CIRRO

Einar Lindalen

Consultant orthopaedic surgeon; MD, PhD
23 22 50 00

Einar Lindalen, MD, Orthopaedic Surgeon, Lovisenberg Diaconal Hospital ,Oslo, Norway.

Performing orthopaedic surgery with special interest in knee, hip and shoulder surgery.

Project: ”Reverse hybrid total hip replacement: Wear, fixation and bone remodelling”

Description:
Reverse hybrid total hip replacement uses a cemented all polyethylene acetabular cup in combination with an uncemented femoral stem.

Background:
There has been an increasing use of reverse hybrid total hip replacement in Norway and Sweden during the last decade. Despite increasing use of this method there has been very little documentation of results.

Methods:
Register studies
Prospective randomized clinical studies
Radiostereometry
Dual energy x-ray absorptiometry
Conventional X-ray
Clinical follow up of patients

Purpose:
Main purpose is to document the current method and compare it to cemented implants

Aim:
-Study the reverse hybrid and compare it to the conventional cemented total hip replacement
-Investigate uncemented total hip replacement using a second generation highly cross-linked polyethylene.
-Our focus is on the wear of the polyethylene, fixation of the acetabulum and femoral stem and remodelling of bone around these
-By documentation of different methods our aim of research is to reduce revision surgery

Planned studies:

1 Measure wear, migration of components and bone mineral density in femur and acetabulum, in reverse hybrid THR and cemented THR. Randomized prospective study.

2 Evaluate medium-term follow up of reverse THR from the Norwegian Arthroplasty Register.

3 Evaluate wear and bone mineral density using 3. generation highly cross-linked polyethylene with 32 or 36 mm femoral head of ceramics. Prospective randomized study.

4 Method for wear measurements– study of methods.

5 NARA study on reverse hybrid THR. Study accepted by the NARA administration.

Supervisors:
Stephan M. Röhrl, MD, PhD, Orthopaedic Surgeon
Lars Nordsletten, MD, PhD, Professor, Orthopaedic Surgeon

Publications 2021

Leta TH, Gjertsen JE, Dale H, Hallan G, Lygre SHL, Fenstad AM, Dyrhovden GS, Westberg M, Wik TS, Jakobsen RB, Aamodt A, Röhrl SM, Gøthesen ØJ, Lindalen E, Heir S, Ludvigsen J, Bruun T, Hansen AK, Aune KEM, Warholm M, Skjetne JP, Badawy M, Høvding P, Husby OS, Karlsen ØE et al. (2021)
Antibiotic-Loaded Bone Cement in Prevention of Periprosthetic Joint Infections in Primary Total Knee Arthroplasty: A Register-based Multicentre Randomised Controlled Non-inferiority Trial (ALBA trial)
BMJ Open, 11 (1), e041096
DOI 10.1136/bmjopen-2020-041096, PubMed 33509845

Publications 2020

Gautvik KM, Günther CC, Prijatelj V, Medina-Gomez C, Shevroja E, Rad LH, Yazdani M, Lindalen E, Valland H, Gautvik VT, Olstad OK, Holden M, Rivadeneira F, Utheim TP, Reppe S (2020)
Distinct Subsets of Noncoding RNAs Are Strongly Associated With BMD and Fracture, Studied in Weight-Bearing and Non-Weight-Bearing Human Bone
J Bone Miner Res, 35 (6), 1065-1076
DOI 10.1002/jbmr.3974, PubMed 32017184

Publications 2018

Lindalen E, Thoen PS, Nordsletten L, Høvik Ø, Röhrl SM (2018)
Low wear rate at 6-year follow-up of vitamin E-infused cross-linked polyethylene: a randomised trial using 32- and 36-mm heads
Hip Int, 29 (4), 355-362
DOI 10.1177/1120700018798790, PubMed 30227721

Publications 2015

Lindalen E, Nordsletten L, Høvik Ø, Röhrl SM (2015)
E-vitamin infused highly cross-linked polyethylene: RSA results from a randomised controlled trial using 32 mm and 36 mm ceramic heads
Hip Int, 25 (1), 50-5
DOI 10.5301/hipint.5000195, PubMed 25633755

Publications 2012

Lindalen E, Dahl J, Nordsletten L, Snorrason F, Høvik Ø, Röhrl S (2012)
Reverse hybrid and cemented hip replacement compared using radiostereometry and dual-energy X-ray absorptiometry: 43 hips followed for 2 years in a prospective trial
Acta Orthop, 83 (6), 592-8
DOI 10.3109/17453674.2012.742393, PubMed 23116437

Publications 2011

Lindalen E, Havelin LI, Nordsletten L, Dybvik E, Fenstad AM, Hallan G, Furnes O, Høvik O, Röhrl SM (2011)
Is reverse hybrid hip replacement the solution?
Acta Orthop, 82 (6), 639-45
DOI 10.3109/17453674.2011.623569, PubMed 21999624

Lindalen E, Nordsletten L, Röhrl SM (2011)
Segment choice and cup stability influence wear measurements using radiostereometric analysis: a radiostereometric study comparing wear measured by markers in the polyethylene with markers in the periacetabular bone
Clin Biomech (Bristol, Avon), 27 (5), 511-4
DOI 10.1016/j.clinbiomech.2011.11.009, PubMed 22197589