Publications

Publications published since 2000 from OUS - Department of Pharmacology

622 publications found

Publications 2022

1. Akbar R, Bashour H, Rawat P, Robert PA, Smorodina E, Cotet TS, Flem-Karlsen K, Frank R, Mehta BB, Vu MH, Zengin T, Gutierrez-Marcos J, Lund-Johansen F, Andersen JT, Greiff V (2022)
   Progress and challenges for the machine learning-based design of fit-for-purpose monoclonal antibodies
   MAbs, 14 (1), 2008790
   DOI 10.1080/19420862.2021.2008790, PubMed 35293269
2. Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Perucca P, Tomson T, White HS (2022)
   Progress report on new antiepileptic drugs: A summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI): I. Drugs in preclinical and early clinical development
   Epilepsia (in press)
   DOI 10.1111/epi.17373, PubMed 35946083
3. Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Perucca P, Tomson T, White HS (2022)
   Progress report on new antiepileptic drugs: A summary of the Sixteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVI): II. Drugs in more advanced clinical development
   Epilepsia (in press)
   DOI 10.1111/epi.17376, PubMed 35950617
4. Bækken LV, Holden G, Gjelstad A, Lauritzen F (2022)
   Ten years of collecting hematological athlete biological passport samples-perspectives from a National Anti-doping Organization
   Front Sports Act Living, 4, 954479
   DOI 10.3389/fspor.2022.954479, PubMed 35928963
5. Calamera G, Moltzau LR, Levy FO, Andressen KW (2022)
   Phosphodiesterases and Compartmentation of cAMP and cGMP Signaling in Regulation of Cardiac Contractility in Normal and Failing Hearts
   Int J Mol Sci, 23 (4)
   DOI 10.3390/ijms23042145, PubMed 35216259
6. Foss S, Jonsson A, Bottermann M, Watkinson R, Lode HE, McAdam MB, Michaelsen TE, Sandlie I, James LC, Andersen JT (2022)
   Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge
   Sci Immunol, 7 (70), eabj1640
   DOI 10.1126/sciimmunol.abj1640, PubMed 35486676
7. Gjølberg TT, Frick R, Mester S, Foss S, Grevys A, Høydahl LS, Jørstad ØK, Schlothauer T, Sandlie I, Moe MC, Andersen JT (2022)
   Biophysical differences in IgG1 Fc-based therapeutics relate to their cellular handling, interaction with FcRn and plasma half-life
   Commun Biol, 5 (1), 832
   DOI 10.1038/s42003-022-03787-x, PubMed 35982144
8. Hagesæther MM, Torp HA, Ingebrigtsen K, Bjorå CS, von Krogh A, Vevelstad MS (2022)
   Plants – the perfect murder weapon?
   Tidsskr Nor Laegeforen, 142 (6)
   DOI 10.4045/tidsskr.22.0035, PubMed 35383446
9. Halvorsen LV, Bergland OU, Søraas CL, Larstorp ACK, Hjørnholm U, Kjær VN, Kringen MK, Clasen PE, Haldsrud R, Kjeldsen SE, Rostrup M, Fadl Elmula FEM, Opdal MS, Høieggen A (2022)
   Nonadherence by Serum Drug Analyses in Resistant Hypertension: 7-Year Follow-Up of Patients Considered Adherent by Directly Observed Therapy
   J Am Heart Assoc, 11 (18), e025879
   DOI 10.1161/JAHA.121.025879, PubMed 36073648
10. Henning O, Alfstad KÅ, Johannessen Landmark C, Helmstaedter C, Lossius MI, Holth Skogan A (2022)
    Use of screening tools to assess comorbidities and adverse events in patients with epilepsy. A European Reference Network for Rare and Complex Epilepsies (EpiCARE) survey
    Seizure, 101, 237-243 (in press)
    DOI 10.1016/j.seizure.2022.09.008, PubMed 36115293
11. Larsson D, Baftiu A, Johannessen Landmark C, von Euler M, Kumlien E, Åsberg S, Zelano J (2022)
    Association Between Antiseizure Drug Monotherapy and Mortality for Patients With Poststroke Epilepsy
    JAMA Neurol, 79 (2), 169-175
    DOI 10.1001/jamaneurol.2021.4584, PubMed 34902006
12. Lemaitre F, Budde K, Van Gelder T, Bergan S, Lawson R, Noceti O, Venkataramanan R, Elens L, Moes DJAR, Hesselink DA, Pawinski T, Johnson-Davis KL, De Winter BCM, Pattanaik S, Brunet M, Masuda S, Langman LJ (2022)
    Therapeutic drug monitoring and dosage adjustments of immunosuppressive drugs when combined with nirmatrelvir/ritonavir in patients with COVID-19
    Ther Drug Monit (in press)
    DOI 10.1097/FTD.0000000000001014, PubMed 35944126
13. Levay MK, Krobert KA, Vogt A, Ahmad A, Jungmann A, Neuber C, Pasch S, Hansen A, Müller OJ, Lutz S, Wieland T (2022)
    RGS3L allows for an M₂ muscarinic receptor-mediated RhoA-dependent inotropy in cardiomyocytes
    Basic Res Cardiol, 117 (1), 8
    DOI 10.1007/s00395-022-00915-w, PubMed 35230541
14. Manfra O, Calamera G, Froese A, Arunthavarajah D, Surdo NC, Meier S, Melleby AO, Aasrum M, Aronsen JM, Nikolaev VO, Zaccolo M, Moltzau LR, Levy FO, Andressen KW (2022)
    CNP regulates cardiac contractility and increases cGMP near both SERCA and TnI: difference from BNP visualized by targeted cGMP biosensors
    Cardiovasc Res, 118 (6), 1506-1519
    DOI 10.1093/cvr/cvab167, PubMed 33970224
15. Müller LD, Føreid S (2022)
    A comparison of an optimized automated sample preparation of PEth in blood pretreated by freezing versus manual preparation in whole blood, analyzing by UHPLC - MS/MS
    J Pharm Biomed Anal, 212, 114635
    DOI 10.1016/j.jpba.2022.114635, PubMed 35152009
16. Perovic V, Sabol I, Grce M, Inngjerdingen M, Pulanic D, Peric Z, Peczynski C, Polge E, Koenecke C, Dickinson A, Greinix H, Basak G, Penack O, Scherwath A, Barata A, Olivieri A, Lawitschka A, Mensah-Glanowska P, Andrikovics H, Schoemans H, Wolff D (2022)
    Practice patterns in chronic graft-versus-host disease patient management and patient reported outcome measures across the EBMT allogeneic transplantation network
    Bone Marrow Transplant, 57 (9), 1458-1460
    DOI 10.1038/s41409-022-01733-3, PubMed 35690692
17. Pisana A, Wettermark B, Kurdi A, Tubic B, Pontes C, Zara C, Van Ganse E, Petrova G, Mardare I, Fürst J, Roig-Izquierdo M, Melien O, Bonanno PV, Banzi R, Marković-Peković V, Mitkova Z, Godman B (2022)
    Challenges and Opportunities With Routinely Collected Data on the Utilization of Cancer Medicines. Perspectives From Health Authority Personnel Across 18 European Countries
    Front Pharmacol, 13, 873556
    DOI 10.3389/fphar.2022.873556, PubMed 35865969
18. Revdal E, Morken G, Bakken IJ, Bråthen G, Landmark CJ, Brodtkorb E (2022)
    Bidirectionality of antiseizure and antipsychotic treatment: A population-based study
    Epilepsy Behav, 136, 108911 (in press)
    DOI 10.1016/j.yebeh.2022.108911, PubMed 36126553
19. Sand KMK, Gruber MM, Sandlie I, Mathiesen L, Andersen JT, Wadsack C (2022)
    Contribution of the ex vivo placental perfusion model in understanding transplacental immunoglobulin G transfer
    Placenta, 127, 77-87
    DOI 10.1016/j.placenta.2022.07.019, PubMed 35981406
20. Skogestad J, Aronsen JM (2022)
    Regulation of Cardiac Contractility by the Alpha 2 Subunit of the Na⁺/K⁺-ATPase
    Front Physiol, 13, 827334
    DOI 10.3389/fphys.2022.827334, PubMed 35812308
21. Sudworth A, Segers FM, Yilmaz B, Guslund NC, Macpherson AJ, Dissen E, Qiao SW, Inngjerdingen M (2022)
    Innate lymphoid cell characterization in the rat and their correlation to gut commensal microbes
    Eur J Immunol, 52 (5), 717-729
    DOI 10.1002/eji.202149639, PubMed 35099074
22. Svendsen T, Brodtkorb E, Linge HL, Burns ML, Johannessen SI, Nakken KO, Lossius MI, Landmark CJ (2022)
    Efficacy, tolerability and pharmacokinetic variability of brivaracetam in adults with difficult-to-treat epilepsy
    Epilepsy Res, 183, 106946
    DOI 10.1016/j.eplepsyres.2022.106946, PubMed 35609355
23. Sverre E, Peersen K, Kristiansen O, Fagerland MW, Perk J, Husebye E, Vethe NT, Dammen T, Munkhaugen J (2022)
    Tailored clinical management after blinded statin challenge improved the lipid control in coronary patients with self-perceived muscle side effects
    J Intern Med, 291 (6), 891-893
    DOI 10.1111/joim.13454, PubMed 35103360
24. Thorstensen CW, Clasen PE, Rognstad S, Haldsrud R, Føreid S, Helstrøm T, Bergland OU, Halvorsen LV, Aune A, Olsen E, Brobak KM, Høieggen A, Gustavsen I, Larstorp ACK, Søraas CL, Opdal MS (2022)
    Development of UHPLC-MS/MS methods to quantify 25 antihypertensive drugs in serum in a cohort of patients treated for hypertension
    J Pharm Biomed Anal, 219, 114908
    DOI 10.1016/j.jpba.2022.114908, PubMed 35803015
25. Vethe NT, Husebye E, Andersen AM, Bergan S, Kristiansen O, Fagerland MW, Munkhaugen J (2022)
    Monitoring Simvastatin Adherence in Patients With Coronary Heart Disease: A Proof-of-Concept Study Based on Pharmacokinetic Measurements in Blood Plasma
    Ther Drug Monit, 44 (4), 558-567
    DOI 10.1097/FTD.0000000000000992, PubMed 35482468
26. Vevelstad MS, Øiestad ÅML, Johansen U, von Krogh A, Torp HA (2022)
    Yew – a toxic shrub veiled in myth with medical potential
    Tidsskr Nor Laegeforen, 142 (6)
    DOI 10.4045/tidsskr.22.0033, PubMed 35383451
27. Westergren T, Narum S, Klemp M (2022)
    Biases in reporting of adverse effects in clinical trials, and potential impact on safety assessments in systematic reviews and therapy guidelines
    Basic Clin Pharmacol Toxicol (in press)
    DOI 10.1111/bcpt.13791, PubMed 36125975
28. Zakrzewicz A, Würth C, Beckert B, Feldhoff S, Vanderheyden K, Foss S, Andersen JT, Haard H, Verheesen P, Bobkov V, Tikkanen R (2022)
    Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus?
    Cells, 11 (6)
    DOI 10.3390/cells11060942, PubMed 35326398
29. Zakrzewicz A, Würth C, Beckert B, Feldhoff S, Vanderheyden K, Foss S, Andersen JT, Haard H, Verheesen P, Bobkov V, Tikkanen R (2022)
    Correction: Zakrzewicz et al. Stabilization of Keratinocyte Monolayer Integrity in the Presence of Anti-Desmoglein-3 Antibodies through FcRn Blockade with Efgartigimod: Novel Treatment Paradigm for Pemphigus? Cells 2022, 11, 942
    Cells, 11 (10)
    DOI 10.3390/cells11101700, PubMed 35626757
30. Åbjørsbråten KS, Skaaraas GHES, Cunen C, Bjørnstad DM, Binder KMG, Bojarskaite L, Jensen V, Nilsson LNG, Rao SB, Tang W, Hermansen GH, Nagelhus EA, Ottersen OP, Torp R, Enger R (2022)
    Impaired astrocytic Ca²⁺ signaling in awake-behaving Alzheimer's disease transgenic mice
    Elife, 11
    DOI 10.7554/eLife.75055, PubMed 35833623
31. Aarsund M, Segers FM, Wu Y, Inngjerdingen M (2022)
    Comparison of characteristics and tumor targeting properties of extracellular vesicles derived from primary NK cells or NK-cell lines stimulated with IL-15 or IL-12/15/18
    Cancer Immunol Immunother, 71 (9), 2227-2238
    DOI 10.1007/s00262-022-03161-0, PubMed 35119498

