Tor Paaske Utheim
Position: Group leader
Phone: +47 93085870
Email:
 

Author network for Tor Paaske Utheim by COREMINE medical


Publications 2017

Aqrawi LA, Galtung HK, Vestad B, Øvstebø R, Thiede B, Rusthen S, Young A, Guerreiro EM, Utheim TP, Chen X, Utheim ØA, Palm Ø, Jensen JL (2017)
Identification of potential saliva and tear biomarkers in primary Sjögren's syndrome, utilising the extraction of extracellular vesicles and proteomics analysis
Arthritis Res Ther, 19 (1), 14
PubMed 28122643

Chen X, Stojanovic A, Xu Y, Zhou W, Raeder S, Enayati S, Utheim TP (2017)
Medium- to Long-Term Results of Corneal Cross-Linking for Keratoconus Using Phototherapeutic Keratectomy for Epithelial Removal and Partial Stromal Ablation
J Refract Surg, 33 (7), 488-495
PubMed 28681909

Chen X, Utheim ØA, Xiao J, Adil MY, Stojanovic A, Tashbayev B, Jensen JL, Utheim TP (2017)
Meibomian gland features in a Norwegian cohort of patients with primary Sjögren´s syndrome
PLoS One, 12 (9), e0184284
PubMed 28886085

Fostad IG, Eidet JR, Lagali NS, Dartt DA, Ræder S, Messelt EB, Utheim TP (2017)
Identification of Objective Morphometric Markers of Xerostomia in the Oral Mucosa Epithelium with In Vivo Confocal Microscopy
Microsc Microanal, 23 (1), 88-96
PubMed 28162126

Islam R, Eidet JR, Badian RA, Lippestad M, Messelt E, Griffith M, Dartt DA, Utheim TP (2017)
Tissue Harvesting Site and Culture Medium Affect Attachment, Growth, and Phenotype of Ex Vivo Expanded Oral Mucosal Epithelial Cells
Sci Rep, 7 (1), 674
PubMed 28386069

Jackson CJ, Reppe S, Eidet JR, Eide L, Tønseth KA, Bergersen LH, Dartt DA, Griffith M, Utheim TP (2017)
Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets
Sci Rep, 7 (1), 8206
PubMed 28811665

Jackson CJ, Tønseth KA, Utheim TP (2017)
Cultured epidermal stem cells in regenerative medicine
Stem Cell Res Ther, 8 (1), 155
PubMed 28676094

Landsend ES, Utheim ØA, Pedersen HR, Lagali N, Baraas RC, Utheim TP (2017)
The Genetics of Congenital Aniridia - A Guide for the Ophthalmologist
Surv Ophthalmol (in press)
PubMed 28923585

Lippestad M, Hodges RR, Utheim TP, Serhan CN, Dartt DA (2017)
Resolvin D1 Increases Mucin Secretion in Cultured Rat Conjunctival Goblet Cells via Multiple Signaling Pathways
Invest Ophthalmol Vis Sci, 58 (11), 4530-4544
PubMed 28892824

Tashbayev B, Rusthen S, Young A, Herlofson BB, Hove LH, Singh PB, Rykke M, Aqrawi LA, Chen X, Utheim ØA, Utheim TP, Palm Ø, Jensen JL (2017)
Interdisciplinary, Comprehensive Oral and Ocular Evaluation of Patients with Primary Sjögren's Syndrome
Sci Rep, 7 (1), 10761
PubMed 28883442

Publications 2016

Chen X, Stojanovic A, Simonsen D, Wang X, Liu Y, Utheim TP (2016)
Topography-Guided Transepithelial Surface Ablation in the Treatment of Moderate to High Astigmatism
J Refract Surg, 32 (6), 418-25
PubMed 27304606

Chen X, Stojanovic A, Wang X, Liang J, Hu D, Utheim TP (2016)
Epithelial Thickness Profile Change After Combined Topography-Guided Transepithelial Photorefractive Keratectomy and Corneal Cross-linking in Treatment of Keratoconus
J Refract Surg, 32 (9), 626-34
PubMed 27598733

Eidet JR, Reppe S, Pasovic L, Olstad OK, Lyberg T, Khan AZ, Fostad IG, Chen DF, Utheim TP (2016)
The Silk-protein Sericin Induces Rapid Melanization of Cultured Primary Human Retinal Pigment Epithelial Cells by Activating the NF-κB Pathway
Sci Rep, 6, 22671
PubMed 26940175

