Oslo Clinical Dementia Research group
Group leader
The Oslo Clinical Dementia Research group has a broad approach to dementia research. Our overarching aim of research is to improve diagnostic methods for dementia disorders and ultimately provide better treatment and care for patients with dementia. To achieve this, we study:
- pathophysiological mechanisms of dementia disorders
- new and accurate clinical, digital and biological diagnostic markers of specific dementia disorders, especially Alzheimer’s disease
- artificial intelligence (AI) tools to improve diagnosis of dementia disorders in clinical practice
- the influence of comorbidities, genetic and epigenetic mechanisms, inflammatory processes, biological sex and sex-specific risk factors and stress on dementia disorders
- interventions that could prevent or slow down the dementia process, such as advanced cognitive training.
About us
Our group consists of several postdocs and PhD students with different background in dementia research. A large part of our research is performed at the memory clinic, Ullevaal, with patients included in the Norwegian Registry of Persons Assessed for Cognitive Symptoms in Specialist Health Care Services (NorCog). The NorCog registry is a national dementia quality register with an associated biobank, which gives us the opportunity to collect data for epidemiological and clinical research. The patients included from the memory clinic at Ullevaal are diverse and enable the study of disease markers for patients at different stages of cognitive impairment (subjective cognitive impairment, mild cognitive impairment (MCI) and dementia) and with different dementia and non-dementia disorders (e.g. Alzheimer’s disease, frontotemporal dementia or depression) The group has an extensive collaboration with the Norwegian National Centre for Ageing and Health (Ageing and Health). We participate in the Norwegian cognitive impairment after stroke study (Nor-COAST) and form the clinical arm of the K.G. Jebsen Centre for Brain Fluid Research.
Further, we participate in European research projects such as IHI-PROMINENT and in the European Disease Consortium (EADC).
Long-term goals
Currently, our major research focuses are diagnostic and prognostic biomarker studies, the exploration of risk factors for progression in dementia, interventions to prevent and delay the dementia progress and validation of AI diagnostic tools to improve diagnostic flow. We also collaborate (inter)nationally to explore whether new clinical, digital and biological biomarkers can be applied to our memory clinic cohort, leading to a more timely diagnosis.
View Ongoing projects