Publications 2021

1. Andersen AM, Bergan S, Gedde-Dahl T, Buechner J, Vethe NT (2021)
   Fast and reliable quantification of busulfan in blood plasma using two-channel liquid chromatography tandem mass spectrometry: Validation of assay performance in the presence of drug formulation excipients
   J Pharm Biomed Anal, 203, 114216
   DOI 10.1016/j.jpba.2021.114216, PubMed 34182411
2. Azevedo C, Andersen JT, Traverso G, Sarmento B (2021)
   The potential of porcine ex vivo platform for intestinal permeability screening of FcRn-targeted drugs
   Eur J Pharm Biopharm, 162, 99-104
   DOI 10.1016/j.ejpb.2021.03.009, PubMed 33771621
3. Azevedo C, Pinto S, Benjakul S, Nilsen J, Santos HA, Traverso G, Andersen JT, Sarmento B (2021)
   Prevention of diabetes-associated fibrosis: Strategies in FcRn-targeted nanosystems for oral drug delivery
   Adv Drug Deliv Rev, 175, 113778
   DOI 10.1016/j.addr.2021.04.016, PubMed 33887405
4. Barnes NM, Ahern GP, Becamel C, Bockaert J, Camilleri M, Chaumont-Dubel S, Claeysen S, Cunningham KA, Fone KC, Gershon M, Di Giovanni G, Goodfellow NM, Halberstadt AL, Hartley RM, Hassaine G, Herrick-Davis K, Hovius R, Lacivita E, Lambe EK, Leopoldo M, Levy FO, Lummis SCR, Marin P, Maroteaux L, McCreary AC et al. (2021)
   International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function
   Pharmacol Rev, 73 (1), 310-520
   DOI 10.1124/pr.118.015552, PubMed 33370241
5. Barratt-Due A, Olsen IC, Nezvalova-Henriksen K, Kåsine T, Lund-Johansen F, Hoel H, Holten AR, Tveita A, Mathiessen A, Haugli M, Eiken R, Kildal AB, Berg Å, Johannessen A, Heggelund L, Dahl TB, Skåra KH, Mielnik P, Le LAK, Thoresen L, Ernst G, Hoff DAL, Skudal H, Kittang BR, Olsen RB et al. (2021)
   Evaluation of the Effects of Remdesivir and Hydroxychloroquine on Viral Clearance in COVID-19 : A Randomized Trial
   Ann Intern Med, 174 (9), 1261-1269
   DOI 10.7326/M21-0653, PubMed 34251903
6. Baumgartner T, Carreño M, Rocamora R, Bisulli F, Boni A, Brázdil M, Horak O, Craiu D, Pereira C, Guerrini R, San Antonio-Arce V, Schulze-Bonhage A, Zuberi SM, Hallböök T, Kalviainen R, Lagae L, Nguyen S, Quintas S, Franco A, Cross JH, Walker M, Arzimanoglou A, Rheims S, Granata T, Canafoglia L et al. (2021)
   A survey of the European Reference Network EpiCARE on clinical practice for selected rare epilepsies
   Epilepsia Open, 6 (1), 160-170
   DOI 10.1002/epi4.12459, PubMed 33681659
7. Bergan S, Brunet M, Hesselink DA, Johnson-Davis KL, Kunicki PK, Lemaitre F, Marquet P, Molinaro M, Noceti O, Pattanaik S, Pawinski T, Seger C, Shipkova M, Swen JJ, van Gelder T, Venkataramanan R, Wieland E, Woillard JB, Zwart TC, Barten MJ, Budde K, Dieterlen MT, Elens L, Haufroid V, Masuda S et al. (2021)
   Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology
   Ther Drug Monit, 43 (2), 150-200
   DOI 10.1097/FTD.0000000000000871, PubMed 33711005
8. Bergland OU, Halvorsen LV, Søraas CL, Hjørnholm U, Kjær VN, Rognstad S, Brobak KM, Aune A, Olsen E, Fauchald YM, Heimark S, Thorstensen CW, Liestøl K, Solbu MD, Gerdts E, Mo R, Rostrup M, Kjeldsen SE, Høieggen A, Opdal MS, Larstorp ACK, Fadl Elmula FEM (2021)
   Detection of Nonadherence to Antihypertensive Treatment by Measurements of Serum Drug Concentrations
   Hypertension, 78 (3), 617-628
   DOI 10.1161/HYPERTENSIONAHA.121.17514, PubMed 34275336
9. Bjørnebekk A, Kaufmann T, Hauger LE, Klonteig S, Hullstein IR, Westlye LT (2021)
   Long-term Anabolic-Androgenic Steroid Use Is Associated With Deviant Brain Aging
   Biol Psychiatry Cogn Neurosci Neuroimaging, 6 (5), 579-589
   DOI 10.1016/j.bpsc.2021.01.001, PubMed 33811018
10. Brede C, Vethe NT, Skadberg Ø (2021)
    The Question of Accuracy Versus Interlaboratory Agreement for Monitoring the Immunosuppressants Everolimus and Sirolimus
    Ther Drug Monit, 43 (3), 444-446
    DOI 10.1097/FTD.0000000000000892, PubMed 33840796
11. Carlson CR, Aronsen JM, Bergan-Dahl A, Moutty MC, Lunde M, Lunde PK, Jarstadmarken H, Wanichawan P, Pereira L, Kolstad TRS, Dalhus B, Subramanian H, Hille S, Christensen G, Müller OJ, Nikolaev V, Bers DM, Sjaastad I, Shen X, Louch WE, Klussmann E, Sejersted OM (2021)
    AKAP18δ Anchors and Regulates CaMKII Activity at Phospholamban-SERCA2 and RYR
    Circ Res, 130 (1), 27-44
    DOI 10.1161/CIRCRESAHA.120.317976, PubMed 34814703
12. Christopoulos PF, Gjølberg TT, Krüger S, Haraldsen G, Andersen JT, Sundlisæter E (2021)
    Targeting the Notch Signaling Pathway in Chronic Inflammatory Diseases
    Front Immunol, 12, 668207
    DOI 10.3389/fimmu.2021.668207, PubMed 33912195
13. Danielsen TK, Sadredini M, Manotheepan R, Aronsen JM, Frisk M, Hansen MH, Andressen KW, Hougen K, Levy FO, Louch WE, Sejersted OM, Sjaastad I, Stokke MK (2021)
    Exercise Training Stabilizes RyR2-Dependent Ca²⁺ Release in Post-infarction Heart Failure
    Front Cardiovasc Med, 7, 623922
    DOI 10.3389/fcvm.2020.623922, PubMed 33569394
14. Equey T, Sletten C, Dehnes Y, D'Onofrio G, Brugnara C, Baume N, Aikin R (2021)
    Standardization of reticulocyte counts in the athlete biological passport: A practical update
    Int J Lab Hematol, 44 (1), 112-117
    DOI 10.1111/ijlh.13732, PubMed 34709714
15. Heldal K, Åsberg A, Abedini S, Jenssen TG, Reisæter AV, Bergan S, Hartmann A (2021)
    Estimated glomerular filtration rate as a measurement of kidney function
    Tidsskr Nor Laegeforen, 141 (1)
    DOI 10.4045/tidsskr.21.0501, PubMed 35026092
16. Høydahl LS, Frigstad T, Rasmussen IB, Øynebråten I, Schjetne KW, Andersen JT, Michaelsen TE, Lunde E, Bogen B, Sandlie I (2021)
    Antibody-mediated delivery of T-cell epitopes to antigen-presenting cells induce strong CD4 and CD8 T-cell responses
    Vaccine, 39 (11), 1583-1592
    DOI 10.1016/j.vaccine.2021.02.012, PubMed 33612340
17. Johannessen Landmark C, Potschka H, Auvin S, Wilmshurst JM, Johannessen SI, Kasteleijn-Nolst Trenité D, Wirrell EC (2021)
    The role of new medical treatments for the management of developmental and epileptic encephalopathies: Novel concepts and results
    Epilepsia, 62 (4), 857-873
    DOI 10.1111/epi.16849, PubMed 33638459
18. Jorstad OK, Sivertsen MS, Andersen JT, Moe MC (2021)
    Can the ampoules of covid-19 vaccine be used better?
    Tidsskr. Nor. Laegeforen., 141 (2), 110
19. Kindem IA, Bjerre A, Åsberg A, Midtvedt K, Bergan S, Vethe NT (2021)
    Tacrolimus Measured in Capillary Volumetric Microsamples in Pediatric Patients-A Cross-Validation Study
    Ther Drug Monit, 43 (3), 371-375
    DOI 10.1097/FTD.0000000000000873, PubMed 33596033
20. Klæstad E, Sawicka JE, Engstrøm MJ, Ytterhus B, Valla M, Bofin AM (2021)
    ZNF703 gene copy number and protein expression in breast cancer; associations with proliferation, prognosis and luminal subtypes
    Breast Cancer Res Treat, 186 (1), 65-77
    DOI 10.1007/s10549-020-06035-0, PubMed 33389351
21. Kristiansen O, Sverre E, Peersen K, Fagerland MW, Gjertsen E, Gullestad L, Perk J, Dammen T, Husebye E, Vethe NT, Munkhaugen J (2021)
    The relationship between directly measured statin adherence, self-reported adherence measures and cholesterol levels in patients with coronary heart disease
    Atherosclerosis, 336, 23-29
    DOI 10.1016/j.atherosclerosis.2021.09.020, PubMed 34610521
22. Kristiansen O, Vethe NT, Peersen K, Wang Fagerland M, Sverre E, Prunés Jensen E, Lindberg M, Gjertsen E, Gullestad L, Perk J, Dammen T, Bergan S, Husebye E, Otterstad JE, Munkhaugen J (2021)
    Effect of atorvastatin on muscle symptoms in coronary heart disease patients with self-perceived statin muscle side effects: a randomized, double-blinded crossover trial
    Eur Heart J Cardiovasc Pharmacother, 7 (6), 507-516
    DOI 10.1093/ehjcvp/pvaa076, PubMed 32609361
23. König M, Lorentzen ÅR, Torgauten HM, Tran TT, Schikora-Rustad S, Vaage EB, Mygland Å, Wergeland S, Aarseth J, Aaberge IAS, Torkildsen Ø, Holmøy T, Berge T, Myhr KM, Harbo HF, Andersen JT, Munthe LA, Søraas A, Celius EG, Vaage JT, Lund-Johansen F, Nygaard GO (2021)
    Humoral immunity to SARS-CoV-2 mRNA vaccination in multiple sclerosis: the relevance of time since last rituximab infusion and first experience from sporadic revaccinations
    J Neurol Neurosurg Psychiatry
    DOI 10.1136/jnnp-2021-327612, PubMed 34670844
24. Landmark CJ, Rektorli L, Burns ML, Revdal E, Johannessen SI, Brodtkorb E (2021)
    Pharmacokinetic data on brivaracetam, lacosamide and perampanel during pregnancy and lactation
    Epileptic Disord, 23 (2), 426-431
    DOI 10.1684/epd.2021.1273, PubMed 33935028
25. Lao YE, Vartdal T, Froeyshov S, Latimer B, Kvaerner C, Mataric M, Holm P, Foreid S, Jacobsen D, McMartin K, Hovda KE (2021)
    Fomepizole dosing during continuous renal replacement therapy - an observational study
    Clin Toxicol (Phila), 60 (4), 451-457
    DOI 10.1080/15563650.2021.1980581, PubMed 34585641
26. Lombardi S, Aaen KH, Nilsen J, Ferrarese M, Gjølberg TT, Bernardi F, Pinotti M, Andersen JT, Branchini A (2021)
    Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity
    Br J Haematol, 194 (2), 453-462
    DOI 10.1111/bjh.17559, PubMed 34109608
27. Lossius IMB, Svendsen T, Sødal HF, Kjeldstadli K, Lossius MI, Nakken KO, Johannessen Landmark C (2021)
    Effect and tolerability of perampanel in patients with drug-resistant epilepsy
    Epilepsy Behav, 119, 107965
    DOI 10.1016/j.yebeh.2021.107965, PubMed 33940525
28. Midtlyng L, Høiseth G, Luytkis H, Kristoffersen L, Le Nygaard I, Strand MC, Arnestad M, Vevelstad M (2021)
    Relationship between betahydroxybutyrate (BHB) and acetone concentrations in postmortem blood and cause of death
    Forensic Sci Int, 321, 110726
    DOI 10.1016/j.forsciint.2021.110726, PubMed 33631622
29. Mochol M, Whatmore P, Taubøll E, Landmark CJ, Ropstad E, Svalheim S, Fraser TWK (2021)
    Lamotrigine effects on immune gene expression in larval zebrafish
    Epilepsy Res, 178, 106823
    DOI 10.1016/j.eplepsyres.2021.106823, PubMed 34844088
30. Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
    Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus and hypertension
    Blood Press, 30 (2), 82-89
    DOI 10.1080/08037051.2020.1855968, PubMed 33403886
31. Olsen E, Holzhauer B, Julius S, Kjeldsen SE, Larstorp ACK, Mancia G, Mehlum MH, Mo R, Rostrup M, Søraas CL, Zappe D, Weber MA (2021)
    Cardiovascular outcomes at recommended blood pressure targets in middle-aged and elderly patients with type 2 diabetes mellitus compared to all middle-aged and elderly hypertensive study patients with high cardiovascular risk
    Blood Press, 30 (2), 90-97
    DOI 10.1080/08037051.2020.1856642, PubMed 33403890
32. Pagnon de la Vega M, Giedraitis V, Michno W, Kilander L, Güner G, Zielinski M, Löwenmark M, Brundin R, Danfors T, Söderberg L, Alafuzoff I, Nilsson LNG, Erlandsson A, Willbold D, Müller SA, Schröder GF, Hanrieder J, Lichtenthaler SF, Lannfelt L, Sehlin D, Ingelsson M (2021)
    The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation
    Sci Transl Med, 13 (606)
    DOI 10.1126/scitranslmed.abc6184, PubMed 34380771
33. Peersen K, Munkhaugen J, Sverre E, Kristiansen O, Fagerland M, Vethe NT, Perk J, Husebye E, Dammen T (2021)
    Clinical and psychological factors in coronary heart disease patients with statin associated muscle side-effects
    BMC Cardiovasc Disord, 21 (1), 596
    DOI 10.1186/s12872-021-02422-7, PubMed 34915854
34. Quiles-Jiménez A, Gregersen I, Segers FM, Skarpengland T, Kroustallaki P, Yang K, Kong XY, Lauritzen KH, Olsen MB, Karlsen TR, Nyman TA, Sagen EL, Bjerkeli V, Suganthan R, Nygård S, Scheffler K, Prins J, Van der Veer E, Øgaard JD, Fløisand Y, Jørgensen HF, Holven KB, Biessen EA, Nilsen H, Dahl TB et al. (2021)
    DNA glycosylase Neil3 regulates vascular smooth muscle cell biology during atherosclerosis development
    Atherosclerosis, 324, 123-132
    DOI 10.1016/j.atherosclerosis.2021.02.023, PubMed 33714552
35. Reiter L, Stenberg-Nilsen H, Økland HG (2021)
    Use of anticholinergic drugs in older patients
    Tidsskr Nor Laegeforen, 141 (6)
    DOI 10.4045/tidsskr.20.0775, PubMed 33876622
36. Robertsen I, Åsberg A, Jenssen TG, Gence B, Tore Vethe N, Midtvedt K, Svensson MHS, Eide IA (2021)
    Increased systemic exposure of once-daily tacrolimus in renal transplant recipients on marine omega-3 fatty acid supplementation
    Transpl Int, 34 (7), 1322-1324
    DOI 10.1111/tri.13917, PubMed 33991364
37. Rognstad S, Søraas CL, Bergland OU, Høieggen A, Strømmen M, Helland A, Opdal MS (2021)
    Establishing Serum Reference Ranges for Antihypertensive Drugs
    Ther Drug Monit, 43 (1), 116-125
    DOI 10.1097/FTD.0000000000000806, PubMed 32881780
38. Sivertsen MS, Lode HE, Gjølberg TT, Petrovski G, Andersen JT, Jørstad ØK, Moe MC (2021)
    Cluster of symptomatic silicone oil droplets following intravitreal injections: a 1-year observational study
    BMJ Open Ophthalmol, 6 (1), e000764
    DOI 10.1136/bmjophth-2021-000764, PubMed 34485702
39. Skauby RH, Bergan S, Andersen AM, Vethe NT, Christensen H (2021)
    In vitro assessments predict that CYP3A4 contributes to a greater extent than CYP3A5 to prednisolone clearance
    Basic Clin Pharmacol Toxicol, 129 (6), 427-436
    DOI 10.1111/bcpt.13645, PubMed 34396687
40. Skauby RH, Gustavsen MT, Andersen AM, Bjerre A, Åsberg A, Midtvedt K, Vethe NT, Bergan S (2021)
    Prednisolone and Prednisone Pharmacokinetics in Adult Renal Transplant Recipients
    Ther Drug Monit, 43 (2), 247-255
    DOI 10.1097/FTD.0000000000000835, PubMed 33181621
41. Solheim SA, Levernaes MCS, Mørkeberg J, Juul A, Upners EN, Nordsborg NB, Dehnes Y (2021)
    Stability and detectability of testosterone esters in dried blood spots after intramuscular injections
    Drug Test Anal
    DOI 10.1002/dta.3030, PubMed 33733610
42. Solheim SA, Ringsted TK, Nordsborg NB, Dehnes Y, Levernaes MCS, Mørkeberg J (2021)
    No pain, just gain: Painless, easy, and fast dried blood spot collection from fingertip and upper arm in doping control
    Drug Test Anal, 13 (10), 1783-1790
    DOI 10.1002/dta.3135, PubMed 34346172
43. Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2021)
    Correction to: Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of highgrade pseudomyxoma peritonei
    Clin Exp Metastasis, 38 (2), 253
    DOI 10.1007/s10585-021-10084-0, PubMed 33649933
44. Torp HA, Skurtveit S, Skaga NO, Gustavsen I, Gran JM, Rosseland LA (2021)
    Pre-injury dispensing of psychoactive prescription drugs in a ten years trauma population: a retrospective registry analysis
    Scand J Trauma Resusc Emerg Med, 29 (1), 125
    DOI 10.1186/s13049-021-00939-6, PubMed 34454541
45. Tuv SS, Bergh MS, Andersen JM, Steinsland S, Vindenes V, Baumann MH, Huestis MA, Bogen IL (2021)
    Comparative Neuropharmacology and Pharmacokinetics of Methamphetamine and Its Thiophene Analog Methiopropamine in Rodents
    Int J Mol Sci, 22 (21)
    DOI 10.3390/ijms222112002, PubMed 34769427
46. Wanichawan P, Skogestad J, Lunde M, Støle TP, Stensland M, Nyman TA, Sjaastad I, Sejersted OM, Aronsen JM, Carlson CR (2021)
    Design of a Proteolytically Stable Sodium-Calcium Exchanger 1 Activator Peptide for In Vivo Studies
    Front Pharmacol, 12, 638646
    DOI 10.3389/fphar.2021.638646, PubMed 34163352
47. Wong SH, Marquet P, Cattaneo D, Svinarov D, Bergan S, Walson P, Vinks AA, Shipkova M (2021)
    Therapeutic Drug Monitoring in the Era of Precision Medicine: Achievements, Gaps, and Perspectives-An Interview in Honor of Professor Charles Pippenger
    Ther Drug Monit, 43 (6), 719-727
    DOI 10.1097/FTD.0000000000000932, PubMed 34654029

