Translational Neurodegeneration Research & Neuropathology
This combined research and diagnostic lab is located at Rikshospitalet. We provide daily diagnostic service for brain biopsy diagnostics, muscle disease diagnostics, routine autopsy diagnostics for adults, kids and fetuses, and forensic neuropathology consultations. Our research focuses on basic and molecular neurodegeneration research, translational projects, patient-related treatment and diagnostic research. We have several unique mouse lines located at the Radium Hospital mouse facility.
Lauritzen T, Munkhaugen J, Bergan S, Peersen K, Svarstad AC, Andersen AM, Pahnke J, Husebye E, Vethe NT(2024) The atorvastatin metabolite pattern in muscle tissue and blood plasma is associated with statin muscle side effects in patients with coronary heart disease; An exploratory case-control study Atheroscler Plus, 55, 31-38 DOI 10.1016/j.athplu.2024.01.001, PubMed 38293288
El Menuawy A, Brüning T, Eiriz I, Hähnel U, Marthe F, Möhle L, Górska AM, Santos-García I, Wangensteen H, Wu J, Pahnke J(2024) Apolar Extracts of St. John's Wort Alleviate the Effects of β-Amyloid Toxicity in Early Alzheimer's Disease Int J Mol Sci, 25(2) DOI 10.3390/ijms25021301, PubMed 38279301
Hernández-Lozano I, Leterrier S, Mairinger S, Stanek J, Zacher AS, Breyer L, Hacker M, Zeitlinger M, Pahnke J, Tournier N, Wanek T, Langer O(2024) Performance and Sensitivity of [99mTc]Tc-sestamibi Compared with Positron Emission Tomography Radiotracers to Measure P-glycoprotein Function in the Kidneys and Liver Mol Pharm, 21(2), 932-943 DOI 10.1021/acs.molpharmaceut.3c01036, PubMed 38225758