Publications by Mouldy Sioud

210 publications found

Publications 2024

  1. Sioud M, Juzeniene A, Sæbøe-Larssen S (2024)
    Exploring the Impact of mRNA Modifications on Translation Efficiency and Immune Tolerance to Self-Antigens
    Vaccines (Basel), 12 (6)
    DOI 10.3390/vaccines12060624, PubMed 38932353

Publications 2023

  1. Sioud M (2023)
    How the initial discovery of modified RNA enabled evasion of innate immune responses and facilitated the development of RNA therapeutics
    Scand J Immunol, 98 (1), e13282
    DOI 10.1111/sji.13282, PubMed 37132451
  2. Sioud M, Olberg A (2023)
    Antibody Surface Profiling Identifies Glycoforms in Multiple Myeloma as Targets for Immunotherapy: From Antibody Derivatives to Mimetic Peptides for Killing Tumor Cells
    Cancers (Basel), 15 (7)
    DOI 10.3390/cancers15071934, PubMed 37046595
  3. Sioud M, Zhang Q (2023)
    Precision Killing of M2 Macrophages with Phage-Displayed Peptide-Photosensitizer Conjugates
    Cancers (Basel), 15 (7)
    DOI 10.3390/cancers15072009, PubMed 37046671
  4. Zhang Q, Sioud M (2023)
    Tumor-Associated Macrophage Subsets: Shaping Polarization and Targeting
    Int J Mol Sci, 24 (8)
    DOI 10.3390/ijms24087493, PubMed 37108657

Publications 2022

  1. Zhang Q, Olberg A, Sioud M (2022)
    Structural Requirements for the Binding of a Peptide to Prohibitins on the Cell Surface of Monocytes/Macrophages
    Int J Mol Sci, 23 (8)
    DOI 10.3390/ijms23084282, PubMed 35457098

Publications 2021

  1. Sioud M (2021)
    RNA Interference: Story and Mechanisms
    Methods Mol Biol, 2282, 1-15
    DOI 10.1007/978-1-0716-1298-9_1, PubMed 33928566
  2. Sioud M (2021)
    Reducing the immunosuppressive tumor microenvironment enhances photoimmunotherapy efficacy
    EBioMedicine, 67, 103351
    DOI 10.1016/j.ebiom.2021.103351, PubMed 33965875
  3. Sioud M, Juzenas P, Zhang Q, Kleinauskas A, Peng Q (2021)
    Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Cell Monolayer and Multicellular Tumor Spheroid Models
    Cancers (Basel), 13 (13)
    DOI 10.3390/cancers13133356, PubMed 34283089
  4. Sioud M, Juzenas P, Zhang Q, Kleinauskas A, Peng Q (2021)
    Correction: Sioud et al. Evaluation of In Vitro Phototoxicity of a Minibody-IR700 Conjugate Using Monolayer and Multicellular Tumor Spheroid Models. Cancers 2021, 13, 3356
    Cancers (Basel), 13 (21)
    DOI 10.3390/cancers13215513, PubMed 34771754

Publications 2020

  1. Darvekar S, Juzenas P, Oksvold M, Kleinauskas A, Holien T, Christensen E, Stokke T, Sioud M, Peng Q (2020)
    Selective Killing of Activated T Cells by 5-Aminolevulinic Acid Mediated Photodynamic Effect: Potential Improvement of Extracorporeal Photopheresis
    Cancers (Basel), 12 (2)
    DOI 10.3390/cancers12020377, PubMed 32041351
  2. Iversen PO, Sioud M (2020)
    Harnessing the Antiviral-Type Responses Induced by Immunostimulatory siRNAs for Cancer Immunotherapy
    Methods Mol Biol, 2115, 281-287
    DOI 10.1007/978-1-0716-0290-4_16, PubMed 32006407
  3. Mobergslien A, Sioud M (2020)
    Exploring 5'-Biotinylation of the Sense Strand to Improve siRNA Specificity and Potency
    Methods Mol Biol, 2115, 163-170
    DOI 10.1007/978-1-0716-0290-4_9, PubMed 32006400
  4. Sioud M (2020)
    RNA and CRISPR Interferences: Past, Present, and Future Perspectives
    Methods Mol Biol, 2115, 1-22
    DOI 10.1007/978-1-0716-0290-4_1, PubMed 32006392
  5. Sioud M (2020)
    Optimized siRNA Delivery into Primary Immune Cells Using Electroporation
    Methods Mol Biol, 2115, 119-131
    DOI 10.1007/978-1-0716-0290-4_7, PubMed 32006398
  6. Sioud M (2020)
    Unleashing the Therapeutic Potential of Dendritic and T Cell Therapies Using RNA Interference
    Methods Mol Biol, 2115, 259-280
    DOI 10.1007/978-1-0716-0290-4_15, PubMed 32006406
  7. Sioud M (2020)
    Microbial sensing by haematopoietic stem and progenitor cells: Vigilance against infections and immune education of myeloid cells
    Scand J Immunol, 92 (5), e12957
    DOI 10.1111/sji.12957, PubMed 32767789
  8. Sæbøe-Larssen S, Sioud M (2020)
    Improving Dendritic Cell Cancer Vaccine Potency Using RNA Interference
    Methods Mol Biol, 2115, 249-258
    DOI 10.1007/978-1-0716-0290-4_14, PubMed 32006405
  9. Wälchli S, Sioud M (2020)
    Next Generation of Adoptive T Cell Therapy Using CRISPR/Cas9 Technology: Universal or Boosted?
    Methods Mol Biol, 2115, 407-417
    DOI 10.1007/978-1-0716-0290-4_22, PubMed 32006413

Publications 2019

  1. Sioud M (2019)
    Releasing the Immune System Brakes Using siRNAs Enhances Cancer Immunotherapy
    Cancers (Basel), 11 (2)
    DOI 10.3390/cancers11020176, PubMed 30717461
  2. Sioud M (2019)
    Phage Display Libraries: From Binders to Targeted Drug Delivery and Human Therapeutics
    Mol Biotechnol, 61 (4), 286-303
    DOI 10.1007/s12033-019-00156-8, PubMed 30729435
  3. Sioud M, Pettersen S, Ailte I, Fløisand Y (2019)
    Targeted Killing of Monocytes/Macrophages and Myeloid Leukemia Cells with Pro-Apoptotic Peptides
    Cancers (Basel), 11 (8)
    DOI 10.3390/cancers11081088, PubMed 31370273

Publications 2018

  1. Peng W, de Bruijn HS, Farrell E, Sioud M, Mashayekhi V, Oliveira S, van Dam GM, Roodenburg JLN, Witjes MJH, Robinson DJ (2018)
    Epidermal growth factor receptor (EGFR) density may not be the only determinant for the efficacy of EGFR-targeted photoimmunotherapy in human head and neck cancer cell lines
    Lasers Surg Med, 50 (5), 513-522
    DOI 10.1002/lsm.22930, PubMed 29777587
  2. Sioud M (2018)
    T-cell cross-reactivity may explain the large variation in how cancer patients respond to checkpoint inhibitors
    Scand J Immunol, 87 (3)
    DOI 10.1111/sji.12643, PubMed 29381830
  3. Sioud M, Westby P, Vasovic V, Fløisand Y, Peng Q (2018)
    Development of a new high-affinity human antibody with antitumor activity against solid and blood malignancies
    FASEB J, 32 (9), 5063-5077
    DOI 10.1096/fj.201701544R, PubMed 29913558

