures in Norway: Does CBD affect THC-induced impairment in apprehended subjects?
Forensic Sci Int, 276, 12-17
DOI 10.1016/j.forsciint.2017.04.006, PubMed 28463706
Hjelmeland K, Gustavsen I, Øiestad EL, Øiestad ÅML, Høiseth G, Mørland J (2017)
Zopiclone concentrations in oral fluid and blood after, administration of therapeutic doses of zopiclone
Forensic Sci Int, 278, 177-183
DOI 10.1016/j.forsciint.2017.07.004, PubMed 28735217
Jendresen C, Årskog V, Daws MR, Nilsson LN (2017)
The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway
J Neuroinflammation, 14 (1), 59
DOI 10.1186/s12974-017-0835-4, PubMed 28320424
Jendresen C, Daws MR, Nilsson LNG (2017)
An improved CPRG colorimetric ligand-receptor signal transduction assay based on beta-galactosidase activity in mammalian BWZ-reporter cells
J Pharmacol Toxicol Methods, 90, 67-75
DOI 10.1016/j.vascn.2017.11.004, PubMed 29203451
Johannessen Landmark C, Burns ML, Baftiu A, Farmen AH, Lossius MI, Johannessen SI, Tomson T (2017)
Pharmacokinetic variability of valproate in women of childbearing age
Epilepsia, 58 (10), e142-e146
DOI 10.1111/epi.13872, PubMed 28833045
Krogh N, Rzeppa S, Dyreborg A, Dehnes Y, Hemmersbach P, Backer V, Hostrup M (2017)
Terbutaline Accumulates in Blood and Urine after Daily Therapeutic Inhalation
Med Sci Sports Exerc, 49 (6), 1236-1243
DOI 10.1249/MSS.0000000000001199, PubMed 28072631
Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
Eur J Pharmacol, 812, 174-183
DOI 10.1016/j.ejphar.2017.07.014, PubMed 28697992
Midtvedt K, Bergan S, Reisæter AV, Vikse BE, Åsberg A (2017)
Exposure to Mycophenolate and Fatherhood
Transplantation, 101 (7), e214-e217
DOI 10.1097/TP.0000000000001747, PubMed 28346297
Midtvedt K, Holdaas H, Bergan S, Åsberg A (2017)
Costimulation Blockade: America First, Canada Second … What About Norway?
Am J Transplant, 17 (8), 2230
DOI 10.1111/ajt.14351, PubMed 28508535
Ødegård J, Sondresen JE, Aasrum M, Tveteraas IH, Guren TK, Christoffersen T, Thoresen GH (2017)
Differential effects of epidermal growth factor (EGF) receptor ligands on receptor binding, downstream signalling pathways and DNA synthesis in hepatocytes
Growth Factors, 35 (6), 239-248
DOI 10.1080/08977194.2018.1453506, PubMed 29582692
Pisani LR, Nikanorova M, Landmark CJ, Johannessen SI, Pisani F (2017)
Specific Patient Features Affect Antiepileptic Drug Therapy Decisions: Focus on Gender, Age, and Psychiatric Comorbidities
Curr Pharm Des, 23 (37), 5639-5648
DOI 10.2174/1381612823666170926103631, PubMed 28950817
Pitarch-Motellón J, Roig-Navarro AF, Sancho JV, Ibáñez M, Fabregat-Cabello N, Pozo OJ, Ventura R, García Alonso JI, Rodríguez-González P, González Gago A, Ereño Artabe A, Van Eenoo P, Deventer K, Dehnes Y, Rzeppa S (2017)
Evaluation of uncertainty sources in the determination of testosterone in urine by calibration-based and isotope dilution quantification using ultra high performance liquid chromatography tandem mass spectrometry
J Chromatogr A, 1508, 73-80
DOI 10.1016/j.chroma.2017.05.072, PubMed 28601363
Raeder J, Dahl V, Markestad A, Nordbo A, Roaldset AH, Stubhaug A, Soeberg B, Willke A, Aasbo V, Johansen PW (2017)
From ketobemidone to morphine or oxycodone
Tidsskr. Nor. Laegeforen., 137 (3), 170
Reimers A, Berg JA, Burns ML, Landmark CJ (2017)
Harmonised reference ranges for antiepileptic drugs
Tidsskr Nor Laegeforen, 137 (12-13), 864-865
DOI 10.4045/tidsskr.17.0392, PubMed 28655236
Reimers A, Berg JA, Burns ML, Landmark CJ (2017)
Common reference range for antiepileptics
Tidsskr. Nor. Laegeforen., 137 (12-13), 864-865
Salvador CL, Hartmann A, Åsberg A, Bergan S, Rowe AD, Mørkrid L (2017)
Estimating Glomerular Filtration Rate in Kidney Transplant Recipients: Comparing a Novel Equation With Commonly Used Equations in this Population
Transplant Direct, 3 (12), e332
DOI 10.1097/TXD.0000000000000742, PubMed 29536033
Skauby RH, Bjerre A, Sæves I, Vethe NT, Bremer S, Svarstad A, Bergan S (2017)
Prednisolone and Prednisone Pharmacokinetics in Pediatric Renal Transplant Recipients-A Prospective Study
Ther Drug Monit, 39 (5), 472-482
DOI 10.1097/FTD.0000000000000439, PubMed 28749817
Størset E, Hole K, Midtvedt K, Bergan S, Molden E, Åsberg A (2017)
Response to: 'Response to: Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'
Br J Clin Pharmacol, 83 (6), 1357-1358
DOI 10.1111/bcp.13276, PubMed 28374426
Størset E, Hole K, Midtvedt K, Bergan S, Molden E, Åsberg A (2017)
The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation
Br J Clin Pharmacol, 83 (7), 1457-1465
DOI 10.1111/bcp.13248, PubMed 28146606
Strand TE, Khiabani HZ, Boico A, Radiloff D, Zhao Y, Hamilton KL, Christians U, Klawitter J, Noveck RJ, Piantadosi CA, Bell C, Irwin D, Schroeder T (2017)
The novel combination of theophylline and bambuterol as a potential treatment of hypoxemia in humans
Can J Physiol Pharmacol, 95 (9), 1009-1018
DOI 10.1139/cjpp-2016-0635, PubMed 28467859
Svendsen T, Brodtkorb E, Baftiu A, Burns ML, Johannessen SI, Johannessen Landmark C (2017)
Therapeutic Drug Monitoring of Lacosamide in Norway: Focus on Pharmacokinetic Variability, Efficacy and Tolerability
Neurochem Res, 42 (7), 2077-2083
DOI 10.1007/s11064-017-2234-8, PubMed 28349359
Torp HA, Gustavsen I, Romundstad L (2017)
A botanical anesthesia
Tidsskr. Nor. Laegeforen., 137 (23-24), 1924-1928
Torp HA, Gustavsen I, Romundstad L (2017)
[A botanical anesthesia]
Tidsskr Nor Laegeforen, 137 (23-24)
DOI 10.4045/tidsskr.17.0659, PubMed 29231661
Westergren T, Debernard KA (2017)
Discrepancies in paper by Chiam et al.: The haemodynamic effects of intravenous paracetamol
Br J Clin Pharmacol, 83 (2), 435
DOI 10.1111/bcp.13182, PubMed 28090696
Westergren T, Narum S, Klemp M (2017)
Characterization of gastrointestinal adverse effects reported in clinical studies of corticosteroid therapy
J Clin Epidemiol, 94, 19-26
DOI 10.1016/j.jclinepi.2017.10.018, PubMed 29113937

Publications 2016

Aasrum M, Brusevold IJ, Christoffersen T, Thoresen GH (2016)
HGF-induced DNA synthesis in hepatocytes is suppressed by p38
Growth Factors, 34 (5-6), 217-223
DOI 10.1080/08977194.2017.1285765, PubMed 28209091
Åstrand OAH, Viktorsson EÖ, Kristensen AL, Ekeberg D, Røberg-Larsen H, Wilson SR, Gabrielsen M, Sylte I, Rustan AC, Thoresen GH, Rongved P, Kase ET (2016)
Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors
J Steroid Biochem Mol Biol, 165 (Pt B), 323-330
DOI 10.1016/j.jsbmb.2016.07.010, PubMed 27471149
Baftiu A, Johannessen Landmark C, Rusten IR, Feet SA, Johannessen SI, Larsson PG (2016)
Changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders-a pharmacoepidemiological study and clinical implications
Eur J Clin Pharmacol, 72 (10), 1245-1254
DOI 10.1007/s00228-016-2092-3, PubMed 27411937
Bjørnebekk A, Walhovd KB, Jørstad ML, Due-Tønnessen P, Hullstein IR, Fjell AM (2016)
Structural Brain Imaging of Long-Term Anabolic-Androgenic Steroid Users and Nonusing Weightlifters
Biol Psychiatry, 82 (4), 294-302
DOI 10.1016/j.biopsych.2016.06.017, PubMed 27616036
Braadland PR, Grytli HH, Ramberg H, Katz B, Kellman R, Gauthier-Landry L, Fazli L, Krobert KA, Wang W, Levy FO, Bjartell A, Berge V, Rennie PS, Mellgren G, Mælandsmo GM, Svindland A, Barbier O, Taskén KA (2016)
Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism
Oncotarget, 7 (2), 1878-94
DOI 10.18632/oncotarget.6479, PubMed 26646591
Brunet M, Shipkova M, van Gelder T, Wieland E, Sommerer C, Budde K, Haufroid V, Christians U, López-Hoyos M, Barten MJ, Bergan S, Picard N, Millán López O, Marquet P, Hesselink DA, Noceti O, Pawinski T, Wallemacq P, Oellerich M (2016)
Barcelona Consensus on Biomarker-Based Immunosuppressive Drugs Management in Solid Organ Transplantation
Ther Drug Monit, 38 Suppl 1, S1-20
DOI 10.1097/FTD.0000000000000287, PubMed 26977997
Burns ML, Baftiu A, Opdal MS, Johannessen SI, Landmark CJ (2016)
Therapeutic Drug Monitoring of Clobazam and Its Metabolite-Impact of Age and Comedication on Pharmacokinetic Variability
Ther Drug Monit, 38 (3), 350-7
DOI 10.1097/FTD.0000000000000272, PubMed 26751267
Burns ML, Stensvold HJ, Risnes K, Guthe HJ, Astrup H, Nordhov SM, Selberg TR, Rønnestad A, Lang AM, Norwegian Neonatal Network (2016)
Inotropic Therapy in Newborns, A Population-Based National Registry Study
Pediatr Crit Care Med, 17 (10), 948-956
DOI 10.1097/PCC.0000000000000898, PubMed 27500723
Damkier P, Passier A, Bo Petersen L, Havnen G, Thestrup Pedersen AJ (2016)
Changing of the guards: EMA warning on paternal use of mycophenolate mofetil: An unnecessary and insufficiently substantiated precaution
Birth Defects Res A Clin Mol Teratol, 106 (10), 860-861
DOI 10.1002/bdra.23556, PubMed 27678452
Dyreborg A, Krogh N, Backer V, Rzeppa S, Hemmersbach P, Hostrup M (2016)
Pharmacokinetics of Oral and Inhaled Terbutaline after Exercise in Trained Men
Front Pharmacol, 7, 150
DOI 10.3389/fphar.2016.00150, PubMed 27375484
Eikemo H, Moltzau LR, Hussain RI, Nguyen CH, Qvigstad E, Levy FO, Skomedal T, Osnes JB (2016)
CaMKII in addition to MLCK contributes to phosphorylation of regulatory light chain in cardiomyocytes
Biochem Biophys Res Commun, 471 (1), 219-25
DOI 10.1016/j.bbrc.2016.01.132, PubMed 26809094
Eikemo H, Moltzau LR, Nguyen CHT, Levy FO, Skomedal T, Osnes JB (2016)
CaMKII and at least two unidentified kinases phosphorylate regulatory light chain in non-contracting cardiomyocytes
Biochem Biophys Res Commun, 477 (1), 14-19
DOI 10.1016/j.bbrc.2016.05.138, PubMed 27237977
Gottås A, Arnestad M, Halvorsen PS, Bachs LC, Høiseth G (2016)
Pharmacokinetics of heroin and its metabolites in vitreous humor and blood in a living pig model
Forensic Toxicol, 34 (2), 277-285
DOI 10.1007/s11419-016-0315-z, PubMed 27660664
Haga C, Opdal MS, Tuv SS, Zahl PH, Stenberg-Nilsen H (2016)
[Drug safety associated with the change of digitalis drug in Norway]
Tidsskr Nor Laegeforen, 136 (20), 1714-1718
DOI 10.4045/tidsskr.15.0161, PubMed 27830905
Halden TA, Egeland EJ, Åsberg A, Hartmann A, Midtvedt K, Khiabani HZ, Holst JJ, Knop FK, Hornum M, Feldt-Rasmussen B, Jenssen T (2016)
GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes
Diabetes Care, 39 (4), 617-24
DOI 10.2337/dc15-2383, PubMed 26908914
Heitmann K, Havnen GC, Holst L, Nordeng H (2016)
Pregnancy outcomes after prenatal exposure to echinacea: the Norwegian Mother and Child Cohort Study
Eur J Clin Pharmacol, 72 (5), 623-30
DOI 10.1007/s00228-016-2021-5, PubMed 26895223
Heitmann K, Solheimsnes A, Havnen GC, Nordeng H, Holst L (2016)
Treatment of nausea and vomiting during pregnancy -a cross-sectional study among 712 Norwegian women
Eur J Clin Pharmacol, 72 (5), 593-604
DOI 10.1007/s00228-016-2012-6, PubMed 26815908
Helland A, Berg JA, Gustavsen I, Nordal K, Hilberg T, Aronsen L, Arnestad M, Narum S (2016)
Serum concentration measurements of addictive drugs
Tidsskr Nor Laegeforen, 136 (5), 400-2
DOI 10.4045/tidsskr.16.0030, PubMed 26983140
Henjum K, Almdahl IS, Årskog V, Minthon L, Hansson O, Fladby T, Nilsson LN (2016)
Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease
Alzheimers Res Ther, 8 (1), 17
DOI 10.1186/s13195-016-0182-1, PubMed 27121148
Johannessen Landmark C, Henning O, Johannessen SI (2016)
Proconvulsant effects of antidepressants - What is the current evidence?
Epilepsy Behav, 61, 287-291
DOI 10.1016/j.yebeh.2016.01.029, PubMed 26926001
Johannessen Landmark C, Svendsen T, Dinarevic J, Kufaas RF, Reimers A, Brodtkorb E, Baftiu A, Burns ML, Johannessen SI (2016)
The Impact of Pharmacokinetic Interactions With Eslicarbazepine Acetate Versus Oxcarbazepine and Carbamazepine in Clinical Practice
Ther Drug Monit, 38 (4), 499-505
DOI 10.1097/FTD.0000000000000306, PubMed 27414974
Kloster-Jensen K, Sahraoui A, Vethe NT, Korsgren O, Bergan S, Foss A, Scholz H (2016)
Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids
J Diabetes Res, 2016, 4196460
DOI 10.1155/2016/4196460, PubMed 26885529
Kong XY, Feng YZ, Eftestøl E, Kase ET, Haugum H, Eskild W, Rustan AC, Thoresen GH (2016)
Increased glucose utilization and decreased fatty acid metabolism in myotubes from Glmp(gt/gt) mice
Arch Physiol Biochem, 122 (1), 36-45
DOI 10.3109/13813455.2015.1120752, PubMed 26707125
Kreiberg M, Becker V, Jessen S, Rzeppa S, Hemmersbach P, Backer V, Hostrup M (2016)
Influence of exercise in normal and hot ambient conditions on the pharmacokinetics of inhaled terbutaline in trained men
Scand J Med Sci Sports, 27 (7), 692-703
DOI 10.1111/sms.12697, PubMed 27167471
Krogh N, Backer V, Rzeppa S, Hemmersbach P, Hostrup M (2016)
Pharmacokinetics of nebulized and oral procaterol in asthmatic and non-asthmatic subjects in relation to doping analysis
Drug Test Anal, 8 (10), 1056-1064
DOI 10.1002/dta.1935, PubMed 26990656
Landmark CJ, Johannessen SI, Tomson T (2016)
Dosing strategies for antiepileptic drugs: from a standard dose for all to individualised treatment by implementation of therapeutic drug monitoring
Epileptic Disord, 18 (4), 367-383
DOI 10.1684/epd.2016.0880, PubMed 27965183
Lund J, Stensrud C, Rajender, Bohov P, Thoresen GH, Berge RK, Wright M, Kamal A, Rustan AC, Miller AD, Skorve J (2016)
The molecular structure of thio-ether fatty acids influences PPAR-dependent regulation of lipid metabolism
Bioorg Med Chem, 24 (6), 1191-203
DOI 10.1016/j.bmc.2016.01.045, PubMed 26874397
Mevaag M, Henning O, Baftiu A, Granas AG, Johannessen SI, Nakken KO, Johannessen Landmark C (2016)
Discrepancies between physicians' prescriptions and patients' use of antiepileptic drugs
Acta Neurol Scand, 135 (1), 80-87
DOI 10.1111/ane.12578, PubMed 26923477
Moen B, Henjum K, Måge I, Knutsen SH, Rud I, Hetland RB, Paulsen JE (2016)
Effect of Dietary Fibers on Cecal Microbiota and Intestinal Tumorigenesis in Azoxymethane Treated A/J Min/+ Mice
PLoS One, 11 (5), e0155402
DOI 10.1371/journal.pone.0155402, PubMed 27196124
Narum S, Brørs O, Stokland O, Kringen MK (2016)
Mortality among head trauma patients taking preinjury antithrombotic agents: a retrospective cohort analysis from a Level 1 trauma centre
BMC Emerg Med, 16 (1), 29
DOI 10.1186/s12873-016-0094-1, PubMed 27485307
Norum HM, Kolberg ES, Solhaug V, Nordal K, Aukrust P (2016)
Rhabdomyolysis and capillary leak syndrome in a patient treated with topical imiquimod
Int J Dermatol, 55 (9), 1030-2
DOI 10.1111/ijd.13255, PubMed 27061736
Olberg DE, Bauer N, Andressen KW, Hjørnevik T, Cumming P, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL (2016)
Brain penetrant small molecule (18)F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats
Nucl Med Biol, 43 (8), 478-89
DOI 10.1016/j.nucmedbio.2016.05.003, PubMed 27236283
Picard N, Bergan S, Marquet P, van Gelder T, Wallemacq P, Hesselink DA, Haufroid V (2016)
Pharmacogenetic Biomarkers Predictive of the Pharmacokinetics and Pharmacodynamics of Immunosuppressive Drugs
Ther Drug Monit, 38 Suppl 1, S57-69
DOI 10.1097/FTD.0000000000000255, PubMed 26469711
Rzeppa S, Viet L (2016)
Analysis of sulfate metabolites of the doping agents oxandrolone and danazol using high performance liquid chromatography coupled to tandem mass spectrometry
J Chromatogr B Analyt Technol Biomed Life Sci, 1029-1030, 1-9
DOI 10.1016/j.jchromb.2016.06.028, PubMed 27394004
Rzeppa S, Viet LN (2016)
Analysis of tolvaptan and its metabolites in sports drug testing by high-performance liquid chromatography coupled to tandem mass spectrometry
Drug Test Anal, 8 (10), 1090-1094
DOI 10.1002/dta.1933, PubMed 26768215
Sakshaug S, Handal M, Hjellvik V, Berg C, Ripel Å, Gustavsen I, Mørland J, Skurtveit S (2016)
Long-term Use of Z-Hypnotics and Co-medication with Benzodiazepines and Opioids
Basic Clin Pharmacol Toxicol, 120 (3), 292-298
DOI 10.1111/bcpt.12684, PubMed 27717229
Størset E, Åsberg A, Hartmann A, Reisaeter AV, Holdaas H, Skauby M, Bergan S, Midtvedt K (2016)
Low-target tacrolimus in de novo standard risk renal transplant recipients: A single-centre experience
Nephrology (Carlton), 21 (10), 821-7
DOI 10.1111/nep.12738, PubMed 26854648
Størset E, Hole K, Midtvedt K, Bergan S, Molden E, Åsberg A (2016)
Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance
Br J Clin Pharmacol, 83 (6), 1350-1352
DOI 10.1111/bcp.13188, PubMed 28008657
Størset E, von Düring ME, Godang K, Bergan S, Midtvedt K, Åsberg A (2016)
Prediction of Fat-Free Mass in Kidney Transplant Recipients
Ther Drug Monit, 38 (4), 439-46
DOI 10.1097/FTD.0000000000000305, PubMed 27019101
Svendsen T, Brodtkorb E, Reimers A, Molden E, Sætre E, Johannessen SI, Johannessen Landmark C (2016)
Pharmacokinetic variability, efficacy and tolerability of eslicarbazepine acetate-A national approach to the evaluation of therapeutic drug monitoring data and clinical outcome
Epilepsy Res, 129, 125-131
DOI 10.1016/j.eplepsyres.2016.12.001, PubMed 28043062
Tekpli X, Urbanucci A, Hashim A, Vågbø CB, Lyle R, Kringen MK, Staff AC, Dybedal I, Mills IG, Klungland A, Staerk J (2016)
Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
Epigenetics Chromatin, 9, 21
DOI 10.1186/s13072-016-0070-8, PubMed 27252783
Tuv SS, Krabseth HM, Strand MC, Karinen RA, Wiik E, Vevelstad MS, Westin AA, Øiestad EL, Vindenes V (2016)
New designer drugs from the web
Tidsskr Nor Laegeforen, 136 (8), 721-3
DOI 10.4045/tidsskr.15.1276, PubMed 27143463
Villar IC, Bubb KJ, Moyes AJ, Steiness E, Gulbrandsen T, Levy FO, Hobbs AJ (2016)
Functional pharmacological characterization of SER100 in cardiovascular health and disease
Br J Pharmacol, 173 (23), 3386-3401
DOI 10.1111/bph.13634, PubMed 27667485
Westlye LT, Kaufmann T, Alnæs D, Hullstein IR, Bjørnebekk A (2016)
Brain connectivity aberrations in anabolic-androgenic steroid users
Neuroimage Clin, 13, 62-69
DOI 10.1016/j.nicl.2016.11.014, PubMed 27942448

