Translational Neurodegeneration Research & Neuropathology
The lab mainly performs animal model based research on neurodegenerative diseases with special emphasis on Alzheimer’s disease. We develop mouse models that recapitulate impaired clearance mechanisms occurring in sporadic Alzheimer’s disease that will allow us to specifically define the impact of certain cell types at distinct point during disease progression. Furthermore, we develop/improve drugs and screen plant extracts for their ability to reduce amyloid pathology in our mouse models with aiming translation into clinical trials.
Main Pahnke lab home page: www.pahnkelab.eu