Publications 2016

  1. Mobergslien A, Peng Q, Vasovic V, Sioud M (2016)
    Cancer cell-binding peptide fused Fc domain activates immune effector cells and blocks tumor growth
    Oncotarget, 7 (46), 75940-75953
    DOI 10.18632/oncotarget.12445, PubMed 27713158
  2. Sioud M, Nyakas M, Sæbøe-Larssen S, Mobergslien A, Aamdal S, Kvalheim G (2016)
    Diversification of Antitumour Immunity in a Patient with Metastatic Melanoma Treated with Ipilimumab and an IDO-Silenced Dendritic Cell Vaccine
    Case Rep Med, 2016, 9639585
    DOI 10.1155/2016/9639585, PubMed 27504122
  3. Zins K, Schäfer R, Paulus P, Dobler S, Fakhari N, Sioud M, Aharinejad S, Abraham D (2016)
    Frizzled2 signaling regulates growth of high-risk neuroblastomas by interfering with β-catenin-dependent and β-catenin-independent signaling pathways
    Oncotarget, 7 (29), 46187-46202
    DOI 10.18632/oncotarget.10070, PubMed 27323822

Publications 2015

  1. Iversen PO, Sioud M (2015)
    Engineering therapeutic cancer vaccines that activate antitumor immunity
    Methods Mol Biol, 1218, 263-8
    DOI 10.1007/978-1-4939-1538-5_15, PubMed 25319656
  2. Mobergslien A, Sioud M (2015)
    A facile method for interfering with off-target silencing mediated by the sense strand
    Methods Mol Biol, 1218, 293-300
    DOI 10.1007/978-1-4939-1538-5_18, PubMed 25319659
  3. Mobergslien A, Vasovic V, Mathiesen G, Fredriksen L, Westby P, Eijsink VG, Peng Q, Sioud M (2015)
    Recombinant Lactobacillus plantarum induces immune responses to cancer testis antigen NY-ESO-1 and maturation of dendritic cells
    Hum Vaccin Immunother, 11 (11), 2664-73
    DOI 10.1080/21645515.2015.1056952, PubMed 26185907
  4. Sioud M (2015)
    RNA interference: mechanisms, technical challenges, and therapeutic opportunities
    Methods Mol Biol, 1218, 1-15
    DOI 10.1007/978-1-4939-1538-5_1, PubMed 25319642
  5. Sioud M (2015)
    Cytoplasmic delivery of siRNAs to monocytes and dendritic cells via electroporation
    Methods Mol Biol, 1218, 107-15
    DOI 10.1007/978-1-4939-1538-5_6, PubMed 25319647
  6. Sioud M (2015)
    Strategies for siRNA navigation to desired cells
    Methods Mol Biol, 1218, 201-16
    DOI 10.1007/978-1-4939-1538-5_12, PubMed 25319653
  7. Sioud M (2015)
    Overcoming the challenges of siRNA activation of innate immunity: design better therapeutic siRNAs
    Methods Mol Biol, 1218, 301-19
    DOI 10.1007/978-1-4939-1538-5_19, PubMed 25319660
  8. Sioud M (2015)
    Modified 2'-ribose small RNAs function as Toll-like receptor-7/8 antagonists
    Methods Mol Biol, 1218, 483-9
    DOI 10.1007/978-1-4939-1538-5_28, PubMed 25319669
  9. Sioud M, Mobergslien A, Sæbøe-Larssen S (2015)
    Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses
    Methods Mol Biol, 1218, 269-76
    DOI 10.1007/978-1-4939-1538-5_16, PubMed 25319657
  10. Sioud M, Westby P, Olsen JK, Mobergslien A (2015)
    Generation of new peptide-Fc fusion proteins that mediate antibody-dependent cellular cytotoxicity against different types of cancer cells
    Mol Ther Methods Clin Dev, 2, 15043
    DOI 10.1038/mtm.2015.43, PubMed 26605373
  11. Zins K, Sioud M, Aharinejad S, Lucas T, Abraham D (2015)
    Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy
    Methods Mol Biol, 1218, 143-61
    DOI 10.1007/978-1-4939-1538-5_9, PubMed 25319650

Publications 2014

  1. Sioud M (2014)
    Engineering better immunotherapies via RNA interference
    Hum Vaccin Immunother, 10 (11), 3165-74
    DOI 10.4161/hv.29754, PubMed 25483669

Publications 2013

  1. Mobergslien A, Sioud M (2013)
    Exosome-derived miRNAs and cellular miRNAs activate innate immunity
    J Innate Immun, 6 (1), 105-10
    DOI 10.1159/000351460, PubMed 23774807
  2. Shahzidi S, Brech A, Sioud M, Li X, Suo Z, Nesland JM, Peng Q (2013)
    Lamin A/C cleavage by caspase-6 activation is crucial for apoptotic induction by photodynamic therapy with hexaminolevulinate in human B-cell lymphoma cells
    Cancer Lett, 339 (1), 25-32
    DOI 10.1016/j.canlet.2013.07.026, PubMed 23916608
  3. Sioud M, Saebøe-Larssen S, Hetland TE, Kaern J, Mobergslien A, Kvalheim G (2013)
    Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients
    Int J Oncol, 43 (1), 280-8
    DOI 10.3892/ijo.2013.1922, PubMed 23620105
  4. Sioud M, Skorstad G, Mobergslien A, Sæbøe-Larssen S (2013)
    A novel peptide carrier for efficient targeting of antigens and nucleic acids to dendritic cells
    FASEB J, 27 (8), 3272-83
    DOI 10.1096/fj.12-224758, PubMed 23671272
  5. Zins K, Thomas A, Lucas T, Sioud M, Aharinejad S, Abraham D (2013)
    Inhibition of stromal PlGF suppresses the growth of prostate cancer xenografts
    Int J Mol Sci, 14 (9), 17958-71
    DOI 10.3390/ijms140917958, PubMed 24005860

Publications 2012

  1. Sioud M, Mobergslien A (2012)
    Efficient siRNA targeted delivery into cancer cells by gastrin-releasing peptides
    Bioconjug Chem, 23 (5), 1040-9
    DOI 10.1021/bc300050j, PubMed 22443209
  2. Sioud M, Mobergslien A (2012)
    Selective killing of cancer cells by peptide-targeted delivery of an anti-microbial peptide
    Biochem Pharmacol, 84 (9), 1123-32
    DOI 10.1016/j.bcp.2012.08.002, PubMed 22922046

Publications 2011

  1. Mobergslien A, Sioud M (2011)
    Galectin-1 and -3 gene silencing in immature and mature dendritic cells enhances T cell activation and interferon-γ production
    J Leukoc Biol, 91 (3), 461-7
    DOI 10.1189/jlb.0711361, PubMed 22167721
  2. Sioud M (2011)
    Promises and challenges in developing RNAi as a research tool and therapy
    Methods Mol Biol, 703, 173-87
    DOI 10.1007/978-1-59745-248-9_12, PubMed 21125490
  3. Sioud M (2011)
    New insights into mesenchymal stromal cell-mediated T-cell suppression through galectins
    Scand J Immunol, 73 (2), 79-84
    DOI 10.1111/j.1365-3083.2010.02491.x, PubMed 21198747