Publications 2015

Aasrum M, Ødegård J, Thoresen GH, Brusevold IJ, Sandnes DL, Christoffersen T (2015)
Gab1 amplifies signaling in response to low-intensity stimulation by HGF
Cell Biol Int, 39 (10), 1177-84
DOI 10.1002/cbin.10511, PubMed 26146811
Aasrum M, Tjomsland V, Thoresen GH, De Angelis PM, Christoffersen T, Brusevold IJ (2015)
PI3K is required for both basal and LPA-induced DNA synthesis in oral carcinoma cells
J Oral Pathol Med, 45 (6), 425-32
DOI 10.1111/jop.12384, PubMed 26602326
Baftiu A, Johannessen Landmark C, Nikaj V, Neslein IL, Johannessen SI, Perucca E (2015)
Availability of antiepileptic drugs across Europe
Epilepsia, 56 (12), e191-7
DOI 10.1111/epi.13210, PubMed 26477534
Bakke SS, Feng YZ, Nikolić N, Kase ET, Moro C, Stensrud C, Damlien L, Ludahl MO, Sandbu R, Solheim BM, Rustan AC, Hjelmesæth J, Thoresen GH, Aas V (2015)
Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects
PLoS One, 10 (3), e0119556
DOI 10.1371/journal.pone.0119556, PubMed 25790476
Beiske GA, Holmøy T, Beiske AG, Johannessen SI, Johannessen Landmark C (2015)
Antiepileptic and Antidepressive Polypharmacy in Patients with Multiple Sclerosis
Mult Scler Int, 2015, 317859
DOI 10.1155/2015/317859, PubMed 26221541
Bergan S, Bremer S, Vethe NT (2015)
Drug target molecules to guide immunosuppression
Clin Biochem, 49 (4-5), 411-8
DOI 10.1016/j.clinbiochem.2015.10.001, PubMed 26453533
Bernard JP, Khiabani HZ, Hilberg T, Karinen R, Slørdal L, Waal H, Mørland J (2015)
Characteristics of methadone-related fatalities in Norway
J Forensic Leg Med, 36, 114-20
DOI 10.1016/j.jflm.2015.09.011, PubMed 26439870
Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS (2015)
Progress report on new antiepileptic drugs: A summary of the Twelfth Eilat Conference (EILAT XII)
Epilepsy Res, 111, 85-141
DOI 10.1016/j.eplepsyres.2015.01.001, PubMed 25769377
Bjørner T, Anwar T, Brede WR, Hemmersbach P, Slørdal L (2015)
[A man with a changed appearance]
Tidsskr Nor Laegeforen, 135 (3), 243-5
DOI 10.4045/tidsskr.14.0886, PubMed 25668542
Bremer S, Fløisand Y, Brinch L, Gedde-Dahl T, Bergan S (2015)
Glutathione Transferase Gene Variants Influence Busulfan Pharmacokinetics and Outcome After Myeloablative Conditioning
Ther Drug Monit, 37 (4), 493-500
DOI 10.1097/FTD.0000000000000180, PubMed 25565670
Cehajic I, Bergan S, Bjordal K (2015)
Pharmacist assessment of drug-related problems on an oncology ward
Eur. J. Hosp. Pharm.-Sci. Pract., 22 (4), 194-197
de Graav GN, Bergan S, Baan CC, Weimar W, van Gelder T, Hesselink DA (2015)
Therapeutic Drug Monitoring of Belatacept in Kidney Transplantation
Ther Drug Monit, 37 (5), 560-7
DOI 10.1097/FTD.0000000000000179, PubMed 25551406
Fagermoen E, Sulheim D, Winger A, Andersen AM, Gjerstad J, Godang K, Rowe PC, Saul JP, Skovlund E, Wyller VB (2015)
Effects of low-dose clonidine on cardiovascular and autonomic variables in adolescents with chronic fatigue: a randomized controlled trial
BMC Pediatr, 15, 117
DOI 10.1186/s12887-015-0428-2, PubMed 26357864
Feng YZ, Nikolić N, Bakke SS, Kase ET, Guderud K, Hjelmesæth J, Aas V, Rustan AC, Thoresen GH (2015)
Myotubes from lean and severely obese subjects with and without type 2 diabetes respond differently to an in vitro model of exercise
Am J Physiol Cell Physiol, 308 (7), C548-56
DOI 10.1152/ajpcell.00314.2014, PubMed 25608533
Haase CB, Backer V, Kalsen A, Rzeppa S, Hemmersbach P, Hostrup M (2015)
The influence of exercise and dehydration on the urine concentrations of salbutamol after inhaled administration of 1600 µg salbutamol as a single dose in relation to doping analysis
Drug Test Anal, 8 (7), 613-20
DOI 10.1002/dta.1828, PubMed 26044066
Hjelmeland K, Gustavsen I, Bernard JP, Mørland J (2015)
Can a simple clinical test detect impairment of zopiclone and alcohol? - A randomized controlled trial
Forensic Sci Int, 248, 129-33
DOI 10.1016/j.forsciint.2014.12.028, PubMed 25617762
Hovda KE, Gadeholt G, Evtodienko V, Jacobsen D (2015)
A novel bedside diagnostic test for methanol poisoning using dry chemistry for formate
Scand J Clin Lab Invest, 75 (7), 610-4
DOI 10.3109/00365513.2015.1066847, PubMed 26203958
Hullstein IR, Malerod-Fjeld H, Dehnes Y, Hemmersbach P (2015)
Black market products confiscated in Norway 2011-2014 compared to analytical findings in urine samples
Drug Test Anal, 7 (11-12), 1025-9
DOI 10.1002/dta.1900, PubMed 26607218
Impellizzeri AA, Pappalardo M, Basile L, Manfra O, Andressen KW, Krobert KA, Messina A, Levy FO, Guccione S (2015)
Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis
Front Behav Neurosci, 9, 92
DOI 10.3389/fnbeh.2015.00092, PubMed 26005408
Jabeen S, Holmboe L, Alnæs GI, Andersen AM, Hall KS, Kristensen VN (2015)
Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate
Pharmacogenomics J, 15 (5), 385-90
DOI 10.1038/tpj.2015.11, PubMed 25778468
Johannessen Landmark C, Beiske G, Baftiu A, Burns ML, Johannessen SI (2015)
Experience from therapeutic drug monitoring and gender aspects of gabapentin and pregabalin in clinical practice
Seizure, 28, 88-91
DOI 10.1016/j.seizure.2015.02.017, PubMed 25758302
Johannessen Landmark C, I Johannessen S (2015)
Pharmacotherapy in epilepsy - does gender affect safety?
Expert Opin Drug Saf, 15 (1), 1-4
DOI 10.1517/14740338.2016.1117606, PubMed 26650146
Karlsen Bjånes T, Mjåset Hjertø E, Lønne L, Aronsen L, Andsnes Berg J, Bergan S, Otto Berg-Hansen G, Bernard JP, Larsen Burns M, Toralf Fosen J, Frost J, Hilberg T, Krabseth HM, Kvan E, Narum S, Austgulen Westin A (2015)
Pharmacology Portal: An Open Database for Clinical Pharmacologic Laboratory Services
Clin Ther, 38 (1), 222-6
DOI 10.1016/j.clinthera.2015.10.015, PubMed 26546404
Kase ET, Feng YZ, Badin PM, Bakke SS, Laurens C, Coue M, Langin D, Gaster M, Thoresen GH, Rustan AC, Moro C (2015)
Primary defects in lipolysis and insulin action in skeletal muscle cells from type 2 diabetic individuals
Biochim Biophys Acta, 1851 (9), 1194-201
DOI 10.1016/j.bbalip.2015.03.005, PubMed 25819461
Kaupang Å, Paulsen SM, Steindal CC, Ravna AW, Sylte I, Halvorsen TG, Thoresen GH, Hansen TV (2015)
Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618
Eur J Med Chem, 94, 229-36
DOI 10.1016/j.ejmech.2015.03.006, PubMed 25768705
Kloster-Jensen K, Vethe NT, Bremer S, Abadpour S, Korsgren O, Foss A, Bergan S, Scholz H (2015)
Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro
Transpl Int, 28 (10), 1152-61
DOI 10.1111/tri.12617, PubMed 26046470
Kong XY, Kase ET, Herskedal A, Schjalm C, Damme M, Nesset CK, Thoresen GH, Rustan AC, Eskild W (2015)
Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver
PLoS One, 10 (6), e0129402
DOI 10.1371/journal.pone.0129402, PubMed 26047317
Kringen MK (2015)
Analysis of Copy Number Variation by Pyrosequencing® Using Paralogous Sequences
Methods Mol Biol, 1315, 115-21
DOI 10.1007/978-1-4939-2715-9_9, PubMed 26103895
Kringen MK, Stormo C, Berg JP, Terry SF, Vocke CM, Rizvi S, Hendig D, Piehler AP (2015)
Copy number variation in the ATP-binding cassette transporter ABCC6 gene and ABCC6 pseudogenes in patients with pseudoxanthoma elasticum
Mol Genet Genomic Med, 3 (3), 233-7
DOI 10.1002/mgg3.137, PubMed 26029710
Manfra O, Van Craenenbroeck K, Skieterska K, Frimurer T, Schwartz TW, Levy FO, Andressen KW (2015)
Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1
ACS Chem Neurosci, 6 (7), 1206-18
DOI 10.1021/cn500339p, PubMed 25706089
Nordal K, Øiestad EL, Enger A, Christophersen AS, Vindenes V (2015)
Detection Times of Diazepam, Clonazepam, and Alprazolam in Oral Fluid Collected From Patients Admitted to Detoxification, After High and Repeated Drug Intake
Ther Drug Monit, 37 (4), 451-60
DOI 10.1097/FTD.0000000000000174, PubMed 25549207
Olberg DE, Hausner SH, Bauer N, Klaveness J, Indrevoll B, Andressen KW, Dahl M, Levy FO, Sutcliffe JL, Haraldsen I (2015)
Radiosynthesis of high affinity fluorine-18 labeled GnRH peptide analogues: in vitro studies and in vivo assessment of brain uptake in rats
MedChemComm, 6 (4), 708-714
Opdal MS, Arnesen M, Müller LD, Hullstein I, Sayed K, Brørs O, Kringen M, Sagedal S, Gjesdal K, Krajci P (2015)
Effects of Hemodialysis on Methadone Pharmacokinetics and QTc
Clin Ther, 37 (7), 1594-9
DOI 10.1016/j.clinthera.2015.04.009, PubMed 25963997
Ørstavik Ø, Manfra O, Andressen KW, Andersen GØ, Skomedal T, Osnes JB, Levy FO, Krobert KA (2015)
The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium
PLoS One, 10 (3), e0115547
DOI 10.1371/journal.pone.0115547, PubMed 25738589
Reiter L, Westergren T (2015)
Emergency contraception in overweight - to trust?
Tidsskr. Nor. Laegeforen., 135 (18), 1629-1630
Robertsen I, Åsberg A, Ingerø AO, Vethe NT, Bremer S, Bergan S, Midtvedt K (2015)
Use of generic tacrolimus in elderly renal transplant recipients: precaution is needed
Transplantation, 99 (3), 528-32
DOI 10.1097/TP.0000000000000384, PubMed 25148382
Robertsen I, Vethe NT, Midtvedt K, Falck P, Christensen H, Åsberg A (2015)
Closer to the Site of Action: Everolimus Concentrations in Peripheral Blood Mononuclear Cells Correlate Well With Whole Blood Concentrations
Ther Drug Monit, 37 (5), 675-80
DOI 10.1097/FTD.0000000000000185, PubMed 25565673
Rogeberg M, Almdahl IS, Wettergreen M, Nilsson LN, Fladby T (2015)
Isobaric Quantification of Cerebrospinal Fluid Amyloid-β Peptides in Alzheimer's Disease: C-Terminal Truncation Relates to Early Measures of Neurodegeneration
J Proteome Res, 14 (11), 4834-43
DOI 10.1021/acs.jproteome.5b00668, PubMed 26452689
Rogeberg M, Wettergreen M, Nilsson LN, Fladby T (2015)
Identification of amyloid beta mid-domain fragments in human cerebrospinal fluid
Biochimie, 113, 86-92
DOI 10.1016/j.biochi.2015.03.022, PubMed 25866191
Rzeppa S, Heinrich G, Hemmersbach P (2015)
Analysis of anabolic androgenic steroids as sulfate conjugates using high performance liquid chromatography coupled to tandem mass spectrometry
Drug Test Anal, 7 (11-12), 1030-9
DOI 10.1002/dta.1895, PubMed 26472592
Salvador CL, Tøndel C, Mørkrid L, Bjerre A, Brun A, Bolann B, Brackman D, Bergan S (2015)
Glomerular filtration rate measured by iohexol clearance: A comparison of venous samples and capillary blood spots
Scand J Clin Lab Invest, 75 (8), 710-6
DOI 10.3109/00365513.2015.1091091, PubMed 26426851
Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KE (2015)
Small bowel, celiac disease and adaptive immunity
Dig Dis, 33 (2), 115-21
DOI 10.1159/000369512, PubMed 25925911
Størset E, Åsberg A, Skauby M, Neely M, Bergan S, Bremer S, Midtvedt K (2015)
Improved Tacrolimus Target Concentration Achievement Using Computerized Dosing in Renal Transplant Recipients--A Prospective, Randomized Study
Transplantation, 99 (10), 2158-66
DOI 10.1097/TP.0000000000000708, PubMed 25886918
Tveteraas IH, Aasrum M, Brusevold IJ, Ødegård J, Christoffersen T, Sandnes D (2015)
Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells
Tumour Biol, 37 (2), 2519-26
DOI 10.1007/s13277-015-4010-1, PubMed 26386720