Fostad IG, Eidet JR, Utheim TP, Ræder S, Lagali NS, Messelt EB, Dartt DA (2016)
Dry Eye Disease Patients with Xerostomia Report Higher Symptom Load and Have Poorer Meibum Expressibility
PLoS One, 11 (5), e0155214
PubMed 27148875

He M, Storr-Paulsen T, Wang AL, Ghezzi CE, Wang S, Fullana M, Karamichos D, Utheim TP, Islam R, Griffith M, Islam MM, Hodges RR, Wnek GE, Kaplan DL, Dartt DA (2016)
Artificial Polymeric Scaffolds as Extracellular Matrix Substitutes for Autologous Conjunctival Goblet Cell Expansion
Invest Ophthalmol Vis Sci, 57 (14), 6134-6146
PubMed 27832279

Hua Y, Zhang X, Utheim TP, Huang J, Pan C, Tan W, Wang Q (2016)
Evaluation of Equivalent Keratometry Readings Obtained by Pentacam HR (High Resolution)
PLoS One, 11 (3), e0150121
PubMed 26950834

Khan AZ, Utheim TP, Jackson CJ, Reppe S, Lyberg T, Eidet JR (2016)
Nucleus Morphometry in Cultured Epithelial Cells Correlates with Phenotype
Microsc Microanal, 22 (3), 612-20
PubMed 27329312

Khuu C, Nirvani M, Utheim TP, Sehic A (2016)
MicroRNAs: Modulators of Tooth Development
Microrna, 5 (2), 132-139
PubMed 27397033

Khuu C, Utheim TP, Sehic A (2016)
The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25
Scientifica (Cairo), 2016, 1379643
PubMed 27127675

Kolko M, Vosborg F, Henriksen UL, Hasan-Olive MM, Diget EH, Vohra R, Gurubaran IR, Gjedde A, Mariga ST, Skytt DM, Utheim TP, Storm-Mathisen J, Bergersen LH (2016)
Erratum to: Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease
Neurochem Res, 41 (6), 1237
PubMed 27113043

Nirvani M, Khuu C, Utheim TP, Hollingen HS, Amundsen SF, Sand LP, Sehic A (2016)
Circadian rhythms and gene expression during mouse molar tooth development
Acta Odontol Scand, 75 (2), 144-153
PubMed 28030993

Parissi M, Randjelovic S, Poletti E, Guimarães P, Ruggeri A, Fragkiskou S, Wihlmark TB, Utheim TP, Lagali N (2016)
Corneal Nerve Regeneration After Collagen Cross-Linking Treatment of Keratoconus: A 5-Year Longitudinal Study
JAMA Ophthalmol, 134 (1), 70-8
PubMed 26562763

Pasovic L, Eidet JR, Olstad OK, Chen DF, Lyberg T, Utheim TP (2016)
Impact of Storage Temperature on the Expression of Cell Survival Genes in Cultured ARPE-19 Cells
Curr Eye Res, 42 (1), 134-144
PubMed 27259952

Salvanos P, Moe MC, Utheim TP, Bragadóttir R, Kerty E (2016)
ULTRA-WIDE-FIELD FUNDUS IMAGING IN THE DIAGNOSIS AND FOLLOW-UP OF SUSAC SYNDROME
Retin Cases Brief Rep (in press)
PubMed 27828899

Sehic A, Guo S, Cho KS, Corraya RM, Chen DF, Utheim TP (2016)
Electrical Stimulation as a Means for Improving Vision
Am J Pathol, 186 (11), 2783-2797
PubMed 27643530

Sehic A, Tulek A, Khuu C, Nirvani M, Sand LP, Utheim TP (2016)
Regulatory roles of microRNAs in human dental tissues
Gene, 596, 9-18
PubMed 27725267

Shatos MA, Hodges RR, Morinaga M, McNay DE, Islam R, Bhattacharya S, Li D, Turpie B, Makarenkova HP, Masli S, Utheim TP, Dartt DA (2016)
Alteration in cellular turnover and progenitor cell population in lacrimal glands from thrombospondin 1(-/-) mice, a model of dry eye
Exp Eye Res, 153, 27-41
PubMed 27697548

Utheim TP, Islam R, Fostad IG, Eidet JR, Sehic A, Olstad OK, Dartt DA, Messelt EB, Griffith M, Pasovic L (2016)
Storage Temperature Alters the Expression of Differentiation-Related Genes in Cultured Oral Keratinocytes
PLoS One, 11 (3), e0152526
PubMed 27023475