Publications 2020

1. Amrutkar M, Vethe NT, Verbeke CS, Aasrum M, Finstadsveen AV, Sántha P, Gladhaug IP (2020)
   Differential Gemcitabine Sensitivity in Primary Human Pancreatic Cancer Cells and Paired Stellate Cells Is Driven by Heterogenous Drug Uptake and Processing
   Cancers (Basel), 12 (12)
   DOI 10.3390/cancers12123628, PubMed 33287390
2. Arzimanoglou A, Brandl U, Cross JH, Gil-Nagel A, Lagae L, Landmark CJ, Specchio N, Nabbout R, Thiele EA, Gubbay O, The Cannabinoids International Experts Panel, Collaborators (2020)
   Epilepsy and cannabidiol: a guide to treatment
   Epileptic Disord, 22 (1), 1-14
   DOI 10.1684/epd.2020.1141, PubMed 32096470
3. Azevedo C, Nilsen J, Grevys A, Nunes R, Andersen JT, Sarmento B (2020)
   Engineered albumin-functionalized nanoparticles for improved FcRn binding enhance oral delivery of insulin
   J Control Release, 327, 161-173
   DOI 10.1016/j.jconrel.2020.08.005, PubMed 32771477
4. Bejder J, Breenfeldt Andersen A, Bonne TC, Piil JF, Hagen LCH, Dehnes Y, Eibye KH, Nybo L, Nordsborg NB (2020)
   Tramadol Does Not Improve Performance or Impair Motor Function in Trained Cyclists
   Med Sci Sports Exerc, 52 (5), 1169-1175
   DOI 10.1249/MSS.0000000000002217, PubMed 31809408
5. Bern M, Nilsen J, Ferrarese M, Sand KMK, Gjølberg TT, Lode HE, Davidson RJ, Camire RM, Bækkevold ES, Foss S, Grevys A, Dalhus B, Wilson J, Høydahl LS, Christianson GJ, Roopenian DC, Schlothauer T, Michaelsen TE, Moe MC, Lombardi S, Pinotti M, Sandlie I, Branchini A, Andersen JT (2020)
   An engineered human albumin enhances half-life and transmucosal delivery when fused to protein-based biologics
   Sci Transl Med, 12 (565)
   DOI 10.1126/scitranslmed.abb0580, PubMed 33055243
6. Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Perucca P, Tomson T, White HS (2020)
   Progress report on new antiepileptic drugs: A summary of the Fifteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XV). II. Drugs in more advanced clinical development
   Epilepsia, 61 (11), 2365-2385
   DOI 10.1111/epi.16726, PubMed 33165915
7. Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Perucca P, Tomson T, White HS (2020)
   Progress report on new antiepileptic drugs: A summary of the Fifteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XV). I. Drugs in preclinical and early clinical development
   Epilepsia, 61 (11), 2340-2364
   DOI 10.1111/epi.16725, PubMed 33190243
8. Caddy SL, Vaysburd M, Papa G, Wing M, O'Connell K, Stoycheva D, Foss S, Terje Andersen J, Oxenius A, James LC (2020)
   Viral nucleoprotein antibodies activate TRIM21 and induce T cell immunity
   EMBO J, 40 (5), e106228
   DOI 10.15252/embj.2020106228, PubMed 33258165
9. Caddy SL, Vaysburd M, Wing M, Foss S, Andersen JT, O'Connell K, Mayes K, Higginson K, Iturriza-Gómara M, Desselberger U, James LC (2020)
   Intracellular neutralisation of rotavirus by VP6-specific IgG
   PLoS Pathog, 16 (8), e1008732
   DOI 10.1371/journal.ppat.1008732, PubMed 32750093
10. Crossland RE, Perutelli F, Bogunia-Kubik K, Mooney N, Milutin Gašperov N, Pučić-Baković M, Greinix H, Weber D, Holler E, Pulanić D, Wolff D, Dickinson AM, Inngjerdingen M, Grce M (2020)
    Potential Novel Biomarkers in Chronic Graft-Versus-Host Disease
    Front Immunol, 11, 602547
    DOI 10.3389/fimmu.2020.602547, PubMed 33424849
11. Edwin TH, Henjum K, Nilsson LNG, Watne LO, Persson K, Eldholm RS, Saltvedt I, Halaas NB, Selbæk G, Engedal K, Strand BH, Knapskog AB (2020)
    A high cerebrospinal fluid soluble TREM2 level is associated with slow clinical progression of Alzheimer's disease
    Alzheimers Dement (Amst), 12 (1), e12128
    DOI 10.1002/dad2.12128, PubMed 33313376
12. Egeland EJ, Witczak BJ, Zaré HK, Christensen H, Åsberg A, Robertsen I (2020)
    Chronic Inhibition of CYP3A is Temporarily Reduced by Each Hemodialysis Session in Patients With End-Stage Renal Disease
    Clin Pharmacol Ther, 108 (4), 866-873
    DOI 10.1002/cpt.1875, PubMed 32356565
13. Elens L, Langman LJ, Hesselink DA, Bergan S, Moes DJAR, Molinaro M, Venkataramanan R, Lemaitre F (2020)
    Pharmacologic Treatment of Transplant Recipients Infected With SARS-CoV-2: Considerations Regarding Therapeutic Drug Monitoring and Drug-Drug Interactions
    Ther Drug Monit, 42 (3), 360-368
    DOI 10.1097/FTD.0000000000000761, PubMed 32304488
14. Farcas M, Inngjerdingen M (2020)
    Natural killer cell-derived extracellular vesicles in cancer therapy
    Scand J Immunol, 92 (4), e12938
    DOI 10.1111/sji.12938, PubMed 32697853
15. Franco V, Gatti G, Mazzucchelli I, Marchiselli R, Fattore C, Rota P, Galimberti CA, Capovilla G, Beccaria F, De Giorgis V, Johannessen Landmark C, Perucca E (2020)
    Relationship between saliva and plasma rufinamide concentrations in patients with epilepsy
    Epilepsia, 61 (7), e79-e84
    DOI 10.1111/epi.16584, PubMed 32562438
16. Gustavsen MT, Midtvedt K, Robertsen I, Woillard JB, Debord J, Klaasen RA, Vethe NT, Bergan S, Åsberg A (2020)
    Fasting Status and Circadian Variation Must be Considered When Performing AUC-based Therapeutic Drug Monitoring of Tacrolimus in Renal Transplant Recipients
    Clin Transl Sci, 13 (6), 1327-1335
    DOI 10.1111/cts.12833, PubMed 32652886
17. Gustavsen MT, Midtvedt K, Vethe NT, Robertsen I, Bergan S, Åsberg A (2020)
    Tacrolimus Area Under the Concentration Versus Time Curve Monitoring, Using Home-Based Volumetric Absorptive Capillary Microsampling
    Ther Drug Monit, 42 (3), 407-414
    DOI 10.1097/FTD.0000000000000697, PubMed 31479042
18. Halaas NB, Henjum K, Blennow K, Dakhil S, Idland AV, Nilsson LN, Sederevicius D, Vidal-Piñeiro D, Walhovd KB, Wyller TB, Zetterberg H, Watne LO, Fjell AM (2020)
    CSF sTREM2 and Tau Work Together in Predicting Increased Temporal Lobe Atrophy in Older Adults
    Cereb Cortex, 30 (4), 2295-2306
    DOI 10.1093/cercor/bhz240, PubMed 31812991
19. Heger K, Lund C, Larsen Burns M, Bjørnvold M, Sætre E, Johannessen SI, Johannessen Landmark C (2020)
    A retrospective review of changes and challenges in the use of antiseizure medicines in Dravet syndrome in Norway
    Epilepsia Open, 5 (3), 432-441
    DOI 10.1002/epi4.12413, PubMed 32913951
20. Hemmersbach P (2020)
    Mats Garle
    Drug Test Anal, 12 (11-12), 1543
    DOI 10.1002/dta.2922, PubMed 33006237
21. Henjum K, Årskog V, Jendresen CB, Fladby T, Torp R, Nilsson LNG (2020)
    Analyzing microglial-associated Aβ in Alzheimer's disease transgenic mice with a novel mid-domain Aβ-antibody
    Sci Rep, 10 (1), 10590
    DOI 10.1038/s41598-020-67419-2, PubMed 32601313
22. Holter JC, Pischke SE, de Boer E, Lind A, Jenum S, Holten AR, Tonby K, Barratt-Due A, Sokolova M, Schjalm C, Chaban V, Kolderup A, Tran T, Tollefsrud Gjølberg T, Skeie LG, Hesstvedt L, Ormåsen V, Fevang B, Austad C, Müller KE, Fladeby C, Holberg-Petersen M, Halvorsen B, Müller F, Aukrust P et al. (2020)
    Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients
    Proc Natl Acad Sci U S A, 117 (40), 25018-25025
    DOI 10.1073/pnas.2010540117, PubMed 32943538
23. Hubbard JJ, Pyzik M, Rath T, Kozicky LK, Sand KMK, Gandhi AK, Grevys A, Foss S, Menzies SC, Glickman JN, Fiebiger E, Roopenian DC, Sandlie I, Andersen JT, Sly LM, Baker K, Blumberg RS (2020)
    FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity
    J Exp Med, 217 (10)
    DOI 10.1084/jem.20200359, PubMed 32658257
24. Jang W, Adams CE, Liu H, Zhang C, Levy FO, Andressen KW, Lambert NA (2020)
    An inactive receptor-G protein complex maintains the dynamic range of agonist-induced signaling
    Proc Natl Acad Sci U S A, 117 (48), 30755-30762
    DOI 10.1073/pnas.2010801117, PubMed 33199589
25. Jessen S, Becker V, Rzeppa S, Backer V, Bengtsen KH, Hullstein I, Dehnes Y, Hostrup M (2020)
    Pharmacokinetics of salmeterol and its main metabolite α-hydroxysalmeterol after acute and chronic dry powder inhalation in exercising endurance-trained men: Implications for doping control
    Drug Test Anal, 13 (4), 747-761
    DOI 10.1002/dta.2978, PubMed 33210444
26. Johannessen Landmark C, Heger K, Lund C, Burns ML, Bjørnvold M, Sætre E, Johannessen SI (2020)
    Pharmacokinetic Variability During Long-Term Therapeutic Drug Monitoring of Valproate, Clobazam, and Levetiracetam in Patients With Dravet Syndrome
    Ther Drug Monit, 42 (5), 744-753
    DOI 10.1097/FTD.0000000000000781, PubMed 32558674
27. Johannessen Landmark C, Johannessen SI, Patsalos PN (2020)
    Therapeutic drug monitoring of antiepileptic drugs: current status and future prospects
    Expert Opin Drug Metab Toxicol, 16 (3), 227-238
    DOI 10.1080/17425255.2020.1724956, PubMed 32054370
28. Klaasen RA, Bergan S, Bremer S, Hole K, Nordahl CB, Andersen AM, Midtvedt K, Skauby MH, Vethe NT (2020)
    Pharmacodynamic assessment of mycophenolic acid in resting and activated target cell population during the first year after renal transplantation
    Br J Clin Pharmacol, 86 (6), 1100-1112
    DOI 10.1111/bcp.14218, PubMed 31925806
29. Knapskog AB, Henjum K, Idland AV, Eldholm RS, Persson K, Saltvedt I, Watne LO, Engedal K, Nilsson LNG (2020)
    Cerebrospinal fluid sTREM2 in Alzheimer's disease: comparisons between clinical presentation and AT classification
    Sci Rep, 10 (1), 15886
    DOI 10.1038/s41598-020-72878-8, PubMed 32985583
30. Kvamsøe MM, Hansen KR, Skadberg Ø, Vethe NT, Brede C (2020)
    Salting Out-Assisted Liquid-Liquid Extraction for Liquid Chromatography-Tandem Mass Spectrometry Measurement of Tacrolimus, Sirolimus, Everolimus, and Cyclosporine a in Whole Blood
    Ther Drug Monit, 42 (5), 695-701
    DOI 10.1097/FTD.0000000000000794, PubMed 32701594
31. Lang GP, Ndongson-Dongmo B, Lajqi T, Brodhun M, Han Y, Wetzker R, Frasch MG, Bauer R (2020)
    Impact of ambient temperature on inflammation-induced encephalopathy in endotoxemic mice-role of phosphoinositide 3-kinase gamma
    J Neuroinflammation, 17 (1), 292
    DOI 10.1186/s12974-020-01954-7, PubMed 33028343
32. Lau C, McAdam MB, Bergseth G, Grevys A, Bruun JA, Ludviksen JK, Fure H, Espevik T, Moen A, Andersen JT, Mollnes TE (2020)
    NHDL, a recombinant V_L/V_H hybrid antibody control for IgG2/4 antibodies
    MAbs, 12 (1), 1686319
    DOI 10.1080/19420862.2019.1686319, PubMed 31671278
33. Lemaitre F, Vethe NT, D'Avolio A, Tron C, Robertsen I, De Winter B, Denicolo A, Koch BCP, Venkataramanan R, Van Gelder T, Brunet M, Bergan S, Hesselink DA, Wallemacq P (2020)
    Measuring Intracellular Concentrations of Calcineurin Inhibitors: Expert Consensus from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Expert Panel
    Ther Drug Monit, 42 (5), 665-670
    DOI 10.1097/FTD.0000000000000780, PubMed 32520841
34. Mullen J, Baekken LV, Törmäkangas T, Ekström L, Ericsson M, Hullstein IR, Schulze JJ (2020)
    Inter-individual variation of the urinary steroid profiles in Swedish and Norwegian athletes
    Drug Test Anal, 12 (6), 720-730
    DOI 10.1002/dta.2778, PubMed 32052600
35. Neerland BE, Halaas NB, Idland AV, Henjum K, Blennow K, Zetterberg H, Watne LO (2020)
    Fatty Acid-Binding Protein 3 in Cerebrospinal Fluid of Hip Fracture Patients with Delirium
    J Alzheimers Dis, 77 (1), 183-190
    DOI 10.3233/JAD-200364, PubMed 32804136
36. Saidu NEB, Bonini C, Dickinson A, Grce M, Inngjerdingen M, Koehl U, Toubert A, Zeiser R, Galimberti S (2020)
    New Approaches for the Treatment of Chronic Graft-Versus-Host Disease: Current Status and Future Directions
    Front Immunol, 11, 578314
    DOI 10.3389/fimmu.2020.578314, PubMed 33162993
37. Schrottmaier WC, Salzmann M, Badrnya S, Mussbacher M, Kral-Pointner JB, Morava S, Pirabe A, Brunnthaler L, Yaiw KC, Heber UM, Pereyra D, Andersen JT, Bergthaler A, Söderberg-Nauclér C, Karlsson MCI, Assinger A, Forsell MNE (2020)
    Platelets mediate serological memory to neutralize viruses in vitro and in vivo
    Blood Adv, 4 (16), 3971-3976
    DOI 10.1182/bloodadvances.2020001786, PubMed 32841338
38. Solheim SA, Jessen S, Mørkeberg J, Thevis M, Dehnes Y, Eibye K, Hostrup M, Nordsborg NB (2020)
    Single-dose administration of clenbuterol is detectable in dried blood spots
    Drug Test Anal, 12 (9), 1366-1372
    DOI 10.1002/dta.2872, PubMed 32495983
39. Solheim SA, Mørkeberg J, Dehnes Y, Hullstein I, Juul A, Upners EN, Nordsborg NB (2020)
    Changes in blood parameters after intramuscular testosterone ester injections - Implications for anti-doping
    Drug Test Anal, 12 (8), 1019-1030
    DOI 10.1002/dta.2803, PubMed 32307878
40. Solheim SA, Mørkeberg J, Juul A, Freiesleben SY, Upners EN, Dehnes Y, Nordsborg NB (2020)
    An Intramuscular Injection of Mixed Testosterone Esters Does Not Acutely Enhance Strength and Power in Recreationally Active Young Men
    Front Physiol, 11, 563620
    DOI 10.3389/fphys.2020.563620, PubMed 33071818
41. Svendsen T, Brodtkorb E, Baftiu A, Lossius MI, Nakken KO, Johannessen SI, Johannessen Landmark C (2020)
    Clinical experience combined with therapeutic drug monitoring of lacosamide
    Acta Neurol Scand, 141 (4), 279-286
    DOI 10.1111/ane.13206, PubMed 31853958
42. Torp HA, Nystoyl B (2020)
    Neutropenia in treatment with antipsychotics
    Tidsskr. Nor. Laegeforen., 140 (8), 793-795
43. Tuv SS, Bjanes TK, Nordal K (2020)
    Genotyping may cause fewer side effects with cancer treatment
    Tidsskr. Nor. Laegeforen., 140 (15), 1530
44. Westergren T, Narum S, Klemp M (2020)
    Adverse effects information in clinical guidelines on pharmacological treatment of depression in children and adolescents: a systematic review
    BMJ Open, 10 (7), e036412
    DOI 10.1136/bmjopen-2019-036412, PubMed 32690742