Publications 2014

Brudeli B, Navaratnarajah M, Andressen KW, Manfra O, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2014)
Discovery and pharmacological profile of new hydrophilic 5-HT(4) receptor antagonists
Bioorg Med Chem Lett, 24 (18), 4598-4602
DOI 10.1016/j.bmcl.2014.06.083, PubMed 25149506
Brusevold IJ, Tveteraas IH, Aasrum M, Ødegård J, Sandnes DL, Christoffersen T (2014)
Role of LPAR3, PKC and EGFR in LPA-induced cell migration in oral squamous carcinoma cells
BMC Cancer, 14, 432
DOI 10.1186/1471-2407-14-432, PubMed 24928086
Dehnes Y, Myrvold L, Ström H, Ericsson M, Hemmersbach P (2014)
MAIIA EPO SeLect-a rapid screening kit for the detection of recombinant EPO analogues in doping control: inter-laboratory prevalidation and normative study of athlete urine and plasma samples
Drug Test Anal, 6 (11-12), 1144-50
DOI 10.1002/dta.1752, PubMed 25421537
Haug JB, Berild D, Walberg M, Reikvam Å (2014)
Hospital- and patient-related factors associated with differences in hospital antibiotic use: analysis of national surveillance results
Antimicrob Resist Infect Control, 3 (1), 40
DOI 10.1186/s13756-014-0040-5, PubMed 25598971
Høgmoen Åstrand OA, Gikling I, Sylte I, Rustan AC, Thoresen GH, Rongved P, Kase ET (2014)
Development of new LXR modulators that regulate LXR target genes and reduce lipogenesis in human cell models
Eur J Med Chem, 74, 258-63
DOI 10.1016/j.ejmech.2014.01.003, PubMed 24480357
Høiseth G, Fjeld B, Burns ML, Strand DH, Vindenes V (2014)
Long-term stability of morphine, codeine, and 6-acetylmorphine in real-life whole blood samples, stored at -20°C
Forensic Sci Int, 239, 6-10
DOI 10.1016/j.forsciint.2014.03.008, PubMed 24709028
Holst L, Havnen GC, Nordeng H (2014)
Echinacea and elderberry-should they be used against upper respiratory tract infections during pregnancy?
Front Pharmacol, 5, 31
DOI 10.3389/fphar.2014.00031, PubMed 24624087
Hostrup M, Kalsen A, Bangsbo J, Hemmersbach P, Karlsson S, Backer V (2014)
High-dose inhaled terbutaline increases muscle strength and enhances maximal sprint performance in trained men
Eur J Appl Physiol, 114 (12), 2499-508
DOI 10.1007/s00421-014-2970-2, PubMed 25113095
Hostrup M, Kalsen A, Ortenblad N, Juel C, Mørch K, Rzeppa S, Karlsson S, Backer V, Bangsbo J (2014)
β2-adrenergic stimulation enhances Ca2+ release and contractile properties of skeletal muscles, and counteracts exercise-induced reductions in Na+-K+-ATPase Vmax in trained men
J Physiol, 592 (24), 5445-59
DOI 10.1113/jphysiol.2014.277095, PubMed 25344552
Hullstein I, Sagredo C, Hemmersbach P (2014)
Carbon isotope ratios of nandrolone, boldenone, and testosterone preparations seized in Norway compared to those of endogenously produced steroids in a Nordic reference population
Drug Test Anal, 6 (11-12), 1163-9
DOI 10.1002/dta.1745, PubMed 25388436
Husøy MA, Brinch L, Tjønnfjord GE, Gedde-Dahl T, Heldal D, Holme PA, Dybedal I, Kolstad A, Akkök ÇA, Rollag H, Gaustad P, Bergan S, Egeland T, Josefsen D, Kvalheim G, Fløisand Y (2014)
[Allogeneic stem-cell transplantation in adults 1985-2012: results and development]
Tidsskr Nor Laegeforen, 134 (16), 1569-75
DOI 10.4045/tidsskr.13.1415, PubMed 25178233
Jendresen CB, Cui H, Zhang X, Vlodavsky I, Nilsson LNG, Li JP (2014)
Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice
J Biol Chem, 290 (8), 5053-5064
DOI 10.1074/jbc.M114.600569, PubMed 25548284
Kalsen A, Hostrup M, Karlsson S, Hemmersbach P, Bangsbo J, Backer V (2014)
Effect of inhaled terbutaline on substrate utilization and 300-kcal time trial performance
J Appl Physiol (1985), 117 (10), 1180-7
DOI 10.1152/japplphysiol.00635.2014, PubMed 25257871
Kilander MB, Petersen J, Andressen KW, Ganji RS, Levy FO, Schuster J, Dahl N, Bryja V, Schulte G (2014)
Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6
FASEB J, 28 (5), 2293-305
DOI 10.1096/fj.13-246363, PubMed 24500924
Kringen MK, Piehler AP, Grimholt RM, Opdal MS, Haug KB, Urdal P (2014)
Serum bilirubin concentration in healthy adult North-Europeans is strictly controlled by the UGT1A1 TA-repeat variants
PLoS One, 9 (2), e90248
DOI 10.1371/journal.pone.0090248, PubMed 24587300
Levinsen M, Rotevatn EØ, Rosthøj S, Nersting J, Abrahamsson J, Appell ML, Bergan S, Bechensteen AG, Harila-Saari A, Heyman M, Jonsson OG, Maxild JB, Niemi M, Söderhäll S, Schmiegelow K, Nordic Society of Paediatric Haematology, Oncology (2014)
Pharmacogenetically based dosing of thiopurines in childhood acute lymphoblastic leukemia: influence on cure rates and risk of second cancer
Pediatr Blood Cancer, 61 (5), 797-802
DOI 10.1002/pbc.24921, PubMed 24395436
Liu F, Qimuge, Hao J, Yan H, Bach T, Fan L, Morigen (2014)
AspC-mediated aspartate metabolism coordinates the Escherichia coli cell cycle
PLoS One, 9 (3), e92229
DOI 10.1371/journal.pone.0092229, PubMed 24670900
Lunde I, Bremer S, Midtvedt K, Mohebi B, Dahl M, Bergan S, Åsberg A, Christensen H (2014)
The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients
Eur J Clin Pharmacol, 70 (6), 685-93
DOI 10.1007/s00228-014-1656-3, PubMed 24658827
Melsom CB, Hussain RI, Ørstavik Ø, Aronsen JM, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Krobert KA (2014)
Non-classical regulation of β1- and β 2-adrenoceptor-mediated inotropic responses in rat heart ventricle by the G protein Gi
Naunyn Schmiedebergs Arch Pharmacol, 387 (12), 1177-86
DOI 10.1007/s00210-014-1036-7, PubMed 25216690
Melsom CB, Ørstavik Ø, Osnes JB, Skomedal T, Levy FO, Krobert KA (2014)
Gi proteins regulate adenylyl cyclase activity independent of receptor activation
PLoS One, 9 (9), e106608
DOI 10.1371/journal.pone.0106608, PubMed 25203113
Moltzau LR, Aronsen JM, Meier S, Skogestad J, Ørstavik Ø, Lothe GB, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
Different compartmentation of responses to brain natriuretic peptide and C-type natriuretic peptide in failing rat ventricle
J Pharmacol Exp Ther, 350 (3), 681-90
DOI 10.1124/jpet.114.214882, PubMed 25022512
Moltzau LR, Meier S, Aronsen JM, Afzal F, Sjaastad I, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2014)
Differential regulation of C-type natriuretic peptide-induced cGMP and functional responses by PDE2 and PDE3 in failing myocardium
Naunyn Schmiedebergs Arch Pharmacol, 387 (5), 407-17
DOI 10.1007/s00210-013-0953-1, PubMed 24424715
Narum S, Westergren T, Klemp M (2014)
Corticosteroids and risk of gastrointestinal bleeding: a systematic review and meta-analysis
BMJ Open, 4 (5), e004587
DOI 10.1136/bmjopen-2013-004587, PubMed 24833682
Nuruddin S, Syverstad GH, Lillehaug S, Leergaard TB, Nilsson LN, Ropstad E, Krogenæs A, Haraldsen IR, Torp R (2014)
Elevated mRNA-levels of gonadotropin-releasing hormone and its receptor in plaque-bearing Alzheimer's disease transgenic mice
PLoS One, 9 (8), e103607
DOI 10.1371/journal.pone.0103607, PubMed 25089901
Orstavik O, Ata SH, Riise J, Dahl CP, Andersen GØ, Levy FO, Skomedal T, Osnes JB, Qvigstad E (2014)
Inhibition of phosphodiesterase-3 by levosimendan is sufficient to account for its inotropic effect in failing human heart
Br J Pharmacol, 171 (23), 5169-81
DOI 10.1111/bph.12647, PubMed 24547784
Rahman MA, Kristiansen PE, Veiseth SV, Andersen JT, Yap KL, Zhou MM, Sandlie I, Thorstensen T, Aalen RB (2014)
The arabidopsis histone methyltransferase SUVR4 binds ubiquitin via a domain with a four-helix bundle structure
Biochemistry, 53 (13), 2091-100
DOI 10.1021/bi401436h, PubMed 24625295
Robertsen I, Asberg A, Granseth T, Vethe NT, Akhlaghi F, Ghareeb M, Molden E, Reier-Nilsen M, Holdaas H, Midtvedt K (2014)
More potent lipid-lowering effect by rosuvastatin compared with fluvastatin in everolimus-treated renal transplant recipients
Transplantation, 97 (12), 1266-71
DOI 10.1097/01.TP.0000443225.66960.7e, PubMed 24521776
Sæves I, Line PD, Bremer S, Vethe NT, Tveit RG, Meltevik TJ, Bergan S (2014)
Tacrolimus exposure and mycophenolate pharmacokinetics and pharmacodynamics early after liver transplantation
Ther Drug Monit, 36 (1), 46-53
DOI 10.1097/FTD.0b013e31829dcb66, PubMed 24081206
Smith R, Solberg R, Jacobsen LL, Voreland AL, Rustan AC, Thoresen GH, Johansen HT (2014)
Simvastatin inhibits glucose metabolism and legumain activity in human myotubes
PLoS One, 9 (1), e85721
DOI 10.1371/journal.pone.0085721, PubMed 24416446
Stormo C, Kringen MK, Lyle R, Olstad OK, Sachse D, Berg JP, Piehler AP (2014)
RNA-sequencing analysis of HepG2 cells treated with atorvastatin
PLoS One, 9 (8), e105836
DOI 10.1371/journal.pone.0105836, PubMed 25153832
Størset E, Holford N, Hennig S, Bergmann TK, Bergan S, Bremer S, Åsberg A, Midtvedt K, Staatz CE (2014)
Improved prediction of tacrolimus concentrations early after kidney transplantation using theory-based pharmacokinetic modelling
Br J Clin Pharmacol, 78 (3), 509-23
DOI 10.1111/bcp.12361, PubMed 25279405
Sulheim D, Fagermoen E, Winger A, Andersen AM, Godang K, Müller F, Rowe PC, Saul JP, Skovlund E, Øie MG, Wyller VB (2014)
Disease mechanisms and clonidine treatment in adolescent chronic fatigue syndrome: a combined cross-sectional and randomized clinical trial
JAMA Pediatr, 168 (4), 351-60
DOI 10.1001/jamapediatrics.2013.4647, PubMed 24493300
Vethe NT, Ali AM, Reine PA, Andersen AM, Bremer S, Line PD, Rootwelt H, Bergan S (2014)
Simultaneous quantification of IMPDH activity and purine bases in lymphocytes using LC-MS/MS: assessment of biomarker responses to mycophenolic acid
Ther Drug Monit, 36 (1), 108-18
DOI 10.1097/FTD.0b013e3182a13900, PubMed 24061448
Westergren T, Hjelmeland K, Kristoffersen B, Johannessen SI, Kalikstad B (2014)
Probable topiramate-induced diarrhea in a 2-month-old breast-fed child - A case report
Epilepsy Behav Case Rep, 2, 22-3
DOI 10.1016/j.ebcr.2013.12.006, PubMed 25667861
Ytrehus K, Larsen T, Christensen G, Stensløkken KO, Levy FO (2014)
In memory of Guro Valen (1960-2014)
J Mol Cell Cardiol, 79, 254-5
DOI 10.1016/j.yjmcc.2014.11.026, PubMed 25490150