Utheim TP, Salvanos P, Utheim ØA, Ræder S, Pasovic L, Olstad OK, de la Paz MF, Sehic A (2016)
Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS
J Funct Biomater, 7 (1)
PubMed 26901233

Utheim TP, Utheim ØA, Khan QE, Sehic A (2016)
Culture of Oral Mucosal Epithelial Cells for the Purpose of Treating Limbal Stem Cell Deficiency
J Funct Biomater, 7 (1)
PubMed 26938569

Zhou W, Stojanovic A, Utheim TP (2016)
Assessment of refractive astigmatism and simulated therapeutic refractive surgery strategies in coma-like-aberrations-dominant corneal optics
Eye Vis (Lond), 3, 13
PubMed 27175371

Publications 2015

Björkblom B, Eidet JR, Utheim TP, Ulltveit-Moe HF, Raeder S (2015)
Xenobiotic- and Serum-Free Culture of Oral Mucosal Epithelial Cells on Contact Lenses
Curr Eye Res, 41 (1), 20-7
PubMed 25658020

Chen X, Stojanovic A, Eidet JR, Utheim TP (2015)
Corneal collagen cross-linking (CXL) in thin corneas
Eye Vis (Lond), 2, 15
PubMed 26605368

Chen X, Stojanovic A, Liu Y, Chen Y, Zhou Y, Utheim TP (2015)
Postoperative Changes in Corneal Epithelial and Stromal Thickness Profiles After Photorefractive Keratectomy in Treatment of Myopia
J Refract Surg, 31 (7), 446-53
PubMed 26186563

Eidet JR, Dartt DA, Utheim TP (2015)
Concise Review: Comparison of Culture Membranes Used for Tissue Engineered Conjunctival Epithelial Equivalents
J Funct Biomater, 6 (4), 1064-84
PubMed 26690486

Hua Y, Stojanovic A, Utheim TP, Chen X, Ræder S, Huang J, Wang Q (2015)
Keratometric index obtained by Fourier-domain optical coherence tomography
PLoS One, 10 (4), e0122441
PubMed 25886489

Islam R, Jackson C, Eidet JR, Messelt EB, Corraya RM, Lyberg T, Griffith M, Dartt DA, Utheim TP (2015)
Effect of Storage Temperature on Structure and Function of Cultured Human Oral Keratinocytes
PLoS One, 10 (6), e0128306
PubMed 26052937

Jackson C, Eidet JR, Reppe S, Aass HC, Tønseth KA, Roald B, Lyberg T, Utheim TP (2015)
Effect of Storage Temperature on the Phenotype of Cultured Epidermal Cells Stored in Xenobiotic-Free Medium
Curr Eye Res, 41 (6), 757-68
PubMed 26398483

Kolko M, Vosborg F, Henriksen UL, Hasan-Olive MM, Diget EH, Vohra R, Gurubaran IR, Gjedde A, Mariga ST, Skytt DM, Utheim TP, Storm-Mathisen J, Bergersen LH (2015)
Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease
Neurochem Res, 41 (6), 1229-36
PubMed 26677077

Lagali N, Poletti E, Patel DV, McGhee CN, Hamrah P, Kheirkhah A, Tavakoli M, Petropoulos IN, Malik RA, Utheim TP, Zhivov A, Stachs O, Falke K, Peschel S, Guthoff R, Chao C, Golebiowski B, Stapleton F, Ruggeri A (2015)
Focused Tortuosity Definitions Based on Expert Clinical Assessment of Corneal Subbasal Nerves
Invest Ophthalmol Vis Sci, 56 (9), 5102-9
PubMed 26241397

Navaratnam J, Utheim TP, Rajasekhar VK, Shahdadfar A (2015)
Substrates for Expansion of Corneal Endothelial Cells towards Bioengineering of Human Corneal Endothelium
J Funct Biomater, 6 (3), 917-45
PubMed 26378588

Pasovic L, Eidet JR, Brusletto BS, Lyberg T, Utheim TP (2015)
Effect of Storage Temperature on Key Functions of Cultured Retinal Pigment Epithelial Cells
J Ophthalmol, 2015, 263756
PubMed 26448872

Salvanos P, Utheim TP, Moe MC, Eide N, Bragadόttir R (2015)
Autofluorescence imaging in the differential diagnosis of optic disc melanocytoma
Acta Ophthalmol, 93 (5), 476-80
PubMed 25923254

Sehic A, Utheim ØA, Ommundsen K, Utheim TP (2015)
Pre-Clinical Cell-Based Therapy for Limbal Stem Cell Deficiency
J Funct Biomater, 6 (3), 863-88
PubMed 26343740