Publications 2019

1. Alvestad S, Bjørnvold M, Molteberg E, Lossius M, Landmark CJ (2019)
   Continued importance of valproate for women with generalised epilepsy
   Tidsskr Nor Laegeforen, 139 (7)
   DOI 10.4045/tidsskr.19.0220, PubMed 30969058
2. Andreassen BK, Støer NC, Martinsen JI, Ursin G, Weiderpass E, Thoresen GH, Debernard KB, Karlstad Ø, Pottegard A, Friis S (2019)
   Identification of potential carcinogenic and chemopreventive effects of prescription drugs: a protocol for a Norwegian registry-based study
   BMJ Open, 9 (4), e028504
   DOI 10.1136/bmjopen-2018-028504, PubMed 30962244
3. Baftiu A, Lima MH, Svendsen K, Larsson PG, Johannessen SI, Landmark CJ (2019)
   Safety aspects of antiepileptic drugs-a population-based study of adverse effects relative to changes in utilisation
   Eur J Clin Pharmacol, 75 (8), 1153-1160
   DOI 10.1007/s00228-019-02678-1, PubMed 31001654
4. Bergström M, Müller M, Karlsson M, Scholz H, Vethe NT, Korsgren O (2019)
   Comparing the Effects of the mTOR Inhibitors Azithromycin and Rapamycin on In Vitro Expanded Regulatory T Cells
   Cell Transplant, 28 (12), 1603-1613
   DOI 10.1177/0963689719872488, PubMed 31512504
5. Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS (2019)
   A summary of data presented at the XIV conference on new antiepileptic drug and devices (EILAT XIV)
   Epilepsy Res, 153, 66-67
   DOI 10.1016/j.eplepsyres.2019.03.002, PubMed 30910314
6. Blom KB, Bergo KK, Espe EKS, Rosseland V, Grøtta OJ, Mjøen G, Åsberg A, Bergan S, Sanner H, Bergersen TK, Bjørnerheim R, Skauby M, Seljeflot I, Waldum-Grevbo B, Dahle DO, Sjaastad I, Birkeland JA (2019)
   Cardiovascular rEmodelling in living kidNey donorS with reduced glomerular filtration rate: rationale and design of the CENS study
   Blood Press, 29 (2), 123-134
   DOI 10.1080/08037051.2019.1684817, PubMed 31718316
7. Bottermann M, Foss S, Caddy SL, Clift D, van Tienen LM, Vaysburd M, Cruickshank J, O'Connell K, Clark J, Mayes K, Higginson K, Lode HE, McAdam MB, Sandlie I, Andersen JT, James LC (2019)
   Complement C4 Prevents Viral Infection through Capsid Inactivation
   Cell Host Microbe, 25 (4), 617-629.e7
   DOI 10.1016/j.chom.2019.02.016, PubMed 30926239
8. Brunet M, van Gelder T, Åsberg A, Haufroid V, Hesselink DA, Langman L, Lemaitre F, Marquet P, Seger C, Shipkova M, Vinks A, Wallemacq P, Wieland E, Woillard JB, Barten MJ, Budde K, Colom H, Dieterlen MT, Elens L, Johnson-Davis KL, Kunicki PK, MacPhee I, Masuda S, Mathew BS, Millán O et al. (2019)
   Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report
   Ther Drug Monit, 41 (3), 261-307
   DOI 10.1097/FTD.0000000000000640, PubMed 31045868
9. Bruun LD, Kjeldstadli K, Temte V, Birdal M, Bachs L, Langødegård M, Strand DH, Gaare KI, Øiestad E, Høiseth G (2019)
   Detection Time of Oxazepam and Zopiclone in Urine and Oral Fluid after Experimental Oral Dosing
   J Anal Toxicol, 43 (5), 369-377
   DOI 10.1093/jat/bky083, PubMed 30615130
10. Bull Melsom C, Cosson MV, Ørstavik Ø, Lai NC, Hammond HK, Osnes JB, Skomedal T, Nikolaev V, Levy FO, Krobert KA (2019)
    Constitutive inhibitory G protein activity upon adenylyl cyclase-dependent cardiac contractility is limited to adenylyl cyclase type 6
    PLoS One, 14 (6), e0218110
    DOI 10.1371/journal.pone.0218110, PubMed 31173603
11. Calamera G, Li D, Ulsund AH, Kim JJ, Neely OC, Moltzau LR, Bjørnerem M, Paterson D, Kim C, Levy FO, Andressen KW (2019)
    FRET-based cyclic GMP biosensors measure low cGMP concentrations in cardiomyocytes and neurons
    Commun Biol, 2, 394
    DOI 10.1038/s42003-019-0641-x, PubMed 31701023
12. Cosson MV, Hiis HG, Moltzau LR, Levy FO, Krobert KA (2019)
    Knockout of adenylyl cyclase isoform 5 or 6 differentially modifies the β₁-adrenoceptor-mediated inotropic response
    J Mol Cell Cardiol, 131, 132-145
    DOI 10.1016/j.yjmcc.2019.04.017, PubMed 31009605
13. Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Carcas AJ, Borobia AM, Tong HY, Dávila-Fajardo C, Rodrigues Botton M, Bourgeois S, Deloukas P, Caldwell MD, Burmester JK, Berg RL, Cavallari LH, Drozda K, Huang M, Zhao LZ, Cen HJ, Gonzalez-Conejero R, Roldan V, Nakamura Y et al. (2019)
    Effect of CYP4F2, VKORC1, and CYP2C9 in Influencing Coumarin Dose: A Single-Patient Data Meta-Analysis in More Than 15,000 Individuals
    Clin Pharmacol Ther, 105 (6), 1477-1491
    DOI 10.1002/cpt.1323, PubMed 30506689
14. Foss S, Bottermann M, Jonsson A, Sandlie I, James LC, Andersen JT (2019)
    TRIM21-From Intracellular Immunity to Therapy
    Front Immunol, 10, 2049
    DOI 10.3389/fimmu.2019.02049, PubMed 31555278
15. Frost J, Bernard JP, Dietrichs ES, Kjeldstadli K, Riedel B, Skrastad RB, Vevelstad M, Helland A (2019)
    New recommendations for serum concentration measurements of central stimulant drugs
    Tidsskr. Nor. Laegeforen., 139 (13), 1230-1231
16. Granas AG, Halvorsen KH, Wendelbo J, Johannessen Landmark C (2019)
    Interdisciplinary medication review to improve pharmacotherapy for patients with intellectual disabilities
    Int J Clin Pharm, 41 (6), 1516-1525
    DOI 10.1007/s11096-019-00914-3, PubMed 31729635
17. Havnen GC, Truong MB, Do MH, Heitmann K, Holst L, Nordeng H (2019)
    Women's perspectives on the management and consequences of hyperemesis gravidarum - a descriptive interview study
    Scand J Prim Health Care, 37 (1), 30-40
    DOI 10.1080/02813432.2019.1569424, PubMed 30822254
18. Henning O, Johannessen Landmark C, Nakken KO, Lossius MI (2019)
    Nonadherence to treatment regimens in epilepsy from the patient's perspective and predisposing factors: Differences between intentional and unintentional lack of adherence
    Epilepsia, 60 (5), e58-e62
    DOI 10.1111/epi.14734, PubMed 30980675
19. Henning O, Johannessen Landmark C, Traeen B, Svendsen T, Farmen A, Nakken KO, Lossius M (2019)
    Sexual function in people with epilepsy: Similarities and differences with the general population
    Epilepsia, 60 (9), 1984-1992
    DOI 10.1111/epi.16311, PubMed 31407332
20. Henning O, Landmark CJ, Henning D, Nakken KO, Lossius MI (2019)
    Challenges in epilepsy-The perspective of Norwegian epilepsy patients
    Acta Neurol Scand, 140 (1), 40-47
    DOI 10.1111/ane.13098, PubMed 30963535
21. Henning O, Lossius MI, Lima M, Mevåg M, Villagran A, Nakken KO, Johannessen Landmark C (2019)
    Refractory epilepsy and nonadherence to drug treatment
    Epilepsia Open, 4 (4), 618-623
    DOI 10.1002/epi4.12367, PubMed 31819918
22. Jendresen C, Digre A, Cui H, Zhang X, Vlodavsky I, Li JP, Nilsson LNG (2019)
    Systemic LPS-induced Aβ-solubilization and clearance in AβPP-transgenic mice is diminished by heparanase overexpression
    Sci Rep, 9 (1), 4600
    DOI 10.1038/s41598-019-40999-4, PubMed 30872722
23. Johannessen Landmark C, Fløgstad I, Baftiu A, Syvertsen M, Enger U, Koht J, Johannessen SI (2019)
    Long-term follow-up with therapeutic drug monitoring of antiepileptic drugs in patients with juvenile myoclonic epilepsy
    Epilepsy Res, 155, 106148
    DOI 10.1016/j.eplepsyres.2019.05.016, PubMed 31195184
24. Johannessen Landmark C, Fløgstad I, Syvertsen M, Baftiu A, Enger U, Koht J, Johannessen SI (2019)
    Treatment and challenges with antiepileptic drugs in patients with juvenile myoclonic epilepsy
    Epilepsy Behav, 98 (Pt A), 110-116
    DOI 10.1016/j.yebeh.2019.05.021, PubMed 31330379
25. Klaasen RA, Egeland EJ, Chan J, Midtvedt K, Svensson M, Bolstad N, Fellström B, Holdaas H, Åsberg A, Bergan S, Vethe NT, Warren DJ (2019)
    A Fully Automated Method for the Determination of Serum Belatacept and Its Application in a Pharmacokinetic Investigation in Renal Transplant Recipients
    Ther Drug Monit, 41 (1), 11-18
    DOI 10.1097/FTD.0000000000000580, PubMed 30633722
26. Kristiansen O, Vethe NT, Fagerland MW, Bergan S, Munkhaugen J, Husebye E (2019)
    A novel direct method to determine adherence to atorvastatin therapy in patients with coronary heart disease
    Br J Clin Pharmacol, 85 (12), 2878-2885
    DOI 10.1111/bcp.14122, PubMed 31495943
27. Labzin LI, Bottermann M, Rodriguez-Silvestre P, Foss S, Andersen JT, Vaysburd M, Clift D, James LC (2019)
    Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection
    EMBO J, 38 (21), e101365
    DOI 10.15252/embj.2018101365, PubMed 31468569
28. Larsen Burns M, Kinge E, Stokke Opdal M, Johannessen SI, Johannessen Landmark C (2019)
    Therapeutic drug monitoring of gabapentin in various indications
    Acta Neurol Scand, 139 (5), 446-454
    DOI 10.1111/ane.13075, PubMed 30710348
29. Larsen Burns M, Nikanorova M, Baftiu A, Borg Rasmussen J, Johannessen SI, Johannessen Landmark C (2019)
    Pharmacokinetic Variability and Clinical Use of Lacosamide in Children and Adolescents in Denmark and Norway
    Ther Drug Monit, 41 (3), 340-347
    DOI 10.1097/FTD.0000000000000599, PubMed 30688870
30. Lode HE, Gjølberg TT, Foss S, Sivertsen MS, Brustugun J, Andersson Y, Jørstad ØK, Moe MC, Andersen JT (2019)
    A new method for pharmaceutical compounding and storage of anti-VEGF biologics for intravitreal use in silicone oil-free prefilled plastic syringes
    Sci Rep, 9 (1), 18021
    DOI 10.1038/s41598-019-54226-7, PubMed 31792234
31. Munkhaugen J, Vethe NT, Fagerland MW, Dammen T, Perk J, Gjertsen E, Otterstad JE, Gullestad L, Bergan S, Husebye E (2019)
    Statin-associated muscle symptoms in coronary patients: design of a randomized study
    Scand Cardiovasc J, 53 (3), 162-168
    DOI 10.1080/14017431.2019.1612085, PubMed 31030568
32. Maaland AF, Heyerdahl H, O'Shea A, Eiriksdottir B, Pascal V, Andersen JT, Kolstad A, Dahle J (2019)
    Targeting B-cell malignancies with the beta-emitting anti-CD37 radioimmunoconjugate ¹⁷⁷Lu-NNV003
    Eur J Nucl Med Mol Imaging, 46 (11), 2311-2321
    DOI 10.1007/s00259-019-04417-1, PubMed 31309259
33. Ndongson-Dongmo B, Lang GP, Mece O, Hechaichi N, Lajqi T, Hoyer D, Brodhun M, Heller R, Wetzker R, Franz M, Levy FO, Bauer R (2019)
    Reduced ambient temperature exacerbates SIRS-induced cardiac autonomic dysregulation and myocardial dysfunction in mice
    Basic Res Cardiol, 114 (3), 26
    DOI 10.1007/s00395-019-0734-1, PubMed 31016449
34. Nordengen K, Kirsebom BE, Henjum K, Selnes P, Gísladóttir B, Wettergreen M, Torsetnes SB, Grøntvedt GR, Waterloo KK, Aarsland D, Nilsson LNG, Fladby T (2019)
    Glial activation and inflammation along the Alzheimer's disease continuum
    J Neuroinflammation, 16 (1), 46
    DOI 10.1186/s12974-019-1399-2, PubMed 30791945
35. Pyzik M, Sand KMK, Hubbard JJ, Andersen JT, Sandlie I, Blumberg RS (2019)
    The Neonatal Fc Receptor (FcRn): A Misnomer?
    Front Immunol, 10, 1540
    DOI 10.3389/fimmu.2019.01540, PubMed 31354709
36. Skulberg AK, Åsberg A, Khiabani HZ, Røstad H, Tylleskar I, Dale O (2019)
    Pharmacokinetics of a novel, approved, 1.4-mg intranasal naloxone formulation for reversal of opioid overdose-a randomized controlled trial
    Addiction, 114 (5), 859-867
    DOI 10.1111/add.14552, PubMed 30644628
37. Sørensen O, Andersen AM, Larsen SG, Giercksky KE, Flatmark K (2019)
    Intraperitoneal mitomycin C improves survival compared to cytoreductive surgery alone in an experimental model of high-grade pseudomyxoma peritonei
    Clin Exp Metastasis, 36 (6), 511-518
    DOI 10.1007/s10585-019-09991-0, PubMed 31541325
38. Søraas A, Matsuyama M, de Lima M, Wald D, Buechner J, Gedde-Dahl T, Søraas CL, Chen B, Ferrucci L, Dahl JA, Horvath S, Matsuyama S (2019)
    Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells
    Aging Cell, 18 (2), e12897
    DOI 10.1111/acel.12897, PubMed 30712319
39. Temte V, Kjeldstadli K, Bruun LD, Birdal M, Bachs L, Karinen R, Middelkoop G, Øiestad E, Høiseth G (2019)
    An Experimental Study of Diazepam and Alprazolam Kinetics in Urine and Oral Fluid Following Single Oral Doses
    J Anal Toxicol, 43 (2), 104-111
    DOI 10.1093/jat/bky062, PubMed 30517712
40. Traaen GM, Øverland B, Aakerøy L, Hunt TE, Bendz C, Sande L, Aakhus S, Zaré H, Steinshamn S, Anfinsen OG, Loennechen JP, Gullestad L, Akre H (2019)
    Prevalence, risk factors, and type of sleep apnea in patients with paroxysmal atrial fibrillation
    Int J Cardiol Heart Vasc, 26, 100447
    DOI 10.1016/j.ijcha.2019.100447, PubMed 32140547
41. Tuv SS, Vethe NT, Bergan S, Nordal K (2019)
    Pharmacogenetics in personalised drug therapy
    Tidsskr. Nor. Laegeforen., 139 (8), 700-702
42. Vethe NT, Gustavsen MT, Midtvedt K, Lauritsen ME, Andersen AM, Åsberg A, Bergan S (2019)
    Tacrolimus Can Be Reliably Measured With Volumetric Absorptive Capillary Microsampling Throughout the Dose Interval in Renal Transplant Recipients
    Ther Drug Monit, 41 (5), 607-614
    DOI 10.1097/FTD.0000000000000655, PubMed 31584926
43. Vethe NT, Munkhaugen J, Andersen AM, Husebye E, Bergan S (2019)
    A Method for Direct Monitoring of Atorvastatin Adherence in Cardiovascular Disease Prevention: Quantification of the Total Exposure to Parent Drug and Major Metabolites Using 2-Channel Chromatography and Tandem Mass Spectrometry
    Ther Drug Monit, 41 (1), 19-28
    DOI 10.1097/FTD.0000000000000578, PubMed 30633723
44. Westergren T, Narum S, Klemp M (2019)
    Critical appraisal of adverse effects reporting in the 'Treatment for Adolescents With Depression Study (TADS)'
    BMJ Open, 9 (3), e026089
    DOI 10.1136/bmjopen-2018-026089, PubMed 30878988