Publications 2013

Aasrum M, Ødegård J, Sandnes D, Christoffersen T (2013)
The involvement of the docking protein Gab1 in mitogenic signalling induced by EGF and HGF in rat hepatocytes
Biochim Biophys Acta, 1833 (12), 3286-3294
DOI 10.1016/j.bbamcr.2013.10.004, PubMed 24126105
Åsberg A, Midtvedt K, van Guilder M, Størset E, Bremer S, Bergan S, Jelliffe R, Hartmann A, Neely MN (2013)
Inclusion of CYP3A5 genotyping in a nonparametric population model improves dosing of tacrolimus early after transplantation
Transpl Int, 26 (12), 1198-207
DOI 10.1111/tri.12194, PubMed 24118301
Bach T, Bergholtz S, Riise J, Qvigstad E, Skomedal T, Osnes JB, Levy FO (2013)
Identification of small molecule NPR-B antagonists by high throughput screening--potential use in heart failure
Naunyn Schmiedebergs Arch Pharmacol, 387 (1), 5-14
DOI 10.1007/s00210-013-0940-6, PubMed 24297249
Brudeli B, Andressen KW, Moltzau LR, Nilsen NO, Levy FO, Klaveness J (2013)
Acidic biphenyl derivatives: synthesis and biological activity of a new series of potent 5-HT(4) receptor antagonists
Bioorg Med Chem, 21 (22), 7134-45
DOI 10.1016/j.bmc.2013.09.004, PubMed 24113240
Brudeli B, Moltzau LR, Nguyen CH, Andressen KW, Nilsen NO, Levy FO, Klaveness J (2013)
Synthesis and pharmacological properties of a new hydrophilic and orally bioavailable 5-HT4 antagonist
Eur J Med Chem, 64, 629-37
DOI 10.1016/j.ejmech.2013.03.060, PubMed 23711770
Dehnes Y, Shalina A, Myrvold L (2013)
Detection of recombinant EPO in blood and urine samples with EPO WGA MAIIA, IEF and SAR-PAGE after microdose injections
Drug Test Anal, 5 (11-12), 861-9
DOI 10.1002/dta.1579, PubMed 24190107
Eibye K, Elers J, Pedersen L, Henninge J, Hemmersbach P, Dalhoff K, Backer V (2013)
Formoterol concentrations in blood and urine: the World Anti-Doping Agency 2012 regulations
Med Sci Sports Exerc, 45 (1), 16-22
DOI 10.1249/MSS.0b013e318269fba2, PubMed 22843108
Gellynck E, Heyninck K, Andressen KW, Haegeman G, Levy FO, Vanhoenacker P, Van Craenenbroeck K (2013)
The serotonin 5-HT7 receptors: two decades of research
Exp Brain Res, 230 (4), 555-68
DOI 10.1007/s00221-013-3694-y, PubMed 24042216
Gravning J, Ahmed MS, Qvigstad E, Krobert K, Edvardsen T, Moe IT, Hagelin EM, Sagave J, Valen G, Levy FO, Osnes JB, Skomedal T, Attramadal H (2013)
Connective tissue growth factor/CCN2 attenuates β-adrenergic receptor responsiveness and cardiotoxicity by induction of G protein-coupled receptor kinase-5 in cardiomyocytes
Mol Pharmacol, 84 (3), 372-83
DOI 10.1124/mol.113.087312, PubMed 23778361
Gu GJ, Wu D, Lund H, Sunnemark D, Kvist AJ, Milner R, Eckersley S, Nilsson LN, Agerman K, Landegren U, Kamali-Moghaddam M (2013)
Elevated MARK2-dependent phosphorylation of Tau in Alzheimer's disease
J Alzheimers Dis, 33 (3), 699-713
DOI 10.3233/JAD-2012-121357, PubMed 23001711
Gumucio A, Lannfelt L, Nilsson LN (2013)
Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging
BMC Neurosci, 14, 148
DOI 10.1186/1471-2202-14-148, PubMed 24261309
Henning O, Baftiu A, Johannessen SI, Landmark CJ (2013)
Withdrawal of antiepileptic drugs during presurgical video-EEG monitoring: an observational study for evaluation of current practice at a referral center for epilepsy
Acta Neurol Scand, 129 (4), 243-51
DOI 10.1111/ane.12179, PubMed 23980664
Hostrup M, Kalsen A, Auchenberg M, Rzeppa S, Hemmersbach P, Bangsbo J, Backer V (2013)
Urine concentrations of oral salbutamol in samples collected after intense exercise in endurance athletes
Drug Test Anal, 6 (6), 528-32
DOI 10.1002/dta.1568, PubMed 24166762
Kalimo H, Lalowski M, Bogdanovic N, Philipson O, Bird TD, Nochlin D, Schellenberg GD, Brundin R, Olofsson T, Soliymani R, Baumann M, Wirths O, Bayer TA, Nilsson LN, Basun H, Lannfelt L, Ingelsson M (2013)
The Arctic AβPP mutation leads to Alzheimer's disease pathology with highly variable topographic deposition of differentially truncated Aβ
Acta Neuropathol Commun, 1, 60
DOI 10.1186/2051-5960-1-60, PubMed 24252272
Karouni M, Henning O, Larsson PG, Johannessen SI, Johannessen Landmark C (2013)
Pharmacological treatment of psychiatric comorbidity in patients with refractory epilepsy
Epilepsy Behav, 29 (1), 77-81
DOI 10.1016/j.yebeh.2013.06.031, PubMed 23939032
Kvehaugen AS, Melien Ø, Holmen OL, Laivuori H, Dechend R, Staff AC (2013)
PP084. Hypertension after preeclampsia in women with C1114G polymorphism in rgs2 (the regulator of g protein signaling 2)
Pregnancy Hypertens, 3 (2), 98
DOI 10.1016/j.preghy.2013.04.109, PubMed 26105937
Lærum H, Bremer S, Bergan S, Grünfeld T (2013)
A taste of individualized medicine: physicians' reactions to automated genetic interpretations
J Am Med Inform Assoc, 21 (e1), e143-6
DOI 10.1136/amiajnl-2012-001587, PubMed 24001515
Lau C, Gunnarsen KS, Høydahl LS, Andersen JT, Berntzen G, Pharo A, Lindstad JK, Ludviksen JK, Brekke OL, Barratt-Due A, Nielsen EW, Stokes CR, Espevik T, Sandlie I, Mollnes TE (2013)
Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation
J Immunol, 191 (9), 4769-77
DOI 10.4049/jimmunol.1301653, PubMed 24062486
Levy FO (2013)
Cardiac PDEs and crosstalk between cAMP and cGMP signalling pathways in the regulation of contractility
Naunyn Schmiedebergs Arch Pharmacol, 386 (8), 665-70
DOI 10.1007/s00210-013-0874-z, PubMed 23649864
Lillehaug S, Syverstad GH, Nilsson LN, Bjaalie JG, Leergaard TB, Torp R (2013)
Brainwide distribution and variance of amyloid-beta deposits in tg-ArcSwe mice
Neurobiol Aging, 35 (3), 556-64
DOI 10.1016/j.neurobiolaging.2013.09.013, PubMed 24126157
Lillenes MS, Støen M, Gómez-Muñoz M, Torp R, Günther CC, Nilsson LN, Tønjum T (2013)
Transient OGG1, APE1, PARP1 and Polβ expression in an Alzheimer's disease mouse model
Mech Ageing Dev, 134 (10), 467-77
DOI 10.1016/j.mad.2013.09.002, PubMed 24121118
Lund H, Snilsberg AH, Halvorsen TG, Hemmersbach P, Reubsaet L (2013)
Comparison of newly developed immuno-MS method with existing DELFIA(®) immunoassay for human chorionic gonadotropin determination in doping analysis
Bioanalysis, 5 (5), 623-30
DOI 10.4155/bio.13.8, PubMed 23425277
Magnusson K, Sehlin D, Syvänen S, Svedberg MM, Philipson O, Söderberg L, Tegerstedt K, Holmquist M, Gellerfors P, Tolmachev V, Antoni G, Lannfelt L, Hall H, Nilsson LN (2013)
Specific uptake of an amyloid-β protofibril-binding antibody-tracer in AβPP transgenic mouse brain
J Alzheimers Dis, 37 (1), 29-40
DOI 10.3233/JAD-130029, PubMed 23780660
Mathiesen L, Nielsen LK, Andersen JT, Grevys A, Sandlie I, Michaelsen TE, Hedegaard M, Knudsen LE, Dziegiel MH (2013)
Maternofetal transplacental transport of recombinant IgG antibodies lacking effector functions
Blood, 122 (7), 1174-81
DOI 10.1182/blood-2012-12-473843, PubMed 23843496
Molenaar P, Christ T, Hussain RI, Engel A, Berk E, Gillette KT, Chen L, Galindo-Tovar A, Krobert KA, Ravens U, Levy FO, Kaumann AJ (2013)
PDE3, but not PDE4, reduces β₁ - and β₂-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients
Br J Pharmacol, 169 (3), 528-38
DOI 10.1111/bph.12167, PubMed 23489141
Moltzau LR, Aronsen JM, Meier S, Nguyen CH, Hougen K, Ørstavik Ø, Sjaastad I, Christensen G, Skomedal T, Osnes JB, Levy FO, Qvigstad E (2013)
SERCA2 activity is involved in the CNP-mediated functional responses in failing rat myocardium
Br J Pharmacol, 170 (2), 366-79
DOI 10.1111/bph.12282, PubMed 23808942
Narum S, Solhaug V, Myhr K, Brørs O, Kringen MK (2013)
Characterisation of non-warfarin-associated bleeding events reported to the Norwegian spontaneous reporting system
Eur J Clin Pharmacol, 69 (7), 1445-52
DOI 10.1007/s00228-013-1479-7, PubMed 23423243
Reine PA, Vethe NT, Kongsgaard UE, Andersen AM, Line PD, Ali AM, Bergan S (2013)
Mycophenolate pharmacokinetics and inosine monophosphate dehydrogenase activity in liver transplant recipients with an emphasis on therapeutic drug monitoring
Scand J Clin Lab Invest, 73 (2), 117-24
DOI 10.3109/00365513.2012.745947, PubMed 23281843
Rogeberg M, Malerod H, Roberg-Larsen H, Aass C, Wilson SR (2013)
On-line solid phase extraction-liquid chromatography, with emphasis on modern bioanalysis and miniaturized systems
J Pharm Biomed Anal, 87, 120-9
DOI 10.1016/j.jpba.2013.05.006, PubMed 23746991
Skarstein S, Rosvold EO, Helseth S, Kvarme LG, Holager T, Småstuen MC, Lagerløv P (2013)
High-frequency use of over-the-counter analgesics among adolescents: reflections of an emerging difficult life, a cross-sectional study
Scand J Caring Sci, 28 (1), 49-56
DOI 10.1111/scs.12039, PubMed 23517110
Sørensen O, Andersen AM, Kristian A, Giercksky KE, Flatmark K (2013)
Impact of hyperthermia on pharmacokinetics of intraperitoneal mitomycin C in rats investigated by microdialysis
J Surg Oncol, 109 (6), 521-6
DOI 10.1002/jso.23527, PubMed 24347444
Stormo C, Bogsrud MP, Hermann M, Åsberg A, Piehler AP, Retterstøl K, Kringen MK (2013)
UGT1A1*28 is associated with decreased systemic exposure of atorvastatin lactone
Mol Diagn Ther, 17 (4), 233-7
DOI 10.1007/s40291-013-0031-x, PubMed 23580084
Størset E, Holford N, Midtvedt K, Bremer S, Bergan S, Åsberg A (2013)
Importance of hematocrit for a tacrolimus target concentration strategy
Eur J Clin Pharmacol, 70 (1), 65-77
DOI 10.1007/s00228-013-1584-7, PubMed 24071959
Strand OA, Sandberg M, Sylte I, Görbitz CH, Thoresen GH, Kase ET, Rongved P (2013)
Synthesis and initial biological evaluation of new mimics of the LXR-modulator 22(S)-hydroxycholesterol
Bioorg Med Chem, 22 (1), 643-50
DOI 10.1016/j.bmc.2013.10.024, PubMed 24268541

Publications 2012

Askim M, Haug A, Gadeholt G (2012)
Dietary intake of menaquinone-4 may determine hepatic and pancreatic menaquinone-4 in chickens
Food Nutr Res, 56
DOI 10.3402/fnr.v56i0.5380, PubMed 22481898
Bernard JP, Havnes I, Slørdal L, Waal H, Mørland J, Khiabani HZ (2012)
Methadone-related deaths in Norway
Forensic Sci Int, 224 (1-3), 111-6
DOI 10.1016/j.forsciint.2012.11.010, PubMed 23246070
Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS (2012)
Progress report on new antiepileptic drugs: a summary of the Eleventh Eilat Conference (EILAT XI)
Epilepsy Res, 103 (1), 2-30
DOI 10.1016/j.eplepsyres.2012.10.001, PubMed 23219031
Brattelid T, Qvigstad E, Moltzau LR, Bekkevold SV, Sandnes DL, Birkeland JA, Skomedal T, Osnes JB, Sjaastad I, Levy FO (2012)
The cardiac ventricular 5-HT4 receptor is functional in late foetal development and is reactivated in heart failure
PLoS One, 7 (9), e45489
DOI 10.1371/journal.pone.0045489, PubMed 23029047
Danese E, Montagnana M, Johnson JA, Rettie AE, Zambon CF, Lubitz SA, Suarez-Kurtz G, Cavallari LH, Zhao L, Huang M, Nakamura Y, Mushiroda T, Kringen MK, Borgiani P, Ciccacci C, Au NT, Langaee T, Siguret V, Loriot MA, Sagreiya H, Altman RB, Shahin MH, Scott SA, Khalifa SI, Chowbay B et al. (2012)
Impact of the CYP4F2 p.V433M polymorphism on coumarin dose requirement: systematic review and meta-analysis
Clin Pharmacol Ther, 92 (6), 746-56
DOI 10.1038/clpt.2012.184, PubMed 23132553
Elers J, Hostrup M, Pedersen L, Henninge J, Hemmersbach P, Dalhoff K, Backer V (2012)
Urine and serum concentrations of inhaled and oral terbutaline
Int J Sports Med, 33 (12), 1026-33
DOI 10.1055/s-0032-1311590, PubMed 22782385
Elers J, Pedersen L, Henninge J, Hemmersbach P, Dalhoff K, Backer V (2012)
The pharmacokinetic profile of inhaled and oral salbutamol in elite athletes with asthma and nonasthmatic subjects
Clin J Sport Med, 22 (2), 140-5
DOI 10.1097/JSM.0b013e31823513e1, PubMed 22388343
Fjeld B, Burns ML, Karinen R, Larssen B, Smith-Kielland A, Vindenes V (2012)
Long-term stability of GHB in post-mortem samples and samples from living persons, stored at -20°C, using fluoride preservatives
Forensic Sci Int, 222 (1-3), 47-51
DOI 10.1016/j.forsciint.2012.04.033, PubMed 22648054
Fretheim A, Odgaard-Jensen J, Brørs O, Madsen S, Njølstad I, Norheim OF, Svilaas A, Kristiansen IS, Thürmer H, Flottorp S (2012)
Comparative effectiveness of antihypertensive medication for primary prevention of cardiovascular disease: systematic review and multiple treatments meta-analysis
BMC Med, 10, 33
DOI 10.1186/1741-7015-10-33, PubMed 22480336
Gellynck E, Andressen KW, Lintermans B, Haegeman G, Levy FO, Vanhoenacker P, Van Craenenbroeck K (2012)
Biochemical and pharmacological study of N-linked glycosylation of the human serotonin 5-HT₇a receptor
FEBS J, 279 (11), 1994-2003
DOI 10.1111/j.1742-4658.2012.08581.x, PubMed 22448645
Gjersvik P, Helsing P, Holdaas H, Bergan S (2012)
[Immunosuppressive drugs and the development of skin cancer after organ transplantation]
Tidsskr Nor Laegeforen, 132 (18), 2064-8
DOI 10.4045/tidsskr.12.0389, PubMed 23038197
Gustavsen I, Hjelmeland K, Bernard JP, Mørland J (2012)
Individual psychomotor impairment in relation to zopiclone and ethanol concentrations in blood--a randomized controlled double-blinded trial
Addiction, 107 (5), 925-32
DOI 10.1111/j.1360-0443.2011.03693.x, PubMed 22008377
Hemmersbach P, Drange M, Rabin O, Botrè F, Dehnes Y (2012)
Doping analysis on solid ground
Tidsskr Nor Laegeforen, 132 (2), 130
DOI 10.4045/tidsskr.11.1330, PubMed 22278263
Holmboe L, Andersen AM, Mørkrid L, Slørdal L, Hall KS (2012)
High dose methotrexate chemotherapy: pharmacokinetics, folate and toxicity in osteosarcoma patients
Br J Clin Pharmacol, 73 (1), 106-14
DOI 10.1111/j.1365-2125.2011.04054.x, PubMed 21707700
Hussain RI, Aronsen JM, Afzal F, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2012)
The functional activity of inhibitory G protein (G(i)) is not increased in failing heart ventricle
J Mol Cell Cardiol, 56, 129-38
DOI 10.1016/j.yjmcc.2012.11.015, PubMed 23220156
Johannessen Landmark C, Baftiu A, Tysse I, Valsø B, Larsson PG, Rytter E, Johannessen SI (2012)
Pharmacokinetic variability of four newer antiepileptic drugs, lamotrigine, levetiracetam, oxcarbazepine, and topiramate: a comparison of the impact of age and comedication
Ther Drug Monit, 34 (4), 440-5
DOI 10.1097/FTD.0b013e31825ee389, PubMed 22777154
Jung ST, Kelton W, Kang TH, Ng DT, Andersen JT, Sandlie I, Sarkar CA, Georgiou G (2012)
Effective phagocytosis of low Her2 tumor cell lines with engineered, aglycosylated IgG displaying high FcγRIIa affinity and selectivity
ACS Chem Biol, 8 (2), 368-75
DOI 10.1021/cb300455f, PubMed 23030766
Kringen MK, Stormo C, Grimholt RM, Berg JP, Piehler AP (2012)
Copy number variations of the ATP-binding cassette transporter ABCC6 gene and its pseudogenes
BMC Res Notes, 5, 425
DOI 10.1186/1756-0500-5-425, PubMed 22873774
Lei P, Baysa A, Nebb HI, Valen G, Skomedal T, Osnes JB, Yang Z, Haugen F (2012)
Activation of Liver X receptors in the heart leads to accumulation of intracellular lipids and attenuation of ischemia-reperfusion injury
Basic Res Cardiol, 108 (1), 323
DOI 10.1007/s00395-012-0323-z, PubMed 23266787
Lund H, Snilsberg AH, Paus E, Halvorsen TG, Hemmersbach P, Reubsaet L (2012)
Sports drug testing using immuno-MS: clinical study comprising administration of human chorionic gonadotropin to males
Anal Bioanal Chem, 405 (5), 1569-76
DOI 10.1007/s00216-012-6566-6, PubMed 23203507
Nilsson LN, Gografe S, Costa DA, Hughes T, Dressler D, Potter H (2012)
USE OF FUSED CIRCULATIONS TO INVESTIGATE THE ROLE OF APOLIPOPROTEIN E AS AMYLOID CATALYST AND PERIPHERAL SINK IN ALZHEIMER'S DISEASE
Technol Innov, 14 (2), 199-208
DOI 10.3727/194982412X13462021398010, PubMed 23626867
Nordeng H, Havnen GC, Spigset O (2012)
Drug use and breastfeeding
Tidsskr Nor Laegeforen, 132 (9), 1089-93
DOI 10.4045/tidsskr.11.1104, PubMed 22614307
Opdal MS (2012)
[Sick from sickness, substance abuse or medicine]
Tidsskr Nor Laegeforen, 132 (1), 52
DOI 10.4045/tidsskr.11.0906, PubMed 22240832
Riise J, Ørstavik Ø, Qvigstad E, Dahl CP, Osnes JB, Skomedal T, Levy FO, Krobert KA (2012)
Prostaglandin E1 facilitates inotropic effects of 5-HT4 serotonin receptors and β-adrenoceptors in failing human heart
Basic Res Cardiol, 107 (5), 295
DOI 10.1007/s00395-012-0295-z, PubMed 22923058
Sæves I, Line PD, Bergan S (2012)
The pharmacokinetics of prednisolone and prednisone in adult liver transplant recipients early after transplantation
Ther Drug Monit, 34 (4), 452-9
DOI 10.1097/FTD.0b013e31825ee3f8, PubMed 22777155
Schjøtt J, Reppe LA, Roland PD, Westergren T (2012)
A question-answer pair (QAP) database integrated with websites to answer complex questions submitted to the Regional Medicines Information and Pharmacovigilance Centres in Norway (RELIS): a descriptive study
BMJ Open, 2 (2), e000642
DOI 10.1136/bmjopen-2011-000642, PubMed 22422916
Stormo C, Kringen MK, Grimholt RM, Berg JP, Piehler AP (2012)
A novel 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) splice variant with an alternative exon 1 potentially encoding an extended N-terminus
BMC Mol Biol, 13, 29
DOI 10.1186/1471-2199-13-29, PubMed 22989091
Yazaki PJ, Lee B, Channappa D, Cheung CW, Crow D, Chea J, Poku E, Li L, Andersen JT, Sandlie I, Orcutt KD, Wittrup KD, Shively JE, Raubitschek A, Colcher D (2012)
A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance
Protein Eng Des Sel, 26 (3), 187-93
DOI 10.1093/protein/gzs096, PubMed 23175797
Zhang X, Wang B, O'Callaghan P, Hjertström E, Jia J, Gong F, Zcharia E, Nilsson LN, Lannfelt L, Vlodavsky I, Lindahl U, Li JP (2012)
Heparanase overexpression impairs inflammatory response and macrophage-mediated clearance of amyloid-β in murine brain
Acta Neuropathol, 124 (4), 465-78
DOI 10.1007/s00401-012-0997-1, PubMed 22692572