Publications 2010

  1. Abraham D, Zins K, Sioud M, Lucas T, Schäfer R, Stanley ER, Aharinejad S (2010)
    Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma
    Int J Cancer, 126 (6), 1339-52
    DOI 10.1002/ijc.24859, PubMed 19711348
  2. Ben-Mahrez K, Sioud M (2010)
    Presence of STRA-STRB linked streptomycin-resistance genes in clinical isolate of Escherichia coil 2418
    Arch Inst Pasteur Tunis, 87 (1-2), 77-81
    PubMed 21598829
  3. Cekaite L, Clancy T, Sioud M (2010)
    Increased miR-21 expression during human monocyte differentiation into DCs
    Front Biosci (Elite Ed), 2 (3), 818-28
    DOI 10.2741/e143, PubMed 20515755
  4. Fløisand Y, Sioud M (2010)
    Recent advances in hematopoietic stem cell transplantation and perspectives of RNAi applications
    Methods Mol Biol, 629, 507-23
    DOI 10.1007/978-1-60761-657-3_30, PubMed 20387168
  5. Fredriksen L, Mathiesen G, Sioud M, Eijsink VG (2010)
    Cell wall anchoring of the 37-kilodalton oncofetal antigen by Lactobacillus plantarum for mucosal cancer vaccine delivery
    Appl Environ Microbiol, 76 (21), 7359-62
    DOI 10.1128/AEM.01031-10, PubMed 20851975
  6. Iversen PO, Sørensen DR, Sioud M (2010)
    A combined immunostimulatory and immunoinhibitory short interference RNA reduces hypercoagulability in a rat model of acute promyelocytic leukaemia
    Thromb Haemost, 104 (2), 350-4
    DOI 10.1160/TH09-12-0816, PubMed 20539915
  7. Mobergslien A, Sioud M (2010)
    Optimized protocols for siRNA delivery into monocytes and dendritic cells
    Methods Mol Biol, 629, 71-85
    DOI 10.1007/978-1-60761-657-3_5, PubMed 20387143
  8. Sioud M (2010)
    Recent advances in small interfering RNA sensing by the immune system
    N Biotechnol, 27 (3), 236-42
    DOI 10.1016/j.nbt.2010.02.015, PubMed 20219711
  9. Sioud M (2010)
    Advances in RNA sensing by the immune system: separation of siRNA unwanted effects from RNA interference
    Methods Mol Biol, 629, 33-52
    DOI 10.1007/978-1-60761-657-3_3, PubMed 20387141
  10. Sioud M (2010)
    What are the key targeted delivery technologies of siRNA now?
    Methods Mol Biol, 629, 93-107
    DOI 10.1007/978-1-60761-657-3_7, PubMed 20387145
  11. Sioud M (2010)
    Development of TLR7/8 small RNA antagonists
    Methods Mol Biol, 629, 387-94
    DOI 10.1007/978-1-60761-657-3_25, PubMed 20387163
  12. Sioud M (2010)
    Modulation of dendritic cell maturation and function by siRNA-bearing 5'-triphosphate
    Methods Mol Biol, 629, 395-404
    DOI 10.1007/978-1-60761-657-3_26, PubMed 20387164
  13. Sioud M (2010)
    Overcoming self-tolerance to tumour cells
    Methods Mol Biol, 629, 495-505
    DOI 10.1007/978-1-60761-657-3_29, PubMed 20387167
  14. Sioud M (2010)
    RNA therapeutics: function, design, and delivery. Preface
    Methods Mol Biol, 629, v-vii
    DOI 10.1007/978-1-60761-657-3, PubMed 20394129
  15. Sioud M, Cekaite L (2010)
    Profiling of miRNA expression and prediction of target genes
    Methods Mol Biol, 629, 257-71
    DOI 10.1007/978-1-60761-657-3_16, PubMed 20387154
  16. Sioud M, Mobergslien A, Boudabous A, Fløisand Y (2010)
    Evidence for the involvement of galectin-3 in mesenchymal stem cell suppression of allogeneic T-cell proliferation
    Scand J Immunol, 71 (4), 267-74
    DOI 10.1111/j.1365-3083.2010.02378.x, PubMed 20384870
  17. Sioud M, Mobergslien A, Boudabous A, Fløisand Y (2010)
    Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins
    Int J Oncol, 38 (2), 385-90
    DOI 10.3892/ijo.2010.869, PubMed 21165555
  18. Sørensen DR, Sioud M (2010)
    Systemic delivery of synthetic siRNAs
    Methods Mol Biol, 629, 87-91
    DOI 10.1007/978-1-60761-657-3_6, PubMed 20387144

Publications 2009

  1. Aharinejad S, Sioud M, Lucas T, Abraham D (2009)
    Targeting stromal-cancer cell interactions with siRNAs
    Methods Mol Biol, 487, 243-66
    DOI 10.1007/978-1-60327-547-7_12, PubMed 19301651
  2. Cekaite L, Hovig E, Sioud M (2009)
    Monitoring B cell response to immunoselected phage-displayed peptides by microarrays
    Methods Mol Biol, 524, 273-85
    DOI 10.1007/978-1-59745-450-6_20, PubMed 19377952
  3. Flatekval GF, Sioud M (2009)
    Modulation of dendritic cell maturation and function with mono- and bifunctional small interfering RNAs targeting indoleamine 2,3-dioxygenase
    Immunology, 128 (1 Suppl), e837-48
    DOI 10.1111/j.1365-2567.2009.03093.x, PubMed 19740345
  4. Hauge H, Fjelland KE, Sioud M, Aasheim HC (2009)
    Evidence for the involvement of FAM110C protein in cell spreading and migration
    Cell Signal, 21 (12), 1866-73
    DOI 10.1016/j.cellsig.2009.08.001, PubMed 19698782
  5. Iversen PO, Semaeva E, Sorensen DR, Wiig H, Sioud M (2009)
    Dendritic Cells Loaded with Tumor Antigens and a Dual Immunostimulatory and Anti-Interleukin 10-Specific Small Interference RNA Prime T Lymphocytes against Leukemic Cells
    Transl Oncol, 2 (4), 242-6
    DOI 10.1593/tlo.09154, PubMed 19956385
  6. Sioud M (2009)
    Deciphering the code of innate immunity recognition of siRNAs
    Methods Mol Biol, 487, 41-59
    DOI 10.1007/978-1-60327-547-7_2, PubMed 19301641
  7. Sioud M (2009)
    Targeted delivery of antisense oligonucleotides and siRNAs into mammalian cells
    Methods Mol Biol, 487, 61-82
    DOI 10.1007/978-1-60327-547-7_3, PubMed 19301642
  8. Sioud M (2009)
    Does our current understanding of immune tolerance, autoimmunity, and immunosuppressive mechanisms facilitate the design of efficient cancer vaccines?
    Scand J Immunol, 70 (6), 516-25
    DOI 10.1111/j.1365-3083.2009.02326.x, PubMed 19906192
  9. Sioud M, Boudabous A, Cekaite L (2009)
    Transcriptional responses of Bacillus subtillis and thuringiensis to antibiotics and anti-tumour drugs
    Int J Mol Med, 23 (1), 33-9
    DOI 10.3892/ijmm_00000098, PubMed 19082504
  10. Sioud M, Fløisand Y (2009)
    NOD2/CARD15 on bone marrow CD34+ hematopoietic cells mediates induction of cytokines and cell differentiation
    J Leukoc Biol, 85 (6), 939-46
    DOI 10.1189/jlb.1008650, PubMed 19244164