Publications 2018

1. Andressen KW, Ulsund AH, Krobert KA, Lohse MJ, Bünemann M, Levy FO (2018)
   Related GPCRs couple differently to G_s: preassociation between G protein and 5-HT₇ serotonin receptor reveals movement of Gα_s upon receptor activation
   FASEB J, 32 (2), 1059-1069
   DOI 10.1096/fj.201700486R, PubMed 29079700
2. Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS (2018)
   Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). II. Drugs in more advanced clinical development
   Epilepsia, 59 (10), 1842-1866
   DOI 10.1111/epi.14555, PubMed 30368788
3. Bialer M, Johannessen SI, Koepp MJ, Levy RH, Perucca E, Tomson T, White HS (2018)
   Progress report on new antiepileptic drugs: A summary of the Fourteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIV). I. Drugs in preclinical and early clinical development
   Epilepsia, 59 (10), 1811-1841
   DOI 10.1111/epi.14557, PubMed 30368792
4. Eek AK, Strøm BO, Bakkehøi G, Stenberg-Nilsen H (2018)
   Anticoagulant-associated adverse drug reactions in 2013-15
   Tidsskr Nor Laegeforen, 138 (12)
   DOI 10.4045/tidsskr.17.0706, PubMed 30132616
5. Eide IA, Reinholt FP, Jenssen T, Hartmann A, Schmidt EB, Åsberg A, Bergan S, Brabrand K, Svensson M (2018)
   Effects of marine n-3 fatty acid supplementation in renal transplantation: A randomized controlled trial
   Am J Transplant, 19 (3), 790-800
   DOI 10.1111/ajt.15080, PubMed 30125457
6. Fjeld H, Stylianou E (2018)
   Hypersensitivity reactions with prolonged infusions of β-lactams?
   Clin Microbiol Infect, 25 (1), 121-122
   DOI 10.1016/j.cmi.2018.08.021, PubMed 30195470
7. Grevys A, Nilsen J, Sand KMK, Daba MB, Øynebråten I, Bern M, McAdam MB, Foss S, Schlothauer T, Michaelsen TE, Christianson GJ, Roopenian DC, Blumberg RS, Sandlie I, Andersen JT (2018)
   A human endothelial cell-based recycling assay for screening of FcRn targeted molecules
   Nat Commun, 9 (1), 621
   DOI 10.1038/s41467-018-03061-x, PubMed 29434196
8. Havig SM, Lea D, Krpo M, Skari RM, Gustavsen I, Høiseth G (2018)
   Fatal Adverse Event with Dabigatran in Elderly Patient with Reduced Kidney Function
   Basic Clin Pharmacol Toxicol, 123 (2), 221-226
   DOI 10.1111/bcpt.12985, PubMed 29438599
9. Heldal K, Midtvedt K, Hartmann A, Reisaeter AV, Heldal TF, Bergan S, Salvador CL, Åsberg A (2018)
   Estimated glomerular filtration rate in stable older kidney transplant recipients-are present algorithms valid? A national cross-sectional cohort study
   Transpl Int, 31 (6), 629-638
   DOI 10.1111/tri.13137, PubMed 29453878
10. Henjum K, Quist-Paulsen E, Zetterberg H, Blennow K, Nilsson LNG, Watne LO (2018)
    CSF sTREM2 in delirium-relation to Alzheimer's disease CSF biomarkers Aβ42, t-tau and p-tau
    J Neuroinflammation, 15 (1), 304
    DOI 10.1186/s12974-018-1331-1, PubMed 30390679
11. Hiis HG, Cosson MV, Dahl CP, Fiane AE, Levy FO, Andersen GØ, Krobert KA (2018)
    Hypothermia elongates the contraction-relaxation cycle in explanted human failing heart decreasing the time for ventricular filling during diastole
    Am J Physiol Heart Circ Physiol, 315 (5), H1137-H1147
    DOI 10.1152/ajpheart.00208.2018, PubMed 30004809
12. Hov KR, Neerland BE, Andersen AM, Undseth Ø, Wyller VB, MacLullich AMJ, Skovlund E, Qvigstad E, Wyller TB (2018)
    The use of clonidine in elderly patients with delirium; pharmacokinetics and hemodynamic responses
    BMC Pharmacol Toxicol, 19 (1), 29
    DOI 10.1186/s40360-018-0218-1, PubMed 29884231
13. Johannessen Landmark C, Farmen AH, Burns ML, Baftiu A, Lossius MI, Johannessen SI, Tomson T (2018)
    Pharmacokinetic variability of valproate during pregnancy - Implications for the use of therapeutic drug monitoring
    Epilepsy Res, 141, 31-37
    DOI 10.1016/j.eplepsyres.2018.02.004, PubMed 29453075
14. Klaasen RA, Bergan S, Bremer S, Daleq L, Andersen AM, Midtvedt K, Skauby MH, Vethe NT (2018)
    Longitudinal Study of Tacrolimus in Lymphocytes During the First Year After Kidney Transplantation
    Ther Drug Monit, 40 (5), 558-566
    DOI 10.1097/FTD.0000000000000539, PubMed 30086087
15. Krogstad V, Vethe NT, Robertsen I, Hasvold G, Ose AD, Hermann M, Andersen AM, Chan J, Skauby M, Svensson MHS, Åsberg A, Christensen H (2018)
    Determination of Tacrolimus Concentration and Protein Expression of P-Glycoprotein in Single Human Renal Core Biopsies
    Ther Drug Monit, 40 (3), 292-300
    DOI 10.1097/FTD.0000000000000510, PubMed 29578937
16. Krug O, Thomas A, Malerød-Fjeld H, Dehnes Y, Laussmann T, Feldmann I, Sickmann A, Thevis M (2018)
    Analysis of new growth promoting black market products
    Growth Horm IGF Res, 41, 1-6
    DOI 10.1016/j.ghir.2018.05.001, PubMed 29864719
17. Munkhaugen J, Ruddox V, Halvorsen S, Dammen T, Fagerland MW, Hernæs KH, Vethe NT, Prescott E, Jensen SE, Rødevand O, Jortveit J, Bendz B, Schirmer H, Køber L, Bøtker HE, Larsen AI, Vikenes K, Steigen T, Wiseth R, Pedersen T, Edvardsen T, Otterstad JE, Atar D (2018)
    BEtablocker Treatment After acute Myocardial Infarction in revascularized patients without reduced left ventricular ejection fraction (BETAMI): Rationale and design of a prospective, randomized, open, blinded end point study
    Am Heart J, 208, 37-46
    DOI 10.1016/j.ahj.2018.10.005, PubMed 30530121
18. Müller LD, Opdal MS (2018)
    Developing a rapid semi-automated sample preparation with alkaline hydrolysis in a 96-well plate for quantification of 11-nor-Δ9-tetrahydrocannabinol-9-carboxylic acid in urine samples by UHPLC-MS/MS
    J Pharm Biomed Anal, 161, 296-304
    DOI 10.1016/j.jpba.2018.08.045, PubMed 30189411
19. Nilsen J, Sandlie I, Roopenian DC, Andersen JT (2018)
    Animal models for evaluation of albumin-based therapeutics
    Curr. Opin. Chem. Eng., 19, 68-76
    DOI 10.1016/j.coche.2017.11.007
20. Reimers A, Berg JA, Burns ML, Brodtkorb E, Johannessen SI, Johannessen Landmark C (2018)
    Reference ranges for antiepileptic drugs revisited: a practical approach to establish national guidelines
    Drug Des Devel Ther, 12, 271-280
    DOI 10.2147/DDDT.S154388, PubMed 29467570
21. Reiter L, Stenberg-Nilsen H (2018)
    Too high vitamin D content in dietary supplements?
    Tidsskr. Nor. Laegeforen., 138 (1), 20-21
22. Serk TT, Le Nygaard I, Kvan E, Frost J, Aronsen L, Narum S, Bjanes T (2018)
    Immediate telephonic alerting of deviating pharmacological test results
    Tidsskr. Nor. Laegeforen., 138 (18), 1694-1695
23. Skogestad J, Aronsen JM (2018)
    Hypokalemia-Induced Arrhythmias and Heart Failure: New Insights and Implications for Therapy
    Front Physiol, 9, 1500
    DOI 10.3389/fphys.2018.01500, PubMed 30464746
24. Stapleton NM, Armstrong-Fisher SS, Andersen JT, van der Schoot CE, Porter C, Page KR, Falconer D, de Haas M, Williamson LM, Clark MR, Vidarsson G, Armour KL (2018)
    Human IgG lacking effector functions demonstrate lower FcRn-binding and reduced transplacental transport
    Mol Immunol, 95, 1-9
    DOI 10.1016/j.molimm.2018.01.006, PubMed 29367080
25. Syvertsen M, Fløgstad I, Enger U, Landmark CJ, Koht J (2018)
    Antiepileptic drug withdrawal in juvenile myoclonic epilepsy
    Acta Neurol Scand, 139 (2), 192-198
    DOI 10.1111/ane.13042, PubMed 30378684
26. Traaen GM, Aakerøy L, Hunt TE, Øverland B, Lyseggen E, Aukrust P, Ueland T, Helle-Valle T, Steinshamn S, Edvardsen T, Khiabani Zaré H, Aakhus S, Akre H, Anfinsen OG, Loennechen JP, Gullestad L (2018)
    Treatment of sleep apnea in patients with paroxysmal atrial fibrillation: design and rationale of a randomized controlled trial
    Scand Cardiovasc J, 52 (6), 372-377
    DOI 10.1080/14017431.2019.1567933, PubMed 30638392
27. Tvete IF, Bjørner T, Skomedal T (2018)
    Mental Health and Disability Pension Onset: Changes in Consumption of Antianxiety and Hypnotic Drugs
    Health Serv Res Manag Epidemiol, 5, 2333392818792683
    DOI 10.1177/2333392818792683, PubMed 30182036