Publications 2011

Afzal F, Qvigstad E, Aronsen JM, Moltzau LR, Sjaastad I, Skomedal T, Osnes JB, Levy FO (2011)
Agents increasing cyclic GMP amplify 5-HT4-elicited positive inotropic response in failing rat cardiac ventricle
Naunyn Schmiedebergs Arch Pharmacol, 384 (6), 543-53
DOI 10.1007/s00210-011-0670-6, PubMed 21901315
Ardal C, Iversen JH, Myhr K (2011)
New models for pharmaceutical innovation in low-income countries
Tidsskr Nor Laegeforen, 131 (20), 2016-8
DOI 10.4045/tidsskr.11.0658, PubMed 22016131
Baker K, Qiao SW, Kuo TT, Aveson VG, Platzer B, Andersen JT, Sandlie I, Chen Z, de Haar C, Lencer WI, Fiebiger E, Blumberg RS (2011)
Neonatal Fc receptor for IgG (FcRn) regulates cross-presentation of IgG immune complexes by CD8-CD11b+ dendritic cells
Proc Natl Acad Sci U S A, 108 (24), 9927-32
DOI 10.1073/pnas.1019037108, PubMed 21628593
Berrade L, Aisa B, Ramirez MJ, Galiano S, Guccione S, Moltzau LR, Levy FO, Nicoletti F, Battaglia G, Molinaro G, Aldana I, Monge A, Perez-Silanes S (2011)
Novel benzo[b]thiophene derivatives as new potential antidepressants with rapid onset of action
J Med Chem, 54 (8), 3086-90
DOI 10.1021/jm2000773, PubMed 21469694
Brattelid T, Levy FO (2011)
Quantification of GPCR mRNA using real-time RT-PCR
Methods Mol Biol, 746, 165-93
DOI 10.1007/978-1-61779-126-0_9, PubMed 21607857
Dehnes Y, Hemmersbach P (2011)
Effect of single doses of methoxypolyethylene glycol-epoetin beta (CERA, Mircera™) and epoetin delta (Dynepo™) on isoelectric erythropoietin profiles and haematological parameters
Drug Test Anal, 3 (5), 291-9
DOI 10.1002/dta.270, PubMed 21387570
Elers J, Pedersen L, Henninge J, Hemmersbach P, Dalhoff K, Backer V (2011)
Urine concentrations of repetitive doses of inhaled salbutamol
Int J Sports Med, 32 (8), 574-9
DOI 10.1055/s-0031-1273755, PubMed 21563035
Evang JA, Berg JP, Casar-Borota O, Lekva T, Kringen MK, Ramm-Pettersen J, Bollerslev J (2011)
Reduced levels of E-cadherin correlate with progression of corticotroph pituitary tumours
Clin Endocrinol (Oxf), 75 (6), 811-8
DOI 10.1111/j.1365-2265.2011.04109.x, PubMed 21595730
Gustavsen I, Hjelmeland K, Bernard JP, Mørland J (2011)
Psychomotor performance after intake of zopiclone compared with intake of ethanol: a randomized, controlled, double-blinded trial
J Clin Psychopharmacol, 31 (4), 481-8
DOI 10.1097/JCP.0b013e3182214be6, PubMed 21694628
Haug JB, Myhr R, Reikvam A (2011)
Pharmacy sales data versus ward stock accounting for the surveillance of broad-spectrum antibiotic use in hospitals
BMC Med Res Methodol, 11, 166
DOI 10.1186/1471-2288-11-166, PubMed 22166018
Hemmersbach P (2011)
The 29th Manfred Donike workshop on doping analysis
Drug Test Anal, 3 (11-12), 755
DOI 10.1002/dta.401, PubMed 22213683
Hovda KE, Julsrud J, Øvrebø S, Brørs O, Jacobsen D (2011)
Studies on ethylene glycol poisoning: one patient - 154 admissions
Clin Toxicol (Phila), 49 (6), 478-84
DOI 10.3109/15563650.2011.590140, PubMed 21824058
Hussain RI, Afzal F, Mørk HK, Aronsen JM, Sjaastad I, Osnes JB, Skomedal T, Levy FO, Krobert KA (2011)
Cyclic AMP-dependent inotropic effects are differentially regulated by muscarinic G(i)-dependent constitutive inhibition of adenylyl cyclase in failing rat ventricle
Br J Pharmacol, 162 (4), 908-16
DOI 10.1111/j.1476-5381.2010.01097.x, PubMed 21039419
Johannessen Landmark C, Johannessen SI, Tomson T (2011)
Host factors affecting antiepileptic drug delivery-pharmacokinetic variability
Adv Drug Deliv Rev, 64 (10), 896-910
DOI 10.1016/j.addr.2011.10.003, PubMed 22063021
Johansen JS, Westergren T, Lingaas E (2011)
[Post-exposure varicella prophylaxis]
Tidsskr Nor Laegeforen, 131 (17), 1645-8
DOI 10.4045/tidsskr.10.0149, PubMed 21901036
Landmark CJ, Fossmark H, Larsson PG, Rytter E, Johannessen SI (2011)
Prescription patterns of antiepileptic drugs in patients with epilepsy in a nation-wide population
Epilepsy Res, 95 (1-2), 51-9
DOI 10.1016/j.eplepsyres.2011.02.012, PubMed 21435840
Landmark CJ, Fossmark H, Larsson PG, Rytter E, Johannessen SI (2011)
[The prescription registry and abuse of pregabalin]
Tidsskr Nor Laegeforen, 131 (3), 223
DOI 10.4045/tidsskr.10.1328, PubMed 21304565
Landmark CJ, Johannessen SI (2011)
Safety aspects of antiepileptic drugs--focus on pharmacovigilance
Pharmacoepidemiol Drug Saf, 21 (1), 11-20
DOI 10.1002/pds.2269, PubMed 22069221
Landmark CJ, Larsson PG, Rytter E, Johannessen SI (2011)
[Clarification about pregabalin and the Norwegian Prescription Database]
Tidsskr Nor Laegeforen, 131 (8), 800-1
DOI 10.4045/tidsskr.11.0292, PubMed 21556068
Mekhaiel DN, Czajkowsky DM, Andersen JT, Shi J, El-Faham M, Doenhoff M, McIntosh RS, Sandlie I, He J, Hu J, Shao Z, Pleass RJ (2011)
Polymeric human Fc-fusion proteins with modified effector functions
Sci Rep, 1, 124
DOI 10.1038/srep00124, PubMed 22355641
Müller KM, Tveteraas IH, Aasrum M, Ødegård J, Dawood M, Dajani O, Christoffersen T, Sandnes DL (2011)
Role of protein kinase C and epidermal growth factor receptor signalling in growth stimulation by neurotensin in colon carcinoma cells
BMC Cancer, 11, 421
DOI 10.1186/1471-2407-11-421, PubMed 21961726
Myhr K (2011)
BigPharma and unethical marketing of medicinal products
South Med Rev, 4 (2), 48
DOI 10.5655/smr.v4i2.1000, PubMed 23093891
Myhr K (2011)
Access to and price of medicines globally
Tidsskr Nor Laegeforen, 131 (20), 2019-21
DOI 10.4045/tidsskr.11.0744, PubMed 22016132
Narum S, Solhaug V, Myhr K, Johansen PW, Brørs O, Kringen MK (2011)
Warfarin-associated bleeding events and concomitant use of potentially interacting medicines reported to the Norwegian spontaneous reporting system
Br J Clin Pharmacol, 71 (2), 254-62
DOI 10.1111/j.1365-2125.2010.03827.x, PubMed 21219407
Opdal SH, Melien O, Hynnekleiv T, Rognum TO (2011)
The brain-derived neutrophic factor val66met polymorphism and sudden unexpected infant death
Acta Paediatr, 100 (1), 86-9
DOI 10.1111/j.1651-2227.2010.01960.x, PubMed 20653606
Russell K, Smiseth OA, Gjesdal O, Qvigstad E, Norseng PA, Sjaastad I, Opdahl A, Skulstad H, Edvardsen T, Remme EW (2011)
Mechanism of prolonged electromechanical delay in late activated myocardium during left bundle branch block
Am J Physiol Heart Circ Physiol, 301 (6), H2334-43
DOI 10.1152/ajpheart.00644.2011, PubMed 21984549
Sæves I, Vethe NT, Bergan S (2011)
Quantification of 6 glucocorticoids in human plasma by liquid chromatography tandem mass spectrometry: method development, validation, and assessment of matrix effects
Ther Drug Monit, 33 (4), 402-10
DOI 10.1097/FTD.0b013e3182241799, PubMed 21743383
Stapleton NM, Andersen JT, Stemerding AM, Bjarnarson SP, Verheul RC, Gerritsen J, Zhao Y, Kleijer M, Sandlie I, de Haas M, Jonsdottir I, van der Schoot CE, Vidarsson G (2011)
Competition for FcRn-mediated transport gives rise to short half-life of human IgG3 and offers therapeutic potential
Nat Commun, 2, 599
DOI 10.1038/ncomms1608, PubMed 22186895
Vethe NT, Midtvedt K, Asberg A, Amundsen R, Bergan S (2011)
[Drug interactions and immunosuppression in organ transplant recipients]
Tidsskr Nor Laegeforen, 131 (20), 2000-3
DOI 10.4045/tidsskr.11.0138, PubMed 22016125

Publications 2010

Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS (2010)
Progress report on new antiepileptic drugs: a summary of the Tenth Eilat Conference (EILAT X)
Epilepsy Res, 92 (2-3), 89-124
DOI 10.1016/j.eplepsyres.2010.09.001, PubMed 20970964
Brudeli B, Moltzau LR, Andressen KW, Krobert KA, Klaveness J, Levy FO (2010)
Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists
Bioorg Med Chem, 18 (24), 8600-13
DOI 10.1016/j.bmc.2010.10.011, PubMed 21075638
Dehnes Y, Lamon S, Lönnberg M (2010)
Erythropoietin (EPO) immunoaffinity columns--a powerful tool for purifying EPO and its recombinant analogues
J Pharm Biomed Anal, 53 (4), 1028-32
DOI 10.1016/j.jpba.2010.06.017, PubMed 20656433
Elers J, Pedersen L, Henninge J, Lund TK, Hemmersbach P, Dalhoff K, Backer V (2010)
Blood and urinary concentrations of salbutamol in asthmatic subjects
Med Sci Sports Exerc, 42 (2), 244-9
DOI 10.1249/MSS.0b013e3181b2e87d, PubMed 19927035
Forli L, Bollerslev J, Simonsen S, Isaksen GA, Kvamsdal KE, Godang K, Gadeholt G, Pripp AH, Bjortuft O (2010)
Dietary vitamin K2 supplement improves bone status after lung and heart transplantation
Transplantation, 89 (4), 458-64
DOI 10.1097/TP.0b013e3181c46b69, PubMed 20177349
Gjerde H, Øiestad EL, Øiestad ÅM, Langødegård M, Gustavsen I, Hjelmeland K, Bernard JP, Christophersen AS (2010)
Comparison of zopiclone concentrations in oral fluid sampled with Intercept(®) oral specimen collection device and Statsure Saliva Sampler™ and concentrations in blood
J Anal Toxicol, 34 (9), 590-3
DOI 10.1093/jat/34.9.590, PubMed 21073813
Hemmersbach P, Grosse J (2010)
Nandrolone: a multi-faceted doping agent
Handb Exp Pharmacol (195), 127-54
DOI 10.1007/978-3-540-79088-4_6, PubMed 20020363
Henninge J, Pepaj M, Hullstein I, Hemmersbach P (2010)
Identification of CJC-1295, a growth-hormone-releasing peptide, in an unknown pharmaceutical preparation
Drug Test Anal, 2 (11-12), 647-50
DOI 10.1002/dta.233, PubMed 21204297
Holmen OL, Romundstad S, Melien O (2010)
Association between the G protein β3 subunit C825T polymorphism and the occurrence of cardiovascular disease in hypertensives: The Nord-Trøndelag Health Study (HUNT)
Am J Hypertens, 23 (10), 1121-7
DOI 10.1038/ajh.2010.121, PubMed 20539277
Johannessen SI, Landmark CJ (2010)
Antiepileptic drug interactions - principles and clinical implications
Curr Neuropharmacol, 8 (3), 254-67
DOI 10.2174/157015910792246254, PubMed 21358975
Karouni M, Arulthas S, Larsson PG, Rytter E, Johannessen SI, Landmark CJ (2010)
Psychiatric comorbidity in patients with epilepsy: a population-based study
Eur J Clin Pharmacol, 66 (11), 1151-60
DOI 10.1007/s00228-010-0861-y, PubMed 20669014
Kringen MK, Haug KB, Grimholt RM, Stormo C, Narum S, Opdal MS, Fosen JT, Piehler AP, Johansen PW, Seljeflot I, Berg JP, Brørs O (2010)
Genetic variation of VKORC1 and CYP4F2 genes related to warfarin maintenance dose in patients with myocardial infarction
J Biomed Biotechnol, 2011, 739751
DOI 10.1155/2011/739751, PubMed 21127708
Kringen MK, Narum S, Lygren I, Seljeflot I, Sandset PM, Trøseid AM, Johansen PW, Brørs O, Holthe MR (2010)
Reduced platelet function and role of drugs in acute gastrointestinal bleeding
Basic Clin Pharmacol Toxicol, 108 (3), 194-201
DOI 10.1111/j.1742-7843.2010.00643.x, PubMed 21118353
Lönnberg M, Dehnes Y, Drevin M, Garle M, Lamon S, Leuenberger N, Quach T, Carlsson J (2010)
Rapid affinity purification of erythropoietin from biological samples using disposable monoliths
J Chromatogr A, 1217 (45), 7031-7
DOI 10.1016/j.chroma.2010.09.034, PubMed 20926083
Overturf K, LaPatra S, Towner R, Campbell N, Narum S (2010)
Relationships between growth and disease resistance in rainbow trout, Oncorhynchus mykiss (Walbaum)
J Fish Dis, 33 (4), 321-9
DOI 10.1111/j.1365-2761.2009.01124.x, PubMed 20059633
Romundstad S, Melien O, Holmen J (2010)
The G protein β3 subunit C825T polymorphism is associated with microalbuminuria in hypertensive women and cardiovascular disease in hypertensive men
Am J Hypertens, 23 (10), 1114-20
DOI 10.1038/ajh.2010.131, PubMed 20577224
Sørensen O, Andersen A, Olsen H, Alexandr K, Ekstrøm PO, Giercksky KE, Flatmark K (2010)
Validation and use of microdialysis for determination of pharmacokinetic properties of the chemotherapeutic agent mitomycin C - an experimental study
BMC Cancer, 10, 469
DOI 10.1186/1471-2407-10-469, PubMed 20809961
Vethe NT, Gjerdalen LC, Bergan S (2010)
Determination of cyclosporine, tacrolimus, sirolimus and everolimus by liquid chromatography coupled to electrospray ionization and tandem mass spectrometry: assessment of matrix effects and assay performance
Scand J Clin Lab Invest, 70 (8), 583-91
DOI 10.3109/00365513.2010.531141, PubMed 21039189
Westergren T (2010)
An introduction to hospital pharmacy in Norway
EJHP Pract., 16 (5), 38-39
Westergren T (2010)
Hospital pharmacists' role in adverse drug reaction reporting
EJHP Pract., 16 (4), 10-11