Publications 2008

  1. Abraham D, Zins K, Sioud M, Lucas T, Aharinejad S (2008)
    Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts
    Front Biosci, 13, 5571-9
    DOI 10.2741/3100, PubMed 18508606
  2. Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J, Sakariassen PØ, Sandal T, Lønning PE, Flatmark T, Enger PØ, Bjerkvig R, Sioud M, Stallcup WB (2008)
    The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling
    Oncogene, 27 (39), 5182-94
    DOI 10.1038/onc.2008.157, PubMed 18469852
  3. Shadidi M, Sørensen D, Dybwad A, Furset G, Sioud M (2008)
    Mucosal vaccination with phage-displayed tumour antigens identified through proteomics-based strategy inhibits the growth and metastasis of 4T1 breast adenocarcinoma
    Int J Oncol, 32 (1), 241-7
    PubMed 18097564
  4. Sioud M (2008)
    Does the understanding of immune activation by RNA predict the design of safe siRNAs?
    Front Biosci, 13, 4379-92
    DOI 10.2741/3011, PubMed 18508517
  5. Sioud M, Cekaite L (2008)
    Expression profiling of microRNAs in cancer cells: technical considerations
    Methods Mol Biol, 439, 179-90
    DOI 10.1007/978-1-59745-188-8_12, PubMed 18370103
  6. Walchli S, Sioud M (2008)
    Vector-based delivery of siRNAs: in vitro and in vivo challenges
    Front Biosci, 13, 3488-93
    DOI 10.2741/2943, PubMed 18508450

Publications 2007

  1. Aharinejad S, Sioud M, Lucas T, Abraham D (2007)
    Target validation using RNA interference in solid tumors
    Methods Mol Biol, 361, 227-38
    DOI 10.1385/1-59745-208-4:227, PubMed 17172715
  2. Cekaite L, Hovig E, Sioud M (2007)
    Protein arrays: a versatile toolbox for target identification and monitoring of patient immune responses
    Methods Mol Biol, 360, 335-48
    DOI 10.1385/1-59745-165-7:335, PubMed 17172738
  3. Furset G, Fløisand Y, Sioud M (2007)
    Impaired expression of indoleamine 2, 3-dioxygenase in monocyte-derived dendritic cells in response to Toll-like receptor-7/8 ligands
    Immunology, 123 (2), 263-71
    DOI 10.1111/j.1365-2567.2007.02695.x, PubMed 17725606
  4. Røsok Ø, Sioud M (2007)
    Discovery of differentially expressed genes: technical considerations
    Methods Mol Biol, 360, 115-29
    DOI 10.1385/1-59745-165-7:115, PubMed 17172727
  5. Sioud M (2007)
    Main approaches to target discovery and validation
    Methods Mol Biol, 360, 1-12
    DOI 10.1385/1-59745-165-7:1, PubMed 17172722
  6. Sioud M (2007)
    An overview of the immune system and technical advances in tumor antigen discovery and validation
    Methods Mol Biol, 360, 277-318
    DOI 10.1385/1-59745-165-7:277, PubMed 17172735
  7. Sioud M (2007)
    RNA interference and innate immunity
    Adv Drug Deliv Rev, 59 (2-3), 153-63
    DOI 10.1016/j.addr.2007.03.006, PubMed 17459518
  8. Sioud M, Fløisand Y (2007)
    TLR agonists induce the differentiation of human bone marrow CD34+ progenitors into CD11c+ CD80/86+ DC capable of inducing a Th1-type response
    Eur J Immunol, 37 (10), 2834-46
    DOI 10.1002/eji.200737112, PubMed 17853407
  9. Sioud M, Furset G, Cekaite L (2007)
    Suppression of immunostimulatory siRNA-driven innate immune activation by 2'-modified RNAs
    Biochem Biophys Res Commun, 361 (1), 122-6
    DOI 10.1016/j.bbrc.2007.06.177, PubMed 17658482
  10. Sioud M, Leirdal M (2007)
    Druggable signaling proteins
    Methods Mol Biol, 361, 1-24
    DOI 10.1385/1-59745-208-4:1, PubMed 17172705
  11. Sioud M, Melien O (2007)
    Treatment options and individualized medicine
    Methods Mol Biol, 361, 327-40
    DOI 10.1385/1-59745-208-4:327, PubMed 17172721
  12. Zins K, Abraham D, Sioud M, Aharinejad S (2007)
    Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway
    Cancer Res, 67 (3), 1038-45
    DOI 10.1158/0008-5472.CAN-06-2295, PubMed 17283136

Publications 2006

  1. Angell-Petersen E, Spetalen S, Madsen SJ, Sun CH, Peng Q, Carper SW, Sioud M, Hirschberg H (2006)
    Influence of light fluence rate on the effects of photodynamic therapy in an orthotopic rat glioma model
    J Neurosurg, 104 (1), 109-17
    DOI 10.3171/jns.2006.104.1.109, PubMed 16509154
  2. Cekaite L, Furset G, Hovig E, Sioud M (2006)
    Gene expression analysis in blood cells in response to unmodified and 2'-modified siRNAs reveals TLR-dependent and independent effects
    J Mol Biol, 365 (1), 90-108
    DOI 10.1016/j.jmb.2006.09.034, PubMed 17054988
  3. Furset G, Sioud M (2006)
    Design of bifunctional siRNAs: combining immunostimulation and gene-silencing in one single siRNA molecule
    Biochem Biophys Res Commun, 352 (3), 642-9
    DOI 10.1016/j.bbrc.2006.11.059, PubMed 17150189
  4. Huynh T, Wälchli S, Sioud M (2006)
    Transcriptional targeting of small interfering RNAs into cancer cells
    Biochem Biophys Res Commun, 350 (4), 854-9
    DOI 10.1016/j.bbrc.2006.09.127, PubMed 17034763
  5. Sioud M (2006)
    Innate sensing of self and non-self RNAs by Toll-like receptors
    Trends Mol Med, 12 (4), 167-76
    DOI 10.1016/j.molmed.2006.02.004, PubMed 16530484
  6. Sioud M (2006)
    Ribozymes and siRnas: from structure to preclinical applications
    Handb Exp Pharmacol (173), 223-42
    DOI 10.1007/3-540-27262-3_11, PubMed 16594618
  7. Sioud M (2006)
    Single-stranded small interfering RNA are more immunostimulatory than their double-stranded counterparts: a central role for 2'-hydroxyl uridines in immune responses
    Eur J Immunol, 36 (5), 1222-30
    DOI 10.1002/eji.200535708, PubMed 16609928
  8. Sioud M (2006)
    RNA interference below the immune radar
    Nat Biotechnol, 24 (5), 521-2
    DOI 10.1038/nbt0506-521, PubMed 16680132
  9. Sioud M (2006)
    RNAi therapy: antibodies guide the way
    Gene Ther, 13 (3), 194-5
    DOI 10.1038/, PubMed 17243203
  10. Sioud M, Fløisand Y, Forfang L, Lund-Johansen F (2006)
    Signaling through toll-like receptor 7/8 induces the differentiation of human bone marrow CD34+ progenitor cells along the myeloid lineage
    J Mol Biol, 364 (5), 945-54
    DOI 10.1016/j.jmb.2006.09.054, PubMed 17049554
  11. Sioud M, Furset G (2006)
    Molecular basis for the immunostimulatory potency of small interfering RNAs
    J Biomed Biotechnol, 2006 (4), 23429
    DOI 10.1155/JBB/2006/23429, PubMed 17057361
  12. Sioud M, Haoudi A (2006)
    RNA interference
    J Biomed Biotechnol, 2006 (4), 89018
    DOI 10.1155/JBB/2006/89018, PubMed 17057373