Utheim O, Islam R, Lyberg T, Roald B, Eidet JR, de la Paz MF, Dartt DA, Raeder S, Utheim TP (2015)
Serum-free and xenobiotic-free preservation of cultured human limbal epithelial cells
PLoS One, 10 (3), e0118517
PubMed 25734654

Utheim TP (2015)
Concise review: transplantation of cultured oral mucosal epithelial cells for treating limbal stem cell deficiency-current status and future perspectives
Stem Cells, 33 (6), 1685-95
PubMed 25786664

Publications 2014

Chen X, Stojanovic A, Hua Y, Eidet JR, Hu D, Wang J, Utheim TP (2014)
Reliability of corneal dynamic scheimpflug analyser measurements in virgin and post-PRK eyes
PLoS One, 9 (10), e109577
PubMed 25302580

Eidet JR, Pasovic L, Maria R, Jackson CJ, Utheim TP (2014)
Objective assessment of changes in nuclear morphology and cell distribution following induction of apoptosis
Diagn Pathol, 9, 92
PubMed 24885713

Eidet JR, Utheim ØA, Islam R, Lyberg T, Messelt EB, Dartt DA, Utheim TP (2014)
The impact of storage temperature on the morphology, viability, cell number and metabolism of cultured human conjunctival epithelium
Curr Eye Res, 40 (1), 30-9
PubMed 24750037

Jackson C, Aabel P, Eidet JR, Messelt EB, Lyberg T, von Unge M, Utheim TP (2014)
Effect of storage temperature on cultured epidermal cell sheets stored in xenobiotic-free medium
PLoS One, 9 (8), e105808
PubMed 25170754

Pasovic L, Eidet JR, Lyberg T, Messelt EB, Aabel P, Utheim TP (2014)
Antioxidants Improve the Viability of Stored Adult Retinal Pigment Epithelial-19 Cultures
Ophthalmol Ther, 3 (1-2), 49-61
PubMed 25134496

Stojanovic A, Zhou W, Utheim TP (2014)
Corneal collagen cross-linking with and without epithelial removal: a contralateral study with 0.5% hypotonic riboflavin solution
Biomed Res Int, 2014, 619398
PubMed 25050368

Publications 2013

Edén U, Lagali N, Dellby A, Utheim TP, Riise R, Chen X, Fagerholm P (2013)
Cataract development in Norwegian patients with congenital aniridia
Acta Ophthalmol, 92 (2), e165-7
PubMed 23826968

Engelsvold DH, Utheim TP, Olstad OK, Gonzalez P, Eidet JR, Lyberg T, Trøseid AM, Dartt DA, Raeder S (2013)
miRNA and mRNA expression profiling identifies members of the miR-200 family as potential regulators of epithelial-mesenchymal transition in pterygium
Exp Eye Res, 115, 189-98
PubMed 23872359

Lagali N, Edén U, Utheim TP, Chen X, Riise R, Dellby A, Fagerholm P (2013)
In vivo morphology of the limbal palisades of vogt correlates with progressive stem cell deficiency in aniridia-related keratopathy
Invest Ophthalmol Vis Sci, 54 (8), 5333-42
PubMed 23860752

Liu Y, Yang X, Utheim TP, Guo C, Xiao M, Liu Y, Yin Z, Ma J (2013)
Correlation of cytokine levels and microglial cell infiltration during retinal degeneration in RCS rats
PLoS One, 8 (12), e82061
PubMed 24349184

Parissi M, Karanis G, Randjelovic S, Germundsson J, Poletti E, Ruggeri A, Utheim TP, Lagali N (2013)
Standardized baseline human corneal subbasal nerve density for clinical investigations with laser-scanning in vivo confocal microscopy
Invest Ophthalmol Vis Sci, 54 (10), 7091-102
PubMed 24084094

Pasovic L, Utheim TP, Maria R, Lyberg T, Messelt EB, Aabel P, Chen DF, Chen X, Eidet JR (2013)
Optimization of Storage Temperature for Cultured ARPE-19 Cells
J Ophthalmol, 2013, 216359
PubMed 24251032

Stojanovic A, Chen S, Chen X, Stojanovic F, Zhang J, Zhang T, Utheim TP (2013)
One-step transepithelial topography-guided ablation in the treatment of myopic astigmatism
PLoS One, 8 (6), e66618
PubMed 23799124

Utheim TP (2013)
Limbal epithelial cell therapy: past, present, and future
Methods Mol Biol, 1014, 3-43
PubMed 23690002