Publications 2009

Gudex C, Hoffmann M, Brørs O, Dahlqvist R (2009)
[GPs' perceptions of the Institute for Rational Pharmacotherapy]
Ugeskr Laeger, 171 (7), 522-6
PubMed 19210936
Holager T, Lagerløv P, Helseth S, Rosvold EO (2009)
[Attitudes to over-the-counter analgesics among 15-16 year-old teenagers]
Tidsskr Nor Laegeforen, 129 (15), 1451-4
DOI 10.4045/tidsskr.08.0513, PubMed 19690593
Johannessen Landmark C, Larsson PG, Rytter E, Johannessen SI (2009)
Antiepileptic drugs in epilepsy and other disorders--a population-based study of prescriptions
Epilepsy Res, 87 (1), 31-9
DOI 10.1016/j.eplepsyres.2009.07.005, PubMed 19679449
Lagerløv P, Holager T, Helseth S, Rosvold EO (2009)
[Self-medication with over-the-counter analgesics among 15-16 year-old teenagers]
Tidsskr Nor Laegeforen, 129 (15), 1447-50
DOI 10.4045/tidsskr.09.32759, PubMed 19690592
Lehne G, Grasmo-Wendler UH, Berner JM, Meza-Zepeda LA, Adamsen BL, Flack A, Reiner A, Clausen OP, Hovig E, Myklebost O (2009)
Upregulation of stem cell genes in multidrug resistant K562 leukemia cells
Leuk Res, 33 (10), 1379-85
DOI 10.1016/j.leukres.2009.03.028, PubMed 19394083
Myhr K (2009)
[Noscapine and warfarin--a potentially dangerous interaction]
Tidsskr Nor Laegeforen, 129 (6), 540
DOI 10.4045/tidsskr.09.0123, PubMed 19282895
Thevis M, Hemmersbach P, Geyer H, Schänzer W (2009)
[Doping in disabled sports. Doping control activities at the Paralympic Games 1984-2008 and in Germany 1992-2008]
Med Klin (Munich), 104 (12), 918-24
DOI 10.1007/s00063-009-1190-8, PubMed 20039158
Westergren T, Kalikstad B (2009)
Dosage and formulation issues: oral vitamin E therapy in children
Eur J Clin Pharmacol, 66 (2), 109-18
DOI 10.1007/s00228-009-0729-1, PubMed 19823814

Publications 2008

Dajani OF, Meisdalen K, Guren TK, Aasrum M, Tveteraas IH, Lilleby P, Thoresen GH, Sandnes D, Christoffersen T (2008)
Prostaglandin E2 upregulates EGF-stimulated signaling in mitogenic pathways involving Akt and ERK in hepatocytes
J Cell Physiol, 214 (2), 371-80
DOI 10.1002/jcp.21205, PubMed 17654493
Eikemo H, Skomedal T, Levy FO, Osnes JB (2008)
Calculating reaction rate constants and estimating the efficacy of selective enzyme inhibitors
Anal Biochem, 383 (2), 323-5
DOI 10.1016/j.ab.2008.09.011, PubMed 18831958
Gudmundsdottir H, Brørs O, Os I (2008)
[Metformin should not be used by patients with reduced renal function]
Tidsskr Nor Laegeforen, 128 (8), 936-7
PubMed 18431417
Haug KBF, Sharikabad MN, Kringen MK, Narum S, Sjaatil ST, Johansen PW, Kierulf P, Seljeflot I, Arnesen H, Brørs O (2008)
Warfarin dose and INR related to genotypes of CYP2C9 and VKORC1 in patients with myocardial infarction
Thromb J, 6, 7
DOI 10.1186/1477-9560-6-7, PubMed 18559094
Hemmersbach P (2008)
History of mass spectrometry at the Olympic Games
J Mass Spectrom, 43 (7), 839-53
DOI 10.1002/jms.1445, PubMed 18570181
Heyerdahl F, Hovda KE, Bjornaas MA, Brørs O, Ekeberg O, Jacobsen D (2008)
Clinical assessment compared to laboratory screening in acutely poisoned patients
Hum Exp Toxicol, 27 (1), 73-9
DOI 10.1177/0960327107087800, PubMed 18480152
Hofstad B, Nesbakken A, Eritsland J, Brørs O, Sandset PM (2008)
[Should platelet inhibitors be discontinued before gastrointestinal endoscopy?]
Tidsskr Nor Laegeforen, 128 (21), 2440-2
PubMed 19096466
Johannessen Landmark C, Johannessen SI (2008)
Pharmacological management of epilepsy: recent advances and future prospects
Drugs, 68 (14), 1925-39
DOI 10.2165/00003495-200868140-00001, PubMed 18778117
Juul A, Sørensen K, Aksglaede L, Garn I, Rajpert-De Meyts E, Hullstein I, Hemmersbach P, Ottesen AM (2008)
A common deletion in the uridine diphosphate glucuronyltransferase (UGT) 2B17 gene is a strong determinant of androgen excretion in healthy pubertal boys
J Clin Endocrinol Metab, 94 (3), 1005-11
DOI 10.1210/jc.2008-1984, PubMed 19088161
Landmark CJ, Johannessen SI (2008)
Modifications of antiepileptic drugs for improved tolerability and efficacy
Perspect Medicin Chem, 2, 21-39
PubMed 19787095
Lindenberger M, Olsen H, Länne T (2008)
Lower capacitance response and capillary fluid absorption in women to defend central blood volume in response to acute hypovolemic circulatory stress
Am J Physiol Heart Circ Physiol, 295 (2), H867-73
DOI 10.1152/ajpheart.00332.2008, PubMed 18586891
Meen O, Brosstad F, Khiabani H, Gjertsen E, Lauritsen ME, Pedersen TM, Bjørnsen S, Schjelderup NM, Ameln W, Ng EC, Wettergreen M, Siddique SP, Erikssen G (2008)
No case of COX-1-related aspirin resistance found in 289 patients with symptoms of stable CHD remitted for coronary angiography
Scand J Clin Lab Invest, 68 (3), 185-91
DOI 10.1080/00365510701601673, PubMed 17934975
Nakken KO, Johannessen SI (2008)
[Seizure exacerbation caused by antiepileptic drugs]
Tidsskr Nor Laegeforen, 128 (18), 2052-5
PubMed 18846119
Nase G, Helm PJ, Oguchi T, Nilsson LNG, Lannfelt L, Ottersen OP, Torp R (2008)
Local impact of perivascular plaques on cerebral blood flow dynamics in a transgenic mouse model of Alzheimer's disease
PROC SPIE, 6860, 686022
Reine PA, Kongsgaard UE, Andersen A, Thøgersen AK, Olsen H (2008)
Infusion of albumin attenuates changes in serum protein binding of drugs in surgical patients compared with volume replacement with HAES
Acta Anaesthesiol Scand, 52 (3), 406-12
DOI 10.1111/j.1399-6576.2007.01555.x, PubMed 18269390
Reppe LA, Stenberg-Nilsen H, Harg P, Hegge AB, Lillefloth AK, Buajordet I (2008)
[Adverse events related to substitution of generic products in Norway 2005]
Tidsskr Nor Laegeforen, 128 (23), 2696-700
PubMed 19079413
Søland TM, Husvik C, Koppang HS, Boysen M, Sandvik L, Clausen OP, Christoffersen T, Bryne M (2008)
A study of phosphorylated ERK1/2 and COX-2 in early stage (T1-T2) oral squamous cell carcinomas
J Oral Pathol Med, 37 (9), 535-42
DOI 10.1111/j.1600-0714.2008.00656.x, PubMed 18284542

Publications 2007

Andersen JT, Sandlie I (2007)
A receptor-mediated mechanism to support clinical observation of altered albumin variants
Clin Chem, 53 (12), 2216
DOI 10.1373/clinchem.2007.097071, PubMed 18267931
Birkeland JA, Swift F, Tovsrud N, Enger U, Lunde PK, Qvigstad E, Levy FO, Sejersted OM, Sjaastad I (2007)
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes
Am J Physiol Heart Circ Physiol, 293 (4), H2367-76
DOI 10.1152/ajpheart.01375.2006, PubMed 17660386
Brattelid T, Tveit K, Birkeland JA, Sjaastad I, Qvigstad E, Krobert KA, Hussain RI, Skomedal T, Osnes JB, Levy FO (2007)
Expression of mRNA encoding G protein-coupled receptors involved in congestive heart failure--a quantitative RT-PCR study and the question of normalisation
Basic Res Cardiol, 102 (3), 198-208
DOI 10.1007/s00395-007-0648-1, PubMed 17370034
Brunsvig PF, Andersen A, Aamdal S, Kristensen V, Olsen H (2007)
Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy
BMC Cancer, 7, 197
DOI 10.1186/1471-2407-7-197, PubMed 17956601
Buajordet I, Laake K, Brørs O (2007)
[Can the screening of blood samples identify adverse drug reactions?]
Tidsskr Nor Laegeforen, 127 (12), 1637-9
PubMed 17571101
Gedde-Dahl A, Harg P, Stenberg-Nilsen H, Buajordet M, Granas AG, Horn AM (2007)
Characteristics and quality of adverse drug reaction reports by pharmacists in Norway
Pharmacoepidemiol Drug Saf, 16 (9), 999-1005
DOI 10.1002/pds.1400, PubMed 17457794
Granas AG, Buajordet M, Stenberg-Nilsen H, Harg P, Horn AM (2007)
Pharmacists' attitudes towards the reporting of suspected adverse drug reactions in Norway
Pharmacoepidemiol Drug Saf, 16 (4), 429-34
DOI 10.1002/pds.1298, PubMed 16953518
Gustavsen I, Hjelmeland K, Bachs L, Mørland J (2007)
[Substance abuse can cause stroke]
Tidsskr Nor Laegeforen, 127 (10), 1401; author reply 1401-2
PubMed 17520003
Landmark CJ, Rytter E, Johannessen SI (2007)
Clinical use of antiepileptic drugs at a referral centre for epilepsy
Seizure, 16 (4), 356-64
DOI 10.1016/j.seizure.2007.02.006, PubMed 17420145
Landmark KE, Johansen PW, Johnson JA, Johansen B, Uran S, Skotland T (2007)
Pharmacokinetics of perfluorobutane following intravenous bolus injection and continuous infusion of sonazoid in healthy volunteers and in patients with reduced pulmonary diffusing capacity
Ultrasound Med Biol, 34 (3), 494-501
DOI 10.1016/j.ultrasmedbio.2007.09.019, PubMed 18096304
Melien O (2007)
Heterotrimeric G proteins and disease
Methods Mol Biol, 361, 119-44
DOI 10.1385/1-59745-208-4:119, PubMed 17172709
Molden E, Westergren T (2007)
[Interaction risk with statin switch]
Tidsskr Nor Laegeforen, 127 (4), 428-31
PubMed 17304269
Morkeberg J, Lundby C, Nissen-Lie G, Nielsen TK, Hemmersbach P, Damsgaard R (2007)
Detection of darbepoetin alfa misuse in urine and blood: a preliminary investigation
Med Sci Sports Exerc, 39 (10), 1742-7
DOI 10.1249/mss.0b013e31811e9d55, PubMed 17909401
Schulte G, Levy FO (2007)
Novel aspects of G-protein-coupled receptor signalling--different ways to achieve specificity
Acta Physiol (Oxf), 190 (1), 33-8
DOI 10.1111/j.1365-201X.2007.01696.x, PubMed 17428230
Sioud M, Melien O (2007)
Treatment options and individualized medicine
Methods Mol Biol, 361, 327-40
DOI 10.1385/1-59745-208-4:327, PubMed 17172721
Torfoss D, Høiby EA, Tangen JM, Holte H, Bø K, Meyer P, Grøttum K, Weyde K, Lauritzsen GF, Sandstad B, Jacobsen AB, Olsen H, Kvaløy S (2007)
Tobramycin once versus three times daily, given with penicillin G, to febrile neutropenic cancer patients in Norway: a prospective, randomized, multicentre trial
J Antimicrob Chemother, 59 (4), 711-7
DOI 10.1093/jac/dkm003, PubMed 17327294
Vinge LE, Andressen KW, Attramadal T, Andersen GØ, Ahmed MS, Peppel K, Koch WJ, Freedman NJ, Levy FO, Skomedal T, Osnes JB, Attramadal H (2007)
Substrate specificities of g protein-coupled receptor kinase-2 and -3 at cardiac myocyte receptors provide basis for distinct roles in regulation of myocardial function
Mol Pharmacol, 72 (3), 582-91
DOI 10.1124/mol.107.035766, PubMed 17573483
Westergren T, Johansson P, Molden E (2007)
Probable warfarin-simvastatin interaction
Ann Pharmacother, 41 (7), 1292-5
DOI 10.1345/aph.1K167, PubMed 17565042