Publications 2017

1. Ahamed M, Vermeulen K, Schnekenburger M, Moltzau LR, Levy FO, Marton J, Froeyen M, Olberg DE, Diederich M, Bormans G (2017)
   Synthesis, Enzyme Assays and Molecular Docking Studies of Fluorinated Bioisosteres of Santacruzamate A as Potential HDAC Tracers
   Lett. Drug Des. Discov., 14 (7), 787-797
   DOI 10.2174/1570180813666161101152943
2. Ask IS, Føreid S, Knatten CK, Wallace SC, Gadeholt G (2017)
   [Detection of nitromethane in blood]
   Tidsskr Nor Laegeforen, 137 (2), 112
   DOI 10.4045/tidsskr.16.0100, PubMed 28127074
3. Baftiu A, Feet SA, Larsson PG, Burns ML, Henning O, Sætre E, Molden E, Granas AG, Johannessen SI, Landmark CJ (2017)
   Utilisation and polypharmacy aspects of antiepileptic drugs in elderly versus younger patients with epilepsy: A pharmacoepidemiological study of CNS-active drugs in Norway, 2004-2015
   Epilepsy Res, 139, 35-42
   DOI 10.1016/j.eplepsyres.2017.11.001, PubMed 29175562
4. Baftiu A, Landmark CJ, Rusten IR, Feet SA, Johannessen SI, Larsson PG (2017)
   Erratum to: Changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders-A pharmacoepidemiological study and clinical implications
   Eur J Clin Pharmacol, 73 (6), 791-792
   DOI 10.1007/s00228-017-2252-0, PubMed 28389679
5. Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS (2017)
   Progress report on new antiepileptic drugs: A summary of the Thirteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XIII)
   Epilepsia, 58 (2), 181-221
   DOI 10.1111/epi.13634, PubMed 28111749
6. Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS, Koepp MJ (2017)
   Seizure detection and neuromodulation: A summary of data presented at the XIII conference on new antiepileptic drug and devices (EILAT XIII)
   Epilepsy Res, 130, 27-36
   DOI 10.1016/j.eplepsyres.2017.01.004, PubMed 28113141
7. Bremer S, Vethe NT, Skauby M, Kasbo M, Johansson ED, Midtvedt K, Bergan S (2017)
   NFAT-regulated cytokine gene expression during tacrolimus therapy early after renal transplantation
   Br J Clin Pharmacol, 83 (11), 2494-2502
   DOI 10.1111/bcp.13367, PubMed 28686294
8. Burns ML, Lang AM (2017)
   The authors reply
   Pediatr Crit Care Med, 18 (1), 98
   DOI 10.1097/PCC.0000000000001023, PubMed 28060165
9. Eek AK, Øie E, Granas AG (2017)
   Prescribing of NOACs has outnumbered warfarin: exploring how physicians choose anticoagulant treatments
   Eur J Clin Pharmacol, 74 (3), 323-330
   DOI 10.1007/s00228-017-2374-4, PubMed 29149366
10. Egeland EJ, Robertsen I, Hermann M, Midtvedt K, Størset E, Gustavsen MT, Reisæter AV, Klaasen R, Bergan S, Holdaas H, Hartmann A, Åsberg A (2017)
    High Tacrolimus Clearance Is a Risk Factor for Acute Rejection in the Early Phase After Renal Transplantation
    Transplantation, 101 (8), e273-e279
    DOI 10.1097/TP.0000000000001796, PubMed 28452920
11. Føreid S, Gadeholt G (2017)
    Beta-hydroxybutyrate and pyroglutamate can be included in a rapid GC-MS screening method for differential diagnosis of metabolic acidosis
    Scand J Clin Lab Invest, 77 (2), 149-152
    DOI 10.1080/00365513.2016.1278261, PubMed 28150506
12. Havig SM, Høiseth G, Strand MC, Karinen RA, Brochmann GW, Strand DH, Bachs L, Vindenes V (2017)
    THC and CBD in blood samples and seizures in Norway: Does CBD affect THC-induced impairment in apprehended subjects?
    Forensic Sci Int, 276, 12-17
    DOI 10.1016/j.forsciint.2017.04.006, PubMed 28463706
13. Hjelmeland K, Gustavsen I, Øiestad EL, Øiestad ÅML, Høiseth G, Mørland J (2017)
    Zopiclone concentrations in oral fluid and blood after, administration of therapeutic doses of zopiclone
    Forensic Sci Int, 278, 177-183
    DOI 10.1016/j.forsciint.2017.07.004, PubMed 28735217
14. Jendresen C, Daws MR, Nilsson LNG (2017)
    An improved CPRG colorimetric ligand-receptor signal transduction assay based on beta-galactosidase activity in mammalian BWZ-reporter cells
    J Pharmacol Toxicol Methods, 90, 67-75
    DOI 10.1016/j.vascn.2017.11.004, PubMed 29203451
15. Jendresen C, Årskog V, Daws MR, Nilsson LN (2017)
    The Alzheimer's disease risk factors apolipoprotein E and TREM2 are linked in a receptor signaling pathway
    J Neuroinflammation, 14 (1), 59
    DOI 10.1186/s12974-017-0835-4, PubMed 28320424
16. Johannessen Landmark C, Burns ML, Baftiu A, Farmen AH, Lossius MI, Johannessen SI, Tomson T (2017)
    Pharmacokinetic variability of valproate in women of childbearing age
    Epilepsia, 58 (10), e142-e146
    DOI 10.1111/epi.13872, PubMed 28833045
17. Krogh N, Rzeppa S, Dyreborg A, Dehnes Y, Hemmersbach P, Backer V, Hostrup M (2017)
    Terbutaline Accumulates in Blood and Urine after Daily Therapeutic Inhalation
    Med Sci Sports Exerc, 49 (6), 1236-1243
    DOI 10.1249/MSS.0000000000001199, PubMed 28072631
18. Meier S, Andressen KW, Aronsen JM, Sjaastad I, Hougen K, Skomedal T, Osnes JB, Qvigstad E, Levy FO, Moltzau LR (2017)
    PDE3 inhibition by C-type natriuretic peptide-induced cGMP enhances cAMP-mediated signaling in both non-failing and failing hearts
    Eur J Pharmacol, 812, 174-183
    DOI 10.1016/j.ejphar.2017.07.014, PubMed 28697992
19. Midtvedt K, Bergan S, Reisæter AV, Vikse BE, Åsberg A (2017)
    Exposure to Mycophenolate and Fatherhood
    Transplantation, 101 (7), e214-e217
    DOI 10.1097/TP.0000000000001747, PubMed 28346297
20. Midtvedt K, Holdaas H, Bergan S, Åsberg A (2017)
    Costimulation Blockade: America First, Canada Second … What About Norway?
    Am J Transplant, 17 (8), 2230
    DOI 10.1111/ajt.14351, PubMed 28508535
21. Pisani LR, Nikanorova M, Landmark CJ, Johannessen SI, Pisani F (2017)
    Specific Patient Features Affect Antiepileptic Drug Therapy Decisions: Focus on Gender, Age, and Psychiatric Comorbidities
    Curr Pharm Des, 23 (37), 5639-5648
    DOI 10.2174/1381612823666170926103631, PubMed 28950817
22. Pitarch-Motellón J, Roig-Navarro AF, Sancho JV, Ibáñez M, Fabregat-Cabello N, Pozo OJ, Ventura R, García Alonso JI, Rodríguez-González P, González Gago A, Ereño Artabe A, Van Eenoo P, Deventer K, Dehnes Y, Rzeppa S (2017)
    Evaluation of uncertainty sources in the determination of testosterone in urine by calibration-based and isotope dilution quantification using ultra high performance liquid chromatography tandem mass spectrometry
    J Chromatogr A, 1508, 73-80
    DOI 10.1016/j.chroma.2017.05.072, PubMed 28601363
23. Raeder J, Dahl V, Markestad A, Nordbo A, Roaldset AH, Stubhaug A, Soeberg B, Willke A, Aasbo V, Johansen PW (2017)
    From ketobemidone to morphine or oxycodone
    Tidsskr. Nor. Laegeforen., 137 (3), 170
24. Reimers A, Berg JA, Burns ML, Landmark CJ (2017)
    Common reference range for antiepileptics
    Tidsskr. Nor. Laegeforen., 137 (12-13), 864-865
25. Reimers A, Berg JA, Burns ML, Landmark CJ (2017)
    Harmonised reference ranges for antiepileptic drugs
    Tidsskr Nor Laegeforen, 137 (12-13), 864-865
    DOI 10.4045/tidsskr.17.0392, PubMed 28655236
26. Salvador CL, Hartmann A, Åsberg A, Bergan S, Rowe AD, Mørkrid L (2017)
    Estimating Glomerular Filtration Rate in Kidney Transplant Recipients: Comparing a Novel Equation With Commonly Used Equations in this Population
    Transplant Direct, 3 (12), e332
    DOI 10.1097/TXD.0000000000000742, PubMed 29536033
27. Skauby RH, Bjerre A, Sæves I, Vethe NT, Bremer S, Svarstad A, Bergan S (2017)
    Prednisolone and Prednisone Pharmacokinetics in Pediatric Renal Transplant Recipients-A Prospective Study
    Ther Drug Monit, 39 (5), 472-482
    DOI 10.1097/FTD.0000000000000439, PubMed 28749817
28. Strand TE, Khiabani HZ, Boico A, Radiloff D, Zhao Y, Hamilton KL, Christians U, Klawitter J, Noveck RJ, Piantadosi CA, Bell C, Irwin D, Schroeder T (2017)
    The novel combination of theophylline and bambuterol as a potential treatment of hypoxemia in humans
    Can J Physiol Pharmacol, 95 (9), 1009-1018
    DOI 10.1139/cjpp-2016-0635, PubMed 28467859
29. Størset E, Hole K, Midtvedt K, Bergan S, Molden E, Åsberg A (2017)
    The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation
    Br J Clin Pharmacol, 83 (7), 1457-1465
    DOI 10.1111/bcp.13248, PubMed 28146606
30. Størset E, Hole K, Midtvedt K, Bergan S, Molden E, Åsberg A (2017)
    Response to: 'Response to: Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'
    Br J Clin Pharmacol, 83 (6), 1357-1358
    DOI 10.1111/bcp.13276, PubMed 28374426
31. Svendsen T, Brodtkorb E, Baftiu A, Burns ML, Johannessen SI, Johannessen Landmark C (2017)
    Therapeutic Drug Monitoring of Lacosamide in Norway: Focus on Pharmacokinetic Variability, Efficacy and Tolerability
    Neurochem Res, 42 (7), 2077-2083
    DOI 10.1007/s11064-017-2234-8, PubMed 28349359
32. Torp HA, Gustavsen I, Romundstad L (2017)
    A botanical anesthesia
    Tidsskr. Nor. Laegeforen., 137 (23-24), 1924-1928
33. Torp HA, Gustavsen I, Romundstad L (2017)
    [A botanical anesthesia]
    Tidsskr Nor Laegeforen, 137 (23-24)
    DOI 10.4045/tidsskr.17.0659, PubMed 29231661
34. Westergren T, Debernard KA (2017)
    Discrepancies in paper by Chiam et al.: The haemodynamic effects of intravenous paracetamol
    Br J Clin Pharmacol, 83 (2), 435
    DOI 10.1111/bcp.13182, PubMed 28090696
35. Westergren T, Narum S, Klemp M (2017)
    Characterization of gastrointestinal adverse effects reported in clinical studies of corticosteroid therapy
    J Clin Epidemiol, 94, 19-26
    DOI 10.1016/j.jclinepi.2017.10.018, PubMed 29113937
36. Ødegård J, Sondresen JE, Aasrum M, Tveteraas IH, Guren TK, Christoffersen T, Thoresen GH (2017)
    Differential effects of epidermal growth factor (EGF) receptor ligands on receptor binding, downstream signalling pathways and DNA synthesis in hepatocytes
    Growth Factors, 35 (6), 239-248
    DOI 10.1080/08977194.2018.1453506, PubMed 29582692