Utheim TP, Lyberg T, Ræder S (2013)
The culture of limbal epithelial cells
Methods Mol Biol, 1014, 103-29
PubMed 23690008

Publications 2012

Chen X, Stojanovic A, Stojanovic F, Eidet JR, Raeder S, Øritsland H, Utheim TP (2012)
Effect of limbal marking prior to laser ablation on the magnitude of cyclotorsional error
J Refract Surg, 28 (5), 358-62
PubMed 22421093

Eidet JR, Fostad IG, Shatos MA, Utheim TP, Utheim ØA, Raeder S, Dartt DA (2012)
Effect of biopsy location and size on proliferative capacity of ex vivo expanded conjunctival tissue
Invest Ophthalmol Vis Sci, 53 (6), 2897-903
PubMed 22491407

Fostad IG, Eidet JR, Shatos MA, Utheim TP, Utheim OA, Raeder S, Dartt DA (2012)
Biopsy harvesting site and distance from the explant affect conjunctival epithelial phenotype ex vivo
Exp Eye Res, 104, 15-25
PubMed 23022405

Stojanovic A, Chen X, Jin N, Zhang T, Stojanovic F, Raeder S, Utheim TP (2012)
Safety and efficacy of epithelium-on corneal collagen cross-linking using a multifactorial approach to achieve proper stromal riboflavin saturation
J Ophthalmol, 2012, 498435
PubMed 22900147

Publications 2011

Chen X, Stojanovic A, Zhou W, Utheim TP, Stojanovic F, Wang Q (2011)
Transepithelial, Topography-guided Ablation in the Treatment of Visual Disturbances in LASIK Flap or Interface Complications
J Refract Surg, 28 (2), 120-6
PubMed 21974725

Eidet JR, Utheim OA, Raeder S, Dartt DA, Lyberg T, Carreras E, Huynh TT, Messelt EB, Louch WE, Roald B, Utheim TP (2011)
Effects of serum-free storage on morphology, phenotype, and viability of ex vivo cultured human conjunctival epithelium
Exp Eye Res, 94 (1), 109-16
PubMed 22154551

Publications 2010

Raeder S, Utheim TP, Messelt E, Lyberg T (2010)
The impact of de-epithelialization of the amniotic membrane matrix on morphology of cultured human limbal epithelial cells subject to eye bank storage
Cornea, 29 (4), 439-45
PubMed 20164752

Publications 2009

Utheim TP, Raeder S, Olstad OK, Utheim ØA, de La Paz M, Cheng R, Huynh TT, Messelt E, Roald B, Lyberg T (2009)
Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions
Invest Ophthalmol Vis Sci, 50 (11), 5165-72
PubMed 19578011

Utheim TP, Raeder S, Utheim ØA, de la Paz M, Roald B, Lyberg T (2009)
Sterility control and long-term eye-bank storage of cultured human limbal epithelial cells for transplantation
Br J Ophthalmol, 93 (7), 980-3
PubMed 19211610

Publications 2008

Utheim ØA, Ritland JS, Utheim TP, Espeseth T, Lydersen S, Rootwelt H, Semb SO, Elsås T (2008)
Apolipoprotein E genotype and risk for development of cataract and age-related macular degeneration
Acta Ophthalmol, 86 (4), 401-3
PubMed 18498549

Publications 2007

Raeder S, Utheim TP, Utheim OA, Cai Y, Roald B, Lyberg T, Kjeldsen-Kragh J, Ramstad H, Messelt E, Nicolaissen B (2007)
Effect of limbal explant orientation on the histology, phenotype, ultrastructure and barrier function of cultured limbal epithelial cells
Acta Ophthalmol Scand, 85 (4), 377-86
PubMed 17263847

Raeder S, Utheim TP, Utheim OA, Nicolaissen B, Roald B, Cai Y, Haug K, Kvalheim A, Messelt EB, Drolsum L, Reed JC, Lyberg T (2007)
Effects of organ culture and Optisol-GS storage on structural integrity, phenotypes, and apoptosis in cultured corneal epithelium
Invest Ophthalmol Vis Sci, 48 (12), 5484-93
PubMed 18055796

Ritland JS, Utheim TP, Utheim OA, Espeseth T, Lydersen S, Semb SO, Rootwelt H, Elsås T (2007)
Effects of APOE and CHRNA4 genotypes on retinal nerve fibre layer thickness at the optic disc and on risk for developing exfoliation syndrome
Acta Ophthalmol Scand, 85 (3), 257-61
PubMed 17488453