Publications 2005

  1. Patzke S, Hauge H, Sioud M, Finne EF, Sivertsen EA, Delabie J, Stokke T, Aasheim HC (2005)
    Identification of a novel centrosome/microtubule-associated coiled-coil protein involved in cell-cycle progression and spindle organization
    Oncogene, 24 (7), 1159-73
    DOI 10.1038/sj.onc.1208267, PubMed 15580290
  2. Røsok O, Sioud M (2005)
    Systematic search for natural antisense transcripts in eukaryotes (review)
    Int J Mol Med, 15 (2), 197-203
    PubMed 15647831
  3. Sioud M (2005)
    Induction of inflammatory cytokines and interferon responses by double-stranded and single-stranded siRNAs is sequence-dependent and requires endosomal localization
    J Mol Biol, 348 (5), 1079-90
    DOI 10.1016/j.jmb.2005.03.013, PubMed 15854645
  4. Sioud M (2005)
    siRNA delivery in vivo
    Methods Mol Biol, 309, 237-49
    DOI 10.1385/1-59259-935-4:237, PubMed 15990404
  5. Sioud M (2005)
    On the delivery of small interfering RNAs into mammalian cells
    Expert Opin Drug Deliv, 2 (4), 639-51
    DOI 10.1517/17425247.2.4.639, PubMed 16296791
  6. Sioud M, Iversen PO (2005)
    Ribozymes, DNAzymes and small interfering RNAs as therapeutics
    Curr Drug Targets, 6 (6), 647-53
    DOI 10.2174/1389450054863653, PubMed 16178798
  7. Sioud M, Røsok Ø (2005)
    High-throughput analysis of microRNA gene expression using sensitive probes
    Methods Mol Biol, 309, 311-20
    DOI 10.1385/1-59259-935-4:311, PubMed 15990410
  8. Sioud M, Wälchli S (2005)
    Strategies for the design of random siRNA libraries and the selection of anti-GFP siRNAs
    Methods Mol Biol, 309, 83-91
    DOI 10.1385/1-59259-935-4:083, PubMed 15990399

Publications 2004

  1. Aharinejad S, Paulus P, Sioud M, Hofmann M, Zins K, Schäfer R, Stanley ER, Abraham D (2004)
    Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
    Cancer Res, 64 (15), 5378-84
    DOI 10.1158/0008-5472.CAN-04-0961, PubMed 15289345
  2. Cekaite L, Haug O, Myklebost O, Aldrin M, Østenstad B, Holden M, Frigessi A, Hovig E, Sioud M (2004)
    Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method
    Proteomics, 4 (9), 2572-82
    DOI 10.1002/pmic.200300768, PubMed 15352232
  3. Hirschberg H, Madsen S, Angell-Petersen E, Peng Q, Sioud M, Sun CH, Sorensen DR (2004)
    Repetitive 5-aminolevulinic acid mediated photodynamic therapy of rat glioma
    P SOC PHOTO-OPT INS, 5312, 405-414
    DOI 10.1117/12.527395
  4. Iversen PO, Sioud M (2004)
    Inhibition of gene expression by nucleic acid enzymes in rodent models of human disease
    Methods Mol Biol, 252, 451-6
    DOI 10.1385/1-59259-746-7:451, PubMed 15017070
  5. Leirdal M, Shadidy M, Røsok Ø, Sioud M (2004)
    Identification of genes differentially expressed in breast cancer cell line SKBR3: potential identification of new prognostic biomarkers
    Int J Mol Med, 14 (2), 217-22
    PubMed 15254768
  6. Leirdal M, Sioud M (2004)
    Gene-array analysis of glioma cells after treatment with an anti-PKCalpha siRNA: a general protocol
    Methods Mol Biol, 252, 493-500
    DOI 10.1385/1-59259-746-7:493, PubMed 15017074
  7. Røsok O, Sioud M (2004)
    An experimental approach for systematic identification of antisense transcripts
    Discov Med, 4 (20), 58-60
    PubMed 20705023
  8. Shadidi M, Sioud M (2004)
    Selection of peptides for specific delivery of oligonucleotides into cancer cells
    Methods Mol Biol, 252, 569-80
    DOI 10.1385/1-59259-746-7:569, PubMed 15017081
  9. Sioud M (2004)
    Therapeutic siRNAs
    Trends Pharmacol Sci, 25 (1), 22-8
    DOI 10.1016/, PubMed 14723975
  10. Sioud M (2004)
    Ribozyme- and siRNA-mediated mRNA degradation: a general introduction
    Methods Mol Biol, 252, 1-8
    DOI 10.1385/1-59259-746-7:001, PubMed 15017038
  11. Sioud M (2004)
    Therapeutic potential of small interfering RNAs
    Drug Future, 29 (7), 741-750
    DOI 10.1358/dof.2004.029.07.854171
  12. Sioud M, Leirdal M (2004)
    Potential design rules and enzymatic synthesis of siRNAs
    Methods Mol Biol, 252, 457-69
    DOI 10.1385/1-59259-746-7:457, PubMed 15017071
  13. Sioud M, Røsok O (2004)
    Profiling microRNA expression using sensitive cDNA probes and filter arrays
    Biotechniques, 37 (4), 574-6, 578-80
    DOI 10.2144/04374ST01, PubMed 15517969
  14. Sioud M, Sørensen DR (2004)
    Systemic delivery of synthetic siRNAs
    Methods Mol Biol, 252, 515-22
    DOI 10.1385/1-59259-746-7:515, PubMed 15017077

Publications 2003

  1. Dybwad A, Lambin P, Sioud M, Zouali M (2003)
    Probing the specificity of human myeloma proteins with a random peptide phage library
    Scand J Immunol, 57 (6), 583-90
    DOI 10.1046/j.1365-3083.2003.01254.x, PubMed 12791097
  2. Røsok Ø, Sioud M (2003)
    Systematic identification of sense-antisense transcripts in mammalian cells
    Nat Biotechnol, 22 (1), 104-8
    DOI 10.1038/nbt925, PubMed 14704709
  3. Shadidi M, Sioud M (2003)
    Selective targeting of cancer cells using synthetic peptides
    Drug Resist Updat, 6 (6), 363-71
    DOI 10.1016/j.drup.2003.11.002, PubMed 14744500
  4. Sioud M, Sørensen D (2003)
    Generation of an effective anti-tumor immunity after immunization with xenogeneic antigens
    Eur J Immunol, 33 (1), 38-45
    DOI 10.1002/immu.200390005, PubMed 12594830
  5. Sioud M, Sørensen DR (2003)
    Cationic liposome-mediated delivery of siRNAs in adult mice
    Biochem Biophys Res Commun, 312 (4), 1220-5
    DOI 10.1016/j.bbrc.2003.11.057, PubMed 14652004
  6. Sørensen DR, Leirdal M, Sioud M (2003)
    Gene silencing by systemic delivery of synthetic siRNAs in adult mice
    J Mol Biol, 327 (4), 761-6
    DOI 10.1016/s0022-2836(03)00181-5, PubMed 12654261