Publications 2016

1. Baftiu A, Johannessen Landmark C, Rusten IR, Feet SA, Johannessen SI, Larsson PG (2016)
   Changes in utilisation of antiepileptic drugs in epilepsy and non-epilepsy disorders-a pharmacoepidemiological study and clinical implications
   Eur J Clin Pharmacol, 72 (10), 1245-1254
   DOI 10.1007/s00228-016-2092-3, PubMed 27411937
2. Bjørnebekk A, Walhovd KB, Jørstad ML, Due-Tønnessen P, Hullstein IR, Fjell AM (2016)
   Structural Brain Imaging of Long-Term Anabolic-Androgenic Steroid Users and Nonusing Weightlifters
   Biol Psychiatry, 82 (4), 294-302
   DOI 10.1016/j.biopsych.2016.06.017, PubMed 27616036
3. Brunet M, Shipkova M, van Gelder T, Wieland E, Sommerer C, Budde K, Haufroid V, Christians U, López-Hoyos M, Barten MJ, Bergan S, Picard N, Millán López O, Marquet P, Hesselink DA, Noceti O, Pawinski T, Wallemacq P, Oellerich M (2016)
   Barcelona Consensus on Biomarker-Based Immunosuppressive Drugs Management in Solid Organ Transplantation
   Ther Drug Monit, 38 Suppl 1, S1-20
   DOI 10.1097/FTD.0000000000000287, PubMed 26977997
4. Braadland PR, Grytli HH, Ramberg H, Katz B, Kellman R, Gauthier-Landry L, Fazli L, Krobert KA, Wang W, Levy FO, Bjartell A, Berge V, Rennie PS, Mellgren G, Mælandsmo GM, Svindland A, Barbier O, Taskén KA (2016)
   Low β₂-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism
   Oncotarget, 7 (2), 1878-94
   DOI 10.18632/oncotarget.6479, PubMed 26646591
5. Burns ML, Baftiu A, Opdal MS, Johannessen SI, Landmark CJ (2016)
   Therapeutic Drug Monitoring of Clobazam and Its Metabolite-Impact of Age and Comedication on Pharmacokinetic Variability
   Ther Drug Monit, 38 (3), 350-7
   DOI 10.1097/FTD.0000000000000272, PubMed 26751267
6. Burns ML, Stensvold HJ, Risnes K, Guthe HJ, Astrup H, Nordhov SM, Selberg TR, Rønnestad A, Lang AM, Norwegian Neonatal Network (2016)
   Inotropic Therapy in Newborns, A Population-Based National Registry Study
   Pediatr Crit Care Med, 17 (10), 948-956
   DOI 10.1097/PCC.0000000000000898, PubMed 27500723
7. Damkier P, Passier A, Bo Petersen L, Havnen G, Thestrup Pedersen AJ (2016)
   Changing of the guards: EMA warning on paternal use of mycophenolate mofetil: An unnecessary and insufficiently substantiated precaution
   Birth Defects Res A Clin Mol Teratol, 106 (10), 860-861
   DOI 10.1002/bdra.23556, PubMed 27678452
8. Dyreborg A, Krogh N, Backer V, Rzeppa S, Hemmersbach P, Hostrup M (2016)
   Pharmacokinetics of Oral and Inhaled Terbutaline after Exercise in Trained Men
   Front Pharmacol, 7, 150
   DOI 10.3389/fphar.2016.00150, PubMed 27375484
9. Eikemo H, Moltzau LR, Hussain RI, Nguyen CH, Qvigstad E, Levy FO, Skomedal T, Osnes JB (2016)
   CaMKII in addition to MLCK contributes to phosphorylation of regulatory light chain in cardiomyocytes
   Biochem Biophys Res Commun, 471 (1), 219-25
   DOI 10.1016/j.bbrc.2016.01.132, PubMed 26809094
10. Eikemo H, Moltzau LR, Nguyen CHT, Levy FO, Skomedal T, Osnes JB (2016)
    CaMKII and at least two unidentified kinases phosphorylate regulatory light chain in non-contracting cardiomyocytes
    Biochem Biophys Res Commun, 477 (1), 14-19
    DOI 10.1016/j.bbrc.2016.05.138, PubMed 27237977
11. Gottås A, Arnestad M, Halvorsen PS, Bachs LC, Høiseth G (2016)
    Pharmacokinetics of heroin and its metabolites in vitreous humor and blood in a living pig model
    Forensic Toxicol, 34 (2), 277-285
    DOI 10.1007/s11419-016-0315-z, PubMed 27660664
12. Haga C, Opdal MS, Tuv SS, Zahl PH, Stenberg-Nilsen H (2016)
    [Drug safety associated with the change of digitalis drug in Norway]
    Tidsskr Nor Laegeforen, 136 (20), 1714-1718
    DOI 10.4045/tidsskr.15.0161, PubMed 27830905
13. Halden TA, Egeland EJ, Åsberg A, Hartmann A, Midtvedt K, Khiabani HZ, Holst JJ, Knop FK, Hornum M, Feldt-Rasmussen B, Jenssen T (2016)
    GLP-1 Restores Altered Insulin and Glucagon Secretion in Posttransplantation Diabetes
    Diabetes Care, 39 (4), 617-24
    DOI 10.2337/dc15-2383, PubMed 26908914
14. Heitmann K, Havnen GC, Holst L, Nordeng H (2016)
    Pregnancy outcomes after prenatal exposure to echinacea: the Norwegian Mother and Child Cohort Study
    Eur J Clin Pharmacol, 72 (5), 623-30
    DOI 10.1007/s00228-016-2021-5, PubMed 26895223
15. Heitmann K, Solheimsnes A, Havnen GC, Nordeng H, Holst L (2016)
    Treatment of nausea and vomiting during pregnancy -a cross-sectional study among 712 Norwegian women
    Eur J Clin Pharmacol, 72 (5), 593-604
    DOI 10.1007/s00228-016-2012-6, PubMed 26815908
16. Helland A, Berg JA, Gustavsen I, Nordal K, Hilberg T, Aronsen L, Arnestad M, Narum S (2016)
    Serum concentration measurements of addictive drugs
    Tidsskr Nor Laegeforen, 136 (5), 400-2
    DOI 10.4045/tidsskr.16.0030, PubMed 26983140
17. Henjum K, Almdahl IS, Årskog V, Minthon L, Hansson O, Fladby T, Nilsson LN (2016)
    Cerebrospinal fluid soluble TREM2 in aging and Alzheimer's disease
    Alzheimers Res Ther, 8 (1), 17
    DOI 10.1186/s13195-016-0182-1, PubMed 27121148
18. Johannessen Landmark C, Henning O, Johannessen SI (2016)
    Proconvulsant effects of antidepressants - What is the current evidence?
    Epilepsy Behav, 61, 287-291
    DOI 10.1016/j.yebeh.2016.01.029, PubMed 26926001
19. Johannessen Landmark C, Svendsen T, Dinarevic J, Kufaas RF, Reimers A, Brodtkorb E, Baftiu A, Burns ML, Johannessen SI (2016)
    The Impact of Pharmacokinetic Interactions With Eslicarbazepine Acetate Versus Oxcarbazepine and Carbamazepine in Clinical Practice
    Ther Drug Monit, 38 (4), 499-505
    DOI 10.1097/FTD.0000000000000306, PubMed 27414974
20. Kloster-Jensen K, Sahraoui A, Vethe NT, Korsgren O, Bergan S, Foss A, Scholz H (2016)
    Treatment with Tacrolimus and Sirolimus Reveals No Additional Adverse Effects on Human Islets In Vitro Compared to Each Drug Alone but They Are Reduced by Adding Glucocorticoids
    J Diabetes Res, 2016, 4196460
    DOI 10.1155/2016/4196460, PubMed 26885529
21. Kong XY, Feng YZ, Eftestøl E, Kase ET, Haugum H, Eskild W, Rustan AC, Thoresen GH (2016)
    Increased glucose utilization and decreased fatty acid metabolism in myotubes from Glmp(gt/gt) mice
    Arch Physiol Biochem, 122 (1), 36-45
    DOI 10.3109/13813455.2015.1120752, PubMed 26707125
22. Kreiberg M, Becker V, Jessen S, Rzeppa S, Hemmersbach P, Backer V, Hostrup M (2016)
    Influence of exercise in normal and hot ambient conditions on the pharmacokinetics of inhaled terbutaline in trained men
    Scand J Med Sci Sports, 27 (7), 692-703
    DOI 10.1111/sms.12697, PubMed 27167471
23. Krogh N, Backer V, Rzeppa S, Hemmersbach P, Hostrup M (2016)
    Pharmacokinetics of nebulized and oral procaterol in asthmatic and non-asthmatic subjects in relation to doping analysis
    Drug Test Anal, 8 (10), 1056-1064
    DOI 10.1002/dta.1935, PubMed 26990656
24. Landmark CJ, Johannessen SI, Tomson T (2016)
    Dosing strategies for antiepileptic drugs: from a standard dose for all to individualised treatment by implementation of therapeutic drug monitoring
    Epileptic Disord, 18 (4), 367-383
    DOI 10.1684/epd.2016.0880, PubMed 27965183
25. Lund J, Stensrud C, Rajender, Bohov P, Thoresen GH, Berge RK, Wright M, Kamal A, Rustan AC, Miller AD, Skorve J (2016)
    The molecular structure of thio-ether fatty acids influences PPAR-dependent regulation of lipid metabolism
    Bioorg Med Chem, 24 (6), 1191-203
    DOI 10.1016/j.bmc.2016.01.045, PubMed 26874397
26. Mevaag M, Henning O, Baftiu A, Granas AG, Johannessen SI, Nakken KO, Johannessen Landmark C (2016)
    Discrepancies between physicians' prescriptions and patients' use of antiepileptic drugs
    Acta Neurol Scand, 135 (1), 80-87
    DOI 10.1111/ane.12578, PubMed 26923477
27. Moen B, Henjum K, Måge I, Knutsen SH, Rud I, Hetland RB, Paulsen JE (2016)
    Effect of Dietary Fibers on Cecal Microbiota and Intestinal Tumorigenesis in Azoxymethane Treated A/J Min/+ Mice
    PLoS One, 11 (5), e0155402
    DOI 10.1371/journal.pone.0155402, PubMed 27196124
28. Narum S, Brørs O, Stokland O, Kringen MK (2016)
    Mortality among head trauma patients taking preinjury antithrombotic agents: a retrospective cohort analysis from a Level 1 trauma centre
    BMC Emerg Med, 16 (1), 29
    DOI 10.1186/s12873-016-0094-1, PubMed 27485307
29. Norum HM, Kolberg ES, Solhaug V, Nordal K, Aukrust P (2016)
    Rhabdomyolysis and capillary leak syndrome in a patient treated with topical imiquimod
    Int J Dermatol, 55 (9), 1030-2
    DOI 10.1111/ijd.13255, PubMed 27061736
30. Olberg DE, Bauer N, Andressen KW, Hjørnevik T, Cumming P, Levy FO, Klaveness J, Haraldsen I, Sutcliffe JL (2016)
    Brain penetrant small molecule (18)F-GnRH receptor (GnRH-R) antagonists: Synthesis and preliminary positron emission tomography imaging in rats
    Nucl Med Biol, 43 (8), 478-89
    DOI 10.1016/j.nucmedbio.2016.05.003, PubMed 27236283
31. Picard N, Bergan S, Marquet P, van Gelder T, Wallemacq P, Hesselink DA, Haufroid V (2016)
    Pharmacogenetic Biomarkers Predictive of the Pharmacokinetics and Pharmacodynamics of Immunosuppressive Drugs
    Ther Drug Monit, 38 Suppl 1, S57-69
    DOI 10.1097/FTD.0000000000000255, PubMed 26469711
32. Rzeppa S, Viet L (2016)
    Analysis of sulfate metabolites of the doping agents oxandrolone and danazol using high performance liquid chromatography coupled to tandem mass spectrometry
    J Chromatogr B Analyt Technol Biomed Life Sci, 1029-1030, 1-9
    DOI 10.1016/j.jchromb.2016.06.028, PubMed 27394004
33. Rzeppa S, Viet LN (2016)
    Analysis of tolvaptan and its metabolites in sports drug testing by high-performance liquid chromatography coupled to tandem mass spectrometry
    Drug Test Anal, 8 (10), 1090-1094
    DOI 10.1002/dta.1933, PubMed 26768215
34. Sakshaug S, Handal M, Hjellvik V, Berg C, Ripel Å, Gustavsen I, Mørland J, Skurtveit S (2016)
    Long-term Use of Z-Hypnotics and Co-medication with Benzodiazepines and Opioids
    Basic Clin Pharmacol Toxicol, 120 (3), 292-298
    DOI 10.1111/bcpt.12684, PubMed 27717229
35. Størset E, Hole K, Midtvedt K, Bergan S, Molden E, Åsberg A (2016)
    Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance
    Br J Clin Pharmacol, 83 (6), 1350-1352
    DOI 10.1111/bcp.13188, PubMed 28008657
36. Størset E, von Düring ME, Godang K, Bergan S, Midtvedt K, Åsberg A (2016)
    Prediction of Fat-Free Mass in Kidney Transplant Recipients
    Ther Drug Monit, 38 (4), 439-46
    DOI 10.1097/FTD.0000000000000305, PubMed 27019101
37. Størset E, Åsberg A, Hartmann A, Reisaeter AV, Holdaas H, Skauby M, Bergan S, Midtvedt K (2016)
    Low-target tacrolimus in de novo standard risk renal transplant recipients: A single-centre experience
    Nephrology (Carlton), 21 (10), 821-7
    DOI 10.1111/nep.12738, PubMed 26854648
38. Svendsen T, Brodtkorb E, Reimers A, Molden E, Sætre E, Johannessen SI, Johannessen Landmark C (2016)
    Pharmacokinetic variability, efficacy and tolerability of eslicarbazepine acetate-A national approach to the evaluation of therapeutic drug monitoring data and clinical outcome
    Epilepsy Res, 129, 125-131
    DOI 10.1016/j.eplepsyres.2016.12.001, PubMed 28043062
39. Tekpli X, Urbanucci A, Hashim A, Vågbø CB, Lyle R, Kringen MK, Staff AC, Dybedal I, Mills IG, Klungland A, Staerk J (2016)
    Changes of 5-hydroxymethylcytosine distribution during myeloid and lymphoid differentiation of CD34+ cells
    Epigenetics Chromatin, 9, 21
    DOI 10.1186/s13072-016-0070-8, PubMed 27252783
40. Tuv SS, Krabseth HM, Strand MC, Karinen RA, Wiik E, Vevelstad MS, Westin AA, Øiestad EL, Vindenes V (2016)
    New designer drugs from the web
    Tidsskr Nor Laegeforen, 136 (8), 721-3
    DOI 10.4045/tidsskr.15.1276, PubMed 27143463
41. Villar IC, Bubb KJ, Moyes AJ, Steiness E, Gulbrandsen T, Levy FO, Hobbs AJ (2016)
    Functional pharmacological characterization of SER100 in cardiovascular health and disease
    Br J Pharmacol, 173 (23), 3386-3401
    DOI 10.1111/bph.13634, PubMed 27667485
42. Westlye LT, Kaufmann T, Alnæs D, Hullstein IR, Bjørnebekk A (2016)
    Brain connectivity aberrations in anabolic-androgenic steroid users
    Neuroimage Clin, 13, 62-69
    DOI 10.1016/j.nicl.2016.11.014, PubMed 27942448
43. Aasrum M, Brusevold IJ, Christoffersen T, Thoresen GH (2016)
    HGF-induced DNA synthesis in hepatocytes is suppressed by p38
    Growth Factors, 34 (5-6), 217-223
    DOI 10.1080/08977194.2017.1285765, PubMed 28209091
44. Åstrand OAH, Viktorsson EÖ, Kristensen AL, Ekeberg D, Røberg-Larsen H, Wilson SR, Gabrielsen M, Sylte I, Rustan AC, Thoresen GH, Rongved P, Kase ET (2016)
    Synthesis, in vitro and in vivo biological evaluation of new oxysterols as modulators of the liver X receptors
    J Steroid Biochem Mol Biol, 165 (Pt B), 323-330
    DOI 10.1016/j.jsbmb.2016.07.010, PubMed 27471149

