Our aim is to identify the cellular origins of breast tumors and the mechanisms behind tumor initiation and further development into the heterogeneous molecular subtypes. We are particularly interested in DCIS and the transition to invasive carcinomas. Through an increased understanding of how tumors progress to more advances stages, improved strategies for early intervention and more precise treatment can be developed.
- Unraveling the ambiguous role of HER2 in DCIS and transition to invasive breast cancer
- Spatial heterogeneity and cell lineages in DCIS
- FGFR1 in luminal breast tumorigenesis
- Comparative Oncology: What can canine mammary gland tumorigenesis teach us about human breast cancer?
- Improved classification of Endometrial Cancer by integrated genomics