Publications 2002

  1. Iversen PO, Emanuel PD, Sioud M (2002)
    Targeting Raf-1 gene expression by a DNA enzyme inhibits juvenile myelomonocytic leukemia cell growth
    Blood, 99 (11), 4147-53
    DOI 10.1182/blood.v99.11.4147, PubMed 12010819
  2. Leirdal M, Sioud M (2002)
    [Tyrosine kinase receptor-ras-ERK signal transduction pathway as therapeutic tarfet in cancer]
    Tidsskr Nor Laegeforen, 122 (2), 178-82
    PubMed 11873574
  3. Leirdal M, Sioud M (2002)
    Gene silencing in mammalian cells by preformed small RNA duplexes
    Biochem Biophys Res Commun, 295 (3), 744-8
    DOI 10.1016/s0006-291x(02)00736-2, PubMed 12099702
  4. Shadidi M, Sioud M (2002)
    Identification of novel carrier peptides for the specific delivery of therapeutics into cancer cells
    FASEB J, 17 (2), 256-8
    DOI 10.1096/fj.02-0280fje, PubMed 12490548
  5. Sioud M (2002)
    How does autoimmunity cause tumor regression? A potential mechanism involving cross-reaction through epitope mimicry
    Mol Med, 8 (3), 115-9
    DOI 10.1007/BF03402004, PubMed 12142543
  6. Sorensen DR, Leirdal M, Iversen PO, Sioud M (2002)
    Combination of endostatin and a protein kinase Calpha DNA enzyme improves the survival of rats with malignant glioma
    Neoplasia, 4 (6), 474-9
    DOI 10.1038/sj.neo.7900271, PubMed 12407440

Publications 2001

  1. Hansen MH, Ostenstad B, Sioud M (2001)
    Antigen-specific IgG antibodies in stage IV long-time survival breast cancer patients
    Mol Med, 7 (4), 230-9
    DOI 10.1007/BF03401842, PubMed 11471567
  2. Hansen MH, Ostenstad B, Sioud M (2001)
    Identification of immunogenic antigens using a phage-displayed cDNA library from an invasive ductal breast carcinoma tumour
    Int J Oncol, 19 (6), 1303-9
    DOI 10.3892/ijo.19.6.1303, PubMed 11713604
  3. Iversen PO, Nicolaysen G, Sioud M (2001)
    DNA enzyme targeting TNF-alpha mRNA improves hemodynamic performance in rats with postinfarction heart failure
    Am J Physiol Heart Circ Physiol, 281 (5), H2211-7
    DOI 10.1152/ajpheart.2001.281.5.H2211, PubMed 11668085
  4. Melien O, Christoffersen T, Sioud M (2001)
    Evidence for the involvement of Gi2 in activation of extracellular signal-regulated kinases in hepatocytes
    BMC Cell Biol, 2, 13
    DOI 10.1186/1471-2121-2-13, PubMed 11495629
  5. Shadidi M, Sioud M (2001)
    An anti-leukemic single chain Fv antibody selected from a synthetic human phage antibody library
    Biochem Biophys Res Commun, 280 (2), 548-52
    DOI 10.1006/bbrc.2000.4158, PubMed 11162553
  6. Sioud M (2001)
    Nucleic acid enzymes as a novel generation of anti-gene agents
    Curr Mol Med, 1 (5), 575-88
    DOI 10.2174/1566524013363366, PubMed 11899232
  7. Sioud M, Hansen MH (2001)
    Profiling the immune response in patients with breast cancer by phage-displayed cDNA libraries
    Eur J Immunol, 31 (3), 716-25
    DOI 10.1002/1521-4141(200103)31:3<716::aid-immu716>;2-9, PubMed 11241275

Publications 2000

  1. Hansen MH, Dybwad A, Førre O, Sioud M (2000)
    Probing antinuclear antibody specificities by peptide phage display libraries
    Clin Exp Rheumatol, 18 (4), 465-72
    PubMed 10949721
  2. Josefsen D, Myklebust JH, Lømo J, Sioud M, Blomhoff HK, Smeland EB (2000)
    Differential expression of bcl-2 homologs in human CD34(+) hematopoietic progenitor cells induced to differentiate into erythroid or granulocytic cells
    Stem Cells, 18 (4), 261-72
    DOI 10.1634/stemcells.18-4-261, PubMed 10924092
  3. Leirdal M, Sioud M (2000)
    Protein kinase Calpha isoform regulates the activation of the MAP kinase ERK1/2 in human glioma cells: involvement in cell survival and gene expression
    Mol Cell Biol Res Commun, 4 (2), 106-10
    DOI 10.1006/mcbr.2000.0259, PubMed 11170840
  4. Myklebust JH, Smeland EB, Josefsen D, Sioud M (2000)
    Protein kinase C-alpha isoform is involved in erythropoietin-induced erythroid differentiation of CD34(+) progenitor cells from human bone marrow
    Blood, 95 (2), 510-8
    DOI 10.1182/blood.V95.2.510, PubMed 10627456
  5. Sioud M, Hansen M, Dybwad A (2000)
    Profiling the immune responses in patient sera with peptide and cDNA display libraries
    Int J Mol Med, 6 (2), 123-8
    DOI 10.3892/ijmm.6.2.123, PubMed 10891554
  6. Sioud M, Leirdal M (2000)
    Design of nuclease resistant protein kinase calpha DNA enzymes with potential therapeutic application
    J Mol Biol, 296 (3), 937-47
    DOI 10.1006/jmbi.2000.3491, PubMed 10677293
  7. Sioud M, Leirdal M (2000)
    Therapeutic RNA and DNA enzymes
    Biochem Pharmacol, 60 (8), 1023-6
    DOI 10.1016/s0006-2952(00)00395-6, PubMed 11007937

Publications 1999

  1. Leirdal M, Sioud M (1999)
    Ribozyme inhibition of the protein kinase C alpha triggers apoptosis in glioma cells
    Br J Cancer, 80 (10), 1558-64
    DOI 10.1038/sj.bjc.6690560, PubMed 10408397
  2. Sioud M (1999)
    Application of preformed hammerhead ribozymes in the gene therapy of cancer (review)
    Int J Mol Med, 3 (4), 381-4
    DOI 10.3892/ijmm.3.4.381, PubMed 10085409
  3. Sioud M, Leirdal M (1999)
    Substitution of the 2'-hydroxyl group at position 2.1 by an amino group interferes with Mg(2+) binding and efficient cleavage by hammerhead ribozyme
    Biochem Biophys Res Commun, 262 (2), 461-6
    DOI 10.1006/bbrc.1999.1236, PubMed 10462497

Publications 1998

  1. Iversen PO, Sioud M (1998)
    Modulation of granulocyte-macrophage colony-stimulating factor gene expression by a tumor necrosis factor specific ribozyme in juvenile myelomonocytic leukemic cells
    Blood, 92 (11), 4263-8
    DOI 10.1182/blood.V92.11.4263.422k46_4263_4268, PubMed 9834232
  2. Leirdal M, Sioud M (1998)
    High cleavage activity and stability of hammerhead ribozymes with a uniform 2'-amino pyrimidine modification
    Biochem Biophys Res Commun, 250 (1), 171-4
    DOI 10.1006/bbrc.1998.9286, PubMed 9735351
  3. Sioud M, Mellbye O, Førre O (1998)
    Analysis of the NF-kappa B p65 subunit, Fas antigen, Fas ligand and Bcl-2-related proteins in the synovium of RA and polyarticular JRA
    Clin Exp Rheumatol, 16 (2), 125-34
    PubMed 9536387
  4. Sioud M, Sørensen DR (1998)
    A nuclease-resistant protein kinase C alpha ribozyme blocks glioma cell growth
    Nat Biotechnol, 16 (6), 556-61
    DOI 10.1038/nbt0698-556, PubMed 9624687