Publications 2006

Andersen A, Warren DJ, Brunsvig PF, Aamdal S, Kristensen GB, Olsen H (2006)
High sensitivity assays for docetaxel and paclitaxel in plasma using solid-phase extraction and high-performance liquid chromatography with UV detection
BMC Clin Pharmacol, 6, 2
DOI 10.1186/1472-6904-6-2, PubMed 16412237
Bialer M, Johannessen SI, Kupferberg HJ, Levy RH, Perucca E, Tomson T (2006)
Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII)
Epilepsy Res, 73 (1), 1-52
DOI 10.1016/j.eplepsyres.2006.10.008, PubMed 17158031
Birkeland JA, Sjaastad I, Brattelid T, Qvigstad E, Moberg ER, Krobert KA, Bjørnerheim R, Skomedal T, Sejersted OM, Osnes JB, Levy FO (2006)
Effects of treatment with a 5-HT4 receptor antagonist in heart failure
Br J Pharmacol, 150 (2), 143-52
DOI 10.1038/sj.bjp.0706966, PubMed 17160012
Gorovetz M, Baekelandt M, Berner A, Trope' CG, Davidson B, Reich R (2006)
The clinical role of phospholipase A2 isoforms in advanced-stage ovarian carcinoma
Gynecol Oncol, 103 (3), 831-40
DOI 10.1016/j.ygyno.2006.06.042, PubMed 16919315
Gotlieb WH, Bruchim I, Ben-Baruch G, Davidson B, Zeltser A, Andersen A, Olsen H (2006)
Doxorubicin levels in the serum and ascites of patients with ovarian cancer
Eur J Surg Oncol, 33 (2), 213-5
DOI 10.1016/j.ejso.2006.11.006, PubMed 17174514
Hauge Opdal S, Melien Ø, Rootwelt H, Vege A, Arnestad M, Ole Rognum T (2006)
The G protein beta3 subunit 825C allele is associated with sudden infant death due to infection
Acta Paediatr, 95 (9), 1129-32
DOI 10.1080/08035250600580529, PubMed 16938762
Hemmersbach P, Hågensen Jetne AH, Lund HS (2006)
Determination of urinary norandrosterone excretion in females during one menstrual cycle by gas chromatography/mass spectrometry
Biomed Chromatogr, 20 (8), 710-7
DOI 10.1002/bmc.586, PubMed 16229056
Kalikstad B, Westergren T (2006)
[Drugs for children--when temporary solutions become routine]
Tidsskr Nor Laegeforen, 126 (7), 930-2
PubMed 16554887
Kaumann AJ, Levy FO (2006)
Fading of 5-HT4 receptor-mediated inotropic responses to 5-hydroxytryptamine is caused by phosphodiesterase activity in porcine atrium
Br J Pharmacol, 147 (2), 128-30
DOI 10.1038/sj.bjp.0706501, PubMed 16331292
Kaumann AJ, Levy FO (2006)
5-hydroxytryptamine receptors in the human cardiovascular system
Pharmacol Ther, 111 (3), 674-706
DOI 10.1016/j.pharmthera.2005.12.004, PubMed 16960982
Krobert KA, Andressen KW, Levy FO (2006)
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor
Eur J Pharmacol, 532 (1-2), 1-10
DOI 10.1016/j.ejphar.2005.11.039, PubMed 16487959
Larsen KO, Sjaastad I, Svindland A, Krobert KA, Skjønsberg OH, Christensen G (2006)
Alveolar hypoxia induces left ventricular diastolic dysfunction and reduces phosphorylation of phospholamban in mice
Am J Physiol Heart Circ Physiol, 291 (2), H507-16
DOI 10.1152/ajpheart.00862.2005, PubMed 16582020
Lehne G, Haneberg B, Gaustad P, Johansen PW, Preus H, Abrahamsen TG (2006)
Oral administration of a new soluble branched beta-1,3-D-glucan is well tolerated and can lead to increased salivary concentrations of immunoglobulin A in healthy volunteers
Clin Exp Immunol, 143 (1), 65-9
DOI 10.1111/j.1365-2249.2005.02962.x, PubMed 16367935
Myhr K (2006)
[Atomoxetine--an addition]
Tidsskr Nor Laegeforen, 126 (4), 480
PubMed 16477295
Westergren T, Kalikstad B (2006)
[Vitamin E mixture for children--treatment with a blindfold?]
Tidsskr Nor Laegeforen, 126 (7), 902-4
PubMed 16554880

Publications 2005

Andressen KW, Norum JH, Levy FO, Krobert KA (2005)
Activation of adenylyl cyclase by endogenous G(s)-coupled receptors in human embryonic kidney 293 cells is attenuated by 5-HT(7) receptor expression
Mol Pharmacol, 69 (1), 207-15
DOI 10.1124/mol.105.015396, PubMed 16189297
Berntzen G, Lunde E, Flobakk M, Andersen JT, Lauvrak V, Sandlie I (2005)
Prolonged and increased expression of soluble Fc receptors, IgG and a TCR-Ig fusion protein by transiently transfected adherent 293E cells
J Immunol Methods, 298 (1-2), 93-104
DOI 10.1016/j.jim.2005.01.002, PubMed 15847800
Cappelen A, Johansen PW (2005)
[Doping preparations list and exceptions based on medical reasons]
Tidsskr Nor Laegeforen, 125 (2), 197-8
PubMed 15665899
Fjeldheim AK, Høvring PI, Løseth OP, Johansen PW, Glover JC, Matre V, Olstad OK, Reppe S, Gordeladze JO, Walaas SI, Gautvik KM (2005)
Thyrotrophin-releasing hormone receptor 1 and prothyrotrophin-releasing hormone mRNA expression in the central nervous system are regulated by suckling in lactating rats
Eur J Endocrinol, 152 (5), 791-803
DOI 10.1530/eje.1.01902, PubMed 15879366
Grosse J, Anielski P, Hemmersbach P, Lund H, Mueller RK, Rautenberg C, Thieme D (2005)
Formation of 19-norsteroids by in situ demethylation of endogenous steroids in stored urine samples
Steroids, 70 (8), 499-506
DOI 10.1016/j.steroids.2005.01.005, PubMed 15894033
Hartmann S, Brørs O, Bock J, Blomhoff R, Bausch J, Wiegand UW, Hartmann D, Hornig DH (2005)
Exposure to retinoic acids in non-pregnant women following high vitamin A intake with a liver meal
Int J Vitam Nutr Res, 75 (3), 187-94
DOI 10.1024/0300-9831.75.3.187, PubMed 16028634
Hartmann S, Brørs O, Bock J, Blomhoff R, Bausch J, Wiegand UW, Hartmann D, Hornig DH (2005)
Exposure to retinyl esters, retinol, and retinoic acids in non-pregnant women following increasing single and repeated oral doses of vitamin A
Ann Nutr Metab, 49 (3), 155-64
DOI 10.1159/000086879, PubMed 16006784
Johannessen SI (2005)
[Therapeutic monitoring of antiepileptic drugs]
Zh Nevrol Psikhiatr Im S S Korsakova, 105 (12), 56-9
PubMed 16447570
Krobert KA, Brattelid T, Levy FO, Kaumann AJ (2005)
Prucalopride is a partial agonist through human and porcine atrial 5-HT4 receptors: comparison with recombinant human 5-HT4 splice variants
Naunyn Schmiedebergs Arch Pharmacol, 371 (6), 473-9
DOI 10.1007/s00210-005-1068-0, PubMed 16012870
Kvan E, Narum S (2005)
[Long-cycle oral contraceptives--a progress?]
Tidsskr Nor Laegeforen, 125 (16), 2202-3
PubMed 16138136
Melien Ø, Skaali T, Myhr K, Brørs O (2005)
Venlafaxine and asthma
Nord J Psychiatry, 59 (6), 538-40
DOI 10.1080/08039480500363595, PubMed 16316911
Morag RM, DeSouza S, Steen PA, Salem A, Harris M, Ohnstad O, Fosen JT, Brenner BE (2005)
Performing procedures on the newly deceased for teaching purposes: what if we were to ask?
Arch Intern Med, 165 (1), 92-6
DOI 10.1001/archinte.165.1.92, PubMed 15642881
Norum JH, Méthi T, Mattingly RR, Levy FO (2005)
Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells
FEBS J, 272 (9), 2304-16
DOI 10.1111/j.1742-4658.2005.04658.x, PubMed 15853814
Olsen V, Gustavsen I, Bramness JG, Hasvold I, Karinen R, Christophersen AS, Mørland J (2005)
The concentrations, appearance and taste of nine sedating drugs dissolved in four different beverages
Forensic Sci Int, 151 (2-3), 171-5
DOI 10.1016/j.forsciint.2005.01.017, PubMed 15939149
Qvigstad E, Brattelid T, Sjaastad I, Andressen KW, Krobert KA, Birkeland JA, Sejersted OM, Kaumann AJ, Skomedal T, Osnes JB, Levy FO (2005)
Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure
Cardiovasc Res, 65 (4), 869-78
DOI 10.1016/j.cardiores.2004.11.017, PubMed 15721867
Qvigstad E, Sjaastad I, Brattelid T, Nunn C, Swift F, Birkeland JA, Krobert KA, Andersen GØ, Sejersted OM, Osnes JB, Levy FO, Skomedal T (2005)
Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart
Circ Res, 97 (3), 268-76
DOI 10.1161/01.RES.0000176970.22603.8d, PubMed 16002744
Ranhoff AH, Brørs O (2005)
[Drugs which can cause delirium among the elderly]
Tidsskr Nor Laegeforen, 125 (17), 2366-7
PubMed 16151497

Publications 2004

Bialer M, Johannessen SI, Kupferberg HJ, Levy RH, Perucca E, Tomson T (2004)
Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII)
Epilepsy Res, 61 (1-3), 1-48
DOI 10.1016/j.eplepsyres.2004.07.010, PubMed 15570674
Brattelid T, Kvingedal AM, Krobert KA, Andressen KW, Bach T, Hystad ME, Kaumann AJ, Levy FO (2004)
Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i)
Naunyn Schmiedebergs Arch Pharmacol, 369 (6), 616-28
DOI 10.1007/s00210-004-0919-4, PubMed 15118808
Brattelid T, Qvigstad E, Lynham JA, Molenaar P, Aass H, Geiran O, Skomedal T, Osnes JB, Levy FO, Kaumann AJ (2004)
Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure
Naunyn Schmiedebergs Arch Pharmacol, 370 (3), 157-66
DOI 10.1007/s00210-004-0963-0, PubMed 15365689
Brodtkorb E, Klees TM, Nakken KO, Lossius R, Johannessen SI (2004)
Levetiracetam in adult patients with and without learning disability: focus on behavioral adverse effects
Epilepsy Behav, 5 (2), 231-5
DOI 10.1016/j.yebeh.2003.12.005, PubMed 15123025
Flaten MA, Simonsen T, Zahlsen K, Aamo T, Sager G, Olsen H (2004)
Stimulant and relaxant drugs combined with stimulant and relaxant information: a study of active placebo
Psychopharmacology (Berl), 176 (3-4), 426-34
DOI 10.1007/s00213-004-1886-7, PubMed 15549277
Gadeholt G (2004)
[Blood analysis of vitamin K]
Tidsskr Nor Laegeforen, 124 (24), 3261; author reply 3261-2
PubMed 15608790
Lagerløv P, Holager T, Westergren T, Aamodt G (2004)
[Paracetamol to preschool children--indications and cultural background]
Tidsskr Nor Laegeforen, 124 (16), 2080-3
PubMed 15334118
Lagerløv P, Holager T, Westergren T, Aamodt G (2004)
[The use of paracetamol and antibiotics among preschool children]
Tidsskr Nor Laegeforen, 124 (12), 1620-3
PubMed 15229705
Nissen-Lie G, Birkeland K, Hemmersbach P, Skibeli V (2004)
Serum sTfR levels may indicate charge profiling of urinary r-hEPO in doping control
Med Sci Sports Exerc, 36 (4), 588-93
DOI 10.1249/01.mss.0000121953.90379.a7, PubMed 15064585
Øie E, Vinge LE, Andersen GØ, Yndestad A, Krobert KA, Sandberg C, Ahmed MS, Haug T, Levy FO, Skomedal T, Attramadal H (2004)
RAMP2 and RAMP3 mRNA levels are increased in failing rat cardiomyocytes and associated with increased responsiveness to adrenomedullin
J Mol Cell Cardiol, 38 (1), 145-51
DOI 10.1016/j.yjmcc.2004.10.009, PubMed 15623431
Olsen H, Andersen A, Nordbø A, Kongsgaard UE, Børmer OP (2004)
Pharmaceutical-grade albumin: impaired drug-binding capacity in vitro
BMC Clin Pharmacol, 4, 4
DOI 10.1186/1472-6904-4-4, PubMed 15046641
Sharikabad MN, Østbye KM, Brørs O (2004)
Effect of hydrogen peroxide on reoxygenation-induced Ca2+ accumulation in rat cardiomyocytes
Free Radic Biol Med, 37 (4), 531-8
DOI 10.1016/j.freeradbiomed.2004.05.002, PubMed 15256224
Skulberg KR, Skyberg K, Kruse K, Eduard W, Djupesland P, Levy F, Kjuus H (2004)
The effect of cleaning on dust and the health of office workers: an intervention study
Epidemiology, 15 (1), 71-8
DOI 10.1097/01.ede.0000101020.72399.37, PubMed 14712149
Tomson T, Beghi E, Sundqvist A, Johannessen SI (2004)
Medical risks in epilepsy: a review with focus on physical injuries, mortality, traffic accidents and their prevention
Epilepsy Res, 60 (1), 1-16
DOI 10.1016/j.eplepsyres.2004.05.004, PubMed 15279865
Verheggen R, Meier A, Werner I, Wienekamp A, Kruschat T, Brattelid T, Levy FO, Kaumann A (2004)
Functional 5-HT receptors in human occipital artery
Naunyn Schmiedebergs Arch Pharmacol, 369 (4), 391-401
DOI 10.1007/s00210-004-0878-9, PubMed 15007537

Publications 2003

Ahmed MS, Øie E, Vinge LE, Yndestad A, Andersen G GØ, Andersson Y, Attramadal T, Attramadal H (2003)
Induction of myocardial biglycan in heart failure in rats--an extracellular matrix component targeted by AT(1) receptor antagonism
Cardiovasc Res, 60 (3), 557-68
DOI 10.1016/j.cardiores.2003.08.017, PubMed 14659801
Andersen GØ, Skomedal T, Enger M, Fidjeland A, Brattelid T, Levy FO, Osnes JB (2003)
Alpha1-AR-mediated activation of NKCC in rat cardiomyocytes involves ERK-dependent phosphorylation of the cotransporter
Am J Physiol Heart Circ Physiol, 286 (4), H1354-60
DOI 10.1152/ajpheart.00549.2003, PubMed 14630635
Bruheim S, Krobert KA, Andressen KW, Levy FO (2003)
Unaltered agonist potency upon inducible 5-HT7(a) but not 5-HT4(b) receptor expression indicates agonist-independent association of 5-HT7(a) receptor and Gs
Recept Channels, 9 (2), 107-16
DOI 10.1080/10606820308245, PubMed 12916471
Jensen J, Sharikabad MN, Østbye KM, Melien Ø, Brørs O (2003)
Evidence that nitroprusside stimulates glucose uptake in isolated rat cardiomyocytes via mitogen-activated protein kinase
Arch Physiol Biochem, 111 (3), 239-45
DOI 10.1076/apab.111.3.239.23463, PubMed 14972746
Johannessen CU, Johannessen SI (2003)
Valproate: past, present, and future
CNS Drug Rev, 9 (2), 199-216
DOI 10.1111/j.1527-3458.2003.tb00249.x, PubMed 12847559
Lagerløv P, Helseth S, Holager T (2003)
Childhood illnesses and the use of paracetamol (acetaminophen): a qualitative study of parents' management of common childhood illnesses
Fam Pract, 20 (6), 717-23
DOI 10.1093/fampra/cmg616, PubMed 14701898
Lindberger M, Luhr O, Johannessen SI, Larsson S, Tomson T (2003)
Serum concentrations and effects of gabapentin and vigabatrin: observations from a dose titration study
Ther Drug Monit, 25 (4), 457-62
DOI 10.1097/00007691-200308000-00007, PubMed 12883229
Mariero Klees T, Brodtkorb E, Nakken KO, Lossius R, Johannessen SI (2003)
[Levetiracetam in the treatment of epilepsy]
Tidsskr Nor Laegeforen, 123 (11), 1539-41
PubMed 12822020
Melien Ø, Johansen PW, Westergren T, Rugstad HE (2003)
[Vitamin K in food and the effect of warfarin]
Tidsskr Nor Laegeforen, 123 (13-14), 1862-3
PubMed 12830268
Nakken KO, Eriksson AS, Lossius R, Johannessen SI (2003)
A paradoxical effect of levetiracetam may be seen in both children and adults with refractory epilepsy
Seizure, 12 (1), 42-6
DOI 10.1016/s1059131102001723, PubMed 12495648
Perucca E, Johannessen SI (2003)
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
Epileptic Disord, 5 Suppl 1, S17-26
PubMed 12915337
Rytter E, Johannessen SI, Nakken KO (2003)
[Oral contraceptives in women with epilepsy]
Tidsskr Nor Laegeforen, 123 (12), 1674-5
PubMed 12821987
Skibeli V, Nissen-Lie G, Torjesen P (2003)
Response: Inherent charge properties of the isolated sugar parts of human serum erythropoietin
Blood, 101 (3), 1204-1205
Stenberg-Nilsen H (2003)
[Use of fluconazole during pregnancy]
Tidsskr Nor Laegeforen, 123 (9), 1209-10
PubMed 12789793
Waal H, Aamodt Ø, Olsen H (2003)
[Use of naltrexone in the treatment of young drug addicts]
Tidsskr Nor Laegeforen, 123 (12), 1662-4
PubMed 12821983
Wehner F, Olsen H, Tinel H, Kinne-Saffran E, Kinne RK (2003)
Cell volume regulation: osmolytes, osmolyte transport, and signal transduction
Rev Physiol Biochem Pharmacol, 148, 1-80
DOI 10.1007/s10254-003-0009-x, PubMed 12687402
Williams J, Bialer M, Johannessen SI, Krämer G, Levy R, Mattson RH, Perucca E, Patsalos PN, Wilson JF (2003)
Interlaboratory variability in the quantification of new generation antiepileptic drugs based on external quality assessment data
Epilepsia, 44 (1), 40-5
DOI 10.1046/j.1528-1157.2003.26702.x, PubMed 12581228