Publications 2015

1. Baftiu A, Johannessen Landmark C, Nikaj V, Neslein IL, Johannessen SI, Perucca E (2015)
   Availability of antiepileptic drugs across Europe
   Epilepsia, 56 (12), e191-7
   DOI 10.1111/epi.13210, PubMed 26477534
2. Bakke SS, Feng YZ, Nikolić N, Kase ET, Moro C, Stensrud C, Damlien L, Ludahl MO, Sandbu R, Solheim BM, Rustan AC, Hjelmesæth J, Thoresen GH, Aas V (2015)
   Myotubes from severely obese type 2 diabetic subjects accumulate less lipids and show higher lipolytic rate than myotubes from severely obese non-diabetic subjects
   PLoS One, 10 (3), e0119556
   DOI 10.1371/journal.pone.0119556, PubMed 25790476
3. Beiske GA, Holmøy T, Beiske AG, Johannessen SI, Johannessen Landmark C (2015)
   Antiepileptic and Antidepressive Polypharmacy in Patients with Multiple Sclerosis
   Mult Scler Int, 2015, 317859
   DOI 10.1155/2015/317859, PubMed 26221541
4. Bergan S, Bremer S, Vethe NT (2015)
   Drug target molecules to guide immunosuppression
   Clin Biochem, 49 (4-5), 411-8
   DOI 10.1016/j.clinbiochem.2015.10.001, PubMed 26453533
5. Bernard JP, Khiabani HZ, Hilberg T, Karinen R, Slørdal L, Waal H, Mørland J (2015)
   Characteristics of methadone-related fatalities in Norway
   J Forensic Leg Med, 36, 114-20
   DOI 10.1016/j.jflm.2015.09.011, PubMed 26439870
6. Bialer M, Johannessen SI, Levy RH, Perucca E, Tomson T, White HS (2015)
   Progress report on new antiepileptic drugs: A summary of the Twelfth Eilat Conference (EILAT XII)
   Epilepsy Res, 111, 85-141
   DOI 10.1016/j.eplepsyres.2015.01.001, PubMed 25769377
7. Bjørner T, Anwar T, Brede WR, Hemmersbach P, Slørdal L (2015)
   [A man with a changed appearance]
   Tidsskr Nor Laegeforen, 135 (3), 243-5
   DOI 10.4045/tidsskr.14.0886, PubMed 25668542
8. Bremer S, Fløisand Y, Brinch L, Gedde-Dahl T, Bergan S (2015)
   Glutathione Transferase Gene Variants Influence Busulfan Pharmacokinetics and Outcome After Myeloablative Conditioning
   Ther Drug Monit, 37 (4), 493-500
   DOI 10.1097/FTD.0000000000000180, PubMed 25565670
9. Cehajic I, Bergan S, Bjordal K (2015)
   Pharmacist assessment of drug-related problems on an oncology ward
   Eur. J. Hosp. Pharm., 22 (4), 194-197
   DOI 10.1136/ejhpharm-2014-000510
10. de Graav GN, Bergan S, Baan CC, Weimar W, van Gelder T, Hesselink DA (2015)
    Therapeutic Drug Monitoring of Belatacept in Kidney Transplantation
    Ther Drug Monit, 37 (5), 560-7
    DOI 10.1097/FTD.0000000000000179, PubMed 25551406
11. Fagermoen E, Sulheim D, Winger A, Andersen AM, Gjerstad J, Godang K, Rowe PC, Saul JP, Skovlund E, Wyller VB (2015)
    Effects of low-dose clonidine on cardiovascular and autonomic variables in adolescents with chronic fatigue: a randomized controlled trial
    BMC Pediatr, 15, 117
    DOI 10.1186/s12887-015-0428-2, PubMed 26357864
12. Feng YZ, Nikolić N, Bakke SS, Kase ET, Guderud K, Hjelmesæth J, Aas V, Rustan AC, Thoresen GH (2015)
    Myotubes from lean and severely obese subjects with and without type 2 diabetes respond differently to an in vitro model of exercise
    Am J Physiol Cell Physiol, 308 (7), C548-56
    DOI 10.1152/ajpcell.00314.2014, PubMed 25608533
13. Hjelmeland K, Gustavsen I, Bernard JP, Mørland J (2015)
    Can a simple clinical test detect impairment of zopiclone and alcohol? - A randomized controlled trial
    Forensic Sci Int, 248, 129-33
    DOI 10.1016/j.forsciint.2014.12.028, PubMed 25617762
14. Hovda KE, Gadeholt G, Evtodienko V, Jacobsen D (2015)
    A novel bedside diagnostic test for methanol poisoning using dry chemistry for formate
    Scand J Clin Lab Invest, 75 (7), 610-4
    DOI 10.3109/00365513.2015.1066847, PubMed 26203958
15. Hullstein IR, Malerod-Fjeld H, Dehnes Y, Hemmersbach P (2015)
    Black market products confiscated in Norway 2011-2014 compared to analytical findings in urine samples
    Drug Test Anal, 7 (11-12), 1025-9
    DOI 10.1002/dta.1900, PubMed 26607218
16. Haase CB, Backer V, Kalsen A, Rzeppa S, Hemmersbach P, Hostrup M (2015)
    The influence of exercise and dehydration on the urine concentrations of salbutamol after inhaled administration of 1600 µg salbutamol as a single dose in relation to doping analysis
    Drug Test Anal, 8 (7), 613-20
    DOI 10.1002/dta.1828, PubMed 26044066
17. Impellizzeri AA, Pappalardo M, Basile L, Manfra O, Andressen KW, Krobert KA, Messina A, Levy FO, Guccione S (2015)
    Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis
    Front Behav Neurosci, 9, 92
    DOI 10.3389/fnbeh.2015.00092, PubMed 26005408
18. Jabeen S, Holmboe L, Alnæs GI, Andersen AM, Hall KS, Kristensen VN (2015)
    Impact of genetic variants of RFC1, DHFR and MTHFR in osteosarcoma patients treated with high-dose methotrexate
    Pharmacogenomics J, 15 (5), 385-90
    DOI 10.1038/tpj.2015.11, PubMed 25778468
19. Johannessen Landmark C, Beiske G, Baftiu A, Burns ML, Johannessen SI (2015)
    Experience from therapeutic drug monitoring and gender aspects of gabapentin and pregabalin in clinical practice
    Seizure, 28, 88-91
    DOI 10.1016/j.seizure.2015.02.017, PubMed 25758302
20. Johannessen Landmark C, I Johannessen S (2015)
    Pharmacotherapy in epilepsy - does gender affect safety?
    Expert Opin Drug Saf, 15 (1), 1-4
    DOI 10.1517/14740338.2016.1117606, PubMed 26650146
21. Karlsen Bjånes T, Mjåset Hjertø E, Lønne L, Aronsen L, Andsnes Berg J, Bergan S, Otto Berg-Hansen G, Bernard JP, Larsen Burns M, Toralf Fosen J, Frost J, Hilberg T, Krabseth HM, Kvan E, Narum S, Austgulen Westin A (2015)
    Pharmacology Portal: An Open Database for Clinical Pharmacologic Laboratory Services
    Clin Ther, 38 (1), 222-6
    DOI 10.1016/j.clinthera.2015.10.015, PubMed 26546404
22. Kase ET, Feng YZ, Badin PM, Bakke SS, Laurens C, Coue M, Langin D, Gaster M, Thoresen GH, Rustan AC, Moro C (2015)
    Primary defects in lipolysis and insulin action in skeletal muscle cells from type 2 diabetic individuals
    Biochim Biophys Acta, 1851 (9), 1194-201
    DOI 10.1016/j.bbalip.2015.03.005, PubMed 25819461
23. Kaupang Å, Paulsen SM, Steindal CC, Ravna AW, Sylte I, Halvorsen TG, Thoresen GH, Hansen TV (2015)
    Synthesis, biological evaluation and molecular modeling studies of the PPARβ/δ antagonist CC618
    Eur J Med Chem, 94, 229-36
    DOI 10.1016/j.ejmech.2015.03.006, PubMed 25768705
24. Kloster-Jensen K, Vethe NT, Bremer S, Abadpour S, Korsgren O, Foss A, Bergan S, Scholz H (2015)
    Intracellular sirolimus concentration is reduced by tacrolimus in human pancreatic islets in vitro
    Transpl Int, 28 (10), 1152-61
    DOI 10.1111/tri.12617, PubMed 26046470
25. Kong XY, Kase ET, Herskedal A, Schjalm C, Damme M, Nesset CK, Thoresen GH, Rustan AC, Eskild W (2015)
    Lack of the Lysosomal Membrane Protein, GLMP, in Mice Results in Metabolic Dysregulation in Liver
    PLoS One, 10 (6), e0129402
    DOI 10.1371/journal.pone.0129402, PubMed 26047317
26. Kringen MK (2015)
    Analysis of Copy Number Variation by Pyrosequencing® Using Paralogous Sequences
    Methods Mol Biol, 1315, 115-21
    DOI 10.1007/978-1-4939-2715-9_9, PubMed 26103895
27. Kringen MK, Stormo C, Berg JP, Terry SF, Vocke CM, Rizvi S, Hendig D, Piehler AP (2015)
    Copy number variation in the ATP-binding cassette transporter ABCC6 gene and ABCC6 pseudogenes in patients with pseudoxanthoma elasticum
    Mol Genet Genomic Med, 3 (3), 233-7
    DOI 10.1002/mgg3.137, PubMed 26029710
28. Manfra O, Van Craenenbroeck K, Skieterska K, Frimurer T, Schwartz TW, Levy FO, Andressen KW (2015)
    Downregulation of 5-HT7 Serotonin Receptors by the Atypical Antipsychotics Clozapine and Olanzapine. Role of Motifs in the C-Terminal Domain and Interaction with GASP-1
    ACS Chem Neurosci, 6 (7), 1206-18
    DOI 10.1021/cn500339p, PubMed 25706089
29. Nordal K, Øiestad EL, Enger A, Christophersen AS, Vindenes V (2015)
    Detection Times of Diazepam, Clonazepam, and Alprazolam in Oral Fluid Collected From Patients Admitted to Detoxification, After High and Repeated Drug Intake
    Ther Drug Monit, 37 (4), 451-60
    DOI 10.1097/FTD.0000000000000174, PubMed 25549207
30. Olberg DE, Hausner SH, Bauer N, Klaveness J, Indrevoll B, Andressen KW, Dahl M, Levy FO, Sutcliffe JL, Haraldsen I (2015)
    Radiosynthesis of high affinity fluorine-18 labeled GnRH peptide analogues: in vitro studies and in vivo assessment of brain uptake in rats
    MedChemComm, 6 (4), 708-714
    DOI 10.1039/c4md00486h
31. Opdal MS, Arnesen M, Müller LD, Hullstein I, Sayed K, Brørs O, Kringen M, Sagedal S, Gjesdal K, Krajci P (2015)
    Effects of Hemodialysis on Methadone Pharmacokinetics and QTc
    Clin Ther, 37 (7), 1594-9
    DOI 10.1016/j.clinthera.2015.04.009, PubMed 25963997
32. Reiter L, Westergren T (2015)
    Emergency contraception in overweight - to trust?
    Tidsskr. Nor. Laegeforen., 135 (18), 1629-1630
33. Robertsen I, Vethe NT, Midtvedt K, Falck P, Christensen H, Åsberg A (2015)
    Closer to the Site of Action: Everolimus Concentrations in Peripheral Blood Mononuclear Cells Correlate Well With Whole Blood Concentrations
    Ther Drug Monit, 37 (5), 675-80
    DOI 10.1097/FTD.0000000000000185, PubMed 25565673
34. Robertsen I, Åsberg A, Ingerø AO, Vethe NT, Bremer S, Bergan S, Midtvedt K (2015)
    Use of generic tacrolimus in elderly renal transplant recipients: precaution is needed
    Transplantation, 99 (3), 528-32
    DOI 10.1097/TP.0000000000000384, PubMed 25148382
35. Rogeberg M, Almdahl IS, Wettergreen M, Nilsson LN, Fladby T (2015)
    Isobaric Quantification of Cerebrospinal Fluid Amyloid-β Peptides in Alzheimer's Disease: C-Terminal Truncation Relates to Early Measures of Neurodegeneration
    J Proteome Res, 14 (11), 4834-43
    DOI 10.1021/acs.jproteome.5b00668, PubMed 26452689
36. Rogeberg M, Wettergreen M, Nilsson LN, Fladby T (2015)
    Identification of amyloid beta mid-domain fragments in human cerebrospinal fluid
    Biochimie, 113, 86-92
    DOI 10.1016/j.biochi.2015.03.022, PubMed 25866191
37. Rzeppa S, Heinrich G, Hemmersbach P (2015)
    Analysis of anabolic androgenic steroids as sulfate conjugates using high performance liquid chromatography coupled to tandem mass spectrometry
    Drug Test Anal, 7 (11-12), 1030-9
    DOI 10.1002/dta.1895, PubMed 26472592
38. Salvador CL, Tøndel C, Mørkrid L, Bjerre A, Brun A, Bolann B, Brackman D, Bergan S (2015)
    Glomerular filtration rate measured by iohexol clearance: A comparison of venous samples and capillary blood spots
    Scand J Clin Lab Invest, 75 (8), 710-6
    DOI 10.3109/00365513.2015.1091091, PubMed 26426851
39. Sollid LM, Iversen R, Steinsbø Ø, Qiao SW, Bergseng E, Dørum S, du Pré MF, Stamnaes J, Christophersen A, Cardoso I, Hnida K, Chen X, Snir O, Lundin KEA (2015)
    Small bowel, celiac disease and adaptive immunity
    Dig Dis, 33 (2), 115-121
    DOI 10.1159/000369512, PubMed 25925911
40. Størset E, Åsberg A, Skauby M, Neely M, Bergan S, Bremer S, Midtvedt K (2015)
    Improved Tacrolimus Target Concentration Achievement Using Computerized Dosing in Renal Transplant Recipients--A Prospective, Randomized Study
    Transplantation, 99 (10), 2158-66
    DOI 10.1097/TP.0000000000000708, PubMed 25886918
41. Tveteraas IH, Aasrum M, Brusevold IJ, Ødegård J, Christoffersen T, Sandnes D (2015)
    Lysophosphatidic acid induces both EGFR-dependent and EGFR-independent effects on DNA synthesis and migration in pancreatic and colorectal carcinoma cells
    Tumour Biol, 37 (2), 2519-26
    DOI 10.1007/s13277-015-4010-1, PubMed 26386720
42. Ørstavik Ø, Manfra O, Andressen KW, Andersen GØ, Skomedal T, Osnes JB, Levy FO, Krobert KA (2015)
    The inotropic effect of the active metabolite of levosimendan, OR-1896, is mediated through inhibition of PDE3 in rat ventricular myocardium
    PLoS One, 10 (3), e0115547
    DOI 10.1371/journal.pone.0115547, PubMed 25738589
43. Aasrum M, Tjomsland V, Thoresen GH, De Angelis PM, Christoffersen T, Brusevold IJ (2015)
    PI3K is required for both basal and LPA-induced DNA synthesis in oral carcinoma cells
    J Oral Pathol Med, 45 (6), 425-32
    DOI 10.1111/jop.12384, PubMed 26602326
44. Aasrum M, Ødegård J, Thoresen GH, Brusevold IJ, Sandnes DL, Christoffersen T (2015)
    Gab1 amplifies signaling in response to low-intensity stimulation by HGF
    Cell Biol Int, 39 (10), 1177-84
    DOI 10.1002/cbin.10511, PubMed 26146811