Publications 1997

  1. Dybwad A, Fłrre O, Sioud M (1997)
    Probing for cerebrospinal fluid antibody specificities by a panel of random peptide libraries
    Autoimmunity, 25 (2), 85-9
    DOI 10.3109/08916939708996274, PubMed 9189009
  2. Sioud M (1997)
    Effects of variations in length of hammerhead ribozyme antisense arms upon the cleavage of longer RNA substrates
    Nucleic Acids Res, 25 (2), 333-8
    DOI 10.1093/nar/25.2.333, PubMed 9016562
  3. Sioud M, Opstad A, Hendry P, Lockett TJ, Jennings PA, McCall MJ (1997)
    A minimised hammerhead ribozyme with activity against interleukin-2 in human cells
    Biochem Biophys Res Commun, 231 (2), 397-402
    DOI 10.1006/bbrc.1997.6099, PubMed 9070287

Publications 1996

  1. Dybwad A, Førre O, Sioud M (1996)
    Increased serum and synovial fluid antibodies to immunoselected peptides in patients with rheumatoid arthritis
    Ann Rheum Dis, 55 (7), 437-41
    DOI 10.1136/ard.55.7.437, PubMed 8774161
  2. Fakhfakh F, Ayadi H, Bahloul Z, Jarraya A, Sioud M, Zouali M (1996)
    Antibody epitopes probed by immunoselected phage-display library peptides in members of a family with various rheumatic manifestations
    Clin Exp Rheumatol, 14 (6), 607-11
    PubMed 8978954
  3. Sioud M (1996)
    Ribozyme modulation of lipopolysaccharide-induced tumor necrosis factor-alpha production by peritoneal cells in vitro and in vivo
    Eur J Immunol, 26 (5), 1026-31
    DOI 10.1002/eji.1830260511, PubMed 8647163
  4. Sioud M, Førre O, Dybwad A (1996)
    Selection of ligands for polyclonal antibodies from random peptide libraries: potential identification of (auto)antigens that may trigger B and T cell responses in autoimmune diseases
    Clin Immunol Immunopathol, 79 (2), 105-14
    DOI 10.1006/clin.1996.0057, PubMed 8620616
  5. Sioud M, Jespersen L (1996)
    Enhancement of hammerhead ribozyme catalysis by glyceraldehyde-3-phosphate dehydrogenase
    J Mol Biol, 257 (4), 775-89
    DOI 10.1006/jmbi.1996.0201, PubMed 8636981
  6. Tougourti MN, Sioud M, Hassen Z, Bouhali R, Hamza M (1996)
    [Psychiatric disorders and endocrine diseases. Apropos of a 8 cases]
    Tunis Med, 74 (12), 549-52
    PubMed 9506057

Publications 1995

  1. Dybwad A, Bogen B, Natvig JB, Førre O, Sioud M (1995)
    Peptide phage libraries can be an efficient tool for identifying antibody ligands for polyclonal antisera
    Clin Exp Immunol, 102 (2), 438-42
    DOI 10.1111/j.1365-2249.1995.tb03802.x, PubMed 7586703
  2. Dybwad A, Førre O, Natvig JB, Sioud M (1995)
    Structural characterization of peptides that bind synovial fluid antibodies from RA patients: a novel strategy for identification of disease-related epitopes using a random peptide library
    Clin Immunol Immunopathol, 75 (1), 45-50
    DOI 10.1006/clin.1995.1051, PubMed 7533685
  3. Kjeldsen-Kragh J, Mellbye OJ, Haugen M, Mollnes TE, Hammer HB, Sioud M, Førre O (1995)
    Changes in laboratory variables in rheumatoid arthritis patients during a trial of fasting and one-year vegetarian diet
    Scand J Rheumatol, 24 (2), 85-93
    DOI 10.3109/03009749509099290, PubMed 7747149
  4. Kjeldsen-Kragh J, Rashid T, Dybwad A, Sioud M, Haugen M, Førre O, Ebringer A (1995)
    Decrease in anti-Proteus mirabilis but not anti-Escherichia coli antibody levels in rheumatoid arthritis patients treated with fasting and a one year vegetarian diet
    Ann Rheum Dis, 54 (3), 221-4
    DOI 10.1136/ard.54.3.221, PubMed 7748020
  5. Ostenstad B, Dybwad A, Lea T, Førre O, Vinje O, Sioud M (1995)
    Evidence for monoclonal expansion of synovial T cells bearing V alpha 2.1/V beta 5.5 gene segments and recognizing a synthetic peptide that shares homology with a number of putative autoantigens
    Immunology, 86 (2), 168-75
    PubMed 7490114
  6. Ostenstad B, Sioud M, Schlichting E, Lea T, Harboe M (1995)
    Freshly isolated tumour-infiltrating T-lymphocytes have a high cytotoxic potential, as measured by their ability to induce apoptosis in the target cell
    Scand J Immunol, 41 (1), 42-8
    DOI 10.1111/j.1365-3083.1995.tb03531.x, PubMed 7824887
  7. Tougourti MN, Sioud M, Hamza M (1995)
    [Cerebrovascular accidents in Horton's disease. Apropos of a case]
    Tunis Med, 73 (5), 195-9
    PubMed 9507283
  8. Tougourti MN, Sioud M, Kheder L, Hamza M, Miled M (1995)
    [Antiphospholipid syndrome]
    Tunis Med, 73 (2), 95-103
    PubMed 9506150

Publications 1994

    NATO ADV SCI INST SE, 80, 191-196
  2. Ostenstad B, Sioud M, Lea T, Schlichting E, Harboe M (1994)
    Limited heterogeneity in the T-cell receptor V-gene usage in lymphocytes infiltrating human colorectal tumours
    Br J Cancer, 69 (6), 1078-82
    DOI 10.1038/bjc.1994.211, PubMed 8198973
  3. Sioud M (1994)
    Interaction between tumour necrosis factor alpha ribozyme and cellular proteins. Involvement in ribozyme stability and activity
    J Mol Biol, 242 (5), 619-29
    DOI 10.1006/jmbi.1994.1612, PubMed 7932719
  4. Sioud M, Dybwad A, Jespersen L, Suleyman S, Natvig JB, Førre O (1994)
    Characterization of naturally occurring autoantibodies against tumour necrosis factor-alpha (TNF-alpha): in vitro function and precise epitope mapping by phage epitope library
    Clin Exp Immunol, 98 (3), 520-5
    DOI 10.1111/j.1365-2249.1994.tb05522.x, PubMed 7994916
  5. Sioud M, Opstad A, Zhao JQ, Levitz R, Benham C, Drlica K (1994)
    In vivo decay kinetic parameters of hammerhead ribozymes
    Nucleic Acids Res, 22 (25), 5571-5
    DOI 10.1093/nar/22.25.5571, PubMed 7838709
  6. Suleyman S, Thompson KM, Førre O, Sioud M, Randen I, Mageed RA, Natvig JB (1994)
    Three new cross-reacting idiotopes as markers for the products of two distinct human VH3 genes expressed in the early repertoire
    Scand J Immunol, 40 (6), 681-90
    DOI 10.1111/j.1365-3083.1994.tb03524.x, PubMed 7527936
  7. Tougourti MN, Sioud M, Khedher I, Houman H, Hamza M, Miled M (1994)
    [Iatrogenic accidents in the hospital environment]
    Tunis Med, 72 (11), 625-30
    PubMed 7762090