Publications 2002

Bialer M, Johannessen SI, Kupferberg HJ, Levy RH, Loiseau P, Perucca E (2002)
Progress report on new antiepileptic drugs: a summary of the Sixth Eilat Conference (EILAT VI)
Epilepsy Res, 51 (1-2), 31-71
DOI 10.1016/s0920-1211(02)00106-7, PubMed 12350382
Buajordet I, Wesenberg F, Brørs O, Langslet A (2002)
Adverse drug events in children during hospitalization and after discharge in a Norwegian university hospital
Acta Paediatr, 91 (1), 88-94
DOI 10.1080/080352502753458021, PubMed 11883826
Dahm AE, Brørs O (2002)
[Phenytoin poisoning caused by interaction with ticlopidine]
Tidsskr Nor Laegeforen, 122 (3), 278-80
PubMed 11894596
Heldal D, Brinch L, Tjønnfjord G, Solheim BG, Egeland T, Gadeholt G, Albrechtsen D, Aamodt G, Evensen SA (2002)
Donation of stem cells from blood or bone marrow: results of a randomised study of safety and complaints
Bone Marrow Transplant, 29 (6), 479-86
DOI 10.1038/sj.bmt.1703418, PubMed 11960266
Jensen J, Brennesvik EO, Bergersen H, Oseland H, Jebens E, Brørs O (2002)
Quantitative determination of cell surface beta-adrenoceptors in different rat skeletal muscles
Pflugers Arch, 444 (1-2), 213-9
DOI 10.1007/s00424-002-0793-1, PubMed 11976934
Johansen PW, Bergan S, Rootwelt H, Kvittingen EA, Rugstad HE (2002)
[Individualized pharmacotherapy based on cytochrome P-450 (CYP) genotyping]
Tidsskr Nor Laegeforen, 122 (29), 2781-3
PubMed 12523145
Krobert KA, Levy FO (2002)
The human 5-HT7 serotonin receptor splice variants: constitutive activity and inverse agonist effects
Br J Pharmacol, 135 (6), 1563-71
DOI 10.1038/sj.bjp.0704588, PubMed 11906971
Krook AL, Brørs O, Dahlberg J, Grouff K, Magnus P, Røysamb E, Waal H (2002)
A placebo-controlled study of high dose buprenorphine in opiate dependents waiting for medication-assisted rehabilitation in Oslo, Norway
Addiction, 97 (5), 533-42
DOI 10.1046/j.1360-0443.2002.00090.x, PubMed 12033654
Lehne G, Sørensen DR, Tjønnfjord GE, Beiske C, Hagve TA, Rugstad HE, Clausen OP (2002)
The cyclosporin PSC 833 increases survival and delays engraftment of human multidrug-resistant leukemia cells in xenotransplanted NOD-SCID mice
Leukemia, 16 (12), 2388-94
DOI 10.1038/sj.leu.2402663, PubMed 12454743
Melien O, Nilssen LS, Dajani OF, Sand KL, Iversen JG, Sandnes DL, Christoffersen T (2002)
Ca2+-mediated activation of ERK in hepatocytes by norepinephrine and prostaglandin F2 alpha: role of calmodulin and Src kinases
BMC Cell Biol, 3, 5
DOI 10.1186/1471-2121-3-5, PubMed 11914123
Molden E, Johansen PW, Bøe GH, Bergan S, Christensen H, Rugstad HE, Rootwelt H, Reubsaet L, Lehne G (2002)
Pharmacokinetics of diltiazem and its metabolites in relation to CYP2D6 genotype
Clin Pharmacol Ther, 72 (3), 333-42
DOI 10.1067/mcp.2002.127396, PubMed 12235455
Norum JH, Hart K, Levy FO (2002)
Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a)
J Biol Chem, 278 (5), 3098-104
DOI 10.1074/jbc.M206237200, PubMed 12446729
Olsen H, Gelvan A (2002)
Listeria monocytogenes demonstrated in cerebrospinal fluid in the absence of inflammatory cells: a case of fever and seizures in a 13-y-old boy
Scand J Infect Dis, 34 (9), 710-1
DOI 10.1080/00365540210147859, PubMed 12374374
Plo I, Lehne G, Beckstrøm KJ, Maestre N, Bettaïeb A, Laurent G, Lautier D (2002)
Influence of ceramide metabolism on P-glycoprotein function in immature acute myeloid leukemia KG1a cells
Mol Pharmacol, 62 (2), 304-12
DOI 10.1124/mol.62.2.304, PubMed 12130682
Ringerike T, Blystad FD, Levy FO, Madshus IH, Stang E (2002)
Cholesterol is important in control of EGF receptor kinase activity but EGF receptors are not concentrated in caveolae
J Cell Sci, 115 (Pt 6), 1331-40
PubMed 11884532
Straand J, Myhr K (2002)
[Drug industry dependence]
Tidsskr Nor Laegeforen, 122 (5), 469
PubMed 11961972

Publications 2001

Andersson PL, Berg AH, Bjerselius R, Norrgren L, Olsén H, Olsson PE, Orn S, Tysklind M (2001)
Bioaccumulation of selected PCBs in zebrafish, three-spined stickleback, and arctic char after three different routes of exposure
Arch Environ Contam Toxicol, 40 (4), 519-30
DOI 10.1007/s002440010205, PubMed 11525495
Bach T, Syversveen T, Kvingedal AM, Krobert KA, Brattelid T, Kaumann AJ, Levy FO (2001)
5HT4(a) and 5-HT4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle
Naunyn Schmiedebergs Arch Pharmacol, 363 (2), 146-60
DOI 10.1007/s002100000299, PubMed 11218067
Baekelandt M, Lehne G, Tropé CG, Szántó I, Pfeiffer P, Gustavssson B, Kristensen GB (2001)
Phase I/II trial of the multidrug-resistance modulator valspodar combined with cisplatin and doxorubicin in refractory ovarian cancer
J Clin Oncol, 19 (12), 2983-93
DOI 10.1200/JCO.2001.19.12.2983, PubMed 11408493
Bialer M, Johannessen SI, Kupferberg HJ, Levy RH, Loiseau P, Perucca E (2001)
Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V)
Epilepsy Res, 43 (1), 11-58
DOI 10.1016/s0920-1211(00)00171-6, PubMed 11137386
Bjerselius R, Lundstedt-Enkel K, Olsén H, Mayer I, Dimberg K (2001)
Male goldfish reproductive behaviour and physiology are severely affected by exogenous exposure to 17beta-estradiol
Aquat Toxicol, 53 (2), 139-52
DOI 10.1016/s0166-445x(00)00160-0, PubMed 11311390
Buajordet I, Ebbesen J, Erikssen J, Brørs O, Hilberg T (2001)
Fatal adverse drug events: the paradox of drug treatment
J Intern Med, 250 (4), 327-41
DOI 10.1046/j.1365-2796.2001.00892.x, PubMed 11576320
Ebbesen J, Buajordet I, Erikssen J, Brørs O, Hilberg T, Svaar H, Sandvik L (2001)
Drug-related deaths in a department of internal medicine
Arch Intern Med, 161 (19), 2317-23
DOI 10.1001/archinte.161.19.2317, PubMed 11606147
Johansen PW, Paulssen RH, Bjøro T, Gautvik KM, Gordeladze JO (2001)
Distinct guanine nucleotide binding protein alpha-subunit receptor coupling in GH cell lines: effects of bromocriptine and hormones on effector enzyme modulation
Cell Physiol Biochem, 11 (6), 339-52
DOI 10.1159/000047820, PubMed 11832659
Kajiwara N, Kannan K, Muraoka M, Watanabe M, Takahashi S, Gulland F, Olsen H, Blankenship AL, Jones PD, Tanabe S, Giesy JP (2001)
Organochlorine pesticides, polychlorinated biphenyls, and butyltin compounds in blubber and livers of stranded California sea lions, elephant seals, and harbor seals from coastal California, USA
Arch Environ Contam Toxicol, 41 (1), 90-9
DOI 10.1007/s002440010224, PubMed 11385594
Krobert KA, Bach T, Syversveen T, Kvingedal AM, Levy FO (2001)
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution
Naunyn Schmiedebergs Arch Pharmacol, 363 (6), 620-32
DOI 10.1007/s002100000369, PubMed 11414657
Laupèze B, Amiot L, Bertho N, Grosset JM, Lehne G, Fauchet R, Fardel O (2001)
Differential expression of the efflux pumps P-glycoprotein and multidrug resistance-associated protein in human monocyte-derived dendritic cells
Hum Immunol, 62 (10), 1073-80
DOI 10.1016/s0198-8859(01)00307-x, PubMed 11600213
Laupèze B, Amiot L, Payen L, Drénou B, Grosset JM, Lehne G, Fauchet R, Fardel O (2001)
Multidrug resistance protein (MRP) activity in normal mature leukocytes and CD34-positive hematopoietic cells from peripheral blood
Life Sci, 68 (11), 1323-31
DOI 10.1016/s0024-3205(00)01026-2, PubMed 11233999
Potter H, Wefes IM, Nilsson LN (2001)
The inflammation-induced pathological chaperones ACT and apo-E are necessary catalysts of Alzheimer amyloid formation
Neurobiol Aging, 22 (6), 923-30
DOI 10.1016/s0197-4580(01)00308-6, PubMed 11755000
Sharikabad MN, Ostbye KM, Brørs O (2001)
Increased [Mg2+]o reduces Ca2+ influx and disruption of mitochondrial membrane potential during reoxygenation
Am J Physiol Heart Circ Physiol, 281 (5), H2113-23
DOI 10.1152/ajpheart.2001.281.5.H2113, PubMed 11668073
Sharikabad MN, Ostbye KM, Lyberg T, Brørs O (2001)
Effect of extracellular Mg(2+) on ROS and Ca(2+) accumulation during reoxygenation of rat cardiomyocytes
Am J Physiol Heart Circ Physiol, 280 (1), H344-53
DOI 10.1152/ajpheart.2001.280.1.H344, PubMed 11123250
Skibeli V, Nissen-Lie G, Torjesen P (2001)
Sugar profiling proves that human serum erythropoietin differs from recombinant human erythropoietin
Blood, 98 (13), 3626-34
DOI 10.1182/blood.v98.13.3626, PubMed 11739166
Vang T, Torgersen KM, Sundvold V, Saxena M, Levy FO, Skålhegg BS, Hansson V, Mustelin T, Taskén K (2001)
Activation of the COOH-terminal Src kinase (Csk) by cAMP-dependent protein kinase inhibits signaling through the T cell receptor
J Exp Med, 193 (4), 497-507
DOI 10.1084/jem.193.4.497, PubMed 11181701
Vercoutere W, Winters-Hilt S, Olsen H, Deamer D, Haussler D, Akeson M (2001)
Rapid discrimination among individual DNA hairpin molecules at single-nucleotide resolution using an ion channel
Nat Biotechnol, 19 (3), 248-52
DOI 10.1038/85696, PubMed 11231558
Vinge LE, Øie E, Andersson Y, Grøgaard HK, Andersen G, Attramadal H (2001)
Myocardial distribution and regulation of GRK and beta-arrestin isoforms in congestive heart failure in rats
Am J Physiol Heart Circ Physiol, 281 (6), H2490-9
DOI 10.1152/ajpheart.2001.281.6.H2490, PubMed 11709416
Walsh K, Jaeger T, Gretner H, De Wildt M, Olsen H, Blandy J (2001)
The European Society for Residents in Urology: what have we learnt and where are we going?
BJU Int, 87 (3), 165-7
DOI 10.1046/j.1464-410x.2001.02051.x, PubMed 11167635
Westergren T (2001)
[New preparations against influenza]
Tidsskr Nor Laegeforen, 121 (4), 466-7
PubMed 11255865
Westheim A, Klemetsrud T, Tretli S, Stokke HP, Olsen H (2001)
Blood pressure levels in treated hypertensive patients in general practice in Norway
Blood Press, 10 (1), 37-42
DOI 10.1080/080370501750183372, PubMed 11332332

Publications 2000

Berry D, Tomson T, Johannessen SI (2000)
New antiepileptic drugs
Ann Clin Biochem, 37 ( Pt 4), 551-3
PubMed 10902877
Birkeland KI, Stray-Gundersen J, Hemmersbach P, Hallen J, Haug E, Bahr R (2000)
Effect of rhEPO administration on serum levels of sTfR and cycling performance
Med Sci Sports Exerc, 32 (7), 1238-43
DOI 10.1097/00005768-200007000-00009, PubMed 10912888
Bourdon DM, Camden JM, Landon LA, Levy FO, Turner JT (2000)
Identification of the adenylyl cyclase-activating 5-hydroxytryptamine receptor subtypes expressed in the rat submandibular gland
Br J Pharmacol, 130 (1), 104-8
DOI 10.1038/sj.bjp.0703303, PubMed 10781004
Lehne G, Mørkrid L, den Boer M, Rugstad HE (2000)
Diverse effects of P-glycoprotein inhibitory agents on human leukemia cells expressing the multidrug resistance protein (MRP)
Int J Clin Pharmacol Ther, 38 (4), 187-95
DOI 10.5414/cpp38187, PubMed 10783828
Lieblein G, Francis C, Barth-Eide W, Torjusen H, Solberg S, Salomonsson L, Lund V, Ekblad G, Persson P, Helenius J, Loiva M, Seppanen L, Kahiluoto H, Porter J, Olsen H, Sriskandarajah N, Mikk M, Flora C (2000)
Future education in ecological agriculture and food systems: A student-faculty evaluation and planning process
J. Sustain. Agric., 16 (4), 49-69
Lindberger M, Alenius M, Frisén L, Johannessen SI, Larsson S, Malmgren K, Tomson T (2000)
Gabapentin versus vigabatrin as first add-on for patients with partial seizures that failed to respond to monotherapy: a randomized, double-blind, dose titration study. GREAT Study Investigators Group. Gabapentin in Refractory Epilepsy Add-on Treatment
Epilepsia, 41 (10), 1289-95
DOI 10.1111/j.1528-1157.2000.tb04607.x, PubMed 11051124
Munthe E, Rian E, Holien T, Rasmussen A, Levy FO, Aasheim H (2000)
Ephrin-B2 is a candidate ligand for the Eph receptor, EphB6
FEBS Lett, 466 (1), 169-74
DOI 10.1016/s0014-5793(99)01793-7, PubMed 10648835
Nakken KO, Johannessen SI, Rytter E (2000)
[Adverse effects of antiepileptic agents]
Tidsskr Nor Laegeforen, 120 (26), 3163-5
PubMed 11109365
Sharikabad MN, Hagelin EM, Hagberg IA, Lyberg T, Brørs O (2000)
Effect of calcium on reactive oxygen species in isolated rat cardiomyocytes during hypoxia and reoxygenation
J Mol Cell Cardiol, 32 (3), 441-52
DOI 10.1006/jmcc.1999.1092, PubMed 10731443
Shi Y, Ullrich SJ, Zhang J, Connolly K, Grzegorzewski KJ, Barber MC, Wang W, Wathen K, Hodge V, Fisher CL, Olsen H, Ruben SM, Knyazev I, Cho YH, Kao V, Wilkinson KA, Carrell JA, Ebner R (2000)
A novel cytokine receptor-ligand pair. Identification, molecular characterization, and in vivo immunomodulatory activity
J Biol Chem, 275 (25), 19167-76
DOI 10.1074/jbc.M910228199, PubMed 10749887
Stokke HP, Klemetsrud T, Westheim A, Tretli S, Olsen H (2000)
[Prescription patterns of antihypertensive agents in general practice in 1995]
Tidsskr Nor Laegeforen, 120 (10), 1136-40
PubMed 10863341
Svendsen T, Johannessen SI, Nakken KO (2000)
[Topiramate--a new antiepileptic agents]
Tidsskr Nor Laegeforen, 120 (13), 1536-8
PubMed 10916475
Tomson T, Johannessen SI (2000)
Therapeutic monitoring of the new antiepileptic drugs
Eur J Clin Pharmacol, 55 (10), 697-705
DOI 10.1007/s002280050001, PubMed 10663446