Publications 1993

  1. Dybwad A, Førre O, Kjeldsen-Kragh J, Natvig JB, Sioud M (1993)
    Identification of new B cell epitopes in the sera of rheumatoid arthritis patients using a random nanopeptide phage library
    Eur J Immunol, 23 (12), 3189-93
    DOI 10.1002/eji.1830231222, PubMed 7504991
  2. Førre O, Sioud M (1993)
    T cell receptor variable region gene usage in juvenile chronic arthritis
    Clin Exp Rheumatol, 11 Suppl 9, S43-6
    PubMed 8354007
  3. Kjeldsen-Kragh J, Quayle AJ, Skålhegg BS, Sioud M, Førre O (1993)
    Selective activation of resting human gamma delta T lymphocytes by interleukin-2
    Eur J Immunol, 23 (9), 2092-9
    DOI 10.1002/eji.1830230908, PubMed 8370391
  4. Suleyman S, Hosono O, Sioud M, Randen I, Thompson KM, Førre O, Natvig JB (1993)
    Differentiation of human lambda I variable regions with a monoclonal antibody to a defined, germ-line-encoded idiotope correlates with V lambda Ia chemical structure
    J Immunol, 150 (12), 5466-75
    PubMed 8515071

Publications 1992

  1. Quayle AJ, Wilson KB, Li SG, Kjeldsen-Kragh J, Oftung F, Shinnick T, Sioud M, Førre O, Capra JD, Natvig JB (1992)
    Peptide recognition, T cell receptor usage and HLA restriction elements of human heat-shock protein (hsp) 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid
    Eur J Immunol, 22 (5), 1315-22
    DOI 10.1002/eji.1830220529, PubMed 1577070
  2. Sioud M, Kjeldsen-Kragh J, Suleyman S, Vinje O, Natvig JB, Førre O (1992)
    Limited heterogeneity of T cell receptor variable region gene usage in juvenile rheumatoid arthritis synovial T cells
    Eur J Immunol, 22 (9), 2413-8
    DOI 10.1002/eji.1830220934, PubMed 1387614
  3. Sioud M, Natvig JB, Førre O (1992)
    Preformed ribozyme destroys tumour necrosis factor mRNA in human cells
    J Mol Biol, 223 (4), 831-5
    DOI 10.1016/0022-2836(92)90244-e, PubMed 1538398
  4. Waalen K, Sioud M, Natvig JB, Førre O (1992)
    Spontaneous in vivo gene transcription of interleukin-2, interleukin-3, interleukin-4, interleukin-6, interferon-gamma, interleukin-2 receptor (CD25) and proto-oncogene c-myc by rheumatoid synovial T lymphocytes
    Scand J Immunol, 36 (6), 865-73
    DOI 10.1111/j.1365-3083.1992.tb03148.x, PubMed 1462123

Publications 1991

  1. Sioud M, Drlica K (1991)
    Prevention of human immunodeficiency virus type 1 integrase expression in Escherichia coli by a ribozyme
    Proc Natl Acad Sci U S A, 88 (16), 7303-7
    DOI 10.1073/pnas.88.16.7303, PubMed 1871136
  2. Sioud M, Førre O, Natvig JB (1991)
    T cell receptor delta diversity of freshly isolated T lymphocytes in rheumatoid synovitis
    Eur J Immunol, 21 (1), 239-41
    DOI 10.1002/eji.1830210137, PubMed 1825059
  3. Sioud M, Kjeldsen-Kragh J, Quayle AJ, Wiker HG, Sørskaar D, Natvig JB, Førre O (1991)
    Immune responses to 18.6 and 30-kDa mycobacterial antigens in rheumatoid patients, and V beta usage by specific synovial T-cell lines and fresh T cells
    Scand J Immunol, 34 (6), 803-12
    DOI 10.1111/j.1365-3083.1991.tb01605.x, PubMed 1836278

Publications 1990

  1. Pascual V, Randen I, Thompson K, Sioud M, Forre O, Natvig J, Capra JD (1990)
    The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes
    J Clin Invest, 86 (4), 1320-8
    DOI 10.1172/JCI114841, PubMed 2170450
  2. Sioud M, Kjeldsen-Kragh J, Quayle A, Kalvenes C, Waalen K, Førre O, Natvig JB (1990)
    The V delta gene usage by freshly isolated T lymphocytes from synovial fluids in rheumatoid synovitis: a preliminary report
    Scand J Immunol, 31 (4), 415-21
    DOI 10.1111/j.1365-3083.1990.tb02787.x, PubMed 1692153

Publications 1989

  1. Forterre P, Elie C, Sioud M, Hamal A (1989)
    Studies on DNA polymerases and topoisomerases in archaebacteria
    Can J Microbiol, 35 (1), 228-33
    DOI 10.1139/m89-035, PubMed 2541877
  2. Quayle A, Kjeldsen-Kragh J, Førre O, Waalen K, Sioud M, Kalvenes C, Natvig JB (1989)
    Immunoregulatory T cell subsets and T cell activation in rheumatoid arthritis. A need for analysis on the clonal and molecular level
    Springer Semin Immunopathol, 11 (3), 273-87
    DOI 10.1007/BF00197307, PubMed 2575800
  3. Sioud M, Forterre P (1989)
    Ciprofloxacin and etoposide (VP16) produce a similar pattern of DNA cleavage in a plasmid of an archaebacterium
    Biochemistry, 28 (9), 3638-41
    DOI 10.1021/bi00435a002, PubMed 2751986

Publications 1988

  1. Sioud M, Baldacci G, de Recondo AM, Forterre P (1988)
    Inhibitors of DNA topoisomerase II induce topological changes in an archaebacterial plasmid in vivo
    Biochem Pharmacol, 37 (9), 1879-80
    DOI 10.1016/0006-2952(88)90492-3, PubMed 2837247
  2. Sioud M, Baldacci G, de Recondo AM, Forterre P (1988)
    Novobiocin induces positive supercoiling of small plasmids from halophilic archaebacteria in vivo
    Nucleic Acids Res, 16 (4), 1379-91
    DOI 10.1093/nar/16.4.1379, PubMed 3347494
  3. Sioud M, Baldacci G, Forterre P, de Recondo AM (1988)
    Novobiocin induces accumulation of a single strand of plasmid pGRB-1 in the archaebacterium Halobacterium GRB
    Nucleic Acids Res, 16 (16), 7833-42
    DOI 10.1093/nar/16.16.7833, PubMed 3419901
  4. Sioud M, Possot O, Elie C, Sibold L, Forterre P (1988)
    Coumarin and quinolone action in archaebacteria: evidence for the presence of a DNA gyrase-like enzyme
    J Bacteriol, 170 (2), 946-53
    DOI 10.1128/jb.170.2.946-953.1988, PubMed 2828337

Publications 1987

  1. Sioud M, Baldacci G, Forterre P, de Recondo AM (1987)
    Antitumor drugs inhibit the growth of halophilic archaebacteria
    Eur J Biochem, 169 (2), 231-6
    DOI 10.1111/j.1432-1033.1987.tb13602.x, PubMed 3121311
  2. Sioud M, Forterre P, de Recondo AM (1987)
    Effects of the antitumor drug VP16 (etoposide) on the archaebacterial Halobacterium GRB 1.7 kb plasmid in vivo
    Nucleic Acids Res, 15 (20), 8217-34
    DOI 10.1093/nar/15.20.8217, PubMed 3671082

Publications 1986

  1. Bernard M, Sioud M, Percheron F, Foglietti MJ (1986)
    beta-Mannosidase in human serum and urine. A comparative study
    Int J Biochem, 18 (11), 1065-8
    DOI 10.1016/0020-711x(86)90255-7, PubMed 3803698

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